Drug Transporter (DT) Information

General Information of DT
DT ID DTD0390
Gene Name SLC50A1
Protein Name Sugar transporter SWEET1
Gene ID
55974
UniProt ID
Q9BRV3
TCDB ID
2.A.123.1.4
3D Structure

Modelled DT Structure

Method: multi-sequence alignment based machine learning

Detail: Structure Info

Synonyms HsSWEET1; RAG1-activating protein 1; RAG1AP1; SCP; SLC50A1; SWEET1; Solute carrier family 50 member 1; Stromal cell protein; slv
DT Family Sweet, Pq-loop, Saliva, Mtn3 (SWEET) family ;
Tissue Specificity Ubiquitously expressed with highest expressionin oviduct, epididymis and intestine.
Function This transporter mediates sugar transport across membranes.
Endogenous Substrate(s) Sugars
Variability Data of This Drug Transporter (DT)

Regulatory Variability Data of This DT (VARIDT 4.0)

(α) Tissue Distribution Level of Sugar transporter SWEET1
Tissue Distribution Level (TD)

(β) Cell Distribution Level of Sugar transporter SWEET1
Cell Distribution Level (CD)

(γ) Organelle Distribution Level of Sugar transporter SWEET1
Organelle Distribution Level (Subc)

Regulatory Variability Data of This DT

(β) Post-translational Modification of Sugar transporter SWEET1
Post-translational Modification (PTM)

(γ) Transcriptional Regulation of Sugar transporter SWEET1
Transcriptional Regulation (TSR)

(δ) Epigenetic Regulation of Sugar transporter SWEET1
Epigenetic Regulation (EGR)

(ε) Exogenous Modulation of Sugar transporter SWEET1
Exogenous Modulation (EGM)

General Variability Data of This DT

(α) Genetic Polymorphisms of Sugar transporter SWEET1
Genetic Polymorphisms of This DT (GPD)

(β) Disease-specific Protein Abundances of Sugar transporter SWEET1
Disease-specific Protein Abundances of This DT (DPAD)

(γ) Species- and Tissue-specific DT Abundances
Species/Tissue-specific Protein Abundances of This DT (S/TPAD)

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