Detail Information of Transcriptional Regulations

General Information of Drug Transporter (DT)
DT ID DTD0326 Transporter Info
Gene Name SLC38A1
Transporter Name Sodium-coupled neutral amino acid transporter 1
Gene ID
81539
UniProt ID
Q9H2H9

Transcriptional Regulation of This DT (TSR)

TF Superclass1: Basic domains

      Class1.1: Basic leucine zipper factors

Click to Show/Hide the Full List of 8 TF(s) Regulating This DT

        ATF2 

Click to Show/Hide to Show 1 Transcriptional Phenomena      

       Transcriptional Phenomenon1

 Direct binding to SLC38A1 gene [1]

TF Protein Name

 Cyclic AMP-dependent transcription factor ATF-2 Transcription Factor Info

Tissue

 Blood; Embryo

Related DT Changes

 Direct regulating

Experiment method

 TF-transporter regulations were collected from ChIP-Seq datasets.

Detailed Description

 Cyclic AMP-dependent transcription factor ATF-2 (ATF2) can directly bind to the SLC38A1 gene, which in turn affects the expression or function of the drug transporter Sodium-coupled neutral amino acid transporter 1.

        ATF3 

Click to Show/Hide to Show 1 Transcriptional Phenomena      

       Transcriptional Phenomenon1

 Direct binding to SLC38A1 gene [1]

TF Protein Name

 Cyclic AMP-dependent transcription factor ATF-3 Transcription Factor Info

Tissue

 Bone marrow; Colon

Related DT Changes

 Direct regulating

Experiment method

 TF-transporter regulations were collected from ChIP-Seq datasets.

Detailed Description

 Cyclic AMP-dependent transcription factor ATF-3 (ATF3) can directly bind to the SLC38A1 gene, which in turn affects the expression or function of the drug transporter Sodium-coupled neutral amino acid transporter 1.

        BATF 

Click to Show/Hide to Show 1 Transcriptional Phenomena      

       Transcriptional Phenomenon1

 Direct binding to SLC38A1 gene [2]

TF Protein Name

 Basic leucine zipper transcriptional factor ATF-like Transcription Factor Info

Tissue

 Blood

Related DT Changes

 Direct regulating

Experiment method

 TF-transporter regulations were collected from ChIP-Seq datasets.

Detailed Description

 Basic leucine zipper transcriptional factor ATF-like (BATF) can directly bind to the SLC38A1 gene, which in turn affects the expression or function of the drug transporter Sodium-coupled neutral amino acid transporter 1.

        CEBPA 

Click to Show/Hide to Show 1 Transcriptional Phenomena      

       Transcriptional Phenomenon1

 Direct binding to SLC38A1 gene [2]

TF Protein Name

 CCAAT/enhancer-binding protein alpha Transcription Factor Info

Tissue

 Embryo

Related DT Changes

 Direct regulating

Experiment method

 TF-transporter regulations were collected from ChIP-Seq datasets.

Detailed Description

 CCAAT/enhancer-binding protein alpha (CEBPA) can directly bind to the SLC38A1 gene, which in turn affects the expression or function of the drug transporter Sodium-coupled neutral amino acid transporter 1.

        CEBPB 

Click to Show/Hide to Show 1 Transcriptional Phenomena      

       Transcriptional Phenomenon1

 Direct binding to SLC38A1 gene [3]

TF Protein Name

 CCAAT/enhancer-binding protein beta Transcription Factor Info

Tissue

 Blood

Related DT Changes

 Direct regulating

Experiment method

 TF-transporter regulations were collected from ChIP-Seq datasets.

Detailed Description

 CCAAT/enhancer-binding protein beta (CEBPB) can directly bind to the SLC38A1 gene, which in turn affects the expression or function of the drug transporter Sodium-coupled neutral amino acid transporter 1.

        CEBPD 

Click to Show/Hide to Show 1 Transcriptional Phenomena      

       Transcriptional Phenomenon1

 Direct binding to SLC38A1 gene [4]

TF Protein Name

 CCAAT/enhancer-binding protein delta Transcription Factor Info

Tissue

 Aorta

Related DT Changes

 Direct regulating

Experiment method

 TF-transporter regulations were collected from ChIP-Seq datasets.

Detailed Description

 CCAAT/enhancer-binding protein delta (CEBPD) can directly bind to the SLC38A1 gene, which in turn affects the expression or function of the drug transporter Sodium-coupled neutral amino acid transporter 1.

        CREB1 

Click to Show/Hide to Show 3 Transcriptional Phenomena      

       Transcriptional Phenomenon1

 Activation of SLC38A1 gene in glioma condition [5]

TF Protein Name

 Cyclic AMP-responsive element-binding protein 1 Transcription Factor Info

Studied Phenotype

 Glioma [ICD11: 2A00.0]

Tissue

 Brain

Related DT Changes

 Up regulating

Experimental Material

 Wistar rats

Detailed Description

 Cyclic AMP-responsive element-binding protein 1 (CREB1) has been reported to activate the transcription of SLC38A1 gene in glioma condition, which leads to an increased expression of the drug transporter Sodium-coupled neutral amino acid transporter 1.

       Transcriptional Phenomenon2

 Activation of SLC38A1 gene in health condition [6]

TF Protein Name

 Cyclic AMP-responsive element-binding protein 1 Transcription Factor Info

Studied Phenotype

 Heallth [ICD11: N.A]

Tissue

 Liver

Related DT Changes

 Up regulating

Experimental Material

 Wistar rats

Detailed Description

 Cyclic AMP-responsive element-binding protein 1 (CREB1) has been reported to activate the transcription of SLC38A1 gene in health condition, which leads to an increased expression of the drug transporter Sodium-coupled neutral amino acid transporter 1.

       Transcriptional Phenomenon3

 Direct binding to SLC38A1 gene [1]

TF Protein Name

 Cyclic AMP-responsive element-binding protein 1 Transcription Factor Info

Tissue

 Blood; Embryo; Liver

Related DT Changes

 Direct regulating

Experiment method

 TF-transporter regulations were collected from ChIP-Seq datasets.

Detailed Description

 Cyclic AMP-responsive element-binding protein 1 (CREB1) can directly bind to the SLC38A1 gene, which in turn affects the expression or function of the drug transporter Sodium-coupled neutral amino acid transporter 1.

        JUND 

Click to Show/Hide to Show 1 Transcriptional Phenomena      

       Transcriptional Phenomenon1

 Direct binding to SLC38A1 gene [3]

TF Protein Name

 Transcription factor JunD Transcription Factor Info

Tissue

 Bone marrow; Brain; Breast; Cervix; Colon; Coronary artery; Embryo; Liver; Lung; Prostate

Related DT Changes

 Direct regulating

Experiment method

 TF-transporter regulations were collected from ChIP-Seq datasets.

