JOURNAL
PAPER
(*
corresponding author; published cover article;
PDF version of paper
; &co-first author)
Total SCI Publications: 170+;
Google Scholar Citations: 13,000+; Google Scholar H-index: 63
Publications of Year 2024 (click
to show or hide the details)
-
L. Y.
Zheng, S. Y. Shi, M. K. Lu, P. Fang, Z. Q. Pan, H. N. Zhang, Z.
M. Zhou, H. Y. Zhang, M. J. Mou, S. J. Huang, L. Tao, W. Q. Xia,
H. L. Li, Z. Y. Zeng, S. Zhang, Y. Z. Chen, Z. R. Li*, F.
Zhu*. AnnoPRO: a
strategy for protein function annotation based on multi-scale
protein representation and a hybrid deep learning of dual-path
encoding.
Genome
Biology
(impact
factor of the publication year: 12.3, 生物一区
TOP
期刊). 25(1):41 (2024). PMID: 38303023.
-
Y. Zhou, Y.
T. Zhang, D. H. Zhao, X. Y. Yu, X. Y. Shen, Y. Zhou, S. S. Wang, Y.
Q. Qiu, Y. Z. Chen*, F. Zhu*. TTD: therapeutic
target database describing target druggability information.
Nucleic Acids
Research
(impact factor of the publication year: 14.9,
生物二区 TOP 期刊). 52(D1): 1465-1477 (2024). PMID: 37713619.
-
L. T.
Shen, X. N. Sun, Z. Chen, Y. Guo, Z. Y. Shen, Y. Song, W. X. Xin, H.
Y. Ding, X. Y. Ma, W. B. Xu, W. Y. Zhou, J. X. Che, L. L. Tan, L.
S. Chen, S. Q. Chen, X. W. Dong*, L. Fang*, F. Zhu*. ADCdb: the
database of antibody-drug conjugates.
Nucleic Acids
Research
(impact factor of the publication year: 14.9,
生物二区 TOP 期刊). 52(D1): 1097-1109 (2024). PMID: 37831118.
-
Y. T.
Zhang, Y. Zhou, Y. Zhou, X. Y. Yu, X. Y. Shen, Y. F. Hong, Y. X.
Zhang, S. S. Wang, M. J. Mou, J. S. Zhang, L. Tao, J. Q. Gao, Y. Q.
Qiu*, Y. Z. Chen*, F. Zhu*. TheMarker: a
comprehensive database of therapeutic biomarkers.
Nucleic Acids
Research
(impact factor of the publication year: 14.9,
生物二区 TOP 期刊). 52(D1): 1450-1464 (2024). PMID: 37850638.
Cover Article:
-
The
Cover Article
of Nucleic Acids Res 2024 52(D1), Download the Cover
.
-
X. C. Lian, Y.
T. Zhang, Y. Zhou, X. N. Sun, S. J. Huang, H. B. Dai*, L. Y. Han*, F.
Zhu*. SingPro: a knowledge
base providing single-cell proteomic data.
Nucleic Acids
Research
(impact
factor of the publication year: 14.9, 生物二区 TOP
期刊). 52(D1): 552-561 (2024). PMID: 37819028.
-
J. Y. Yin,
Z. Chen, N. X. You, F. C. Li, H. Y. Zhang, J. Xue, H. Ma, Q. W.
Zhao, L. S. Yu*, S. Zeng*, F. Zhu*. VARIDT 3.0: the
phenotypic and regulatory variability of drug transporter.
Nucleic Acids
Research
(impact factor of the publication year: 14.9,
生物二区 TOP 期刊). 52(D1): 1490-1502 (2024). PMID: 37819041.
-
Y. Zhang,
X. G. Liu, F. C. Li, J. Y. Yin, H. Yang, X. D. Li, X. Y. Liu, X.
Chai, T. L. Niu, S. Zeng*, Q. Z. Jia*, F. Zhu*. INTEDE 2.0: the
metabolic roadmap of drugs.
Nucleic Acids
Research
(impact factor of the publication year: 14.9,
生物二区 TOP 期刊). 52(D1): 1355-1364 (2024). PMID: 37930837.
-
Y.
Zhang, H. C. Sun, W. Zhang, T. T. Fu, S. J. Huang, M. J. Mou, J. S.
Zhang, J. Q. Gao, Y. C. Ge*, Q. X. Yang*, F. Zhu*. CellSTAR: a
comprehensive resource for single-cell transcriptomic annotation.
Nucleic Acids
Research
(impact factor of the publication year: 14.9,
生物二区 TOP 期刊). 52(D1): 859-870 (2024). PMID: 37855686.
-
L. Y.
Zheng, S. Y. Shi, X. N. Sun, M. K. Lu, Y. Liao, S. S.
Zhu, H. N. Zhang, Z. Q. Pan, P. Fang, Z. Y. Zeng, H. L.
Li, Z. R. Li*, W. W. Xue*, F. Zhu*.
MoDAFold: a strategy for predicting the structure of
missense mutant protein based on AlphaFold2 and
molecular dynamics.
Briefings in Bioinformatics
(impact factor of the publication year:
9.5,
生物二区
TOP 期刊). 25(2): bbae006 (2024). PMID: 38305456.
-
H. Q. Xu,
H. Xiao, J. H. Bu, Y. F. Hong, Y. H. Liu, Z. Y. Tao, S. F. Ding, Y.
T. Xia, E. Wu, Z. Yan, W. Zhang, G. X. Chen, F. Zhu*, L. Tao*. EMNPD: a
comprehensive endophytic microorganism natural products database for
prompt the discovery of new bioactive substances.
Journal of
Cheminformatics
(impact factor of the publication year: 8.6,
化学二区期刊). 15(1): c115 (2024). PMID: 38017550.
-
J. Y. Yin,
H. Y. Zhang, X. N. Sun, N. X. You, M. J. Mou, M. K. Lu, Z. Q. Pan,
F. C. Li, H. L. Li*, S. Zeng*, F. Zhu*. Decoding drug
response with structurized gridding map-based cell representation.
IEEE Journal of
Biomedical and Health Informatics
(impact factor of the publication year: 7.7,
工程技术一区 TOP 期刊). doi: 10.1109/JBHI.2023.3342280 (2024). PMID: 38090819.
-
K. Amahong,
W. Zhang, Y. H. Liu, T. Li, S. J. Huang, L. Y. Han*, L. Tao*, F.
Zhu*. RVvictor: virus
RNA-directed molecular interactions for RNA virus infection.
Computers in
Biology and Medicine
(impact factor of the publication year: 7.7,
工程技术二区期刊). 169: 107886 (2024). PMID: 38157777.
-
Q. X.
Yang, S. M. Chen, W. Y. Jiang, L. Mi, J. R. Liu, Y. Hu,
X. L. Ji*, J. Wang*, F. Zhu*.
MultiClassMetabo: superior classification model
constructed using metabolic markers in multiclass
metabolomics.
Analytical Chemistry
(impact factor of the publication year:
7.4,
化学一区
TOP 期刊). 96(4):1410-1418 (2024). PMID: 38221713.
-
J. Tang, M.
J. Mou, X. Zheng, J. Yan, Z. Q. Pan, J. S. Zhang, B. Li, Q. X. Yang,
Y. X. Wang, Y. Zhang, J. Q. Gao, S. Li*, H. Yang*, F. Zhu*. Strategy for identifying a robust metabolomic signature reveals the altered lipid metabolism in pituitary adenoma.
Analytical
Chemistry
(impact factor of the publication year: 7.4,
化学一区 TOP 期刊). doi: 10.1021/acs.analchem.3c03796 (2024). PMID: 38417094.
-
C. F. Xu,
J. T. Huang, Y. Q. Gao, W. X. Zhao, Y. Q. Shen, F. H.
Luo, G. Yu, F. Zhu*, Y.
Ni*. OBMeta: a comprehensive web server to analyze and
validate gut microbial features and biomarkers for
obesity-associated metabolic diseases.
Bioinformatics
(impact factor of the publication year:
6.9,
生物二区
TOP 期刊). 39(12):btad715 (2023). PMID: 38078817.
-
W. Zhang,
M. J. Mou, W. Hu, M. K. Lu, H. Y. Zhang, H. N. Zhang, Y. C. Luo, H.
Q. Xu, L. Tao, H. B. Dai, J. Q. Gao*, F. Zhu*. MOINER: a novel
multi-omics early integration framework for biomedical
classification and biomarker discovery.
Journal of
Chemical Information and Modeling
(impact factor of the publication year: 5.6,
化学二区 TOP 期刊). doi: 10.1021/acs.jcim.4c00013 (2024). PMID: 38373720.
-
H. Li, H.
Seada, S. Madnick, H. Zhao, Z. Z. Chen, F. C. Li, F. Zhu, S.
Hall, K. Boekelheide*. Machine learning-assisted high-content
imaging analysis of 3D MCF7 microtissues for estrogenic effect
prediction.
Scientific
Reports
(impact factor of the publication year: 4.6,
化学二区期刊). 14(1): 2999 (2024). PMID: 38316851.
Publications of Year 2023 (click
to show or hide the details)
-
Y. X. Wang, Z.
Q. Pan, M. J. Mou, W. Q. Xia, H. N. Zhang, H. Y. Zhang, J. Liu, L. Y.
Zheng, Y. C. Luo, H. Q. Zheng, X. Y. Yu, X. C. Lian, Z. Y. Zeng, Z. R.
Li, B. Zhang, M. Y. Zheng, H. L. Li, T. J. Hou, F. Zhu*. A task-specific
encoding algorithm for RNAs and RNA-associated interactions based on
convolutional autoencoder.
Nucleic Acids
Research
(impact
factor of the publication year: 19.2, 生物二区 TOP
期刊). 51(21): e110 (2023). PMID: 37889083.
-
M. J. Mou,
Z. Q. Pan, Z. M. Zhou, L. Y. Zheng, H. Y. Zhang, S. Y. Shi, F. C.
Li, X. N. Sun, F. Zhu*. A
transformer-based ensemble framework for the prediction of
protein-protein interaction sites.
Research
(impact factor of the publication year: 11.0,
综合一区 TOP 期刊). 6: 0240 (2023). PMID: 37771850.
Media Coverage & News Report:
-
Y. Zhang,
H. C. Sun, X. C. Lian, J. Tang, F. Zhu*. ANPELA:
significantly enhanced quantification tool for cytometry-based
single-cell proteomics.
Advanced Science
(impact factor of the publication year: 17.5,
工程技术一区 TOP 期刊). 10(15): e2207061 (2023). PMID: 36950745.
Cover Article:
-
M. K. Lu,
J. Y. Yin, Q. Zhu, G. L. Lin, M. J. Mou, F. Y. Liu, Z.
Q. Pan, N. X. You, X. C. Lian, F. C. Li, H. N. Zhang, L.
Y. Zheng, W. Zhang, H. Y. Zhang, Z. H. Shen, Z. Gu, H.
L. Li*, F. Zhu*.
Artificial intelligence in pharmaceutical sciences.
Engineering
(impact factor of the publication year:
12.8,
工程技术一区
TOP 期刊). 27: 37-69 (2023). PMID:
N.A.
-
Y. X. Wang,
Z. Chen, Z. Q. Pan, S. J. Huang, J. Liu, W. Q. Xia, H. N. Zhang, M.
Y. Zheng, H. L. Li, T. J. Hou, F. Zhu*. RNAincoder: a deep
learning-based encoder for RNA and RNA-associated interaction.
Nucleic Acids
Research
(impact factor of the publication year: 19.2,
生物一区 TOP 期刊). 51(W1): 509-519 (2023). PMID: 37166951.
-
F. C. Li,
J. Y. Yin, M. K. Lu, M. J. Mou, Z. R. Li, Z. Y. Zeng, Y. Tan, S. S.
Wang, X. Y. Chu, H. B. Dai, T. J. Hou, S. Zeng*, Y. Z. Chen*, F.
Zhu*. DrugMAP: molecular
atlas and pharma-information of all drugs.
Nucleic Acids
Research
(impact factor of the publication year: 19.2,
生物一区 TOP 期刊). 51(D1): 1288-1299 (2023). PMID: 36243961.
Cover Article:
-
The
Cover Article
of Nucleic Acids Res 2023 51(D1), Download the Cover
.
Media Coverage & News Report:
-
K. Amahong,
W. Zhang, Y. Zhou, S. Zhang, J. Y. Yin, F. C. Li, H. Q. Xu, T. C,
Yan, Z. X. Yue, Y. H. Liu, T. J. Hou, Y. Q. Qiu, L. Tao*, L. Y.
Han*, F. Zhu*. CovInter:
interaction data between coronavirus RNAs and host proteins.
Nucleic Acids
Research
(impact factor of the publication year: 19.2,
生物一区 TOP 期刊). 51(D1): 546-556 (2023). PMID: 36200814.
Media Coverage & News Report:
-
CPS@ZJU. Oct 14th, 2022.
-
eBiotrade. Oct 25th, 2022.
-
ECHEMI.com. Oct 31th, 2022.
-
FMP@ZJU. Oct 14th, 2022.
-
Genome Web. Oct 10th, 2022.
-
Gen Online. Oct 25th, 2022.
-
Innovative Hangzhou. Oct 20th, 2022.
-
IPM-GBA. Nov 9th, 2022.
-
India Education Diary. Nov 4th, 2022.
-
LIFE BOAT. Nov 9th, 2022.
-
Mirage News. Nov 2th, 2022.
-
Net of Instrument Info. Oct 18th, 2022.
-
PHYS.ORG. Nov 2th, 2022.
-
STA@ZJU. Oct 24th, 2022.
-
Quietly Positive. Nov 2th, 2022.
-
Science Week. Nov 2th, 2022.
-
ZJU Newsroom. Nov 2th, 2022.
-
Zhejiang University. Oct 17th, 2022.
-
X. N. Sun,
Y. T. Zhang, H. Y. Li, Y. Zhou, S. Y. Shi, Z. Chen, X. He, H. Y.
Zhang, F. C. Li, J. Y. Yin, M. J. Mou, Y. Z. Wang, Y. Q. Qiu, F.
Zhu*. DRESIS: the first
comprehensive landscape of drug resistance information.
Nucleic Acids
Research
(impact factor of the publication year: 19.2,
生物一区 TOP 期刊). 51(D1): 1263-1275 (2023). PMID: 36243960.
Media Coverage & News Report:
-
Antpedia. Apr 17th, 2023.
-
AutophagyAdvances. Mar 3th, 2023.
-
bilibili. Fer 3th, 2023.
-
CPS@ZJU. Mar 4th, 2023.
-
CSDN. Apr 12th, 2023.
-
eBiotrade. Mar 3th, 2023.
-
iBioinformatics. Apr 14th, 2023.
-
JinriArticle. Mar 3th, 2023.
-
SciRes. Apr 15th, 2023.
-
Sohu. Apr 25th, 2023.
-
Zhihu. Apr 25th, 2023.
