Detail Information of Transcriptional Regulations
General Information of Drug Transporter (DT) | |||||
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DT ID | DTD0390 Transporter Info | ||||
Gene Name | SLC50A1 | ||||
Transporter Name | Sugar transporter SWEET1 | ||||
Gene ID | |||||
UniProt ID | |||||
Transcriptional Regulation of This DT (TSR) | ||||||
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Class1.1: Basic leucine zipper factors |
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ATF3 |
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Transcriptional Phenomenon1 |
Repression of SLC50A1 gene in glioblastoma multiforme condition | [1] | ||||
TF Protein Name |
Cyclic AMP-dependent transcription factor ATF-3 | Transcription Factor Info | ||||
Studied Phenotype |
. | |||||
Related DT Changes |
Down regulating | |||||
Detailed Description |
Cyclic AMP-dependent transcription factor ATF-3 (ATF3) has been reported to repress the transcription of SLC50A1 gene in glioblastoma multiforme condition, which leads to a decreased expression of the drug transporter Sugar transporter SWEET1. | |||||
Transcriptional Phenomenon2 |
Direct binding to SLC50A1 gene | [2] | ||||
TF Protein Name |
Cyclic AMP-dependent transcription factor ATF-3 | Transcription Factor Info | ||||
Tissue |
Colon | |||||
Related DT Changes |
Direct regulating | |||||
Experiment method |
TF-transporter regulations were collected from ChIP-Seq datasets. | |||||
Detailed Description |
Cyclic AMP-dependent transcription factor ATF-3 (ATF3) can directly bind to the SLC50A1 gene, which in turn affects the expression or function of the drug transporter Sugar transporter SWEET1. | |||||
BACH1 |
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Transcriptional Phenomenon1 |
Direct binding to SLC50A1 gene | [3] | ||||
TF Protein Name |
Transcription regulator protein BACH1 | Transcription Factor Info | ||||
Tissue |
Embryo | |||||
Related DT Changes |
Direct regulating | |||||
Experiment method |
TF-transporter regulations were collected from ChIP-Seq datasets. | |||||
Detailed Description |
Transcription regulator protein BACH1 (BACH1) can directly bind to the SLC50A1 gene, which in turn affects the expression or function of the drug transporter Sugar transporter SWEET1. | |||||
CREB1 |
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Transcriptional Phenomenon1 |
Direct binding to SLC50A1 gene | [4] | ||||
TF Protein Name |
Cyclic AMP-responsive element-binding protein 1 | Transcription Factor Info | ||||
Tissue |
Liver | |||||
Related DT Changes |
Direct regulating | |||||
Experiment method |
TF-transporter regulations were collected from ChIP-Seq datasets. | |||||
Detailed Description |
Cyclic AMP-responsive element-binding protein 1 (CREB1) can directly bind to the SLC50A1 gene, which in turn affects the expression or function of the drug transporter Sugar transporter SWEET1. | |||||
FOS |
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Transcriptional Phenomenon1 |
Direct binding to SLC50A1 gene | [5] | ||||
TF Protein Name |
Protein c-Fos | Transcription Factor Info | ||||
Tissue |
Bone marrow; Breast; Vein | |||||
Related DT Changes |
Direct regulating | |||||
Experiment method |
TF-transporter regulations were collected from ChIP-Seq datasets. | |||||
Detailed Description |
Protein c-Fos (FOS) can directly bind to the SLC50A1 gene, which in turn affects the expression or function of the drug transporter Sugar transporter SWEET1. | |||||
FOSL2 |
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Transcriptional Phenomenon1 |
Direct binding to SLC50A1 gene | [2] | ||||
TF Protein Name |
Fos-related antigen 2 | Transcription Factor Info | ||||
Tissue |
Brain; Breast; Liver; Lung | |||||
Related DT Changes |
Direct regulating | |||||
Experiment method |
TF-transporter regulations were collected from ChIP-Seq datasets. | |||||
Detailed Description |
Fos-related antigen 2 (FOSL2) can directly bind to the SLC50A1 gene, which in turn affects the expression or function of the drug transporter Sugar transporter SWEET1. | |||||
JUNB |
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Transcriptional Phenomenon1 |
Direct binding to SLC50A1 gene | [4] | ||||
TF Protein Name |
Transcription factor JunB | Transcription Factor Info | ||||
Tissue |
Aorta | |||||
Related DT Changes |
Direct regulating | |||||
Experiment method |
TF-transporter regulations were collected from ChIP-Seq datasets. | |||||
Detailed Description |
Transcription factor JunB (JUNB) can directly bind to the SLC50A1 gene, which in turn affects the expression or function of the drug transporter Sugar transporter SWEET1. | |||||
JUND |
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Transcriptional Phenomenon1 |
Direct binding to SLC50A1 gene | [5] | ||||
TF Protein Name |
Transcription factor JunD | Transcription Factor Info | ||||
Tissue |
Bone marrow; Breast; Cervix; Colon; Coronary artery; Embryo; Liver; Lung; Prostate | |||||
Related DT Changes |
Direct regulating | |||||
Experiment method |
TF-transporter regulations were collected from ChIP-Seq datasets. | |||||
Detailed Description |
Transcription factor JunD (JUND) can directly bind to the SLC50A1 gene, which in turn affects the expression or function of the drug transporter Sugar transporter SWEET1. | |||||
NFE2 |
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Transcriptional Phenomenon1 |
Direct binding to SLC50A1 gene | [4] | ||||
TF Protein Name |
Transcription factor NF-E2 45 kDa subunit | Transcription Factor Info | ||||
Tissue |
Liver | |||||
Related DT Changes |
Direct regulating | |||||
Experiment method |
TF-transporter regulations were collected from ChIP-Seq datasets. | |||||
Detailed Description |
Transcription factor NF-E2 45 kDa subunit (NFE2) can directly bind to the SLC50A1 gene, which in turn affects the expression or function of the drug transporter Sugar transporter SWEET1. | |||||
Class1.2: Basic helix-loop-helix factors |
Click to Show/Hide the Full List of 12 TF(s) Regulating This DT |
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ARNT |
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Transcriptional Phenomenon1 |
Direct binding to SLC50A1 gene | [5] | ||||
TF Protein Name |
Aryl hydrocarbon receptor nuclear translocator | Transcription Factor Info | ||||
Tissue |
Breast | |||||
Related DT Changes |
Direct regulating | |||||
Experiment method |
TF-transporter regulations were collected from ChIP-Seq datasets. | |||||
Detailed Description |
Aryl hydrocarbon receptor nuclear translocator (ARNT) can directly bind to the SLC50A1 gene, which in turn affects the expression or function of the drug transporter Sugar transporter SWEET1. | |||||
