Detail Information of Transcriptional Regulations

General Information of Drug Transporter (DT)
DT ID	DTD0481 Transporter Info
Gene Name	SLC9A1
Transporter Name	Sodium/hydrogen exchanger 1
Gene ID	6548
UniProt ID	P19634

Transcriptional Regulation of This DT (TSR)

TF Superclass1: Basic domains
Class1.1: Basic leucine zipper factors		Click to Show/Hide the Full List of 9 TF(s) Regulating This DT
ATF2		Click to Show/Hide to Show 1 Transcriptional Phenomena
Transcriptional Phenomenon1	Direct binding to SLC9A1 gene			[1]
TF Protein Name	Cyclic AMP-dependent transcription factor ATF-2		Transcription Factor Info
Tissue	Blood; Embryo
Related DT Changes	Direct regulating
Experiment method	TF-transporter regulations were collected from ChIP-Seq datasets.
Detailed Description	Cyclic AMP-dependent transcription factor ATF-2 (ATF2) can directly bind to the SLC9A1 gene, which in turn affects the expression or function of the drug transporter Sodium/hydrogen exchanger 1.
ATF3		Click to Show/Hide to Show 2 Transcriptional Phenomena
Transcriptional Phenomenon1	Repression of SLC9A1 gene in glioblastoma multiforme condition			[2]
TF Protein Name	Cyclic AMP-dependent transcription factor ATF-3		Transcription Factor Info
Studied Phenotype	.
Related DT Changes	Down regulating
Detailed Description	Cyclic AMP-dependent transcription factor ATF-3 (ATF3) has been reported to repress the transcription of SLC9A1 gene in glioblastoma multiforme condition, which leads to a decreased expression of the drug transporter Sodium/hydrogen exchanger 1.
Transcriptional Phenomenon2	Direct binding to SLC9A1 gene			[3]
TF Protein Name	Cyclic AMP-dependent transcription factor ATF-3		Transcription Factor Info
Tissue	Colon
Related DT Changes	Direct regulating
Experiment method	TF-transporter regulations were collected from ChIP-Seq datasets.
Detailed Description	Cyclic AMP-dependent transcription factor ATF-3 (ATF3) can directly bind to the SLC9A1 gene, which in turn affects the expression or function of the drug transporter Sodium/hydrogen exchanger 1.
CEBPA		Click to Show/Hide to Show 1 Transcriptional Phenomena
Transcriptional Phenomenon1	Direct binding to SLC9A1 gene			[4]
TF Protein Name	CCAAT/enhancer-binding protein alpha		Transcription Factor Info
Tissue	Embryo
Related DT Changes	Direct regulating
Experiment method	TF-transporter regulations were collected from ChIP-Seq datasets.
Detailed Description	CCAAT/enhancer-binding protein alpha (CEBPA) can directly bind to the SLC9A1 gene, which in turn affects the expression or function of the drug transporter Sodium/hydrogen exchanger 1.
CEBPB		Click to Show/Hide to Show 1 Transcriptional Phenomena
Transcriptional Phenomenon1	Direct binding to SLC9A1 gene			[5]
TF Protein Name	CCAAT/enhancer-binding protein beta		Transcription Factor Info
Tissue	Blood
Related DT Changes	Direct regulating
Experiment method	TF-transporter regulations were collected from ChIP-Seq datasets.
Detailed Description	CCAAT/enhancer-binding protein beta (CEBPB) can directly bind to the SLC9A1 gene, which in turn affects the expression or function of the drug transporter Sodium/hydrogen exchanger 1.
CEBPD		Click to Show/Hide to Show 1 Transcriptional Phenomena
Transcriptional Phenomenon1	Direct binding to SLC9A1 gene			[1]
TF Protein Name	CCAAT/enhancer-binding protein delta		Transcription Factor Info
Tissue	Aorta
Related DT Changes	Direct regulating
Experiment method	TF-transporter regulations were collected from ChIP-Seq datasets.
Detailed Description	CCAAT/enhancer-binding protein delta (CEBPD) can directly bind to the SLC9A1 gene, which in turn affects the expression or function of the drug transporter Sodium/hydrogen exchanger 1.
FOSL1		Click to Show/Hide to Show 1 Transcriptional Phenomena
Transcriptional Phenomenon1	Direct binding to SLC9A1 gene			[4]
TF Protein Name	Fos-related antigen 1		Transcription Factor Info
Tissue	Bone marrow; Breast; Embryo
Related DT Changes	Direct regulating
Experiment method	TF-transporter regulations were collected from ChIP-Seq datasets.
Detailed Description	Fos-related antigen 1 (FOSL1) can directly bind to the SLC9A1 gene, which in turn affects the expression or function of the drug transporter Sodium/hydrogen exchanger 1.
JUN		Click to Show/Hide to Show 1 Transcriptional Phenomena
Transcriptional Phenomenon1	Binding to SLC9A1 gene in coronary artery disease condition			[6]
TF Protein Name	Transcription factor Jun		Transcription Factor Info
Studied Phenotype	.
Related DT Changes	Direct regulating
Detailed Description	Transcription factor Jun (JUN) has been reported to bind to the transcription of SLC9A1 gene in coronary artery disease condition, which leads to an affected expression of the drug transporter Sodium/hydrogen exchanger 1.
JUNB		Click to Show/Hide to Show 1 Transcriptional Phenomena
Transcriptional Phenomenon1	Direct binding to SLC9A1 gene			[5]
TF Protein Name	Transcription factor JunB		Transcription Factor Info
Tissue	Aorta
Related DT Changes	Direct regulating
Experiment method	TF-transporter regulations were collected from ChIP-Seq datasets.
Detailed Description	Transcription factor JunB (JUNB) can directly bind to the SLC9A1 gene, which in turn affects the expression or function of the drug transporter Sodium/hydrogen exchanger 1.
JUND		Click to Show/Hide to Show 2 Transcriptional Phenomena
Transcriptional Phenomenon1	Binding to SLC9A1 gene in coronary artery disease condition			[6]
TF Protein Name	Transcription factor JunD		Transcription Factor Info
Studied Phenotype	.
Related DT Changes	Direct regulating
Detailed Description	Transcription factor JunD (JUND) has been reported to bind to the transcription of SLC9A1 gene in coronary artery disease condition, which leads to an affected expression of the drug transporter Sodium/hydrogen exchanger 1.
Transcriptional Phenomenon2	Direct binding to SLC9A1 gene			[1]
TF Protein Name	Transcription factor JunD		Transcription Factor Info
Tissue	Bone marrow; Colon; Coronary artery; Embryo; Liver; Lung
Related DT Changes	Direct regulating
Experiment method	TF-transporter regulations were collected from ChIP-Seq datasets.
Detailed Description	Transcription factor JunD (JUND) can directly bind to the SLC9A1 gene, which in turn affects the expression or function of the drug transporter Sodium/hydrogen exchanger 1.
