General Information of Drug Transporter (DT)
DT ID DTD0390 Transporter Info
Gene Name SLC50A1
Transporter Name Sugar transporter SWEET1
Gene ID
55974
UniProt ID
Q9BRV3

Transcriptional Regulation of This DT (TSR)

TF Superclass1: Basic domains

      Class1.1: Basic leucine zipper factors

Click to Show/Hide the Full List of 8 TF(s) Regulating This DT

        ATF3 

Click to Show/Hide to Show 2 Transcriptional Phenomena      

       Transcriptional Phenomenon1

Repression of SLC50A1 gene in glioblastoma multiforme condition [1]

TF Protein Name

Cyclic AMP-dependent transcription factor ATF-3 Transcription Factor Info

Studied Phenotype

.

Related DT Changes

Down regulating

Detailed Description

Cyclic AMP-dependent transcription factor ATF-3 (ATF3) has been reported to repress the transcription of SLC50A1 gene in glioblastoma multiforme condition, which leads to a decreased expression of the drug transporter Sugar transporter SWEET1.

       Transcriptional Phenomenon2

Direct binding to SLC50A1 gene [2]

TF Protein Name

Cyclic AMP-dependent transcription factor ATF-3 Transcription Factor Info

Tissue

Colon

Related DT Changes

Direct regulating

Experiment method

TF-transporter regulations were collected from ChIP-Seq datasets.

Detailed Description

Cyclic AMP-dependent transcription factor ATF-3 (ATF3) can directly bind to the SLC50A1 gene, which in turn affects the expression or function of the drug transporter Sugar transporter SWEET1.

        BACH1 

Click to Show/Hide to Show 1 Transcriptional Phenomena      

       Transcriptional Phenomenon1

Direct binding to SLC50A1 gene [3]

TF Protein Name

Transcription regulator protein BACH1 Transcription Factor Info

Tissue

Embryo

Related DT Changes

Direct regulating

Experiment method

TF-transporter regulations were collected from ChIP-Seq datasets.

Detailed Description

Transcription regulator protein BACH1 (BACH1) can directly bind to the SLC50A1 gene, which in turn affects the expression or function of the drug transporter Sugar transporter SWEET1.

        CREB1 

Click to Show/Hide to Show 1 Transcriptional Phenomena      

       Transcriptional Phenomenon1

Direct binding to SLC50A1 gene [4]

TF Protein Name

Cyclic AMP-responsive element-binding protein 1 Transcription Factor Info

Tissue

Liver

Related DT Changes

Direct regulating

Experiment method

TF-transporter regulations were collected from ChIP-Seq datasets.

Detailed Description

Cyclic AMP-responsive element-binding protein 1 (CREB1) can directly bind to the SLC50A1 gene, which in turn affects the expression or function of the drug transporter Sugar transporter SWEET1.

        FOS 

Click to Show/Hide to Show 1 Transcriptional Phenomena      

       Transcriptional Phenomenon1

Direct binding to SLC50A1 gene [5]

TF Protein Name

Protein c-Fos Transcription Factor Info

Tissue

Bone marrow; Breast; Vein

Related DT Changes

Direct regulating

Experiment method

TF-transporter regulations were collected from ChIP-Seq datasets.

Detailed Description

Protein c-Fos (FOS) can directly bind to the SLC50A1 gene, which in turn affects the expression or function of the drug transporter Sugar transporter SWEET1.

        FOSL2 

Click to Show/Hide to Show 1 Transcriptional Phenomena      

       Transcriptional Phenomenon1

Direct binding to SLC50A1 gene [2]

TF Protein Name

Fos-related antigen 2 Transcription Factor Info

Tissue

Brain; Breast; Liver; Lung

Related DT Changes

Direct regulating

Experiment method

TF-transporter regulations were collected from ChIP-Seq datasets.

Detailed Description

Fos-related antigen 2 (FOSL2) can directly bind to the SLC50A1 gene, which in turn affects the expression or function of the drug transporter Sugar transporter SWEET1.

        JUNB 

Click to Show/Hide to Show 1 Transcriptional Phenomena      

       Transcriptional Phenomenon1

Direct binding to SLC50A1 gene [4]

TF Protein Name

Transcription factor JunB Transcription Factor Info

Tissue

Aorta

Related DT Changes

Direct regulating

Experiment method

TF-transporter regulations were collected from ChIP-Seq datasets.

Detailed Description

Transcription factor JunB (JUNB) can directly bind to the SLC50A1 gene, which in turn affects the expression or function of the drug transporter Sugar transporter SWEET1.

        JUND 

Click to Show/Hide to Show 1 Transcriptional Phenomena      

       Transcriptional Phenomenon1

Direct binding to SLC50A1 gene [5]

TF Protein Name

Transcription factor JunD Transcription Factor Info

Tissue

Bone marrow; Breast; Cervix; Colon; Coronary artery; Embryo; Liver; Lung; Prostate

Related DT Changes

Direct regulating

Experiment method

TF-transporter regulations were collected from ChIP-Seq datasets.

Detailed Description

Transcription factor JunD (JUND) can directly bind to the SLC50A1 gene, which in turn affects the expression or function of the drug transporter Sugar transporter SWEET1.

        NFE2 

Click to Show/Hide to Show 1 Transcriptional Phenomena      

       Transcriptional Phenomenon1

Direct binding to SLC50A1 gene [4]

TF Protein Name

Transcription factor NF-E2 45 kDa subunit Transcription Factor Info

Tissue

Liver

Related DT Changes

Direct regulating

Experiment method

TF-transporter regulations were collected from ChIP-Seq datasets.

Detailed Description

Transcription factor NF-E2 45 kDa subunit (NFE2) can directly bind to the SLC50A1 gene, which in turn affects the expression or function of the drug transporter Sugar transporter SWEET1.

      Class1.2: Basic helix-loop-helix factors

Click to Show/Hide the Full List of 12 TF(s) Regulating This DT

        ARNT 

Click to Show/Hide to Show 1 Transcriptional Phenomena      

       Transcriptional Phenomenon1

Direct binding to SLC50A1 gene [5]

TF Protein Name

Aryl hydrocarbon receptor nuclear translocator Transcription Factor Info

Tissue

Breast

Related DT Changes

Direct regulating

Experiment method

TF-transporter regulations were collected from ChIP-Seq datasets.

Detailed Description

Aryl hydrocarbon receptor nuclear translocator (ARNT) can directly bind to the SLC50A1 gene, which in turn affects the expression or function of the drug transporter Sugar transporter SWEET1.

