Drug Transporter (DT) Information

General Information of DT
DT ID DTD0193
Gene Name SLC25A31
Protein Name Adenine nucleotide translocator 4
Gene ID
83447
UniProt ID
Q9H0C2
TCDB ID
2.A.29.1.8
3D Structure

Modelled DT Structure

Method:homology modeling

Template PDB:1OKC_A

Identity:73.038%

Minimized Score:-728.43 kcal/mol

Detail: Structure Info

Synonyms ADP,ATP carrier protein 4; ADP/ATP translocase 4; Solute carrier family 25 member 31; Sperm flagellar energy carrier protein; SLC25A31; AAC4; ANT4; SFEC; ANT 4
DT Family Mitochondrial Carrier (MC) Family ;
Tissue Specificity Expressed in brain, liver, sperm and testis.
Function This transporter can catalyzes the exchange of cytoplasmic ADP with mitochondrial ATP across the mitochondrial inner membrane.
Endogenous Substrate(s) ADP; ATP
Variability Data of This Drug Transporter (DT)

Regulatory Variability Data of This DT (VARIDT 4.0)

(α) Tissue Distribution Level of Adenine nucleotide translocator 4
Tissue Distribution Level (TD)

(β) Cell Distribution Level of Adenine nucleotide translocator 4
Cell Distribution Level (CD)

(γ) Organelle Distribution Level of Adenine nucleotide translocator 4
Organelle Distribution Level (Subc)

Regulatory Variability Data of This DT

(β) Post-translational Modification of Adenine nucleotide translocator 4
Post-translational Modification (PTM)

(γ) Transcriptional Regulation of Adenine nucleotide translocator 4
Transcriptional Regulation (TSR)

(δ) Epigenetic Regulation of Adenine nucleotide translocator 4
Epigenetic Regulation (EGR)

(ε) Exogenous Modulation of Adenine nucleotide translocator 4
Exogenous Modulation (EGM)

Structural Variability Data of This DT

(β) Inter-species Structural Differences
Inter-species Structural Differences (ISD)

General Variability Data of This DT

(α) Genetic Polymorphisms of Adenine nucleotide translocator 4
Genetic Polymorphisms of This DT (GPD)

(β) Disease-specific Protein Abundances of Adenine nucleotide translocator 4
Disease-specific Protein Abundances of This DT (DPAD)

(γ) Species- and Tissue-specific DT Abundances
Species/Tissue-specific Protein Abundances of This DT (S/TPAD)

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