IDRB: Peoples

ABOUT THE PRINCIPAL INVESTIGATOR

Dr. Feng ZHU

Professor, Zhejiang University (47th in QS World University Rankings ), China

zhufeng(at)zju.edu.cn (primary), prof.zhufeng(at)gmail.com ; +86-571-88208444

PERSONAL DETAILS

Research Interests: Medicinal Chemistry, Drug Design, Target Discovery, Bioinformatics and System Biology

Based on the artificial intelligence and OMIC (proteomics and metabolomics) technologies, we conduct systematical exploration on the druggability and system profile of therapeutic drug targets, develop novel methods and online tools for target discovery, and further study the mechanism underlying the interaction between drugs and their corresponding targets.

Educational Reform Projects (PI: Principal Investigator; PP: Project Participant)

2022.10 - (PI, 省部级): IECC Foundation of the Ministry of Education of China (2022-AliC-4-32)

2024.12 - (PI, 省部级): Teaching Reform Projects in 14th Five-Year Plan of Zhejiang Province (JGCG2024035)

2021.12 - (PI, 省部级): Textbook Construction in 13th Five-Year Plan of Zhejiang Province (2021-135-33)

2025.01 - (PI, 学校级): AI Empowerment Foundation of Zhejiang University (PHAR3513M)

2025.01 - (PI, 学校级): AI Cross-disciplinary Foundation of Zhejiang University (PHAR3513M)

2024.01 - (PI, 学校级): AI4Education Foundation of Zhejiang University (AI4Edu-2024-03)

2024.11 - (PI, 学校级): Excellent Graduate Program (AI Series) of Zhejiang University (ZJUGEExcel-18)

2021.01 - (PI, 学校级): Postgraduate Education Reform Foundation of China (zyjyjx-grazju-49)

2020.06 - (PI, 学校级): Undergraduate Education Reform Foundation of China (068-484607)

2020.09 - (PI, 学校级): Postgraduate Education Reform Foundation of Zhejiang University (1913039)

Published Key Textbooks ( front cover of the book)

2023.01 (Undergraduate Textbook) : "AI in Medicine" ISBN 978-7-308-23491-7, Zhejiang University Press

The Unique Feature of This Book:

Key Textbook for the Universities of Zhejiang Province in the 14th Five-Year Plan

2023.06 (Drug Discovery Book) : "Artificial Intelligence and Drug Design" ISBN 978-7-122-42928-5, Chemical Industry Press

The Unique Feature of This Book:

Key Project Supported by Chinese National Publication Foundation (2023)

2023.03 (Undergraduate Textbook) : "Drug Design" ISBN 978-7-04-059211-5, Higher Education Press

The Unique Feature of This Book:

Key Textbook for the Ministry of Industry and Information Technology of China

Key Textbook for the Medical Education of China in the 14th Five-Year Plan

Key Textbook for the National Education of China in the 11th Five-Year Plan

Licensed Patents and Copyrights

Licensed Invention Patents

Y. Zhang, X. D. Li, Q. Z. Jia, G. X. Liu, D. He, F. Zhu. Invention Patent 2024010500126270 approved by the CNIPA.
Quinazoline-4-amine Derivatives with HDAC Inhibitory Activity, and Their Preparation Methods and Applications (2024)

Licensed Software Copyrights

F. Zhu, M. J. Mou, Z. Q. Pan, Z. M. Zhou. Software Copyright 2024SR1495360 approved by the National NCAC of China.
A Software Tool for Protein-protein Interaction Site Identification (2024)

F. Zhu, H. C. Sun, X. C. Lian, Y. Zhou, et al. Software Copyright 2024SR1495302 approved by the National NCAC of China.
A Software Tool for Quantitative Single-cell Proteomics (2024)

F. Zhu, H. Y. Zhang, Z. C. Zhang, Y. Zhou. Software Copyright 2024SR1495343 approved by the National NCAC of China.
A Software Tool for Drug-drug Interaction and Adverse Drug Reaction Associations (2024)

F. Zhu, H. Y. Zhang, Z. Q. Pan, Y. X. Wang. Software Copyright 2024SR1495370 approved by the National NCAC of China.
A Software Tool for Prediction Interaction Between miRNAs and lncRNAs (2024)

F. Zhu, X. N. Sun, S. Zhang, M. J. Mou, et al. Software Copyright 2023SR0736962 approved by the National NCAC of China.
A Software Tool for Metabolite and Protein Regulatory Network Analysis (2023)

