Zhejiang U | College of Pharmaceutical Sciences | 中文版
     
     
Feng ZHU - IDRC - Chongqing University
ABOUT THE PRINCIPAL INVESTIGATOR

Dr. Feng ZHU

Professor, Doctoral advisor, H-index & My Citations (Google Scholar)

Member of Computational Chemistry Professional Committee of CCS and Task Force on Bioinformatics Professional Committee of CCF; Vice President of Chongqing Bioinformatics Society

zhufeng@zju.edu.cn (primary), prof.zhufeng@gmail.com; +86-571-88208444
RESEARCH INTERESTS
Medicinal Chemistry, Drug Design, Target Discovery, Bioinformatics and System Biology

Based on the artificial intelligence and OMIC (proteomics and metabolomics) technologies, we conduct systematical exploration on the druggability and system profile of therapeutic drug targets, develop novel methods and online tools for target discovery, and further study the mechanism underlying the interaction between drugs and their corresponding targets.

ACADEMIC APPOINTMENTS
2017.07 - Now: Professor & Doctoral Advisor in College of Pharmaceutical Sciences, Zhejiang University

2016.10 - Now: Vice President of the Chongqing Bioinformatics Society

2016.06 - Now: Committee Member of the CCF Task Force on Bioinformatics

2016.02 - Now: Committee Member of the CNPHARS Precision Pharmacology

2014.09 - Now: Committee Member in CCS Computational Chemistry

2014.02 - 2017.06: Professor & Doctoral Advisor in School of Pharmaceutical Sciences, Chongqing University

2012.07 - 2014.02: PI & Doctoral Advisor in Innovative Drug Research Centre, Chongqing University

2012.01 - 2012.07: Research Fellow in Department of Pharmacy, National University of Singapore

2011.01 - 2011.12: Research Associate in Department of Pharmacy, National University of Singapore

2010.07 - 2011.01: Research Assistant in Department of Pharmacy, National University of Singapore

EDUCATIONAL QUALIFICATIONS
2006.08 - 2011.05: Doctor of Philosophy in Department of Pharmacy, National University of Singapore, Singapore

2003.08 - 2006.07: Master of Science in Key Laboratory of Applied Optics, Beijing Normal University, Beijing, P. R. China

1999.08 - 2003.07: Bachelor of Science in Department of Physics, Beijing Normal University, Beijing, P. R. China

RESEARCH GRANTS
Project on going

2019.01 - (PI): National Natural Science Foundation of China - The General Program (81872798)

2018.09 - (PP): National Key Research and Development Program of China (SQ2018YFC090124)

2018.01 - (PI): Zhejiang University Youth Research Innovation Grant (ZJU2018PHA06)

2017.07 - (PI): Zhejiang University "100-Plan Professor" Grant (ZJU2017070)

2016.08 - (PI): National Key Research and Development Program of China (2016YFC0902200)

2015.12 - (PI): Chongqing Special Funds for (Chemical) Drug Discovery (cstc2015zdcy-ztzx120003)


Project finished

2014.06 - (PI): Fundamental Research Funds for the Central Universities (CDJZR14 46 88 01, evaluated as "Excellent")

2013.01 - (PI): Fundamental Research Funds for the Central Universities (CQDXWL-2012-Z003, evaluated as "Excellent")

2013.01 - (PI): National Natural Science Foundation of China - The Youth Program (81202459)

2012.09 - (PI): Chongqing Natural Science Foundation (cstc2012jjA10116)

2012.08 - (PP): Tianjin Key Technology Support Program (tjkjzc2013zd01)

2012.07 - (PI): Youth 100 Talents Program of Chongqing University (0903005203176, evaluated as "Excellent")