-
S. P. Liu,
L. Chen, Y. T. Zhang, Y. Zhou, Y. He, Z. Chen, S. S. Qi, J. Y. Zhu,
X. D. Chen, H. Zhang, Y. C. Luo, Y. Q. Qiu, L. Tao*, F. Zhu*. M6AREG:
m6A-centered regulation of disease development and drug response.
Nucleic Acids
Research
(impact factor of the publication year: 19.2,
生物一区 TOP 期刊). 51(D1): 1333-1344 (2023). PMID: 36134713.
Media Coverage & News Report:
-
J. B. Fu,
Q. X. Yang, Y. C. Luo, S. Zhang, J. Tang, Y. Zhang, H. N. Zhang, H.
X. Xu, F. Zhu*. Label-free
proteome quantification and evaluation.
Briefings in
Bioinformatics
(impact factor of the publication year: 13.9,
生物二区 TOP 期刊). 24(1): bbac477 (2023). PMID: 36403090.
-
H. N.
Zhang, M. K. Lu, G. L. Lin, L. Y. Zheng, W. Zhang, Z. J. Xu, F.
Zhu*. SoCube: an
innovative end-to-end doublet detection algorithm for analyzing
scRNA-seq data.
Briefings in
Bioinformatics
(impact factor of the publication year: 13.9,
生物二区 TOP 期刊). 24(3): bbad104 (2023). PMID: 36941114.
-
Y. C. Luo,
P. P. Wang, M. J. Mou, H. Q. Zheng, J. J. Hong, L. Tao, F.
Zhu*. A novel strategy
for designing the magic shotguns for distantly related target pairs.
Briefings in
Bioinformatics
(impact factor of the publication year: 13.9,
生物二区 TOP 期刊). 24(1): bbac621 (2023). PMID: 36631399.
-
Q. X.
Yang*, Y. G. Gong, F. Zhu*. Critical
assessment of the biomarker discovery and classification methods for
multiclass metabolomics.
Analytical
Chemistry
(impact factor of the publication year: 8.0,
化学一区 TOP 期刊). 95(13): 5542-5552 (2023). PMID: 36944135.
-
W. Hu, T.
T. Jin, Z. Q. Pan, H. M. Xu, L. Y. Yu, T. T. Chen, W. Zhang, H. F.
Jiang, W. J. Yang, J. J. Xu, F. Zhu*, H. B. Dai*. An
interpretable ensemble learning model facilitates early risk
stratification of ischemic stroke in intensive care unit:
development and external validation of ICU-ISPM.
Computers in
Biology and Medicine
(impact factor of the publication year: 7.7,
工程技术二区期刊). 166: 107577 (2023). PMID: 37852108.
-
S. Zhang,
K. Amahong, Y. T. Zhang, X. P. Hu, S. J. Huang, M. K. Lu, Z. Y.
Zeng, Z. R. Li, B. Zhang, Y. Q. Qiu, H. B. Dai, J. Q. Gao, F.
Zhu*. RNAenrich: a web
server for non-coding RNA enrichment.
Bioinformatics
(impact factor of the publication year: 6.9,
生物二区 TOP 期刊). 39(7): btad421 (2023). PMID: 37399102.
-
K. M.
Merz, G. W. Wei, F. Zhu*. Editorial
harnessing the power of large language model-based chatbots for
scientific discovery.
Journal of
Chemical Information and Modeling
(impact factor of the publication year: 6.2,
化学二区期刊). 63(17): 5395 (2023). PMID: 37691490.
-
W. Hu, W.
Zhang, Y. Zhou, Y. C. Luo, X. N. Sun, H. M. Xu, S. Y. Shi, T. Li, Y.
C. Xu, Q. Q. Yang, Y. Q. Qiu, F. Zhu*, H. B. Dai*.
MecDDI: clarified drug-drug interaction mechanism facilitating
rational drug use and potential drug-drug interaction prediction.
Journal of
Chemical Information and Modeling
(impact factor of the publication year: 6.2,
化学二区期刊). 63(5): 1626-1636 (2023). PMID: PMID: 36802582.
-
H. Q.
Xu, W. Zhang, Y. Zhou, Z. X. Yue, T. C. Yan, Y. Y. Zhang, Y. H.
Liu, Y. F. Hong, S. P. Liu*, F. Zhu*, L. Tao*.
Systematic description of the content variation of natural products
(NPs): to prompt the yield of high-value NPs and the discovery of
new therapeutics.
Journal of
Chemical Information and Modeling
(impact factor of the publication year: 6.2,
化学二区期刊). 63(5): 1615-1625 (2023). PMID: 36795011.
-
K. M. Merz,
G. W. Wei, F. Zhu*. Editorial machine
learning in bio-cheminformatics.
Journal of
Chemical Information and Modeling
(impact factor of the publication year: 6.2,
化学二区期刊). 63(1): 1 (2023). PMID: 36617996.
-
Y. Zhou, Y.
T. Zhang, F. C. Li, X. C. Lian, Q. Zhu, F. Zhu*, Y. Q. Qiu*.
SISPRO: signature identification for spatial proteomics.
Journal of
Molecular Biology
(impact factor of the publication year: 6.2,
生物二区 TOP 期刊). 435(14): 167944 (2023). PMID: 37356911.
-
T. T. Fu,
S. Zeng, Q. C. Zheng*, F. Zhu*. The important role
of transporter structures in drug disposition, efficacy, and
toxicity.
Drug Metabolism
and Disposition
(impact factor of the publication year: 3.9,
医学二区期刊). 51(10): 1316-1323 (2023). PMID: 37295948.
-
J. Y. Yin,
N. X. You, F. C. Li, M. K. Lu, S. Zeng*, F. Zhu*. State-of-the-art
application of artificial intelligence to transporter-centered
functional and pharmaceutical research.
Current Drug
Metabolism
(impact factor of the publication year: 3.4, 医学三区期刊). 24(3): 162-174 (2023). PMID: 37226790.
-
J. B. Fu,
F. Zhu, C. J. Xu, Y. Li*. Metabolomics meets systems
immunology.
EMBO Reports
(impact factor of the publication year: 9.0, 生物二区期刊). 24(4): e55747 (2023). PMID: 36916532.
-
Q. Ye, R.
L. Xu, D. Li, Y. Kang, Y. F. Deng, F. Zhu, J. M. Chen*, S. B.
He, C. Y. Hsieh*, T. J. Hou*. Integrating multi-modal deep learning
on knowledge graph for the discovery of synergistic drug
combinations against infectious diseases.
Cell Reports
Physical Science
(impact factor of the publication year: 8.9, 综合二区期刊). 4(8): 101520 (2023). PMID: N.A.
-
S. Z.
Deng, H. W. Zhang*, R. P. Gou, D. Luo, Z. R. Liu, F. Zhu, W.
W. Xue*. Structure-based discovery of a novel allosteric inhibitor
against human dopamine transporter.
Journal of
Chemical Informatisson and Modeling
(impact factor of the publication year: 6.2, 化学二区期刊). 63(14): 4458-4467 (2023). PMID: 37410882.
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L. D. Wang,
X. Liang, H. Chen, L. J. Cao, L. Liu, F. Zhu, Y. B. Ding*, J.
Tang*, Y. L. Xie*. CDEMI: characterizing differences in microbial
composition and function in microbiome data.
Computational and
Structural Biotechnology Journal
(impact factor of the publication year: 6.2, 生物二区期刊). 21: 2502-2513 (2023). PMID: 37090432.
Publications of Year 2022 (click
to show or hide the details)
-
J. B. Fu, Y.
Zhang, Y. X. Wang, H. N. Zhang, J. Liu, J. Tang, Q. X. Yang, H. C. Sun,
W. Q. Qiu, Y. H. Ma, Z. R. Li, M. Y. Zheng, F. Zhu*. Optimization of
metabolomic data processing using NOREVA.
Nature Protocols
(impact
factor of the publication year: 17.0, 生物一区 TOP
期刊). 17(1): 129-151 (2022). PMID: 34952956.
Featured Article:
ESI Highly Cited Paper:
-
The Percentile in Subject Area shown in
InCites™
was 0.26% in 2023.
Media Coverage & News Report:
-
Beijing Academy of AI. Dec 31th, 2021.
-
Chowdera.com. Dec 31th, 2021.
-
CPS@ZJU. Dec 30th, 2021.
-
Chinese ZhiHu. Dec 31th, 2021.
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DrugAI. Dec 31th, 2021.
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eBiotrade. Jan 1th, 2022.
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ECHEMI.com. Jan 27th, 2022.
-
Gene Online. Jan 1th, 2022.
-
India Education Diary. Jan 28th, 2022.
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Mirage News. Jan 27th, 2022.
-
Neurons AI. Jan 27th, 2022.
-
NSF@Zhejiang. Jan 24th, 2022.
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Tencent Cloud. Jan 1th, 2022.
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ZJU Newsroom. Jan 26th, 2022.
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Zhejiang University. Dec 30th, 2021.
-
T. T. Fu,
F. C. Li, Y. Zhang, J. Y. Yin, W. Q. Qiu, X. D. Li, X. G. Liu, W. W.
Xin, C. Z. Wang, L. S. Yu, J. Q. Gao, Q. C. Zheng*, S. Zeng*, F.
Zhu*. VARIDT 2.0:
structural variability of drug transporter.
Nucleic Acids
Research
(impact factor of the publication year: 19.2,
生物一区 TOP 期刊). 50(D1): 1417-1431 (2022). PMID: 34747471.
Media Coverage & News Report:
-
X. N. Wang,
F. C. Li, W. Q. Qiu, B. B. Xu, Y. L. Li, X. C. Lian, H. Y. Yu, Z.
Zhang, J. X. Wang, Z. R. Li, W. W. Xue*, F. Zhu*. SYNBIP: synthetic
binding proteins for research, diagnosis and therapy.
Nucleic Acids
Research
(impact factor of the publication year: 19.2,
生物一区 TOP 期刊). 50(D1): 560-570 (2022). PMID: 34664670.
Media Coverage & News Report:
-
Y. Zhou, Y.
T. Zhang, X. C. Lian, F. C. Li, C. X. Wang, F. Zhu*, Y. Q. Qiu*, Y. Z.
Chen*. Therapeutic target database update 2022: facilitating drug
discovery with enriched comparative data of targeted agents.
Nucleic Acids
Research
(impact factor of the publication year: 19.2,
生物一区 TOP 期刊). 50(D1): 1398-1407 (2022). PMID: 34718717.
ESI Highly Cited Paper:
-
The Percentile in Subject Area shown in
InCites™
was 0.35% in 2023.
Media Coverage & News Report:
-
X. N. Sun,
Y. T. Zhang, Y. Zhou, X. C. Lian, L. L. Yan, T. Pan, T. Jin, H. Xie,
Z. M. Liang, W. Q. Qiu, J. X. Wang, Z. R. Li, F. Zhu*, X. B. Sui*. NPCDR:
natural product-based drug combination and its disease-specific
molecular regulation.
Nucleic Acids
Research
(impact factor of the publication year: 19.2,
生物一区 TOP 期刊). 50(D1): 1324-1333 (2022). PMID: 34664659.
-
Q. X. Yang,
B. Li, P. P. Wang, J. C. Xie, Y. H. Feng, Z. Q. Liu, F. Zhu*. LargeMetabo: an
out-of-the-box tool for processing and analyzing large-scale
metabolomic data.
Briefings in
Bioinformatics
(impact factor of the publication year: 13.9,
生物一区 TOP 期刊). 23(6): bbac455 (2022). PMID: 36274234.
-
H. Y.
Zhang, Y. X. Wang, Z. Q. Pan, X. N. Sun, M. J. Mou, B. Zhang, Z. R.
Li, H. L. Li*, F. Zhu*. ncRNAInter: a
novel strategy based on graph neural network to discover
interactions between lncRNA and miRNA.
Briefings in
Bioinformatics
(impact factor of the publication year: 13.9,
生物一区 TOP 期刊). 23(6): bbac411 (2022). PMID: 36198065.
-
S. Zhang,
K. Amahong, C. Y. Zhang, F. C. Li, J. Q. Gao, Y. Q. Qiu*, F.
Zhu*. RNA-RNA
interactions between SARS-CoV-2 and host benefit viral development
and evolution during COVID-19 infection.
Briefings in
Bioinformatics
(impact factor of the publication year: 13.9,
生物一区 TOP 期刊). 23(1): bbab397 (2022). PMID: 34585235.
ESI Highly Cited Paper:
-
The Percentile in Subject Area shown in
InCites™
was 0.12% in
2023.
-
F. C. Li,
Y. Zhou, Y. Zhang, J. Y. Yin, Y. Q. Qiu, J. Q. Gao, F. Zhu*. POSREG: proteomic
signature discovered by simultaneously optimizing its
reproducibility and generalizability.
Briefings in
Bioinformatics
(impact factor of the publication year: 13.9,
生物一区 TOP 期刊). 23(2): bbac040 (2022). PMID: 35183059.
ESI Highly Cited Paper:
-
The Percentile in Subject Area shown in
InCites™
was 0.06% in
2023.
-
F. C. Li,
J. Y. Yin, M. K. Lu, Q. X. Yang, Z. Y. Zeng, B. Zhang, Z. R. Li, Y.
Q. Qiu, H. B. Dai, Y. Z. Chen*, F. Zhu*. ConSIG: consistent
discovery of molecular signature from OMIC data.
Briefings in
Bioinformatics
(impact factor of the publication year: 13.9,
生物一区 TOP 期刊). 23(4): bbac253 (2022). PMID: 35758241.
-
C. Y.
Zhang, M. J. Mou, Y. Zhou, W. Zhang, X. C. Lian, S. Y. Shi, M. K.
Lu, H. C. Sun, F. C. Li, Y. X. Wang, Z. Y. Zeng, Z. R. Li, B. Zhang,
Y. Q. Qiu, F. Zhu*, J. Q. Gao*.
Biological activities of drug inactive ingredients (DIGs).
Briefings in
Bioinformatics
(impact factor of the publication year: 13.9,
生物一区 TOP 期刊). 23(5): bbac160 (2022). PMID: 35524477.
-
S. Zhang,
X. N. Sun, M. J. Mou, K. Amahong, H. C. Sun, W. Zhang, S. Y. Shi, Z.
R. Li, J. Q. Gao, F. Zhu*. REGLIV: molecular
regulation data of diverse living systems facilitating current
multiomics research.
Computers in
Biology and Medicine
(impact factor of the publication year: 7.7,
工程技术二区期刊). 148: 105825 (2022). PMID: 35872412.
-
W. Q. Xia,
L. Y. Zheng, J. B. Fang, F. C. Li, Y. Zhou, Z. Y. Zeng, B. Zhang, Z.
R. Li, H. L. Li*, F. Zhu*. PFmulDL: a novel
strategy enabling multi-class and multi-label protein function
annotation by integrating diverse deep learning methods.