        BHLHE40 

Click to Show/Hide to Show 1 Transcriptional Phenomena      

       Transcriptional Phenomenon1

Direct binding to SLC50A1 gene [3]

TF Protein Name

Class E basic helix-loop-helix protein 40 Transcription Factor Info

Tissue

Bone marrow; Liver

Related DT Changes

Direct regulating

Experiment method

TF-transporter regulations were collected from ChIP-Seq datasets.

Detailed Description

Class E basic helix-loop-helix protein 40 (BHLHE40) can directly bind to the SLC50A1 gene, which in turn affects the expression or function of the drug transporter Sugar transporter SWEET1.

        HEY1 

Click to Show/Hide to Show 1 Transcriptional Phenomena      

       Transcriptional Phenomenon1

Direct binding to SLC50A1 gene [3]

TF Protein Name

Hairy/enhancer-of-split related with YRPW motif protein 1 Transcription Factor Info

Tissue

Bone marrow

Related DT Changes

Direct regulating

Experiment method

TF-transporter regulations were collected from ChIP-Seq datasets.

Detailed Description

Hairy/enhancer-of-split related with YRPW motif protein 1 (HEY1) can directly bind to the SLC50A1 gene, which in turn affects the expression or function of the drug transporter Sugar transporter SWEET1.

        MAX 

Click to Show/Hide to Show 1 Transcriptional Phenomena      

       Transcriptional Phenomenon1

Direct binding to SLC50A1 gene [2]

TF Protein Name

Protein max Transcription Factor Info

Tissue

Bone marrow; Brain; Breast; Cervix; Colon; Liver

Related DT Changes

Direct regulating

Experiment method

TF-transporter regulations were collected from ChIP-Seq datasets.

Detailed Description

Protein max (MAX) can directly bind to the SLC50A1 gene, which in turn affects the expression or function of the drug transporter Sugar transporter SWEET1.

        MXI1 

Click to Show/Hide to Show 1 Transcriptional Phenomena      

       Transcriptional Phenomenon1

Direct binding to SLC50A1 gene [3]

TF Protein Name

Max-interacting protein 1 Transcription Factor Info

Tissue

Bone marrow; Cervix; Liver

Related DT Changes

Direct regulating

Experiment method

TF-transporter regulations were collected from ChIP-Seq datasets.

Detailed Description

Max-interacting protein 1 (MXI1) can directly bind to the SLC50A1 gene, which in turn affects the expression or function of the drug transporter Sugar transporter SWEET1.

        MYCN 

Click to Show/Hide to Show 1 Transcriptional Phenomena      

       Transcriptional Phenomenon1

Activation of SLC50A1 gene in neuroblastoma condition [6]

TF Protein Name

N-myc proto-oncogene protein Transcription Factor Info

Studied Phenotype

.

Related DT Changes

Up regulating

Detailed Description

N-myc proto-oncogene protein (MYCN) has been reported to activate the transcription of SLC50A1 gene in neuroblastoma condition, which leads to an increased expression of the drug transporter Sugar transporter SWEET1.

        MYOD1 

Click to Show/Hide to Show 1 Transcriptional Phenomena      

       Transcriptional Phenomenon1

Direct binding to SLC50A1 gene [4]

TF Protein Name

Myoblast determination protein 1 Transcription Factor Info

Tissue

Myotube

Related DT Changes

Direct regulating

Experiment method

TF-transporter regulations were collected from ChIP-Seq datasets.

Detailed Description

Myoblast determination protein 1 (MYOD1) can directly bind to the SLC50A1 gene, which in turn affects the expression or function of the drug transporter Sugar transporter SWEET1.

        TCF12 

Click to Show/Hide to Show 1 Transcriptional Phenomena      

       Transcriptional Phenomenon1

Direct binding to SLC50A1 gene [5]

TF Protein Name

Transcription factor 12 Transcription Factor Info

Tissue

Blood; Breast; Embryo; Liver; Lung; Uterus

Related DT Changes

Direct regulating

Experiment method

TF-transporter regulations were collected from ChIP-Seq datasets.

Detailed Description

Transcription factor 12 (TCF12) can directly bind to the SLC50A1 gene, which in turn affects the expression or function of the drug transporter Sugar transporter SWEET1.

        TCF21 

Click to Show/Hide to Show 1 Transcriptional Phenomena      

       Transcriptional Phenomenon1

Direct binding to SLC50A1 gene [5]

TF Protein Name

Transcription factor 21 Transcription Factor Info

Tissue

Coronary artery

Related DT Changes

Direct regulating

Experiment method

TF-transporter regulations were collected from ChIP-Seq datasets.

Detailed Description

Transcription factor 21 (TCF21) can directly bind to the SLC50A1 gene, which in turn affects the expression or function of the drug transporter Sugar transporter SWEET1.

        TCF3 

Click to Show/Hide to Show 1 Transcriptional Phenomena      

       Transcriptional Phenomenon1

Direct binding to SLC50A1 gene [2]

TF Protein Name

Transcription factor E2-alpha Transcription Factor Info

Tissue

Blood

Related DT Changes

Direct regulating

Experiment method

TF-transporter regulations were collected from ChIP-Seq datasets.

Detailed Description

Transcription factor E2-alpha (TCF3) can directly bind to the SLC50A1 gene, which in turn affects the expression or function of the drug transporter Sugar transporter SWEET1.

        TFAP4 

Click to Show/Hide to Show 1 Transcriptional Phenomena      

       Transcriptional Phenomenon1

Direct binding to SLC50A1 gene [3]

TF Protein Name

Transcription factor AP-4 Transcription Factor Info

Tissue

Blood; Prostate

Related DT Changes

Direct regulating

Experiment method

TF-transporter regulations were collected from ChIP-Seq datasets.

Detailed Description

Transcription factor AP-4 (TFAP4) can directly bind to the SLC50A1 gene, which in turn affects the expression or function of the drug transporter Sugar transporter SWEET1.

        USF1 

Click to Show/Hide to Show 1 Transcriptional Phenomena      

       Transcriptional Phenomenon1

Direct binding to SLC50A1 gene [2]

TF Protein Name

Upstream stimulatory factor 1 Transcription Factor Info

Tissue

Liver

Related DT Changes

Direct regulating

Experiment method

TF-transporter regulations were collected from ChIP-Seq datasets.

Detailed Description

Upstream stimulatory factor 1 (USF1) can directly bind to the SLC50A1 gene, which in turn affects the expression or function of the drug transporter Sugar transporter SWEET1.

