Detail Information of Microbiota Influence

General Information of Drug Transporter (DT)
DT ID	DTD0081 Transporter Info
Gene Name	SLC11A2
Transporter Name	Natural resistance-associated macrophage protein 2
Gene ID	4891
UniProt ID	P49281

Microbiota Influence of This DT (MBI)

Bacteria: Actinomycetota
Genus: Corynebacterium
Corynebacterium diphtheriae	Microbe Info	Click to Show/Hide the Full List 2 Microbe Influence Related to This Species
Microbe Influence1	Sequestration of human SLC11A2 substrates/drugs in the health condition		[1], [2], [3], [4]
Regulating Factor	Corynebactin
Detailed Description	The compound Corynebactin Secreted by Corynebacterium diphtheriae C7 (beta) has been reported to sequester the substrate/drug of SLC11A2, which may affects its substrate/drug distribution in the body.
Microbe Influence2	Co-transport of human SLC11A2 substrates/drugs in the health condition		[5], [6], [7], [8]
Regulating Factor	MntABCD , , ,
Detailed Description	The protein MntABCD of Corynebacterium diphtheriae C7 (beta) has been reported to transport similar substrates/drugs of SLC11A2, which affects the distribution of its substrate/drug in vivo.
Genus: Mycobacterium
Mycobacterium avium	Microbe Info	Click to Show/Hide the Full List 2 Microbe Influence Related to This Species
Microbe Influence1	Sequestration of human SLC11A2 substrates/drugs in the health condition		[9], [10], [11], [12]
Regulating Factor	Mycobactin
Studied Tissue	Blood
In Vivo Model	C57BL/6 mice
Detailed Description	The compound mycobactin secreted by Mycobacterium avium 101 has been reported to sequester the substrate/drug of SLC11A2, which may affects its substrate/drug distribution in the body.
Microbe Influence2	Sequestration of human SLC11A2 substrates/drugs in the health condition		[13], [3], [4]
Regulating Factor	Carboxymycobactin
Detailed Description	The compound Carboxymycobactin Secreted by Mycobacterium avium CRl/69 has been reported to sequester the substrate/drug of SLC11A2, which may affects its substrate/drug distribution in the body.
Mycobacterium tuberculosis	Microbe Info	Click to Show/Hide the Full List 11 Microbe Influence Related to This Species
Microbe Influence1	Sequestration of human SLC11A2 substrates/drugs in the health condition		[9], [10], [11], [12]
Regulating Factor	Mycobactin
Studied Tissue	Blood
In Vivo Model	C57BL/6 mice
Detailed Description	The compound Mycobactin Secreted by Mycobacterium tuberculosis H37Rv has been reported to sequester the substrate/drug of SLC11A2, which may affects its substrate/drug distribution in the body.
Microbe Influence2	Sequestration of human SLC11A2 substrates/drugs in the health condition		[3], [4], [9], [14]
Regulating Factor	Desferriexochelin 772MS
Detailed Description	The compound Desferriexochelin 772MS Secreted by Mycobacterium tuberculosis str. Erdman has been reported to sequester the substrate/drug of SLC11A2, which may affects its substrate/drug distribution in the body.
Microbe Influence3	Sequestration of human SLC11A2 substrates/drugs in the health condition		[11], [12], [15], [16]
Regulating Factor	Mycobactin
Detailed Description	The compound mycobactin secreted by Mycobacterium tuberculosis has been reported to sequester the substrate/drug of SLC11A2, which may affects its substrate/drug distribution in the body.
Microbe Influence4	Sequestration of human SLC11A2 substrates/drugs in the health condition		[9], [3], [4]
Regulating Factor	desA1
Detailed Description	The protein desA1 of Mycobacterium tuberculosis H37Ra has been reported to sequester the substrate/drug of SLC11A2, which may affects its substrate/drug distribution in the body.
Microbe Influence5	Sequestration of human SLC11A2 substrates/drugs in the health condition		[9], [3], [4]
Regulating Factor	GAPDH
Detailed Description	The protein GAPDH of Mycobacterium tuberculosis H37Ra has been reported to sequester the substrate/drug of SLC11A2, which may affects its substrate/drug distribution in the body.
Microbe Influence6	Co-transport of human SLC11A2 substrates/drugs in the health condition		[9], [17], [4]
Regulating Factor	IrtAB ,
Detailed Description	The protein IrtAB of Mycobacterium tuberculosis H37Rv has been reported to transport similar substrates/drugs of SLC11A2, which affects the distribution of its substrate/drug in vivo.
Microbe Influence7	Co-transport of human SLC11A2 substrates/drugs in the health condition		[5], [6], [11], [12], [18]
Regulating Factor	mntH
Detailed Description	The protein mntH of Mycobacterium tuberculosis H37Rv has been reported to transport similar substrates/drugs of SLC11A2, which affects the distribution of its substrate/drug in vivo.
Microbe Influence8	Sequestration of human SLC11A2 substrates/drugs in the health condition		[9], [3], [4]
Regulating Factor	Rv0641
Detailed Description	The protein Rv0641 of Mycobacterium tuberculosis H37Ra has been reported to sequester the substrate/drug of SLC11A2, which may affects its substrate/drug distribution in the body.
Microbe Influence9	Sequestration of human SLC11A2 substrates/drugs in the health condition		[9], [3], [4]
Regulating Factor	Rv0704
Detailed Description	The protein Rv0704 of Mycobacterium tuberculosis H37Ra has been reported to sequester the substrate/drug of SLC11A2, which may affects its substrate/drug distribution in the body.
Microbe Influence10	Sequestration of human SLC11A2 substrates/drugs in the health condition		[9], [3], [4]
Regulating Factor	Rv1872c
Detailed Description	The protein Rv1872c of Mycobacterium tuberculosis H37Ra has been reported to sequester the substrate/drug of SLC11A2, which may affects its substrate/drug distribution in the body.
Microbe Influence11	Sequestration of human SLC11A2 substrates/drugs in the health condition		[9], [3], [4]
Regulating Factor	tuf
Detailed Description	The protein tuf of Mycobacterium tuberculosis H37Ra has been reported to sequester the substrate/drug of SLC11A2, which may affects its substrate/drug distribution in the body.
Genus: Mycolicibacterium
Mycolicibacterium smegmatis	Microbe Info	Click to Show/Hide the Full List 1 Microbe Influence Related to This Species
Microbe Influence1	Sequestration of human SLC11A2 substrates/drugs in the health condition		[9], [10], [11], [12]
Regulating Factor	Mycobactin
Studied Tissue	Blood
In Vivo Model	C57BL/6 mice
Detailed Description	The compound Mycobactin Secreted by Mycolicibacterium smegmatis MC2 155 has been reported to sequester the substrate/drug of SLC11A2, which may affects its substrate/drug distribution in the body.
Mycolicibacterium vaccae	Microbe Info	Click to Show/Hide the Full List 1 Microbe Influence Related to This Species
Microbe Influence1	Sequestration of human SLC11A2 substrates/drugs in the health condition		[9], [19], [3], [4]
Regulating Factor	Exochelin 772SM
Detailed Description	The compound Exochelin 772SM Secreted by Mycolicibacterium vaccae R877R has been reported to sequester the substrate/drug of SLC11A2, which may affects its substrate/drug distribution in the body.
Bacteria: Bacillota
Genus: Bacillus
Bacillus anthracis	Microbe Info	Click to Show/Hide the Full List 4 Microbe Influence Related to This Species
Microbe Influence1	Sequestration of human SLC11A2 substrates/drugs in the health condition		[3], [4], [20], [21], [22]
Regulating Factor	Corynebactin
Detailed Description	The compound Corynebactin Secreted by Bacillus anthracis str. Sterne has been reported to sequester the substrate/drug of SLC11A2, which may affects its substrate/drug distribution in the body.
Microbe Influence2	Sequestration of human SLC11A2 substrates/drugs in the health condition		[3], [4], [20], [21], [22]
Regulating Factor	Petrobactin
Detailed Description	The compound Petrobactin Secreted by Bacillus anthracis str. Sterne has been reported to sequester the substrate/drug of SLC11A2, which may affects its substrate/drug distribution in the body.
Microbe Influence3	Sequestration of human SLC11A2 substrates/drugs in the health condition		[23], [24], [3], [4]
Regulating Factor	Petrobactin
Detailed Description	The compound Petrobactin Secreted by Bacillus anthracis str. Sterne has been reported to sequester the substrate/drug of SLC11A2, which may affects its substrate/drug distribution in the body.
Microbe Influence4	Sequestration of human SLC11A2 substrates/drugs in the health condition		[4], [5], [6], [7], [25]
Regulating Factor	mntA
Studied Tissue	Blood
In Vivo Model	ICR mice
Detailed Description	The protein mntA of Bacillus anthracis str. Vollum has been reported to sequester the substrate/drug of SLC11A2, which may affects its substrate/drug distribution in the body.
Bacillus cereus	Microbe Info	Click to Show/Hide the Full List 2 Microbe Influence Related to This Species
Microbe Influence1	Sequestration of human SLC11A2 substrates/drugs in the health condition		[3], [4], [20], [21], [22]
Regulating Factor	Corynebactin
Detailed Description	The compound Corynebactin Secreted by Bacillus cereus ATCC 14579 has been reported to sequester the substrate/drug of SLC11A2, which may affects its substrate/drug distribution in the body.
Microbe Influence2	Sequestration of human SLC11A2 substrates/drugs in the health condition		[3], [4], [20], [21], [22]
Regulating Factor	Petrobactin
Detailed Description	The compound Petrobactin Secreted by Bacillus cereus ATCC 14579 has been reported to sequester the substrate/drug of SLC11A2, which may affects its substrate/drug distribution in the body.
Bacillus thuringiensis	Microbe Info	Click to Show/Hide the Full List 1 Microbe Influence Related to This Species
Microbe Influence1	Sequestration of human SLC11A2 substrates/drugs in the health condition		[3], [4], [20], [21], [22]
Regulating Factor	Corynebactin
Detailed Description	The compound Corynebactin Secreted by Bacillus thuringiensis ATCC 33679 has been reported to sequester the substrate/drug of SLC11A2, which may affects its substrate/drug distribution in the body.
Genus: Enterococcus
Enterococcus faecalis	Microbe Info	Click to Show/Hide the Full List 1 Microbe Influence Related to This Species
Microbe Influence1	Sequestration of human SLC11A2 substrates/drugs in the health condition		[5], [6], [7], [26]
Regulating Factor	efaA
Detailed Description	The protein efaA of Enterococcus faecalis JH2-2 has been reported to sequester the substrate/drug of SLC11A2, which may affects its substrate/drug distribution in the body.
Genus: Lactiplantibacillus
Lactiplantibacillus plantarum	Microbe Info	Click to Show/Hide the Full List 1 Microbe Influence Related to This Species
Microbe Influence1	Co-transport of human SLC11A2 substrates/drugs in the health condition		[4], [5], [6], [7], [27]
Regulating Factor	mntA
Detailed Description	The protein mntA of Lactiplantibacillus plantarum subsp. plantarum ATCC 14917 has been reported to transport similar substrates/drugs of SLC11A2, which affects the distribution of its substrate/drug in vivo.
