Detail Information of Exogenous Modulation
General Information of Drug Transporter (DT) | |||||
---|---|---|---|---|---|
DT ID | DTD0338 Transporter Info | ||||
Gene Name | SLC39A10 | ||||
Transporter Name | Zinc transporter ZIP10 | ||||
Gene ID | |||||
UniProt ID | |||||
Exogenous factors (drugs, dietary constituents, etc.) Modulation of This DT (EGM) | |||||
---|---|---|---|---|---|
Chemical Compound |
|||||
DT Modulation1 |
Zinc Acetate co-treated with motexafin gadolinium affects the expression of SLC39A10 mRNA | [1] | |||
Regulation Mechanism |
Transcription Factor Info | ||||
DT Modulation1 |
Valproic Acid affects the expression of SLC39A10 mRNA | [8] | |||
Regulation Mechanism |
Transcription Factor Info | ||||
DT Modulation2 |
Valproic Acid results in decreased methylation of SLC39A10 gene | [56] | |||
Regulation Mechanism |
Transcription Factor Info | ||||
DT Modulation1 |
Estradiol co-treated with TGFB1 protein results in increased expression of SLC39A10 mRNA | [49] | |||
Regulation Mechanism |
Transcription Factor Info | ||||
DT Modulation1 |
NOG protein co-treated with Phenylmercuric Acetate co-treated with dorsomorphin co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide results in decreased expression of SLC39A10 mRNA | [34] | |||
Regulation Mechanism |
Transcription Factor Info | ||||
DT Modulation1 |
Benzo(a)pyrene affects the methylation of SLC39A10 promoter | [40] | |||
Regulation Mechanism |
Transcription Factor Info | ||||
4-(4-((5-(4,5-dimethyl-2-nitrophenyl)-2-furanyl)methylene)-4,5-dihydro-3-methyl-5-oxo-1H-pyrazol-1-yl)benzoic acid |
1 DT Activity Modulations Related to This Exogenous Factor | Click to Show/Hide the Full List | |||
DT Modulation1 |
4-(4-((5-(4,5-dimethyl-2-nitrophenyl)-2-furanyl)methylene)-4,5-dihydro-3-methyl-5-oxo-1H-pyrazol-1-yl)benzoic acid results in decreased expression of SLC39A10 mRNA | [33] | |||
Regulation Mechanism |
Transcription Factor Info | ||||
4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide |
2 DT Activity Modulations Related to This Exogenous Factor | Click to Show/Hide the Full List | |||
DT Modulation1 |
NOG protein co-treated with p-Chloromercuribenzoic Acid co-treated with dorsomorphin co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide results in decreased expression of SLC39A10 mRNA | [34] | |||
Regulation Mechanism |
Transcription Factor Info | ||||
DT Modulation2 |
NOG protein co-treated with Phenylmercuric Acetate co-treated with dorsomorphin co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide results in decreased expression of SLC39A10 mRNA | [34] | |||
Regulation Mechanism |
Transcription Factor Info | ||||
4-chloro-N-((4-(1,1-dimethylethyl)phenyl)methyl)-3-ethyl-1-methyl-1H-pyrazole-5-carboxamide |
1 DT Activity Modulations Related to This Exogenous Factor | Click to Show/Hide the Full List | |||
DT Modulation1 |
4-chloro-N-((4-(1,1-dimethylethyl)phenyl)methyl)-3-ethyl-1-methyl-1H-pyrazole-5-carboxamide results in decreased expression of SLC39A10 mRNA | [35] | |||
Regulation Mechanism |
Transcription Factor Info | ||||
abrine |
1 DT Activity Modulations Related to This Exogenous Factor | Click to Show/Hide the Full List | |||
DT Modulation1 |
abrine results in decreased expression of SLC39A10 mRNA | [36] | |||
Regulation Mechanism |
Transcription Factor Info | ||||
Acrolein |
2 DT Activity Modulations Related to This Exogenous Factor | Click to Show/Hide the Full List | |||
DT Modulation1 |
Acrolein co-treated with methacrylaldehyde co-treated with alpha-pinene co-treated with Ozone results in increased oxidation of SLC39A10 mRNA | [37] | |||
