| General Information of DT | |||||
|---|---|---|---|---|---|
| DT ID | DTD0543 | ||||
| Gene Name | KCNN1 | ||||
| Protein Name | Small conductance calcium-activated potassium channel protein 1 | ||||
| Gene ID | |||||
| UniProt ID | |||||
| TCDB ID | |||||
| 3D Structure |
Modelled DT Structure Method:homology modeling Template PDB:6CNM_A Identity:42.129% Minimized Score:-992.683 kcal/mol Detail: Structure Info |
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| Synonyms | SK1; SKCa 1; SKCa1; KCa2.1; KCNN1; SK | ||||
| DT Family | Voltage-gated Ion Channel (VIC) Superfamily ; | ||||
| Function | This transporter is a voltage-independent potassium channel activated by intracellular calcium. | ||||
| Variability Data of This Drug Transporter (DT) | |||||
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Regulatory Variability Data of This DT (VARIDT 4.0) |
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(α) Tissue Distribution Level of Small conductance calcium-activated potassium channel protein 1 |
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(β) Cell Distribution Level of Small conductance calcium-activated potassium channel protein 1 |
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(γ) Organelle Distribution Level of Small conductance calcium-activated potassium channel protein 1 |
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Regulatory Variability Data of This DT |
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(β) Post-translational Modification of Small conductance calcium-activated potassium channel protein 1 |
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(γ) Transcriptional Regulation of Small conductance calcium-activated potassium channel protein 1 |
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(δ) Epigenetic Regulation of Small conductance calcium-activated potassium channel protein 1 |
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(ε) Exogenous Modulation of Small conductance calcium-activated potassium channel protein 1 |
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Structural Variability Data of This DT |
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(β) Inter-species Structural Differences |
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General Variability Data of This DT |
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(α) Genetic Polymorphisms of Small conductance calcium-activated potassium channel protein 1 |
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(β) Disease-specific Protein Abundances of Small conductance calcium-activated potassium channel protein 1 |
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(γ) Species- and Tissue-specific DT Abundances |
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