Class1.2: Basic helix-loop-helix factors		Click to Show/Hide the Full List of 12 TF(s) Regulating This DT
ARNT		Click to Show/Hide to Show 1 Transcriptional Phenomena
Transcriptional Phenomenon1	Activation of SLC9A1 gene in breast cancer condition			[7]
TF Protein Name	Aryl hydrocarbon receptor nuclear translocator		Transcription Factor Info
Affected Drug/Substrate	2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD)
Studied Phenotype	.
Related DT Changes	Up regulating
Detailed Description	Aryl hydrocarbon receptor nuclear translocator (ARNT) has been reported to activate the transcription of SLC9A1 gene in breast cancer condition, which leads to an increased expression of the drug transporter Sodium/hydrogen exchanger 1.
ASCL1		Click to Show/Hide to Show 1 Transcriptional Phenomena
Transcriptional Phenomenon1	Direct binding to SLC9A1 gene			[1]
TF Protein Name	Achaete-scute homolog 1		Transcription Factor Info
Tissue	Lung
Related DT Changes	Direct regulating
Experiment method	TF-transporter regulations were collected from ChIP-Seq datasets.
Detailed Description	Achaete-scute homolog 1 (ASCL1) can directly bind to the SLC9A1 gene, which in turn affects the expression or function of the drug transporter Sodium/hydrogen exchanger 1.
ASCL2		Click to Show/Hide to Show 1 Transcriptional Phenomena
Transcriptional Phenomenon1	Direct binding to SLC9A1 gene			[5]
TF Protein Name	Achaete-scute homolog 2		Transcription Factor Info
Tissue	Prostate
Related DT Changes	Direct regulating
Experiment method	TF-transporter regulations were collected from ChIP-Seq datasets.
Detailed Description	Achaete-scute homolog 2 (ASCL2) can directly bind to the SLC9A1 gene, which in turn affects the expression or function of the drug transporter Sodium/hydrogen exchanger 1.
BHLHE40		Click to Show/Hide to Show 1 Transcriptional Phenomena
Transcriptional Phenomenon1	Direct binding to SLC9A1 gene			[3]
TF Protein Name	Class E basic helix-loop-helix protein 40		Transcription Factor Info
Tissue	Bone marrow
Related DT Changes	Direct regulating
Experiment method	TF-transporter regulations were collected from ChIP-Seq datasets.
Detailed Description	Class E basic helix-loop-helix protein 40 (BHLHE40) can directly bind to the SLC9A1 gene, which in turn affects the expression or function of the drug transporter Sodium/hydrogen exchanger 1.
HIF1A		Click to Show/Hide to Show 1 Transcriptional Phenomena
Transcriptional Phenomenon1	Activation of SLC9A1 gene in hypoxic pulmonary hypertension condition			[8]
TF Protein Name	Hypoxia-inducible factor 1-alpha		Transcription Factor Info
Studied Phenotype	Hypoxic pulmonary hypertension [ICD11: BB01.2]
Tissue	Intrapulmonary artery
Related DT Changes	Up regulating
Experimental Material	Wistar rats
Detailed Description	Hypoxia-inducible factor 1-alpha (HIF1A) has been reported to activate the transcription of SLC9A1 gene in hypoxic pulmonary hypertension condition, which leads to an increased expression of the drug transporter Sodium/hydrogen exchanger 1.
MITF		Click to Show/Hide to Show 1 Transcriptional Phenomena
Transcriptional Phenomenon1	Activation of SLC9A1 gene in melanoma condition			[9]
TF Protein Name	Microphthalmia-associated transcription factor		Transcription Factor Info
Studied Phenotype	.
Related DT Changes	Up regulating
Detailed Description	Microphthalmia-associated transcription factor (MITF) has been reported to activate the transcription of SLC9A1 gene in melanoma condition, which leads to an increased expression of the drug transporter Sodium/hydrogen exchanger 1.
MYC		Click to Show/Hide to Show 2 Transcriptional Phenomena
Transcriptional Phenomenon1	Repression of SLC9A1 gene in Burkitt lymphoma condition			[10]
TF Protein Name	Myc proto-oncogene protein		Transcription Factor Info
Studied Phenotype	.
Related DT Changes	Down regulating
Detailed Description	Myc proto-oncogene protein (MYC) has been reported to repress the transcription of SLC9A1 gene in Burkitt lymphoma condition, which leads to a decreased expression of the drug transporter Sodium/hydrogen exchanger 1.
Transcriptional Phenomenon2	Binding to SLC9A1 gene in embryonic stem cells condition			[11]
TF Protein Name	Myc proto-oncogene protein		Transcription Factor Info
Related DT Changes	Direct regulating
Detailed Description	Myc proto-oncogene protein (MYC) has been reported to bind to the transcription of SLC9A1 gene in embryonic stem cells condition, which leads to an affected expression of the drug transporter Sodium/hydrogen exchanger 1.
MYOD1		Click to Show/Hide to Show 1 Transcriptional Phenomena
Transcriptional Phenomenon1	Direct binding to SLC9A1 gene			[3]
TF Protein Name	Myoblast determination protein 1		Transcription Factor Info
Tissue	Myotube
Related DT Changes	Direct regulating
Experiment method	TF-transporter regulations were collected from ChIP-Seq datasets.
Detailed Description	Myoblast determination protein 1 (MYOD1) can directly bind to the SLC9A1 gene, which in turn affects the expression or function of the drug transporter Sodium/hydrogen exchanger 1.
TCF12		Click to Show/Hide to Show 1 Transcriptional Phenomena
Transcriptional Phenomenon1	Direct binding to SLC9A1 gene			[3]
TF Protein Name	Transcription factor 12		Transcription Factor Info
Tissue	Blood; Brain; Breast; Embryo; Lung; Uterus
Related DT Changes	Direct regulating
Experiment method	TF-transporter regulations were collected from ChIP-Seq datasets.
Detailed Description	Transcription factor 12 (TCF12) can directly bind to the SLC9A1 gene, which in turn affects the expression or function of the drug transporter Sodium/hydrogen exchanger 1.
TCF21		Click to Show/Hide to Show 1 Transcriptional Phenomena
Transcriptional Phenomenon1	Direct binding to SLC9A1 gene			[4]
TF Protein Name	Transcription factor 21		Transcription Factor Info
Tissue	Coronary artery
Related DT Changes	Direct regulating
Experiment method	TF-transporter regulations were collected from ChIP-Seq datasets.
Detailed Description	Transcription factor 21 (TCF21) can directly bind to the SLC9A1 gene, which in turn affects the expression or function of the drug transporter Sodium/hydrogen exchanger 1.
TCF3		Click to Show/Hide to Show 1 Transcriptional Phenomena
Transcriptional Phenomenon1	Direct binding to SLC9A1 gene			[4]
TF Protein Name	Transcription factor E2-alpha		Transcription Factor Info
Tissue	Blood
Related DT Changes	Direct regulating
Experiment method	TF-transporter regulations were collected from ChIP-Seq datasets.