F. Zhu, M. J. Mou, X. N. Sun, C. Y. Zhang. Software Copyright 2023SR0682069 approved by the National NCAC of China.
A Software Tool for Analyzing Biological Activities of Drug Inactive Ingredients (2023)

F. Zhu, X. N. Sun, Y. T. Zhang, H. Y. Li, Y. Zhou. Software Copyright 2023SR0682068 approved by the National NCAC of China.
A Software Tool for Comprehensive Drug Resistance Analysis (2023)

F. Zhu, F. C. Li, H. C. Sun, J. Y. Yin. Software Copyright 2022SR1374536 approved by the National NCAC of China.
A Software Tool for Metabolomics-based Quantitative Analysis of Large-scale and Long-term Microbiota Study (2022)

F. Zhu, J. Y. Yin, F. C. Li, Y. Zhou, M. J. Mou. Software Copyright 2022SR1374538 approved by the National NCAC of China.
A Software Tool for Interaction Analysis of Drug-metabolizing Enzyme Intergroup (2022)

F. Zhu, F. C. Li, J. Y. Yin, M. K. Lu, M. J. Mou. Software Copyright 2022SR1374548 approved by the National NCAC of China.
A Software Tool for Molecular Profiling of Drug Interactions (2022)

F. Zhu, F. C. Li, J. Y. Yin, M. K. Lu, Q. X. Yang. Software Copyright 2022SR1374537 approved by the National NCAC of China.
A Software Tool for Stable Identification of Molecular Features based on OMICS Data (2022)

F. Zhu, F. C. Li, J. Y. Yin, Y. Zhou, Y. Zhang. Software Copyright 2022SR1374547 approved by the National NCAC of China.
A Software Tool for High Precision Identification of Biomarkers Based on Proteomics Technology (2022)

F. Zhu, M. J. Mou, J. Tang, X. N. Sun. Software Copyright 2022SR1096571 approved by the National NCAC of China.
A Software Tool for Analyzing Host Regulatory Factors of Human Microbiota (2022)

F. Zhu, M. J. Mou, J. Tang, Y. X. Wang, et al. Software Copyright 2021SR0027303 approved by the National NCAC of China.
A Software Tool for Selecting Metaproteomic Features Based on Performance Assessment (2021)

F. Zhu, J. Y. Yin, F. C. Li, X. X. Li, et al. Software Copyright 2021SR0822567 approved by the National NCAC of China.
A Software Tool for Constructing Phylogenetic Tree Describing the Homology among Drug Transporters (2021)

F. Zhu, F. C. Li, Y. Zhou, X. Y. Zhang. Software Copyright 2021SR0826823 approved by the National NCAC of China.
A Software Tool for Determining Sample Sufficiency for Comparative Biological Study (2021)

F. Zhu, S. Zeng, J. Y. Yin, F. C. Li. Software Copyright 2020SR0275172 approved by the National NCAC of China.
A Software Tool for Analyzing the Interplay among the Variabilities of Drug Transporters (2020)

F. Zhu, Y. X. Wang, Y. Z. Chen, S. Zhang, et al. Software Copyright 2020SR0526446 approved by the National NCAC of China.
A Software Tool for Integrating the Epigenetics with the Protein-Protein Interactions of Drug Target (2020)

F. Zhu, Y. X. Wang, S. Zhang, F. C. Li, et al. Software Copyright 2020SR0527384 approved by the National NCAC of China.
A Software Tool for Strictly Validating the Primary Drug Target and Conducting Network Analysis (2020)

F. Zhu, Y. X. Wang, S. Zhang, F. C. Li, et al. Software Copyright 2020SR0528155 approved by the National NCAC of China.
A Software Tool for Strictly Identifying the Primary Therapeutic Target of the Drugs in Clinical Trial (2020)

F. Zhu, J. J. Hong, J. Hu, L. Tao. Software Copyright 2020SR0274064 approved by the National NCAC of China.
A Software Tool for Discovering the Bacterial Type-IV Secreting System Effector Protein (2019)

F. Zhu, J. Tang, J. B. Fu, Y. X. Wang. Software Copyright 2020SR0274135 approved by the National NCAC of China.
A Software Tool for Assessing Label-free Proteome Quantification from Multiple Perspectives (2019)

F. Zhu, F. C. Li, S. Zhang, Y. X. Wang, et al. Software Copyright 2020SR0525443 approved by the National NCAC of China.
A Software Tool for Discovering the Novel Drug Scaffold Based on Biomarker Identification (2019)