Genus: Limosilactobacillus
Limosilactobacillus reuteri	Microbe Info	Click to Show/Hide the Full List 2 Microbe Influence Related to This Species
Microbe Influence1	Down regulating of SLC11A2 expression in conventional mice compared with germ-free mice		[28], [29]
Regulating Factor	1,3-Diaminopropane
Regulation Mechanism	via suppression of Endothelial PAS domain-containing protein 1 (EPAS1)		Transcription Factor Info
Studied Phenotype	Conventional mice compared with germ-free mice [ICD11: N.A]
Studied Tissue	Duodenum
In Vivo Model	C57BL/6 germ-free mice
In Vitro Model	Human colon carcinoma cells (HCT-116)
Detailed Description	The compound 1,3-Diaminopropane Generated by Limosilactobacillus reuteri MM4-1A has been reported to decrease the expression of the drug transporter SLC11A2.
Microbe Influence2	Down regulating of SLC11A2 expression in conventional mice compared with germ-free mice		[28], [29]
Regulating Factor	3-Hydroxypropanal
Regulation Mechanism	via suppression of Endothelial PAS domain-containing protein 1 (EPAS1)		Transcription Factor Info
Studied Phenotype	Conventional mice compared with germ-free mice [ICD11: N.A]
Studied Tissue	Duodenum
In Vivo Model	C57BL/6 germ-free mice
In Vitro Model	Human colon carcinoma cells (HCT-116)
Detailed Description	The compound 3-Hydroxypropanal Generated by Limosilactobacillus reuteri MM4-1A has been reported to decrease the expression of the drug transporter SLC11A2.
Genus: Staphylococcus
Staphylococcus aureus	Microbe Info	Click to Show/Hide the Full List 17 Microbe Influence Related to This Species
Microbe Influence1	Sequestration of human SLC11A2 substrates/drugs in the health condition		[13], [30], [3], [4]
Regulating Factor	Aureochelin
Detailed Description	The compound aureochelin secreted by Staphylococcus aureus has been reported to sequester the substrate/drug of SLC11A2, which may affects its substrate/drug distribution in the body.
Microbe Influence2	Sequestration of human SLC11A2 substrates/drugs in the health condition		[20], [31], [3], [4]
Regulating Factor	Staphyloferrin A
Detailed Description	The compound Staphyloferrin A Secreted by Staphylococcus aureus subsp. aureus NCTC 8325 has been reported to sequester the substrate/drug of SLC11A2, which may affects its substrate/drug distribution in the body.
Microbe Influence3	Sequestration of human SLC11A2 substrates/drugs in the health condition		[1], [32], [3], [4]
Regulating Factor	Staphylopine
Detailed Description	The compound Staphylopine Secreted by Staphylococcus aureus RN6390 has been reported to sequester the substrate/drug of SLC11A2, which may affects its substrate/drug distribution in the body.
Microbe Influence4	Co-transport of human SLC11A2 substrates/drugs in the health condition		[5], [6], [7], [33]
Regulating Factor	MntABC , ,
Studied Tissue	Liver
In Vivo Model	C57BL/6 mice
Detailed Description	The protein MntABC of Staphylococcus aureus subsp. aureus str. Newman has been reported to transport similar substrates/drugs of SLC11A2, which affects the distribution of its substrate/drug in vivo.
Microbe Influence5	Co-transport of human SLC11A2 substrates/drugs in the health condition		[34], [35], [4]
Regulating Factor	FhuCBG , ,
Detailed Description	The protein FhuCBG of Staphylococcus aureus RN6390 has been reported to transport similar substrates/drugs of SLC11A2, which affects the distribution of its substrate/drug in vivo.
Microbe Influence6	Sequestration of human SLC11A2 substrates/drugs in the health condition		[34], [35], [4]
Regulating Factor	fhuD1
Detailed Description	The protein fhuD1 of Staphylococcus aureus RN6390 has been reported to sequester the substrate/drug of SLC11A2, which may affects its substrate/drug distribution in the body.
Microbe Influence7	Sequestration of human SLC11A2 substrates/drugs in the health condition		[34], [35], [4]
Regulating Factor	fhud2
Detailed Description	The protein fhud2 of Staphylococcus aureus RN6390 has been reported to sequester the substrate/drug of SLC11A2, which may affects its substrate/drug distribution in the body.
Microbe Influence8	Sequestration of human SLC11A2 substrates/drugs in the health condition		[1], [36], [4]
Regulating Factor	fhud2
Detailed Description	The protein fhud2 of Staphylococcus aureus RN2564 has been reported to sequester the substrate/drug of SLC11A2, which may affects its substrate/drug distribution in the body.
Microbe Influence9	Co-transport of human SLC11A2 substrates/drugs in the health condition		[34], [37], [3], [4]
Regulating Factor	HtsABC , ,
Detailed Description	The protein HtsABC of Staphylococcus aureus RN6390 has been reported to transport similar substrates/drugs of SLC11A2, which affects the distribution of its substrate/drug in vivo.
Microbe Influence10	Sequestration of human SLC11A2 substrates/drugs in the health condition		[9], [38], [3], [4]
Regulating Factor	isdA
Detailed Description	The protein isdA of Staphylococcus aureus RN6390 has been reported to sequester the substrate/drug of SLC11A2, which may affects its substrate/drug distribution in the body.
Microbe Influence11	Sequestration of human SLC11A2 substrates/drugs in the health condition		[9], [39], [3], [4]
Regulating Factor	isdA
Detailed Description	The protein isdA of Staphylococcus aureus BB has been reported to sequester the substrate/drug of SLC11A2, which may affects its substrate/drug distribution in the body.
Microbe Influence12	Sequestration of human SLC11A2 substrates/drugs in the health condition		[20], [40], [3], [4]
Regulating Factor	isdA
Detailed Description	The protein isdA of Staphylococcus aureus N100 has been reported to sequester the substrate/drug of SLC11A2, which may affects its substrate/drug distribution in the body.
Microbe Influence13	Co-transport of human SLC11A2 substrates/drugs in the health condition		[5], [6], [41], [4]
Regulating Factor	MntABC , ,
Detailed Description	The protein MntABC of Staphylococcus aureus subsp. aureus NCTC 8325 has been reported to transport similar substrates/drugs of SLC11A2, which affects the distribution of its substrate/drug in vivo.
Microbe Influence14	Co-transport of human SLC11A2 substrates/drugs in the health condition		[5], [6], [7], [41]
Regulating Factor	MntABC , ,
Detailed Description	The protein MntABC of Staphylococcus aureus subsp. aureus NCTC 8325 has been reported to transport similar substrates/drugs of SLC11A2, which affects the distribution of its substrate/drug in vivo.
Microbe Influence15	Sequestration of human SLC11A2 substrates/drugs in the health condition		[34], [37], [3], [4]
Regulating Factor	SfaABC , ,
Detailed Description	The protein SfaABC of Staphylococcus aureus RN6390 has been reported to sequester the substrate/drug of SLC11A2, which may affects its substrate/drug distribution in the body.
Microbe Influence16	Co-transport of human SLC11A2 substrates/drugs in the health condition		[34], [42], [3], [4]
Regulating Factor	SirABC , ,
Detailed Description	The protein SirABC of Staphylococcus aureus subsp. aureus RN4220 has been reported to transport similar substrates/drugs of SLC11A2, which affects the distribution of its substrate/drug in vivo.
Microbe Influence17	Co-transport of human SLC11A2 substrates/drugs in the health condition		[34], [43], [3], [4]
Regulating Factor	SstABCD , , ,
Detailed Description	The protein SstABCD of Staphylococcus aureus W has been reported to transport similar substrates/drugs of SLC11A2, which affects the distribution of its substrate/drug in vivo.
Staphylococcus capitis	Microbe Info	Click to Show/Hide the Full List 1 Microbe Influence Related to This Species
Microbe Influence1	Co-transport of human SLC11A2 substrates/drugs in the health condition		[5], [6], [7], [44]
Regulating Factor	scaDMT
Detailed Description	The protein scaDMT of Staphylococcus capitis DSM 20326 has been reported to transport similar substrates/drugs of SLC11A2, which affects the distribution of its substrate/drug in vivo.
Staphylococcus epidermidis	Microbe Info	Click to Show/Hide the Full List 2 Microbe Influence Related to This Species
Microbe Influence1	Sequestration of human SLC11A2 substrates/drugs in the health condition		[9], [39], [3], [4]
Regulating Factor	Tpn
Detailed Description	The protein tpn of Staphylococcus epidermidis 138 has been reported to sequester the substrate/drug of SLC11A2, which may affects its substrate/drug distribution in the body.
Microbe Influence2	Sequestration of human SLC11A2 substrates/drugs in the health condition		[20], [40], [3], [4]
Regulating Factor	Tpn
Detailed Description	The protein tpn of Staphylococcus epidermidis 2 has been reported to sequester the substrate/drug of SLC11A2, which may affects its substrate/drug distribution in the body.
Genus: Streptococcus
Streptococcus agalactiae	Microbe Info	Click to Show/Hide the Full List 1 Microbe Influence Related to This Species
Microbe Influence1	Co-transport of human SLC11A2 substrates/drugs in the health condition		[20], [45], [4]
Regulating Factor	FhuCDB , ,
Detailed Description	The protein FhuCDB of Streptococcus agalactiae A909 has been reported to transport similar substrates/drugs of SLC11A2, which affects the distribution of its substrate/drug in vivo.
Streptococcus equi	Microbe Info	Click to Show/Hide the Full List 2 Microbe Influence Related to This Species
Microbe Influence1	Sequestration of human SLC11A2 substrates/drugs in upper and lower airway disease condition		[46], [47], [4]
Regulating Factor	mtsB
Studied Phenotype	Upper and lower airway disease [ICD11: CA22]
Studied Tissue	Lung
In Vivo Model	Swiss Webster mice
Detailed Description	The protein mtsB of Streptococcus equi subsp. equi NCTC 9682 has been reported to sequester the substrate/drug of SLC11A2, which may affects its substrate/drug distribution in the body.
Microbe Influence2	Sequestration of human SLC11A2 substrates/drugs in the health condition		[46], [47], [4]
Regulating Factor	mtsB
Detailed Description	The protein mtsB of Streptococcus equi subsp. zooepidemicus NCTC 7023T has been reported to sequester the substrate/drug of SLC11A2, which may affects its substrate/drug distribution in the body.
Streptococcus gordonii	Microbe Info	Click to Show/Hide the Full List 2 Microbe Influence Related to This Species
Microbe Influence1	Co-transport of human SLC11A2 substrates/drugs in the health condition		[5], [6], [7], [48]
Regulating Factor	AdcRCBA , , ,
Detailed Description	The protein AdcRCBA of Streptococcus gordonii str. Challis has been reported to transport similar substrates/drugs of SLC11A2, which affects the distribution of its substrate/drug in vivo.
Microbe Influence2	Co-transport of human SLC11A2 substrates/drugs in the health condition		[5], [6], [7], [49]
Regulating Factor	ScaCBA , ,
Detailed Description	The protein ScaCBA of Streptococcus gordonii str. Challis substr. CH1 has been reported to transport similar substrates/drugs of SLC11A2, which affects the distribution of its substrate/drug in vivo.