Computers in
Biology and Medicine
(impact factor of the publication year: 7.7,
工程技术二区期刊). 145: 105465 (2022). PMID: 35366467.
ESI Highly Cited Paper:
-
The Percentile in Subject Area shown in
InCites™
was 0.40% in 2023.
-
M. J.
Mou, Z. Q. Pan, M. K. Lu, H. C. Sun, Y. X. Wang, Y. C. Luo, F.
Zhu*. Application of
machine learning in spatial proteomics.
Journal of
Chemical Information and Modeling
(impact factor of the publication year: 6.2,
化学二区期刊). 62(23): 5875-5895 (2022). PMID: 36378082.
Cover Article:
-
The
Cover Article
of J Chem Inf Model 2022 62(23), Download the Cover
.
-
L. D. Wang,
W. Zhang, X. L. Wu, X. Liao, L. J. Cao, J. C. Zhai, Y. Y. Yang, Q.
X. Chen, H. Q. Liu, J. Zhang, Y. B. Ding*, F. Zhu*, J. Tang*. MIAOME:
human microbiome affect the host epigenome.
Computational and
Structural Biotechnology Journal
(impact factor of the publication year: 6.2,
生物二区期刊). 20: 2455-2463 (2022). PMID: 35664224.
-
W. W. Xue,
T. T. Fu, S. Z. Deng, F. Y. Yang, J. Y. Yang, F. Zhu*. Molecular
mechanism for the allosteric inhibition of the human serotonin
transporter by antidepressant escitalopram.
ACS Chemical
Neuroscience
(impact factor of the publication year: 5.8,
医学二区期刊). 13(3): 340-351 (2022). PMID: 35041375.
ESI Highly Cited Paper:
-
The Percentile in Subject Area shown in
InCites™
was 0.05% in
2023.
-
The Percentile in Subject Area shown in
InCites™
was 0.09% in
2022.
-
F. Y. Yang,
J. Y. Yang, Z. Zhang, G. Tu, X. J. Yao, W. W. Xue*, F. Zhu*. Recent advances in
computer-aided antiviral drug design targeting HIV-1 integrase and
reverse transcriptase associated ribonuclease H.
Current Medicinal
Chemistry
(impact factor of the publication year: 4.7, 医学三区期刊). 29(10): 1664-1676 (2022). PMID: 34238145.
-
J. Y. Yin,
F. C. Li, Z. R. Li, L. S. Yu, F. Zhu*, S. Zeng*. Feature, function,
and information of drug transporter related databases.
Drug Metabolism
and Disposition
(impact factor of the publication year: 3.9,
医学二区期刊). 50(1): 76-85 (2022). PMID: 34426411.
Cover Article:
-
The
Cover Article
of Drug Metab Dispos 2022 50(1), Download the Cover
.
-
J. P. Pang,
X. P. Hu, Y. X. Wang, J. N. Liao, X. Chai, X. W. Wang, C. Shen, J.
J. Wang, L. L. Zhang, X. Y. Wang, F. Zhu, Q. J. Weng, L. Xu,
T. J. Hou, D. Li*. Discovery of a novel nonsteroidal selective
glucocorticoid receptor modulator by virtual screening and
bioassays.
Acta
Pharmacologica Sinica
(impact factor of the publication year: 8.2, 医学一区 TOP
期刊). 43(9): 2429-2438 (2022). PMID: 35110698.
-
J. P. Pang,
C. Shen, W. F. Zhou, Y. X. Wang, L. H. Shan, X. Chai, Y. Shao, X. P.
Hu, F. Zhu, D. Y. Zou, L. Xiao, L. Xu, X. H. Xu, D. Li*, T.
J. Hou*. Discovery of novel antagonists targeting the DNA binding
domain of androgen receptor by integrated docking-based virtual
screening and bioassays.
Acta
Pharmacologica Sinica
(impact factor of the publication year: 8.2, 医学一区 TOP
期刊). 43(1): 229-239 (2022). PMID: 33767381.
-
H. C. Zhao,
S. K. Wang, K. Zheng, Q. C. Zhao, F. Zhu, J. X. Wang*. A
similarity-based deep learning approach for determining the
frequencies of drug side effects.
Briefings in
Bioinformatics
(impact factor of the publication year: 13.9, 生物一区
TOP 期刊). 23(1): bbab449 (2022). PMID: 34718402.
-
G. W. Wei,
F. Zhu, K. M. Merz*. Editorial on machine learning.
Journal of
Chemical Information and Modeling
(impact factor of the publication year: 6.2, 化学二区期刊). 62(17): 3941 (2022). PMID: 36044023.
-
G. W. Wei*,
T. A. Soares, H. Wahab, F. Zhu. Computational chemistry in
Asia.
Journal of
Chemical Information and Modeling
(impact factor of the publication year: 6.2, 化学二区期刊). 62(21): 5035-5037 (2022). PMID: 36373284.
-
Y. H. Wang,
J. C. Zhai, X. L. Wu, E. A. Adu-Gyamfi, L. P. Yang, T. H. Liu, M. J.
Wang, Y. B. Ding, F. Zhu, Y. X. Wang*, J. Tang*. LncRNA
functional annotation with improved false discovery rate achieved by
disease associations.
Computational and
Structural Biotechnology Journal
(impact factor of the publication year: 6.2, 生物二区期刊). 20: 322-332 (2022). PMID: 35035785.
Publications of Year 2021 (click
to show or hide the details)
-
J. Y. Yin, F.
C. Li, Y. Zhou, M. J. Mou, Y. J. Lu, K. L. Chen, J. Xue, Y. C. Luo, J.
B. Fu, X. He, J. Q. Gao, S. Zeng*, L. S. Yu*, F. Zhu*. INTEDE: interactome of
drug-metabolizing enzymes.
Nucleic Acids
Research
(impact
factor of the publication year: 19.2, 生物一区 TOP
期刊). 49(D1): 1233-1243 (2021). PMID: 33045737.
ESI Highly Cited Paper:
-
The Percentile in Subject Area shown in
InCites™
was 1.12% in 2022.
Media Coverage & News Report:
-
J. Tang, X.
L. Wu, M. J. Mou, C. Wang, L. D. Wang, F. C. Li, M. Y. Guo, J. Y.
Yin, W. Q. Xie, X. N. Wang, Y. X. Wang, Y. B. Ding*, W. W. Xue*,
F. Zhu*. GIMICA: host
genetic and immune factors shaping human microbiota.
Nucleic Acids
Research
(impact factor of the publication year: 19.2,
生物一区 TOP 期刊). 49(D1): 715-722 (2021). PMID: 33045729.
Media Coverage & News Report:
-
S. Zhang,
K. Amahong, X. N. Sun, X. C. Lian, J. Liu, H. C. Sun, Y. Lou, F.
Zhu*, Y. Q. Qiu*. The
miRNA: a small but powerful RNA for COVID-19.
Briefings in
Bioinformatics
(impact factor of the publication year: 13.9,
生物一区 TOP 期刊). 22(2): 1137-1149 (2021). PMID: 33675361.
ESI Highly Cited Paper:
-
The Percentile in Subject Area shown in
InCites™
was 0.40% in 2023.
-
The Percentile in Subject Area shown in
InCites™
was 0.79% in 2022.
-
S. Zhang,
Y. Zhou, Y. N. Wang, Z. W. Wang, Q. T. Xiao, Y. Zhang, Y. Lou, Y. Q.
Qiu*, F. Zhu*. The mechanistic,
diagnostic and therapeutic novel nucleic acids for hepatocellular
carcinoma emerging in past score years.
Briefings in
Bioinformatics
(impact factor of the publication year: 13.9,
生物一区 TOP 期刊). 22(2): 1860-1883 (2021). PMID: 32249290.
-
J. B. Fu,
Y. Zhang, J. Liu, X. C. Lian, J. Tang, F. Zhu*.
Pharmacometabonomics: data processing and statistical analysis.
Briefings in
Bioinformatics
(impact factor of the publication year: 13.9,
生物一区 TOP 期刊). 22(5): bbab138 (2021). PMID: 33866355.
-
J. Tang, M.
J. Mou, Y. X. Wang, Y. C. Luo, F. Zhu*. MetaFS:
performance assessment of biomarker discovery in metaproteomics.
Briefings in
Bioinformatics
(impact factor of the publication year: 13.9,
生物一区 TOP 期刊). 22(3): bbaa105 (2021). PMID: 32510556.
ESI Highly Cited Paper:
-
The Percentile in Subject Area shown in
InCites™
was 0.92% in 2023.
-
S. Zhang,
F. Zhu*. Comment on
microRNA mimics or inhibitors as antiviral therapeutic approaches
against COVID-19.
Drugs
(impact factor of the publication year: 11.4,
医学二区 TOP 期刊). 81(14): 1691-1692 (2021). PMID: 34453690.
-
J. Y. Yin,
X. X. Li, F. C. Li, Y. J. Lu, S. Zeng*, F. Zhu*. Identification of
the key target profiles underlying the drugs of narrow therapeutic
index for treating cancer and cardiovascular disease.
Computational and
Structural Biotechnology Journal
(impact factor of the publication year: 7.3,
生物二区期刊). 19: 2318-2328 (2021). PMID: 33995923.
-
T. T. Fu,
G. Tu, M. Ping, G. X. Zheng, F. Y. Yang, J. Y. Yang, Y. Zhang, X. J.
Yao, W. W. Xue*, F. Zhu*. Subtype selective
mechanisms of negative allosteric modulators binding to group I
metabotropic glutamate receptors.
Acta
Pharmacologica Sinica
(impact factor of the publication year: 6.2,
医学一区 TOP 期刊). 42(8): 1354-1367 (2021). PMID: 33122823.
-
G. Tu, T.
T. Fu, F. Y. Yang, J. Y. Yang, Z. Zhang, X. J. Yao, W. W. Xue*,
F. Zhu*. Understanding the
polypharmacological profiles of triple reuptake inhibitors by
molecular simulation.
ACS Chemical
Neuroscience
(impact factor of the publication year: 4.4,
医学二区期刊). 12(11): 2013-2026 (2021). PMID: 33977725.
-
Q. X. Yang,
B. Li, S. J. Chen, J. Tang, Y. H. Li, Y. Li, S. Zhang, C. Shi, Y.
Zhang, M. J. Mou, W. W. Xue*, F. Zhu*. MMEASE: online
meta-analysis of metabolomic data by enhanced metabolite annotation,
marker selection and enrichment analysis.
Journal of
Proteomics
(impact factor of the publication year: 4.0,
生物二区期刊). 232: 104023 (2021). PMID: 33130111.
ESI Highly Cited Paper:
-
The Percentile in Subject Area shown in
InCites™
was 0.69% in 2023.
-
The Percentile in Subject Area shown in
InCites™
was 2.51% in 2022.
-
J. Y. Yang,
Z. Zhang, F. Y. Yang, J. Tang, H. W. Zhang, H. B. Wu, F. Zhu*, W. W. Xue*.
Computational design and modeling of nanobodies toward SARS-CoV-2
receptor binding domain.
Chemical Biology
& Drug Design
(impact factor of the publication year: 2.5, 医学三区期刊). 98(1): 1-18 (2021). PMID: 33894099.
ESI Highly Cited Paper:
-
The Percentile in Subject Area shown in
InCites™
was 2.72% in 2022.
-
W. X. Shen,
X. Zeng, F. Zhu, Y. L. Wang, C. Qin, Y. Tan, Y. Y. Jiang*, Y.
Z. Chen*. Out-of-the-box deep learning prediction of pharmaceutical
properties by broadly learned knowledge-based molecular
representations.
Nature Machine
Intelligence
(impact factor of the publication year: 15.5, 综合一区
TOP 期刊). 3: 334-343 (2021). PMID: N.A.
-
S. Y. Chen,
S. Y. Yang, X. Zeng, F. Zhu, Y. Tan, Y. Y. Jiang*, Y. Z.
Chen*. Combining kinase inhibitors for optimally co-targeting cancer
and drug escape by exploitation of drug target promiscuities.
Drug Development
Research
(impact factor of the publication year: 4.4, 医学四区期刊). 82(1): 133-142 (2021). PMID: 32931039.
Publications of Year 2020 (click
to show or hide the details)
-
Q. X. Yang, Y.
X. Wang, Y. Zhang, F. C. Li, W. Q. Xia, Y. Zhou, Y. Q. Qiu, H. L. Li,
F. Zhu*. NOREVA: enhanced
normalization and evaluation of time-course and multi-class metabolomic
data.
Nucleic Acids
Research
(impact
factor of the publication year: 16.9, 生物一区 TOP
期刊). 48(W1): 436-448 (2020). PMID: 32324219.
ESI Highly Cited Paper:
-
The Percentile in Subject Area shown in
InCites™
was 0.87% in 2023.
-
The Percentile in Subject Area shown in
InCites™
was 1.60% in 2022.
Media Coverage & News Report:
-
Y. X. Wang,
S. Zhang, F. C. Li, Y. Zhou, Y. Zhang, Z. W. Wang, R. Y. Zhang, J.
Zhu, Y. X. Ren, Y. Tan, C. Qin, Y. H. Li, X. X. Li, Y. Z. Chen*,
F. Zhu*. Therapeutic target
database 2020: enriched resource for facilitating research and early
development of targeted therapeutics.
Nucleic Acids
Research
(impact factor of the publication year: 16.9,
生物一区 TOP 期刊). 48(D1): 1031-1041 (2020). PMID: 31691823.
Publication of World-wide Reputation:
ESI Highly Cited Paper:
-
The Percentile in Subject Area shown
in
InCites™
was 0.12% in
2023.
-
The Percentile in Subject Area shown
in
InCites™
was 0.13% in
2022.
-
The Percentile in Subject Area shown
in
InCites™
was 0.15% in
2021.
Media Coverage & News Report:
-
J. Y. Yin,
W. Sun, F. C. Li, J. J. Hong, X. X. Li, Y. Zhou, Y. J. Lu, M. Z.
Liu, X. Zhang, N. Chen, X. P. Jin, J. Xue, S. Zeng*, L. S. Yu*,
F. Zhu*. VARIDT 1.0:
variability of drug transporter database.
Nucleic Acids
Research
(impact factor of the publication year: 16.9,
生物一区 TOP 期刊). 48(D1): 1042-1050 (2020). PMID: 31495872.
ESI Highly Cited Paper:
-
The Percentile in Subject Area shown in
InCites™
was 0.81% in 2023.
-
The Percentile in Subject Area shown in
InCites™
was 0.96% in 2022.
-
The Percentile in Subject Area shown in
InCites™
was 0.33% in 2021.
Media Coverage & News Report:
-
Y. H. Li,
X. X. Li, J. J. Hong, Y. X. Wang, J. B. Fu, H. Yang, C. Y. Yu, F. C.
Li, J. Hu, W. W. Xue, Y. Y. Jiang, Y. Z. Chen*, F. Zhu*. Clinical trials,
progression-speed differentiating features, and swiftness rule of
the innovative targets of first-in-class drugs.