F. Zhu, F. C. Li, S. Zhang, Y. X. Wang, et al. Software Copyright 2020SR0528147 approved by the National NCAC of China.
A Software Tool for Identifying the Tissue-Specific Distribution Pattern of Therapeutic Target (2018)

F. Zhu, Q. X. Yang, B. Li, Y. X. Wang. Software Copyright 2020SR0275177 approved by the National NCAC of China.
A Software Tool for Evaluating Mass-spectrometry-based Metabolomic Data from Multiple Perspectives (2017)

F. Zhu, S. Zhang, F. C. Li, Y. X. Wang, et al. Software Copyright 2020SR0528618 approved by the National NCAC of China.
A Software Tool for Associating the Disease-Relevant Signaling Pathway with Therapeutic Target (2016)

Hosted Conference and Symposium

President of the Organizing Committee

F. Zhu is the Chair of the Organizing Committee for the 4th Worldwide Chinese Computational Biology Conference. Zhejiang University, Hangzhou, P. R. China (2022).

F. Zhu is the Chair of the Organizing Committee for the 11st Asia Hub for e-Drug Discovery. Zhejiang University, Hangzhou, P. R. China (2021).

F. Zhu is the Chair of the Organizing Committee for the 2nd Symposium on Bioinformatics and Drug Design. Chongqing University, Chongqing, P. R. China (2019).

Member of the Academic Committee

F. Zhu is the Member of the Academic Committee for the 4th Worldwide Chinese Computational Biology Conference. Zhejiang University, Hangzhou, P. R. China (2022).

F. Zhu is the Member of the Academic Committee for the 11st Asia Hub for e-Drug Discovery. Zhejiang University, Hangzhou, P. R. China (2021).

F. Zhu is the Member of the Academic Committee for the 16th National Symposium of Computer & Computational Chemistry. Jilin University, Changchun, P. R. China (2021).

F. Zhu is the Member of the Academic Committee for the 15th National Symposium of Computer & Computational Chemistry. Fudan University, Shanghai, P. R. China (2019).

F. Zhu is the Member of the Academic Committee for the 14th National Symposium of Computer & Computational Chemistry. Nanjing University, Nanjing, P. R. China (2017).

F. Zhu is the Member of the Academic Committee for The Second CCF Bioinformatics Conference (CBC-2017). Central South University, Changsha, P. R. China (2017).

F. Zhu is the Member of the Academic Committee for the 2nd Symposium on Bioinformatics and Drug Design. Chongqing University, Chongqing, P. R. China (2019).

F. Zhu is the Member of the Academic Committee for the 13th National Symposium of Computer & Computational Chemistry. Sun Yat-sen University, Guangzhou, P. R. China (2015).

Symposium Chairman or Organizing Committee Member

F. Zhu is the Chairman of the Symposium II (chemometrics and life science) for the 16th National Symposium of Computer & Computational Chemistry. Jilin University, Changchun, P. R. China (2021).

F. Zhu is the Chairman of the Symposium IV (precision drug design and precision medicine) for the 15th National Symposium of Computer & Computational Chemistry. Fudan University, Shanghai, P. R. China (2019).

F. Zhu is the Chairman of the Symposium II (OMIC big data and medical application) for the Fourth CCF Bioinformatics Conference. South China University of Technology, Guangzhou, P. R. China (2019).

F. Zhu is the Member of the Academic Committee for the Fourth CCF Bioinformatics Conference. South China University of Technology, Guangzhou, P. R. China (2019).

F. Zhu is the Vice-chairman of the Symposium 24 Session-4 for the 31st Academic Annual Conference of the Chinese Chemical Society. Zhejiang University, Hangzhou, P. R. China (2018).

F. Zhu is the Chairman of the Symposium IV Session -7 for Asian Federation for Pharmaceutical Sciences Conference 2017. Xiamen University, Xiamen, P. R. China (2017).

F. Zhu is the Chairman of the sub-conference 103 (multi-target and protein-protein interaction) for BIT’s 6th Annual International Congress of Medichem-2016 (ICM-2016). China Pharmaceutical University, Nanjing, P. R. China (2016).

F. Zhu is the Vice-chairman of the 6th theme (study on drug transporter and PK/PD) for BIT’s 6th Annual International Congress of Medichem-2016 (ICM-2016). China Pharmaceutical University, Nanjing, P. R. China (2016).

F. Zhu is the Member of the Organizing Committee for International Symposium on Natural Product Synthesis and Innovative Process Methods for Drug Manufacture. Chongqing University, Chongqing, P. R. China (2012).

