Search for Drug Transporter(s)
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| DTD0001 Transporter Info |
Transporter Name | Multidrug resistance-associated protein 1 (ABCC1) | ||||
|---|---|---|---|---|---|---|
| Family | ATP-Binding Cassette (ABC) Superfamily | |||||
| Phenotypic/Regulatory Variability | ||||||
| Representative Substrate(s) | Antimony; Arsenic triglutathione | |||||
| Distribution Variability | ||||||
| Structural Variability | ||||||
| Representative Drug | Methotrexate Drug Info | |||||
MBI Info 
PTM Info 
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EGR Info 
EGM Info 
TD Info 
CD Info 
OD Info 
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ISD Info 
OIC Info 
XSV Info | DTD0002 Transporter Info |
Transporter Name | Multidrug resistance-associated protein 2 (ABCC2) | ||||
|---|---|---|---|---|---|---|
| Family | ATP-Binding Cassette (ABC) Superfamily | |||||
| Phenotypic/Regulatory Variability | ||||||
| Representative Substrate(s) | Alkaloids; Glutahione conjugates | |||||
| Distribution Variability | ||||||
| Structural Variability | ||||||
| Representative Drug | Methotrexate Drug Info | |||||
| DTD0003 Transporter Info |
Transporter Name | P-glycoprotein 1 (ABCB1) | ||||
|---|---|---|---|---|---|---|
| Family | ATP-Binding Cassette (ABC) Superfamily | |||||
| Phenotypic/Regulatory Variability | ||||||
| Representative Substrate(s) | Long-chain fatty acids; Organic cations | |||||
| Distribution Variability | ||||||
| Structural Variability | ||||||
| Representative Drug | Digoxin Drug Info | |||||
| DTD0004 Transporter Info |
Transporter Name | Breast cancer resistance protein (ABCG2) | ||||
|---|---|---|---|---|---|---|
| Family | ATP-Binding Cassette (ABC) Superfamily | |||||
| Phenotypic/Regulatory Variability | ||||||
| Representative Substrate(s) | Bisbenzimide; Pheophorbide A | |||||
| Distribution Variability | ||||||
| Structural Variability | ||||||
| Representative Drug | Methotrexate Drug Info | |||||
| DTD0008 Transporter Info |
Transporter Name | Organic anion transporting polypeptide 1B1 (SLCO1B1) | ||||
|---|---|---|---|---|---|---|
| Family | Organo Anion Transporter (OAT) Family | |||||
| Phenotypic/Regulatory Variability | ||||||
| Representative Substrate(s) | Bisglucuronosyl bilirubin; Cholate | |||||
| Distribution Variability | ||||||
| Structural Variability | ||||||
| Representative Drug | Methotrexate Drug Info | |||||
| DTD0012 Transporter Info |
Transporter Name | Multidrug resistance-associated protein 3 (ABCC3) | ||||
|---|---|---|---|---|---|---|
| Family | ATP-Binding Cassette (ABC) Superfamily | |||||
| Phenotypic/Regulatory Variability | ||||||
| Representative Substrate(s) | Canicular organoanions; GSH-X | |||||
| Distribution Variability | ||||||
| Structural Variability | ||||||
| Representative Drug | Methotrexate Drug Info | |||||
| DTD0015 Transporter Info |
Transporter Name | Multidrug resistance-associated protein 4 (ABCC4) | ||||
|---|---|---|---|---|---|---|
| Family | ATP-Binding Cassette (ABC) Superfamily | |||||
| Phenotypic/Regulatory Variability | ||||||
| Representative Substrate(s) | Cyclic nucleotides; Nucleotide analogues | |||||
| Distribution Variability | ||||||
| Structural Variability | ||||||
| Representative Drug | Methotrexate Drug Info | |||||
| DTD0030 Transporter Info |
Transporter Name | Organic anion transporting polypeptide 1B3 (SLCO1B3) | ||||
|---|---|---|---|---|---|---|
| Family | Organo Anion Transporter (OAT) Family | |||||
| Phenotypic/Regulatory Variability | ||||||
| Representative Substrate(s) | Cholate; Cholecystokinin | |||||
| Distribution Variability | ||||||
| Structural Variability | ||||||
| Representative Drug | Methotrexate Drug Info | |||||
| DTD0031 Transporter Info |
Transporter Name | Organic anion transporting polypeptide 2B1 (SLCO2B1) | ||||
|---|---|---|---|---|---|---|
| Family | Organo Anion Transporter (OAT) Family | |||||
| Phenotypic/Regulatory Variability | ||||||
| Representative Substrate(s) | Organoanions | |||||
| Distribution Variability | ||||||
| Structural Variability | ||||||
| Representative Drug | Dinoprostone Drug Info | |||||
| DTD0055 Transporter Info |
Transporter Name | TAP-like protein (ABCB9) | ||||
|---|---|---|---|---|---|---|
| Family | ATP-Binding Cassette (ABC) Superfamily | |||||
| Phenotypic/Regulatory Variability | ||||||
| Representative Substrate(s) | Peptides | |||||
| Distribution Variability | ||||||
| Structural Variability | ||||||
| Representative Drug | Paclitaxel Drug Info | |||||
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