Briefings in
Bioinformatics
(impact factor of the publication year: 11.6,
生物一区 TOP 期刊). 21(2): 649-662 (2020). PMID: 30689717.
ESI Highly Cited Paper:
-
The Percentile in Subject Area shown in
InCites™
was 0.36% in 2023.
-
The Percentile in Subject Area shown in
InCites™
was 0.49% in 2022.
-
The Percentile in Subject Area shown in
InCites™
was 0.09% in 2021.
-
J. Tang, J.
B. Fu, Y. X. Wang, B. Li, Y. H. Li, Q. X. Yang, X. J. Cui, J. J.
Hong, X. F. Li, Y. Z. Chen, W. W. Xue, F. Zhu*. ANPELA: analysis
and performance-assessment of the label-free quantification workflow
for metaproteomic studies.
Briefings in
Bioinformatics
(impact factor of the publication year: 11.6,
生物一区 TOP 期刊). 21(2): 621-636 (2020). PMID: 30649171.
ESI Highly Cited Paper:
-
The Percentile in Subject Area shown in
InCites™
was 0.30% in 2023.
-
The Percentile in Subject Area shown in
InCites™
was 0.20% in 2022.
-
The Percentile in Subject Area shown in
InCites™
was 0.05% in 2021.
-
Q. X. Yang,
B. Li, J. Tang, X. J. Cui, Y. X. Wang, X. F. Li, J. Hu, Y. Z. Chen,
W. W. Xue, Y. Lou, Y. Q. Qiu*, F. Zhu*. Consistent gene
signature of schizophrenia identified by a novel feature selection
strategy from comprehensive sets of transcriptomic data.
Briefings in
Bioinformatics
(impact factor of the publication year: 11.6,
生物一区 TOP 期刊). 21(3): 1058-1068 (2020). PMID: 31157371.
ESI Highly Cited Paper:
-
The Percentile in Subject Area shown in
InCites™
was 0.29% in 2023.
-
The Percentile in Subject Area shown in
InCites™
was 0.56% in 2022.
-
The Percentile in Subject Area shown in
InCites™
was 0.19% in 2021.
-
Z. J. Han,
W. W. Xue, L. Tao, Y. Lou, Y. Q. Qiu*, F. Zhu*. Genome-wide
identification and analysis of the eQTL lncRNAs in multiple
sclerosis based on RNA-seq data.
Briefings in
Bioinformatics
(impact factor of the publication year: 11.6,
生物一区 TOP 期刊). 21(3): 1023-1037 (2020). PMID: 31323688.
ESI Highly Cited Paper:
-
The Percentile in Subject Area shown in
InCites™
was 2.22% in 2022.
-
Q. X. Yang,
J. J. Hong, Y. Li, W. W. Xue, S. Li*, H. Yang*, F. Zhu*. A novel
bioinformatics approach to identify the consistently well-performing
normalization strategy for current metabolomic studies.
Briefings in
Bioinformatics
(impact factor of the publication year: 11.6,
生物一区 TOP 期刊). 21(6): 2142-2152 (2020). PMID: 31776543.
ESI Highly Cited Paper:
-
The Percentile in Subject Area shown in
InCites™
was 2.69% in 2022.
-
J. Tang, Y.
X. Wang, J. B. Fu, Y. Zhou, Y. C. Luo, Y. Zhang, B. Li, Q. X. Yang,
W. W. Xue, Y. Lou, Y. Q. Qiu*, F. Zhu*. A critical
assessment of the feature selection methods used for biomarker
discovery in current metaproteomic studies.
Briefings in
Bioinformatics
(impact factor of the publication year: 11.6,
生物一区 TOP 期刊). 21(4): 1378-1390 (2020). PMID: 31197323.
-
J. J. Hong,
Y. C. Luo, Y. Zhang, J. B. Ying, W. W. Xue, T. Xie, L. Tao*, F.
Zhu*. Protein functional
annotation of simultaneously improved stability, accuracy and false
discovery rate achieved by a sequence-based deep learning.
Briefings in
Bioinformatics
(impact factor of the publication year: 11.6,
生物一区 TOP 期刊). 21(4): 1437-1447 (2020). PMID: 31504150.
ESI Highly Cited Paper:
-
The Percentile in Subject Area shown in
InCites™
was 0.58% in 2023.
-
The Percentile in Subject Area shown in
InCites™
was 0.94% in 2022.
-
J. J. Hong,
Y. C. Luo, M. J. Mou, J. B. Fu, Y. Zhang, W. W. Xue, T. Xie, L.
Tao*, Y. Lou*, F. Zhu*. Convolutional
neural network-based annotation of bacterial type IV secretion
system effectors with enhanced accuracy and reduced false discovery.
Briefings in
Bioinformatics
(impact factor of the publication year: 11.6,
生物一区 TOP 期刊). 21(5): 1825-1836 (2020). PMID: 31860715.
ESI Highly Cited Paper:
-
The Percentile in Subject Area shown in
InCites™
was 0.73% in 2023.
-
The Percentile in Subject Area shown in
InCites™
was 1.18% in 2022.
-
Y. X. Wang,
F. C. Li, Y, Zhang, Y. Zhou, Y. Tan, Y. Z. Chen*, F. Zhu*. Databases for the
targeted COVID-19 therapeutics.
British Journal
of Pharmacology
(impact factor of the publication year: 7.7,
医学二区 TOP 期刊). 177(21): 4999-5001 (2020). PMID: 32845521.
-
J. Tang, Y.
X. Wang, Y. C. Luo, J. B. Fu, Y. Zhang, Y. Li, Z. Y. Xiao, Y. Lou,
Y. Q. Qiu*, F. Zhu*. Computational
advances of tumor marker selection and sample classification in
cancer proteomics.
Computational and
Structural Biotechnology Journal
(impact factor of the publication year: 6.0,
生物二区 TOP 期刊). 18: 2012-2025 (2020). PMID: 32802273.
-
F. C. Li,
Y. Zhou, X. Y. Zhang, J. Tang, Q. X. Yang, Y. Zhang, Y. C. Luo, J.
Hu*, W. W. Xue, Y. Q. Qiu, Q. J. He, B. Yang, F. Zhu*. SSizer:
determining the sample sufficiency for comparative biological study.
Journal of
Molecular Biology
(impact factor of the publication year: 5.1,
生物二区 TOP 期刊). 432(11): 3411-3421 (2020). PMID: 32044343.
-
Y. Zhang,
G. X. Zheng, T. T. Fu, J. J. Hong, F. C. Li, X. J. Yao, W. W. Xue*,
F. Zhu*. The binding mode
of vilazodone in the human serotonin transporter elucidated by
ligand docking and molecular dynamics simulations.
Physical
Chemistry Chemical Physics
(impact factor of the publication year: 4.1,
化学二区 TOP 期刊). 22(9): 5132-5144 (2020). PMID: 32073004.
-
W. W. Xue*,
T. T. Fu, G. X. Zheng, G. Tu, Y. Zhang, F. Y. Yang, L. Tao, L. X.
Yao, F. Zhu*. Recent advances
and challenges of the drugs acting on monoamine transporters.
Current Medicinal
Chemistry
(impact factor of the publication year: 4.2,
医学二区期刊). 27(23): 3830-3876 (2020). PMID: 30306851.
Media Coverage & News Report:
-
J. B. Fu,
Y. C. Luo, M. J. Mou, H. N. Zhang, J. Tang, Y. X. Wang, F.
Zhu*. Advances in
current diabetes proteomics: from the perspectives of label-free
quantification and biomarker selection.
Current Drug
Targets
(impact factor of the publication year: 2.6, 医学三区期刊). 21(1): 34-54 (2020). PMID: 31433754.
-
Y. Zhang,
T. T. Fu, Y. X. Ren, F. C. Li, G. X. Zheng, X. J. Yao, W. W. Xue*,
F. Zhu*. Selective
inhibition of HDAC1 by macrocyclic polypeptide for the treatment of
glioblastoma: a binding mechanistic analysis based on molecular
dynamics.
Frontiers in
Molecular Biosciences
(impact factor of the publication year: 3.6, 生物三区期刊). 7: 41 (2020). PMID: 32219100.
-
C. Shen, Z.
Wang, X. J. Yao, T. L. Lei, E. C. Wang, Z. Y. Tian, F. Zhu,
D. Li, T. J. Hou*. Comprehensive assessment of nine docking programs
on type II kinase inhibitors: prediction accuracy of sampling power,
scoring power and screening power.
Briefings in
Bioinformatics
(impact factor of the publication year: 11.6, 生物一区
TOP 期刊). 21(1): 282-297 (2020). PMID: 30379986.
Publications of Year 2019 (click
to show or hide the details)
-
J. Tang, J. B.
Fu, Y. X. Wang, Y. C. Luo, Q. X. Yang, B. Li, G. Tu, J. J. Hong, X. J.
Cui, Y. Z. Chen, L. X. Yao, W. W. Xue, F. Zhu*. Simultaneous
improvement in the precision, accuracy and robustness of label-free
proteome quantification by optimizing data manipulation chains.
Molecular & Cellular
Proteomics
(impact
factor of the publication year: 7.4, 生物一区 TOP
期刊). 18(8): 1683-1699 (2019). PMID: 31097671.
ESI Highly Cited Paper:
-
The Percentile in Subject Area shown in
InCites™
was 0.87% in 2023.
-
The Percentile in Subject Area shown in
InCites™
was 1.12% in 2022.
-
The Percentile in Subject Area shown in
InCites™
was 0.81% in 2021.
-
The Percentile in Subject Area shown in
InCites™
was 0.57% in 2020.
-
Q. X. Yang,
Y. X. Wang, F. C. Li, S. Zhang, Y. C. Luo, Y. Li, J. Tang, B. Li, Y.
Z. Chen, W. W. Xue, F. Zhu*. Identification of
the gene signature reflecting schizophrenia's etiology by
constructing artificial intelligence-based method of enhanced
reproducibility.
CNS Neuroscience
& Therapeutics
(impact factor of the publication year: 7.0,
医学一区 TOP 期刊). 25(9): 1054-1063 (2019). PMID: 31350824.
Cover Article:
-
The
Cover Article
of CNS Neurosci Ther 2019 25(9), Download the Cover
.
-
Y. Zhang,
J. B. Ying, J. J. Hong, F. C. Li, T. T. Fu, F. Y. Yang, G. X. Zheng,
X. J. Yao, Y. Lou, Y. Q. Qiu, W. W. Xue*, F. Zhu*. How does chirality
determine the selective inhibition of histone deacetylase 6? A
lesson from Trichostatin A enantiomers based on molecular dynamics.
ACS Chemical
Neuroscience
(impact factor of the publication year: 4.2,
化学二区 TOP 期刊). 10(5): 2467-2480 (2019). PMID: 30784262.
ESI Highly Cited Paper:
-
The Percentile in Subject Area shown in
InCites™
was 0.48% in 2023.
-
The Percentile in Subject Area shown in
InCites™
was 1.85% in 2022.
-
The Percentile in Subject Area shown in
InCites™
was 1.19% in 2021.
-
The Percentile in Subject Area shown in
InCites™
was 0.74% in 2020.
Cover Article:
-
The
Cover Article
of ACS Chem Neurosci 2019 10(5), Download the Cover
.
-
Z. J. Han,
J. Hua, W. W. Xue, F. Zhu*. Integrating the
ribonucleic acid sequencing data from various studies for exploring
the multiple sclerosis-related long noncoding ribonucleic acids and
their functions.
Frontiers in
Genetics
(impact factor of the publication year: 4.2,
生物二区期刊). 10: 1136 (2019). PMID: 31781177.
-
X. J. Cui,
Q. X. Yang, B. Li, J. Tang, X. Y. Zhang, S. Li, F. C. Li, J. Hu*, Y.
Lou, Y. Q. Qiu, W. W. Xue, F. Zhu*. Assessing the
effectiveness of direct data merging strategy in long-term and
large-scale pharmacometabonomics.
Frontiers in
Pharmacology
(impact factor of the publication year: 3.8,
医学二区期刊). 10: 127 (2019). PMID: 30842738.
-
Z. J. Han,
W. W. Xue, L. Tao, F. Zhu*. Identification of
key lncRNAs in the pathology of Alzheimer’s disease and their
functions based on the GWAS, microarray and RNA-seq data.
Journal of
Alzheimer's Disease
(impact factor of the publication year: 3.8,
医学二区期刊). 68(1): 339-355 (2019). PMID: 30776002.
-
Q. X. Yang,
Y. X. Wang, S. Zhang, J. Tang, F. C. Li, J. Y. Yin, Y. Li, J. B. Fu,
B. Li, W. W. Xue*, F. Zhu*. Biomarker
discovery for immunotherapy of pituitary adenomas: enhanced
robustness and prediction ability by modern computational tools.
International
Journal of Molecular Sciences
(impact factor of the publication year: 4.2, 化学三区期刊). 20(1): 151 (2019). PMID: 30609812.
-
X. F. Li,
X. X. Li, Y. H. Li, C. Y. Yu, W. W. Xue, J. Hu*, B. Li, P. P. Wang,
F. Zhu*. What makes species
productive of anti-cancer drugs? Clues from drugs' species origin,
druglikeness, target and pathway.
Anti-Cancer
Agents in Medicinal Chemistry
(impact factor of the publication year: 2.6, 医学三区期刊). 19(2): 194-203 (2019). PMID: 30370862.
-
J. Tang, Y.
X. Wang, Y. Li, Y. Zhang, R. Y. Zhang, Z. Y. Xiao, Y. C. Luo, X. Y.
Guo, L. Tao, Y. Lou, W. W. Xue, F. Zhu*. Recent
technological advances in the mass spectrometry-based nanomedicine
studies: an insight from nanoproteomics.
Current
Pharmaceutical Design
(impact factor of the publication year: 2.8, 医学三区期刊). 25(13): 1536-1553 (2019). PMID: 31258068.
-
X. Ding, K.
X. Fan, J. T. Hu, Z. L. Zang, S. L. Zhang, Y. Zhang, Z. C. Lin, X.
D. Pei, X. Zheng, F. Zhu, H. Yang*, S. Li*. SCP2-mediated
cholesterol membrane trafficking promotes the growth of pituitary
adenomas via Hedgehog signaling activation.
Journal of
Experimental & Clinical Cancer Research
(impact factor of the publication year: 5.6, 医学二区期刊). 38(1): 404 (2019). PMID: 31519191.
-
G. Q. Weng,
E. C. Wang, Z. Wang, H. Liu, F. Zhu, D. Li, T. J. Hou*.
HawkDock: a web server to predict and analyze the protein-protein
complex based on computational docking and MM/GBSA.
Nucleic Acids
Research
(impact factor of the publication year: 11.6, 生物一区
TOP 期刊). 47(W1): 322-330 (2019). PMID: 31106357.
ESI Highly Cited Paper:
-
The Percentile in Subject Area shown in
InCites™
was 0.53% in 2023.
