| General Information of DT | |||||
|---|---|---|---|---|---|
| DT ID | DTD0546 | ||||
| Gene Name | KCNK9 | ||||
| Protein Name | Potassium channel subfamily K member 9 | ||||
| Gene ID | |||||
| UniProt ID | |||||
| TCDB ID | |||||
| 3D Structure |
Modelled DT Structure Method:homology modeling Template PDB:6RV2_A Identity:75% Minimized Score:-646.7 kcal/mol Detail: Structure Info |
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| Synonyms | Acid-sensitive potassium channel protein TASK-3; TWIK-related acid-sensitive K(+) channel 3; Two pore potassium channel KT3.2; Two pore K(+) channel KT3.2 | ||||
| DT Family | Voltage-gated Ion Channel (VIC) Superfamily ; | ||||
| Tissue Specificity | Mainly found in the cerebellum. Also found in adrenal gland, kidney and lung. | ||||
| Function | This transporter is pH-dependent, voltage-insensitive, background potassium channel protein. | ||||
| Variability Data of This Drug Transporter (DT) | |||||
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Regulatory Variability Data of This DT (VARIDT 4.0) |
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(α) Tissue Distribution Level of Potassium channel subfamily K member 9 |
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(β) Cell Distribution Level of Potassium channel subfamily K member 9 |
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(γ) Organelle Distribution Level of Potassium channel subfamily K member 9 |
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Regulatory Variability Data of This DT |
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(β) Post-translational Modification of Potassium channel subfamily K member 9 |
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(δ) Epigenetic Regulation of Potassium channel subfamily K member 9 |
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(ε) Exogenous Modulation of Potassium channel subfamily K member 9 |
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Structural Variability Data of This DT |
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(α) Mutation-induced Structural Variation |
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(β) Inter-species Structural Differences |
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General Variability Data of This DT |
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(α) Genetic Polymorphisms of Potassium channel subfamily K member 9 |
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(β) Disease-specific Protein Abundances of Potassium channel subfamily K member 9 |
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(γ) Species- and Tissue-specific DT Abundances |
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