PI: Principal Investigator; PP: Project Participant.
SELECTED PUBLICATIONS

  1. Y. H. Li, C. Y. Yu, X. X. Li, P. Zhang, J. Tang, Q. X. Yang, T. T. Fu, X. Y. Zhang, X. J. Cui, G. Tu, Y. Zhang, S. Li, F. Y. Yang, Q. Sun, C. Qin, X. Zeng, Z. Chen, Y. Z. Chen*, F. Zhu*. Therapeutic target database update 2018: enriched resource for facilitating bench-to-clinic research of targeted therapeutics. Nucleic Acids Res (impact factor of the publication year: 11.561, 生物一区 TOP 期刊). 46(D1): 1121-1127 (2018).
  2. ESI Highly Cited Paper:
    • The Percentile in Subject Area shown in InCites™ was 0.36% in 2018.
    Highlights by Experts in Subject Area:
    • Introduced by OMICTOOLS as "useful for facilitating patient focused research, discovery and clinical investigations of the targeted therapeutics".

  3. F. Zhu*, X. X. Li, S. Y. Yang, Y. Z. Chen*. The clinical success of drug targets prospectively predicted by the in-silico study. Trends Pharmacol Sci (impact factor of the publication year: 12.797, 医学一区 TOP 期刊). 39(3): 229-231 (2018).
  4. ESI Highly Cited Paper:
    • The Percentile in Subject Area shown in InCites™ was 0.21% in 2018.

  5. B. Li, J. Tang, Q. X. Yang, S. Li, X. J. Cui, Y. H. Li, Y. Z. Chen, W. W. Xue, X. F. Li, F. Zhu*. NOREVA: normalization and evaluation of MS-based metabolomics data. Nucleic Acids Res (impact factor of the publication year: 10.162, 生物一区 TOP 期刊). 45(W1): 162-170 (2017).
  6. ESI Highly Cited Paper:
    • The Percentile in Subject Area shown in InCites™ was 2.98% in 2018.
    Highlights by Experts in Subject Area:
    • Introduced by OMICTOOLS as "provided valuable guidance to the selection of suitable algorithm in metabolomics".
    • Discussed in StackExchange as "works fine" and "corrections for batches without QC options".

  7. H. Yang, C. Qin, Y. H. Li, L. Tao, J. Zhou, C. Y. Yu, F. Xu, Z. Chen, F. Zhu*, Y. Z. Chen*. Therapeutic target database update 2016: enriched resource for bench to clinical drug target and targeted pathway information. Nucleic Acids Res (impact factor of the publication year: 9.202, 生物一区 TOP 期刊). 44(D1): 1069-1074 (2016).
  8. ESI Highly Cited Paper:
    • The Percentile in Subject Area shown in InCites™ was 0.71% in 2018.
    • The Percentile in Subject Area shown in InCites™ was 0.87% in 2017.

  9. L. Tao, F. Zhu, C. Qin, C. Zhang, F. Xu, C. Y. Tan, Y. Y. Jiang*, Y. Z. Chen*. The nature's contribution to today's pharmacopeia. Nat Biotechnol (impact factor of the publication year: 32.438, 工程一区 TOP 期刊). 32(10): 979-980 (2014).
  10. F. Zhu, Z. Shi, C. Qin, L. Tao, X. Liu, F. Xu, L. Zhang, Y. Song, X. H. Liu, J. X. Zhang, B. C. Han, P. Zhang, Y. Z. Chen*. Therapeutic target database update 2012: a resource for facilitating target-oriented drug discovery. Nucleic Acids Res (impact factor of the publication year: 8.026, 生物一区 TOP 期刊). 40(D1): 1128-1136 (2012).
  11. ESI Highly Cited Paper:
    • The Percentile in Subject Area shown in InCites™ was 0.62% in 2018.
    • The Percentile in Subject Area shown in InCites™ was 0.31% in 2017.
    Highlights by Experts in Subject Area:
    • "FACULTYof1000" as "the top 2% of published articles in biology and medicine" and "a most useful resource for scientists and companies working on drug discovery and validation, drug lead discovery and optimization, and the development of multi-target drugs and drug combinations".
    • Prof. Chris Southan in his blog as "Therapeutic Target Database in PubChem".

