Drug Transporter (DT) Information

General Information of DT
DT ID DTD0338
Gene Name SLC39A10
Protein Name Zinc transporter ZIP10
Gene ID
57181
UniProt ID
Q9ULF5
TCDB ID
2.A.5.4.6
3D Structure

Modelled DT Structure

Method: multi-sequence alignment based machine learning

Detail: Structure Info

Synonyms KIAA1265; LZT-Hs2; SLC39A10; Solute carrier family 39 member 10; ZIP-10; ZIP10; Zinc transporter ZIP10
DT Family Zinc (Zn(2+))-Iron (Fe(2+)) Permease (ZIP) Family ;
Function This transporter may act as a zinc-influx transporter.
Endogenous Substrate(s) Zn2+
Variability Data of This Drug Transporter (DT)

Regulatory Variability Data of This DT (VARIDT 4.0)

(α) Tissue Distribution Level of Zinc transporter ZIP10
Tissue Distribution Level (TD)

(β) Cell Distribution Level of Zinc transporter ZIP10
Cell Distribution Level (CD)

(γ) Organelle Distribution Level of Zinc transporter ZIP10
Organelle Distribution Level (Subc)

Regulatory Variability Data of This DT

(α) Microbiota Influence of Zinc transporter ZIP10
Microbiota Influence (MBI)

(β) Post-translational Modification of Zinc transporter ZIP10
Post-translational Modification (PTM)

(γ) Transcriptional Regulation of Zinc transporter ZIP10
Transcriptional Regulation (TSR)

(δ) Epigenetic Regulation of Zinc transporter ZIP10
Epigenetic Regulation (EGR)

(ε) Exogenous Modulation of Zinc transporter ZIP10
Exogenous Modulation (EGM)

General Variability Data of This DT

(α) Genetic Polymorphisms of Zinc transporter ZIP10
Genetic Polymorphisms of This DT (GPD)

(β) Disease-specific Protein Abundances of Zinc transporter ZIP10
Disease-specific Protein Abundances of This DT (DPAD)

(γ) Species- and Tissue-specific DT Abundances
Species/Tissue-specific Protein Abundances of This DT (S/TPAD)
Molecular Transporting Profile of This DT

Full List of Drug(s) Transported by This DT

 Withdrawn, Discontinued or Preclinical Drug

 Click to Show/Hide the Full List of Drug:           1 Drugs in Total
Drug Name Highest Status Detail Indication ICD 11 Ref
Zinc salts
 Preclinical Drug Info Arthritis FA5Z [1]
References
1 Zinc transporter SLC39A10/ZIP10 facilitates antiapoptotic signaling during early B-cell development. Proc Natl Acad Sci U S A. 2014 Aug 12;111(32):11780-5.

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