Microbe Species Information | VARIDT

General Information of This Microbe species
Species ID	MIC00071
Species Name	Shigella flexneri
Taxonomy ID	623
Lineage	Kingdom:Bacteria Phylum:Pseudomonadota Class:Gammaproteobacteria Order:Enterobacterales Family:Enterobacteriaceae Genus: Shigella Species: Shigella flexneri

Drug Transporter(s) Regulated by This Microbe species
Class1: Microbiota direct bioaccumulation of drugs
CACNA1A	Transporter Info	Health [ICD11: N.A]			[1], [2], [3]
IREG1	Transporter Info	Health [ICD11: N.A]			[1], [2], [3]
NRAMP2	Transporter Info	Health [ICD11: N.A]			[1], [2], [3]
SLC11A1	Transporter Info	Health [ICD11: N.A]			[4], [5], [6], [7]
SLC25A28	Transporter Info	Health [ICD11: N.A]			[1], [2], [3]
SLC25A37	Transporter Info	Health [ICD11: N.A]			[1], [2], [3]
ZIP14	Transporter Info	Health [ICD11: N.A]			[1], [2], [3]
ZIP8	Transporter Info	Health [ICD11: N.A]			[1], [2], [3]

Species Relative Abundances of This Microbe species

References
1	Sequestration and scavenging of iron in infection. Infect Immun. 2013 Oct;81(10):3503-14.
2	Ferric dicitrate transport system (Fec) of Shigella flexneri 2a YSH6000 is encoded on a novel pathogenicity island carrying multiple antibiotic resistance genes. Infect Immun. 2001 Oct;69(10):6012-21.
3	Iron and manganese transport in mammalian systems. Biochim Biophys Acta Mol Cell Res. 2021 Jan;1868(1):118890.
4	Manganese homeostasis and utilization in pathogenic bacteria. Mol Microbiol. 2015 Jul;97(2):216-28.
5	Role and regulation of the Shigella flexneri sit and MntH systems. Infect Immun. 2006 Aug;74(8):4666-72.
6	Human iron transporters. Genes Nutr. 2011 Feb;6(1):45-54.
7	Iron transport machinery of human cells: players and their interactions. Curr Top Membr. 2012;69:67-93.

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