  12. F. Zhu, C. Qin, L. Tao, X. Liu, Z. Shi, X. H. Ma, J. Jia, Y. Tan, C. Cui, J. S. Lin, C. Y. Tan, Y. Y. Jiang*, Y. Z. Chen*. Clustered patterns of species origins of nature-derived drugs and clues for future bioprospecting. Proc Natl Acad Sci U S A (impact factor of the publication year: 9.432, 综合性一区 TOP 期刊). 108(31): 12943-12948 (2011).
  13. ESI Highly Cited Paper:
    • The Percentile in Subject Area shown in InCites™ was 1.16% in 2018.
    • The Percentile in Subject Area shown in InCites™ was 1.91% in 2017.
    Highlights by Experts in Subject Area: Media Coverage & News Report:

  14. H. B. Rao#, F. Zhu#, G. B. Yang, Z. R. Li*, Y. Z. Chen. Update of PROFEAT: a web server for computing structural and physicochemical features of proteins and peptides from amino acid sequences. Nucleic Acids Res (impact factor of the publication year: 7.836, 生物一区 TOP 期刊). 39(W1): 385-390 (2011).
  15. F. Zhu, B. C. Han, P. Kumar, X. H. Liu, X. H. Ma, X. N. Wei, L. Huang, Y. F. Guo, L. Y. Han, C. J. Zheng, Y. Z. Chen*. Update of TTD: therapeutic target database. Nucleic Acids Res (impact factor of the publication year: 7.479, 生物一区 TOP 期刊). 38(D1): 787-791 (2010).
  16. ESI Highly Cited Paper:
    • The Percentile in Subject Area shown in InCites™ was 2.95% in 2017.

  17. J. Jia, F. Zhu, X. H. Ma, Z. W. Cao, Y. X. Li, Y. Z. Chen*. Mechanisms of drug combinations: interaction and network perspectives. Nat Rev Drug Discov (impact factor of the publication year: 23.308, 医学一区 TOP 期刊). 8(2): 111-128 (2009).
  18. ESI Highly Cited Paper:
    • The Percentile in Subject Area shown in InCites™ was 1.13% in 2018.
    • The Percentile in Subject Area shown in InCites™ was 1.39% in 2017.
HOSTED CONFERENCE AND SYMPOSIUM

    Vice-chairman of the Symposium 24 Session-4 for The 31st Academic Annual Conference of the Chinese Chemical Society. Zhejiang University, Hangzhou, P. R. China (2018)

    Chairman of the Symposium IV Session -7 (metabonomics) for Asian Federation for Pharmaceutical Sciences Conference 2017. Xiamen University, Xiamen, P. R. China (2017)

    Member of the Academic Committee for The 14th National Symposium of Computer & Computational Chemistry. Nanjing University, Nanjing, P. R. China (2017)

    Member of the Academic Committee for The Second CCF Bioinformatics Conference (CBC-2017). Central South University, Changsha, P. R. China (2017)

    Chairman of the sub-conference 103 (multi-target and protein-protein interaction) for BIT’s 6th Annual International Congress of Medichem-2016 (ICM-2016) . China Pharmaceutical University, Nanjing, P. R. China. (2016)

    Vice-chairman of the 6th theme (study on drug transporter and PK/PD) for BIT’s 6th Annual International Congress of Medichem-2016 (ICM-2016) . China Pharmaceutical University, Nanjing, P. R. China. (2016)

    Chair of the Organizing Committee and the Member of the Academic Committee for The 2nd Symposium on Bioinformatics and Drug Design. Chongqing University, Chongqing, P. R. China. (2016)

    Member of the Academic Committee for The 13th National Symposium of Computer & Computational Chemistry. Sun Yat-sen University, Guangzhou, P. R. China. (2015)

    Member of the Organizing Committee for International Symposium on Natural Product Synthesis and Innovative Process Methods for Drug Manufacture. Chongqing University, Chongqing, P. R. China. (2012)