Streptococcus mutans	Microbe Info	Click to Show/Hide the Full List 1 Microbe Influence Related to This Species
Microbe Influence1	Co-transport of human SLC11A2 substrates/drugs in endocarditis condition		[5], [6], [7], [50]
Regulating Factor	SloABC , ,
Studied Phenotype	Endocarditis [ICD11: 1B41.1]
Studied Tissue	Heart
In Vivo Model	Endocarditis rats
Detailed Description	The protein SloABC of Streptococcus mutans V403 has been reported to transport similar substrates/drugs of SLC11A2, which affects the distribution of its substrate/drug in vivo.
Streptococcus parasanguinis	Microbe Info	Click to Show/Hide the Full List 1 Microbe Influence Related to This Species
Microbe Influence1	Sequestration of human SLC11A2 substrates/drugs in the health condition		[5], [6], [7], [51]
Regulating Factor	fimA
Detailed Description	The protein fimA of Streptococcus parasanguinis FW213 has been reported to sequester the substrate/drug of SLC11A2, which may affects its substrate/drug distribution in the body.
Streptococcus pneumoniae	Microbe Info	Click to Show/Hide the Full List 2 Microbe Influence Related to This Species
Microbe Influence1	Sequestration of human SLC11A2 substrates/drugs in the health condition		[15], [6], [7], [52]
Regulating Factor	psaA
Detailed Description	The protein psaA of Streptococcus pneumoniae D39 has been reported to sequester the substrate/drug of SLC11A2, which may affects its substrate/drug distribution in the body.
Microbe Influence2	Co-transport of human SLC11A2 substrates/drugs in the health condition		[5], [6], [7], [53]
Regulating Factor	PsaABC , ,
Detailed Description	The protein PsaABC of Streptococcus pneumoniae D39 has been reported to transport similar substrates/drugs of SLC11A2, which affects the distribution of its substrate/drug in vivo.
Streptococcus pyogenes	Microbe Info	Click to Show/Hide the Full List 1 Microbe Influence Related to This Species
Microbe Influence1	Co-transport of human SLC11A2 substrates/drugs in bacterial pneumonia condition		[5], [6], [7], [54]
Regulating Factor	MtsABC , ,
Studied Phenotype	Bacterial pneumonia [ICD11: A40.0]
Studied Tissue	Lung
In Vivo Model	BALB/c mice
Detailed Description	The protein MtsABC of Streptococcus pyogenes AP1 has been reported to transport similar substrates/drugs of SLC11A2, which affects the distribution of its substrate/drug in vivo.
Streptococcus suis	Microbe Info	Click to Show/Hide the Full List 1 Microbe Influence Related to This Species
Microbe Influence1	Sequestration of human SLC11A2 substrates/drugs in sepsis condition		[5], [55], [4]
Regulating Factor	troA
Studied Phenotype	Sepsis [ICD11: 1G40-1G41]
Studied Tissue	Liver
In Vivo Model	CD-1 mice
Detailed Description	The protein troA of Streptococcus suis serotype 9 has been reported to sequester the substrate/drug of SLC11A2, which may affects its substrate/drug distribution in the body.
Bacteria: Campylobacterota
Genus: Campylobacter
Campylobacter coli	Microbe Info	Click to Show/Hide the Full List 1 Microbe Influence Related to This Species
Microbe Influence1	Sequestration of human SLC11A2 substrates/drugs in the health condition		[3], [4], [56], [57], [58]
Regulating Factor	cfrB
Detailed Description	The protein cfrB of Campylobacter coli W13A has been reported to sequester the substrate/drug of SLC11A2, which may affects its substrate/drug distribution in the body.
Campylobacter jejuni	Microbe Info	Click to Show/Hide the Full List 5 Microbe Influence Related to This Species
Microbe Influence1	Sequestration of human SLC11A2 substrates/drugs in the health condition		[3], [4], [56], [57], [59]
Regulating Factor	cfrA
Detailed Description	The protein cfrA of Campylobacter jejuni subsp. jejuni NCTC 11168 has been reported to sequester the substrate/drug of SLC11A2, which may affects its substrate/drug distribution in the body.
Microbe Influence2	Sequestration of human SLC11A2 substrates/drugs in the health condition		[3], [4], [56], [57], [58]
Regulating Factor	cfrB
Detailed Description	The protein cfrB of Campylobacter jejuni subsp. jejuni NCTC 11168 has been reported to sequester the substrate/drug of SLC11A2, which may affects its substrate/drug distribution in the body.
Microbe Influence3	Sequestration of human SLC11A2 substrates/drugs in the health condition		[3], [4], [56], [57], [60]
Regulating Factor	ctuA
Detailed Description	The protein ctuA of Campylobacter jejuni subsp. jejuni NCTC 11168 has been reported to sequester the substrate/drug of SLC11A2, which may affects its substrate/drug distribution in the body.
Microbe Influence4	Co-transport of human SLC11A2 substrates/drugs in the health condition		[56], [57], [61], [4]
Regulating Factor	feoB
Detailed Description	The protein feoB of Campylobacter jejuni subsp. jejuni NCTC 11168 has been reported to transport similar substrates/drugs of SLC11A2, which affects the distribution of its substrate/drug in vivo.
Microbe Influence5	Sequestration of human SLC11A2 substrates/drugs in the health condition		[56], [62], [4]
Regulating Factor	p19
Detailed Description	The protein p19 of Campylobacter jejuni subsp. jejuni NCTC 11168 has been reported to sequester the substrate/drug of SLC11A2, which may affects its substrate/drug distribution in the body.
Bacteria: Cyanobacteriota
Genus: Synechocystis
Synechocystis sp. PCC 6803	Microbe Info	Click to Show/Hide the Full List 4 Microbe Influence Related to This Species
Microbe Influence1	Sequestration of human SLC11A2 substrates/drugs in the health condition		[63], [64], [4]
Regulating Factor	futA1
Detailed Description	The protein futa1 of Synechocystis sp. PCC 6803 has been reported to sequester the substrate/drug of SLC11A2, which may affects its substrate/drug distribution in the body.
Microbe Influence2	Sequestration of human SLC11A2 substrates/drugs in the health condition		[63], [64], [4]
Regulating Factor	futA2
Detailed Description	The protein futa2 of Synechocystis sp. PCC 6803 has been reported to sequester the substrate/drug of SLC11A2, which may affects its substrate/drug distribution in the body.
Microbe Influence3	Sequestration of human SLC11A2 substrates/drugs in the health condition		[63], [64], [4]
Regulating Factor	futB
Detailed Description	The protein futb of Synechocystis sp. PCC 6803 has been reported to sequester the substrate/drug of SLC11A2, which may affects its substrate/drug distribution in the body.
Microbe Influence4	Sequestration of human SLC11A2 substrates/drugs in the health condition		[63], [65], [4]
Regulating Factor	sll1878
Detailed Description	The protein sll1878 of Synechocystis sp. PCC 6803 has been reported to sequester the substrate/drug of SLC11A2, which may affects its substrate/drug distribution in the body.
Bacteria: Pseudomonadota
Genus: Achromobacter
Achromobacter xylosoxidans	Microbe Info	Click to Show/Hide the Full List 1 Microbe Influence Related to This Species
Microbe Influence1	Sequestration of human SLC11A2 substrates/drugs in the health condition		[13], [3], [4]
Regulating Factor	Alcaligin
Detailed Description	The compound Alcaligin Secreted by Achromobacter xylosoxidans subsp. xylosoxydans KN 3-1 has been reported to sequester the substrate/drug of SLC11A2, which may affects its substrate/drug distribution in the body.
Genus: Acinetobacter
Acinetobacter baumannii	Microbe Info	Click to Show/Hide the Full List 1 Microbe Influence Related to This Species
Microbe Influence1	Co-transport of human SLC11A2 substrates/drugs in the health condition		[66], [3], [4]
Regulating Factor	tonB3
Detailed Description	The protein tonB3 of Acinetobacter baumannii ATCC 19606 has been reported to transport similar substrates/drugs of SLC11A2, which affects the distribution of its substrate/drug in vivo.
Genus: Bordetella
Bordetella bronchiseptica	Microbe Info	Click to Show/Hide the Full List 1 Microbe Influence Related to This Species
Microbe Influence1	Sequestration of human SLC11A2 substrates/drugs in the health condition		[13], [67], [3], [4]
Regulating Factor	Alcaligin
Detailed Description	The compound Alcaligin Secreted by Bordetella bronchiseptica B013N has been reported to sequester the substrate/drug of SLC11A2, which may affects its substrate/drug distribution in the body.
Bordetella pertussis	Microbe Info	Click to Show/Hide the Full List 1 Microbe Influence Related to This Species
Microbe Influence1	Sequestration of human SLC11A2 substrates/drugs in the health condition		[13], [67], [3], [4]
Regulating Factor	Alcaligin
Detailed Description	The compound Alcaligin Secreted by Bordetella pertussis UT25 has been reported to sequester the substrate/drug of SLC11A2, which may affects its substrate/drug distribution in the body.
Genus: Bradyrhizobium
Bradyrhizobium diazoefficiens	Microbe Info	Click to Show/Hide the Full List 1 Microbe Influence Related to This Species
Microbe Influence1	Co-transport of human SLC11A2 substrates/drugs in the health condition		[5], [68], [4]
Regulating Factor	mnoP
Detailed Description	The protein mnoP of Bradyrhizobium diazoefficiens USDA 110 has been reported to transport similar substrates/drugs of SLC11A2, which affects the distribution of its substrate/drug in vivo.
Genus: Burkholderia
Burkholderia cepacia	Microbe Info	Click to Show/Hide the Full List 3 Microbe Influence Related to This Species
Microbe Influence1	Sequestration of human SLC11A2 substrates/drugs in the health condition		[13], [69], [3], [4]
Regulating Factor	Cepabactin
Detailed Description	The compound Cepabactin Secreted by Burkholderia cepacia ATCC 25416 has been reported to sequester the substrate/drug of SLC11A2, which may affects its substrate/drug distribution in the body.
Microbe Influence2	Sequestration of human SLC11A2 substrates/drugs in the health condition		[13], [70], [3], [4]
Regulating Factor	Ornibactin
Detailed Description	The compound Ornibactin Secreted by Burkholderia cepacia TVV69 has been reported to sequester the substrate/drug of SLC11A2, which may affects its substrate/drug distribution in the body.
Microbe Influence3	Sequestration of human SLC11A2 substrates/drugs in the health condition		[13], [71], [3], [4]
Regulating Factor	Salicylic acid
Detailed Description	The compound Salicylic acid Secreted by Burkholderia cepacia Pc275c has been reported to sequester the substrate/drug of SLC11A2, which may affects its substrate/drug distribution in the body.
Genus: Escherichia
Escherichia coli	Microbe Info	Click to Show/Hide the Full List 18 Microbe Influence Related to This Species
Microbe Influence1	Sequestration of human SLC11A2 substrates/drugs in the health condition		[13], [72], [3], [4]
Regulating Factor	Aerobactin
Detailed Description	The compound Aerobactin Secreted by Escherichia coli LG1315 has been reported to sequester the substrate/drug of SLC11A2, which may affects its substrate/drug distribution in the body.
Microbe Influence2	Sequestration of human SLC11A2 substrates/drugs in the health condition		[73], [3], [4]
Regulating Factor	Enterobactin
Detailed Description	The compound Enterobactin Secreted by Escherichia coli BW25113 has been reported to sequester the substrate/drug of SLC11A2, which may affects its substrate/drug distribution in the body.