BHLHE40 |
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Transcriptional Phenomenon1 |
Direct binding to SLC50A1 gene | [3] | ||||
TF Protein Name |
Class E basic helix-loop-helix protein 40 | Transcription Factor Info | ||||
Tissue |
Bone marrow; Liver | |||||
Related DT Changes |
Direct regulating | |||||
Experiment method |
TF-transporter regulations were collected from ChIP-Seq datasets. | |||||
Detailed Description |
Class E basic helix-loop-helix protein 40 (BHLHE40) can directly bind to the SLC50A1 gene, which in turn affects the expression or function of the drug transporter Sugar transporter SWEET1. | |||||
HEY1 |
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Transcriptional Phenomenon1 |
Direct binding to SLC50A1 gene | [3] | ||||
TF Protein Name |
Hairy/enhancer-of-split related with YRPW motif protein 1 | Transcription Factor Info | ||||
Tissue |
Bone marrow | |||||
Related DT Changes |
Direct regulating | |||||
Experiment method |
TF-transporter regulations were collected from ChIP-Seq datasets. | |||||
Detailed Description |
Hairy/enhancer-of-split related with YRPW motif protein 1 (HEY1) can directly bind to the SLC50A1 gene, which in turn affects the expression or function of the drug transporter Sugar transporter SWEET1. | |||||
MAX |
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Transcriptional Phenomenon1 |
Direct binding to SLC50A1 gene | [2] | ||||
TF Protein Name |
Protein max | Transcription Factor Info | ||||
Tissue |
Bone marrow; Brain; Breast; Cervix; Colon; Liver | |||||
Related DT Changes |
Direct regulating | |||||
Experiment method |
TF-transporter regulations were collected from ChIP-Seq datasets. | |||||
Detailed Description |
Protein max (MAX) can directly bind to the SLC50A1 gene, which in turn affects the expression or function of the drug transporter Sugar transporter SWEET1. | |||||
MXI1 |
Click to Show/Hide to Show 1 Transcriptional Phenomena |
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Transcriptional Phenomenon1 |
Direct binding to SLC50A1 gene | [3] | ||||
TF Protein Name |
Max-interacting protein 1 | Transcription Factor Info | ||||
Tissue |
Bone marrow; Cervix; Liver | |||||
Related DT Changes |
Direct regulating | |||||
Experiment method |
TF-transporter regulations were collected from ChIP-Seq datasets. | |||||
Detailed Description |
Max-interacting protein 1 (MXI1) can directly bind to the SLC50A1 gene, which in turn affects the expression or function of the drug transporter Sugar transporter SWEET1. | |||||
MYCN |
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Transcriptional Phenomenon1 |
Activation of SLC50A1 gene in neuroblastoma condition | [6] | ||||
TF Protein Name |
N-myc proto-oncogene protein | Transcription Factor Info | ||||
Studied Phenotype |
. | |||||
Related DT Changes |
Up regulating | |||||
Detailed Description |
N-myc proto-oncogene protein (MYCN) has been reported to activate the transcription of SLC50A1 gene in neuroblastoma condition, which leads to an increased expression of the drug transporter Sugar transporter SWEET1. | |||||
MYOD1 |
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Transcriptional Phenomenon1 |
Direct binding to SLC50A1 gene | [4] | ||||
TF Protein Name |
Myoblast determination protein 1 | Transcription Factor Info | ||||
Tissue |
Myotube | |||||
Related DT Changes |
Direct regulating | |||||
Experiment method |
TF-transporter regulations were collected from ChIP-Seq datasets. | |||||
Detailed Description |
Myoblast determination protein 1 (MYOD1) can directly bind to the SLC50A1 gene, which in turn affects the expression or function of the drug transporter Sugar transporter SWEET1. | |||||
TCF12 |
Click to Show/Hide to Show 1 Transcriptional Phenomena |
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Transcriptional Phenomenon1 |
Direct binding to SLC50A1 gene | [5] | ||||
TF Protein Name |
Transcription factor 12 | Transcription Factor Info | ||||
Tissue |
Blood; Breast; Embryo; Liver; Lung; Uterus | |||||
Related DT Changes |
Direct regulating | |||||
Experiment method |
TF-transporter regulations were collected from ChIP-Seq datasets. | |||||
Detailed Description |
Transcription factor 12 (TCF12) can directly bind to the SLC50A1 gene, which in turn affects the expression or function of the drug transporter Sugar transporter SWEET1. | |||||
TCF21 |
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Transcriptional Phenomenon1 |
Direct binding to SLC50A1 gene | [5] | ||||
TF Protein Name |
Transcription factor 21 | Transcription Factor Info | ||||
Tissue |
Coronary artery | |||||
Related DT Changes |
Direct regulating | |||||
Experiment method |
TF-transporter regulations were collected from ChIP-Seq datasets. | |||||
Detailed Description |
Transcription factor 21 (TCF21) can directly bind to the SLC50A1 gene, which in turn affects the expression or function of the drug transporter Sugar transporter SWEET1. | |||||
TCF3 |
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Transcriptional Phenomenon1 |
Direct binding to SLC50A1 gene | [2] | ||||
TF Protein Name |
Transcription factor E2-alpha | Transcription Factor Info | ||||
Tissue |
Blood | |||||
Related DT Changes |
Direct regulating | |||||
Experiment method |
TF-transporter regulations were collected from ChIP-Seq datasets. | |||||
Detailed Description |
Transcription factor E2-alpha (TCF3) can directly bind to the SLC50A1 gene, which in turn affects the expression or function of the drug transporter Sugar transporter SWEET1. | |||||
TFAP4 |
Click to Show/Hide to Show 1 Transcriptional Phenomena |
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Transcriptional Phenomenon1 |
Direct binding to SLC50A1 gene | [3] | ||||
TF Protein Name |
Transcription factor AP-4 | Transcription Factor Info | ||||
Tissue |
Blood; Prostate | |||||
Related DT Changes |
Direct regulating | |||||
Experiment method |
TF-transporter regulations were collected from ChIP-Seq datasets. | |||||
Detailed Description |
Transcription factor AP-4 (TFAP4) can directly bind to the SLC50A1 gene, which in turn affects the expression or function of the drug transporter Sugar transporter SWEET1. | |||||
USF1 |
Click to Show/Hide to Show 1 Transcriptional Phenomena |
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Transcriptional Phenomenon1 |
Direct binding to SLC50A1 gene | [2] | ||||
TF Protein Name |
Upstream stimulatory factor 1 | Transcription Factor Info | ||||
Tissue |
Liver | |||||
Related DT Changes |
Direct regulating | |||||
Experiment method |