INVITED SPEAKER OF INTERNATIONAL AND DOMESTIC CONFERENCE
REVIEWER OF ESTEEMED JOURNALS (ordered alphabetically)
ACS Chem Neurosci; Aging Dis; Amino Acids; Anal Chem; Artif Cells Nanomed Biotechnol; Bioinformatics; BMC Bioinformatics; Brief Bioinform; CNS Neurosci Ther; Curr Pharm Des; Drug Dev Res; Expert Opin Ther Targets; Front Pharmacol; J Chem Inf Model; J Mol Graph Model; J Pharmacol Exp Ther; Med Res Rev; Microb Pathog; Mol Biosyst; Mol Pharmaceut; Mol Pharmacol; Mol Simul; Pharmacol Res; Phys Chem Chem Phys; Nucleic Acids Res; Sci Rep

CURRENT GROUP MEMBERS
PROFESSOR AND LECTURER
Wei-Wei XUE
Cheminformatics

2014.06-now

Personal Homepage Email

2016.09-Now: Assoc. Professor in School of Pharmaceutical Sciences, CQU

2014.06-2016.09: Lecturer in Innovative Drug Research Centre, CQU

2009.09-2014.06: Master, Doctor in Department of Chemistry, LZU

2005.09-2009.06: Bachelor in Department of Chemistry, LZU

DOCTORAL CANDIDATE

Jing TANG
Medicinal Chemistry

2016.09-now
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Zhi-Jie HAN
Bioinformatics

2016.09-now
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Yang ZHANG
Medicinal Chemistry

2016.09-now
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Feng-Yuan YANG
Bioinformatics

2017.09-now
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Qing-Xia YANG
Bioinformatics

2017.09-now
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Jian-bo FU
Medicinal Chemistry

2017.09-now
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Song ZHANG
Medicinal Chemistry

2018.07-now
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GRADUATE STUDENT

Xiao-Xu LI
Medicinal Chemistry

2016.09-now
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Xue-Jiao CUI
Medicinal Chemistry

2016.09-now
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Xiao-Yu ZHANG
Medicinal Chemistry

2016.09-now
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Ting-Ting FU
Medicinal Chemistry

2016.09-now
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Gao TU
Bioinformatics

2017.09-now
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Jia-Jun HONG
Medicinal Chemistry

2017.09-now
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Yun-xia WANG
Medicinal Chemistry

2018.09-now
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Feng-Cheng LI
Medicinal Chemistry

2018.09-now
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Jia-Yi YIN
Medicinal Chemistry

2018.09-now
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STUDENT RESEARCH PROGRAM (SRP)

Zi-Yu Xiao
Pharmacy

2018.06-now
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Run-Yuan Zhang
Pharmacy

2018.06-now
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Jiang Zhu
Pharmacy

2018.06-now
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RESEARCH INTERSHIP

Yong-Chao Luo
Pharmacy

2018.07-now
Home Email

Former GROUP MEMBERS
DOCTORAL GRADUATES

Xiao-Feng LI
Medicinal Chemistry

Chongqing Normal University P.R. China, Lecturer
2014.09-2018.06
Home Email

Ying-Hong LI
Bioinformatics

(To be available) P.R. China, Research Scientist
2015.09-2018.06
Home Email

Guo-Xun ZHENG
Medicinal Chemistry

(To be available) P.R. China, Research Scientist
2015.09-2018.06
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Bo LI
Cell Biology

Chongqing Normal University P.R. China, Lecturer
2013.09-2017.06
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Pan-Pan WANG
Medicinal Chemistry

Huanghuai University Henan P.R. China, Lecturer
2013.09-2017.06
Home Email

MASTER GRADUATES

Chun-Yan YU
Bioinformatics

Nanjing Gezhi Genomics Technologies Company, Bioinformatics Engineer
2015.09-2018.06
Home Email

Shuang LI
Bioinformatics

Biosan Biochemical Technologies Company, Bioinformatics Engineer
2015.09-2018.06
Home Email

Hong YANG
Bioinformatics

Third Military Medical University P.R. China, Research Assistant
2014.09-2017.06
Home Email

Xiao-Fei XU
Bioinformatics

Third Military Medical University P.R. China, Research Fellow
2014.09-2017.06
Home Email