      Class1.3: Basic helix-span-helix factors

Click to Show/Hide the Full List of 2 TF(s) Regulating This DT

        TFAP2A 

Click to Show/Hide to Show 1 Transcriptional Phenomena      

       Transcriptional Phenomenon1

Direct binding to SLC50A1 gene [3]

TF Protein Name

Transcription factor AP-2-alpha Transcription Factor Info

Tissue

Breast; Cervix

Related DT Changes

Direct regulating

Experiment method

TF-transporter regulations were collected from ChIP-Seq datasets.

Detailed Description

Transcription factor AP-2-alpha (TFAP2A) can directly bind to the SLC50A1 gene, which in turn affects the expression or function of the drug transporter Sugar transporter SWEET1.

        TFAP2C 

Click to Show/Hide to Show 1 Transcriptional Phenomena      

       Transcriptional Phenomenon1

Direct binding to SLC50A1 gene [4]

TF Protein Name

Transcription factor AP-2 gamma Transcription Factor Info

Tissue

Breast; Cervix; Skin

Related DT Changes

Direct regulating

Experiment method

TF-transporter regulations were collected from ChIP-Seq datasets.

Detailed Description

Transcription factor AP-2 gamma (TFAP2C) can directly bind to the SLC50A1 gene, which in turn affects the expression or function of the drug transporter Sugar transporter SWEET1.

TF Superclass2: Zinc-coordinating DNA-binding domains

      Class2.1: Nuclear receptors with C4 zinc fingers

Click to Show/Hide the Full List of 7 TF(s) Regulating This DT

        AR 

Click to Show/Hide to Show 1 Transcriptional Phenomena      

       Transcriptional Phenomenon1

Direct binding to SLC50A1 gene [2]

TF Protein Name

Androgen receptor Transcription Factor Info

Tissue

Breast; Cervix; Kidney; Prostate

Related DT Changes

Direct regulating

Experiment method

TF-transporter regulations were collected from ChIP-Seq datasets.

Detailed Description

Androgen receptor (AR) can directly bind to the SLC50A1 gene, which in turn affects the expression or function of the drug transporter Sugar transporter SWEET1.

        ESR1 

Click to Show/Hide to Show 1 Transcriptional Phenomena      

       Transcriptional Phenomenon1

Direct binding to SLC50A1 gene [3]

TF Protein Name

Estrogen receptor Transcription Factor Info

Tissue

Breast

Related DT Changes

Direct regulating

Experiment method

TF-transporter regulations were collected from ChIP-Seq datasets.

Detailed Description

Estrogen receptor (ESR1) can directly bind to the SLC50A1 gene, which in turn affects the expression or function of the drug transporter Sugar transporter SWEET1.

        HNF4A 

Click to Show/Hide to Show 1 Transcriptional Phenomena      

       Transcriptional Phenomenon1

Direct binding to SLC50A1 gene [2]

TF Protein Name

Hepatocyte nuclear factor 4-alpha Transcription Factor Info

Tissue

Colon; Intestine; Liver

Related DT Changes

Direct regulating

Experiment method

TF-transporter regulations were collected from ChIP-Seq datasets.

Detailed Description

Hepatocyte nuclear factor 4-alpha (HNF4A) can directly bind to the SLC50A1 gene, which in turn affects the expression or function of the drug transporter Sugar transporter SWEET1.

        HNF4G 

Click to Show/Hide to Show 1 Transcriptional Phenomena      

       Transcriptional Phenomenon1

Direct binding to SLC50A1 gene [4]

TF Protein Name

Hepatocyte nuclear factor 4-gamma Transcription Factor Info

Tissue

Liver

Related DT Changes

Direct regulating

Experiment method

TF-transporter regulations were collected from ChIP-Seq datasets.

Detailed Description

Hepatocyte nuclear factor 4-gamma (HNF4G) can directly bind to the SLC50A1 gene, which in turn affects the expression or function of the drug transporter Sugar transporter SWEET1.

        NR2C2 

Click to Show/Hide to Show 1 Transcriptional Phenomena      

       Transcriptional Phenomenon1

Direct binding to SLC50A1 gene [4]

TF Protein Name

Nuclear receptor subfamily 2 group C member 2 Transcription Factor Info

Tissue

Cervix; Liver

Related DT Changes

Direct regulating

Experiment method

TF-transporter regulations were collected from ChIP-Seq datasets.

Detailed Description

Nuclear receptor subfamily 2 group C member 2 (NR2C2) can directly bind to the SLC50A1 gene, which in turn affects the expression or function of the drug transporter Sugar transporter SWEET1.

        NR2F2 

Click to Show/Hide to Show 1 Transcriptional Phenomena      

       Transcriptional Phenomenon1

Direct binding to SLC50A1 gene [5]

TF Protein Name

COUP transcription factor 2 Transcription Factor Info

Tissue

Bone marrow; Breast; Liver

Related DT Changes

Direct regulating

Experiment method

TF-transporter regulations were collected from ChIP-Seq datasets.

Detailed Description

COUP transcription factor 2 (NR2F2) can directly bind to the SLC50A1 gene, which in turn affects the expression or function of the drug transporter Sugar transporter SWEET1.

        RXRA 

Click to Show/Hide to Show 1 Transcriptional Phenomena      

       Transcriptional Phenomenon1

Direct binding to SLC50A1 gene [2]

TF Protein Name

Retinoic acid receptor RXR-alpha Transcription Factor Info

Tissue

Colon; Liver

Related DT Changes

Direct regulating

Experiment method

TF-transporter regulations were collected from ChIP-Seq datasets.

Detailed Description

Retinoic acid receptor RXR-alpha (RXRA) can directly bind to the SLC50A1 gene, which in turn affects the expression or function of the drug transporter Sugar transporter SWEET1.

      Class2.2: Other C4 zinc finger-type factors

Click to Show/Hide the Full List of 3 TF(s) Regulating This DT

        GATA1 

Click to Show/Hide to Show 1 Transcriptional Phenomena      

       Transcriptional Phenomenon1

Direct binding to SLC50A1 gene [4]

TF Protein Name

Erythroid transcription factor Transcription Factor Info

Tissue

Blood; Bone marrow

Related DT Changes

Direct regulating

Experiment method

TF-transporter regulations were collected from ChIP-Seq datasets.

Detailed Description

Erythroid transcription factor (GATA1) can directly bind to the SLC50A1 gene, which in turn affects the expression or function of the drug transporter Sugar transporter SWEET1.

        GATA2 

Click to Show/Hide to Show 1 Transcriptional Phenomena      

       Transcriptional Phenomenon1

Activation of SLC50A1 gene in health condition [7]

TF Protein Name

Endothelial transcription factor GATA-2 Transcription Factor Info

Studied Phenotype

.

