Microbe Species Information

General Information of This Microbe species
Species ID	MIC00016
Species Name	Campylobacter jejuni
Taxonomy ID	197
Lineage	Kingdom:Bacteria Phylum:Campylobacterota Class:Epsilonproteobacteria Order:Campylobacterales Family:Campylobacteraceae Genus: Campylobacter Species: Campylobacter jejuni

Drug Transporter(s) Regulated by This Microbe species
Class1: Microbiota direct bioaccumulation of drugs
CACNA1A	Transporter Info	Health [ICD11: N.A]	[1], [2], [3], [4]
COPT2	Transporter Info	Health [ICD11: N.A]	[1], [5], [6], [7]
CTR1	Transporter Info	Health [ICD11: N.A]	[1], [5], [6], [7]
FLVCR1	Transporter Info	Health [ICD11: N.A]	[1], [2], [8], [9], [10]
IREG1	Transporter Info	Health [ICD11: N.A]	[1], [5], [4]
NRAMP2	Transporter Info	Health [ICD11: N.A]	[1], [5], [4]
SLC25A28	Transporter Info	Health [ICD11: N.A]	[1], [5], [4]
SLC25A37	Transporter Info	Health [ICD11: N.A]	[1], [5], [4]
SLC48A1	Transporter Info	Health [ICD11: N.A]	[1], [2], [8], [9], [10]
SLC49A2	Transporter Info	Health [ICD11: N.A]	[1], [2], [8], [9], [10]
ZIP1	Transporter Info	Gastroenteritis [ICD11: 1A40]	[11], [12], [13], [14]
ZIP10	Transporter Info	Gastroenteritis [ICD11: 1A40]	[11], [12], [13], [14]
ZIP11	Transporter Info	Gastroenteritis [ICD11: 1A40]	[11], [12], [13], [14]
ZIP12	Transporter Info	Gastroenteritis [ICD11: 1A40]	[11], [12], [13], [14]
ZIP13	Transporter Info	Gastroenteritis [ICD11: 1A40]	[11], [12], [13], [14]
ZIP14	Transporter Info	Health [ICD11: N.A]	[1], [5], [4]
ZIP2	Transporter Info	Gastroenteritis [ICD11: 1A40]	[11], [12], [13], [14]
ZIP3	Transporter Info	Gastroenteritis [ICD11: 1A40]	[11], [12], [13], [14]
ZIP4	Transporter Info	Gastroenteritis [ICD11: 1A40]	[11], [12], [13], [14]
ZIP5	Transporter Info	Gastroenteritis [ICD11: 1A40]	[11], [12], [13], [14]
ZIP6	Transporter Info	Gastroenteritis [ICD11: 1A40]	[11], [12], [13], [14]
ZIP7	Transporter Info	Gastroenteritis [ICD11: 1A40]	[11], [12], [13], [14]
ZIP8	Transporter Info	Health [ICD11: N.A]	[1], [5], [4]
ZIP9	Transporter Info	Gastroenteritis [ICD11: 1A40]	[11], [12], [13], [14]

Species Relative Abundances of This Microbe species

References
1	Metal homeostasis in pathogenic Epsilonproteobacteria: mechanisms of acquisition, efflux, and regulation. Metallomics. 2021 Jan 16;13(1):mfaa002.
2	Nutrient acquisition and metabolism by Campylobacter jejuni. Front Cell Infect Microbiol. 2012 Feb 7;2:5.
3	Major role for FeoB in Campylobacter jejuni ferrous iron acquisition, gut colonization, and intracellular survival. Infect Immun. 2006 Oct;74(10):5433-44.
4	Iron and manganese transport in mammalian systems. Biochim Biophys Acta Mol Cell Res. 2021 Jan;1868(1):118890.
5	Structure and function of P19, a high-affinity iron transporter of the human pathogen Campylobacter jejuni. J Mol Biol. 2010 Aug 27;401(4):590-604.
6	Cu Homeostasis in Bacteria: The Ins and Outs. Membranes (Basel). 2020 Sep 18;10(9):242.
7	Human copper transporters: mechanism, role in human diseases and therapeutic potential. Future Med Chem. 2009 Sep;1(6):1125-42.
8	Heme utilization in Campylobacter jejuni. J Bacteriol. 2006 Nov;188(22):7862-75.
9	Heme Mobilization in Animals: A Metallolipid's Journey. Acc Chem Res. 2016 Jun 21;49(6):1104-10.
10	Handling heme: The mechanisms underlying the movement of heme within and between cells. Free Radic Biol Med. 2019 Mar;133:88-100.
11	Transition metal ions at the crossroads of mucosal immunity and microbial pathogenesis. Front Cell Infect Microbiol. 2014 Jan 24;4:2.
12	A Campylobacter jejuni znuA orthologue is essential for growth in low-zinc environments and chick colonization. J Bacteriol. 2009 Mar;191(5):1631-40.
13	Zinc competition among the intestinal microbiota. mBio. 2012 Jul 31;3(4):e00171-12.
14	Transition metals and host-microbe interactions in the inflamed intestine. Biometals. 2019 Jun;32(3):369-384.

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