Microbe Influence3	Sequestration of human SLC11A2 substrates/drugs in the health condition		[13], [72], [3], [4]
Regulating Factor	Enterobactin
Detailed Description	The compound Enterobactin Secreted by Escherichia coli str. K-12 substr. W3110 has been reported to sequester the substrate/drug of SLC11A2, which may affects its substrate/drug distribution in the body.
Microbe Influence4	Sequestration of human SLC11A2 substrates/drugs in the health condition		[15], [74], [3], [4]
Regulating Factor	Enterobactin
Detailed Description	The compound enterobactin secreted by Escherichia coli 9.0111 has been reported to sequester the substrate/drug of SLC11A2, which may affects its substrate/drug distribution in the body.
Microbe Influence5	Sequestration of human SLC11A2 substrates/drugs in the health condition		[15], [75], [3], [4]
Regulating Factor	Enterobactin
Detailed Description	The compound Enterobactin Secreted by Escherichia coli AB33II has been reported to sequester the substrate/drug of SLC11A2, which may affects its substrate/drug distribution in the body.
Microbe Influence6	Sequestration of human SLC11A2 substrates/drugs in the health condition		[63], [76], [3], [4]
Regulating Factor	efeO
Detailed Description	The protein efeO of Escherichia coli Nissle 1917 has been reported to sequester the substrate/drug of SLC11A2, which may affects its substrate/drug distribution in the body.
Microbe Influence7	Co-transport of human SLC11A2 substrates/drugs in the health condition		[63], [77], [4]
Regulating Factor	efeU
Detailed Description	The protein efeU of Escherichia coli O157:H7 has been reported to transport similar substrates/drugs of SLC11A2, which affects the distribution of its substrate/drug in vivo.
Microbe Influence8	Co-transport of human SLC11A2 substrates/drugs in the health condition		[63], [76], [4]
Regulating Factor	efeU
Detailed Description	The protein efeU of Escherichia coli Nissle 1917 has been reported to transport similar substrates/drugs of SLC11A2, which affects the distribution of its substrate/drug in vivo.
Microbe Influence9	Co-transport of human SLC11A2 substrates/drugs in the health condition		[20], [78], [4]
Regulating Factor	fecA
Detailed Description	The protein fecA of Escherichia coli UT5600 has been reported to transport similar substrates/drugs of SLC11A2, which affects the distribution of its substrate/drug in vivo.
Microbe Influence10	Sequestration of human SLC11A2 substrates/drugs in the health condition		[20], [79], [4]
Regulating Factor	feoA
Detailed Description	The protein feoA of Escherichia coli str. K-12 substr. MC4100 has been reported to sequester the substrate/drug of SLC11A2, which may affects its substrate/drug distribution in the body.
Microbe Influence11	Co-transport of human SLC11A2 substrates/drugs in the health condition		[20], [79], [4]
Regulating Factor	feoB
Detailed Description	The protein feoB of Escherichia coli str. K-12 substr. MC4100 has been reported to transport similar substrates/drugs of SLC11A2, which affects the distribution of its substrate/drug in vivo.
Microbe Influence12	Co-transport of human SLC11A2 substrates/drugs in the health condition		[80], [81], [4]
Regulating Factor	fhuA
Detailed Description	The protein fhuA of Escherichia coli K-12 has been reported to transport similar substrates/drugs of SLC11A2, which affects the distribution of its substrate/drug in vivo.
Microbe Influence13	Co-transport of human SLC11A2 substrates/drugs in the health condition		[80], [82], [4]
Regulating Factor	fhuB
Detailed Description	The protein fhuB of Escherichia coli DH5[alpha] has been reported to transport similar substrates/drugs of SLC11A2, which affects the distribution of its substrate/drug in vivo.
Microbe Influence14	Co-transport of human SLC11A2 substrates/drugs in the health condition		[80], [83], [4]
Regulating Factor	fhuC
Detailed Description	The protein fhuC of Escherichia coli AB2847 has been reported to transport similar substrates/drugs of SLC11A2, which affects the distribution of its substrate/drug in vivo.
Microbe Influence15	Sequestration of human SLC11A2 substrates/drugs in the health condition		[80], [84], [4]
Regulating Factor	fhuD
Detailed Description	The protein fhuD of Escherichia coli BL21(DE3) has been reported to sequester the substrate/drug of SLC11A2, which may affects its substrate/drug distribution in the body.
Microbe Influence16	Co-transport of human SLC11A2 substrates/drugs in the health condition		[85], [4]
Regulating Factor	IroA , , , ,
Detailed Description	The protein IroA of Escherichia coli CFT073 has been reported to transport similar substrates/drugs of SLC11A2, which affects the distribution of its substrate/drug in vivo.
Microbe Influence17	Sequestration of human SLC11A2 substrates/drugs in the health condition		[20], [86], [3], [4]
Regulating Factor	iroN
Detailed Description	The protein iroN of Escherichia coli O18:H7 has been reported to sequester the substrate/drug of SLC11A2, which may affects its substrate/drug distribution in the body.
Microbe Influence18	Co-transport of human SLC11A2 substrates/drugs in the health condition		[5], [11], [12], [87], [88]
Regulating Factor	mntH
Detailed Description	The protein mntH of Escherichia coli EMG2 has been reported to transport similar substrates/drugs of SLC11A2, which affects the distribution of its substrate/drug in vivo.
Genus: Haemophilus
Haemophilus influenzae	Microbe Info	Click to Show/Hide the Full List 3 Microbe Influence Related to This Species
Microbe Influence1	Co-transport of human SLC11A2 substrates/drugs in the health condition		[20], [89], [4]
Regulating Factor	FhuCDB , ,
Detailed Description	The protein FhuCDB of Haemophilus influenzae R2866 has been reported to transport similar substrates/drugs of SLC11A2, which affects the distribution of its substrate/drug in vivo.
Microbe Influence2	Sequestration of human SLC11A2 substrates/drugs in the health condition		[3], [4], [9], [39], [90]
Regulating Factor	tbpA
Detailed Description	The protein tbpA of Haemophilus influenzae type b has been reported to sequester the substrate/drug of SLC11A2, which may affects its substrate/drug distribution in the body.
Microbe Influence3	Sequestration of human SLC11A2 substrates/drugs in the health condition		[3], [4], [9], [39], [90]
Regulating Factor	tbpB
Detailed Description	The protein tbpB of Haemophilus influenzae type b has been reported to sequester the substrate/drug of SLC11A2, which may affects its substrate/drug distribution in the body.
Genus: Klebsiella
Klebsiella pneumoniae	Microbe Info	Click to Show/Hide the Full List 6 Microbe Influence Related to This Species
Microbe Influence1	Sequestration of human SLC11A2 substrates/drugs in pneumonia condition		[1], [91], [3], [4]
Regulating Factor	Yersiniabactin
Studied Phenotype	Pneumonia [ICD11: CA40]
Studied Tissue	Lung
In Vivo Model	C57BL/6 mice
Detailed Description	The compound Yersiniabactin Secreted by Klebsiella pneumoniae ATCC 43816 has been reported to sequester the substrate/drug of SLC11A2, which may affects its substrate/drug distribution in the body.
Microbe Influence2	Sequestration of human SLC11A2 substrates/drugs in lung adenocarcinoma condition		[1], [92], [3], [4]
Regulating Factor	Salmochelin SX
Studied Phenotype	Lung cancer [ICD11: 2C25]
Studied Tissue	Lung
In Vitro Model	Human lung adenocarcinoma cells (A549)
Detailed Description	The compound Salmochelin SX Secreted by Klebsiella pneumoniae KP20 has been reported to sequester the substrate/drug of SLC11A2, which may affects its substrate/drug distribution in the body.
Microbe Influence3	Sequestration of human SLC11A2 substrates/drugs in the health condition		[15], [93], [3], [4]
Regulating Factor	Salmochelin SX
Studied Tissue	Lung
In Vivo Model	C57BL/6 mice
Detailed Description	The compound Salmochelin SX Secreted by Klebsiella pneumoniae KPPR1 has been reported to sequester the substrate/drug of SLC11A2, which may affects its substrate/drug distribution in the body.
Microbe Influence4	Sequestration of human SLC11A2 substrates/drugs in the health condition		[15], [93], [3], [4]
Regulating Factor	Yersiniabactin
Studied Tissue	Lung
In Vivo Model	C57BL/6 mice
Detailed Description	The compound Yersiniabactin Secreted by Klebsiella pneumoniae KPPR1 has been reported to sequester the substrate/drug of SLC11A2, which may affects its substrate/drug distribution in the body.
Microbe Influence5	Sequestration of human SLC11A2 substrates/drugs in the health condition		[15], [94], [3], [4]
Regulating Factor	Enterobactin
Detailed Description	The compound Enterobactin Secreted by Klebsiella pneumoniae 298/53 has been reported to sequester the substrate/drug of SLC11A2, which may affects its substrate/drug distribution in the body.
Microbe Influence6	Co-transport of human SLC11A2 substrates/drugs in the health condition		[63], [95], [4]
Regulating Factor	feoC
Detailed Description	The protein feoc of Klebsiella pneumoniae has been reported to transport similar substrates/drugs of SLC11A2, which affects the distribution of its substrate/drug in vivo.
Genus: Moraxella
Moraxella catarrhalis	Microbe Info	Click to Show/Hide the Full List 4 Microbe Influence Related to This Species
Microbe Influence1	Sequestration of human SLC11A2 substrates/drugs in the health condition		[1], [96], [3], [4]
Regulating Factor	lbpA
Detailed Description	The protein lbpa of Moraxella catarrhalis has been reported to sequester the substrate/drug of SLC11A2, which may affects its substrate/drug distribution in the body.
Microbe Influence2	Sequestration of human SLC11A2 substrates/drugs in the health condition		[1], [96], [3], [4]
Regulating Factor	lbpB
Detailed Description	The protein lbpb of Moraxella catarrhalis has been reported to sequester the substrate/drug of SLC11A2, which may affects its substrate/drug distribution in the body.
Microbe Influence3	Sequestration of human SLC11A2 substrates/drugs in the health condition		[1], [96], [3], [4]
Regulating Factor	tbpA
Detailed Description	The protein tbpa of Moraxella catarrhalis has been reported to sequester the substrate/drug of SLC11A2, which may affects its substrate/drug distribution in the body.
Microbe Influence4	Sequestration of human SLC11A2 substrates/drugs in the health condition		[1], [96], [3], [4]
Regulating Factor	tbpB
Detailed Description	The protein tbpb of Moraxella catarrhalis has been reported to sequester the substrate/drug of SLC11A2, which may affects its substrate/drug distribution in the body.
Genus: Morganella
Morganella morganii	Microbe Info	Click to Show/Hide the Full List 5 Microbe Influence Related to This Species
Microbe Influence1	Sequestration of human SLC11A2 substrates/drugs in the health condition		[13], [97], [3], [4]
Regulating Factor	2-Oxoadipic acid
Detailed Description	The compound 2-Oxoadipic acid Secreted by Morganella morganii SBK3 has been reported to sequester the substrate/drug of SLC11A2, which may affects its substrate/drug distribution in the body.
Microbe Influence2	Sequestration of human SLC11A2 substrates/drugs in the health condition		[13], [97], [3], [4]
Regulating Factor	3-Methyl-2-oxobutanoic acid
Detailed Description	The compound 3-Methyl-2-oxobutanoic acid Secreted by Morganella morganii SBK3 has been reported to sequester the substrate/drug of SLC11A2, which may affects its substrate/drug distribution in the body.
Microbe Influence3	Sequestration of human SLC11A2 substrates/drugs in the health condition		[13], [97], [3], [4]
Regulating Factor	4-Methyl-2-oxopentanoic acid
Detailed Description	The compound 4-Methyl-2-oxopentanoic acid Secreted by Morganella morganii SBK3 has been reported to sequester the substrate/drug of SLC11A2, which may affects its substrate/drug distribution in the body.
Microbe Influence4	Sequestration of human SLC11A2 substrates/drugs in the health condition		[13], [97], [3], [4]
Regulating Factor	Indole-3-pyruvic acid
Detailed Description	The compound Indole-3-pyruvic acid Secreted by Morganella morganii SBK3 has been reported to sequester the substrate/drug of SLC11A2, which may affects its substrate/drug distribution in the body.
Microbe Influence5	Sequestration of human SLC11A2 substrates/drugs in the health condition		[13], [97], [3], [4]
Regulating Factor	Phenylpyruvic acid
Detailed Description	The compound Phenylpyruvic acid Secreted by Morganella morganii SBK3 has been reported to sequester the substrate/drug of SLC11A2, which may affects its substrate/drug distribution in the body.
Genus: Neisseria
Neisseria gonorrhoeae	Microbe Info	Click to Show/Hide the Full List 3 Microbe Influence Related to This Species
Microbe Influence1	Sequestration of human SLC11A2 substrates/drugs in the health condition		[20], [98], [3], [4]
Regulating Factor	lbpA
Detailed Description	The protein lbpA of Neisseria gonorrhoeae FA19 has been reported to sequester the substrate/drug of SLC11A2, which may affects its substrate/drug distribution in the body.
Microbe Influence2	Sequestration of human SLC11A2 substrates/drugs in the health condition		[3], [4], [9], [39], [90]
Regulating Factor	tbpA
Detailed Description	The protein tbpa of Neisseria gonorrhoeae has been reported to sequester the substrate/drug of SLC11A2, which may affects its substrate/drug distribution in the body.
Microbe Influence3	Sequestration of human SLC11A2 substrates/drugs in the health condition		[3], [4], [9], [39], [90]
Regulating Factor	tbpB
Detailed Description	The protein tbpb of Neisseria gonorrhoeae has been reported to sequester the substrate/drug of SLC11A2, which may affects its substrate/drug distribution in the body.
Neisseria meningitidis	Microbe Info	Click to Show/Hide the Full List 2 Microbe Influence Related to This Species
Microbe Influence1	Sequestration of human SLC11A2 substrates/drugs in the health condition		[3], [4], [9], [39], [90]
Regulating Factor	tbp1
Detailed Description	The protein tbp1 of Neisseria meningitidis has been reported to sequester the substrate/drug of SLC11A2, which may affects its substrate/drug distribution in the body.
Microbe Influence2	Sequestration of human SLC11A2 substrates/drugs in the health condition		[3], [4], [9], [39], [90]
Regulating Factor	tbpB
Detailed Description	The protein tbpb of Neisseria meningitidis has been reported to sequester the substrate/drug of SLC11A2, which may affects its substrate/drug distribution in the body.
Genus: Proteus
Proteus mirabilis	Microbe Info	Click to Show/Hide the Full List 5 Microbe Influence Related to This Species
Microbe Influence1	Sequestration of human SLC11A2 substrates/drugs in the health condition		[13], [97], [3], [4]
Regulating Factor	2-Oxoadipic acid
Detailed Description	The compound 2-Oxoadipic acid Secreted by Proteus mirabilis NM 12 has been reported to sequester the substrate/drug of SLC11A2, which may affects its substrate/drug distribution in the body.
Microbe Influence2	Sequestration of human SLC11A2 substrates/drugs in the health condition		[13], [97], [3], [4]
Regulating Factor	3-Methyl-2-oxobutanoic acid
Detailed Description	The compound 3-Methyl-2-oxobutanoic acid Secreted by Proteus mirabilis NM 12 has been reported to sequester the substrate/drug of SLC11A2, which may affects its substrate/drug distribution in the body.
Microbe Influence3	Sequestration of human SLC11A2 substrates/drugs in the health condition		[13], [97], [3], [4]
Regulating Factor	4-Methyl-2-oxopentanoic acid
Detailed Description	The compound 4-Methyl-2-oxopentanoic acid Secreted by Proteus mirabilis NM 12 has been reported to sequester the substrate/drug of SLC11A2, which may affects its substrate/drug distribution in the body.
Microbe Influence4	Sequestration of human SLC11A2 substrates/drugs in the health condition		[13], [97], [3], [4]
Regulating Factor	Indole-3-pyruvic acid
Detailed Description	The compound Indole-3-pyruvic acid Secreted by Proteus mirabilis NM 12 has been reported to sequester the substrate/drug of SLC11A2, which may affects its substrate/drug distribution in the body.
Microbe Influence5	Sequestration of human SLC11A2 substrates/drugs in the health condition		[13], [97], [3], [4]
Regulating Factor	Phenylpyruvic acid
Detailed Description	The compound Phenylpyruvic acid Secreted by Proteus mirabilis NM 12 has been reported to sequester the substrate/drug of SLC11A2, which may affects its substrate/drug distribution in the body.
Proteus penneri	Microbe Info	Click to Show/Hide the Full List 5 Microbe Influence Related to This Species
Microbe Influence1	Sequestration of human SLC11A2 substrates/drugs in the health condition		[13], [97], [3], [4]
Regulating Factor	2-Oxoadipic acid
Detailed Description	The compound 2-oxoadipic acid secreted by Proteus penneri has been reported to sequester the substrate/drug of SLC11A2, which may affects its substrate/drug distribution in the body.
Microbe Influence2	Sequestration of human SLC11A2 substrates/drugs in the health condition		[13], [97], [3], [4]
Regulating Factor	3-Methyl-2-oxobutanoic acid
Detailed Description	The compound 3-methyl-2-oxobutanoic acid secreted by Proteus penneri has been reported to sequester the substrate/drug of SLC11A2, which may affects its substrate/drug distribution in the body.
Microbe Influence3	Sequestration of human SLC11A2 substrates/drugs in the health condition		[13], [97], [3], [4]
Regulating Factor	4-Methyl-2-oxopentanoic acid
Detailed Description	The compound 4-methyl-2-oxopentanoic acid secreted by Proteus penneri has been reported to sequester the substrate/drug of SLC11A2, which may affects its substrate/drug distribution in the body.
Microbe Influence4	Sequestration of human SLC11A2 substrates/drugs in the health condition		[13], [97], [3], [4]
Regulating Factor	Indole-3-pyruvic acid
Detailed Description	The compound indole-3-pyruvic acid secreted by Proteus penneri has been reported to sequester the substrate/drug of SLC11A2, which may affects its substrate/drug distribution in the body.
Microbe Influence5	Sequestration of human SLC11A2 substrates/drugs in the health condition		[13], [97], [3], [4]
Regulating Factor	Phenylpyruvic acid
Detailed Description	The compound phenylpyruvic acid secreted by Proteus penneri has been reported to sequester the substrate/drug of SLC11A2, which may affects its substrate/drug distribution in the body.
Proteus vulgaris	Microbe Info	Click to Show/Hide the Full List 5 Microbe Influence Related to This Species
Microbe Influence1	Sequestration of human SLC11A2 substrates/drugs in the health condition		[13], [97], [3], [4]
Regulating Factor	2-Oxoadipic acid
Detailed Description	The compound 2-Oxoadipic acid Secreted by Proteus vulgaris Ox 19 has been reported to sequester the substrate/drug of SLC11A2, which may affects its substrate/drug distribution in the body.
Microbe Influence2	Sequestration of human SLC11A2 substrates/drugs in the health condition		[13], [97], [3], [4]
Regulating Factor	3-Methyl-2-oxobutanoic acid
Detailed Description	The compound 3-Methyl-2-oxobutanoic acid Secreted by Proteus vulgaris Ox 19 has been reported to sequester the substrate/drug of SLC11A2, which may affects its substrate/drug distribution in the body.
Microbe Influence3	Sequestration of human SLC11A2 substrates/drugs in the health condition		[13], [97], [3], [4]
Regulating Factor	4-Methyl-2-oxopentanoic acid
Detailed Description	The compound 4-Methyl-2-oxopentanoic acid Secreted by Proteus vulgaris Ox 19 has been reported to sequester the substrate/drug of SLC11A2, which may affects its substrate/drug distribution in the body.
Microbe Influence4	Sequestration of human SLC11A2 substrates/drugs in the health condition		[13], [97], [3], [4]
Regulating Factor	Indole-3-pyruvic acid
Detailed Description	The compound Indole-3-pyruvic acid Secreted by Proteus vulgaris Ox 19 has been reported to sequester the substrate/drug of SLC11A2, which may affects its substrate/drug distribution in the body.
Microbe Influence5	Sequestration of human SLC11A2 substrates/drugs in the health condition		[13], [97], [3], [4]
Regulating Factor	Phenylpyruvic acid
Detailed Description	The compound Phenylpyruvic acid Secreted by Proteus vulgaris Ox 19 has been reported to sequester the substrate/drug of SLC11A2, which may affects its substrate/drug distribution in the body.
Genus: Providencia
Providencia alcalifaciens	Microbe Info	Click to Show/Hide the Full List 5 Microbe Influence Related to This Species
Microbe Influence1	Sequestration of human SLC11A2 substrates/drugs in the health condition		[13], [97], [3], [4]
Regulating Factor	2-Oxoadipic acid
Detailed Description	The compound 2-oxoadipic acid secreted by Providencia alcalifaciens 5487 has been reported to sequester the substrate/drug of SLC11A2, which may affects its substrate/drug distribution in the body.
Microbe Influence2	Sequestration of human SLC11A2 substrates/drugs in the health condition		[13], [97], [3], [4]
Regulating Factor	3-Methyl-2-oxobutanoic acid
Detailed Description	The compound 3-methyl-2-oxobutanoic acid secreted by Providencia alcalifaciens 5487 has been reported to sequester the substrate/drug of SLC11A2, which may affects its substrate/drug distribution in the body.
Microbe Influence3	Sequestration of human SLC11A2 substrates/drugs in the health condition		[13], [97], [3], [4]
Regulating Factor	4-Methyl-2-oxopentanoic acid
Detailed Description	The compound 4-methyl-2-oxopentanoic acid secreted by Providencia alcalifaciens 5487 has been reported to sequester the substrate/drug of SLC11A2, which may affects its substrate/drug distribution in the body.
Microbe Influence4	Sequestration of human SLC11A2 substrates/drugs in the health condition		[13], [97], [3], [4]
Regulating Factor	Indole-3-pyruvic acid
Detailed Description	The compound indole-3-pyruvic acid secreted by Providencia alcalifaciens 5487 has been reported to sequester the substrate/drug of SLC11A2, which may affects its substrate/drug distribution in the body.
Microbe Influence5	Sequestration of human SLC11A2 substrates/drugs in the health condition		[13], [97], [3], [4]
Regulating Factor	Phenylpyruvic acid
Detailed Description	The compound phenylpyruvic acid secreted by Providencia alcalifaciens 5487 has been reported to sequester the substrate/drug of SLC11A2, which may affects its substrate/drug distribution in the body.
Providencia rustigianii	Microbe Info	Click to Show/Hide the Full List 5 Microbe Influence Related to This Species
Microbe Influence1	Sequestration of human SLC11A2 substrates/drugs in the health condition		[13], [97], [3], [4]
Regulating Factor	2-Oxoadipic acid
Detailed Description	The compound 2-oxoadipic acid secreted by Providencia rustigianii 2 has been reported to sequester the substrate/drug of SLC11A2, which may affects its substrate/drug distribution in the body.
Microbe Influence2	Sequestration of human SLC11A2 substrates/drugs in the health condition		[13], [97], [3], [4]
Regulating Factor	3-Methyl-2-oxobutanoic acid
Detailed Description	The compound 3-methyl-2-oxobutanoic acid secreted by Providencia rustigianii 2 has been reported to sequester the substrate/drug of SLC11A2, which may affects its substrate/drug distribution in the body.
Microbe Influence3	Sequestration of human SLC11A2 substrates/drugs in the health condition		[13], [97], [3], [4]
Regulating Factor	4-Methyl-2-oxopentanoic acid
Detailed Description	The compound 4-methyl-2-oxopentanoic acid secreted by Providencia rustigianii 2 has been reported to sequester the substrate/drug of SLC11A2, which may affects its substrate/drug distribution in the body.
Microbe Influence4	Sequestration of human SLC11A2 substrates/drugs in the health condition		[13], [97], [3], [4]
Regulating Factor	Indole-3-pyruvic acid
Detailed Description	The compound indole-3-pyruvic acid secreted by Providencia rustigianii 2 has been reported to sequester the substrate/drug of SLC11A2, which may affects its substrate/drug distribution in the body.
Microbe Influence5	Sequestration of human SLC11A2 substrates/drugs in the health condition		[13], [97], [3], [4]
Regulating Factor	Phenylpyruvic acid
Detailed Description	The compound phenylpyruvic acid secreted by Providencia rustigianii 2 has been reported to sequester the substrate/drug of SLC11A2, which may affects its substrate/drug distribution in the body.
Providencia stuartii	Microbe Info	Click to Show/Hide the Full List 5 Microbe Influence Related to This Species
Microbe Influence1	Sequestration of human SLC11A2 substrates/drugs in the health condition		[13], [97], [3], [4]
Regulating Factor	2-Oxoadipic acid
Detailed Description	The compound 2-oxoadipic acid secreted by Providencia stuartii 19 has been reported to sequester the substrate/drug of SLC11A2, which may affects its substrate/drug distribution in the body.
Microbe Influence2	Sequestration of human SLC11A2 substrates/drugs in the health condition		[13], [97], [3], [4]
Regulating Factor	3-Methyl-2-oxobutanoic acid
Detailed Description	The compound 3-methyl-2-oxobutanoic acid secreted by Providencia stuartii 19 has been reported to sequester the substrate/drug of SLC11A2, which may affects its substrate/drug distribution in the body.
Microbe Influence3	Sequestration of human SLC11A2 substrates/drugs in the health condition		[13], [97], [3], [4]
Regulating Factor	4-Methyl-2-oxopentanoic acid
Detailed Description	The compound 4-methyl-2-oxopentanoic acid secreted by Providencia stuartii 19 has been reported to sequester the substrate/drug of SLC11A2, which may affects its substrate/drug distribution in the body.
Microbe Influence4	Sequestration of human SLC11A2 substrates/drugs in the health condition		[13], [97], [3], [4]
Regulating Factor	Indole-3-pyruvic acid
Detailed Description	The compound indole-3-pyruvic acid secreted by Providencia stuartii 19 has been reported to sequester the substrate/drug of SLC11A2, which may affects its substrate/drug distribution in the body.
Microbe Influence5	Sequestration of human SLC11A2 substrates/drugs in the health condition		[13], [97], [3], [4]
Regulating Factor	Phenylpyruvic acid
Detailed Description	The compound phenylpyruvic acid secreted by Providencia stuartii 19 has been reported to sequester the substrate/drug of SLC11A2, which may affects its substrate/drug distribution in the body.
Genus: Pseudomonas
Pseudomonas aeruginosa	Microbe Info	Click to Show/Hide the Full List 6 Microbe Influence Related to This Species
Microbe Influence1	Sequestration of human SLC11A2 substrates/drugs in cystic fibrosis condition		[99], [3], [4]
Regulating Factor	Pyochelin
Studied Phenotype	Cystic fibrosis [ICD11: CA25]
Studied Tissue	Lung
In Vivo Model	CD-1 mice
Detailed Description	The compound Pyochelin Secreted by Pseudomonas aeruginosa ATCC 15692 has been reported to sequester the substrate/drug of SLC11A2, which may affects its substrate/drug distribution in the body.
Microbe Influence2	Sequestration of human SLC11A2 substrates/drugs in cystic fibrosis condition		[99], [3], [4]
Regulating Factor	Pyoverdine F-Iib
Studied Phenotype	Cystic fibrosis [ICD11: CA25]
Studied Tissue	Lung
In Vivo Model	CD-1 mice
Detailed Description	The compound Pyoverdine F-Iib Secreted by Pseudomonas aeruginosa ATCC 15692 has been reported to sequester the substrate/drug of SLC11A2, which may affects its substrate/drug distribution in the body.
Microbe Influence3	Sequestration of human SLC11A2 substrates/drugs in the health condition		[13], [100], [3], [4]
Regulating Factor	Pyochelin
Detailed Description	The compound Pyochelin Secreted by Pseudomonas aeruginosa PAO1 has been reported to sequester the substrate/drug of SLC11A2, which may affects its substrate/drug distribution in the body.
Microbe Influence4	Sequestration of human SLC11A2 substrates/drugs in the health condition		[13], [101], [3], [4]
Regulating Factor	Pyoverdin
Detailed Description	The compound Pyoverdin Secreted by Pseudomonas aeruginosa PAO1 has been reported to sequester the substrate/drug of SLC11A2, which may affects its substrate/drug distribution in the body.
Microbe Influence5	Sequestration of human SLC11A2 substrates/drugs in the health condition		[102], [3], [4]
Regulating Factor	tonB
Detailed Description	The protein tonB of Pseudomonas aeruginosa K199 has been reported to sequester the substrate/drug of SLC11A2, which may affects its substrate/drug distribution in the body.
Microbe Influence6	Sequestration of human SLC11A2 substrates/drugs in the health condition		[103], [3], [4]
Regulating Factor	TonB1
Detailed Description	The protein TonB1 of Pseudomonas aeruginosa K1040 has been reported to sequester the substrate/drug of SLC11A2, which may affects its substrate/drug distribution in the body.
Genus: Rhizobium
Rhizobium leguminosarum	Microbe Info	Click to Show/Hide the Full List 1 Microbe Influence Related to This Species
Microbe Influence1	Co-transport of human SLC11A2 substrates/drugs in the health condition		[5], [6], [7], [104]
Regulating Factor	SitABCD , ,
Detailed Description	The protein SitABCD of Rhizobium leguminosarum bv. viciae 3841 has been reported to transport similar substrates/drugs of SLC11A2, which affects the distribution of its substrate/drug in vivo.
Genus: Salmonella
Salmonella enterica	Microbe Info	Click to Show/Hide the Full List 17 Microbe Influence Related to This Species
Microbe Influence1	Sequestration of human SLC11A2 substrates/drugs in the health condition		[15], [105], [3], [4]
Regulating Factor	Enterobactin
Studied Tissue	Intestine
In Vivo Model	C3H/HeOuJ mice
Detailed Description	The compound Enterobactin Secreted by Salmonella enterica subsp. enterica serovar Typhimurium str. 14028S has been reported to sequester the substrate/drug of SLC11A2, which may affects its substrate/drug distribution in the body.
Microbe Influence2	Sequestration of human SLC11A2 substrates/drugs in the health condition		[15], [105], [3], [4]
Regulating Factor	Salmochelin SX
Studied Tissue	Intestine
In Vivo Model	C3H/HeOuJ mice
Detailed Description	The compound Salmochelin SX Secreted by Salmonella enterica subsp. enterica serovar Typhimurium str. 14028S has been reported to sequester the substrate/drug of SLC11A2, which may affects its substrate/drug distribution in the body.
Microbe Influence3	Sequestration of human SLC11A2 substrates/drugs in the health condition		[15], [106], [3], [4]
Regulating Factor	Enterobactin
Detailed Description	The compound Enterobactin Secreted by Salmonella enterica subsp. enterica serovar Typhimurium str. LT2 has been reported to sequester the substrate/drug of SLC11A2, which may affects its substrate/drug distribution in the body.
Microbe Influence4	Sequestration of human SLC11A2 substrates/drugs in the health condition		[13], [107], [4]
Regulating Factor	Ferrioxamine B
Detailed Description	The compound Ferrioxamine B Secreted by Salmonella enterica subsp. enterica serovar Typhimurium str. ATCC 14028 has been reported to sequester the substrate/drug of SLC11A2, which may affects its substrate/drug distribution in the body.
Microbe Influence5	Sequestration of human SLC11A2 substrates/drugs in the health condition		[13], [107], [4]
Regulating Factor	Ferrioxamine E
Detailed Description	The compound Ferrioxamine E Secreted by Salmonella enterica subsp. enterica serovar Typhimurium str. ATCC 14028 has been reported to sequester the substrate/drug of SLC11A2, which may affects its substrate/drug distribution in the body.
Microbe Influence6	Sequestration of human SLC11A2 substrates/drugs in the health condition		[13], [107], [4]
Regulating Factor	Ferrioxamine G1
Detailed Description	The compound Ferrioxamine G1 Secreted by Salmonella enterica subsp. enterica serovar Typhimurium str. ATCC 14028 has been reported to sequester the substrate/drug of SLC11A2, which may affects its substrate/drug distribution in the body.
Microbe Influence7	Sequestration of human SLC11A2 substrates/drugs in the health condition		[23], [108], [3], [4]
Regulating Factor	Salmochelin SX
Detailed Description	The compound Salmochelin SX Secreted by Salmonella enterica subsp. enterica serovar Typhimurium str. LT2 has been reported to sequester the substrate/drug of SLC11A2, which may affects its substrate/drug distribution in the body.
Microbe Influence8	Co-transport of human SLC11A2 substrates/drugs in the health condition		[15], [105], [3], [4]
Regulating Factor	fepD
Studied Tissue	Intestine
In Vivo Model	C3H/HeOuJ mice
Detailed Description	The protein fepD of Salmonella enterica subsp. enterica serovar Typhimurium str. 14028S has been reported to transport similar substrates/drugs of SLC11A2, which affects the distribution of its substrate/drug in vivo.
Microbe Influence9	Co-transport of human SLC11A2 substrates/drugs in the health condition		[5], [6], [7], [33]
Regulating Factor	SitABCD , , ,
Studied Tissue	Liver
In Vivo Model	C57BL/6 mice
Detailed Description	The protein SitABCD of Salmonella enterica subsp. enterica serovar Typhimurium IR715 has been reported to transport similar substrates/drugs of SLC11A2, which affects the distribution of its substrate/drug in vivo.
Microbe Influence10	Co-transport of human SLC11A2 substrates/drugs in the health condition		[5], [6], [7], [109]
Regulating Factor	SitABCD , , ,
Studied Tissue	Blood
In Vivo Model	129/SvJ mice
Detailed Description	The protein SitABCD of Salmonella enterica subsp. enterica serovar Typhimurium has been reported to transport similar substrates/drugs of SLC11A2, which affects the distribution of its substrate/drug in vivo.
Microbe Influence11	Co-transport of human SLC11A2 substrates/drugs in the health condition		[63], [110], [4]
Regulating Factor	feoA
Detailed Description	The protein feoA of Salmonella enterica subsp. enterica serovar Typhimurium str. 14028S has been reported to transport similar substrates/drugs of SLC11A2, which affects the distribution of its substrate/drug in vivo.
Microbe Influence12	Co-transport of human SLC11A2 substrates/drugs in the health condition		[20], [111], [4]
Regulating Factor	feoB
Detailed Description	The protein feoB of Salmonella enterica subsp. enterica serovar Typhimurium str. ATCC 14028 has been reported to transport similar substrates/drugs of SLC11A2, which affects the distribution of its substrate/drug in vivo.
Microbe Influence13	Sequestration of human SLC11A2 substrates/drugs in the health condition		[63], [110], [4]
Regulating Factor	feoB
Detailed Description	The protein feoB of Salmonella enterica subsp. enterica serovar Typhimurium str. 14028S has been reported to sequester the substrate/drug of SLC11A2, which may affects its substrate/drug distribution in the body.
Microbe Influence14	Co-transport of human SLC11A2 substrates/drugs in the health condition		[63], [110], [4]
Regulating Factor	feoC
Detailed Description	The protein feoC of Salmonella enterica subsp. enterica serovar Typhimurium str. 14028S has been reported to transport similar substrates/drugs of SLC11A2, which affects the distribution of its substrate/drug in vivo.
Microbe Influence15	Co-transport of human SLC11A2 substrates/drugs in the health condition		[5], [6], [7], [87]
Regulating Factor	SitABCD , , ,
Detailed Description	The protein SitABCD of Salmonella enterica subsp. enterica serovar Typhimurium MM1255 has been reported to transport similar substrates/drugs of SLC11A2, which affects the distribution of its substrate/drug in vivo.
Microbe Influence16	Co-transport of human SLC11A2 substrates/drugs in the health condition		[15], [105], [4]
Regulating Factor	SitABCD , , ,
Detailed Description	The protein SitABCD of Salmonella enterica subsp. enterica serovar Typhimurium JF2043 has been reported to transport similar substrates/drugs of SLC11A2, which affects the distribution of its substrate/drug in vivo.
Microbe Influence17	Co-transport of human SLC11A2 substrates/drugs in the health condition		[20], [111], [3], [4]
Regulating Factor	tonB
Detailed Description	The protein tonB of Salmonella enterica subsp. enterica serovar Typhimurium str. ATCC 14028 has been reported to transport similar substrates/drugs of SLC11A2, which affects the distribution of its substrate/drug in vivo.
Genus: Serratia
Serratia marcescens	Microbe Info	Click to Show/Hide the Full List 3 Microbe Influence Related to This Species
Microbe Influence1	Sequestration of human SLC11A2 substrates/drugs in the health condition		[63], [64], [112], [4]
Regulating Factor	sfuA
Detailed Description	The protein sfua of Serratia marcescens has been reported to sequester the substrate/drug of SLC11A2, which may affects its substrate/drug distribution in the body.
Microbe Influence2	Co-transport of human SLC11A2 substrates/drugs in the health condition		[63], [64], [112], [4]
Regulating Factor	sfuB
Detailed Description	The protein sfub of Serratia marcescens has been reported to transport similar substrates/drugs of SLC11A2, which affects the distribution of its substrate/drug in vivo.
Microbe Influence3	Co-transport of human SLC11A2 substrates/drugs in the health condition		[63], [64], [112], [4]
Regulating Factor	sfuC
Detailed Description	The protein sfuc of Serratia marcescens has been reported to transport similar substrates/drugs of SLC11A2, which affects the distribution of its substrate/drug in vivo.
Genus: Shigella
Shigella flexneri	Microbe Info	Click to Show/Hide the Full List 6 Microbe Influence Related to This Species
Microbe Influence1	Sequestration of human SLC11A2 substrates/drugs in the health condition		[20], [113], [4]
Regulating Factor	fec
Detailed Description	The protein fec of Shigella flexneri 2a has been reported to sequester the substrate/drug of SLC11A2, which may affects its substrate/drug distribution in the body.
Microbe Influence2	Co-transport of human SLC11A2 substrates/drugs in the health condition		[20], [114], [4]
Regulating Factor	feoB
Detailed Description	The protein feoB of Shigella flexneri SA100 has been reported to transport similar substrates/drugs of SLC11A2, which affects the distribution of its substrate/drug in vivo.
Microbe Influence3	Co-transport of human SLC11A2 substrates/drugs in the health condition		[20], [114], [4]
Regulating Factor	sitA
Detailed Description	The protein sitA of Shigella flexneri SA100 has been reported to transport similar substrates/drugs of SLC11A2, which affects the distribution of its substrate/drug in vivo.
Microbe Influence4	Co-transport of human SLC11A2 substrates/drugs in the health condition		[20], [6], [7], [114]
Regulating Factor	sitA
Detailed Description	The protein sitA of Shigella flexneri SA100 has been reported to transport similar substrates/drugs of SLC11A2, which affects the distribution of its substrate/drug in vivo.
Microbe Influence5	Co-transport of human SLC11A2 substrates/drugs in the health condition		[5], [6], [114], [4]
Regulating Factor	SitABCD , , ,
Detailed Description	The protein SitABCD of Shigella flexneri SA100 has been reported to transport similar substrates/drugs of SLC11A2, which affects the distribution of its substrate/drug in vivo.
Microbe Influence6	Co-transport of human SLC11A2 substrates/drugs in the health condition		[5], [6], [7], [114]
Regulating Factor	SitABCD , , ,
Detailed Description	The protein SitABCD of Shigella flexneri SA100 has been reported to transport similar substrates/drugs of SLC11A2, which affects the distribution of its substrate/drug in vivo.
Shigella sonnei	Microbe Info	Click to Show/Hide the Full List 1 Microbe Influence Related to This Species
Microbe Influence1	Sequestration of human SLC11A2 substrates/drugs in the health condition		[15], [94], [3], [4]
Regulating Factor	Enterobactin
Detailed Description	The compound Enterobactin Secreted by Shigella sonnei 43-GG9 has been reported to sequester the substrate/drug of SLC11A2, which may affects its substrate/drug distribution in the body.
Genus: Sinorhizobium
Sinorhizobium meliloti	Microbe Info	Click to Show/Hide the Full List 1 Microbe Influence Related to This Species
Microbe Influence1	Co-transport of human SLC11A2 substrates/drugs in the health condition		[5], [6], [7], [115]
Regulating Factor	MntABC , ,
Detailed Description	The protein mntabc of Sinorhizobium meliloti 242 has been reported to transport similar substrates/drugs of SLC11A2, which affects the distribution of its substrate/drug in vivo.
Genus: Vibrio
Vibrio anguillarum	Microbe Info	Click to Show/Hide the Full List 3 Microbe Influence Related to This Species
Microbe Influence1	Sequestration of human SLC11A2 substrates/drugs in the health condition		[13], [116], [3], [4]
Regulating Factor	Anguibactin
Detailed Description	The compound anguibactin secreted by Vibrio anguillarum 775 has been reported to sequester the substrate/drug of SLC11A2, which may affects its substrate/drug distribution in the body.
Microbe Influence2	Co-transport of human SLC11A2 substrates/drugs in the health condition		[13], [116], [4]
Regulating Factor	fatA
Detailed Description	The protein fata of Vibrio anguillarum 775 has been reported to transport similar substrates/drugs of SLC11A2, which affects the distribution of its substrate/drug in vivo.
Microbe Influence3	Co-transport of human SLC11A2 substrates/drugs in the health condition		[13], [116], [4]
Regulating Factor	fatB
Detailed Description	The protein fatb of Vibrio anguillarum 775 has been reported to transport similar substrates/drugs of SLC11A2, which affects the distribution of its substrate/drug in vivo.
Vibrio cholerae	Microbe Info	Click to Show/Hide the Full List 6 Microbe Influence Related to This Species
Microbe Influence1	Sequestration of human SLC11A2 substrates/drugs in the health condition		[20], [117], [3], [4]
Regulating Factor	Vibriobactin
Detailed Description	The compound Vibriobactin Secreted by Vibrio cholerae Lou15 has been reported to sequester the substrate/drug of SLC11A2, which may affects its substrate/drug distribution in the body.
Microbe Influence2	Sequestration of human SLC11A2 substrates/drugs in the health condition		[13], [118], [3], [4]
Regulating Factor	Vibriobactin
Detailed Description	The compound Vibriobactin Secreted by Vibrio cholerae MBG14 has been reported to sequester the substrate/drug of SLC11A2, which may affects its substrate/drug distribution in the body.
Microbe Influence3	Co-transport of human SLC11A2 substrates/drugs in cholera condition		[6], [7], [119]
Regulating Factor	ZnuABC , ,
Studied Phenotype	Cholera [ICD11: 1A00]
Studied Tissue	Small intestine
In Vivo Model	CD-1 mice
Detailed Description	The protein ZnuABC of Vibrio cholerae C6706 has been reported to transport similar substrates/drugs of SLC11A2, which affects the distribution of its substrate/drug in vivo.
Microbe Influence4	Co-transport of human SLC11A2 substrates/drugs in cholera condition		[6], [7], [119]
Regulating Factor	ZrgABCDE , , , ,
Studied Phenotype	Cholera [ICD11: 1A00]
Studied Tissue	Small intestine
In Vivo Model	CD-1 mice
Detailed Description	The protein ZrgABCDE of Vibrio cholerae C6706 has been reported to transport similar substrates/drugs of SLC11A2, which affects the distribution of its substrate/drug in vivo.
Microbe Influence5	Co-transport of human SLC11A2 substrates/drugs in the health condition		[20], [120], [4]
Regulating Factor	Fbp
Detailed Description	The protein Fbp of Vibrio cholerae O395 has been reported to transport similar substrates/drugs of SLC11A2, which affects the distribution of its substrate/drug in vivo.
Microbe Influence6	Co-transport of human SLC11A2 substrates/drugs in the health condition		[20], [120], [4]
Regulating Factor	feo
Detailed Description	The protein feo of Vibrio cholerae O395 has been reported to transport similar substrates/drugs of SLC11A2, which affects the distribution of its substrate/drug in vivo.
Genus: Yersinia
Yersinia enterocolitica	Microbe Info	Click to Show/Hide the Full List 2 Microbe Influence Related to This Species
Microbe Influence1	Sequestration of human SLC11A2 substrates/drugs in the health condition		[13], [121], [3], [4]
Regulating Factor	Yersiniabactin
Detailed Description	The compound Yersiniabactin Secreted by Yersinia enterocolitica WA-C has been reported to sequester the substrate/drug of SLC11A2, which may affects its substrate/drug distribution in the body.
Microbe Influence2	Sequestration of human SLC11A2 substrates/drugs in the health condition		[13], [121], [4]
Regulating Factor	fyuA
Detailed Description	The protein fyuA of Yersinia enterocolitica WA-C has been reported to sequester the substrate/drug of SLC11A2, which may affects its substrate/drug distribution in the body.
Yersinia pestis	Microbe Info	Click to Show/Hide the Full List 11 Microbe Influence Related to This Species
Microbe Influence1	Sequestration of human SLC11A2 substrates/drugs in the health condition		[13], [122], [3], [4]
Regulating Factor	Yersiniabactin
Detailed Description	The compound Yersiniabactin Secreted by Yersinia pestis Yreka F1+VW+P1+P+ has been reported to sequester the substrate/drug of SLC11A2, which may affects its substrate/drug distribution in the body.
Microbe Influence2	Co-transport of human SLC11A2 substrates/drugs in pneumonic plague condition		[123], [4]
Regulating Factor	feo
Studied Phenotype	Pneumonic plague [ICD11: 1B93.2]
Studied Tissue	Lung
In Vivo Model	Swiss Webster mice
Detailed Description	The protein feo of Yersinia pestis KIM6 has been reported to transport similar substrates/drugs of SLC11A2, which affects the distribution of its substrate/drug in vivo.
Microbe Influence3	Co-transport of human SLC11A2 substrates/drugs in pneumonic plague condition		[5], [6], [7], [123]
Regulating Factor	yfeA
Studied Phenotype	Pneumonic plague [ICD11: 1B93.2]
Studied Tissue	Nose
In Vivo Model	Swiss Webster mice
Detailed Description	The protein yfeA of Yersinia pestis KIM6 has been reported to transport similar substrates/drugs of SLC11A2, which affects the distribution of its substrate/drug in vivo.
Microbe Influence4	Co-transport of human SLC11A2 substrates/drugs in pneumonic plague condition		[5], [6], [7], [124]
Regulating Factor	YfeABCD , , ,
Studied Phenotype	Pneumonic plague [ICD11: 1B93.2]
Studied Tissue	Nose
In Vivo Model	Swiss Webster mice
Detailed Description	The protein yfeabcd of Yersinia pestis has been reported to transport similar substrates/drugs of SLC11A2, which affects the distribution of its substrate/drug in vivo.
Microbe Influence5	Co-transport of human SLC11A2 substrates/drugs in pneumonic plague condition		[5], [6], [7], [124]
Regulating Factor	YfeABCD , , ,
Studied Phenotype	Pneumonic plague [ICD11: 1B93.2]
Studied Tissue	Nose
In Vivo Model	Swiss Webster mice
Detailed Description	The protein YfeABCD of Yersinia pestis KIM6 has been reported to transport similar substrates/drugs of SLC11A2, which affects the distribution of its substrate/drug in vivo.
Microbe Influence6	Sequestration of human SLC11A2 substrates/drugs in the health condition		[20], [125], [3], [4]
Regulating Factor	irp2
Studied Tissue	Lung
In Vivo Model	Swiss Webster mice
Detailed Description	The protein irp2 of Yersinia pestis KIM5 has been reported to sequester the substrate/drug of SLC11A2, which may affects its substrate/drug distribution in the body.
Microbe Influence7	Sequestration of human SLC11A2 substrates/drugs in the health condition		[20], [125], [4]
Regulating Factor	psn
Studied Tissue	Lung
In Vivo Model	Swiss Webster mice
Detailed Description	The protein psn of Yersinia pestis KIM5 has been reported to sequester the substrate/drug of SLC11A2, which may affects its substrate/drug distribution in the body.
Microbe Influence8	Co-transport of human SLC11A2 substrates/drugs in the health condition		[20], [126], [4]
Regulating Factor	YfeAB ,
Studied Tissue	Blood
In Vivo Model	Swiss Webster mice
Detailed Description	The protein YfeAB of Yersinia pestis KIM5 has been reported to transport similar substrates/drugs of SLC11A2, which affects the distribution of its substrate/drug in vivo.
Microbe Influence9	Co-transport of human SLC11A2 substrates/drugs in the health condition		[123], [4]
Regulating Factor	YfeABCD , , ,
Studied Tissue	Lung
In Vivo Model	Swiss Webster mice
Detailed Description	The protein YfeABCD of Yersinia pestis KIM6 has been reported to transport similar substrates/drugs of SLC11A2, which affects the distribution of its substrate/drug in vivo.
Microbe Influence10	Co-transport of human SLC11A2 substrates/drugs in the health condition		[5], [6], [126], [4]
Regulating Factor	YfeABCD , , ,
Detailed Description	The protein YfeABCD of Yersinia pestis KIM5-2031.11+ has been reported to transport similar substrates/drugs of SLC11A2, which affects the distribution of its substrate/drug in vivo.
Microbe Influence11	Co-transport of human SLC11A2 substrates/drugs in the health condition		[5], [6], [7], [126]
Regulating Factor	YfeABCD , , ,
Detailed Description	The protein YfeABCD of Yersinia pestis KIM5-2031.11+ has been reported to transport similar substrates/drugs of SLC11A2, which affects the distribution of its substrate/drug in vivo.
Yersinia pseudotuberculosis	Microbe Info	Click to Show/Hide the Full List 1 Microbe Influence Related to This Species
Microbe Influence1	Sequestration of human SLC11A2 substrates/drugs in the health condition		[127], [4]
Regulating Factor	tssS
Detailed Description	The protein tssS of Yersinia pseudotuberculosis YPIII has been reported to sequester the substrate/drug of SLC11A2, which may affects its substrate/drug distribution in the body.
Bacteria: Spirochaetota
Genus: Treponema
Treponema pallidum	Microbe Info	Click to Show/Hide the Full List 2 Microbe Influence Related to This Species
Microbe Influence1	Sequestration of human SLC11A2 substrates/drugs in the health condition		[128], [4]
Regulating Factor	troA
Detailed Description	The protein troA of Treponema pallidum subsp. pallidum str. Nichols has been reported to sequester the substrate/drug of SLC11A2, which may affects its substrate/drug distribution in the body.
Microbe Influence2	Sequestration of human SLC11A2 substrates/drugs in the health condition		[128], [3], [4]
Regulating Factor	troA
Detailed Description	The protein troA of Treponema pallidum subsp. pallidum str. Nichols has been reported to sequester the substrate/drug of SLC11A2, which may affects its substrate/drug distribution in the body.
Fungi: Ascomycota
Genus: Candida
Candida albicans	Microbe Info	Click to Show/Hide the Full List 2 Microbe Influence Related to This Species
Microbe Influence1	Co-transport of human SLC11A2 substrates/drugs in the health condition		[15], [93], [3], [4]
Regulating Factor	Sit1p
Studied Tissue	Blood
In Vivo Model	BALB/c mice
Detailed Description	The protein Sit1p of Candida albicans CAF2-1 has been reported to transport similar substrates/drugs of SLC11A2, which affects the distribution of its substrate/drug in vivo.
Microbe Influence2	Co-transport of human SLC11A2 substrates/drugs in the health condition		[15], [129], [4]
Regulating Factor	CaFTR1
Detailed Description	The protein caftr1 of Candida albicans has been reported to transport similar substrates/drugs of SLC11A2, which affects the distribution of its substrate/drug in vivo.
Fungi: Mucoromycota
Genus: Rhizopus
Rhizopus microsporus	Microbe Info	Click to Show/Hide the Full List 1 Microbe Influence Related to This Species
Microbe Influence1	Sequestration of human SLC11A2 substrates/drugs in the health condition		[1], [130], [3], [4]
Regulating Factor	Rhizoferrin
Detailed Description	The compound rhizoferrin secreted by Rhizopus microsporus has been reported to sequester the substrate/drug of SLC11A2, which may affects its substrate/drug distribution in the body.
Bacteria: Host unspecified microbiota
Genus: Unknown microbiota
Host unspecified microbiota		Click to Show/Hide the Full List 6 Microbe Influence Related to This Species
Microbe Influence1	Up regulating of SLC11A2 expression in anemia condition		[131]
Regulating Factor	Short-chain fatty acid (Acetate)
Studied Phenotype	Anemia [ICD11: 3A01.30]
Studied Tissue	Colon
In Vivo Model	Yorkshire-Hampshire-Landrace hybrid pigs
Detailed Description	The metabolite short-chain fatty acid (acetate) generated from the metabolism of dietary inulin by the host unspecified microbiota has been reported to increase the expression of the drug transporter SLC11A2.
Microbe Influence2	Up regulating of SLC11A2 expression in anemia condition		[131]
Regulating Factor	Short-chain fatty acid (Acetate)
Studied Phenotype	Anemia [ICD11: 3A01.30]
Studied Tissue	Duodenum
In Vivo Model	Yorkshire-Hampshire-Landrace hybrid pigs
Detailed Description	The metabolite short-chain fatty acid (acetate) generated from the metabolism of dietary inulin by the host unspecified microbiota has been reported to increase the expression of the drug transporter SLC11A2.
Microbe Influence3	Up regulating of SLC11A2 expression in anemia condition		[131]
Regulating Factor	Short-chain fatty acid (Butyrate)
Studied Phenotype	Anemia [ICD11: 3A01.30]
Studied Tissue	Colon
In Vivo Model	Yorkshire-Hampshire-Landrace hybrid pigs
Detailed Description	The metabolite short-chain fatty acid (butyrate) generated from the metabolism of dietary inulin by the host unspecified microbiota has been reported to increase the expression of the drug transporter SLC11A2.
Microbe Influence4	Up regulating of SLC11A2 expression in anemia condition		[131]
Regulating Factor	Short-chain fatty acid (Butyrate)
Studied Phenotype	Anemia [ICD11: 3A01.30]
Studied Tissue	Duodenum
In Vivo Model	Yorkshire-Hampshire-Landrace hybrid pigs
Detailed Description	The metabolite short-chain fatty acid (butyrate) generated from the metabolism of dietary inulin by the host unspecified microbiota has been reported to increase the expression of the drug transporter SLC11A2.
Microbe Influence5	Up regulating of SLC11A2 expression in anemia condition		[131]
Regulating Factor	Short-chain fatty acid (Propionate)
Studied Phenotype	Anemia [ICD11: 3A01.30]
Studied Tissue	Colon
In Vivo Model	Yorkshire-Hampshire-Landrace hybrid pigs
Detailed Description	The metabolite short-chain fatty acid (propionate) generated from the metabolism of dietary inulin by the host unspecified microbiota has been reported to increase the expression of the drug transporter SLC11A2.
Microbe Influence6	Up regulating of SLC11A2 expression in anemia condition		[131]
Regulating Factor	Short-chain fatty acid (Propionate)
Studied Phenotype	Anemia [ICD11: 3A01.30]
Studied Tissue	Duodenum
In Vivo Model	Yorkshire-Hampshire-Landrace hybrid pigs
Detailed Description	The metabolite short-chain fatty acid (propionate) generated from the metabolism of dietary inulin by the host unspecified microbiota has been reported to increase the expression of the drug transporter SLC11A2.

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