Detailed Description

 Transcription factor JunD (JUND) can directly bind to the SLC38A1 gene, which in turn affects the expression or function of the drug transporter Sodium-coupled neutral amino acid transporter 1.

      Class1.2: Basic helix-loop-helix factors

Click to Show/Hide the Full List of 9 TF(s) Regulating This DT

        ARNT 

Click to Show/Hide to Show 2 Transcriptional Phenomena      

       Transcriptional Phenomenon1

 Activation of SLC38A1 gene in breast cancer condition [7]

TF Protein Name

 Aryl hydrocarbon receptor nuclear translocator Transcription Factor Info

Affected Drug/Substrate

 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD)

Studied Phenotype

 .

Related DT Changes

 Up regulating

Detailed Description

 Aryl hydrocarbon receptor nuclear translocator (ARNT) has been reported to activate the transcription of SLC38A1 gene in breast cancer condition, which leads to an increased expression of the drug transporter Sodium-coupled neutral amino acid transporter 1.

       Transcriptional Phenomenon2

 Direct binding to SLC38A1 gene [3]

TF Protein Name

 Aryl hydrocarbon receptor nuclear translocator Transcription Factor Info

Tissue

 Breast

Related DT Changes

 Direct regulating

Experiment method

 TF-transporter regulations were collected from ChIP-Seq datasets.

Detailed Description

 Aryl hydrocarbon receptor nuclear translocator (ARNT) can directly bind to the SLC38A1 gene, which in turn affects the expression or function of the drug transporter Sodium-coupled neutral amino acid transporter 1.

        ASCL1 

Click to Show/Hide to Show 1 Transcriptional Phenomena      

       Transcriptional Phenomenon1

 Direct binding to SLC38A1 gene [4]

TF Protein Name

 Achaete-scute homolog 1 Transcription Factor Info

Tissue

 Lung

Related DT Changes

 Direct regulating

Experiment method

 TF-transporter regulations were collected from ChIP-Seq datasets.

Detailed Description

 Achaete-scute homolog 1 (ASCL1) can directly bind to the SLC38A1 gene, which in turn affects the expression or function of the drug transporter Sodium-coupled neutral amino acid transporter 1.

        HIF1A 

Click to Show/Hide to Show 2 Transcriptional Phenomena      

       Transcriptional Phenomenon1

 Activation of SLC38A1 gene in obesity condition [8]

TF Protein Name

 Hypoxia-inducible factor 1-alpha Transcription Factor Info

Studied Phenotype

 Obesity [ICD11: 5B81]

Tissue

 Brown adipose tissue

Related DT Changes

 Up regulating

Experimental Material

 C57BL/6 mice

Detailed Description

 Hypoxia-inducible factor 1-alpha (HIF1A) has been reported to activate the transcription of SLC38A1 gene in obesity condition, which leads to an increased expression of the drug transporter Sodium-coupled neutral amino acid transporter 1.

       Transcriptional Phenomenon2

 Activation of SLC38A1 gene in intrauterine growth restrictio condition [9]

TF Protein Name

 Hypoxia-inducible factor 1-alpha Transcription Factor Info

Studied Phenotype

 Intrauterine growth restrictio [ICD11: KA20.1]

Tissue

 Trophoderm

Related DT Changes

 Up regulating

Experimental Material

 Human gestational choriocarcinoma cells (HTR-8)

Detailed Description

 Hypoxia-inducible factor 1-alpha (HIF1A) has been reported to activate the transcription of SLC38A1 gene in intrauterine growth restrictio condition, which leads to an increased expression of the drug transporter Sodium-coupled neutral amino acid transporter 1.

        LYL1 

Click to Show/Hide to Show 1 Transcriptional Phenomena      

       Transcriptional Phenomenon1

 Direct binding to SLC38A1 gene [4]

TF Protein Name

 Protein lyl-1 Transcription Factor Info

Tissue

 Blood; Colon

Related DT Changes

 Direct regulating

Experiment method

 TF-transporter regulations were collected from ChIP-Seq datasets.

Detailed Description

 Protein lyl-1 (LYL1) can directly bind to the SLC38A1 gene, which in turn affects the expression or function of the drug transporter Sodium-coupled neutral amino acid transporter 1.

        MYC 

Click to Show/Hide to Show 1 Transcriptional Phenomena      

       Transcriptional Phenomenon1

 Binding to SLC38A1 gene in embryonic stem cells condition [10]

TF Protein Name

 Myc proto-oncogene protein Transcription Factor Info

Related DT Changes

 Direct regulating

Detailed Description

 Myc proto-oncogene protein (MYC) has been reported to bind to the transcription of SLC38A1 gene in embryonic stem cells condition, which leads to an affected expression of the drug transporter Sodium-coupled neutral amino acid transporter 1.

        MYOD1 

Click to Show/Hide to Show 1 Transcriptional Phenomena      

       Transcriptional Phenomenon1

 Direct binding to SLC38A1 gene [2]

TF Protein Name

 Myoblast determination protein 1 Transcription Factor Info

Tissue

 Myotube

Related DT Changes

 Direct regulating

Experiment method

 TF-transporter regulations were collected from ChIP-Seq datasets.

Detailed Description

 Myoblast determination protein 1 (MYOD1) can directly bind to the SLC38A1 gene, which in turn affects the expression or function of the drug transporter Sodium-coupled neutral amino acid transporter 1.

        TCF12 

Click to Show/Hide to Show 1 Transcriptional Phenomena      

       Transcriptional Phenomenon1

 Direct binding to SLC38A1 gene [1]

TF Protein Name

 Transcription factor 12 Transcription Factor Info

Tissue

 Blood; Breast; Embryo; Lung; Uterus

Related DT Changes

 Direct regulating

Experiment method

 TF-transporter regulations were collected from ChIP-Seq datasets.

Detailed Description

 Transcription factor 12 (TCF12) can directly bind to the SLC38A1 gene, which in turn affects the expression or function of the drug transporter Sodium-coupled neutral amino acid transporter 1.

        USF1 

Click to Show/Hide to Show 1 Transcriptional Phenomena      

       Transcriptional Phenomenon1

 Direct binding to SLC38A1 gene [3]

TF Protein Name

 Upstream stimulatory factor 1 Transcription Factor Info

Tissue

 Blood; Bone marrow; Brain; Colon; Embryo; Liver; Lung; Uterus

Related DT Changes

 Direct regulating

Experiment method

 TF-transporter regulations were collected from ChIP-Seq datasets.

Detailed Description

 Upstream stimulatory factor 1 (USF1) can directly bind to the SLC38A1 gene, which in turn affects the expression or function of the drug transporter Sodium-coupled neutral amino acid transporter 1.

        USF2 

Click to Show/Hide to Show 1 Transcriptional Phenomena      

       Transcriptional Phenomenon1

 Direct binding to SLC38A1 gene [4]

TF Protein Name

 Upstream stimulatory factor 2 Transcription Factor Info

Tissue

 Blood; Cervix; Embryo; Liver

Related DT Changes

 Direct regulating

Experiment method

 TF-transporter regulations were collected from ChIP-Seq datasets.

