Detail Information of Transcriptional Regulations

General Information of Drug Transporter (DT)
DT ID	DTD0136 Transporter Info
Gene Name	SLC20A1
Transporter Name	Sodium-dependent phosphate transporter 1
Gene ID	6574
UniProt ID	Q8WUM9

Transcriptional Regulation of This DT (TSR)

TF Superclass1: Basic domains
Class1.1: Basic leucine zipper factors		Click to Show/Hide the Full List of 11 TF(s) Regulating This DT
ATF3		Click to Show/Hide to Show 1 Transcriptional Phenomena
Transcriptional Phenomenon1	Direct binding to SLC20A1 gene			[1]
TF Protein Name	Cyclic AMP-dependent transcription factor ATF-3		Transcription Factor Info
Tissue	Bone marrow; Colon; Liver
Related DT Changes	Direct regulating
Experiment method	TF-transporter regulations were collected from ChIP-Seq datasets.
Detailed Description	Cyclic AMP-dependent transcription factor ATF-3 (ATF3) can directly bind to the SLC20A1 gene, which in turn affects the expression or function of the drug transporter Sodium-dependent phosphate transporter 1.
BACH1		Click to Show/Hide to Show 1 Transcriptional Phenomena
Transcriptional Phenomenon1	Direct binding to SLC20A1 gene			[2]
TF Protein Name	Transcription regulator protein BACH1		Transcription Factor Info
Tissue	Embryo
Related DT Changes	Direct regulating
Experiment method	TF-transporter regulations were collected from ChIP-Seq datasets.
Detailed Description	Transcription regulator protein BACH1 (BACH1) can directly bind to the SLC20A1 gene, which in turn affects the expression or function of the drug transporter Sodium-dependent phosphate transporter 1.
BATF		Click to Show/Hide to Show 1 Transcriptional Phenomena
Transcriptional Phenomenon1	Direct binding to SLC20A1 gene			[3]
TF Protein Name	Basic leucine zipper transcriptional factor ATF-like		Transcription Factor Info
Tissue	Blood
Related DT Changes	Direct regulating
Experiment method	TF-transporter regulations were collected from ChIP-Seq datasets.
Detailed Description	Basic leucine zipper transcriptional factor ATF-like (BATF) can directly bind to the SLC20A1 gene, which in turn affects the expression or function of the drug transporter Sodium-dependent phosphate transporter 1.
CEBPA		Click to Show/Hide to Show 1 Transcriptional Phenomena
Transcriptional Phenomenon1	Direct binding to SLC20A1 gene			[4]
TF Protein Name	CCAAT/enhancer-binding protein alpha		Transcription Factor Info
Tissue	Blood; Liver
Related DT Changes	Direct regulating
Experiment method	TF-transporter regulations were collected from ChIP-Seq datasets.
Detailed Description	CCAAT/enhancer-binding protein alpha (CEBPA) can directly bind to the SLC20A1 gene, which in turn affects the expression or function of the drug transporter Sodium-dependent phosphate transporter 1.
CEBPB		Click to Show/Hide to Show 1 Transcriptional Phenomena
Transcriptional Phenomenon1	Direct binding to SLC20A1 gene			[3]
TF Protein Name	CCAAT/enhancer-binding protein beta		Transcription Factor Info
Tissue	Blood
Related DT Changes	Direct regulating
Experiment method	TF-transporter regulations were collected from ChIP-Seq datasets.
Detailed Description	CCAAT/enhancer-binding protein beta (CEBPB) can directly bind to the SLC20A1 gene, which in turn affects the expression or function of the drug transporter Sodium-dependent phosphate transporter 1.
CREB1		Click to Show/Hide to Show 1 Transcriptional Phenomena
Transcriptional Phenomenon1	Direct binding to SLC20A1 gene			[1]
TF Protein Name	Cyclic AMP-responsive element-binding protein 1		Transcription Factor Info
Tissue	Embryo; Liver; Lung; Uterus
Related DT Changes	Direct regulating
Experiment method	TF-transporter regulations were collected from ChIP-Seq datasets.
Detailed Description	Cyclic AMP-responsive element-binding protein 1 (CREB1) can directly bind to the SLC20A1 gene, which in turn affects the expression or function of the drug transporter Sodium-dependent phosphate transporter 1.
FOSL1		Click to Show/Hide to Show 1 Transcriptional Phenomena
Transcriptional Phenomenon1	Direct binding to SLC20A1 gene			[2]
TF Protein Name	Fos-related antigen 1		Transcription Factor Info
Tissue	Bone marrow; Breast; Colon
Related DT Changes	Direct regulating
Experiment method	TF-transporter regulations were collected from ChIP-Seq datasets.
Detailed Description	Fos-related antigen 1 (FOSL1) can directly bind to the SLC20A1 gene, which in turn affects the expression or function of the drug transporter Sodium-dependent phosphate transporter 1.