TF-transporter regulations were collected from ChIP-Seq datasets. | |||||
Detailed Description |
Upstream stimulatory factor 1 (USF1) can directly bind to the SLC50A1 gene, which in turn affects the expression or function of the drug transporter Sugar transporter SWEET1. | |||||
Class1.3: Basic helix-span-helix factors |
Click to Show/Hide the Full List of 2 TF(s) Regulating This DT |
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TFAP2A |
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Transcriptional Phenomenon1 |
Direct binding to SLC50A1 gene | [3] | ||||
TF Protein Name |
Transcription factor AP-2-alpha | Transcription Factor Info | ||||
Tissue |
Breast; Cervix | |||||
Related DT Changes |
Direct regulating | |||||
Experiment method |
TF-transporter regulations were collected from ChIP-Seq datasets. | |||||
Detailed Description |
Transcription factor AP-2-alpha (TFAP2A) can directly bind to the SLC50A1 gene, which in turn affects the expression or function of the drug transporter Sugar transporter SWEET1. | |||||
TFAP2C |
Click to Show/Hide to Show 1 Transcriptional Phenomena |
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Transcriptional Phenomenon1 |
Direct binding to SLC50A1 gene | [4] | ||||
TF Protein Name |
Transcription factor AP-2 gamma | Transcription Factor Info | ||||
Tissue |
Breast; Cervix; Skin | |||||
Related DT Changes |
Direct regulating | |||||
Experiment method |
TF-transporter regulations were collected from ChIP-Seq datasets. | |||||
Detailed Description |
Transcription factor AP-2 gamma (TFAP2C) can directly bind to the SLC50A1 gene, which in turn affects the expression or function of the drug transporter Sugar transporter SWEET1. | |||||
Class2.1: Nuclear receptors with C4 zinc fingers |
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AR |
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Transcriptional Phenomenon1 |
Direct binding to SLC50A1 gene | [2] | ||||
TF Protein Name |
Androgen receptor | Transcription Factor Info | ||||
Tissue |
Breast; Cervix; Kidney; Prostate | |||||
Related DT Changes |
Direct regulating | |||||
Experiment method |
TF-transporter regulations were collected from ChIP-Seq datasets. | |||||
Detailed Description |
Androgen receptor (AR) can directly bind to the SLC50A1 gene, which in turn affects the expression or function of the drug transporter Sugar transporter SWEET1. | |||||
ESR1 |
Click to Show/Hide to Show 1 Transcriptional Phenomena |
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Transcriptional Phenomenon1 |
Direct binding to SLC50A1 gene | [3] | ||||
TF Protein Name |
Estrogen receptor | Transcription Factor Info | ||||
Tissue |
Breast | |||||
Related DT Changes |
Direct regulating | |||||
Experiment method |
TF-transporter regulations were collected from ChIP-Seq datasets. | |||||
Detailed Description |
Estrogen receptor (ESR1) can directly bind to the SLC50A1 gene, which in turn affects the expression or function of the drug transporter Sugar transporter SWEET1. | |||||
HNF4A |
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Transcriptional Phenomenon1 |
Direct binding to SLC50A1 gene | [2] | ||||
TF Protein Name |
Hepatocyte nuclear factor 4-alpha | Transcription Factor Info | ||||
Tissue |
Colon; Intestine; Liver | |||||
Related DT Changes |
Direct regulating | |||||
Experiment method |
TF-transporter regulations were collected from ChIP-Seq datasets. | |||||
Detailed Description |
Hepatocyte nuclear factor 4-alpha (HNF4A) can directly bind to the SLC50A1 gene, which in turn affects the expression or function of the drug transporter Sugar transporter SWEET1. | |||||
HNF4G |
Click to Show/Hide to Show 1 Transcriptional Phenomena |
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Transcriptional Phenomenon1 |
Direct binding to SLC50A1 gene | [4] | ||||
TF Protein Name |
Hepatocyte nuclear factor 4-gamma | Transcription Factor Info | ||||
Tissue |
Liver | |||||
Related DT Changes |
Direct regulating | |||||
Experiment method |
TF-transporter regulations were collected from ChIP-Seq datasets. | |||||
Detailed Description |
Hepatocyte nuclear factor 4-gamma (HNF4G) can directly bind to the SLC50A1 gene, which in turn affects the expression or function of the drug transporter Sugar transporter SWEET1. | |||||
NR2C2 |
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Transcriptional Phenomenon1 |
Direct binding to SLC50A1 gene | [4] | ||||
TF Protein Name |
Nuclear receptor subfamily 2 group C member 2 | Transcription Factor Info | ||||
Tissue |
Cervix; Liver | |||||
Related DT Changes |
Direct regulating | |||||
Experiment method |
TF-transporter regulations were collected from ChIP-Seq datasets. | |||||
Detailed Description |
Nuclear receptor subfamily 2 group C member 2 (NR2C2) can directly bind to the SLC50A1 gene, which in turn affects the expression or function of the drug transporter Sugar transporter SWEET1. | |||||
NR2F2 |
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Transcriptional Phenomenon1 |
Direct binding to SLC50A1 gene | [5] | ||||
TF Protein Name |
COUP transcription factor 2 | Transcription Factor Info | ||||
Tissue |
Bone marrow; Breast; Liver | |||||
Related DT Changes |
Direct regulating | |||||
Experiment method |
TF-transporter regulations were collected from ChIP-Seq datasets. | |||||
Detailed Description |
COUP transcription factor 2 (NR2F2) can directly bind to the SLC50A1 gene, which in turn affects the expression or function of the drug transporter Sugar transporter SWEET1. | |||||
RXRA |
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Transcriptional Phenomenon1 |
Direct binding to SLC50A1 gene | [2] | ||||
TF Protein Name |
Retinoic acid receptor RXR-alpha | Transcription Factor Info | ||||
Tissue |
Colon; Liver | |||||
Related DT Changes |
Direct regulating | |||||
Experiment method |
TF-transporter regulations were collected from ChIP-Seq datasets. | |||||
Detailed Description |
Retinoic acid receptor RXR-alpha (RXRA) can directly bind to the SLC50A1 gene, which in turn affects the expression or function of the drug transporter Sugar transporter SWEET1. | |||||
Class2.2: Other C4 zinc finger-type factors |
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GATA1 |
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Transcriptional Phenomenon1 |
Direct binding to SLC50A1 gene | [4] | ||||
TF Protein Name |
Erythroid transcription factor | Transcription Factor Info | ||||
Tissue |
Blood; Bone marrow | |||||
Related DT Changes |
Direct regulating | |||||
Experiment method |
TF-transporter regulations were collected from ChIP-Seq datasets. | |||||