Detailed Description

 Upstream stimulatory factor 2 (USF2) can directly bind to the SLC38A1 gene, which in turn affects the expression or function of the drug transporter Sodium-coupled neutral amino acid transporter 1.

      Class1.3: Basic helix-span-helix factors

Click to Show/Hide the Full List of 2 TF(s) Regulating This DT

        TFAP2A 

Click to Show/Hide to Show 1 Transcriptional Phenomena      

       Transcriptional Phenomenon1

 Binding to SLC38A1 gene in health condition [11]

TF Protein Name

 Transcription factor AP-2-alpha Transcription Factor Info

Studied Phenotype

 .

Related DT Changes

 Direct regulating

Detailed Description

 Transcription factor AP-2-alpha (TFAP2A) has been reported to bind to the transcription of SLC38A1 gene in health condition, which leads to an affected expression of the drug transporter Sodium-coupled neutral amino acid transporter 1.

        TFAP2C 

Click to Show/Hide to Show 2 Transcriptional Phenomena      

       Transcriptional Phenomenon1

 Activation of SLC38A1 gene in breast cancer condition [12]

TF Protein Name

 Transcription factor AP-2 gamma Transcription Factor Info

Studied Phenotype

 .

Related DT Changes

 Up regulating

Detailed Description

 Transcription factor AP-2 gamma (TFAP2C) has been reported to activate the transcription of SLC38A1 gene in breast cancer condition, which leads to an increased expression of the drug transporter Sodium-coupled neutral amino acid transporter 1.

       Transcriptional Phenomenon2

 Direct binding to SLC38A1 gene [2]

TF Protein Name

 Transcription factor AP-2 gamma Transcription Factor Info

Tissue

 Breast

Related DT Changes

 Direct regulating

Experiment method

 TF-transporter regulations were collected from ChIP-Seq datasets.

Detailed Description

 Transcription factor AP-2 gamma (TFAP2C) can directly bind to the SLC38A1 gene, which in turn affects the expression or function of the drug transporter Sodium-coupled neutral amino acid transporter 1.

TF Superclass2: Zinc-coordinating DNA-binding domains

      Class2.1: Nuclear receptors with C4 zinc fingers

Click to Show/Hide the Full List of 6 TF(s) Regulating This DT

        AR 

Click to Show/Hide to Show 2 Transcriptional Phenomena      

       Transcriptional Phenomenon1

 Direct binding to SLC38A1 gene [13]

TF Protein Name

 Androgen receptor Transcription Factor Info

Related DT Changes

 Direct regulating

Detailed Description

 Androgen receptor (AR) has been reported to bind to the transcription of SLC38A1 gene in . condition, which leads to a affected expression of the drug transporter Sodium-coupled neutral amino acid transporter 1.

       Transcriptional Phenomenon2

 Direct binding to SLC38A1 gene [1]

TF Protein Name

 Androgen receptor Transcription Factor Info

Tissue

 Breast; Cervix; Kidney; Prostate

Related DT Changes

 Direct regulating

Experiment method

 TF-transporter regulations were collected from ChIP-Seq datasets.

Detailed Description

 Androgen receptor (AR) can directly bind to the SLC38A1 gene, which in turn affects the expression or function of the drug transporter Sodium-coupled neutral amino acid transporter 1.

        HNF4A 

Click to Show/Hide to Show 2 Transcriptional Phenomena      

       Transcriptional Phenomenon1

 Binding to SLC38A1 gene in health condition [14]

TF Protein Name

 Hepatocyte nuclear factor 4-alpha Transcription Factor Info

Studied Phenotype

 .

Related DT Changes

 Direct regulating

Detailed Description

 Hepatocyte nuclear factor 4-alpha (HNF4A) has been reported to bind to the transcription of SLC38A1 gene in health condition, which leads to an affected expression of the drug transporter Sodium-coupled neutral amino acid transporter 1.

       Transcriptional Phenomenon2

 Binding to SLC38A1 gene in health condition [15]

TF Protein Name

 Hepatocyte nuclear factor 4-alpha Transcription Factor Info

Studied Phenotype

 .

Related DT Changes

 Direct regulating

Detailed Description

 Hepatocyte nuclear factor 4-alpha (HNF4A) has been reported to bind to the transcription of SLC38A1 gene in health condition, which leads to an affected expression of the drug transporter Sodium-coupled neutral amino acid transporter 1.

        NR2F2 

Click to Show/Hide to Show 1 Transcriptional Phenomena      

       Transcriptional Phenomenon1

 Direct binding to SLC38A1 gene [4]

TF Protein Name

 COUP transcription factor 2 Transcription Factor Info

Tissue

 Breast

Related DT Changes

 Direct regulating

Experiment method

 TF-transporter regulations were collected from ChIP-Seq datasets.

Detailed Description

 COUP transcription factor 2 (NR2F2) can directly bind to the SLC38A1 gene, which in turn affects the expression or function of the drug transporter Sodium-coupled neutral amino acid transporter 1.

        PGR 

Click to Show/Hide to Show 1 Transcriptional Phenomena      

       Transcriptional Phenomenon1

 Direct binding to SLC38A1 gene [4]

TF Protein Name

 Progesterone receptor Transcription Factor Info

Tissue

 Breast

Related DT Changes

 Direct regulating

Experiment method

 TF-transporter regulations were collected from ChIP-Seq datasets.

Detailed Description

 Progesterone receptor (PGR) can directly bind to the SLC38A1 gene, which in turn affects the expression or function of the drug transporter Sodium-coupled neutral amino acid transporter 1.

        PPARD 

Click to Show/Hide to Show 1 Transcriptional Phenomena      

       Transcriptional Phenomenon1

 Repression of SLC38A1 gene in myofibroblast condition [16]

TF Protein Name

 Peroxisome proliferator-activated receptor delta Transcription Factor Info

Studied Phenotype

 .

Related DT Changes

 Down regulating

Detailed Description

 Peroxisome proliferator-activated receptor delta (PPARD) has been reported to repress the transcription of SLC38A1 gene in myofibroblast condition, which leads to a decreased expression of the drug transporter Sodium-coupled neutral amino acid transporter 1.

        PPARG 

Click to Show/Hide to Show 1 Transcriptional Phenomena      

       Transcriptional Phenomenon1

 Repression of SLC38A1 gene in health condition [17]

TF Protein Name

 Peroxisome proliferator-activated receptor gamma Transcription Factor Info

Studied Phenotype

 Heallth [ICD11: N.A]

Tissue

 Uterine horn

Related DT Changes

 Down regulating

Experimental Material

 Polish Landrace-Duroc hybrid pigs

Detailed Description

 Peroxisome proliferator-activated receptor gamma (PPARG) has been reported to repress the transcription of SLC38A1 gene in health condition, which leads to a decreased expression of the drug transporter Sodium-coupled neutral amino acid transporter 1.