Detailed Description	Transcription factor E2-alpha (TCF3) can directly bind to the SLC9A1 gene, which in turn affects the expression or function of the drug transporter Sodium/hydrogen exchanger 1.
TFAP4		Click to Show/Hide to Show 1 Transcriptional Phenomena
Transcriptional Phenomenon1	Direct binding to SLC9A1 gene			[5]
TF Protein Name	Transcription factor AP-4		Transcription Factor Info
Tissue	Blood
Related DT Changes	Direct regulating
Experiment method	TF-transporter regulations were collected from ChIP-Seq datasets.
Detailed Description	Transcription factor AP-4 (TFAP4) can directly bind to the SLC9A1 gene, which in turn affects the expression or function of the drug transporter Sodium/hydrogen exchanger 1.
TF Superclass2: Zinc-coordinating DNA-binding domains
Class2.1: Nuclear receptors with C4 zinc fingers		Click to Show/Hide the Full List of 7 TF(s) Regulating This DT
ESRRA		Click to Show/Hide to Show 1 Transcriptional Phenomena
Transcriptional Phenomenon1	Direct binding to SLC9A1 gene			[5]
TF Protein Name	Steroid hormone receptor ERR1		Transcription Factor Info
Tissue	Colon
Related DT Changes	Direct regulating
Experiment method	TF-transporter regulations were collected from ChIP-Seq datasets.
Detailed Description	Steroid hormone receptor ERR1 (ESRRA) can directly bind to the SLC9A1 gene, which in turn affects the expression or function of the drug transporter Sodium/hydrogen exchanger 1.
NR2F2		Click to Show/Hide to Show 1 Transcriptional Phenomena
Transcriptional Phenomenon1	Direct binding to SLC9A1 gene			[3]
TF Protein Name	COUP transcription factor 2		Transcription Factor Info
Tissue	Breast
Related DT Changes	Direct regulating
Experiment method	TF-transporter regulations were collected from ChIP-Seq datasets.
Detailed Description	COUP transcription factor 2 (NR2F2) can directly bind to the SLC9A1 gene, which in turn affects the expression or function of the drug transporter Sodium/hydrogen exchanger 1.
PPARA		Click to Show/Hide to Show 1 Transcriptional Phenomena
Transcriptional Phenomenon1	Binding to SLC9A1 gene in cancer condition			[12]
TF Protein Name	Peroxisome proliferator-activated receptor alpha		Transcription Factor Info
Studied Phenotype	.
Related DT Changes	Direct regulating
Detailed Description	Peroxisome proliferator-activated receptor alpha (PPARA) has been reported to bind to the transcription of SLC9A1 gene in cancer condition, which leads to an affected expression of the drug transporter Sodium/hydrogen exchanger 1.
PPARD		Click to Show/Hide to Show 1 Transcriptional Phenomena
Transcriptional Phenomenon1	Repression of SLC9A1 gene in myofibroblasts condition			[13]
TF Protein Name	Peroxisome proliferator-activated receptor delta		Transcription Factor Info
Studied Phenotype	.
Related DT Changes	Down regulating
Detailed Description	Peroxisome proliferator-activated receptor delta (PPARD) has been reported to repress the transcription of SLC9A1 gene in myofibroblasts condition, which leads to a decreased expression of the drug transporter Sodium/hydrogen exchanger 1.
PPARG		Click to Show/Hide to Show 1 Transcriptional Phenomena
Transcriptional Phenomenon1	Repression of SLC9A1 gene in breast cancer condition			[14]
TF Protein Name	Peroxisome proliferator-activated receptor gamma		Transcription Factor Info
Studied Phenotype	Breast cancer [ICD11: 2C60-2C6Z]
Tissue	Breast
Related DT Changes	Down regulating
Experimental Material	Human invasive breast carcinoma of no special type cells (MCF-7)
Detailed Description	Peroxisome proliferator-activated receptor gamma (PPARG) has been reported to repress the transcription of SLC9A1 gene in breast cancer condition, which leads to a decreased expression of the drug transporter Sodium/hydrogen exchanger 1.
RXRA		Click to Show/Hide to Show 1 Transcriptional Phenomena
Transcriptional Phenomenon1	Direct binding to SLC9A1 gene			[3]
TF Protein Name	Retinoic acid receptor RXR-alpha		Transcription Factor Info
Tissue	Blood; Colon; Liver
Related DT Changes	Direct regulating
Experiment method	TF-transporter regulations were collected from ChIP-Seq datasets.
Detailed Description	Retinoic acid receptor RXR-alpha (RXRA) can directly bind to the SLC9A1 gene, which in turn affects the expression or function of the drug transporter Sodium/hydrogen exchanger 1.
RXRG		Click to Show/Hide to Show 1 Transcriptional Phenomena
Transcriptional Phenomenon1	Direct binding to SLC9A1 gene			[4]
TF Protein Name	Retinoic acid receptor RXR-gamma		Transcription Factor Info
Tissue	Blood
Related DT Changes	Direct regulating
Experiment method	TF-transporter regulations were collected from ChIP-Seq datasets.
Detailed Description	Retinoic acid receptor RXR-gamma (RXRG) can directly bind to the SLC9A1 gene, which in turn affects the expression or function of the drug transporter Sodium/hydrogen exchanger 1.
Class2.2: Other C4 zinc finger-type factors		Click to Show/Hide the Full List of 4 TF(s) Regulating This DT
GATA1		Click to Show/Hide to Show 1 Transcriptional Phenomena
Transcriptional Phenomenon1	Direct binding to SLC9A1 gene			[1]
TF Protein Name	Erythroid transcription factor		Transcription Factor Info
Tissue	Blood; Bone marrow; Liver
Related DT Changes	Direct regulating
Experiment method	TF-transporter regulations were collected from ChIP-Seq datasets.
Detailed Description	Erythroid transcription factor (GATA1) can directly bind to the SLC9A1 gene, which in turn affects the expression or function of the drug transporter Sodium/hydrogen exchanger 1.
GATA2		Click to Show/Hide to Show 2 Transcriptional Phenomena
Transcriptional Phenomenon1	Activation of SLC9A1 gene in hematopoiesis condition			[15]
TF Protein Name	Endothelial transcription factor GATA-2		Transcription Factor Info
Studied Phenotype	.
Related DT Changes	Up regulating
Detailed Description	Endothelial transcription factor GATA-2 (GATA2) has been reported to activate the transcription of SLC9A1 gene in hematopoiesis condition, which leads to an increased expression of the drug transporter Sodium/hydrogen exchanger 1.
Transcriptional Phenomenon2	Binding to SLC9A1 gene in health condition			[16]
TF Protein Name	Endothelial transcription factor GATA-2		Transcription Factor Info
Studied Phenotype	.
