Detail Information of Genetic Polymorphisms
| General Information of Drug Transporter (DT) | |||||
|---|---|---|---|---|---|
| DT ID | DTD0338 Transporter Info | ||||
| Gene Name | SLC39A10 | ||||
| Protein Name | Zinc transporter ZIP10 | ||||
| Gene ID | |||||
| UniProt ID | |||||
| Genetic Polymorphisms of DT (GPD) | |||||
| Genetic Polymorphism | rs149319538 | ||||
| Site of GPD | chr2:195415239 (GRCh38.p12) | ||||
| GPD Type | SNP | ||||
| Allele(s) in dbSNP | T>C | ||||
| Minor Allele Frequency | T=0.9920/1963 (Global) | ||||
| Allele C | Click to Show/Hide the Full List of Affected Drugs: 1 Drugs in Total | ||||
| Buprenorphine | N.A. | Fractures, Bone | Allele C is associated with increased clinical benefit to buprenorphine in people with Opioid-Related Disorders as compared to allele T. | [ 1] | |
| References | |||||
| 1 | Multi-ancestry genome-wide association meta-analysis of buprenorphine treatment response. Neuropsychopharmacology. 2025 May 06. | ||||
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