Detailed Description |
Erythroid transcription factor (GATA1) can directly bind to the SLC50A1 gene, which in turn affects the expression or function of the drug transporter Sugar transporter SWEET1. | |||||
GATA2 |
Click to Show/Hide to Show 1 Transcriptional Phenomena |
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Transcriptional Phenomenon1 |
Activation of SLC50A1 gene in health condition | [7] | ||||
TF Protein Name |
Endothelial transcription factor GATA-2 | Transcription Factor Info | ||||
Studied Phenotype |
. | |||||
Related DT Changes |
Up regulating | |||||
Detailed Description |
Endothelial transcription factor GATA-2 (GATA2) has been reported to activate the transcription of SLC50A1 gene in health condition, which leads to an increased expression of the drug transporter Sugar transporter SWEET1. | |||||
GATA3 |
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Transcriptional Phenomenon1 |
Direct binding to SLC50A1 gene | [5] | ||||
TF Protein Name |
Trans-acting T-cell-specific transcription factor GATA-3 | Transcription Factor Info | ||||
Tissue |
Blood; Breast; Lung | |||||
Related DT Changes |
Direct regulating | |||||
Experiment method |
TF-transporter regulations were collected from ChIP-Seq datasets. | |||||
Detailed Description |
Trans-acting T-cell-specific transcription factor GATA-3 (GATA3) can directly bind to the SLC50A1 gene, which in turn affects the expression or function of the drug transporter Sugar transporter SWEET1. | |||||
Class2.3: C2H2 zinc finger factors |
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BCL6 |
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Transcriptional Phenomenon1 |
Direct binding to SLC50A1 gene | [3] | ||||
TF Protein Name |
B-cell lymphoma 6 protein | Transcription Factor Info | ||||
Tissue |
Blood; Tonsil | |||||
Related DT Changes |
Direct regulating | |||||
Experiment method |
TF-transporter regulations were collected from ChIP-Seq datasets. | |||||
Detailed Description |
B-cell lymphoma 6 protein (BCL6) can directly bind to the SLC50A1 gene, which in turn affects the expression or function of the drug transporter Sugar transporter SWEET1. | |||||
CTCF |
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Transcriptional Phenomenon1 |
Direct binding to SLC50A1 gene | [5] | ||||
TF Protein Name |
Transcriptional repressor CTCF | Transcription Factor Info | ||||
Tissue |
Striated muscle | |||||
Related DT Changes |
Direct regulating | |||||
Experiment method |
TF-transporter regulations were collected from ChIP-Seq datasets. | |||||
Detailed Description |
Transcriptional repressor CTCF (CTCF) can directly bind to the SLC50A1 gene, which in turn affects the expression or function of the drug transporter Sugar transporter SWEET1. | |||||
EGR1 |
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Transcriptional Phenomenon1 |
Binding to SLC50A1 gene in erythroleukemia condition | [8] | ||||
TF Protein Name |
Early growth response protein 1 | Transcription Factor Info | ||||
Studied Phenotype |
. | |||||
Related DT Changes |
Direct regulating | |||||
Detailed Description |
Early growth response protein 1 (EGR1) has been reported to bind to the transcription of SLC50A1 gene in erythroleukemia condition, which leads to an affected expression of the drug transporter Sugar transporter SWEET1. | |||||
Transcriptional Phenomenon2 |
Direct binding to SLC50A1 gene | [2] | ||||
TF Protein Name |
Early growth response protein 1 | Transcription Factor Info | ||||
Tissue |
Blood; Bone marrow; Breast; Colon; Embryo; Uterus | |||||
Related DT Changes |
Direct regulating | |||||
Experiment method |
TF-transporter regulations were collected from ChIP-Seq datasets. | |||||
Detailed Description |
Early growth response protein 1 (EGR1) can directly bind to the SLC50A1 gene, which in turn affects the expression or function of the drug transporter Sugar transporter SWEET1. | |||||
KLF1 |
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Transcriptional Phenomenon1 |
Direct binding to SLC50A1 gene | [3] | ||||
TF Protein Name |
Krueppel-like factor 1 | Transcription Factor Info | ||||
Tissue |
Blood | |||||
Related DT Changes |
Direct regulating | |||||
Experiment method |
TF-transporter regulations were collected from ChIP-Seq datasets. | |||||
Detailed Description |
Krueppel-like factor 1 (KLF1) can directly bind to the SLC50A1 gene, which in turn affects the expression or function of the drug transporter Sugar transporter SWEET1. | |||||
KLF4 |
Click to Show/Hide to Show 1 Transcriptional Phenomena |
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Transcriptional Phenomenon1 |
Direct binding to SLC50A1 gene | [4] | ||||
TF Protein Name |
Krueppel-like factor 4 | Transcription Factor Info | ||||
Tissue |
Foreskin; Pancreatic ductal; Skin | |||||
Related DT Changes |
Direct regulating | |||||
Experiment method |
TF-transporter regulations were collected from ChIP-Seq datasets. | |||||
Detailed Description |
Krueppel-like factor 4 (KLF4) can directly bind to the SLC50A1 gene, which in turn affects the expression or function of the drug transporter Sugar transporter SWEET1. | |||||
KLF5 |
Click to Show/Hide to Show 2 Transcriptional Phenomena |
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Transcriptional Phenomenon1 |
Activation of SLC50A1 gene in gastric cancer condition | [9] | ||||
TF Protein Name |
Krueppel-like factor 5 | Transcription Factor Info | ||||
Studied Phenotype |
. | |||||
Related DT Changes |
Up regulating | |||||
Detailed Description |
Krueppel-like factor 5 (KLF5) has been reported to activate the transcription of SLC50A1 gene in gastric cancer condition, which leads to an increased expression of the drug transporter Sugar transporter SWEET1. | |||||
Transcriptional Phenomenon2 |
Direct binding to SLC50A1 gene | [5] | ||||
TF Protein Name |
Krueppel-like factor 5 | Transcription Factor Info | ||||
Tissue |
Colon; Pancreatic ductal; Stomach | |||||
Related DT Changes |
Direct regulating | |||||
Experiment method |
TF-transporter regulations were collected from ChIP-Seq datasets. | |||||
Detailed Description |
Krueppel-like factor 5 (KLF5) can directly bind to the SLC50A1 gene, which in turn affects the expression or function of the drug transporter Sugar transporter SWEET1. | |||||
KLF9 |
Click to Show/Hide to Show 1 Transcriptional Phenomena |
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Transcriptional Phenomenon1 |
Direct binding to SLC50A1 gene | [2] | ||||
TF Protein Name |
Krueppel-like factor 9 | Transcription Factor Info | ||||
Related DT Changes |
Direct regulating | |||||
Experiment method |