      Class2.2: Other C4 zinc finger-type factors

Click to Show/Hide the Full List of 3 TF(s) Regulating This DT

        GATA1 

Click to Show/Hide to Show 1 Transcriptional Phenomena      

       Transcriptional Phenomenon1

 Direct binding to SLC38A1 gene [3]

TF Protein Name

 Erythroid transcription factor Transcription Factor Info

Tissue

 Blood; Bone marrow

Related DT Changes

 Direct regulating

Experiment method

 TF-transporter regulations were collected from ChIP-Seq datasets.

Detailed Description

 Erythroid transcription factor (GATA1) can directly bind to the SLC38A1 gene, which in turn affects the expression or function of the drug transporter Sodium-coupled neutral amino acid transporter 1.

        GATA3 

Click to Show/Hide to Show 1 Transcriptional Phenomena      

       Transcriptional Phenomenon1

 Direct binding to SLC38A1 gene [4]

TF Protein Name

 Trans-acting T-cell-specific transcription factor GATA-3 Transcription Factor Info

Tissue

 Blood; Breast

Related DT Changes

 Direct regulating

Experiment method

 TF-transporter regulations were collected from ChIP-Seq datasets.

Detailed Description

 Trans-acting T-cell-specific transcription factor GATA-3 (GATA3) can directly bind to the SLC38A1 gene, which in turn affects the expression or function of the drug transporter Sodium-coupled neutral amino acid transporter 1.

        GATA4 

Click to Show/Hide to Show 2 Transcriptional Phenomena      

       Transcriptional Phenomenon1

 Activation of SLC38A1 gene in gastric cancer condition [18]

TF Protein Name

 Transcription factor GATA-4 Transcription Factor Info

Affected Drug/Substrate

 Metformin

Studied Phenotype

 .

Related DT Changes

 Up regulating

Detailed Description

 Transcription factor GATA-4 (GATA4) has been reported to activate the transcription of SLC38A1 gene in gastric cancer condition, which leads to an increased expression of the drug transporter Sodium-coupled neutral amino acid transporter 1.

       Transcriptional Phenomenon2

 Direct binding to SLC38A1 gene [1]

TF Protein Name

 Transcription factor GATA-4 Transcription Factor Info

Tissue

 Heart

Related DT Changes

 Direct regulating

Experiment method

 TF-transporter regulations were collected from ChIP-Seq datasets.

Detailed Description

 Transcription factor GATA-4 (GATA4) can directly bind to the SLC38A1 gene, which in turn affects the expression or function of the drug transporter Sodium-coupled neutral amino acid transporter 1.

      Class2.3: C2H2 zinc finger factors

Click to Show/Hide the Full List of 8 TF(s) Regulating This DT

        BCL6 

Click to Show/Hide to Show 1 Transcriptional Phenomena      

       Transcriptional Phenomenon1

 Activation of SLC38A1 gene in health condition [19]

TF Protein Name

 B-cell lymphoma 6 protein Transcription Factor Info

Studied Phenotype

 .

Related DT Changes

 Up regulating

Detailed Description

 B-cell lymphoma 6 protein (BCL6) has been reported to activate the transcription of SLC38A1 gene in health condition, which leads to an increased expression of the drug transporter Sodium-coupled neutral amino acid transporter 1.

        EGR1 

Click to Show/Hide to Show 1 Transcriptional Phenomena      

       Transcriptional Phenomenon1

 Direct binding to SLC38A1 gene [2]

TF Protein Name

 Early growth response protein 1 Transcription Factor Info

Tissue

 Blood; Bone marrow; Uterus

Related DT Changes

 Direct regulating

Experiment method

 TF-transporter regulations were collected from ChIP-Seq datasets.

Detailed Description

 Early growth response protein 1 (EGR1) can directly bind to the SLC38A1 gene, which in turn affects the expression or function of the drug transporter Sodium-coupled neutral amino acid transporter 1.

        KLF4 

Click to Show/Hide to Show 1 Transcriptional Phenomena      

       Transcriptional Phenomenon1

 Direct binding to SLC38A1 gene [2]

TF Protein Name

 Krueppel-like factor 4 Transcription Factor Info

Tissue

 Breast; Foreskin; Pancreatic ductal; Skin

Related DT Changes

 Direct regulating

Experiment method

 TF-transporter regulations were collected from ChIP-Seq datasets.

Detailed Description

 Krueppel-like factor 4 (KLF4) can directly bind to the SLC38A1 gene, which in turn affects the expression or function of the drug transporter Sodium-coupled neutral amino acid transporter 1.

        KLF5 

Click to Show/Hide to Show 1 Transcriptional Phenomena      

       Transcriptional Phenomenon1

 Direct binding to SLC38A1 gene [2]

TF Protein Name

 Krueppel-like factor 5 Transcription Factor Info

Tissue

 Colon; Pancreatic ductal; Stomach

Related DT Changes

 Direct regulating

Experiment method

 TF-transporter regulations were collected from ChIP-Seq datasets.

Detailed Description

 Krueppel-like factor 5 (KLF5) can directly bind to the SLC38A1 gene, which in turn affects the expression or function of the drug transporter Sodium-coupled neutral amino acid transporter 1.

        KLF9 

Click to Show/Hide to Show 1 Transcriptional Phenomena      

       Transcriptional Phenomenon1

 Direct binding to SLC38A1 gene [3]

TF Protein Name

 Krueppel-like factor 9 Transcription Factor Info

Related DT Changes

 Direct regulating

Experiment method

 TF-transporter regulations were collected from ChIP-Seq datasets.

Detailed Description

 Krueppel-like factor 9 (KLF9) can directly bind to the SLC38A1 gene, which in turn affects the expression or function of the drug transporter Sodium-coupled neutral amino acid transporter 1.

        MAZ 

Click to Show/Hide to Show 1 Transcriptional Phenomena      

       Transcriptional Phenomenon1

 Direct binding to SLC38A1 gene [3]

TF Protein Name

 Myc-associated zinc finger protein Transcription Factor Info

Tissue

 Blood; Bone marrow; Cervix; Liver; Lung

Related DT Changes

 Direct regulating

Experiment method

 TF-transporter regulations were collected from ChIP-Seq datasets.

Detailed Description

 Myc-associated zinc finger protein (MAZ) can directly bind to the SLC38A1 gene, which in turn affects the expression or function of the drug transporter Sodium-coupled neutral amino acid transporter 1.

        ZNF217 

Click to Show/Hide to Show 1 Transcriptional Phenomena      

       Transcriptional Phenomenon1

 Binding to SLC38A1 gene in breast cancer condition [20]

TF Protein Name

 Zinc finger protein 217 Transcription Factor Info

Studied Phenotype

 .