Related DT Changes

Up regulating

Detailed Description

Endothelial transcription factor GATA-2 (GATA2) has been reported to activate the transcription of SLC50A1 gene in health condition, which leads to an increased expression of the drug transporter Sugar transporter SWEET1.

        GATA3 

Click to Show/Hide to Show 1 Transcriptional Phenomena      

       Transcriptional Phenomenon1

Direct binding to SLC50A1 gene [5]

TF Protein Name

Trans-acting T-cell-specific transcription factor GATA-3 Transcription Factor Info

Tissue

Blood; Breast; Lung

Related DT Changes

Direct regulating

Experiment method

TF-transporter regulations were collected from ChIP-Seq datasets.

Detailed Description

Trans-acting T-cell-specific transcription factor GATA-3 (GATA3) can directly bind to the SLC50A1 gene, which in turn affects the expression or function of the drug transporter Sugar transporter SWEET1.

      Class2.3: C2H2 zinc finger factors

Click to Show/Hide the Full List of 14 TF(s) Regulating This DT

        BCL6 

Click to Show/Hide to Show 1 Transcriptional Phenomena      

       Transcriptional Phenomenon1

Direct binding to SLC50A1 gene [3]

TF Protein Name

B-cell lymphoma 6 protein Transcription Factor Info

Tissue

Blood; Tonsil

Related DT Changes

Direct regulating

Experiment method

TF-transporter regulations were collected from ChIP-Seq datasets.

Detailed Description

B-cell lymphoma 6 protein (BCL6) can directly bind to the SLC50A1 gene, which in turn affects the expression or function of the drug transporter Sugar transporter SWEET1.

        CTCF 

Click to Show/Hide to Show 1 Transcriptional Phenomena      

       Transcriptional Phenomenon1

Direct binding to SLC50A1 gene [5]

TF Protein Name

Transcriptional repressor CTCF Transcription Factor Info

Tissue

Striated muscle

Related DT Changes

Direct regulating

Experiment method

TF-transporter regulations were collected from ChIP-Seq datasets.

Detailed Description

Transcriptional repressor CTCF (CTCF) can directly bind to the SLC50A1 gene, which in turn affects the expression or function of the drug transporter Sugar transporter SWEET1.

        EGR1 

Click to Show/Hide to Show 2 Transcriptional Phenomena      

       Transcriptional Phenomenon1

Binding to SLC50A1 gene in erythroleukemia condition [8]

TF Protein Name

Early growth response protein 1 Transcription Factor Info

Studied Phenotype

.

Related DT Changes

Direct regulating

Detailed Description

Early growth response protein 1 (EGR1) has been reported to bind to the transcription of SLC50A1 gene in erythroleukemia condition, which leads to an affected expression of the drug transporter Sugar transporter SWEET1.

       Transcriptional Phenomenon2

Direct binding to SLC50A1 gene [2]

TF Protein Name

Early growth response protein 1 Transcription Factor Info

Tissue

Blood; Bone marrow; Breast; Colon; Embryo; Uterus

Related DT Changes

Direct regulating

Experiment method

TF-transporter regulations were collected from ChIP-Seq datasets.

Detailed Description

Early growth response protein 1 (EGR1) can directly bind to the SLC50A1 gene, which in turn affects the expression or function of the drug transporter Sugar transporter SWEET1.

        KLF1 

Click to Show/Hide to Show 1 Transcriptional Phenomena      

       Transcriptional Phenomenon1

Direct binding to SLC50A1 gene [3]

TF Protein Name

Krueppel-like factor 1 Transcription Factor Info

Tissue

Blood

Related DT Changes

Direct regulating

Experiment method

TF-transporter regulations were collected from ChIP-Seq datasets.

Detailed Description

Krueppel-like factor 1 (KLF1) can directly bind to the SLC50A1 gene, which in turn affects the expression or function of the drug transporter Sugar transporter SWEET1.

        KLF4 

Click to Show/Hide to Show 1 Transcriptional Phenomena      

       Transcriptional Phenomenon1

Direct binding to SLC50A1 gene [4]

TF Protein Name

Krueppel-like factor 4 Transcription Factor Info

Tissue

Foreskin; Pancreatic ductal; Skin

Related DT Changes

Direct regulating

Experiment method

TF-transporter regulations were collected from ChIP-Seq datasets.

Detailed Description

Krueppel-like factor 4 (KLF4) can directly bind to the SLC50A1 gene, which in turn affects the expression or function of the drug transporter Sugar transporter SWEET1.

        KLF5 

Click to Show/Hide to Show 2 Transcriptional Phenomena      

       Transcriptional Phenomenon1

Activation of SLC50A1 gene in gastric cancer condition [9]

TF Protein Name

Krueppel-like factor 5 Transcription Factor Info

Studied Phenotype

.

Related DT Changes

Up regulating

Detailed Description

Krueppel-like factor 5 (KLF5) has been reported to activate the transcription of SLC50A1 gene in gastric cancer condition, which leads to an increased expression of the drug transporter Sugar transporter SWEET1.

       Transcriptional Phenomenon2

Direct binding to SLC50A1 gene [5]

TF Protein Name

Krueppel-like factor 5 Transcription Factor Info

Tissue

Colon; Pancreatic ductal; Stomach

Related DT Changes

Direct regulating

Experiment method

TF-transporter regulations were collected from ChIP-Seq datasets.

Detailed Description

Krueppel-like factor 5 (KLF5) can directly bind to the SLC50A1 gene, which in turn affects the expression or function of the drug transporter Sugar transporter SWEET1.

        KLF9 

Click to Show/Hide to Show 1 Transcriptional Phenomena      

       Transcriptional Phenomenon1

Direct binding to SLC50A1 gene [2]

TF Protein Name

Krueppel-like factor 9 Transcription Factor Info

Related DT Changes

Direct regulating

Experiment method

TF-transporter regulations were collected from ChIP-Seq datasets.

Detailed Description

Krueppel-like factor 9 (KLF9) can directly bind to the SLC50A1 gene, which in turn affects the expression or function of the drug transporter Sugar transporter SWEET1.

        MAZ 

Click to Show/Hide to Show 1 Transcriptional Phenomena      

       Transcriptional Phenomenon1

Direct binding to SLC50A1 gene [5]

TF Protein Name

Myc-associated zinc finger protein Transcription Factor Info

Tissue

Blood; Bone marrow; Cervix; Liver; Lung

Related DT Changes

Direct regulating

Experiment method

TF-transporter regulations were collected from ChIP-Seq datasets.