Jin ZHOU
Biochemistry

Hospital in Guizhou Province of P.R.China, Pharmacist
2013.09-2016.06
Home Email

Yan-Ping JING
Medicinal Chemistry

Hospital in Hunan Province of P.R.China, Pharmacist
2013.09-2016.06
Home Email

CHINESE NATIONAL UNDERGRADUATE INNOVATIVE TEST PROGRAM (NUITP)

Li-Zhi ZHANG
Computer Science

Institute of Computing CAS P.R.China, Ph.D Candidate
2013.02-2014.06
Home Email

Jiang-Tao PENG
Communication Engineering

Shanghai Jiao Tong University P.R.China, Ph.D Candidate
2013.02-2014.06
Home Email

Yan DING
Mechanical Automation

Chongqing University P.R.China, Ph.D Candidate
2013.02-2014.06
Home Email

STUDENT RESEARCH PROGRAM (SRP)

Ao-Xing PI
Computer Science

Chongqing University P.R.China, Master Student
2013.02-2014.06
Home Email

Xiang-Han LIN
Mechanical Engineering

Shanghai Jiao Tong University P.R.China, Ph.D Candidate
2013.02-2014.06
Home Email

Zi-Kun WANG
Elec. and Infor. Engineering

Chongqing University P.R.China, Master Student
2013.02-2014.06
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FINAL YEAR PROJECT AND UNDERGRADUATE STUDENT

Xin-Yue Rao
Pharmacy

Southwest University P.R.China, Master Student
2017.02-2017.06
Home Email

Zhao-Yu Wu
Pharmacy

Chongqing University P.R.China, Master Student
2017.02-2017.06
Home Email

Ying-Long LI
Communication Engineering

Chongqing University P.R.China, Undergraduate Student
2014.02-2015.06
Home Email

Si-Yuan CUI
Communication Engineering

Chongqing University P.R.China, Undergraduate Student
2014.02-2015.06
Home Email

Wen-Chen LI
Communication Engineering

Chongqing University P.R.China, Undergraduate Student
2014.02-2015.06
Home Email

Tian-Chi LI
Communication Engineering

Chongqing University P.R.China, Undergraduate Student
2014.02-2015.06
Home Email

Shi-Qin ZHAO
Pharmacy

China Construction Bank (CCB) P.R.China, Officer
2014.02-2014.06
Home Email

Yu-Zi ZHANG
Pharmacy

Chongqing University P.R.China, Undergraduate Student
2014.02-2014.06
Home Email

Jiang YU
Communication Engineering

Huawei Technologies Co., Ltd. P.R.China, Technological Officer
2013.02-2014.06
Home Email

Rong HUANG
Communication Engineering

University of Electronic Science and Technology of China, Master Student
2013.02-2014.06
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Yong-Zhou LI
Computer Science

Beijing University of Posts and Telecommunications, Master Student
2013.02-2014.06
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RESEARCH INTERSHIP

Min Xi
Bioinformatics

Chongqing University P.R. China, Master Student
2017.04-2017.09
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Juan Zhang
Bioinformatics

Chongqing University P.R. China, Master Student
2017.04-2017.09
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Zhen-Tang Tan
Bioinformatics

Chongqing University P.R.China, Internship Researcher
2017.03-2018.08
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Qiu SUN
Bioinformatics

Chongqing University of Posts and Telecommunications, Master Student
2016.09-2017.06
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Si-Jie CHEN
Computer Science

Tsinghua University P.R.China, Ph.D Candidate
2015.10-2016.02
Home Email

Xiao-Huan LIU
Applied Mathematics

Local Government of Chengdu P.R.China, Officer
2014.09-2015.11
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Na CHEN
Medicinal Chemistry

Chongqing University P.R. China, Master Student
2014.09-2017.06
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IDRB: Innovative Drug Research and Bioinformatics Group

255368   visits since 2012
All rights are reserved by: Innovative Drug Research and Bioinformatics Group (IDRB)
College of Pharmaceutical Sciences, Zhejiang University
Hangzhou, P.R. China, 310058.
Contact number: (86 - 571)88208444

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