Regulation Mechanism |
Transcription Factor Info | ||||
DT Modulation2 |
Air Pollutants results in increased abundance of Acrolein co-treated with methacrylaldehyde co-treated with alpha-pinene co-treated with Ozone which results in increased oxidation of SLC39A10 mRNA | [37] | |||
Regulation Mechanism |
Transcription Factor Info | ||||
afuresertib |
1 DT Activity Modulations Related to This Exogenous Factor | Click to Show/Hide the Full List | |||
DT Modulation1 |
afuresertib results in decreased expression of SLC39A10 mRNA | [38] | |||
Regulation Mechanism |
Transcription Factor Info | ||||
alpha-pinene |
2 DT Activity Modulations Related to This Exogenous Factor | Click to Show/Hide the Full List | |||
DT Modulation1 |
Acrolein co-treated with methacrylaldehyde co-treated with alpha-pinene co-treated with Ozone results in increased oxidation of SLC39A10 mRNA | [37] | |||
Regulation Mechanism |
Transcription Factor Info | ||||
DT Modulation2 |
Air Pollutants results in increased abundance of Acrolein co-treated with methacrylaldehyde co-treated with alpha-pinene co-treated with Ozone which results in increased oxidation of SLC39A10 mRNA | [37] | |||
Regulation Mechanism |
Transcription Factor Info | ||||
beta-methylcholine |
1 DT Activity Modulations Related to This Exogenous Factor | Click to Show/Hide the Full List | |||
DT Modulation1 |
beta-methylcholine affects the expression of SLC39A10 mRNA | [41] | |||
Regulation Mechanism |
Transcription Factor Info | ||||
bisphenol A |
2 DT Activity Modulations Related to This Exogenous Factor | Click to Show/Hide the Full List | |||
DT Modulation1 |
bisphenol A results in decreased expression of SLC39A10 mRNA | [29] | |||
Regulation Mechanism |
Transcription Factor Info | ||||
DT Modulation2 |
bisphenol A results in decreased expression of SLC39A10 protein | [42] | |||
Regulation Mechanism |
Transcription Factor Info | ||||
Cadmium Chloride |
2 DT Activity Modulations Related to This Exogenous Factor | Click to Show/Hide the Full List | |||
DT Modulation1 |
Cadmium Chloride results in decreased expression of SLC39A10 mRNA | [44] | |||
Regulation Mechanism |
Transcription Factor Info | ||||
DT Modulation2 |
Cadmium Chloride results in increased abundance of Cadmium which results in decreased expression of SLC39A10 mRNA | [43] | |||
Regulation Mechanism |
Transcription Factor Info | ||||
CGP 52608 |
1 DT Activity Modulations Related to This Exogenous Factor | Click to Show/Hide the Full List | |||
DT Modulation1 |
CGP 52608 promotes the reaction RORA protein binds to SLC39A10 gene | [45] | |||
Regulation Mechanism |
Transcription Factor Info | ||||
coumarin |
1 DT Activity Modulations Related to This Exogenous Factor | Click to Show/Hide the Full List | |||
DT Modulation1 |
coumarin results in increased phosphorylation of SLC39A10 protein | [46] | |||
Regulation Mechanism |
Transcription Factor Info | ||||
dicrotophos |
1 DT Activity Modulations Related to This Exogenous Factor | Click to Show/Hide the Full List | |||
DT Modulation1 |
dicrotophos results in decreased expression of SLC39A10 mRNA | [28] | |||
Regulation Mechanism |
Transcription Factor Info | ||||
di-n-butylphosphoric acid |
1 DT Activity Modulations Related to This Exogenous Factor | Click to Show/Hide the Full List | |||
DT Modulation1 |
di-n-butylphosphoric acid affects the expression of SLC39A10 mRNA | [47] | |||
Regulation Mechanism |
Transcription Factor Info | ||||
dorsomorphin |