Detailed Description

Myc-associated zinc finger protein (MAZ) can directly bind to the SLC50A1 gene, which in turn affects the expression or function of the drug transporter Sugar transporter SWEET1.

        MECOM 

Click to Show/Hide to Show 1 Transcriptional Phenomena      

       Transcriptional Phenomenon1

Direct binding to SLC50A1 gene [3]

TF Protein Name

Histone-lysine N-methyltransferase MECOM Transcription Factor Info

Tissue

Colon

Related DT Changes

Direct regulating

Experiment method

TF-transporter regulations were collected from ChIP-Seq datasets.

Detailed Description

Histone-lysine N-methyltransferase MECOM (MECOM) can directly bind to the SLC50A1 gene, which in turn affects the expression or function of the drug transporter Sugar transporter SWEET1.

        SP1 

Click to Show/Hide to Show 1 Transcriptional Phenomena      

       Transcriptional Phenomenon1

Direct binding to SLC50A1 gene [3]

TF Protein Name

Transcription factor Sp1 Transcription Factor Info

Tissue

Blood; Colon; Embryo; Liver; Lung

Related DT Changes

Direct regulating

Experiment method

TF-transporter regulations were collected from ChIP-Seq datasets.

Detailed Description

Transcription factor Sp1 (SP1) can directly bind to the SLC50A1 gene, which in turn affects the expression or function of the drug transporter Sugar transporter SWEET1.

        SP4 

Click to Show/Hide to Show 1 Transcriptional Phenomena      

       Transcriptional Phenomenon1

Direct binding to SLC50A1 gene [4]

TF Protein Name

Transcription factor Sp4 Transcription Factor Info

Tissue

Embryo

Related DT Changes

Direct regulating

Experiment method

TF-transporter regulations were collected from ChIP-Seq datasets.

Detailed Description

Transcription factor Sp4 (SP4) can directly bind to the SLC50A1 gene, which in turn affects the expression or function of the drug transporter Sugar transporter SWEET1.

        VEZF1 

Click to Show/Hide to Show 1 Transcriptional Phenomena      

       Transcriptional Phenomenon1

Direct binding to SLC50A1 gene [2]

TF Protein Name

Vascular endothelial zinc finger 1 Transcription Factor Info

Tissue

Colon

Related DT Changes

Direct regulating

Experiment method

TF-transporter regulations were collected from ChIP-Seq datasets.

Detailed Description

Vascular endothelial zinc finger 1 (VEZF1) can directly bind to the SLC50A1 gene, which in turn affects the expression or function of the drug transporter Sugar transporter SWEET1.

        ZBTB7A 

Click to Show/Hide to Show 1 Transcriptional Phenomena      

       Transcriptional Phenomenon1

Direct binding to SLC50A1 gene [5]

TF Protein Name

Zinc finger and BTB domain-containing protein 7A Transcription Factor Info

Tissue

Bone marrow; Liver; Uterus

Related DT Changes

Direct regulating

Experiment method

TF-transporter regulations were collected from ChIP-Seq datasets.

Detailed Description

Zinc finger and BTB domain-containing protein 7A (ZBTB7A) can directly bind to the SLC50A1 gene, which in turn affects the expression or function of the drug transporter Sugar transporter SWEET1.

        ZNF263 

Click to Show/Hide to Show 1 Transcriptional Phenomena      

       Transcriptional Phenomenon1

Direct binding to SLC50A1 gene [3]

TF Protein Name

Zinc finger protein 263 Transcription Factor Info

Tissue

Bone marrow; Kidney

Related DT Changes

Direct regulating

Experiment method

TF-transporter regulations were collected from ChIP-Seq datasets.

Detailed Description

Zinc finger protein 263 (ZNF263) can directly bind to the SLC50A1 gene, which in turn affects the expression or function of the drug transporter Sugar transporter SWEET1.

TF Superclass3: Helix-turn-helix domains

      Class3.1: Homeo domain factors

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        NKX2-1 

Click to Show/Hide to Show 1 Transcriptional Phenomena      

       Transcriptional Phenomenon1

Direct binding to SLC50A1 gene [5]

TF Protein Name

Homeobox protein Nkx-2.1 Transcription Factor Info

Tissue

Lung

Related DT Changes

Direct regulating

Experiment method

TF-transporter regulations were collected from ChIP-Seq datasets.

Detailed Description

Homeobox protein Nkx-2.1 (NKX2-1) can directly bind to the SLC50A1 gene, which in turn affects the expression or function of the drug transporter Sugar transporter SWEET1.

      Class3.3: Fork head / winged helix factors

Click to Show/Hide the Full List of 6 TF(s) Regulating This DT

        E2F1 

Click to Show/Hide to Show 1 Transcriptional Phenomena      

       Transcriptional Phenomenon1

Direct binding to SLC50A1 gene [5]

TF Protein Name

Transcription factor E2F1 Transcription Factor Info

Tissue

Mesenchymal

Related DT Changes

Direct regulating

Experiment method

TF-transporter regulations were collected from ChIP-Seq datasets.

Detailed Description

Transcription factor E2F1 (E2F1) can directly bind to the SLC50A1 gene, which in turn affects the expression or function of the drug transporter Sugar transporter SWEET1.

        E2F4 

Click to Show/Hide to Show 1 Transcriptional Phenomena      

       Transcriptional Phenomenon1

Binding to SLC50A1 gene in health condition [10]

TF Protein Name

Transcription factor E2F4 Transcription Factor Info

Studied Phenotype

.

Related DT Changes

Direct regulating

Detailed Description

Transcription factor E2F4 (E2F4) has been reported to bind to the transcription of SLC50A1 gene in health condition, which leads to an affected expression of the drug transporter Sugar transporter SWEET1.

        E2F6 

Click to Show/Hide to Show 1 Transcriptional Phenomena      

       Transcriptional Phenomenon1

Direct binding to SLC50A1 gene [2]

TF Protein Name

Transcription factor E2F6 Transcription Factor Info

Tissue

Bone marrow; Embryo; Lung

Related DT Changes

Direct regulating

Experiment method

TF-transporter regulations were collected from ChIP-Seq datasets.

Detailed Description

Transcription factor E2F6 (E2F6) can directly bind to the SLC50A1 gene, which in turn affects the expression or function of the drug transporter Sugar transporter SWEET1.