Invited Speaker of International/Domestic Conference

Keynote Speaker

Strategy Seminar on Chemistry Division of the National Natural Science Foundation of China & 2021 Annual National Computational Toxicology Conference of China. Yan'an University, Yanan, China (2021)

2020 Annual Conference of Digitization in Medical Administration and Artificial Intelligence in Drug Discovery. Zhejiang Medical Association, Hangzhou, China (2021)

2020 Annal Symposium on Translational Medicine, Bioinformatics and Genomics/Proteomics/Metabolomics-based Technology. Chongqing Medical University, Chongqing, China (2020)

2019 Forum of Intelligent Development of Traditional Chinese Medicine. China Information Association of Traditional Chinese Medicine, Shanghai, China (2019)

1st West Lake Clinical Research and Evaluation Conference and Annual Conference of the Clinical Trial Committee of Zhejiang Pharmaceutical Association. The First Affiliated Hospital, Zhejiang University, Hangzhou, China (2018)

11th China-Japan Symposium on Molecular Drug Design and Development. Zhejiang University and Peking Union Medical College, Chinese Academy of Medical Sciences, Shaoxing, China (2018)

2017 Symposium on Pharmaceutical Chemistry of the Yangtze River Delta Metropolitan Region. Hefei Institute of Physical Science, Chinese Academy of Sciences, Hefei, China (2017)

Invited Speaker

The PacifiChem 2021 Symposium. International Chemical Congress of Pacific Basin Societies, Hawaii, USA (2021)

The AHeDD2019/IPAB2019 Joint Symposium. Tokyo Institute of Technology, Kawasaki, Japan (2019)

15th National Symposium of Computer & Computational Chemistry. Fudan University, Shanghai, China (2019)

4th China Analytical Pharmacology Conference. Shenyang Pharmaceutical University, Shenyang, China (2019)

Computational Drug Discovery and ACM Chinese Council. Central South University, Changsha, China (2019)

CPA-EFMC International Symposium on Medicinal Chemistry. Sichuan University, Chengdu, China (2019)

Jiangsu-Zhejiang International Symposium of Bioinformatics. Jiangnan University, Wuxi, China (2019)

3rd Conference for Analytical Pharmacology of CNPHARS. Zunyi Medical University, Zuiyi, China (2018)

10th National Symposium of Genetics Society of China. Nanjing Agricultural University, Nanjing, China (2018)

14th Symposium of the CPA Youth Pharmacologist. Chinese Pharmaceutical Association, Hangzhou, China (2018)

2nd Worldwide Computational Biology and Molecular Simulation Conference. Sun Yat-sen University, Guangzhou, China (2018)

31st Academic Annual Conference of the Chinese Chemical Society. Zhejiang University, Hangzhou, China (2018)

Asian Federation for Pharmaceutical Sciences Conference 2017. Xiamen University, Xiamen, China (2017)

14th National Symposium of Computer & Computational Chemistry. Nanjing University, Nanjing, China (2017)

5th Academic Forum for Postgraduates. Sichuan University, Chengdu, China (2017)

2nd Conference on Innovative Drug Research and Application. Nanjing Biotech and Pharmaceutical Valley, Nanjing, China (2017)

Bioinformatics and Intelligent Information Processing Conference. Shanghai Jiao Tong University, Shanghai, China (2017)

Fifth Young Scholars Forum for Interdisciplinary Researches. Chinese Academy of Sciences, Beijing, China (2017)

2017 (the second) Conference on Precision and Future Medicine. Zhejiang University, Hangzhou, China (2017)

China Society of Biotechnology Young Scientists Forum II. South China University of Technology, Guangzhou, China (2017)

2016 Symposium of Guanghua Young Distinguished Scholars. Fudan University, Shanghai, China (2016)

BIT’s 6th Annual International Congress of Medichem-2016. China Pharmaceutical University, Nanjing, China (2016)

1st International Symposium on Targeted Therapeutics. Chongqing University of Arts and Sciences, Chongqing, China (2016)

4th International Conference on Molecular Simulation. Shanghai Jiao Tong University, Shanghai, China (2016)

7th National Conference on Bioinformatics. University of Electronic Science and Technology of China, Chengdu, China (2016)

2016 Conference on Precision Medicine. Xian Jiaotong University, Xian, China (2016)

12th Sino-US Chemistry Professors Conference. Sun Yat-sen University, Guangzhou, China (2016)

2016 Symposium of International Young Distinguished Scholars. Tongji University, Shanghai, China (2016)

2nd Symposium on Bioinformatics and Drug Design. Chongqing University, Chongqing, China (2016)