Related DT Changes	Direct regulating
Detailed Description	Endothelial transcription factor GATA-2 (GATA2) has been reported to bind to the transcription of SLC9A1 gene in health condition, which leads to an affected expression of the drug transporter Sodium/hydrogen exchanger 1.
GATA3		Click to Show/Hide to Show 1 Transcriptional Phenomena
Transcriptional Phenomenon1	Direct binding to SLC9A1 gene			[3]
TF Protein Name	Trans-acting T-cell-specific transcription factor GATA-3		Transcription Factor Info
Tissue	Blood; Brain; Breast; Lung
Related DT Changes	Direct regulating
Experiment method	TF-transporter regulations were collected from ChIP-Seq datasets.
Detailed Description	Trans-acting T-cell-specific transcription factor GATA-3 (GATA3) can directly bind to the SLC9A1 gene, which in turn affects the expression or function of the drug transporter Sodium/hydrogen exchanger 1.
GATA6		Click to Show/Hide to Show 1 Transcriptional Phenomena
Transcriptional Phenomenon1	Activation of SLC9A1 gene in gastric cancer condition			[17]
TF Protein Name	Transcription factor GATA-6		Transcription Factor Info
Studied Phenotype	.
Related DT Changes	Up regulating
Detailed Description	Transcription factor GATA-6 (GATA6) has been reported to activate the transcription of SLC9A1 gene in gastric cancer condition, which leads to an increased expression of the drug transporter Sodium/hydrogen exchanger 1.
Class2.3: C2H2 zinc finger factors		Click to Show/Hide the Full List of 12 TF(s) Regulating This DT
CTCF		Click to Show/Hide to Show 1 Transcriptional Phenomena
Transcriptional Phenomenon1	Direct binding to SLC9A1 gene			[3]
TF Protein Name	Transcriptional repressor CTCF		Transcription Factor Info
Tissue	Brain
Related DT Changes	Direct regulating
Experiment method	TF-transporter regulations were collected from ChIP-Seq datasets.
Detailed Description	Transcriptional repressor CTCF (CTCF) can directly bind to the SLC9A1 gene, which in turn affects the expression or function of the drug transporter Sodium/hydrogen exchanger 1.
EGR1		Click to Show/Hide to Show 2 Transcriptional Phenomena
Transcriptional Phenomenon1	Binding to SLC9A1 gene in erythroleukemia condition			[18]
TF Protein Name	Early growth response protein 1		Transcription Factor Info
Studied Phenotype	.
Related DT Changes	Direct regulating
Detailed Description	Early growth response protein 1 (EGR1) has been reported to bind to the transcription of SLC9A1 gene in erythroleukemia condition, which leads to an affected expression of the drug transporter Sodium/hydrogen exchanger 1.
Transcriptional Phenomenon2	Direct binding to SLC9A1 gene			[4]
TF Protein Name	Early growth response protein 1		Transcription Factor Info
Tissue	Blood; Bone marrow; Embryo
Related DT Changes	Direct regulating
Experiment method	TF-transporter regulations were collected from ChIP-Seq datasets.
Detailed Description	Early growth response protein 1 (EGR1) can directly bind to the SLC9A1 gene, which in turn affects the expression or function of the drug transporter Sodium/hydrogen exchanger 1.
KLF1		Click to Show/Hide to Show 1 Transcriptional Phenomena
Transcriptional Phenomenon1	Direct binding to SLC9A1 gene			[4]
TF Protein Name	Krueppel-like factor 1		Transcription Factor Info
Tissue	Blood
Related DT Changes	Direct regulating
Experiment method	TF-transporter regulations were collected from ChIP-Seq datasets.
Detailed Description	Krueppel-like factor 1 (KLF1) can directly bind to the SLC9A1 gene, which in turn affects the expression or function of the drug transporter Sodium/hydrogen exchanger 1.
KLF4		Click to Show/Hide to Show 1 Transcriptional Phenomena
Transcriptional Phenomenon1	Direct binding to SLC9A1 gene			[5]
TF Protein Name	Krueppel-like factor 4		Transcription Factor Info
Tissue	Foreskin; Skin
Related DT Changes	Direct regulating
Experiment method	TF-transporter regulations were collected from ChIP-Seq datasets.
Detailed Description	Krueppel-like factor 4 (KLF4) can directly bind to the SLC9A1 gene, which in turn affects the expression or function of the drug transporter Sodium/hydrogen exchanger 1.
KLF5		Click to Show/Hide to Show 1 Transcriptional Phenomena
Transcriptional Phenomenon1	Direct binding to SLC9A1 gene			[4]
TF Protein Name	Krueppel-like factor 5		Transcription Factor Info
Tissue	Colon; Pancreatic ductal; Stomach
Related DT Changes	Direct regulating
Experiment method	TF-transporter regulations were collected from ChIP-Seq datasets.
Detailed Description	Krueppel-like factor 5 (KLF5) can directly bind to the SLC9A1 gene, which in turn affects the expression or function of the drug transporter Sodium/hydrogen exchanger 1.
KLF9		Click to Show/Hide to Show 1 Transcriptional Phenomena
Transcriptional Phenomenon1	Direct binding to SLC9A1 gene			[5]
TF Protein Name	Krueppel-like factor 9		Transcription Factor Info
Related DT Changes	Direct regulating
Experiment method	TF-transporter regulations were collected from ChIP-Seq datasets.
Detailed Description	Krueppel-like factor 9 (KLF9) can directly bind to the SLC9A1 gene, which in turn affects the expression or function of the drug transporter Sodium/hydrogen exchanger 1.
MAZ		Click to Show/Hide to Show 1 Transcriptional Phenomena
Transcriptional Phenomenon1	Direct binding to SLC9A1 gene			[1]
TF Protein Name	Myc-associated zinc finger protein		Transcription Factor Info
Tissue	Blood; Bone marrow; Cervix; Liver; Lung
Related DT Changes	Direct regulating
Experiment method	TF-transporter regulations were collected from ChIP-Seq datasets.
Detailed Description	Myc-associated zinc finger protein (MAZ) can directly bind to the SLC9A1 gene, which in turn affects the expression or function of the drug transporter Sodium/hydrogen exchanger 1.
MECOM		Click to Show/Hide to Show 1 Transcriptional Phenomena
Transcriptional Phenomenon1	Direct binding to SLC9A1 gene			[1]
TF Protein Name	Histone-lysine N-methyltransferase MECOM		Transcription Factor Info
Tissue	Colon
Related DT Changes	Direct regulating
Experiment method	TF-transporter regulations were collected from ChIP-Seq datasets.
Detailed Description	Histone-lysine N-methyltransferase MECOM (MECOM) can directly bind to the SLC9A1 gene, which in turn affects the expression or function of the drug transporter Sodium/hydrogen exchanger 1.
WT1		Click to Show/Hide to Show 1 Transcriptional Phenomena
Transcriptional Phenomenon1	Activation of SLC9A1 gene in podocyte condition			[19]
TF Protein Name	Wilms tumor protein		Transcription Factor Info
Studied Phenotype	.
