Drug Transporter (DT) Information

General Information of DT
DT ID DTD0350
Gene Name SLC39A9
Protein Name Zinc transporter ZIP9
Gene ID
55334
UniProt ID
Q9NUM3
TCDB ID
2.A.5.6.1
3D Structure

Modelled DT Structure

Method: multi-sequence alignment based machine learning

Detail: Structure Info

Synonyms SLC39A9; Solute carrier family 39 member 9; ZIP-9; ZIP9; Zinc transporter ZIP9
DT Family Zinc (Zn(2+))-Iron (Fe(2+)) Permease (ZIP) Family ;
Function This transporter may act as a zinc-influx transporter.
Endogenous Substrate(s) Zn2+
Variability Data of This Drug Transporter (DT)

Regulatory Variability Data of This DT (VARIDT 4.0)

(α) Tissue Distribution Level of Zinc transporter ZIP9
Tissue Distribution Level (TD)

(β) Cell Distribution Level of Zinc transporter ZIP9
Cell Distribution Level (CD)

(γ) Organelle Distribution Level of Zinc transporter ZIP9
Organelle Distribution Level (Subc)

Regulatory Variability Data of This DT

(α) Microbiota Influence of Zinc transporter ZIP9
Microbiota Influence (MBI)

(β) Post-translational Modification of Zinc transporter ZIP9
Post-translational Modification (PTM)

(γ) Transcriptional Regulation of Zinc transporter ZIP9
Transcriptional Regulation (TSR)

(δ) Epigenetic Regulation of Zinc transporter ZIP9
Epigenetic Regulation (EGR)

(ε) Exogenous Modulation of Zinc transporter ZIP9
Exogenous Modulation (EGM)

General Variability Data of This DT

(α) Genetic Polymorphisms of Zinc transporter ZIP9
Genetic Polymorphisms of This DT (GPD)

(β) Disease-specific Protein Abundances of Zinc transporter ZIP9
Disease-specific Protein Abundances of This DT (DPAD)

(γ) Species- and Tissue-specific DT Abundances
Species/Tissue-specific Protein Abundances of This DT (S/TPAD)
Molecular Transporting Profile of This DT

Full List of Drug(s) Transported by This DT

 Withdrawn, Discontinued or Preclinical Drug

 Click to Show/Hide the Full List of Drug:           1 Drugs in Total
Drug Name Highest Status Detail Indication ICD 11 Ref
Zinc salts
 Preclinical Drug Info Arthritis FA5Z [1]
References
1 A ZIP6-ZIP10 heteromer controls NCAM1 phosphorylation and integration into focal adhesion complexes during epithelial-to-mesenchymal transition. Sci Rep. 2017 Jan 18;7:40313.

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