Modelled DT Structure
Method: multi-sequence alignment based machine learning
Detail: Structure Info
Drug Transporter (DT) Information
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| General Information of DT | |||||
|---|---|---|---|---|---|
| DT ID | DTD0377 | ||||
| Gene Name | SLC49A2 | ||||
| Protein Name | Feline leukemia virus subgroup C receptor-related protein 2 | ||||
| Gene ID | |||||
| UniProt ID | |||||
| TCDB ID | |||||
| 3D Structure |
Modelled DT Structure Method: multi-sequence alignment based machine learning Detail: Structure Info |
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| Synonyms | C14orf58; CCT; Calcium-chelate transporter; EPV; FLVCR2; FLVCRL14q; MFSD7C; PVHH; SLC49A2 | ||||
| DT Family | Major Facilitator Superfamily (MFS) | ||||
| Feline Leukemia Virus Subgroup C Receptor (FLVCR)/Heme Importer Family | |||||
| Function | This transporter mediates the import of heme and also acts as a transporter for a calcium-chelator complex, important for growth and calcium metabolism. | ||||
| Endogenous Substrate(s) | Heme | ||||
| Variability Data of This Drug Transporter (DT) | |||||
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Regulatory Variability Data of This DT (VARIDT 4.0) |
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(α) Tissue Distribution Level of Feline leukemia virus subgroup C receptor-related protein 2 |
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(β) Cell Distribution Level of Feline leukemia virus subgroup C receptor-related protein 2 |
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(γ) Organelle Distribution Level of Feline leukemia virus subgroup C receptor-related protein 2 |
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Regulatory Variability Data of This DT |
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(α) Microbiota Influence of Feline leukemia virus subgroup C receptor-related protein 2 |
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(β) Post-translational Modification of Feline leukemia virus subgroup C receptor-related protein 2 |
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(δ) Epigenetic Regulation of Feline leukemia virus subgroup C receptor-related protein 2 |
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(ε) Exogenous Modulation of Feline leukemia virus subgroup C receptor-related protein 2 |
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Structural Variability Data of This DT |
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(γ) Outward/inward-facing Conformation |
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General Variability Data of This DT |
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(α) Genetic Polymorphisms of Feline leukemia virus subgroup C receptor-related protein 2 |
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(β) Disease-specific Protein Abundances of Feline leukemia virus subgroup C receptor-related protein 2 |
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(γ) Species- and Tissue-specific DT Abundances |
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If you find any error in data or bug in web service, please kindly report it to Dr. Li and Dr. Fu.