Related DT Changes	Up regulating
Detailed Description	Wilms tumor protein (WT1) has been reported to activate the transcription of SLC9A1 gene in podocyte condition, which leads to an increased expression of the drug transporter Sodium/hydrogen exchanger 1.
ZNF217		Click to Show/Hide to Show 1 Transcriptional Phenomena
Transcriptional Phenomenon1	Binding to SLC9A1 gene in breast cancer condition			[20]
TF Protein Name	Zinc finger protein 217		Transcription Factor Info
Studied Phenotype	.
Related DT Changes	Direct regulating
Detailed Description	Zinc finger protein 217 (ZNF217) has been reported to bind to the transcription of SLC9A1 gene in breast cancer condition, which leads to an affected expression of the drug transporter Sodium/hydrogen exchanger 1.
ZNF263		Click to Show/Hide to Show 1 Transcriptional Phenomena
Transcriptional Phenomenon1	Direct binding to SLC9A1 gene			[1]
TF Protein Name	Zinc finger protein 263		Transcription Factor Info
Tissue	Bone marrow; Kidney
Related DT Changes	Direct regulating
Experiment method	TF-transporter regulations were collected from ChIP-Seq datasets.
Detailed Description	Zinc finger protein 263 (ZNF263) can directly bind to the SLC9A1 gene, which in turn affects the expression or function of the drug transporter Sodium/hydrogen exchanger 1.
ZNF384		Click to Show/Hide to Show 1 Transcriptional Phenomena
Transcriptional Phenomenon1	Direct binding to SLC9A1 gene			[3]
TF Protein Name	Zinc finger protein 384		Transcription Factor Info
Tissue	Blood; Bone marrow
Related DT Changes	Direct regulating
Experiment method	TF-transporter regulations were collected from ChIP-Seq datasets.
Detailed Description	Zinc finger protein 384 (ZNF384) can directly bind to the SLC9A1 gene, which in turn affects the expression or function of the drug transporter Sodium/hydrogen exchanger 1.
Class2.9: C2CH THAP-type zinc finger factors		Click to Show/Hide the Full List of 1 TF(s) Regulating This DT
THAP1		Click to Show/Hide to Show 1 Transcriptional Phenomena
Transcriptional Phenomenon1	Direct binding to SLC9A1 gene			[5]
TF Protein Name	THAP domain-containing protein 1		Transcription Factor Info
Tissue	Bone marrow
Related DT Changes	Direct regulating
Experiment method	TF-transporter regulations were collected from ChIP-Seq datasets.
Detailed Description	THAP domain-containing protein 1 (THAP1) can directly bind to the SLC9A1 gene, which in turn affects the expression or function of the drug transporter Sodium/hydrogen exchanger 1.
TF Superclass3: Helix-turn-helix domains
Class3.1: Homeo domain factors		Click to Show/Hide the Full List of 3 TF(s) Regulating This DT
MEIS1		Click to Show/Hide to Show 1 Transcriptional Phenomena
Transcriptional Phenomenon1	Direct binding to SLC9A1 gene			[5]
TF Protein Name	Homeobox protein Meis1		Transcription Factor Info
Tissue	Bone marrow
Related DT Changes	Direct regulating
Experiment method	TF-transporter regulations were collected from ChIP-Seq datasets.
Detailed Description	Homeobox protein Meis1 (MEIS1) can directly bind to the SLC9A1 gene, which in turn affects the expression or function of the drug transporter Sodium/hydrogen exchanger 1.
PBX3		Click to Show/Hide to Show 1 Transcriptional Phenomena
Transcriptional Phenomenon1	Direct binding to SLC9A1 gene			[1]
TF Protein Name	Pre-B-cell leukemia transcription factor 3		Transcription Factor Info
Tissue	Blood; Brain; Lung
Related DT Changes	Direct regulating
Experiment method	TF-transporter regulations were collected from ChIP-Seq datasets.
Detailed Description	Pre-B-cell leukemia transcription factor 3 (PBX3) can directly bind to the SLC9A1 gene, which in turn affects the expression or function of the drug transporter Sodium/hydrogen exchanger 1.
POU2F1		Click to Show/Hide to Show 1 Transcriptional Phenomena
Transcriptional Phenomenon1	Direct binding to SLC9A1 gene			[3]
TF Protein Name	POU domain, class 2, transcription factor 1		Transcription Factor Info
Tissue	Blood
Related DT Changes	Direct regulating
Experiment method	TF-transporter regulations were collected from ChIP-Seq datasets.
Detailed Description	POU domain, class 2, transcription factor 1 (POU2F1) can directly bind to the SLC9A1 gene, which in turn affects the expression or function of the drug transporter Sodium/hydrogen exchanger 1.
Class3.3: Fork head / winged helix factors		Click to Show/Hide the Full List of 6 TF(s) Regulating This DT
E2F4		Click to Show/Hide to Show 1 Transcriptional Phenomena
Transcriptional Phenomenon1	Binding to SLC9A1 gene in health condition			[21]
TF Protein Name	Transcription factor E2F4		Transcription Factor Info
Studied Phenotype	.
Related DT Changes	Direct regulating
Detailed Description	Transcription factor E2F4 (E2F4) has been reported to bind to the transcription of SLC9A1 gene in health condition, which leads to an affected expression of the drug transporter Sodium/hydrogen exchanger 1.
E2F6		Click to Show/Hide to Show 1 Transcriptional Phenomena
Transcriptional Phenomenon1	Direct binding to SLC9A1 gene			[1]
TF Protein Name	Transcription factor E2F6		Transcription Factor Info
Tissue	Bone marrow; Embryo
Related DT Changes	Direct regulating
Experiment method	TF-transporter regulations were collected from ChIP-Seq datasets.
Detailed Description	Transcription factor E2F6 (E2F6) can directly bind to the SLC9A1 gene, which in turn affects the expression or function of the drug transporter Sodium/hydrogen exchanger 1.
E2F8		Click to Show/Hide to Show 1 Transcriptional Phenomena
Transcriptional Phenomenon1	Direct binding to SLC9A1 gene			[5]
TF Protein Name	Transcription factor E2F8		Transcription Factor Info
Tissue	Colon
Related DT Changes	Direct regulating
Experiment method	TF-transporter regulations were collected from ChIP-Seq datasets.
Detailed Description	Transcription factor E2F8 (E2F8) can directly bind to the SLC9A1 gene, which in turn affects the expression or function of the drug transporter Sodium/hydrogen exchanger 1.
FOXA1		Click to Show/Hide to Show 1 Transcriptional Phenomena
Transcriptional Phenomenon1	Direct binding to SLC9A1 gene			[4]
TF Protein Name	Hepatocyte nuclear factor 3-alpha		Transcription Factor Info
Tissue	Breast; Embryo; Liver; Lung; Pancreatic ductal; Prostate; Uterus
Related DT Changes	Direct regulating
Experiment method	TF-transporter regulations were collected from ChIP-Seq datasets.
