Modelled DT Structure
Method: multi-sequence alignment based machine learning
Detail: Structure Info
Drug Transporter (DT) Information
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| General Information of DT | |||||
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| DT ID | DTD0494 | ||||
| Gene Name | SLC9A9 | ||||
| Protein Name | Sodium/hydrogen exchanger 9 | ||||
| Gene ID | |||||
| UniProt ID | |||||
| TCDB ID | |||||
| 3D Structure |
Modelled DT Structure Method: multi-sequence alignment based machine learning Detail: Structure Info |
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| Synonyms | AUTS16; NHE-9; NHE9; Na(+)/H(+) exchanger 9; Nbla00118; SLC9A9; Solute carrier family 9 member 9 | ||||
| DT Family | Monovalent Cation:Proton Antiporter-1 (CPA1) family ; | ||||
| Tissue Specificity | Ubiquitously expressed in all tissues tested.Expressed at highest levels in heart and skeletal muscle, followedby placenta, kidney, and liver. Expressed in the brain, in themedulla and spinal cord. | ||||
| Function | This transporter mediates proton electrically neutral exchange of sodium (+) through the membrane. | ||||
| Endogenous Substrate(s) | Na+; H+ | ||||
| Variability Data of This Drug Transporter (DT) | |||||
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Regulatory Variability Data of This DT (VARIDT 4.0) |
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(α) Tissue Distribution Level of Sodium/hydrogen exchanger 9 |
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(β) Cell Distribution Level of Sodium/hydrogen exchanger 9 |
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(γ) Organelle Distribution Level of Sodium/hydrogen exchanger 9 |
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Regulatory Variability Data of This DT |
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(β) Post-translational Modification of Sodium/hydrogen exchanger 9 |
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(γ) Transcriptional Regulation of Sodium/hydrogen exchanger 9 |
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(δ) Epigenetic Regulation of Sodium/hydrogen exchanger 9 |
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(ε) Exogenous Modulation of Sodium/hydrogen exchanger 9 |
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General Variability Data of This DT |
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(α) Genetic Polymorphisms of Sodium/hydrogen exchanger 9 |
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(β) Disease-specific Protein Abundances of Sodium/hydrogen exchanger 9 |
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(γ) Species- and Tissue-specific DT Abundances |
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If you find any error in data or bug in web service, please kindly report it to Dr. Li and Dr. Fu.