        FOXA1 

Click to Show/Hide to Show 1 Transcriptional Phenomena      

       Transcriptional Phenomenon1

Direct binding to SLC50A1 gene [5]

TF Protein Name

Hepatocyte nuclear factor 3-alpha Transcription Factor Info

Tissue

Breast; Embryo; Liver; Lung; Pancreatic ductal; Prostate

Related DT Changes

Direct regulating

Experiment method

TF-transporter regulations were collected from ChIP-Seq datasets.

Detailed Description

Hepatocyte nuclear factor 3-alpha (FOXA1) can directly bind to the SLC50A1 gene, which in turn affects the expression or function of the drug transporter Sugar transporter SWEET1.

        FOXA2 

Click to Show/Hide to Show 1 Transcriptional Phenomena      

       Transcriptional Phenomenon1

Direct binding to SLC50A1 gene [2]

TF Protein Name

Hepatocyte nuclear factor 3-beta Transcription Factor Info

Tissue

Colon

Related DT Changes

Direct regulating

Experiment method

TF-transporter regulations were collected from ChIP-Seq datasets.

Detailed Description

Hepatocyte nuclear factor 3-beta (FOXA2) can directly bind to the SLC50A1 gene, which in turn affects the expression or function of the drug transporter Sugar transporter SWEET1.

        FOXP1 

Click to Show/Hide to Show 1 Transcriptional Phenomena      

       Transcriptional Phenomenon1

Direct binding to SLC50A1 gene [2]

TF Protein Name

Forkhead box protein P1 Transcription Factor Info

Tissue

Colon; Embryo

Related DT Changes

Direct regulating

Experiment method

TF-transporter regulations were collected from ChIP-Seq datasets.

Detailed Description

Forkhead box protein P1 (FOXP1) can directly bind to the SLC50A1 gene, which in turn affects the expression or function of the drug transporter Sugar transporter SWEET1.

      Class3.5: Tryptophan cluster factors

Click to Show/Hide the Full List of 9 TF(s) Regulating This DT

        ELK1 

Click to Show/Hide to Show 1 Transcriptional Phenomena      

       Transcriptional Phenomenon1

Binding to SLC50A1 gene in . condition [11]

TF Protein Name

ETS domain-containing protein Elk-1 Transcription Factor Info

Related DT Changes

Direct regulating

Detailed Description

ETS domain-containing protein Elk-1 (ELK1) has been reported to bind to the SLC50A1 gene in . condition, which leads to a affected expression of the drug transporter Sugar transporter SWEET1.

        ELK3 

Click to Show/Hide to Show 1 Transcriptional Phenomena      

       Transcriptional Phenomenon1

Binding to SLC50A1 gene in hypoxia condition [12]

TF Protein Name

ETS domain-containing protein Elk-3 Transcription Factor Info

Studied Phenotype

.

Related DT Changes

Direct regulating

Detailed Description

ETS domain-containing protein Elk-3 (ELK3) has been reported to bind to the transcription of SLC50A1 gene in hypoxia condition, which leads to an affected expression of the drug transporter Sugar transporter SWEET1.

        ERG 

Click to Show/Hide to Show 1 Transcriptional Phenomena      

       Transcriptional Phenomenon1

Direct binding to SLC50A1 gene [3]

TF Protein Name

Transcriptional regulator ERG Transcription Factor Info

Tissue

Aorta

Related DT Changes

Direct regulating

Experiment method

TF-transporter regulations were collected from ChIP-Seq datasets.

Detailed Description

Transcriptional regulator ERG (ERG) can directly bind to the SLC50A1 gene, which in turn affects the expression or function of the drug transporter Sugar transporter SWEET1.

        ETS1 

Click to Show/Hide to Show 1 Transcriptional Phenomena      

       Transcriptional Phenomenon1

Direct binding to SLC50A1 gene [4]

TF Protein Name

Protein C-ets-1 Transcription Factor Info

Tissue

Blood; Bone; Bone marrow; Kidney; Lung; Prostate; Vein

Related DT Changes

Direct regulating

Experiment method

TF-transporter regulations were collected from ChIP-Seq datasets.

Detailed Description

Protein C-ets-1 (ETS1) can directly bind to the SLC50A1 gene, which in turn affects the expression or function of the drug transporter Sugar transporter SWEET1.

        FLI1 

Click to Show/Hide to Show 2 Transcriptional Phenomena      

       Transcriptional Phenomenon1

Binding to SLC50A1 gene in megakaryocytes condition [13]

TF Protein Name

Friend leukemia integration 1 transcription factor Transcription Factor Info

Related DT Changes

Direct regulating

Detailed Description

Friend leukemia integration 1 transcription factor (FLI1) has been reported to bind to the transcription of SLC50A1 gene in megakaryocytes condition, which leads to an affected expression of the drug transporter Sugar transporter SWEET1.

       Transcriptional Phenomenon2

Direct binding to SLC50A1 gene [5]

TF Protein Name

Friend leukemia integration 1 transcription factor Transcription Factor Info

Tissue

Blood; Mesenchymal; Umbilical cord blood; Vein

Related DT Changes

Direct regulating

Experiment method

TF-transporter regulations were collected from ChIP-Seq datasets.

Detailed Description

Friend leukemia integration 1 transcription factor (FLI1) can directly bind to the SLC50A1 gene, which in turn affects the expression or function of the drug transporter Sugar transporter SWEET1.

        GABPA 

Click to Show/Hide to Show 1 Transcriptional Phenomena      

       Transcriptional Phenomenon1

Direct binding to SLC50A1 gene [3]

TF Protein Name

GA-binding protein alpha chain Transcription Factor Info

Tissue

Blood; Bone; Bone marrow; Brain; Breast; Cervix; Embryo; Liver; Lung; Mesenchymal; Prostate

Related DT Changes

Direct regulating

Experiment method

TF-transporter regulations were collected from ChIP-Seq datasets.

Detailed Description

GA-binding protein alpha chain (GABPA) can directly bind to the SLC50A1 gene, which in turn affects the expression or function of the drug transporter Sugar transporter SWEET1.

        IRF1 

Click to Show/Hide to Show 1 Transcriptional Phenomena      

       Transcriptional Phenomenon1

Direct binding to SLC50A1 gene [3]

TF Protein Name

Interferon regulatory factor 1 Transcription Factor Info

Tissue

Bone marrow; Pancreatic ductal

Related DT Changes

Direct regulating

Experiment method

TF-transporter regulations were collected from ChIP-Seq datasets.

Detailed Description

Interferon regulatory factor 1 (IRF1) can directly bind to the SLC50A1 gene, which in turn affects the expression or function of the drug transporter Sugar transporter SWEET1.