Detailed Description	Hepatocyte nuclear factor 3-alpha (FOXA1) can directly bind to the SLC9A1 gene, which in turn affects the expression or function of the drug transporter Sodium/hydrogen exchanger 1.
FOXA2		Click to Show/Hide to Show 1 Transcriptional Phenomena
Transcriptional Phenomenon1	Direct binding to SLC9A1 gene			[5]
TF Protein Name	Hepatocyte nuclear factor 3-beta		Transcription Factor Info
Tissue	Colon
Related DT Changes	Direct regulating
Experiment method	TF-transporter regulations were collected from ChIP-Seq datasets.
Detailed Description	Hepatocyte nuclear factor 3-beta (FOXA2) can directly bind to the SLC9A1 gene, which in turn affects the expression or function of the drug transporter Sodium/hydrogen exchanger 1.
FOXP1		Click to Show/Hide to Show 2 Transcriptional Phenomena
Transcriptional Phenomenon1	Repression of SLC9A1 gene in embryonic stem cell condition			[22]
TF Protein Name	Forkhead box protein P1		Transcription Factor Info
Studied Phenotype	.
Related DT Changes	Down regulating
Detailed Description	Forkhead box protein P1 (FOXP1) has been reported to repress the transcription of SLC9A1 gene in embryonic stem cell condition, which leads to a decreased expression of the drug transporter Sodium/hydrogen exchanger 1.
Transcriptional Phenomenon2	Direct binding to SLC9A1 gene			[1]
TF Protein Name	Forkhead box protein P1		Transcription Factor Info
Tissue	Embryo; Prostate
Related DT Changes	Direct regulating
Experiment method	TF-transporter regulations were collected from ChIP-Seq datasets.
Detailed Description	Forkhead box protein P1 (FOXP1) can directly bind to the SLC9A1 gene, which in turn affects the expression or function of the drug transporter Sodium/hydrogen exchanger 1.
Class3.5: Tryptophan cluster factors		Click to Show/Hide the Full List of 9 TF(s) Regulating This DT
EHF		Click to Show/Hide to Show 1 Transcriptional Phenomena
Transcriptional Phenomenon1	Direct binding to SLC9A1 gene			[1]
TF Protein Name	ETS homologous factor		Transcription Factor Info
Tissue	Colon
Related DT Changes	Direct regulating
Experiment method	TF-transporter regulations were collected from ChIP-Seq datasets.
Detailed Description	ETS homologous factor (EHF) can directly bind to the SLC9A1 gene, which in turn affects the expression or function of the drug transporter Sodium/hydrogen exchanger 1.
ELF1		Click to Show/Hide to Show 1 Transcriptional Phenomena
Transcriptional Phenomenon1	Direct binding to SLC9A1 gene			[3]
TF Protein Name	ETS-related transcription factor Elf-1		Transcription Factor Info
Tissue	Blood; Bone marrow; Breast; Mesenchymal
Related DT Changes	Direct regulating
Experiment method	TF-transporter regulations were collected from ChIP-Seq datasets.
Detailed Description	ETS-related transcription factor Elf-1 (ELF1) can directly bind to the SLC9A1 gene, which in turn affects the expression or function of the drug transporter Sodium/hydrogen exchanger 1.
ETS1		Click to Show/Hide to Show 1 Transcriptional Phenomena
Transcriptional Phenomenon1	Direct binding to SLC9A1 gene			[3]
TF Protein Name	Protein C-ets-1		Transcription Factor Info
Tissue	Blood; Bone; Bone marrow; Kidney; Vein
Related DT Changes	Direct regulating
Experiment method	TF-transporter regulations were collected from ChIP-Seq datasets.
Detailed Description	Protein C-ets-1 (ETS1) can directly bind to the SLC9A1 gene, which in turn affects the expression or function of the drug transporter Sodium/hydrogen exchanger 1.
ETV7		Click to Show/Hide to Show 1 Transcriptional Phenomena
Transcriptional Phenomenon1	Direct binding to SLC9A1 gene			[4]
TF Protein Name	Transcription factor ETV7		Transcription Factor Info
Tissue	Colon
Related DT Changes	Direct regulating
Experiment method	TF-transporter regulations were collected from ChIP-Seq datasets.
Detailed Description	Transcription factor ETV7 (ETV7) can directly bind to the SLC9A1 gene, which in turn affects the expression or function of the drug transporter Sodium/hydrogen exchanger 1.
FLI1		Click to Show/Hide to Show 2 Transcriptional Phenomena
Transcriptional Phenomenon1	Binding to SLC9A1 gene in megakaryocytes condition			[23]
TF Protein Name	Friend leukemia integration 1 transcription factor		Transcription Factor Info
Related DT Changes	Direct regulating
Detailed Description	Friend leukemia integration 1 transcription factor (FLI1) has been reported to bind to the transcription of SLC9A1 gene in megakaryocytes condition, which leads to an affected expression of the drug transporter Sodium/hydrogen exchanger 1.
Transcriptional Phenomenon2	Direct binding to SLC9A1 gene			[5]
TF Protein Name	Friend leukemia integration 1 transcription factor		Transcription Factor Info
Tissue	Blood; Mesenchymal; Vein
Related DT Changes	Direct regulating
Experiment method	TF-transporter regulations were collected from ChIP-Seq datasets.
Detailed Description	Friend leukemia integration 1 transcription factor (FLI1) can directly bind to the SLC9A1 gene, which in turn affects the expression or function of the drug transporter Sodium/hydrogen exchanger 1.
GABPA		Click to Show/Hide to Show 1 Transcriptional Phenomena
Transcriptional Phenomenon1	Direct binding to SLC9A1 gene			[3]
TF Protein Name	GA-binding protein alpha chain		Transcription Factor Info
Tissue	Brain; Liver
Related DT Changes	Direct regulating
Experiment method	TF-transporter regulations were collected from ChIP-Seq datasets.
Detailed Description	GA-binding protein alpha chain (GABPA) can directly bind to the SLC9A1 gene, which in turn affects the expression or function of the drug transporter Sodium/hydrogen exchanger 1.
IRF1		Click to Show/Hide to Show 1 Transcriptional Phenomena
Transcriptional Phenomenon1	Direct binding to SLC9A1 gene			[1]
TF Protein Name	Interferon regulatory factor 1		Transcription Factor Info
Tissue	Aorta
Related DT Changes	Direct regulating
Experiment method	TF-transporter regulations were collected from ChIP-Seq datasets.
Detailed Description	Interferon regulatory factor 1 (IRF1) can directly bind to the SLC9A1 gene, which in turn affects the expression or function of the drug transporter Sodium/hydrogen exchanger 1.
MYB		Click to Show/Hide to Show 1 Transcriptional Phenomena
Transcriptional Phenomenon1	Direct binding to SLC9A1 gene			[3]
TF Protein Name	Transcriptional activator Myb		Transcription Factor Info
Tissue	Blood
Related DT Changes	Direct regulating
Experiment method	TF-transporter regulations were collected from ChIP-Seq datasets.