-
Z. Wang, X.
W. Wang, Y. Y. Li, T. L. Lei, E. C. Wang, D. Li, Y. Kang, F.
Zhu, T. J. Hou*. farPPI: a webserver for accurate prediction
of protein-ligand binding structures for small-molecule PPI
inhibitors by MM/PB(GB)SA methods.
Bioinformatics
(impact factor of the publication year: 5.5, 生物二区 TOP
期刊). 35(10): 1777-1779 (2019). PMID: 30329012.
-
H. Y. Chen,
W. T. Fu, Z. Wang, X. W. Wang, T. L. Lei, F. Zhu, D. Li, S.
Chang, L. Xu, T. J. Hou*. Reliability of docking-based virtual
screening for GPCR ligands with homology modeled structures: a case
study of angiotensin II type I receptor.
ACS Chemical
Neuroscience
(impact factor of the publication year: 4.2, 化学二区 TOP
期刊). 10(1): 677-689 (2019). PMID: 30265513.
-
T. L. Xie,
J. Yu, W. T. Fu, Z. Wang, L. Xu, S. Chang, E. C. Wang, F.
Zhu, S. Zeng, Y. Kang, T. J. Hou*. Insight into the
selective binding mechanism of DNMT1 and DNMT3A inhibitors: a
molecular simulation study.
Physical
Chemistry Chemical Physics
(impact factor of the publication year: 4.1, 化学二区 TOP
期刊). 21(24): 12931-12947 (2019). PMID: 31165133.
-
E. C. Wang,
G. Q. Weng, H. Y. Sun, H. Y. Du, F. Zhu, F. Chen, Z. Wang, T.
J. Hou*. Assessing the performance of the MM/PBSA and MM/GBSA
methods. 10. Impacts of enhanced sampling and variable dielectric
model on protein-protein interactions.
Physical
Chemistry Chemical Physics
(impact factor of the publication year: 4.1, 化学二区 TOP
期刊). 21(35): 18958-18969 (2019). PMID: 31453590.
Publications of Year 2018 (click
to show or hide the details)
-
Y. H. Li, C. Y. Yu,
X. X. Li, P. Zhang, J. Tang, Q. X. Yang, T. T. Fu, X. Y. Zhang, X. J. Cui,
G. Tu, Y. Zhang, S. Li, F. Y. Yang, Q. Sun, C. Qin, X. Zeng, Z. Chen, Y. Z.
Chen*, F. Zhu*. Therapeutic target
database update 2018: enriched resource for facilitating bench-to-clinic
research of targeted therapeutics.
Nucleic Acids Research
(impact
factor of the publication year: 11.6, 生物一区 TOP
期刊). 46(D1): 1121-1127 (2018). PMID: 29140520.
ESI Highly Cited Paper:
-
The Percentile in Subject Area shown in
InCites™
was 0.28% in 2023.
-
The Percentile in Subject Area shown in
InCites™
was 0.21% in 2022.
-
The Percentile in Subject Area shown in
InCites™
was 0.15% in 2021.
-
The Percentile in Subject Area shown in
InCites™
was 0.14% in 2020.
-
The Percentile in Subject Area shown in
InCites™
was 0.16% in 2019.
Highlights by Experts in Subject Area:
-
Introduced by
OMICTOOLS
as "useful for facilitating patient focused research,
discovery and clinical investigations of the targeted
therapeutics".
-
J. B. Fu, J.
Tang, Y. X. Wang, X. J. Cui, Q. X. Yang, J. J. Hong, X. X. Li, S. Li, Y.
Z. Chen, W. W. Xue, F. Zhu*. Discovery of the
consistently well-performed analysis chain for SWATH-MS based
pharmacoproteomic quantification.
Frontiers in
Pharmacology
(impact
factor of the publication year: 4.4, 医学二区期刊). 9: 681 (2018). PMID: 29997509.
ESI Highly Cited Paper:
-
The Percentile in Subject Area shown in
InCites™
was 1.46% in
2022.
-
The Percentile in Subject Area shown in
InCites™
was 0.99% in
2021.
-
The Percentile in Subject Area shown in
InCites™
was 0.85% in
2020.
-
The Percentile in Subject Area shown in
InCites™
was 0.78% in
2019.
-
F. Zhu*, X. X. Li, S. Y. Yang,
Y. Z. Chen*. Clinical success of drug targets prospectively predicted by
in-silico study.
Trends in
Pharmacological Sciences
(impact
factor of the publication year: 12.8, 医学一区 TOP
期刊). 39(3): 229-231 (2018). PMID: 29295742.
ESI Highly Cited Paper:
-
The Percentile in Subject Area shown in
InCites™
was 0.30% in 2023.
-
The Percentile in Subject Area shown in
InCites™
was 0.84% in 2022.
-
The Percentile in Subject Area shown in
InCites™
was 0.38% in 2021.
-
The Percentile in Subject Area shown in
InCites™
was 0.34% in 2020.
-
The Percentile in Subject Area shown in
InCites™
was 0.10% in 2019.
-
Z. J. Han, W.
W. Xue, L. Tao, F. Zhu*. Identification of
novel immune-relevant drug target genes for alzheimer's disease by
combining ontology inference with network analysis.
CNS Neuroscience &
Therapeutics
(impact
factor of the publication year: 7.0, 医学一区 TOP
期刊). 24(12): 1253-1263 (2018). PMID: 30106219.
Honors and Awards:
-
Wiley Top Cited Paper Award (2020).
Cover Article:
-
The
Cover Article
of CNS Neurosci Ther 2018 24(12), Download the Cover
.
-
F. Y. Yang, G.
X. Zheng, T. T. Fu, X. F. Li, G. Tu, Y. H. Li, X. J. Yao, W. W. Xue*,
F. Zhu*. Prediction of binding
mode and resistance profile for dual-target pyrrolyl diketo acid
scaffold against HIV-1 integrase and reverse-transcriptase associated
ribonuclease H.
Physical Chemistry
Chemical Physics
(impact
factor of the publication year: 4.1, 化学二区 TOP
期刊). 20(37): 23873-23884 (2018). PMID: 29947629.
Back Cover Article:
-
X. X. Li, J. Y.
Yin, J. Tang, Y. H. Li, Q. X. Yang, Z. Y. Xiao, R. Y. Zhang, Y. X. Wang,
J. J. Hong, L. Tao, W. W. Xue, F. Zhu*. Determining the
balance between drug efficacy and safety by the network and biological
system profile of its therapeutic target.
Frontiers in
Pharmacology
(impact
factor of the publication year: 4.4, 医学二区期刊). 9: 1245 (2018). PMID: 30429792.
-
T. T. Fu, G. X.
Zheng, G. Tu, F. Y. Yang, Y. Z. Chen, X. J. Yao, X. F. Li, W. W. Xue*,
F. Zhu*. Exploring the binding
mechanism of metabotropic glutamate receptor 5 negative allosteric
modulators in clinical trials by molecular dynamics simulations.
ACS Chemical
Neuroscience
(impact
factor of the publication year: 4.2, 化学二区 TOP
期刊). 9(6): 1492-1502 (2018). PMID: 29522307.
ESI Highly Cited Paper:
-
The Percentile in Subject Area shown in
InCites™
was 0.54% in
2023.
-
The Percentile in Subject Area shown in
InCites™
was 1.35% in
2022.
-
The Percentile in Subject Area shown in
InCites™
was 0.72% in
2021.
-
The Percentile in Subject Area shown in
InCites™
was 0.78% in
2020.
-
W. W. Xue, P.
P. Wang, G. Tu, F. Y. Yang, G. X. Zheng, X. F. Li, X. X. Li, Y. Z. Chen,
X. J. Yao, F. Zhu*. Computational
identification of the binding mechanism of triple reuptake inhibitor
amitifadine for the treatment of major depressive disorder.
Physical Chemistry
Chemical Physics
(impact
factor of the publication year: 4.1, 化学二区 TOP
期刊). 20(9): 6606-6616 (2018). PMID: 29451287.
ESI Highly Cited Paper:
-
The Percentile in Subject Area shown in
InCites™
was 0.83% in 2023.
-
The Percentile in Subject Area shown in
InCites™
was 1.95% in 2022.
-
The Percentile in Subject Area shown in
InCites™
was 1.46% in 2021.
-
The Percentile in Subject Area shown in
InCites™
was 1.47% in 2020.
-
W. W. Xue, F.
Y. Yang, P. P. Wang, G. X. Zheng, Y. Z. Chen, X. J. Yao, F. Zhu*. What contributes to
serotonin-norepinephrine reuptake inhibitors' dual-targeting mechanism?
The key role of transmembrane domain 6 in human serotonin and
norepinephrine transporters revealed by molecular dynamics simulation.
ACS Chemical
Neuroscience
(impact
factor of the publication year: 4.2, 化学二区 TOP
期刊). 9(5): 1128-1140 (2018). PMID: 29300091.
ESI Highly Cited Paper:
-
The Percentile in Subject Area shown in
InCites™
was 0.11% in
2023.
-
The Percentile in Subject Area shown in
InCites™
was 0.18% in
2022.
-
The Percentile in Subject Area shown in
InCites™
was 0.14% in
2021.
-
The Percentile in Subject Area shown in
InCites™
was 0.21% in
2020.
-
The Percentile in Subject Area shown in
InCites™
was 0.29% in
2019.
-
G. X. Zheng, F.
Y. Yang, T. T. Fu, G. Tu, Y. Z. Chen, X. J. Yao, W. W. Xue*, F.
Zhu*. Computational
characterization of the selective inhibition of human norepinephrine and
serotonin transporters by escitalopram scaffold.
Physical Chemistry
Chemical Physics
(impact
factor of the publication year: 4.1, 化学二区 TOP
期刊). 20(46): 29513-29527 (2018). PMID: 30457616.
-
C. Y. Yu, X. X.
Li, H. Yang, Y. H. Li, W. W. Xue, Y. Z. Chen, L. Tao, F. Zhu*. Assessing the
performances of protein function prediction algorithms from the
perspectives of identification accuracy and false discovery rate.
International Journal
of Molecular Sciences
(impact
factor of the publication year: 3.7, 化学三区期刊). 19(1): 183 (2018). PMID: 29316706.
-
G. Tu, T. T.
Fu, F. Y. Yang, L. X. Yao, W. W. Xue*, F. Zhu*. Prediction of
GluN2B-CT1290-1310/DAPK1 interaction by protein-peptide docking and
molecular dynamics simulation.
Molecules
(impact
factor of the publication year: 3.1, 化学三区期刊). 23(11): 3018 (2018). PMID: 30463177.
-
J. Tang, Y.
Zhang, J. B. Fu, Y. X. Wang, Y. Li, Q. X. Yang, L. X. Yao, W. W. Xue*,
F. Zhu*. Computational advances
in the label-free quantification of cancer proteomics data.
Current
Pharmaceutical Design
(impact
factor of the publication year: 2.8, 医学三区期刊). 24(32): 3842-3858 (2018). PMID: 30387388.
-
P. C. Pan, J.
Chen, X. J. Li, M. Y. Li, H. D. Yu, J. Zhao, J. Ni, X. W. Wang, H. Y.
Sun, S. Tian, F. Zhu, F. Liu, Y. Huang, T. J. Hou*.
Structure-based drug design and identification of H2O-soluble and low
toxic hexacyclic camptothecin derivatives with improved efficacy in
cancer and lethal inflammation models in vivo.
Journal of Medicinal
Chemistry
(impact
factor of the publication year: 6.3, 医学二区 TOP 期刊). 61(19): 8613-8624 (2018). PMID: 30227711.
-
F. Chen, H. Y.
Sun, J. M. Wang, F. Zhu, H. Liu, Z. Wang, T. L. Lei, Y. Y. Li, T.
J. Hou*. Assessing the performance of MM/PBSA and MM/GBSA methods. 8.
Predicting binding free energies and poses of protein-RNA complexes.
RNA
(impact
factor of the publication year: 4.6, 生物二区期刊). 24(9): 1183-1194 (2018). PMID: 29930024.
-
J. Shang, B.
Hu, J. M. Wang, F. Zhu, Y. Kang, D. Li, H. Y. Sun, D. X. Kong, T.
J. Hou*. Cheminformatic insight into the differences between terrestrial
and marine originated natural products.
Journal of Chemical
Information and Modeling
(impact
factor of the publication year: 3.8, 化学二区期刊). 58(6): 1182-1193 (2018). PMID: 29792805.
-
H. Y. Sun, F.
Chen, H. Liu, Z. Wang, P. C. Chen, F. Zhu, T. J. Hou*. Assessing
the performance of MM/PBSA and MM/GBSA methods. 7. Entropy effects on
the performance of end-point binding free energy calculation approaches.
Physical Chemistry
Chemical Physics
(impact
factor of the publication year: 4.1, 化学二区 TOP 期刊). 20(21): 14450-14460 (2018). PMID: 29785435.
ESI Highly Cited Paper:
-
The Percentile in Subject Area shown in
InCites™
was 0.18% in
2023.
-
X. T. Kong, H.
Y. Sun, P. C. Pan, F. Zhu, S. Chang, L. Xu, Y. Y. Li, T. J. Hou*.
Importance of protein flexibility on molecular recognition: a case study
on type-I1/2 inhibitors of ALK.
Physical Chemistry
Chemical Physics
(impact
factor of the publication year: 4.1, 化学二区 TOP 期刊). 20(7): 4851-4863 (2018). PMID: 29383359.
Publications of Year 2017 (click
to show or hide the details)
-
B. Li, J. Tang, Q.
X. Yang, S. Li, X. J. Cui, Y. H. Li, Y. Z. Chen, W. W. Xue, X. F. Li, F.
Zhu*. NOREVA: normalization and
evaluation of MS-based metabolomics data.
Nucleic Acids Research
(impact
factor of the publication year: 10.2, 生物一区 TOP
期刊). 45(W1): 162-170 (2017). PMID: 28525573.
ESI Highly Cited Paper:
-
The Percentile in Subject Area shown in
InCites™
was 0.60% in 2023.
-
The Percentile in Subject Area shown in
InCites™
was 0.77% in 2022.
-
The Percentile in Subject Area shown in
InCites™
was 0.71% in 2021.
-
The Percentile in Subject Area shown in
InCites™
was 0.75% in 2020.
-
The Percentile in Subject Area shown in
InCites™
was 1.27% in 2019.
-
The Percentile in Subject Area shown in
InCites™
was 2.98% in 2018.
Highlights by Experts in Subject Area:
-
Introduced by
OMICTOOLS
as "provided valuable guidance to the selection of
suitable algorithm in metabolomics".
-
Discussed in
StackExchange
as "works fine" and "corrections for batches
without QC options".
-
P. P. Wang, X.
Y. Zhang, T. T. Fu, S. Li, B. Li, W. W. Xue*, X. J. Yao, Y. Z. Chen,
F. Zhu*. Differentiating
physicochemical properties between addictive and nonaddictive ADHD drugs
revealed by molecular dynamics simulation studies.