        MYB 

Click to Show/Hide to Show 1 Transcriptional Phenomena      

       Transcriptional Phenomenon1

Direct binding to SLC50A1 gene [4]

TF Protein Name

Transcriptional activator Myb Transcription Factor Info

Tissue

Blood

Related DT Changes

Direct regulating

Experiment method

TF-transporter regulations were collected from ChIP-Seq datasets.

Detailed Description

Transcriptional activator Myb (MYB) can directly bind to the SLC50A1 gene, which in turn affects the expression or function of the drug transporter Sugar transporter SWEET1.

        SPI1 

Click to Show/Hide to Show 2 Transcriptional Phenomena      

       Transcriptional Phenomenon1

Binding to SLC50A1 gene in acute myeloid leukemia condition [14]

TF Protein Name

Transcription factor PU.1 Transcription Factor Info

Studied Phenotype

.

Related DT Changes

Direct regulating

Detailed Description

Transcription factor PU.1 (SPI1) has been reported to bind to the transcription of SLC50A1 gene in acute myeloid leukemia condition, which leads to an affected expression of the drug transporter Sugar transporter SWEET1.

       Transcriptional Phenomenon2

Direct binding to SLC50A1 gene [2]

TF Protein Name

Transcription factor PU.1 Transcription Factor Info

Tissue

Adrenal gland; Blood; Bone marrow; Brain; Breast; Embryo; Foreskin; Heart; Intestine; Kidney; Lung; Muscle; Penis; Placenta; Renal cortex; Renal pelvis; Skin; Spinal cord; Stomach; Testes; Umbilical cord blood

Related DT Changes

Direct regulating

Experiment method

TF-transporter regulations were collected from ChIP-Seq datasets.

Detailed Description

Transcription factor PU.1 (SPI1) can directly bind to the SLC50A1 gene, which in turn affects the expression or function of the drug transporter Sugar transporter SWEET1.

      Class3.7: ARID domain factors

Click to Show/Hide the Full List of 1 TF(s) Regulating This DT

        KDM5B 

Click to Show/Hide to Show 1 Transcriptional Phenomena      

       Transcriptional Phenomenon1

Direct binding to SLC50A1 gene [4]

TF Protein Name

Lysine-specific demethylase 5B Transcription Factor Info

Tissue

Bone marrow; Breast

Related DT Changes

Direct regulating

Experiment method

TF-transporter regulations were collected from ChIP-Seq datasets.

Detailed Description

Lysine-specific demethylase 5B (KDM5B) can directly bind to the SLC50A1 gene, which in turn affects the expression or function of the drug transporter Sugar transporter SWEET1.

TF Superclass4: Other all-alpha-helical DNA-binding domains

      Class4.2: Heteromeric CCAAT-binding factors

Click to Show/Hide the Full List of 1 TF(s) Regulating This DT

        NFYA 

Click to Show/Hide to Show 1 Transcriptional Phenomena      

       Transcriptional Phenomenon1

Direct binding to SLC50A1 gene [2]

TF Protein Name

Nuclear transcription factor Y subunit alpha Transcription Factor Info

Tissue

Bone marrow

Related DT Changes

Direct regulating

Experiment method

TF-transporter regulations were collected from ChIP-Seq datasets.

Detailed Description

Nuclear transcription factor Y subunit alpha (NFYA) can directly bind to the SLC50A1 gene, which in turn affects the expression or function of the drug transporter Sugar transporter SWEET1.

TF Superclass5: alpha-Helices exposed by beta-structures

      Class5.1: MADS box factors

Click to Show/Hide the Full List of 1 TF(s) Regulating This DT

        SRF 

Click to Show/Hide to Show 1 Transcriptional Phenomena      

       Transcriptional Phenomenon1

Direct binding to SLC50A1 gene [2]

TF Protein Name

Serum response factor Transcription Factor Info

Tissue

Embryo; Uterus

Related DT Changes

Direct regulating

Experiment method

TF-transporter regulations were collected from ChIP-Seq datasets.

Detailed Description

Serum response factor (SRF) can directly bind to the SLC50A1 gene, which in turn affects the expression or function of the drug transporter Sugar transporter SWEET1.

TF Superclass6: Immunoglobulin fold

      Class6.1: Rel homology region factors

Click to Show/Hide the Full List of 1 TF(s) Regulating This DT

        EBF1 

Click to Show/Hide to Show 1 Transcriptional Phenomena      

       Transcriptional Phenomenon1

Direct binding to SLC50A1 gene [4]

TF Protein Name

Transcription factor COE1 Transcription Factor Info

Tissue

Blood

Related DT Changes

Direct regulating

Experiment method

TF-transporter regulations were collected from ChIP-Seq datasets.

Detailed Description

Transcription factor COE1 (EBF1) can directly bind to the SLC50A1 gene, which in turn affects the expression or function of the drug transporter Sugar transporter SWEET1.

      Class6.2: STAT domain factors

Click to Show/Hide the Full List of 1 TF(s) Regulating This DT

        STAT1 

Click to Show/Hide to Show 1 Transcriptional Phenomena      

       Transcriptional Phenomenon1

Direct binding to SLC50A1 gene [3]

TF Protein Name

Signal transducer and activator of transcription 1-alpha/beta Transcription Factor Info

Tissue

Blood; Cervix

Related DT Changes

Direct regulating

Experiment method

TF-transporter regulations were collected from ChIP-Seq datasets.

Detailed Description

Signal transducer and activator of transcription 1-alpha/beta (STAT1) can directly bind to the SLC50A1 gene, which in turn affects the expression or function of the drug transporter Sugar transporter SWEET1.

      Class6.3: p53 domain factors

Click to Show/Hide the Full List of 1 TF(s) Regulating This DT

        TP63 

Click to Show/Hide to Show 1 Transcriptional Phenomena      

       Transcriptional Phenomenon1

Binding to SLC50A1 gene in health condition [15]

TF Protein Name

Tumor protein 63 Transcription Factor Info

Studied Phenotype

.

Related DT Changes

Direct regulating

Detailed Description

Tumor protein 63 (TP63) has been reported to bind to the transcription of SLC50A1 gene in health condition, which leads to an affected expression of the drug transporter Sugar transporter SWEET1.

      Class6.4: Runt domain factors

Click to Show/Hide the Full List of 1 TF(s) Regulating This DT

        RUNX1 

Click to Show/Hide to Show 1 Transcriptional Phenomena      

       Transcriptional Phenomenon1

Binding to SLC50A1 gene in megakaryocytes condition [13]

TF Protein Name

Runt-related transcription factor 1 Transcription Factor Info

Related DT Changes

Direct regulating

Detailed Description

Runt-related transcription factor 1 (RUNX1) has been reported to bind to the transcription of SLC50A1 gene in megakaryocytes condition, which leads to an affected expression of the drug transporter Sugar transporter SWEET1.