Detailed Description	Transcriptional activator Myb (MYB) can directly bind to the SLC9A1 gene, which in turn affects the expression or function of the drug transporter Sodium/hydrogen exchanger 1.
SPI1		Click to Show/Hide to Show 1 Transcriptional Phenomena
Transcriptional Phenomenon1	Direct binding to SLC9A1 gene			[4]
TF Protein Name	Transcription factor PU.1		Transcription Factor Info
Tissue	Adrenal gland; Blood; Bone marrow; Brain; Breast; Embryo; Foreskin; Heart; Intestine; Kidney; Lung; Muscle; Penis; Placenta; Renal cortex; Renal pelvis; Skin; Spinal cord; Stomach; Testes; Umbilical cord blood
Related DT Changes	Direct regulating
Experiment method	TF-transporter regulations were collected from ChIP-Seq datasets.
Detailed Description	Transcription factor PU.1 (SPI1) can directly bind to the SLC9A1 gene, which in turn affects the expression or function of the drug transporter Sodium/hydrogen exchanger 1.
Class3.6: TEA domain factors		Click to Show/Hide the Full List of 1 TF(s) Regulating This DT
TEAD4		Click to Show/Hide to Show 1 Transcriptional Phenomena
Transcriptional Phenomenon1	Direct binding to SLC9A1 gene			[4]
TF Protein Name	Transcriptional enhancer factor TEF-3		Transcription Factor Info
Tissue	Bone marrow; Liver; Uterus
Related DT Changes	Direct regulating
Experiment method	TF-transporter regulations were collected from ChIP-Seq datasets.
Detailed Description	Transcriptional enhancer factor TEF-3 (TEAD4) can directly bind to the SLC9A1 gene, which in turn affects the expression or function of the drug transporter Sodium/hydrogen exchanger 1.
Class3.7: ARID domain factors		Click to Show/Hide the Full List of 1 TF(s) Regulating This DT
KDM5B		Click to Show/Hide to Show 1 Transcriptional Phenomena
Transcriptional Phenomenon1	Direct binding to SLC9A1 gene			[4]
TF Protein Name	Lysine-specific demethylase 5B		Transcription Factor Info
Tissue	Bone marrow; Breast
Related DT Changes	Direct regulating
Experiment method	TF-transporter regulations were collected from ChIP-Seq datasets.
Detailed Description	Lysine-specific demethylase 5B (KDM5B) can directly bind to the SLC9A1 gene, which in turn affects the expression or function of the drug transporter Sodium/hydrogen exchanger 1.
TF Superclass5: alpha-Helices exposed by beta-structures
Class5.1: MADS box factors		Click to Show/Hide the Full List of 1 TF(s) Regulating This DT
SRF		Click to Show/Hide to Show 1 Transcriptional Phenomena
Transcriptional Phenomenon1	Direct binding to SLC9A1 gene			[5]
TF Protein Name	Serum response factor		Transcription Factor Info
Tissue	Embryo; Uterus
Related DT Changes	Direct regulating
Experiment method	TF-transporter regulations were collected from ChIP-Seq datasets.
Detailed Description	Serum response factor (SRF) can directly bind to the SLC9A1 gene, which in turn affects the expression or function of the drug transporter Sodium/hydrogen exchanger 1.
TF Superclass6: Immunoglobulin fold
Class6.1: Rel homology region factors		Click to Show/Hide the Full List of 1 TF(s) Regulating This DT
EBF1		Click to Show/Hide to Show 1 Transcriptional Phenomena
Transcriptional Phenomenon1	Direct binding to SLC9A1 gene			[5]
TF Protein Name	Transcription factor COE1		Transcription Factor Info
Tissue	Blood
Related DT Changes	Direct regulating
Experiment method	TF-transporter regulations were collected from ChIP-Seq datasets.
Detailed Description	Transcription factor COE1 (EBF1) can directly bind to the SLC9A1 gene, which in turn affects the expression or function of the drug transporter Sodium/hydrogen exchanger 1.
Class6.3: p53 domain factors		Click to Show/Hide the Full List of 1 TF(s) Regulating This DT
TP63		Click to Show/Hide to Show 1 Transcriptional Phenomena
Transcriptional Phenomenon1	Binding to SLC9A1 gene in health condition			[24]
TF Protein Name	Tumor protein 63		Transcription Factor Info
Studied Phenotype	.
Related DT Changes	Direct regulating
Detailed Description	Tumor protein 63 (TP63) has been reported to bind to the transcription of SLC9A1 gene in health condition, which leads to an affected expression of the drug transporter Sodium/hydrogen exchanger 1.
Class6.4: Runt domain factors		Click to Show/Hide the Full List of 2 TF(s) Regulating This DT
RUNX1		Click to Show/Hide to Show 1 Transcriptional Phenomena
Transcriptional Phenomenon1	Binding to SLC9A1 gene in megakaryocytes condition			[23]
TF Protein Name	Runt-related transcription factor 1		Transcription Factor Info
Related DT Changes	Direct regulating
Detailed Description	Runt-related transcription factor 1 (RUNX1) has been reported to bind to the transcription of SLC9A1 gene in megakaryocytes condition, which leads to an affected expression of the drug transporter Sodium/hydrogen exchanger 1.
RUNX3		Click to Show/Hide to Show 1 Transcriptional Phenomena
Transcriptional Phenomenon1	Direct binding to SLC9A1 gene			[4]
TF Protein Name	Runt-related transcription factor 3		Transcription Factor Info
Tissue	Blood
Related DT Changes	Direct regulating
Experiment method	TF-transporter regulations were collected from ChIP-Seq datasets.
Detailed Description	Runt-related transcription factor 3 (RUNX3) can directly bind to the SLC9A1 gene, which in turn affects the expression or function of the drug transporter Sodium/hydrogen exchanger 1.
Class6.7: Grainyhead domain factors		Click to Show/Hide the Full List of 2 TF(s) Regulating This DT
GRHL1		Click to Show/Hide to Show 1 Transcriptional Phenomena
Transcriptional Phenomenon1	Direct binding to SLC9A1 gene			[1]
TF Protein Name	Grainyhead-like protein 1 homolog		Transcription Factor Info
Tissue	Colon
Related DT Changes	Direct regulating
Experiment method	TF-transporter regulations were collected from ChIP-Seq datasets.
Detailed Description	Grainyhead-like protein 1 homolog (GRHL1) can directly bind to the SLC9A1 gene, which in turn affects the expression or function of the drug transporter Sodium/hydrogen exchanger 1.
GRHL2		Click to Show/Hide to Show 1 Transcriptional Phenomena
Transcriptional Phenomenon1	Direct binding to SLC9A1 gene			[3]
TF Protein Name	Grainyhead-like protein 2 homolog		Transcription Factor Info
Tissue	Breast; Bronchus; Ovary; Prostate
Related DT Changes	Direct regulating
Experiment method	TF-transporter regulations were collected from ChIP-Seq datasets.