2 DT Activity Modulations Related to This Exogenous Factor | Click to Show/Hide the Full List | |||
DT Modulation1 |
NOG protein co-treated with p-Chloromercuribenzoic Acid co-treated with dorsomorphin co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide results in decreased expression of SLC39A10 mRNA | [34] | |||
Regulation Mechanism |
Transcription Factor Info | ||||
DT Modulation2 |
NOG protein co-treated with Phenylmercuric Acetate co-treated with dorsomorphin co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide results in decreased expression of SLC39A10 mRNA | [34] | |||
Regulation Mechanism |
Transcription Factor Info | ||||
epigallocatechin gallate |
1 DT Activity Modulations Related to This Exogenous Factor | Click to Show/Hide the Full List | |||
DT Modulation1 |
potassium chromate(VI) co-treated with epigallocatechin gallate results in decreased expression of SLC39A10 mRNA | [48] | |||
Regulation Mechanism |
Transcription Factor Info | ||||
FR900359 |
1 DT Activity Modulations Related to This Exogenous Factor | Click to Show/Hide the Full List | |||
DT Modulation1 |
FR900359 affects the phosphorylation of SLC39A10 protein | [50] | |||
Regulation Mechanism |
Transcription Factor Info | ||||
gadodiamide |
1 DT Activity Modulations Related to This Exogenous Factor | Click to Show/Hide the Full List | |||
DT Modulation1 |
gadodiamide results in increased expression of SLC39A10 mRNA | [4] | |||
Regulation Mechanism |
Transcription Factor Info | ||||
methacrylaldehyde |
2 DT Activity Modulations Related to This Exogenous Factor | Click to Show/Hide the Full List | |||
DT Modulation1 |
Acrolein co-treated with methacrylaldehyde co-treated with alpha-pinene co-treated with Ozone results in increased oxidation of SLC39A10 mRNA | [37] | |||
Regulation Mechanism |
Transcription Factor Info | ||||
DT Modulation2 |
Air Pollutants results in increased abundance of Acrolein co-treated with methacrylaldehyde co-treated with alpha-pinene co-treated with Ozone which results in increased oxidation of SLC39A10 mRNA | [37] | |||
Regulation Mechanism |
Transcription Factor Info | ||||
Methyl Methanesulfonate |
1 DT Activity Modulations Related to This Exogenous Factor | Click to Show/Hide the Full List | |||
DT Modulation1 |
Methyl Methanesulfonate results in decreased expression of SLC39A10 mRNA | [21] | |||
Regulation Mechanism |
Transcription Factor Info | ||||
motexafin gadolinium |
2 DT Activity Modulations Related to This Exogenous Factor | Click to Show/Hide the Full List | |||
DT Modulation1 |
motexafin gadolinium affects the expression of SLC39A10 mRNA | [1] | |||
Regulation Mechanism |
Transcription Factor Info | ||||
DT Modulation2 |
Zinc Acetate co-treated with motexafin gadolinium affects the expression of SLC39A10 mRNA | [1] | |||
Regulation Mechanism |
Transcription Factor Info | ||||
N,N,N',N'-tetrakis(2-pyridylmethyl)ethylenediamine |
3 DT Activity Modulations Related to This Exogenous Factor | Click to Show/Hide the Full List | |||
DT Modulation1 |
ochratoxin A co-treated with N,N,N',N'-tetrakis(2-pyridylmethyl)ethylenediamine co-treated with Zinc results in decreased expression of SLC39A10 mRNA | [51] | |||
Regulation Mechanism |
Transcription Factor Info | ||||
DT Modulation2 |
ochratoxin A co-treated with N,N,N',N'-tetrakis(2-pyridylmethyl)ethylenediamine results in decreased expression of SLC39A10 mRNA | [51] | |||
Regulation Mechanism |
Transcription Factor Info | ||||
DT Modulation3 |
Zinc co-treated with N,N,N',N'-tetrakis(2-pyridylmethyl)ethylenediamine results in decreased expression of SLC39A10 mRNA | [51] | |||