Related DT Changes

 Direct regulating

Detailed Description

 Zinc finger protein 217 (ZNF217) has been reported to bind to the transcription of SLC38A1 gene in breast cancer condition, which leads to an affected expression of the drug transporter Sodium-coupled neutral amino acid transporter 1.

        ZNF263 

Click to Show/Hide to Show 1 Transcriptional Phenomena      

       Transcriptional Phenomenon1

 Direct binding to SLC38A1 gene [1]

TF Protein Name

 Zinc finger protein 263 Transcription Factor Info

Tissue

 Bone marrow; Kidney

Related DT Changes

 Direct regulating

Experiment method

 TF-transporter regulations were collected from ChIP-Seq datasets.

Detailed Description

 Zinc finger protein 263 (ZNF263) can directly bind to the SLC38A1 gene, which in turn affects the expression or function of the drug transporter Sodium-coupled neutral amino acid transporter 1.

TF Superclass3: Helix-turn-helix domains

      Class3.1: Homeo domain factors

Click to Show/Hide the Full List of 2 TF(s) Regulating This DT

        PBX3 

Click to Show/Hide to Show 1 Transcriptional Phenomena      

       Transcriptional Phenomenon1

 Direct binding to SLC38A1 gene [4]

TF Protein Name

 Pre-B-cell leukemia transcription factor 3 Transcription Factor Info

Tissue

 Blood

Related DT Changes

 Direct regulating

Experiment method

 TF-transporter regulations were collected from ChIP-Seq datasets.

Detailed Description

 Pre-B-cell leukemia transcription factor 3 (PBX3) can directly bind to the SLC38A1 gene, which in turn affects the expression or function of the drug transporter Sodium-coupled neutral amino acid transporter 1.

        POU2F1 

Click to Show/Hide to Show 1 Transcriptional Phenomena      

       Transcriptional Phenomenon1

 Direct binding to SLC38A1 gene [1]

TF Protein Name

 POU domain, class 2, transcription factor 1 Transcription Factor Info

Tissue

 Blood

Related DT Changes

 Direct regulating

Experiment method

 TF-transporter regulations were collected from ChIP-Seq datasets.

Detailed Description

 POU domain, class 2, transcription factor 1 (POU2F1) can directly bind to the SLC38A1 gene, which in turn affects the expression or function of the drug transporter Sodium-coupled neutral amino acid transporter 1.

      Class3.3: Fork head / winged helix factors

Click to Show/Hide the Full List of 7 TF(s) Regulating This DT

        E2F1 

Click to Show/Hide to Show 2 Transcriptional Phenomena      

       Transcriptional Phenomenon1

 Binding to SLC38A1 gene in MCF7 cells [11]

TF Protein Name

 Transcription factor E2F1 Transcription Factor Info

Related DT Changes

 Direct regulating

Detailed Description

 Transcription factor E2F1 (E2F1) has been reported to bind to the transcription of SLC38A1 gene in MCF7 cells, which leads to an affected expression of the drug transporter Sodium-coupled neutral amino acid transporter 1.

       Transcriptional Phenomenon2

 Direct binding to SLC38A1 gene [3]

TF Protein Name

 Transcription factor E2F1 Transcription Factor Info

Tissue

 Mesenchymal

Related DT Changes

 Direct regulating

Experiment method

 TF-transporter regulations were collected from ChIP-Seq datasets.

Detailed Description

 Transcription factor E2F1 (E2F1) can directly bind to the SLC38A1 gene, which in turn affects the expression or function of the drug transporter Sodium-coupled neutral amino acid transporter 1.

        E2F4 

Click to Show/Hide to Show 2 Transcriptional Phenomena      

       Transcriptional Phenomenon1

 Binding to SLC38A1 gene in health condition [21]

TF Protein Name

 Transcription factor E2F4 Transcription Factor Info

Studied Phenotype

 .

Related DT Changes

 Direct regulating

Detailed Description

 Transcription factor E2F4 (E2F4) has been reported to bind to the transcription of SLC38A1 gene in health condition, which leads to an affected expression of the drug transporter Sodium-coupled neutral amino acid transporter 1.

       Transcriptional Phenomenon2

 Binding to SLC38A1 gene in health condition [22]

TF Protein Name

 Transcription factor E2F4 Transcription Factor Info

Studied Phenotype

 .

Related DT Changes

 Direct regulating

Detailed Description

 Transcription factor E2F4 (E2F4) has been reported to bind to the transcription of SLC38A1 gene in health condition, which leads to an affected expression of the drug transporter Sodium-coupled neutral amino acid transporter 1.

        E2F6 

Click to Show/Hide to Show 1 Transcriptional Phenomena      

       Transcriptional Phenomenon1

 Direct binding to SLC38A1 gene [4]

TF Protein Name

 Transcription factor E2F6 Transcription Factor Info

Tissue

 Bone marrow; Cervix; Embryo; Lung

Related DT Changes

 Direct regulating

Experiment method

 TF-transporter regulations were collected from ChIP-Seq datasets.

Detailed Description

 Transcription factor E2F6 (E2F6) can directly bind to the SLC38A1 gene, which in turn affects the expression or function of the drug transporter Sodium-coupled neutral amino acid transporter 1.

        FOXA1 

Click to Show/Hide to Show 1 Transcriptional Phenomena      

       Transcriptional Phenomenon1

 Direct binding to SLC38A1 gene [2]

TF Protein Name

 Hepatocyte nuclear factor 3-alpha Transcription Factor Info

Tissue

 Breast; Embryo; Lung; Prostate

Related DT Changes

 Direct regulating

Experiment method

 TF-transporter regulations were collected from ChIP-Seq datasets.

Detailed Description

 Hepatocyte nuclear factor 3-alpha (FOXA1) can directly bind to the SLC38A1 gene, which in turn affects the expression or function of the drug transporter Sodium-coupled neutral amino acid transporter 1.

        FOXA2 

Click to Show/Hide to Show 1 Transcriptional Phenomena      

       Transcriptional Phenomenon1

 Direct binding to SLC38A1 gene [3]

TF Protein Name

 Hepatocyte nuclear factor 3-beta Transcription Factor Info

Tissue

 Embryo; Endoderm; Liver; Lung; Skin

Related DT Changes

 Direct regulating

Experiment method

 TF-transporter regulations were collected from ChIP-Seq datasets.

Detailed Description

 Hepatocyte nuclear factor 3-beta (FOXA2) can directly bind to the SLC38A1 gene, which in turn affects the expression or function of the drug transporter Sodium-coupled neutral amino acid transporter 1.

        FOXM1 

Click to Show/Hide to Show 2 Transcriptional Phenomena      

       Transcriptional Phenomenon1

 Activation of SLC38A1 gene in breast cancer condition [23]

TF Protein Name

 Forkhead box protein M1 Transcription Factor Info

Studied Phenotype

 .