Detailed Description	Grainyhead-like protein 2 homolog (GRHL2) can directly bind to the SLC9A1 gene, which in turn affects the expression or function of the drug transporter Sodium/hydrogen exchanger 1.
TF Superclass7: beta-Hairpin exposed by an alpha/beta-scaffold
Class7.1: SMAD/NF-1 DNA-binding domain factors		Click to Show/Hide the Full List of 1 TF(s) Regulating This DT
SMAD3		Click to Show/Hide to Show 1 Transcriptional Phenomena
Transcriptional Phenomenon1	Binding to SLC9A1 gene in health condition			[25]
TF Protein Name	Mothers against decapentaplegic homolog 3		Transcription Factor Info
Studied Phenotype	.
Related DT Changes	Direct regulating
Detailed Description	Mothers against decapentaplegic homolog 3 (SMAD3) has been reported to bind to the transcription of SLC9A1 gene in health condition, which leads to an affected expression of the drug transporter Sodium/hydrogen exchanger 1.
TF Superclass10: Yet undefined DNA-binding domains
Class10.1: Other factors		Click to Show/Hide the Full List of 2 TF(s) Regulating This DT
GTF2B		Click to Show/Hide to Show 1 Transcriptional Phenomena
Transcriptional Phenomenon1	Direct binding to SLC9A1 gene			[5]
TF Protein Name	Transcription initiation factor IIB		Transcription Factor Info
Tissue	Cervix; Lung
Related DT Changes	Direct regulating
Experiment method	TF-transporter regulations were collected from ChIP-Seq datasets.
Detailed Description	Transcription initiation factor IIB (GTF2B) can directly bind to the SLC9A1 gene, which in turn affects the expression or function of the drug transporter Sodium/hydrogen exchanger 1.
SETDB1		Click to Show/Hide to Show 1 Transcriptional Phenomena
Transcriptional Phenomenon1	Direct binding to SLC9A1 gene			[1]
TF Protein Name	Histone-lysine N-methyltransferase SETDB1		Transcription Factor Info
Tissue	Bone
Related DT Changes	Direct regulating
Experiment method	TF-transporter regulations were collected from ChIP-Seq datasets.
Detailed Description	Histone-lysine N-methyltransferase SETDB1 (SETDB1) can directly bind to the SLC9A1 gene, which in turn affects the expression or function of the drug transporter Sodium/hydrogen exchanger 1.

References
1	NCBI GEO: archive for functional genomics data sets--update. Nucleic Acids Res. 2013 Jan;41(D1):D991-5.
2	In vivo RNAi screen for BMI1 targets identifies TGF-BMP-ER stress pathways as key regulators of neural- and malignant glioma-stem cell homeostasis. Cancer Cell. 2013;23(5):660-76.
3	Closure of the NCBI SRA and implications for the long-term future of genomics data storage. Genome Biol. 2011;12(3):402.
4	The Encyclopedia of DNA elements (ENCODE): data portal update. Nucleic Acids Res. 2018 Jan 4;46(D1):D794-D801
5	hTFtarget: A Comprehensive Database for Regulations of Human Transcription Factors and Their Targets. Genomics Proteomics Bioinformatics. 2020 Apr;18(2):120-173. (ID:ENSG00000090020)
6	Characterization of TCF21 Downstream Target Regions Identifies a Transcriptional Network Linking Multiple Independent Coronary Artery Disease Loci. PLoS Genet. 2015;11(5):e1005202.
7	High-resolution genome-wide mapping of AHR and ARNT binding sites by ChIP-Seq. Toxicol Sci. 2012 Dec;130(2):349-61.
8	HIF-1 regulates hypoxic induction of NHE1 expression and alkalinization of intracellular pH in pulmonary arterial myocytes. Am J Physiol Lung Cell Mol Physiol. 2006 Nov;291(5):L941-9.
9	Essential role of microphthalmia transcription factor for DNA replication, mitosis and genomic stability in melanoma. Oncogene. 2011;30(20):2319-32.
10	Deep sequencing of MYC DNA-binding sites in Burkitt lymphoma. PLoS One. 2011;6(11):e26837.
11	Gene regulation and epigenetic remodeling in murine embryonic stem cells by c-Myc. PLoS One. 2009;4(11):e7839.
12	Computational identification and experimental validation of PPRE motifs in NHE1 and MnSOD genes of human. BMC Genomics. 2009;10 Suppl 3(Suppl 3):S5.
13	Genomewide analyses define different modes of transcriptional regulation by peroxisome proliferator-activated receptor. PLoS One. 2011;6(1):e16344.
14	Repression of NHE1 expression by PPARgamma activation is a potential new approach for specific inhibition of the growth of tumor cells in vitro and in vivo. Cancer Res. 2009 Nov 15;69(22):8636-44.
15	Discovering hematopoietic mechanisms through genome-wide analysis of GATA factor chromatin occupancy. Mol Cell. 2009;36(4):667-81.
16	Epigenetically coordinated GATA2 binding is necessary for endothelium-specific endomucin expression. EMBO J. 2011;30(13):2582-95.
17	Regulatory crosstalk between lineage-survival oncogenes KLF5, GATA4 and GATA6 cooperatively promotes gastric cancer development. Gut. 2015;64(5):707-19.
18	Global analysis of in vivo EGR1-binding sites in erythroleukemia cell using chromatin immunoprecipitation and massively parallel sequencing. Electrophoresis. 2010;31(17):2936-43.
19	Alternatively spliced isoforms of WT1 control podocyte-specific gene expression. Kidney Int. 2015;88(2):321-31.
20	Global analysis of ZNF217 chromatin occupancy in the breast cancer cell genome reveals an association with ERalpha. BMC Genomics. 2014;15(1):520.
21	Wide-ranging functions of E2F4 in transcriptional activation and repression revealed by genome-wide analysis. Nucleic Acids Res. 2011;39(9):3558-73.
22	An alternative splicing switch regulates embryonic stem cell pluripotency and reprogramming. Cell. 2011;147(1):132-46.
23	Genome-wide analysis of simultaneous GATA1/2, RUNX1, FLI1, and SCL binding in megakaryocytes identifies hematopoietic regulators. Dev Cell. 2011;20(5):597-609.
24	Genome-wide analysis of p63 binding sites identifies AP-2 factors as co-regulators of epidermal differentiation. Nucleic Acids Res. 2012;40(15):7190-206.
25	Chromatin immunoprecipitation on microarray analysis of Smad2/3 binding sites reveals roles of ETS1 and TFAP2A in transforming growth factor beta signaling. Mol Cell Biol. 2009;29(1):172-86.

If you find any error in data or bug in web service, please kindly report it to Dr. Li and Dr. Fu.

Detail Information of Transcriptional Regulations

Visitor Map

Correspondence