Regulation Mechanism |
Transcription Factor Info | ||||
NSC 689534 |
1 DT Activity Modulations Related to This Exogenous Factor | Click to Show/Hide the Full List | |||
DT Modulation1 |
NSC 689534 results in increased expression of SLC39A10 mRNA | [20] | |||
Regulation Mechanism |
Transcription Factor Info | ||||
Ozone |
4 DT Activity Modulations Related to This Exogenous Factor | Click to Show/Hide the Full List | |||
DT Modulation1 |
Acrolein co-treated with methacrylaldehyde co-treated with alpha-pinene co-treated with Ozone results in increased oxidation of SLC39A10 mRNA | [37] | |||
Regulation Mechanism |
Transcription Factor Info | ||||
DT Modulation2 |
Air Pollutants results in increased abundance of Acrolein co-treated with methacrylaldehyde co-treated with alpha-pinene co-treated with Ozone which results in increased oxidation of SLC39A10 mRNA | [37] | |||
Regulation Mechanism |
Transcription Factor Info | ||||
DT Modulation3 |
Air Pollutants results in increased abundance of Ozone which affects the expression of SLC39A10 mRNA | [52] | |||
Regulation Mechanism |
Transcription Factor Info | ||||
DT Modulation4 |
Volatile Organic Compounds co-treated with Ozone results in increased oxidation of SLC39A10 mRNA | [37] | |||
Regulation Mechanism |
Transcription Factor Info | ||||
p-Chloromercuribenzoic Acid |
2 DT Activity Modulations Related to This Exogenous Factor | Click to Show/Hide the Full List | |||
DT Modulation1 |
NOG protein co-treated with p-Chloromercuribenzoic Acid co-treated with dorsomorphin co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide results in decreased expression of SLC39A10 mRNA | [34] | |||
Regulation Mechanism |
Transcription Factor Info | ||||
DT Modulation2 |
p-Chloromercuribenzoic Acid results in decreased expression of SLC39A10 mRNA | [24] | |||
Regulation Mechanism |
Transcription Factor Info | ||||
PCI 5002 |
1 DT Activity Modulations Related to This Exogenous Factor | Click to Show/Hide the Full List | |||
DT Modulation1 |
PCI 5002 co-treated with Zinc results in increased expression of SLC39A10 mRNA | [53] | |||
Regulation Mechanism |
Transcription Factor Info | ||||
perfluorooctane sulfonic acid |
1 DT Activity Modulations Related to This Exogenous Factor | Click to Show/Hide the Full List | |||
DT Modulation1 |
perfluorooctane sulfonic acid results in decreased expression of SLC39A10 mRNA | [26] | |||
Regulation Mechanism |
Transcription Factor Info | ||||
potassium chromate(VI) |
2 DT Activity Modulations Related to This Exogenous Factor | Click to Show/Hide the Full List | |||
DT Modulation1 |
potassium chromate(VI) co-treated with epigallocatechin gallate results in decreased expression of SLC39A10 mRNA | [48] | |||
Regulation Mechanism |
Transcription Factor Info | ||||
DT Modulation2 |
potassium chromate(VI) results in decreased expression of SLC39A10 mRNA | [48] | |||
Regulation Mechanism |
Transcription Factor Info | ||||
Rotenone |
1 DT Activity Modulations Related to This Exogenous Factor | Click to Show/Hide the Full List | |||
DT Modulation1 |
Rotenone results in increased expression of SLC39A10 protein | [54] | |||
Regulation Mechanism |
Transcription Factor Info | ||||
Silicon Dioxide |
1 DT Activity Modulations Related to This Exogenous Factor | Click to Show/Hide the Full List | |||
DT Modulation1 |
Silicon Dioxide analog results in increased expression of SLC39A10 mRNA | [55] | |||
Regulation Mechanism |
Transcription Factor Info | ||||
Silver |
1 DT Activity Modulations Related to This Exogenous Factor | Click to Show/Hide the Full List | |||