Related DT Changes

 Up regulating

Detailed Description

 Forkhead box protein M1 (FOXM1) has been reported to activate the transcription of SLC38A1 gene in breast cancer condition, which leads to an increased expression of the drug transporter Sodium-coupled neutral amino acid transporter 1.

       Transcriptional Phenomenon2

 Direct binding to SLC38A1 gene [3]

TF Protein Name

 Forkhead box protein M1 Transcription Factor Info

Tissue

 Blood; Breast

Related DT Changes

 Direct regulating

Experiment method

 TF-transporter regulations were collected from ChIP-Seq datasets.

Detailed Description

 Forkhead box protein M1 (FOXM1) can directly bind to the SLC38A1 gene, which in turn affects the expression or function of the drug transporter Sodium-coupled neutral amino acid transporter 1.

        FOXP1 

Click to Show/Hide to Show 1 Transcriptional Phenomena      

       Transcriptional Phenomenon1

 Direct binding to SLC38A1 gene [4]

TF Protein Name

 Forkhead box protein P1 Transcription Factor Info

Tissue

 Blood; Embryo; Prostate

Related DT Changes

 Direct regulating

Experiment method

 TF-transporter regulations were collected from ChIP-Seq datasets.

Detailed Description

 Forkhead box protein P1 (FOXP1) can directly bind to the SLC38A1 gene, which in turn affects the expression or function of the drug transporter Sodium-coupled neutral amino acid transporter 1.

      Class3.5: Tryptophan cluster factors

Click to Show/Hide the Full List of 10 TF(s) Regulating This DT

        ELK1 

Click to Show/Hide to Show 1 Transcriptional Phenomena      

       Transcriptional Phenomenon1

 Direct binding to SLC38A1 gene [24]

TF Protein Name

 ETS domain-containing protein Elk-1 Transcription Factor Info

Related DT Changes

 Direct regulating

Detailed Description

 ETS domain-containing protein Elk-1 (ELK1) can directly bind to the SLC38A1 gene, which in turn affects the expression or function of the drug transporter Sodium-coupled neutral amino acid transporter 1.

        ELK3 

Click to Show/Hide to Show 1 Transcriptional Phenomena      

       Transcriptional Phenomenon1

 Direct binding to SLC38A1 gene [1]

TF Protein Name

 ETS domain-containing protein Elk-3 Transcription Factor Info

Tissue

 Vein

Related DT Changes

 Direct regulating

Experiment method

 TF-transporter regulations were collected from ChIP-Seq datasets.

Detailed Description

 ETS domain-containing protein Elk-3 (ELK3) can directly bind to the SLC38A1 gene, which in turn affects the expression or function of the drug transporter Sodium-coupled neutral amino acid transporter 1.

        ERG 

Click to Show/Hide to Show 1 Transcriptional Phenomena      

       Transcriptional Phenomenon1

 Binding to SLC38A1 gene in oncogenesis condition [13]

TF Protein Name

 Transcriptional regulator ERG Transcription Factor Info

Studied Phenotype

 .

Related DT Changes

 Direct regulating

Detailed Description

 Transcriptional regulator ERG (ERG) has been reported to bind to the transcription of SLC38A1 gene in oncogenesis condition, which leads to an affected expression of the drug transporter Sodium-coupled neutral amino acid transporter 1.

        ETS1 

Click to Show/Hide to Show 1 Transcriptional Phenomena      

       Transcriptional Phenomenon1

 Direct binding to SLC38A1 gene [1]

TF Protein Name

 Protein C-ets-1 Transcription Factor Info

Tissue

 Blood; Bone; Bone marrow; Kidney; Lung; Prostate; Vein

Related DT Changes

 Direct regulating

Experiment method

 TF-transporter regulations were collected from ChIP-Seq datasets.

Detailed Description

 Protein C-ets-1 (ETS1) can directly bind to the SLC38A1 gene, which in turn affects the expression or function of the drug transporter Sodium-coupled neutral amino acid transporter 1.

        FLI1 

Click to Show/Hide to Show 2 Transcriptional Phenomena      

       Transcriptional Phenomenon1

 Binding to SLC38A1 gene in megakaryocytes condition [25]

TF Protein Name

 Friend leukemia integration 1 transcription factor Transcription Factor Info

Related DT Changes

 Direct regulating

Detailed Description

 Friend leukemia integration 1 transcription factor (FLI1) has been reported to bind to the transcription of SLC38A1 gene in megakaryocytes condition, which leads to an affected expression of the drug transporter Sodium-coupled neutral amino acid transporter 1.

       Transcriptional Phenomenon2

 Direct binding to SLC38A1 gene [2]

TF Protein Name

 Friend leukemia integration 1 transcription factor Transcription Factor Info

Tissue

 Blood; Mesenchymal; Vein

Related DT Changes

 Direct regulating

Experiment method

 TF-transporter regulations were collected from ChIP-Seq datasets.

Detailed Description

 Friend leukemia integration 1 transcription factor (FLI1) can directly bind to the SLC38A1 gene, which in turn affects the expression or function of the drug transporter Sodium-coupled neutral amino acid transporter 1.

        GABPA 

Click to Show/Hide to Show 1 Transcriptional Phenomena      

       Transcriptional Phenomenon1

 Direct binding to SLC38A1 gene [1]

TF Protein Name

 GA-binding protein alpha chain Transcription Factor Info

Tissue

 Bone marrow; Breast; Liver; Lung; Prostate

Related DT Changes

 Direct regulating

Experiment method

 TF-transporter regulations were collected from ChIP-Seq datasets.

Detailed Description

 GA-binding protein alpha chain (GABPA) can directly bind to the SLC38A1 gene, which in turn affects the expression or function of the drug transporter Sodium-coupled neutral amino acid transporter 1.

        IRF1 

Click to Show/Hide to Show 1 Transcriptional Phenomena      

       Transcriptional Phenomenon1

 Direct binding to SLC38A1 gene [4]

TF Protein Name

 Interferon regulatory factor 1 Transcription Factor Info

Tissue

 Blood; Pancreatic ductal

Related DT Changes

 Direct regulating

Experiment method

 TF-transporter regulations were collected from ChIP-Seq datasets.

Detailed Description

 Interferon regulatory factor 1 (IRF1) can directly bind to the SLC38A1 gene, which in turn affects the expression or function of the drug transporter Sodium-coupled neutral amino acid transporter 1.

        IRF4 

Click to Show/Hide to Show 1 Transcriptional Phenomena      

       Transcriptional Phenomenon1

 Direct binding to SLC38A1 gene [2]

TF Protein Name

 Interferon regulatory factor 4 Transcription Factor Info

Tissue

 Blood

Related DT Changes

 Direct regulating

Experiment method

 TF-transporter regulations were collected from ChIP-Seq datasets.

Detailed Description

 Interferon regulatory factor 4 (IRF4) can directly bind to the SLC38A1 gene, which in turn affects the expression or function of the drug transporter Sodium-coupled neutral amino acid transporter 1.