ACS Chemical
Neuroscience
(impact
factor of the publication year: 4.3, 化学二区 TOP
期刊). 8(6): 1416-1428 (2017). PMID: 28557437.
ESI Highly Cited Paper:
-
The Percentile in Subject Area shown in
InCites™
was 2.17% in 2022.
-
The Percentile in Subject Area shown in
InCites™
was 1.48% in 2021.
-
The Percentile in Subject Area shown in
InCites™
was 1.80% in 2020.
-
The Percentile in Subject Area shown in
InCites™
was 1.32% in 2019.
-
G. X. Zheng, W.
W. Xue*, F. Y. Yang, Y. Zhang, Y. Z. Chen, X. J. Yao, F. Zhu*. Revealing vilazodone's
binding mechanism underlying its partial agonism to 5-HT1A receptor in
the treatment of major depressive disorder.
Physical Chemistry
Chemical Physics
(impact
factor of the publication year: 4.4, 化学二区 TOP
期刊). 19(42): 28885-28896 (2017). PMID: 29057413.
ESI Highly Cited Paper:
-
The Percentile in Subject Area shown in
InCites™
was 1.47% in 2020.
-
P. P. Wang, T.
T. Fu, X. Y. Zhang, F. Y. Yang, G. X. Zheng, W. W. Xue*, Y. Z. Chen, X.
J. Yao, F. Zhu*. Differentiating
physicochemical properties between NDRIs and sNRIs clinically important
for the treatment of ADHD.
Biochimica et
Biophysica Acta - General Subjects
(impact
factor of the publication year: 5.1, 生物二区期刊). 1861(11A): 2766-2777 (2017). PMID: 28757337.
-
P. C. Pan, H.
D. Yu, Q. L. Liu, X. T. Kong, H. Chen, J. A. Chen, Q. Liu, D. Li, Y.
Kang, H. Y. Sun, W. F. Zhou, S. Tian, S. L. Cui, F. Zhu, Y. Y.
Li, Y. Huang, T. J. Hou*. Combating drug-resistant mutants of ALK with
potent and selective type-I1/2 inhibitors by stabilizing unique
DFG-shifted loop conformation.
ACS Central Science
(impact
factor of the publication year: 7.9, 化学一区 TOP 期刊). 3(11): 1208-1220 (2017). PMID: 29202023.
-
T. Feng, F.
Chen, Y. Kang, H. Y. Sun, H. Liu, D. Li, F. Zhu, T. J. Hou*.
HawkRank: a new scoring function for protein-protein docking based on
weighted energy terms.
Journal of
Cheminformatics
(impact
factor of the publication year: 4.2, 化学二区 TOP 期刊). 9(1): 66 (2017). PMID: 29282565.
-
T. L. Lei, H.
Y. Sun, Y. Kang, F. Zhu, H. Liu, W. F. Zhou, Z. Wang, D. Li, Y.
Y. Li, T. J. Hou*. ADMET evaluation in drug discovery. 18. Reliable
prediction of chemical-induced urinary tract toxicity by boosting
machine learning approaches.
Molecular
Pharmaceutics
(impact
factor of the publication year: 4.4, 医学二区期刊). 14(11): 3935-3953 (2017). PMID: 29037046.
-
S. Tian, X.
Wang, L. L. Li, X. H. Zhang, Y. Y. Li, F. Zhu, T. J. Hou*, X. C.
Zhen*. Discovery of novel and selective adenosine A2A receptor
antagonists for treating parkinson's disease through comparative
structure-based virtual screening.
Journal of Chemical
Information and Modeling
(impact
factor of the publication year: 3.8, 化学二区期刊). 57(6): 1474-1487 (2017). PMID: 28463561.
-
X. T. Kong, H.
Y. Sun, P. C. Pan, D. Li, F. Zhu, S. Chang, L. Xu, Y. Y. Li*, T.
J. Hou*. How does the L884P mutation confer resistance to type-II
inhibitors of JAK2 kinase: a comprehensive molecular modeling study.
Scientific Reports
(impact
factor of the publication year: 4.3, 综合性三区期刊). 7(1): 9088 (2017). PMID: 28831147.
-
J. Y. An, X. D.
Pei, Z. L. Zang, Z. Zhou, J. T. Hu, X. Zheng, Y. Zhang, J. J. He, L.
Duan, R. F. Shen, W. H. Zhang, F. Zhu, S. Li*, H. Yang*.
Metformin inhibits proliferation and growth hormone secretion of GH3
pituitary adenoma cells.
Oncotarget
(impact
factor of the publication year: 5.2, 医学二区期刊). 8(23): 37538-37549 (2017). PMID: 28380462.
-
P. Zhang, L.
Tao, X. Zeng, C. Qin, S. Y. Chen, F. Zhu, Z. R. Li, Y. Y. Jiang,
W. P. Chen, Y. Z. Chen*. A protein network descriptor server and its use
in studying protein, disease, metabolic and drug targeted networks.
Briefings in
Bioinformatics
(impact
factor of the publication year: 8.4, 生物一区 TOP 期刊). 18(6): 1057-1070 (2017). PMID: 27542402.
-
P. Zhang, L.
Tao, X. Zeng, C. Qin, S. Y. Chen, F. Zhu, S. Y. Yang, Z. R. Li,
W. P. Chen, Y. Z. Chen*. PROFEAT update: a protein features web-server
with added facility to compute network descriptors for studying
omics-derived networks.
Journal of Molecular
Biology
(impact
factor of the publication year: 4.6, 生物二区 TOP 期刊). 429(3): 416-425 (2017). PMID: 27742592.
Publications of Year 2016 (click
to show or hide the details)
-
H. Yang, C. Qin, Y.
H. Li, L. Tao, J. Zhou, C. Y. Yu, F. Xu, Z. Chen, F. Zhu*, Y. Z. Chen*. Therapeutic
target database update 2016: enriched resource for bench to clinical drug
target and targeted pathway information.
Nucleic Acids Research
(impact
factor of the publication year: 9.2, 生物一区 TOP
期刊). 44(D1): 1069-1074 (2016). PMID: 26578601.
ESI Highly Cited Paper:
-
The Percentile in Subject Area shown in
InCites™
was 0.99% in 2023.
-
The Percentile in Subject Area shown in
InCites™
was 0.99% in 2022.
-
The Percentile in Subject Area shown in
InCites™
was 0.69% in 2021.
-
The Percentile in Subject Area shown in
InCites™
was 0.78% in 2020.
-
The Percentile in Subject Area shown in
InCites™
was 0.66% in 2019.
-
The Percentile in Subject Area shown in
InCites™
was 0.71% in 2018.
-
The Percentile in Subject Area shown in
InCites™
was 0.87% in 2017.
-
B. Li, J. Tang,
Q. X. Yang, X. J. Cui, S. Li, S. J. Chen, Q. X. Cao, W. W. Xue, N. Chen,
F. Zhu*. Performance evaluation
and online realization of data-driven normalization methods used in
LC/MS based untargeted metabolomics analysis.
Scientific Reports
(impact
factor of the publication year: 5.2, 综合性二区期刊). 6: 38881 (2016). PMID: 27958387.
ESI Highly Cited Paper:
-
The Percentile in Subject Area shown in
InCites™
was 2.25% in 2022.
-
The Percentile in Subject Area shown in
InCites™
was 1.83% in 2021.
-
The Percentile in Subject Area shown in
InCites™
was 1.87% in 2020.
-
The Percentile in Subject Area shown in
InCites™
was 2.05% in 2019.
-
W. W. Xue, P.
P. Wang, B. Li, Y. H. Li, X. F. Xu, F. Y. Yang, X. J. Yao, Y. Z. Chen,
F. Xu*, F. Zhu*. Identification of the
inhibitory mechanism of FDA approved selective serotonin reuptake
inhibitors: an insight from molecular dynamics simulation study.
Physical Chemistry
Chemical Physics
(impact
factor of the publication year: 4.5, 化学二区 TOP
期刊). 18(4): 3260-3271 (2016). PMID: 26745505.
Successful Validation of the Constructed Model
:
-
The cocrystallized structure published (Nature.
532(7599):334-9, 2016) right after our publication was highly consistent with the
drug-target binding mode discovered in this study.
-
G. X. Zheng, W.
W. Xue*, P. P. Wang, F. Y. Yang, B. Li, X. F. Li, Y. H. Li, X. J. Yao,
F. Zhu*. Exploring the
inhibitory mechanism of approved selective norepinephrine reuptake
inhibitors and reboxetine enantiomers by molecular dynamics study.
Scientific Reports
(impact
factor of the publication year: 5.2, 综合性二区期刊). 6: 26883 (2016). PMID: 27230580.
-
Y. H. Li, P. P.
Wang, X. X. Li, C. Y. Yu, H. Yang, J. Zhou, W. W. Xue, J. Tan, F.
Zhu*. The human kinome
targeted by FDA approved multi-target drugs and combination products: a
comparative study from the drug-target interaction network perspective.
PLoS ONE
(impact
factor of the publication year: 3.2, 生物三区期刊). 11(11): e0165737 (2016). PMID: 27828998.
-
J. Y. Xu, P. P.
Wang, H. Yang, J. Zhou, Y. H. Li, X. X. Li, W. W. Xue*, C. Y. Yu, Y. B.
Tian, F. Zhu*. Comparison of FDA
approved kinase targets to clinical trial ones: insights from their
system profiles and drug-target interaction networks.
BioMed Research
International
(impact
factor of the publication year: 2.5, 生物三区期刊). 2016: 2509385 (2016). PMID: 27547755.
-
Y. H. Li, J. Y.
Xu, L. Tao, X. F. Li, S. Li, X. Zeng, S. Y. Chen, P. Zhang, C. Qin, C.
Zhang, Z. Chen, F. Zhu*, Y. Z. Chen. SVM-Prot
2016: a web-server for machine learning prediction of protein functional
families from sequence irrespective of similarity.
PLoS ONE
(impact
factor of the publication year: 3.2, 生物三区期刊). 11(8): e0155290 (2016). PMID: 27525735.
ESI Highly Cited Paper:
-
The Percentile in Subject Area shown in
InCites™
was 1.67% in 2022.
-
The Percentile in Subject Area shown in
InCites™
was 1.31% in 2021.
-
The Percentile in Subject Area shown in
InCites™
was 1.41% in 2020.
-
X. Zheng, S.
Li, Z. L. Zang, J. T. Hu, J. Y. An, X. D. Pei, F. Zhu, W. H.
Zhang*, H. Yang*. Evidence for possible role of toll-like receptor 3
mediating virus-induced progression of pituitary adenomas.
Molecular and
Cellular Endocrinology
(impact
factor of the publication year: 3.8, 医学二区期刊). 426: 22-32 (2016). PMID: 26891958.
Publications before Year 2016 (click to show or hide the details)
-
L. Tao&,
F. Zhu&, F. Xu, Z. Chen, Y. Y. Jiang*, Y. Z. Chen*.
Co-targeting cancer drug escape pathways confers clinical advantage for
multi-target anticancer drugs.
Pharmacological Research
(impact
factor of the publication year: 4.8, 医学二区期刊). 102: 123-131 (2015). PMID: 26438971.
-
L. Tao, P.
Zhang, C. Qin, S. Y. Chen, C. Zhang, Z. Chen, F. Zhu, S. Y. Yang,
Y. Q. Wei, Y. Z. Chen*. Recent progresses in the exploration of machine
learning methods as in-silico ADME prediction tools.
Advanced Drug
Delivery Reviews
(impact
factor of the publication year: 15.6, 医学一区 TOP 期刊). 86: 83-100 (2015). PMID: 26037068.
-
L. Tao, F.
Zhu, C. Qin, C. Zhang, S. Y. Chen, P. Zhang, C. L. Zhang, C. Y.
Tan, C. M. Gao, Z. Chen, Y. Y. Jiang*, Y. Z. Chen*. Clustered
distribution of natural product leads of drugs in the chemical space as
influenced by the privileged target-sites.
Scientific Reports
(impact
factor of the publication year: 5.6, 综合性二区期刊). 5: 9325 (2015). PMID: 25790752.
-
P. P. Wang, F.
Y. Yang, H. Yang, X. F. Xu, D. Liu, W. W. Xue, F. Zhu*. Identification of dual
active agents targeting 5-HT1A and SERT by combinatorial virtual
screening methods.
Bio-Medical Materials
and Engineering
(impact
factor of the publication year: 1.1, 工程技术四区期刊). 26(S1): 2233-2239 (2015). PMID: 26406003.
-
L. Tao, F.
Zhu, C. Qin, C. Zhang, F. Xu, C. Y. Tan, Y. Y. Jiang*, Y. Z. Chen*.
Nature's contribution to today's pharmacopeia.
Nature Biotechnology
(impact
factor of the publication year: 32.4, 工程技术一区 TOP
期刊). 32(10): 979-980 (2014). PMID: 25299914.
-
C. Zhang, C.
Qin, L. Tao, F. Zhu, S. Y. Chen, P. Zhang, S. Y. Yang, Y. Q. Wei,
Y. Z. Chen*. A resource for facilitating the development of tools in the
education and implementation of genomics-informed personalized medicine.
Clinical Pharmacology
& Therapeutics
(impact
factor of the publication year: 7.4, 医学一区 TOP 期刊). 95(6): 590-591 (2014). PMID: 24556782.
-
C. Qin, C.
Zhang, F. Zhu, F. Xu, S. Y. Chen, P. Zhang, Y. H. Li, S. Y. Yang,
Y. Q. Wei, L. Tao*, Y. Z. Chen*. Therapeutic target database update
2014: a resource for targeted therapeutics.
Nucleic Acids
Research
(impact
factor of the publication year: 8.3, 生物一区 TOP 期刊). 42(D1): 1118-1123 (2014). PMID: 24265219.
ESI Highly Cited Paper:
-
The Percentile in Subject Area shown in
InCites™
was 2.92% in 2018.
-
The Percentile in Subject Area shown in
InCites™
was 1.16% in 2017.
-
X. Liu, F.
Zhu, X. H. Ma, Z. Shi, S. Y. Yang, Y. Q. Wei, Y. Z. Chen*.
Predicting targeted polypharmacology for drug repositioning and
multi-target drug discovery.
Current Medicinal
Chemistry
(impact
factor of the publication year: 4.9, 医学二区期刊). 20(13): 1646-1661 (2013). PMID: 23410165.
-
F. Zhu,
X. H. Ma, C. Qin, L. Tao, X. Liu, Z. Shi, C. L. Zhang, C. Y. Tan, Y. Z.
Chen*, Y. Y. Jiang*. Drug discovery prospect from untapped species:
indications from approved natural product drugs.
PLoS ONE
(impact
factor of the publication year: 4.4, 生物三区期刊). 7(7): e39782 (2012). PMID: 22808057.
-
X. H. Ma, F.
Zhu, X. Liu, Z. Shi, J. X. Zhang, S. Y. Yang, Y. Q. Wei, Y. Z.