DT Modulation1 |
Silver results in decreased expression of SLC39A10 mRNA | [22] | |||
Regulation Mechanism |
Transcription Factor Info | ||||
sodium arsenite |
2 DT Activity Modulations Related to This Exogenous Factor | Click to Show/Hide the Full List | |||
DT Modulation1 |
sodium arsenite results in decreased expression of SLC39A10 mRNA | [44] | |||
Regulation Mechanism |
Transcription Factor Info | ||||
DT Modulation2 |
sodium arsenite results in increased abundance of Arsenic which results in decreased expression of SLC39A10 mRNA | [39] | |||
Regulation Mechanism |
Transcription Factor Info | ||||
Tetrachlorodibenzodioxin |
1 DT Activity Modulations Related to This Exogenous Factor | Click to Show/Hide the Full List | |||
DT Modulation1 |
Tetrachlorodibenzodioxin results in increased expression of SLC39A10 mRNA | [18] | |||
Regulation Mechanism |
Transcription Factor Info | ||||
triphenyl phosphate |
1 DT Activity Modulations Related to This Exogenous Factor | Click to Show/Hide the Full List | |||
DT Modulation1 |
triphenyl phosphate affects the expression of SLC39A10 mRNA | [47] | |||
Regulation Mechanism |
Transcription Factor Info | ||||
Zinc |
4 DT Activity Modulations Related to This Exogenous Factor | Click to Show/Hide the Full List | |||
DT Modulation1 |
ochratoxin A co-treated with N,N,N',N'-tetrakis(2-pyridylmethyl)ethylenediamine co-treated with Zinc results in decreased expression of SLC39A10 mRNA | [51] | |||
Regulation Mechanism |
Transcription Factor Info | ||||
DT Modulation2 |
PCI 5002 co-treated with Zinc results in increased expression of SLC39A10 mRNA | [53] | |||
Regulation Mechanism |
Transcription Factor Info | ||||
DT Modulation3 |
SLC39A10 protein results in increased transport of Zinc | [57] | |||
Regulation Mechanism |
Transcription Factor Info | ||||
DT Modulation4 |
Zinc co-treated with N,N,N',N'-tetrakis(2-pyridylmethyl)ethylenediamine results in decreased expression of SLC39A10 mRNA | [51] | |||
Regulation Mechanism |
Transcription Factor Info | ||||
Approved Drug |
|||||
Zinc Acetate |
2 DT Activity Modulations Related to This Exogenous Factor | Click to Show/Hide the Full List | |||
DT Modulation1 |
Zinc Acetate affects the expression of SLC39A10 | [1] | |||
Hydrogen Peroxide |
1 DT Activity Modulations Related to This Exogenous Factor | Click to Show/Hide the Full List | |||
DT Modulation1 |
Hydrogen Peroxide affects the expression of SLC39A10 | [2] | |||
Calcitriol |
1 DT Activity Modulations Related to This Exogenous Factor | Click to Show/Hide the Full List | |||
DT Modulation1 |
Calcitriol inhibits the expression of SLC39A10 | [3] | |||
Gadodiamide |
1 DT Activity Modulations Related to This Exogenous Factor | Click to Show/Hide the Full List | |||
DT Modulation1 |
Gadodiamide increases the expression of SLC39A10 | [4] | |||
Valproic Acid |
3 DT Activity Modulations Related to This Exogenous Factor | Click to Show/Hide the Full List | |||
DT Modulation1 |
Valproic Acid inhibits the expression of SLC39A10 | [5] | |||
Zidovudine |
1 DT Activity Modulations Related to This Exogenous Factor | Click to Show/Hide the Full List | |||
DT Modulation1 |
Zidovudine inhibits the expression of SLC39A10 | [6] | |||
Zoledronic Acid |
1 DT Activity Modulations Related to This Exogenous Factor | Click to Show/Hide the Full List | |||
DT Modulation1 |
Zoledronic Acid inhibits the expression of SLC39A10 | [7] | |||
Carbamazepine |
1 DT Activity Modulations Related to This Exogenous Factor | Click to Show/Hide the Full List | |||
DT Modulation1 |
Carbamazepine affects the expression of SLC39A10 | [8] | |||
Cisplatin |
1 DT Activity Modulations Related to This Exogenous Factor | Click to Show/Hide the Full List | |||
DT Modulation1 |
Cisplatin inhibits the expression of SLC39A10 | [9] | |||
Arsenic Trioxide |
1 DT Activity Modulations Related to This Exogenous Factor | Click to Show/Hide the Full List | |||
DT Modulation1 |
Arsenic Trioxide inhibits the expression of SLC39A10 | [10] | |||
Acetaminophen |
1 DT Activity Modulations Related to This Exogenous Factor | Click to Show/Hide the Full List | |||
DT Modulation1 |
Acetaminophen increases the expression of SLC39A10 | [11] | |||
Doxorubicin |
1 DT Activity Modulations Related to This Exogenous Factor | Click to Show/Hide the Full List | |||
DT Modulation1 |
Doxorubicin increases the expression of SLC39A10 | [12] | |||
Temozolomide |
1 DT Activity Modulations Related to This Exogenous Factor | Click to Show/Hide the Full List | |||
DT Modulation1 |
Temozolomide inhibits the expression of SLC39A10 | [13] | |||
Ivermectin |
1 DT Activity Modulations Related to This Exogenous Factor | Click to Show/Hide the Full List | |||
DT Modulation1 |
Ivermectin inhibits the expression of SLC39A10 | [14] | |||
Tretinoin |
1 DT Activity Modulations Related to This Exogenous Factor | Click to Show/Hide the Full List | |||
DT Modulation1 |
Tretinoin inhibits the expression of SLC39A10 | [15] | |||
Estradiol |
2 DT Activity Modulations Related to This Exogenous Factor | Click to Show/Hide the Full List | |||
DT Modulation1 |
Estradiol inhibits the expression of SLC39A10 | [16] | |||
Cyclosporine |
1 DT Activity Modulations Related to This Exogenous Factor | Click to Show/Hide the Full List | |||
DT Modulation1 |
Cyclosporine inhibits the expression of SLC39A10 | [17] | |||
Drug in Phase 2 Trial |
|||||
Motexafin gadolinium |
1 DT Activity Modulations Related to This Exogenous Factor | Click to Show/Hide the Full List | |||
DT Modulation1 |
Motexafin gadolinium affects the expression of SLC39A10 | [1] | |||
Bisphenol A |
1 DT Activity Modulations Related to This Exogenous Factor | Click to Show/Hide the Full List | |||
DT Modulation1 |
Bisphenol A inhibits the expression of SLC39A10 | [29] | |||
Drug in Phase 1 Trial |
|||||
Quercetin |
1 DT Activity Modulations Related to This Exogenous Factor | Click to Show/Hide the Full List | |||
DT Modulation1 |
Quercetin increases the expression of SLC39A10 | [16] | |||
Dihydrotestosterone |
1 DT Activity Modulations Related to This Exogenous Factor | Click to Show/Hide the Full List | |||
DT Modulation1 |
Dihydrotestosterone increases the expression of SLC39A10 | [30] | |||
Investigative Drug |
|||||
Phenylmercuric Acetate |
2 DT Activity Modulations Related to This Exogenous Factor | Click to Show/Hide the Full List | |||
DT Modulation1 |
Phenylmercuric Acetate inhibits the expression of SLC39A10 | [24] | |||
Patented Pharmaceutical Agent |
|||||
NSC-689534 |
1 DT Activity Modulations Related to This Exogenous Factor | Click to Show/Hide the Full List | |||
DT Modulation1 |
NSC-689534 increases the expression of SLC39A10 | [20] | |||
Natural Product |
|||||
Tobacco Smoke Pollution |
1 DT Activity Modulations Related to This Exogenous Factor | Click to Show/Hide the Full List | |||
DT Modulation1 |
Tobacco Smoke Pollution inhibits the expression of SLC39A10 | [31] | |||
Traditional Medicine |
|||||
Jinfukang |
1 DT Activity Modulations Related to This Exogenous Factor | Click to Show/Hide the Full List | |||
DT Modulation1 |