2016 Conference on Bioinformatics and Intelligent Information Processing. Jilin University, Jilin, China (2016)

30th Academic Annual Conference of the Chinese Chemical Society. Dalian University of Technology, Dalian, China (2016)

2016 Academic Salon of Shanghai Society for Bioinformatics. Fudan University, Shanghai, China (2016)

2016 Symposium of Big Data and Precision Biomedical Informatics. Shanghai Jiao Tong University, Shanghai, China (2016)

13th National Symposium of Computer & Computational Chemistry. Sun Yat-sen University, Guangzhou, China (2015)

6th International Conference of Molecular Simulation. China Pharmaceutical University, Nanjing, China (2012)

CURRENT GROUP MEMBERS

PROFESSOR AND LECTURER

Wei-Wei XUE
Cheminformatics

2014.06-now

2016.09-Now: Assoc. Professor in School of Pharmaceutical Sciences, CQU
2014.06-2016.09: Lecturer in Innovative Drug Research Centre, CQU
2009.09-2014.06: Master, Doctor in Department of Chemistry, LZU
2005.09-2009.06: Bachelor in Department of Chemistry, LZU

POSTDOCTORAL FELLOW

Yi-chao GE
Marine Science and Engineering

2023.07-now

2023.07-Now: Postdoctoral Fellow in College of Pharmaceutical Science, ZJU
2018.09-2023.03: Doctor in Ocean College, ZJU
2015.09-2018.03: Master, Doctor in School of Food Science and Biotechnology, ZJGSU
2011.09-2015.06: Bachelor in College of Biological & Environmental Sciences, ZJWU

Ting-Ting FU
Medicinal Chemistry

2023.09-now

2023.09-Now: Postdoctoral Fellow in College of Pharmaceutical Science, ZJU
2019.09-2023.09: Doctor in Institute of Theoretical Chemistry, JLU
2016.09-2019.06: Master, Doctor in School of Pharmaceutical Science, CQU
2012.09-2016.06: Bachelor in College of Veterinary Medicine, SAU

DOCTORAL CANDIDATE

Yong-Chao Luo
Pharmacy

2018.07-now

Ting-Ting Fu
Medicinal Chemistry

2019.09-now

Ying Zhou
Pharmacy

2019.01-now

Ying Zhang
Pharmacy

2019.01-now

Min-Jie Mou
Pharmacy

2019.05-now

Yin-Tao Zhang
Pharmacy

2019.09-now

GRADUATE STUDENT

Jing-Yi Yang Medicinal Chemistry 2018.09-now	Zhao Zhang Medicinal Chemistry 2019.09-now	Xiu-Na Sun Pharmacy 2020.09-now
Xi-Chen Lian Pharmacy 2020.09-now	Kuerbannisha Amahong Pharmacy 2020.09-now	Han-Yu Zhang Pharmacy 2020.09-now
Xiao-Na Wang Pharmacy 2020.09-now	Bin-Bin Xu Pharmacy 2020.09-now	Ling-Yan Zheng Pharmacy 2020.09-now
Huai-Cheng Sun Pharmacy 2021.03-now	Ming-Kun Lu Pharmacy 2021.03-now	Shui-Yang Shi Pharmacy 2021.03-now
Wei Zhang Pharmacy 2021.03-now	Han-Yang Li Pharmacy 2021.03-now	Zi-Qi Pan Pharmacy 2022.09-now
Zhen Chen Pharmacy 2022.09-now	Teng Li Pharmacy 2022.09-now	Nan-Xin You Pharmacy 2022.09-now
Shi-Jie Huang Pharmacy 2022.09-now	Zhi-Meng Zhou Pharmacy 2023.09-now	Xin-Yuan Yu Pharmacy 2023.09-now
Yuan Zhou Pharmacy 2023.09-now	Zhi-Chao Zhang Pharmacy 2023.09-now	Yang Liao Pharmacy 2023.09-now

CHINESE NATIONAL UNDERGRADUATE INNOVATIVE TEST PROGRAM AND STUDENT RESEARCH TRAINING PROGRAM

Kang-Li Chen
Pharmacy

2020.03-now

Han-Xiang Xu
Pharmacy

2020.03-now

Han-Qi Zheng
Pharmacy

2020.03-now

IDRB: Innovative Drug Research and Bioinformatics Group

All rights are reserved by: Innovative Drug Research and Bioinformatics Group (IDRB)
College of Pharmaceutical Sciences, Zhejiang University
Hangzhou, P.R. China, 310058.
Contact number: (86 - 571)88208444
ICP ID: 浙ICP备18036997号-1

Last Update: