Microbe Species Information | VARIDT

General Information of This Microbe species
Species ID	MIC00062
Species Name	Pseudomonas aeruginosa
Taxonomy ID	287
Lineage	Kingdom:Bacteria Phylum:Pseudomonadota Class:Gammaproteobacteria Order:Pseudomonadales Family:Pseudomonadaceae Genus: Pseudomonas Species: Pseudomonas aeruginosa

Drug Transporter(s) Regulated by This Microbe species
Class1: Microbiota direct bioaccumulation of drugs
ATP7A	Transporter Info	Health [ICD11: N.A]			[1], [2], [3], [4]
ATP7B	Transporter Info	Health [ICD11: N.A]			[1], [2], [3], [4]
CACNA1A	Transporter Info	Cystic fibrosis [ICD11: CA25]			[5], [6], [7]
COPT2	Transporter Info	Health [ICD11: N.A]			[1], [2], [4], [8]
CTR1	Transporter Info	Health [ICD11: N.A]			[1], [2], [4], [8]
IREG1	Transporter Info	Health [ICD11: N.A]			[9], [6], [7]
NRAMP2	Transporter Info	Cystic fibrosis [ICD11: CA25]			[5], [6], [7]
SLC25A28	Transporter Info	Health [ICD11: N.A]			[9], [6], [7]
SLC25A37	Transporter Info	Health [ICD11: N.A]			[10], [6], [7]
ZIP14	Transporter Info	Cystic fibrosis [ICD11: CA25]			[5], [6], [7]
ZIP8	Transporter Info	Cystic fibrosis [ICD11: CA25]			[5], [6], [7]

Species Relative Abundances of This Microbe species

References
1	Trace metals and animal health: Interplay of the gut microbiota with iron, manganese, zinc, and copper. Anim Nutr. 2021 Sep;7(3):750-761.
2	Cu Homeostasis in Bacteria: The Ins and Outs. Membranes (Basel). 2020 Sep 18;10(9):242.
3	The interplay of the metallosensor CueR with two distinct CopZ chaperones defines copper homeostasis in Pseudomonas aeruginosa. J Biol Chem. 2019 Mar 29;294(13):4934-4945.
4	Human copper transporters: mechanism, role in human diseases and therapeutic potential. Future Med Chem. 2009 Sep;1(6):1125-42.
5	Role of Iron Uptake Systems in Pseudomonas aeruginosa Virulence and Airway Infection. Infect Immun. 2016 Jul 21;84(8):2324-2335.
6	Iron, copper, zinc, and manganese transport and regulation in pathogenic Enterobacteria: correlations between strains, site of infection and the relative importance of the different metal transport systems for virulence. Front Cell Infect Microbiol. 2013 Dec 5;3:90.
7	Iron and manganese transport in mammalian systems. Biochim Biophys Acta Mol Cell Res. 2021 Jan;1868(1):118890.
8	Protein C (OprC) of the outer membrane of Pseudomonas aeruginosa is a copper-regulated channel protein. Microbiology (Reading). 1996 Aug;142 ( Pt 8):2137-44.
9	The Pseudomonas aeruginosa tonB gene encodes a novel TonB protein. Microbiology (Reading). 1996 Jun;142 ( Pt 6):1449-1458.
10	Mutational analysis of the TonB1 energy coupler of Pseudomonas aeruginosa. J Bacteriol. 2002 Mar;184(6):1503-13.

If you find any error in data or bug in web service, please kindly report it to Dr. Li and Dr. Fu.