Chen*. Virtual screening methods as tools for drug lead discovery from
large chemical libraries.
Current Medicinal
Chemistry
(impact
factor of the publication year: 4.6, 医学二区期刊). 19(32): 5562-5571 (2012). PMID: 23016548.
-
J. X. Zhang, J.
Jia, F. Zhu, X. H. Ma, B. C. Han, X. N. Wei, C. Y. Tan, Y. Y.
Jiang*, Y. Z. Chen*. Analysis of bypass signaling in EGFR pathway and
profiling of bypass genes for predicting response to anticancer EGFR
tyrosine kinase inhibitors.
Molecular BioSystems
(impact
factor of the publication year: 3.8, 生物三区期刊). 8(10): 2645-2656 (2012). PMID: 22833077.
-
F. Zhu,
Z. Shi, C. Qin, L. Tao, X. Liu, F. Xu, L. Zhang, Y. Song, X. H. Liu, J.
X. Zhang, B. C. Han, P. Zhang, Y. Z. Chen*. Therapeutic target database
update 2012: a resource for facilitating target-oriented drug discovery.
Nucleic Acids
Research
(impact
factor of the publication year: 8.0, 生物一区 TOP
期刊). 40(D1): 1128-1136 (2012). PMID: 21948793.
ESI Highly Cited Paper:
-
The Percentile in Subject Area shown in
InCites™
was 0.71% in 2023.
-
The Percentile in Subject Area shown in
InCites™
was 0.77% in 2022.
-
The Percentile in Subject Area shown in
InCites™
was 0.69% in 2021.
-
The Percentile in Subject Area shown in
InCites™
was 0.66% in 2020.
-
The Percentile in Subject Area shown in
InCites™
was 0.60% in 2019.
-
The Percentile in Subject Area shown in
InCites™
was 0.62% in 2018.
-
The Percentile in Subject Area shown in
InCites™
was 0.31% in 2017.
Highlights by Experts in Subject Area:
-
"
FACULTYof1000
" as "the top 2% of published articles in biology and
medicine" and "a most useful resource for scientists and
companies working on drug discovery and validation, drug lead
discovery and optimization, and the development of multi-target
drugs and drug combinations".
-
Prof. Chris Southan
in his blog as "
Therapeutic Target Database in PubChem
".
-
F. Zhu,
C. Qin, L. Tao, X. Liu, Z. Shi, X. H. Ma, J. Jia, Y. Tan, C. Cui, J. S.
Lin, C. Y. Tan, Y. Y. Jiang*, Y. Z. Chen*. Clustered patterns of species
origins of nature-derived drugs and clues for future bioprospecting.
Proceedings
of the National Academy of Sciences of the United States of
America
(impact
factor of the publication year: 9.4, 综合性一区 TOP
期刊). 108(31): 12943-12948 (2011). PMID: 21768386.
ESI Highly Cited Paper:
-
The Percentile in Subject Area shown in
InCites™
was 0.74% in 2023.
-
The Percentile in Subject Area shown in
InCites™
was 0.95% in 2022.
-
The Percentile in Subject Area shown in
InCites™
was 0.98% in 2021.
-
The Percentile in Subject Area shown in
InCites™
was 0.93% in 2020.
-
The Percentile in Subject Area shown in
InCites™
was 0.94% in 2019.
-
The Percentile in Subject Area shown in
InCites™
was 1.16% in 2018.
-
The Percentile in Subject Area shown in
InCites™
was 1.91% in 2017.
Highlights by Experts in Subject Area:
Media Coverage & News Report:
-
NEWS MEDICAL. Sep 8th, 2011.
-
Medical News Today (MNT). Sep 7th, 2011.
-
mediLexicon.com. Sep 7th, 2011.
-
BrightSurf.com. Sep 7th, 2011.
-
SCIENCE CODEX. Sep 6th, 2011.
-
Sciencenewsline biology. Sep 6th, 2011.
-
Medical Xpress. Sep 6th, 2011.
-
First Science News. Sep 6th, 2011.
-
Lab spaces.net. Sep 6th, 2011.
-
Eurek Alert. Sep 6th, 2011.
-
eBioNews. Sep 1st, 2011.
-
Science Daily. Aug 31st, 2011.
-
Health Canal.com. Aug 31st, 2011.
-
News Ecology. Aug 31st, 2011.
-
H. B.
Rao&, F. Zhu&, G. B. Yang, Z. R.
Li*, Y. Z. Chen. Update of PROFEAT: a web server for computing
structural and physicochemical features of proteins and peptides from
amino acid sequence.
Nucleic Acids
Research
(impact
factor of the publication year: 7.8, 生物一区 TOP
期刊). 39(W1): 385-390 (2011). PMID: 21609959.
-
X. Liu, F.
Zhu, X. H. Ma, L. Tao, J. X. Zhang, S. Y. Yang, Y. Q. Wei, Y. Z.
Chen*. The therapeutic target database: an internet resource for the
primary targets of approved, clinical trial and experimental drugs.
Expert Opinion on
Therapeutic Targets
(impact
factor of the publication year: 3.7, 生物二区期刊). 15(8): 903-912 (2011). PMID: 21619487.
-
F. Zhu,
B. C. Han, P. Kumar, X. H. Liu, X. H. Ma, X. N. Wei, L. Huang, Y. F.
Guo, L. Y. Han, C. J. Zheng, Y. Z. Chen*. Update of TTD: therapeutic
target database.
Nucleic Acids
Research
(impact
factor of the publication year: 7.5, 生物一区 TOP
期刊). 38(D1): 787-791 (2010). PMID: 19933260.
ESI Highly Cited Paper:
-
The Percentile in Subject Area shown in
InCites™
was 2.95% in 2017.
-
F. Zhu,
L. Y. Han, C. J. Zheng, B. Xie, M. T. Tammi, S. Y. Yang, Y. Q. Wei, Y.
Z. Chen*. What are next generation innovative therapeutic targets? Clues
from genetic, structural, physicochemical, and systems profiles of
successful targets.
Journal of
Pharmacology and Experimental Therapeutics
(impact
factor of the publication year: 3.9, 医学二区 TOP
期刊). 330(1): 304-315 (2009). PMID: 19357322.
Successful Validation of the Constructed Model:
-
Pasireotide
targeting Somatostatin receptor 1 was approved by FDA
in 2011.
-
Fingolimod
targeting S1P receptor was approved by FDA in 2010.
-
Ecallantide
targeting Plasma Kallikrein was approved by FDA in
2009.
-
Cinryze
targeting C1 esterase was approved by FDA in 2009.
-
Icatibant
targeting BK-2 receptor was approved by FDA in 2008.
-
Plerixafor
targeting CXCR4 was approved by FDA in 2008.
-
J. Jia, F.
Zhu, X. H. Ma, Z. W. Cao, Y. X. Li, Y. Z. Chen*. Mechanisms of
drug combinations: interaction and network perspectives.
Nature Reviews Drug
Discovery
(impact
factor of the publication year: 23.3, 医学一区 TOP
期刊). 8(2): 111-128 (2009). PMID: 19180105.
ESI Highly Cited Paper:
-
The Percentile in Subject Area shown in
InCites™
was 0.73% in 2023.
-
The Percentile in Subject Area shown in
InCites™
was 0.76% in 2022.
-
The Percentile in Subject Area shown in
InCites™
was 0.91% in 2021.
-
The Percentile in Subject Area shown in
InCites™
was 0.97% in 2020.
-
The Percentile in Subject Area shown in
InCites™
was 1.06% in 2019.
-
The Percentile in Subject Area shown in
InCites™
was 1.13% in 2018.
-
The Percentile in Subject Area shown in
InCites™
was 1.39% in 2017.
-
X. H. Ma, J. Jia,
F. Zhu, Y. Xue, Z. R. Li, Y. Z. Chen*. Comparative analysis of
machine learning methods in ligand-based virtual screening of large compound
libraries.
Combinatorial Chemistry &
High Throughput Screening
(impact
factor of the publication year: 2.3, 化学四区期刊). 12(4): 344-357 (2009). PMID: 19442064.
-
F. Zhu,
L. Y. Han, X. Chen, H. H. Lin, S. Ong, B. Xie, H. L. Zhang, Y. Z. Chen*.
Homology-free prediction of functional class of proteins and peptides by
support vector machines.
Current Protein &
Peptide Science
(impact
factor of the publication year: 4.0, 生物三区期刊). 9(1): 70-95 (2008). PMID: 18336324.
-
L. Y. Han, X.
H. Ma, H. H. Lin, J. Jia, F. Zhu, Y. Xue, Z. R. Li, Z. W. Cao, Z.
L. Ji, Y. Z. Chen*. A support vector machines approach for virtual
screening of active compounds of single and multiple mechanisms from
large libraries at an improved hit-rate and enrichment factor.
Journal of Molecular
Graphics & Modelling
(impact
factor of the publication year: 2.4, 生物四区期刊). 26(8): 1276-1286 (2008). PMID: 18218332.
-
L. Y. Han, C.
J. Zheng, B. Xie, J. Jia, X. H. Ma, F. Zhu, H. H. Lin, X. Chen,
Y. Z. Chen*. Support vector machines approach for predicting druggable
proteins: recent progress in its exploration and investigation of its
usefulness.
Drug Discovery Today
(impact
factor of the publication year: 7.8, 药学一区 TOP 期刊). 12(7-8): 304-313 (2007). PMID: 17395090.
-
H. H. Lin, L.
Y. Han, C. W. Yap, Y. Xue, X. H. Liu, F. Zhu, Y. Z. Chen*.
Prediction of factor Xa inhibitors by machine learning methods.
Journal of Molecular
Graphics & Modelling
(impact
factor of the publication year: 2.3, 生物四区期刊). 26(2): 505-518 (2007). PMID: 17418603.
INTERNATIONAL AND
DOMESTIC
CONFERENCES
( news in
photo)
Hosted Conference and Symposium (click to show or hide the details)
-
F. Zhu
is the Chair of the Organizing Committee for
The 4th Worldwide
Chinese Computational Biology Conference.
Zhejiang University, Hangzhou, P. R. China (2022).
-
F.
Zhu is the Member of the Academic Committee for
The 4th Worldwide
Chinese Computational Biology Conference. Zhejiang University, Hangzhou, P. R. China (2022).
-
F.
Zhu is the Chair of the Organizing Committee for
The 11st Asia Hub
for e-Drug Discovery. Zhejiang University, Hangzhou, P. R. China (2021).
-
F.
Zhu is the Member of the Academic Committee for
The 11st Asia Hub
for e-Drug Discovery. Zhejiang University, Hangzhou, P. R. China (2021).
-
F.
Zhu is the Chairman of the Symposium II (chemometrics and
life science) for
The 16th National
Symposium of Computer & Computational Chemistry. Jilin University, Changchun, P. R. China (2021).
-
F.
Zhu is the Member of the Academic Committee for
The 16th National
Symposium of Computer & Computational Chemistry. Jilin University, Changchun, P. R. China (2021).
-
F.
Zhu is the Chairman of the Symposium IV (precision drug
design and precision medicine) for
The 15th National
Symposium of Computer & Computational Chemistry. Fudan University, Shanghai, P. R. China (2019).
-
F.
Zhu is the Member of the Academic Committee for
The 15th National
Symposium of Computer & Computational Chemistry. Fudan University, Shanghai, P. R. China (2019).
-
F.
Zhu is the Chairman of the Symposium II (OMIC big data
and medical application) for
The Fourth CCF
Bioinformatics Conference. South China University of Technology, Guangzhou, P. R. China
(2019).
-
F.
Zhu is the Member of the Academic Committee for
The Fourth CCF
Bioinformatics Conference. South China University of Technology, Guangzhou, P. R. China
(2019).
-
F.
Zhu is the Vice-chairman of the Symposium 24
Session-4 for
The 31st Academic
Annual Conference of the Chinese Chemical Society. Zhejiang University, Hangzhou, P. R. China (2018).
-
F.
Zhu is the Chairman of the Symposium IV Session -7
for
Asian Federation
for Pharmaceutical Sciences Conference 2017. Xiamen University, Xiamen, P. R. China (2017).
-
F.
Zhu is the Member of the Academic Committee for
The 14th National
Symposium of Computer & Computational Chemistry. Nanjing University, Nanjing, P. R. China (2017).
-
F.
Zhu is the Member of the Academic Committee for
The Second CCF
Bioinformatics Conference (CBC-2017). Central South University, Changsha, P. R. China (2017).
-
F. Zhu is the Chairman of the sub-conference
103 (multi-target and protein-protein interaction) for
BIT’s 6th Annual
International Congress of Medichem-2016 (ICM-2016). China Pharmaceutical University, Nanjing, P. R. China (2016).
-
F.
Zhu is the Vice-chairman of the 6th theme (study on drug
transporter and PK/PD) for
BIT’s 6th Annual
International Congress of Medichem-2016 (ICM-2016). China Pharmaceutical University, Nanjing, P. R. China (2016)
-
F.
Zhu is the Chair of the Organizing Committee for
The 2nd Symposium
on Bioinformatics and Drug Design. Chongqing University, Chongqing, P. R. China (2016).
-
F.
Zhu is the Member of the Academic Committee for
The 2nd Symposium
on Bioinformatics and Drug Design. Chongqing University, Chongqing, P. R. China (2016).
-
F.
Zhu is the Member of the Academic Committee for
The 13th National
Symposium of Computer & Computational Chemistry. Sun Yat-sen University, Guangzhou, P. R. China (2015).
-
F.
Zhu is the Member of the Organizing Committee for
International
Symposium on Natural Product Synthesis and Innovative
Process Methods for Drug Manufacture. Chongqing University, Chongqing, P. R. China (2012).
Keynote Speaker of International/Domestic Conference (click to show or hide the details)
-
F.
Zhu*. Artificial
intelligence-based discovery of new drug target. Invited
keynote speaker of domestic conference for
Strategy
Seminar on Chemistry Division of the National Natural
Science Foundation of China & 2021 Annual National
Computational Toxicology Conference of China. Yanan University, Yanan, P. R. China (2021).
-
F.
Zhu*. Promising
target discovery based on multi-omics data. Invited keynote
speaker of domestic conference for
2020 Annual
Conference of Digitization in Medical Administration and
Artificial Intelligence in Drug Discovery. Zhejiang Medical Association, Hangzhou, P. R. China
(2020).
-
F.
Zhu*. Processing of
metabolomic data using NOREVA. Invited keynote speaker of
domestic conference for
2020 Annal
Symposium on Translational Medicine, Bioinformatics and
Genomics/Proteomics/Metabolomics-based Technology. Chongqing Medical University, Chongqing, P. R. China
(2020).
-
F.
Zhu*. Therapeutic
target discovery based on artificial intelligence. Invited
keynote speaker of domestic conference for
2019 Forum of
Intelligent Development of Traditional Chinese Medicine. China Information Association of Traditional Chinese
Medicine, Shanghai, P. R. China (2019).