Jinfukang inhibits the expression of SLC39A10 | [27] | |||
Plant Extract |
|||||
Grape Seed Proanthocyanidins |
1 DT Activity Modulations Related to This Exogenous Factor | Click to Show/Hide the Full List | |||
DT Modulation1 |
Grape Seed Proanthocyanidins increases the expression of SLC39A10 | [19] | |||
Environmental toxicant |
|||||
Polychlorinated dibenzodioxin |
1 DT Activity Modulations Related to This Exogenous Factor | Click to Show/Hide the Full List | |||
DT Modulation1 |
Polychlorinated dibenzodioxin increases the expression of SLC39A10 | [18] | |||
Mycotoxins |
|||||
Aflatoxin B1 |
2 DT Activity Modulations Related to This Exogenous Factor | Click to Show/Hide the Full List | |||
DT Modulation1 |
Aflatoxin B1 increases the expression of SLC39A10 | [25] | |||
DT Modulation2 |
Aflatoxin B1 affects the expression of SLC39A10 protein | [18] | |||
Regulation Mechanism |
Transcription Factor Info | ||||
ochratoxin A |
2 DT Activity Modulations Related to This Exogenous Factor | Click to Show/Hide the Full List | |||
DT Modulation1 |
ochratoxin A co-treated with N,N,N',N'-tetrakis(2-pyridylmethyl)ethylenediamine co-treated with Zinc results in decreased expression of SLC39A10 mRNA | [51] | |||
Regulation Mechanism |
Transcription Factor Info | ||||
DT Modulation2 |
ochratoxin A co-treated with N,N,N',N'-tetrakis(2-pyridylmethyl)ethylenediamine results in decreased expression of SLC39A10 mRNA | [51] | |||
Regulation Mechanism |
Transcription Factor Info | ||||
Carcinogen |
|||||
Ethyl Methanesulfonate |
1 DT Activity Modulations Related to This Exogenous Factor | Click to Show/Hide the Full List | |||
DT Modulation1 |
Ethyl Methanesulfonate inhibits the expression of SLC39A10 | [21] | |||
Benzo(a)pyrene |
2 DT Activity Modulations Related to This Exogenous Factor | Click to Show/Hide the Full List | |||
DT Modulation1 |
Benzo(a)pyrene increases the expression of SLC39A10 | [32] | |||
Arsenic |
1 DT Activity Modulations Related to This Exogenous Factor | Click to Show/Hide the Full List | |||
DT Modulation1 |
sodium arsenite results in increased abundance of Arsenic which results in decreased expression of SLC39A10 mRNA | [39] | |||
Regulation Mechanism |
Transcription Factor Info | ||||
Cadmium |
1 DT Activity Modulations Related to This Exogenous Factor | Click to Show/Hide the Full List | |||
DT Modulation1 |
Cadmium Chloride results in increased abundance of Cadmium which results in decreased expression of SLC39A10 mRNA | [43] | |||
Regulation Mechanism |
Transcription Factor Info | ||||
Pesticide/Insecticide |
|||||
Dicrotophos |
1 DT Activity Modulations Related to This Exogenous Factor | Click to Show/Hide the Full List | |||
DT Modulation1 |
Dicrotophos inhibits the expression of SLC39A10 | [28] | |||
Health and Environmental Toxicant |
|||||
tris(1,3-dichloro-2-propyl)phosphate |
1 DT Activity Modulations Related to This Exogenous Factor | Click to Show/Hide the Full List | |||
DT Modulation1 |
tris(1,3-dichloro-2-propyl)phosphate inhibits the expression of SLC39A10 | [23] | |||
Perfluorooctane sulfonic acid |
1 DT Activity Modulations Related to This Exogenous Factor | Click to Show/Hide the Full List | |||
DT Modulation1 |
Perfluorooctane sulfonic acid inhibits the expression of SLC39A10 | [26] | |||
Nanoparticle |
|||||
Silver nanoparticle |
1 DT Activity Modulations Related to This Exogenous Factor | Click to Show/Hide the Full List | |||
DT Modulation1 |
Silver nanoparticle inhibits the expression of SLC39A10 | [22] | |||
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