TF-transporter regulations were collected from ChIP-Seq datasets. | |||||
Detailed Description |
Krueppel-like factor 9 (KLF9) can directly bind to the SLC50A1 gene, which in turn affects the expression or function of the drug transporter Sugar transporter SWEET1. | |||||
MAZ |
Click to Show/Hide to Show 1 Transcriptional Phenomena |
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Transcriptional Phenomenon1 |
Direct binding to SLC50A1 gene | [5] | ||||
TF Protein Name |
Myc-associated zinc finger protein | Transcription Factor Info | ||||
Tissue |
Blood; Bone marrow; Cervix; Liver; Lung | |||||
Related DT Changes |
Direct regulating | |||||
Experiment method |
TF-transporter regulations were collected from ChIP-Seq datasets. | |||||
Detailed Description |
Myc-associated zinc finger protein (MAZ) can directly bind to the SLC50A1 gene, which in turn affects the expression or function of the drug transporter Sugar transporter SWEET1. | |||||
MECOM |
Click to Show/Hide to Show 1 Transcriptional Phenomena |
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Transcriptional Phenomenon1 |
Direct binding to SLC50A1 gene | [3] | ||||
TF Protein Name |
Histone-lysine N-methyltransferase MECOM | Transcription Factor Info | ||||
Tissue |
Colon | |||||
Related DT Changes |
Direct regulating | |||||
Experiment method |
TF-transporter regulations were collected from ChIP-Seq datasets. | |||||
Detailed Description |
Histone-lysine N-methyltransferase MECOM (MECOM) can directly bind to the SLC50A1 gene, which in turn affects the expression or function of the drug transporter Sugar transporter SWEET1. | |||||
SP1 |
Click to Show/Hide to Show 1 Transcriptional Phenomena |
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Transcriptional Phenomenon1 |
Direct binding to SLC50A1 gene | [3] | ||||
TF Protein Name |
Transcription factor Sp1 | Transcription Factor Info | ||||
Tissue |
Blood; Colon; Embryo; Liver; Lung | |||||
Related DT Changes |
Direct regulating | |||||
Experiment method |
TF-transporter regulations were collected from ChIP-Seq datasets. | |||||
Detailed Description |
Transcription factor Sp1 (SP1) can directly bind to the SLC50A1 gene, which in turn affects the expression or function of the drug transporter Sugar transporter SWEET1. | |||||
SP4 |
Click to Show/Hide to Show 1 Transcriptional Phenomena |
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Transcriptional Phenomenon1 |
Direct binding to SLC50A1 gene | [4] | ||||
TF Protein Name |
Transcription factor Sp4 | Transcription Factor Info | ||||
Tissue |
Embryo | |||||
Related DT Changes |
Direct regulating | |||||
Experiment method |
TF-transporter regulations were collected from ChIP-Seq datasets. | |||||
Detailed Description |
Transcription factor Sp4 (SP4) can directly bind to the SLC50A1 gene, which in turn affects the expression or function of the drug transporter Sugar transporter SWEET1. | |||||
VEZF1 |
Click to Show/Hide to Show 1 Transcriptional Phenomena |
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Transcriptional Phenomenon1 |
Direct binding to SLC50A1 gene | [2] | ||||
TF Protein Name |
Vascular endothelial zinc finger 1 | Transcription Factor Info | ||||
Tissue |
Colon | |||||
Related DT Changes |
Direct regulating | |||||
Experiment method |
TF-transporter regulations were collected from ChIP-Seq datasets. | |||||
Detailed Description |
Vascular endothelial zinc finger 1 (VEZF1) can directly bind to the SLC50A1 gene, which in turn affects the expression or function of the drug transporter Sugar transporter SWEET1. | |||||
ZBTB7A |
Click to Show/Hide to Show 1 Transcriptional Phenomena |
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Transcriptional Phenomenon1 |
Direct binding to SLC50A1 gene | [5] | ||||
TF Protein Name |
Zinc finger and BTB domain-containing protein 7A | Transcription Factor Info | ||||
Tissue |
Bone marrow; Liver; Uterus | |||||
Related DT Changes |
Direct regulating | |||||
Experiment method |
TF-transporter regulations were collected from ChIP-Seq datasets. | |||||
Detailed Description |
Zinc finger and BTB domain-containing protein 7A (ZBTB7A) can directly bind to the SLC50A1 gene, which in turn affects the expression or function of the drug transporter Sugar transporter SWEET1. | |||||
ZNF263 |
Click to Show/Hide to Show 1 Transcriptional Phenomena |
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Transcriptional Phenomenon1 |
Direct binding to SLC50A1 gene | [3] | ||||
TF Protein Name |
Zinc finger protein 263 | Transcription Factor Info | ||||
Tissue |
Bone marrow; Kidney | |||||
Related DT Changes |
Direct regulating | |||||
Experiment method |
TF-transporter regulations were collected from ChIP-Seq datasets. | |||||
Detailed Description |
Zinc finger protein 263 (ZNF263) can directly bind to the SLC50A1 gene, which in turn affects the expression or function of the drug transporter Sugar transporter SWEET1. | |||||
Class3.1: Homeo domain factors |
Click to Show/Hide the Full List of 1 TF(s) Regulating This DT |
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NKX2-1 |
Click to Show/Hide to Show 1 Transcriptional Phenomena |
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Transcriptional Phenomenon1 |
Direct binding to SLC50A1 gene | [5] | ||||
TF Protein Name |
Homeobox protein Nkx-2.1 | Transcription Factor Info | ||||
Tissue |
Lung | |||||
Related DT Changes |
Direct regulating | |||||
Experiment method |
TF-transporter regulations were collected from ChIP-Seq datasets. | |||||
Detailed Description |
Homeobox protein Nkx-2.1 (NKX2-1) can directly bind to the SLC50A1 gene, which in turn affects the expression or function of the drug transporter Sugar transporter SWEET1. | |||||
Class3.3: Fork head / winged helix factors |
Click to Show/Hide the Full List of 6 TF(s) Regulating This DT |
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E2F1 |
Click to Show/Hide to Show 1 Transcriptional Phenomena |
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Transcriptional Phenomenon1 |
Direct binding to SLC50A1 gene | [5] | ||||
TF Protein Name |
Transcription factor E2F1 | Transcription Factor Info | ||||
Tissue |
Mesenchymal | |||||
Related DT Changes |
Direct regulating | |||||
Experiment method |
TF-transporter regulations were collected from ChIP-Seq datasets. | |||||
Detailed Description |
Transcription factor E2F1 (E2F1) can directly bind to the SLC50A1 gene, which in turn affects the expression or function of the drug transporter Sugar transporter SWEET1. | |||||
E2F4 |
Click to Show/Hide to Show 1 Transcriptional Phenomena |