-
F.
Zhu*. Clinical
target discovery inspired from artificial intelligence.
Invited keynote speaker of domestic conference for
1st West Lake
Clinical Research and Evaluation Conference. The First Affiliated Hospital, Zhejiang University,
Hangzhou, P. R. China (2018).
-
F.
Zhu*. Identification
of key factors indicating the progression timelines of novel
drug targets. Invited keynote speaker of international
conference for
11th
China-Japan Symposium on Molecular Drug Design and
Development. Zhejiang University and Chinese Academy of Medical
Sciences & Peking Union Medical College, Shaoxing, P. R. China
(2018).
-
F.
Zhu*. Identification
of next generation innovative therapeutic target from OMICs
data. Invited keynote speaker
of domestic conference for
2017
Symposium on Pharmaceutical Chemistry of the Yangtze
River Delta Metropolitan Region. Hefei Institute of Physical Science, Chinese Academy of
Sciences, Hefei, P. R. China (2017).
Invited Speaker of International/Domestic Conference (click to show or hide the details)
-
F.
Zhu*.
Progression-speed differentiating features of the innovative
targets of first-in-class drugs. Invited speaker of
international conference for
The
PacifiChem 2021 Symposium. International Chemical Congress of Pacific Basin
Societies, Hawaii, USA (2021).
-
F.
Zhu*. Artificial
intelligence and molecular simulation for accelerating target
discovery. Invited speaker of international conference
for
The
AHeDD2019/IPAB2019 Joint Symposium. Tokyo Institute of Technology, Kawasaki, Japan (2019).
-
F.
Zhu*. AI-based
discovery of innovative therapeutic target. Invited speaker
of domestic conference for
The 15th
National Symposium of Computer & Computational Chemistry. Fudan University, Shanghai, P. R. China (2019).
-
F.
Zhu*. Machine
learning-based discovery of innovative therapeutic target.
Invited speaker of domestic conference for
The 4th China
Analytical Pharmacology Conference. Shenyang Pharmaceutical University, Shenyang, P. R. China
(2019).
-
F.
Zhu*. AI-based
discovery of drug target for HIV infection. Invited speaker
of domestic conference for
Computational
Drug Discovery and ACM Chinese Council. Central South University, Changsha, P. R. China (2019).
-
F.
Zhu*. Therapeutic
target discovery based on artificial intelligence. Invited
speaker of international conference for
2019 Chinese
Medicinal Chemistry Symposium & CPA-EFMC International
Symposium on Medicinal Chemistry. Sichuan University, Chengdu, P. R. China (2019).
-
F.
Zhu*. Simultaneous
improvement in the precision, accuracy and robustness of
label-free proteome quantification by optimizing data
manipulation chains. Invited speaker of international
conference for
The Taizhou
International Conference on Artificial Intelligence and
Biomedical Research. Taizhou University, Taizhou, P. R. China (2019).
-
F.
Zhu*. ANPELA:
analysis and performance-assessment of the label-free
quantification workflow for metaproteomic studies. Invited
speaker of domestic conference for
The 2019
Jiangsu-Zhejiang International Symposium of
Bioinformatics and Computational Sciences. Jiangnan University, Wuxi, P. R. China (2019).
-
F.
Zhu*. Consistent
gene signature of schizophrenia identified by a novel feature
selection strategy from comprehensive sets of transcriptomic
data. Invited speaker of domestic conference for
The 3rd
Conference of Analytical Pharmacology. Zunyi Medical University, Zuiyi, P. R. China (2018).
-
F.
Zhu*. Progression of
first-in-class drugs and their corresponding targets. Invited
speaker of domestic conference for
The 10th
National Symposium of Genetics Society of China. Nanjing Agricultural University, Nanjing, P. R. China
(2018).
-
F.
Zhu*.
Proteomics-directed novel target discovery. Invited speaker
of domestic conference for
The 2018
Annual Symposium of the Shanghai Association of Chinese
Integrative Medicine. Shanghai University of Traditional Chinese Medicine,
Shanghai, P. R. China (2018).
-
F.
Zhu*.
Progression-speed differentiating features of the targets of
first-in-class drugs. Invited speaker of domestic
conference for
The 14th
Symposium of the Chinese Pharmaceutical Association for
Youth Pharmacologist. Chinese Pharmaceutical Association, Hangzhou, P. R. China
(2018).
-
F.
Zhu*. Target
discovery using proteomic and system biological data. Invited
speaker of international conference for
The 2nd
Worldwide Chinese Computational Biology and Molecular
Simulation Conference. Sun Yat-sen University, Guangzhou, P. R. China (2018).
-
F.
Zhu*. OMICs based
innovative drug target discovery. Invited speaker of domestic
conference for
The 31st
Academic Annual Conference of the Chinese Chemical
Society. Zhejiang University, Hangzhou, P. R. China (2018).
-
F.
Zhu*. Next
generation innovative therapeutic target from NOREVA. Invited
speaker of international conference for
Asian
Federation for Pharmaceutical Sciences Conference 2017. Xiamen University, Xiamen, P. R. China (2017).
-
F.
Zhu*. Target
identification assisted by big-data analyzing tools. Invited
speaker of domestic conference for
The 14th
National Symposium of Computer & Computational Chemistry. Nanjing University, Nanjing, P. R. China (2017).
-
F.
Zhu*. Drug design
and big-data platform. Invited speaker of domestic
conference for
The 5th
Academic Forum for Postgraduates. Sichuan University, Chengdu, P. R. China (2017).
-
W. W.
Xue*, F. Zhu*. What
contributes to SNRIs’ dual-targeting mechanism? The key role
played by TM6 domain. Invited speaker of domestic
conference for
The Second
Conference on Innovative Drug Research and Application. Nanjing Biotech and Pharmaceutical Valley, Nanjing, P. R.
China (2017).
-
F.
Zhu*. Normalization
and evaluation of metabolomics and proteomics data from multiple
perspectives. Invited speaker of domestic conference for
Bioinformatics and Intelligent Information Processing
Academic Conference 2017 (BIIP2017). Shanghai Jiao Tong University, Shanghai, P. R. China
(2017).
-
F.
Zhu*. NOREVA:
normalization and evaluation of MS-based metabolomics data.
Invited speaker of domestic conference for
The Fifth
Young Scholars Forum for Interdisciplinary Researches in
Mathematics, Computer Sciences and Biological Sciences. Academy of Mathematics and System Science, Chinese Academy
of Sciences, Beijing, P. R. China (2017).
-
F.
Zhu*. Normalization
and evaluation of MS-based metabolomics data from multiple
perspectives. Invited speaker of domestic conference for
The 2017 (the
second) Conference on Precision and Future Medicine. Zhejiang University, Hangzhou, P. R. China (2017).
-
F.
Zhu*. Large-scale
metabolomics data analysis. Invited speaker of domestic
conference for
China Society
of Biotechnology Young Scientists Forum II. South China University of Technology, Guangzhou, P. R.
China (2017).
-
F.
Zhu*. Bioinformatics
strategies in precision medicine. Invited speaker of
international conference for
The 2016
Symposium of Guanghua Young Distinguished Scholars. Fudan University, Shanghai, P. R. China (2016).
-
F.
Zhu*. Insight into
the pathogenesis of pituitary adenomas by analyzing trans-omic
data. Invited speaker of international conference for
BIT’s 6th
Annual International Congress of Medichem-2016
(ICM-2016). China Pharmaceutical University, Nanjing, P. R. China
(2016).
-
F.
Zhu*. Metabolomics
meta-analysis by MMEASE. Invited speaker of international
conference for
The 1st
International Symposium on Targeted Therapeutics and
Molecular Medicine (ISTTMM 2016). Chongqing University of Arts and Sciences, Chongqing, P.
R. China (2016).
-
W. W.
Xue, F. Zhu*. Molecular
dynamics study and comparison on the binding modes of SSRIs,
sNRIs and SNRIs antidepressants. Invited speaker of
international conference for
BIT’s 6th
Annual International Congress of Medichem-2016
(ICM-2016). China Pharmaceutical University, Nanjing, P. R. China
(2016).
-
G. X.
Zheng, W. W. Xue, F. Zhu*. Exploring the
inhibitory mechanism of approved selective norepinephrine
reuptake inhibitors from molecular dynamics study. Invited
speaker of international conference for
The 4th
International Conference on Molecular Simulation (ICMS
2016). Shanghai Jiao Tong University, Shanghai, P. R. China
(2016).
-
F.
Zhu*. Normalization
and meta-analysis of metabolomics data. Invited speaker of
domestic conference for
The 7th
National Conference on Bioinformatics & System Biology. University of Electronic Science and Technology of China,
Chengdu, P. R. China (2016).
-
F.
Zhu*. Insight into
the pathogenesis of pituitary adenomas by meta-analysis of
transcriptomic and metabolomic Data. Invited speaker of
domestic conference for
The 2016
Conference on Precision Medicine. Xian Jiaotong University, Xian, P. R. China (2016).
-
F.
Zhu*. Identification
of the inhibitory mechanism of FDA approved selective serotonin
reuptake inhibitors: an insight from molecular dynamics
simulation study. Invited speaker of international
conference for
The 12th
Sino-US Chemistry Professors Conference. Sun Yat-sen University, Guangzhou, P. R. China (2016).
-
F.
Zhu*. Discovering
the stable marker identification methods for metabonomics study.
Invited speaker of international conference for
The 2016
Symposium of International Young Distinguished Scholars. Tongji University, Shanghai, P. R. China (2016).
-
F.
Zhu*. Design of
multi-target anticancer drugs by analyzing the protein-protein
interaction network of cancer. Invited speaker of domestic
conference for
The 2nd
Symposium on Bioinformatics and Drug Design. Chongqing University, Chongqing, P. R. China (2016).
-
F.
Zhu*. Meta-analysis
of metabolomic data. Invited speaker of domestic
conference for
The 2016
Conference on Bioinformatics and Intelligent Information
Processing (BIIP2016). Jilin University, Jilin, P. R. China (2016).
-
F.
Zhu*. MMEASE: a
web-server for meta-analysis of metabolomic data by enhanced
metabolite annotation, marker selection and enrichment analysis.
Invited speaker of domestic conference for
The 30th
Academic Annual Conference of the Chinese Chemical
Society. Dalian University of Technology, Dalian, P. R. China
(2016).
-
F.
Zhu*. Identifying
the metabonomics biomarkers. Invited speaker of domestic
conference for
The 2016
Academic Salon of Shanghai Society for Bioinformatics. Fudan University, Shanghai, P. R. China (2016).
-
F.
Zhu*. Insight into
the pathogenesis of pituitary adenomas by meta-analysis of
transcriptomic data. Invited speaker of domestic
conference for
The 2016
Symposium of Big Data and Precision Biomedical
Informatics. Shanghai Jiao Tong University, Shanghai, P. R. China
(2016).
-
W. W.
Xue and F. Zhu*. Identification
of multi-target drug against remote target pair using
combinatorial support vector mechine method. Invited speaker
of domestic conference for
The 13th
National Symposium of Computer & Computational Chemistry. Sun Yat-sen University, Guangzhou, P. R. China (2015).
-
F.
Zhu*. Future
bioprospecting: from the clustered patterns of species origins
of nature-derived drugs. Invited speaker of international
conference for
The 6th
International Conference of Molecular Simulation and
Applied Information Technologies (6th-ICMS&I). China Pharmaceutical University, Nanjing, P. R. China
(2012).
-
F.
Zhu*. Drug discovery
prospect from untapped species: indications from approved
natural product drugs. Invited speaker of international
conference for
International
Symposium on Natural Product Synthesis and Innovative
Process Methods for Drug Manufacture. Chongqing University, Chongqing, P. R. China (2012).
-
F.
Zhu*. Identification
of next generation innovative therapeutic targets: clues from
genetic, structural, physicochemical and system profile of
successful ones. Invited speaker of international
conference for
Singapore
Symposium on Computational Biology 2009 (SYMBIO2009). National University of Singapore, Singapore, Singapore
(2009).
Invited Academic Visit and Presentation (click to show or hide the details)
-
F.
Zhu*. Bioinformatics
tools applied to the research field of brain science. Invited
academic visit by Prof. Bo-Chu Wang to
Bioengineering College, Chongqing University, Chongqing, P. R. China
(2016).
-
F.
Zhu*. Comprehensive
assessment of the popular normalization methods used in
metabonomics study. Invited academic visit by Prof. Yu-Yang
Jiang to
Graduate School at Shenzhen, Tsinghua University, Shenzhen, P. R. China (2016).
-
W. W.
Xue and F. Zhu*. Extension of
bioinformatics to the fields of brain sciences: metabonomics
study of pituitary adenomas and design of multi-target
antidepressants. Invited academic visit by Prof. Han-Bing
Rao to
Faculty of Science, Sichuan Agricultural University, Yaan, P. R. China
(2016).
-
W. W.
Xue and F. Zhu*. Design of
multi-target anticancer drugs by analyzing the protein-protein
interaction network of cancer. Invited academic visit by
Prof. Xiao-Jun Yao to
School of Pharmacy, Lanzhou University, Lanzhou, P. R. China (2014).
-
F.
Zhu*. Computer-aided
drug design based on the complex biological network of cancer.
Invited academic visit by Prof. Cheng-Zhi Huang to
College of Pharmaceutical Sciences and
Chinese Medicine, Southwest University, Chongqing, P. R. China
(2014).
-
F.
Zhu*. Identification
of multi-target anticancer leads using combinatorial machine
learning methods. Invited academic visit by Prof. Wei
Wang to
State Key Laboratory of Applied
Organic Chemistry, Lanzhou University, Lanzhou, P. R. China (2013).
-
F.
Zhu*. Design of
anticancer leads and testing of their bioactivities. Invited
academic visit by Prof. Da-He Liu to
Department of Physics, Beijing Normal University, Beijing, P. R. China
(2013).
-
F.
Zhu*. Find target
and design bullet for the complex network disease - cancer.
Invited academic visit by Prof. Ying Xue to
College of Chemistry, Sichuan University, Chengdu, P. R. China (2013).
-
F.
Zhu*. Targets!
Bullets! Computer-aided drug design from the network medicine
perspective. Invited academic visit by Prof. Han-Bing Rao
to
Faculty of Science, Sichuan Agricultural University, Yaan, P. R. China
(2013).
-
F.
Zhu*. Bioinformatics
identification of anticancer drug targets. Invited academic
visit by Prof. Kun-Xian Shu to
School of Bioinformatics, Chongqing University of Posts and
Telecommunications, Chongqing, P. R. China (2013).
-
F.
Zhu*. Clustered
patterns of species origins of active ingredients in the
traditional chinese medicine. Invited academic visit by Prof.
Qi-Ni Qian to
Chongqing Institute of Medicinal Plant
Cultivation, Chongqing Institute of Medicinal Plant Cultivation,
Chongqing, P. R. China (2013).
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