        SPI1 

Click to Show/Hide to Show 1 Transcriptional Phenomena      

       Transcriptional Phenomenon1

 Binding to SLC38A1 gene in HL60 condition [13]

TF Protein Name

 Transcription factor PU.1 Transcription Factor Info

Studied Phenotype

 .

Related DT Changes

 Direct regulating

Detailed Description

 Transcription factor PU.1 (SPI1) has been reported to bind to the transcription of SLC38A1 gene in HL60 condition, which leads to an affected expression of the drug transporter Sodium-coupled neutral amino acid transporter 1.

        SPIB 

Click to Show/Hide to Show 1 Transcriptional Phenomena      

       Transcriptional Phenomenon1

 Direct binding to SLC38A1 gene [2]

TF Protein Name

 Transcription factor Spi-B Transcription Factor Info

Tissue

 Blood; Colon

Related DT Changes

 Direct regulating

Experiment method

 TF-transporter regulations were collected from ChIP-Seq datasets.

Detailed Description

 Transcription factor Spi-B (SPIB) can directly bind to the SLC38A1 gene, which in turn affects the expression or function of the drug transporter Sodium-coupled neutral amino acid transporter 1.

      Class3.7: ARID domain factors

Click to Show/Hide the Full List of 1 TF(s) Regulating This DT

        KDM5B 

Click to Show/Hide to Show 1 Transcriptional Phenomena      

       Transcriptional Phenomenon1

 Direct binding to SLC38A1 gene [3]

TF Protein Name

 Lysine-specific demethylase 5B Transcription Factor Info

Tissue

 Bone marrow; Breast

Related DT Changes

 Direct regulating

Experiment method

 TF-transporter regulations were collected from ChIP-Seq datasets.

Detailed Description

 Lysine-specific demethylase 5B (KDM5B) can directly bind to the SLC38A1 gene, which in turn affects the expression or function of the drug transporter Sodium-coupled neutral amino acid transporter 1.

TF Superclass6: Immunoglobulin fold

      Class6.2: STAT domain factors

Click to Show/Hide the Full List of 2 TF(s) Regulating This DT

        STAT3 

Click to Show/Hide to Show 1 Transcriptional Phenomena      

       Transcriptional Phenomenon1

 Binding to SLC38A1 gene in glioblastoma multiforme condition [26]

TF Protein Name

 Signal transducer and activator of transcription 3 Transcription Factor Info

Affected Drug/Substrate

 Temozolomide

Studied Phenotype

 .

Related DT Changes

 Direct regulating

Detailed Description

 Signal transducer and activator of transcription 3 (STAT3) has been reported to bind to the transcription of SLC38A1 gene in glioblastoma multiforme condition, which leads to an affected expression of the drug transporter Sodium-coupled neutral amino acid transporter 1.

        STAT6 

Click to Show/Hide to Show 1 Transcriptional Phenomena      

       Transcriptional Phenomenon1

 Activation of SLC38A1 gene in immune-mediated diseases condition [27]

TF Protein Name

 Signal transducer and activator of transcription 6 Transcription Factor Info

Studied Phenotype

 .

Related DT Changes

 Up regulating

Detailed Description

 Signal transducer and activator of transcription 6 (STAT6) has been reported to activate the transcription of SLC38A1 gene in immune-mediated diseases condition, which leads to an increased expression of the drug transporter Sodium-coupled neutral amino acid transporter 1.

      Class6.3: p53 domain factors

Click to Show/Hide the Full List of 1 TF(s) Regulating This DT

        TP63 

Click to Show/Hide to Show 1 Transcriptional Phenomena      

       Transcriptional Phenomenon1

 Binding to SLC38A1 gene in epithelial to mesenchymal transition condition [28]

TF Protein Name

 Tumor protein 63 Transcription Factor Info

Studied Phenotype

 .

Related DT Changes

 Direct regulating

Detailed Description

 Tumor protein 63 (TP63) has been reported to bind to the transcription of SLC38A1 gene in epithelial to mesenchymal transition condition, which leads to an affected expression of the drug transporter Sodium-coupled neutral amino acid transporter 1.

      Class6.4: Runt domain factors

Click to Show/Hide the Full List of 3 TF(s) Regulating This DT

        RUNX1 

Click to Show/Hide to Show 2 Transcriptional Phenomena      

       Transcriptional Phenomenon1

 Binding to SLC38A1 gene in health condition [21]

TF Protein Name

 Runt-related transcription factor 1 Transcription Factor Info

Studied Phenotype

 .

Related DT Changes

 Direct regulating

Detailed Description

 Runt-related transcription factor 1 (RUNX1) has been reported to bind to the transcription of SLC38A1 gene in health condition, which leads to an affected expression of the drug transporter Sodium-coupled neutral amino acid transporter 1.

       Transcriptional Phenomenon2

 Binding to SLC38A1 gene in megakaryocytes condition [25]

TF Protein Name

 Runt-related transcription factor 1 Transcription Factor Info

Related DT Changes

 Direct regulating

Detailed Description

 Runt-related transcription factor 1 (RUNX1) has been reported to bind to the transcription of SLC38A1 gene in megakaryocytes condition, which leads to an affected expression of the drug transporter Sodium-coupled neutral amino acid transporter 1.

        RUNX2 

Click to Show/Hide to Show 1 Transcriptional Phenomena      

       Transcriptional Phenomenon1

 Activation of SLC38A1 gene in prostate cancer condition [29]

TF Protein Name

 Runt-related transcription factor 2 Transcription Factor Info

Studied Phenotype

 .

Related DT Changes

 Up regulating

Detailed Description

 Runt-related transcription factor 2 (RUNX2) has been reported to activate the transcription of SLC38A1 gene in prostate cancer condition, which leads to an increased expression of the drug transporter Sodium-coupled neutral amino acid transporter 1.

        RUNX3 

Click to Show/Hide to Show 1 Transcriptional Phenomena      

       Transcriptional Phenomenon1

 Direct binding to SLC38A1 gene [4]

TF Protein Name

 Runt-related transcription factor 3 Transcription Factor Info

Tissue

 Blood

Related DT Changes

 Direct regulating

Experiment method

 TF-transporter regulations were collected from ChIP-Seq datasets.

Detailed Description

 Runt-related transcription factor 3 (RUNX3) can directly bind to the SLC38A1 gene, which in turn affects the expression or function of the drug transporter Sodium-coupled neutral amino acid transporter 1.

      Class6.7: Grainyhead domain factors

Click to Show/Hide the Full List of 1 TF(s) Regulating This DT

        GRHL3 

Click to Show/Hide to Show 1 Transcriptional Phenomena      

       Transcriptional Phenomenon1

 Direct binding to SLC38A1 gene [3]

TF Protein Name

 Grainyhead-like protein 3 homolog Transcription Factor Info

Tissue

 Skin

Related DT Changes

 Direct regulating

Experiment method

 TF-transporter regulations were collected from ChIP-Seq datasets.