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Transcriptional Phenomenon1 |
Binding to SLC50A1 gene in health condition | [10] | ||||
TF Protein Name |
Transcription factor E2F4 | Transcription Factor Info | ||||
Studied Phenotype |
. | |||||
Related DT Changes |
Direct regulating | |||||
Detailed Description |
Transcription factor E2F4 (E2F4) has been reported to bind to the transcription of SLC50A1 gene in health condition, which leads to an affected expression of the drug transporter Sugar transporter SWEET1. | |||||
E2F6 |
Click to Show/Hide to Show 1 Transcriptional Phenomena |
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Transcriptional Phenomenon1 |
Direct binding to SLC50A1 gene | [2] | ||||
TF Protein Name |
Transcription factor E2F6 | Transcription Factor Info | ||||
Tissue |
Bone marrow; Embryo; Lung | |||||
Related DT Changes |
Direct regulating | |||||
Experiment method |
TF-transporter regulations were collected from ChIP-Seq datasets. | |||||
Detailed Description |
Transcription factor E2F6 (E2F6) can directly bind to the SLC50A1 gene, which in turn affects the expression or function of the drug transporter Sugar transporter SWEET1. | |||||
FOXA1 |
Click to Show/Hide to Show 1 Transcriptional Phenomena |
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Transcriptional Phenomenon1 |
Direct binding to SLC50A1 gene | [5] | ||||
TF Protein Name |
Hepatocyte nuclear factor 3-alpha | Transcription Factor Info | ||||
Tissue |
Breast; Embryo; Liver; Lung; Pancreatic ductal; Prostate | |||||
Related DT Changes |
Direct regulating | |||||
Experiment method |
TF-transporter regulations were collected from ChIP-Seq datasets. | |||||
Detailed Description |
Hepatocyte nuclear factor 3-alpha (FOXA1) can directly bind to the SLC50A1 gene, which in turn affects the expression or function of the drug transporter Sugar transporter SWEET1. | |||||
FOXA2 |
Click to Show/Hide to Show 1 Transcriptional Phenomena |
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Transcriptional Phenomenon1 |
Direct binding to SLC50A1 gene | [2] | ||||
TF Protein Name |
Hepatocyte nuclear factor 3-beta | Transcription Factor Info | ||||
Tissue |
Colon | |||||
Related DT Changes |
Direct regulating | |||||
Experiment method |
TF-transporter regulations were collected from ChIP-Seq datasets. | |||||
Detailed Description |
Hepatocyte nuclear factor 3-beta (FOXA2) can directly bind to the SLC50A1 gene, which in turn affects the expression or function of the drug transporter Sugar transporter SWEET1. | |||||
FOXP1 |
Click to Show/Hide to Show 1 Transcriptional Phenomena |
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Transcriptional Phenomenon1 |
Direct binding to SLC50A1 gene | [2] | ||||
TF Protein Name |
Forkhead box protein P1 | Transcription Factor Info | ||||
Tissue |
Colon; Embryo | |||||
Related DT Changes |
Direct regulating | |||||
Experiment method |
TF-transporter regulations were collected from ChIP-Seq datasets. | |||||
Detailed Description |
Forkhead box protein P1 (FOXP1) can directly bind to the SLC50A1 gene, which in turn affects the expression or function of the drug transporter Sugar transporter SWEET1. | |||||
Class3.5: Tryptophan cluster factors |
Click to Show/Hide the Full List of 9 TF(s) Regulating This DT |
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ELK1 |
Click to Show/Hide to Show 1 Transcriptional Phenomena |
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Transcriptional Phenomenon1 |
Binding to SLC50A1 gene in . condition | [11] | ||||
TF Protein Name |
ETS domain-containing protein Elk-1 | Transcription Factor Info | ||||
Related DT Changes |
Direct regulating | |||||
Detailed Description |
ETS domain-containing protein Elk-1 (ELK1) has been reported to bind to the SLC50A1 gene in . condition, which leads to a affected expression of the drug transporter Sugar transporter SWEET1. | |||||
ELK3 |
Click to Show/Hide to Show 1 Transcriptional Phenomena |
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Transcriptional Phenomenon1 |
Binding to SLC50A1 gene in hypoxia condition | [12] | ||||
TF Protein Name |
ETS domain-containing protein Elk-3 | Transcription Factor Info | ||||
Studied Phenotype |
. | |||||
Related DT Changes |
Direct regulating | |||||
Detailed Description |
ETS domain-containing protein Elk-3 (ELK3) has been reported to bind to the transcription of SLC50A1 gene in hypoxia condition, which leads to an affected expression of the drug transporter Sugar transporter SWEET1. | |||||
ERG |
Click to Show/Hide to Show 1 Transcriptional Phenomena |
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Transcriptional Phenomenon1 |
Direct binding to SLC50A1 gene | [3] | ||||
TF Protein Name |
Transcriptional regulator ERG | Transcription Factor Info | ||||
Tissue |
Aorta | |||||
Related DT Changes |
Direct regulating | |||||
Experiment method |
TF-transporter regulations were collected from ChIP-Seq datasets. | |||||
Detailed Description |
Transcriptional regulator ERG (ERG) can directly bind to the SLC50A1 gene, which in turn affects the expression or function of the drug transporter Sugar transporter SWEET1. | |||||
ETS1 |
Click to Show/Hide to Show 1 Transcriptional Phenomena |
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Transcriptional Phenomenon1 |
Direct binding to SLC50A1 gene | [4] | ||||
TF Protein Name |
Protein C-ets-1 | Transcription Factor Info | ||||
Tissue |
Blood; Bone; Bone marrow; Kidney; Lung; Prostate; Vein | |||||
Related DT Changes |
Direct regulating | |||||
Experiment method |
TF-transporter regulations were collected from ChIP-Seq datasets. | |||||
Detailed Description |
Protein C-ets-1 (ETS1) can directly bind to the SLC50A1 gene, which in turn affects the expression or function of the drug transporter Sugar transporter SWEET1. | |||||
FLI1 |
Click to Show/Hide to Show 2 Transcriptional Phenomena |
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Transcriptional Phenomenon1 |
Binding to SLC50A1 gene in megakaryocytes condition | [13] | ||||
TF Protein Name |
Friend leukemia integration 1 transcription factor | Transcription Factor Info | ||||
Related DT Changes |
Direct regulating | |||||
Detailed Description |
Friend leukemia integration 1 transcription factor (FLI1) has been reported to bind to the transcription of SLC50A1 gene in megakaryocytes condition, which leads to an affected expression of the drug transporter Sugar transporter SWEET1. | |||||
Transcriptional Phenomenon2 |
Direct binding to SLC50A1 gene | [5] | ||||
TF Protein Name |
Friend leukemia integration 1 transcription factor | Transcription Factor Info | ||||
Tissue |