      Class6.7: Grainyhead domain factors

Click to Show/Hide the Full List of 1 TF(s) Regulating This DT

        GRHL2 

Click to Show/Hide to Show 1 Transcriptional Phenomena      

       Transcriptional Phenomenon1

Direct binding to SLC50A1 gene [5]

TF Protein Name

Grainyhead-like protein 2 homolog Transcription Factor Info

Tissue

Breast; Bronchus; Ovary

Related DT Changes

Direct regulating

Experiment method

TF-transporter regulations were collected from ChIP-Seq datasets.

Detailed Description

Grainyhead-like protein 2 homolog (GRHL2) can directly bind to the SLC50A1 gene, which in turn affects the expression or function of the drug transporter Sugar transporter SWEET1.

TF Superclass7: beta-Hairpin exposed by an alpha/beta-scaffold

      Class7.1: SMAD/NF-1 DNA-binding domain factors

Click to Show/Hide the Full List of 2 TF(s) Regulating This DT

        NFIC 

Click to Show/Hide to Show 1 Transcriptional Phenomena      

       Transcriptional Phenomenon1

Direct binding to SLC50A1 gene [4]

TF Protein Name

Nuclear factor 1 C-type Transcription Factor Info

Tissue

Liver

Related DT Changes

Direct regulating

Experiment method

TF-transporter regulations were collected from ChIP-Seq datasets.

Detailed Description

Nuclear factor 1 C-type (NFIC) can directly bind to the SLC50A1 gene, which in turn affects the expression or function of the drug transporter Sugar transporter SWEET1.

        SMAD3 

Click to Show/Hide to Show 1 Transcriptional Phenomena      

       Transcriptional Phenomenon1

Binding to SLC50A1 gene in health condition [16]

TF Protein Name

Mothers against decapentaplegic homolog 3 Transcription Factor Info

Studied Phenotype

.

Related DT Changes

Direct regulating

Detailed Description

Mothers against decapentaplegic homolog 3 (SMAD3) has been reported to bind to the transcription of SLC50A1 gene in health condition, which leads to an affected expression of the drug transporter Sugar transporter SWEET1.

TF Superclass10: Yet undefined DNA-binding domains

      Class10.1: Other factors

Click to Show/Hide the Full List of 2 TF(s) Regulating This DT

        MBD3 

Click to Show/Hide to Show 1 Transcriptional Phenomena      

       Transcriptional Phenomenon1

Direct binding to SLC50A1 gene [3]

TF Protein Name

Methyl-CpG-binding domain protein 3 Transcription Factor Info

Tissue

Breast

Related DT Changes

Direct regulating

Experiment method

TF-transporter regulations were collected from ChIP-Seq datasets.

Detailed Description

Methyl-CpG-binding domain protein 3 (MBD3) can directly bind to the SLC50A1 gene, which in turn affects the expression or function of the drug transporter Sugar transporter SWEET1.

        REPIN1 

Click to Show/Hide to Show 1 Transcriptional Phenomena      

       Transcriptional Phenomenon1

Direct binding to SLC50A1 gene [4]

TF Protein Name

Replication initiator 1 Transcription Factor Info

Tissue

Colon

Related DT Changes

Direct regulating

Experiment method

TF-transporter regulations were collected from ChIP-Seq datasets.

Detailed Description

Replication initiator 1 (REPIN1) can directly bind to the SLC50A1 gene, which in turn affects the expression or function of the drug transporter Sugar transporter SWEET1.
References
1 In vivo RNAi screen for BMI1 targets identifies TGF-BMP-ER stress pathways as key regulators of neural- and malignant glioma-stem cell homeostasis. Cancer Cell. 2013;23(5):660-76.
2 hTFtarget: A Comprehensive Database for Regulations of Human Transcription Factors and Their Targets. Genomics Proteomics Bioinformatics. 2020 Apr;18(2):120-387. (ID:ENSG00000169241)
3 NCBI GEO: archive for functional genomics data sets--update. Nucleic Acids Res. 2013 Jan;41(D1):D991-5.
4 Closure of the NCBI SRA and implications for the long-term future of genomics data storage. Genome Biol. 2011;12(3):402.
5 The Encyclopedia of DNA elements (ENCODE): data portal update. Nucleic Acids Res. 2018 Jan 4;46(D1):D794-D801
6 Global MYCN transcription factor binding analysis in neuroblastoma reveals association with distinct E-box motifs and regions of DNA hypermethylation. PLoS One. 2009;4(12):e8154.
7 Discovering hematopoietic mechanisms through genome-wide analysis of GATA factor chromatin occupancy. Mol Cell. 2009;36(4):667-81.
8 Global analysis of in vivo EGR1-binding sites in erythroleukemia cell using chromatin immunoprecipitation and massively parallel sequencing. Electrophoresis. 2010;31(17):2936-43.
9 Regulatory crosstalk between lineage-survival oncogenes KLF5, GATA4 and GATA6 cooperatively promotes gastric cancer development. Gut. 2015;64(5):707-19.
10 Wide-ranging functions of E2F4 in transcriptional activation and repression revealed by genome-wide analysis. Nucleic Acids Res. 2011;39(9):3558-73.
11 Elucidation of the ELK1 target gene network reveals a role in the coordinate regulation of core components of the gene regulation machinery. Genome Res. 2009;19(11):1963-73.
12 The oncogenic MicroRNA Hsa-miR-155-5p targets the transcription factor ELK3 and links it to the hypoxia response. PLoS One. 2014;9(11):e113050.
13 Genome-wide analysis of simultaneous GATA1/2, RUNX1, FLI1, and SCL binding in megakaryocytes identifies hematopoietic regulators. Dev Cell. 2011;20(5):597-609.
14 Structurally differentiated cis-elements that interact with PU.1 are functionally distinguishable in acute promyelocytic leukemia. J Hematol Oncol. 2013;6:25.
15 Genome-wide analysis of p63 binding sites identifies AP-2 factors as co-regulators of epidermal differentiation. Nucleic Acids Res. 2012;40(15):7190-206.
16 Chromatin immunoprecipitation on microarray analysis of Smad2/3 binding sites reveals roles of ETS1 and TFAP2A in transforming growth factor beta signaling. Mol Cell Biol. 2009;29(1):172-86.

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