Detailed Description

 Grainyhead-like protein 3 homolog (GRHL3) can directly bind to the SLC38A1 gene, which in turn affects the expression or function of the drug transporter Sodium-coupled neutral amino acid transporter 1.

TF Superclass7: beta-Hairpin exposed by an alpha/beta-scaffold

      Class7.1: SMAD/NF-1 DNA-binding domain factors

Click to Show/Hide the Full List of 1 TF(s) Regulating This DT

        NFIC 

Click to Show/Hide to Show 1 Transcriptional Phenomena      

       Transcriptional Phenomenon1

 Direct binding to SLC38A1 gene [2]

TF Protein Name

 Nuclear factor 1 C-type Transcription Factor Info

Tissue

 Blood; Brain; Uterus

Related DT Changes

 Direct regulating

Experiment method

 TF-transporter regulations were collected from ChIP-Seq datasets.

Detailed Description

 Nuclear factor 1 C-type (NFIC) can directly bind to the SLC38A1 gene, which in turn affects the expression or function of the drug transporter Sodium-coupled neutral amino acid transporter 1.

TF Superclass10: Yet undefined DNA-binding domains

      Class10.1: Other factors

Click to Show/Hide the Full List of 1 TF(s) Regulating This DT

        GTF2B 

Click to Show/Hide to Show 1 Transcriptional Phenomena      

       Transcriptional Phenomenon1

 Direct binding to SLC38A1 gene [1]

TF Protein Name

 Transcription initiation factor IIB Transcription Factor Info

Tissue

 Cervix; Lung

Related DT Changes

 Direct regulating

Experiment method

 TF-transporter regulations were collected from ChIP-Seq datasets.

Detailed Description

 Transcription initiation factor IIB (GTF2B) can directly bind to the SLC38A1 gene, which in turn affects the expression or function of the drug transporter Sodium-coupled neutral amino acid transporter 1.
References
1 The Encyclopedia of DNA elements (ENCODE): data portal update. Nucleic Acids Res. 2018 Jan 4;46(D1):D794-D801
2 hTFtarget: A Comprehensive Database for Regulations of Human Transcription Factors and Their Targets. Genomics Proteomics Bioinformatics. 2020 Apr;18(2):120-214. (ID:ENSG00000111371)
3 NCBI GEO: archive for functional genomics data sets--update. Nucleic Acids Res. 2013 Jan;41(D1):D991-5.
4 Closure of the NCBI SRA and implications for the long-term future of genomics data storage. Genome Biol. 2011;12(3):402.
5 Upregulation of the glutamine transporter through transactivation mediated by cAMP/protein kinase A signals toward exacerbation of vulnerability to oxidative stress in rat neocortical astrocytes. J Cell Physiol. 2007 Aug;212(2):375-85.
6 Promoter characterization and role of CRE in the basal transcription of the rat SNAT2 gene. Am J Physiol Endocrinol Metab. 2011 Jun;300(6):E1092-102.
7 High-resolution genome-wide mapping of AHR and ARNT binding sites by ChIP-Seq. Toxicol Sci. 2012 Dec;130(2):349-61.
8 Hypoxic Stress Upregulates the Expression of Slc38a1 in Brown Adipocytes via Hypoxia-Inducible Factor-1alpha. Pharmacology. 2018;101(1-2):64-71.
9 miR-373-3p Regulates the Proliferative and Migratory Properties of Human HTR8 Cells via SLC38A1 Modulation. Dis Markers. 2022 Jun 28;2022:6582357.
10 Gene regulation and epigenetic remodeling in murine embryonic stem cells by c-Myc. PLoS One. 2009;4(11):e7839.
11 A computational genomics approach to identify cis-regulatory modules from chromatin immunoprecipitation microarray data--a case study using E2F1. Genome Res. 2006;16(12):1585-95.
12 Identification of primary gene targets of TFAP2C in hormone responsive breast carcinoma cells. Genes Chromosomes Cancer. 2010;49(10):948-62.
13 Genome-wide analysis of ETS-family DNA-binding in vitro and in vivo. EMBO J. 2010;29(13):2147-60.
14 Mapping of HNF4alpha target genes in intestinal epithelial cells. BMC Gastroenterol. 2009;9:68.
15 Molecular interactions between HNF4a, FOXA2 and GABP identified at regulatory DNA elements through ChIP-sequencing. Nucleic Acids Res. 2009;37(22):7498-508.
16 Genomewide analyses define different modes of transcriptional regulation by peroxisome proliferator-activated receptor. PLoS One. 2011;6(1):e16344.
17 Regulation of expression and role of peroxisome proliferator-activated receptors (PPARs) in luminal epithelial and stromal cells of the porcine endometrium. Theriogenology. 2019 Mar 15;127:88-101.
18 Regulatory crosstalk between lineage-survival oncogenes KLF5, GATA4 and GATA6 cooperatively promotes gastric cancer development. Gut. 2015;64(5):707-19.
19 The transcriptional regulator BCL6 participates in the secondary gene regulatory response to vitamin D. Biochim Biophys Acta. 2015;1849(3):300-8.
20 Global analysis of ZNF217 chromatin occupancy in the breast cancer cell genome reveals an association with ERalpha. BMC Genomics. 2014;15(1):520.
21 Genome-wide analyses reveal properties of redundant and specific promoter occupancy within the ETS gene family. Genes Dev. 2007;21(15):1882-94.
22 Wide-ranging functions of E2F4 in transcriptional activation and repression revealed by genome-wide analysis. Nucleic Acids Res. 2011;39(9):3558-73.
23 FOXM1 cistrome predicts breast cancer metastatic outcome better than FOXM1 expression levels or tumor proliferation index. Breast Cancer Res Treat. 2015;154(1):23-32.
24 Elucidation of the ELK1 target gene network reveals a role in the coordinate regulation of core components of the gene regulation machinery. Genome Res. 2009;19(11):1963-73.
25 Genome-wide analysis of simultaneous GATA1/2, RUNX1, FLI1, and SCL binding in megakaryocytes identifies hematopoietic regulators. Dev Cell. 2011;20(5):597-609.
26 Unique genome-wide map of TCF4 and STAT3 targets using ChIP-seq reveals their association with new molecular subtypes of glioblastoma. Neuro Oncol. 2013;15(3):279-89.
27 Genome-wide profiling of interleukin-4 and STAT6 transcription factor regulation of human Th2 cell programming. Immunity. 2010;32(6):852-62.
28 p63 attenuates epithelial to mesenchymal potential in an experimental prostate cell model. PLoS One. 2013;8(5):e62547.
29 Genome-wide Runx2 occupancy in prostate cancer cells suggests a role in regulating secretion. Nucleic Acids Res. 2012;40(8):3538-47.

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