Blood; Mesenchymal; Umbilical cord blood; Vein | |||||
Related DT Changes |
Direct regulating | |||||
Experiment method |
TF-transporter regulations were collected from ChIP-Seq datasets. | |||||
Detailed Description |
Friend leukemia integration 1 transcription factor (FLI1) can directly bind to the SLC50A1 gene, which in turn affects the expression or function of the drug transporter Sugar transporter SWEET1. | |||||
GABPA |
Click to Show/Hide to Show 1 Transcriptional Phenomena |
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Transcriptional Phenomenon1 |
Direct binding to SLC50A1 gene | [3] | ||||
TF Protein Name |
GA-binding protein alpha chain | Transcription Factor Info | ||||
Tissue |
Blood; Bone; Bone marrow; Brain; Breast; Cervix; Embryo; Liver; Lung; Mesenchymal; Prostate | |||||
Related DT Changes |
Direct regulating | |||||
Experiment method |
TF-transporter regulations were collected from ChIP-Seq datasets. | |||||
Detailed Description |
GA-binding protein alpha chain (GABPA) can directly bind to the SLC50A1 gene, which in turn affects the expression or function of the drug transporter Sugar transporter SWEET1. | |||||
IRF1 |
Click to Show/Hide to Show 1 Transcriptional Phenomena |
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Transcriptional Phenomenon1 |
Direct binding to SLC50A1 gene | [3] | ||||
TF Protein Name |
Interferon regulatory factor 1 | Transcription Factor Info | ||||
Tissue |
Bone marrow; Pancreatic ductal | |||||
Related DT Changes |
Direct regulating | |||||
Experiment method |
TF-transporter regulations were collected from ChIP-Seq datasets. | |||||
Detailed Description |
Interferon regulatory factor 1 (IRF1) can directly bind to the SLC50A1 gene, which in turn affects the expression or function of the drug transporter Sugar transporter SWEET1. | |||||
MYB |
Click to Show/Hide to Show 1 Transcriptional Phenomena |
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Transcriptional Phenomenon1 |
Direct binding to SLC50A1 gene | [4] | ||||
TF Protein Name |
Transcriptional activator Myb | Transcription Factor Info | ||||
Tissue |
Blood | |||||
Related DT Changes |
Direct regulating | |||||
Experiment method |
TF-transporter regulations were collected from ChIP-Seq datasets. | |||||
Detailed Description |
Transcriptional activator Myb (MYB) can directly bind to the SLC50A1 gene, which in turn affects the expression or function of the drug transporter Sugar transporter SWEET1. | |||||
SPI1 |
Click to Show/Hide to Show 2 Transcriptional Phenomena |
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Transcriptional Phenomenon1 |
Binding to SLC50A1 gene in acute myeloid leukemia condition | [14] | ||||
TF Protein Name |
Transcription factor PU.1 | Transcription Factor Info | ||||
Studied Phenotype |
. | |||||
Related DT Changes |
Direct regulating | |||||
Detailed Description |
Transcription factor PU.1 (SPI1) has been reported to bind to the transcription of SLC50A1 gene in acute myeloid leukemia condition, which leads to an affected expression of the drug transporter Sugar transporter SWEET1. | |||||
Transcriptional Phenomenon2 |
Direct binding to SLC50A1 gene | [2] | ||||
TF Protein Name |
Transcription factor PU.1 | Transcription Factor Info | ||||
Tissue |
Adrenal gland; Blood; Bone marrow; Brain; Breast; Embryo; Foreskin; Heart; Intestine; Kidney; Lung; Muscle; Penis; Placenta; Renal cortex; Renal pelvis; Skin; Spinal cord; Stomach; Testes; Umbilical cord blood | |||||
Related DT Changes |
Direct regulating | |||||
Experiment method |
TF-transporter regulations were collected from ChIP-Seq datasets. | |||||
Detailed Description |
Transcription factor PU.1 (SPI1) can directly bind to the SLC50A1 gene, which in turn affects the expression or function of the drug transporter Sugar transporter SWEET1. | |||||
Class3.7: ARID domain factors |
Click to Show/Hide the Full List of 1 TF(s) Regulating This DT |
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KDM5B |
Click to Show/Hide to Show 1 Transcriptional Phenomena |
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Transcriptional Phenomenon1 |
Direct binding to SLC50A1 gene | [4] | ||||
TF Protein Name |
Lysine-specific demethylase 5B | Transcription Factor Info | ||||
Tissue |
Bone marrow; Breast | |||||
Related DT Changes |
Direct regulating | |||||
Experiment method |
TF-transporter regulations were collected from ChIP-Seq datasets. | |||||
Detailed Description |
Lysine-specific demethylase 5B (KDM5B) can directly bind to the SLC50A1 gene, which in turn affects the expression or function of the drug transporter Sugar transporter SWEET1. | |||||
Class4.2: Heteromeric CCAAT-binding factors |
Click to Show/Hide the Full List of 1 TF(s) Regulating This DT |
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NFYA |
Click to Show/Hide to Show 1 Transcriptional Phenomena |
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Transcriptional Phenomenon1 |
Direct binding to SLC50A1 gene | [2] | ||||
TF Protein Name |
Nuclear transcription factor Y subunit alpha | Transcription Factor Info | ||||
Tissue |
Bone marrow | |||||
Related DT Changes |
Direct regulating | |||||
Experiment method |
TF-transporter regulations were collected from ChIP-Seq datasets. | |||||
Detailed Description |
Nuclear transcription factor Y subunit alpha (NFYA) can directly bind to the SLC50A1 gene, which in turn affects the expression or function of the drug transporter Sugar transporter SWEET1. | |||||
Class5.1: MADS box factors |
Click to Show/Hide the Full List of 1 TF(s) Regulating This DT |
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SRF |
Click to Show/Hide to Show 1 Transcriptional Phenomena |
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Transcriptional Phenomenon1 |
Direct binding to SLC50A1 gene | [2] | ||||
TF Protein Name |
Serum response factor | Transcription Factor Info | ||||
Tissue |
Embryo; Uterus | |||||
Related DT Changes |
Direct regulating | |||||
Experiment method |
TF-transporter regulations were collected from ChIP-Seq datasets. | |||||
Detailed Description |
Serum response factor (SRF) can directly bind to the SLC50A1 gene, which in turn affects the expression or function of the drug transporter Sugar transporter SWEET1. | |||||
Class6.1: Rel homology region factors |
Click to Show/Hide the Full List of 1 TF(s) Regulating This DT |
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EBF1 |
Click to Show/Hide to Show 1 Transcriptional Phenomena |
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Transcriptional Phenomenon1 |
Direct binding to SLC50A1 gene | [4] | ||||
TF Protein Name |
Transcription factor COE1 | Transcription Factor Info | ||||
Tissue |
Blood | |||||
Related DT Changes |
Direct regulating | |||||
Experiment method |
TF-transporter regulations were collected from ChIP-Seq datasets. | |||||
Detailed Description |
Transcription factor COE1 (EBF1) can directly bind to the SLC50A1 gene, which in turn affects the expression or function of the drug transporter Sugar transporter SWEET1. | |||||
Class6.2: STAT domain factors |
Click to Show/Hide the Full List of 1 TF(s) Regulating This DT |
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STAT1 |
Click to Show/Hide to Show 1 Transcriptional Phenomena |
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Transcriptional Phenomenon1 |
Direct binding to SLC50A1 gene | [3] | ||||
TF Protein Name |
Signal transducer and activator of transcription 1-alpha/beta | Transcription Factor Info | ||||
Tissue |
Blood; Cervix | |||||
Related DT Changes |
Direct regulating | |||||
Experiment method |
TF-transporter regulations were collected from ChIP-Seq datasets. | |||||
Detailed Description |
Signal transducer and activator of transcription 1-alpha/beta (STAT1) can directly bind to the SLC50A1 gene, which in turn affects the expression or function of the drug transporter Sugar transporter SWEET1. | |||||
Class6.3: p53 domain factors |
Click to Show/Hide the Full List of 1 TF(s) Regulating This DT |
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TP63 |
Click to Show/Hide to Show 1 Transcriptional Phenomena |
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Transcriptional Phenomenon1 |
Binding to SLC50A1 gene in health condition | [15] | ||||
TF Protein Name |
Tumor protein 63 | Transcription Factor Info | ||||
Studied Phenotype |
. | |||||
Related DT Changes |
Direct regulating | |||||
Detailed Description |
Tumor protein 63 (TP63) has been reported to bind to the transcription of SLC50A1 gene in health condition, which leads to an affected expression of the drug transporter Sugar transporter SWEET1. | |||||
Class6.4: Runt domain factors |
Click to Show/Hide the Full List of 1 TF(s) Regulating This DT |
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RUNX1 |
Click to Show/Hide to Show 1 Transcriptional Phenomena |
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Transcriptional Phenomenon1 |
Binding to SLC50A1 gene in megakaryocytes condition | [13] | ||||
TF Protein Name |
Runt-related transcription factor 1 | Transcription Factor Info | ||||
Related DT Changes |
Direct regulating | |||||
Detailed Description |
Runt-related transcription factor 1 (RUNX1) has been reported to bind to the transcription of SLC50A1 gene in megakaryocytes condition, which leads to an affected expression of the drug transporter Sugar transporter SWEET1. | |||||
Class6.7: Grainyhead domain factors |
Click to Show/Hide the Full List of 1 TF(s) Regulating This DT |
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GRHL2 |
Click to Show/Hide to Show 1 Transcriptional Phenomena |
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Transcriptional Phenomenon1 |
Direct binding to SLC50A1 gene | [5] | ||||
TF Protein Name |
Grainyhead-like protein 2 homolog | Transcription Factor Info | ||||
Tissue |
Breast; Bronchus; Ovary | |||||
Related DT Changes |
Direct regulating | |||||
Experiment method |
TF-transporter regulations were collected from ChIP-Seq datasets. | |||||
Detailed Description |
Grainyhead-like protein 2 homolog (GRHL2) can directly bind to the SLC50A1 gene, which in turn affects the expression or function of the drug transporter Sugar transporter SWEET1. | |||||
TF Superclass7: beta-Hairpin exposed by an alpha/beta-scaffold |
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Class7.1: SMAD/NF-1 DNA-binding domain factors |
Click to Show/Hide the Full List of 2 TF(s) Regulating This DT |
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NFIC |
Click to Show/Hide to Show 1 Transcriptional Phenomena |
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Transcriptional Phenomenon1 |
Direct binding to SLC50A1 gene | [4] | ||||
TF Protein Name |
Nuclear factor 1 C-type | Transcription Factor Info | ||||
Tissue |
Liver | |||||
Related DT Changes |
Direct regulating | |||||
Experiment method |
TF-transporter regulations were collected from ChIP-Seq datasets. | |||||
Detailed Description |
Nuclear factor 1 C-type (NFIC) can directly bind to the SLC50A1 gene, which in turn affects the expression or function of the drug transporter Sugar transporter SWEET1. | |||||
SMAD3 |
Click to Show/Hide to Show 1 Transcriptional Phenomena |
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Transcriptional Phenomenon1 |
Binding to SLC50A1 gene in health condition | [16] | ||||
TF Protein Name |
Mothers against decapentaplegic homolog 3 | Transcription Factor Info | ||||
Studied Phenotype |
. | |||||
Related DT Changes |
Direct regulating | |||||
Detailed Description |
Mothers against decapentaplegic homolog 3 (SMAD3) has been reported to bind to the transcription of SLC50A1 gene in health condition, which leads to an affected expression of the drug transporter Sugar transporter SWEET1. | |||||
Class10.1: Other factors |
Click to Show/Hide the Full List of 2 TF(s) Regulating This DT |
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MBD3 |
Click to Show/Hide to Show 1 Transcriptional Phenomena |
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Transcriptional Phenomenon1 |
Direct binding to SLC50A1 gene | [3] | ||||
TF Protein Name |
Methyl-CpG-binding domain protein 3 | Transcription Factor Info | ||||
Tissue |
Breast | |||||
Related DT Changes |
Direct regulating | |||||
Experiment method |
TF-transporter regulations were collected from ChIP-Seq datasets. | |||||
Detailed Description |
Methyl-CpG-binding domain protein 3 (MBD3) can directly bind to the SLC50A1 gene, which in turn affects the expression or function of the drug transporter Sugar transporter SWEET1. | |||||
REPIN1 |
Click to Show/Hide to Show 1 Transcriptional Phenomena |
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Transcriptional Phenomenon1 |
Direct binding to SLC50A1 gene | [4] | ||||
TF Protein Name |
Replication initiator 1 | Transcription Factor Info | ||||
Tissue |
Colon | |||||
Related DT Changes |
Direct regulating | |||||
Experiment method |
TF-transporter regulations were collected from ChIP-Seq datasets. | |||||
Detailed Description |
Replication initiator 1 (REPIN1) can directly bind to the SLC50A1 gene, which in turn affects the expression or function of the drug transporter Sugar transporter SWEET1. | |||||
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