JUN		Click to Show/Hide to Show 1 Transcriptional Phenomena
Transcriptional Phenomenon1	Binding to SLC20A1 gene in Coronary artery disease condition			[5]
TF Protein Name	Transcription factor Jun		Transcription Factor Info
Studied Phenotype	.
Related DT Changes	Direct regulating
Detailed Description	Transcription factor Jun (JUN) has been reported to bind to the transcription of SLC20A1 gene in Coronary artery disease condition, which in turn affects the expression or function of the drug transporter Sodium-dependent phosphate transporter 1.
JUNB		Click to Show/Hide to Show 1 Transcriptional Phenomena
Transcriptional Phenomenon1	Direct binding to SLC20A1 gene			[3]
TF Protein Name	Transcription factor JunB		Transcription Factor Info
Tissue	Aorta
Related DT Changes	Direct regulating
Experiment method	TF-transporter regulations were collected from ChIP-Seq datasets.
Detailed Description	Transcription factor JunB (JUNB) can directly bind to the SLC20A1 gene, which in turn affects the expression or function of the drug transporter Sodium-dependent phosphate transporter 1.
JUND		Click to Show/Hide to Show 1 Transcriptional Phenomena
Transcriptional Phenomenon1	Direct binding to SLC20A1 gene			[1]
TF Protein Name	Transcription factor JunD		Transcription Factor Info
Tissue	Blood; Bone marrow; Brain; Breast; Cervix; Colon; Coronary artery; Embryo; Liver; Prostate
Related DT Changes	Direct regulating
Experiment method	TF-transporter regulations were collected from ChIP-Seq datasets.
Detailed Description	Transcription factor JunD (JUND) can directly bind to the SLC20A1 gene, which in turn affects the expression or function of the drug transporter Sodium-dependent phosphate transporter 1.
NFE2		Click to Show/Hide to Show 1 Transcriptional Phenomena
Transcriptional Phenomenon1	Direct binding to SLC20A1 gene			[4]
TF Protein Name	Transcription factor NF-E2 45 kDa subunit		Transcription Factor Info
Tissue	Blood; Liver
Related DT Changes	Direct regulating
Experiment method	TF-transporter regulations were collected from ChIP-Seq datasets.
Detailed Description	Transcription factor NF-E2 45 kDa subunit (NFE2) can directly bind to the SLC20A1 gene, which in turn affects the expression or function of the drug transporter Sodium-dependent phosphate transporter 1.
Class1.2: Basic helix-loop-helix factors		Click to Show/Hide the Full List of 14 TF(s) Regulating This DT
ARNT		Click to Show/Hide to Show 1 Transcriptional Phenomena
Transcriptional Phenomenon1	Direct binding to SLC20A1 gene			[3]
TF Protein Name	Aryl hydrocarbon receptor nuclear translocator		Transcription Factor Info
Tissue	Breast
Related DT Changes	Direct regulating
Experiment method	TF-transporter regulations were collected from ChIP-Seq datasets.
Detailed Description	Aryl hydrocarbon receptor nuclear translocator (ARNT) can directly bind to the SLC20A1 gene, which in turn affects the expression or function of the drug transporter Sodium-dependent phosphate transporter 1.
ARNTL		Click to Show/Hide to Show 1 Transcriptional Phenomena
Transcriptional Phenomenon1	Direct binding to SLC20A1 gene			[4]
TF Protein Name	Basic helix-loop-helix ARNT-like protein 1		Transcription Factor Info
Tissue	Bone; Colon
Related DT Changes	Direct regulating
Experiment method	TF-transporter regulations were collected from ChIP-Seq datasets.
Detailed Description	Basic helix-loop-helix ARNT-like protein 1 (ARNTL) can directly bind to the SLC20A1 gene, which in turn affects the expression or function of the drug transporter Sodium-dependent phosphate transporter 1.
BHLHE40		Click to Show/Hide to Show 1 Transcriptional Phenomena
Transcriptional Phenomenon1	Direct binding to SLC20A1 gene			[1]
TF Protein Name	Class E basic helix-loop-helix protein 40		Transcription Factor Info
Tissue	Blood; Bone marrow; Liver
Related DT Changes	Direct regulating
Experiment method	TF-transporter regulations were collected from ChIP-Seq datasets.
Detailed Description	Class E basic helix-loop-helix protein 40 (BHLHE40) can directly bind to the SLC20A1 gene, which in turn affects the expression or function of the drug transporter Sodium-dependent phosphate transporter 1.
HES1		Click to Show/Hide to Show 1 Transcriptional Phenomena
Transcriptional Phenomenon1	Direct binding to SLC20A1 gene			[4]
TF Protein Name	Transcription factor HES-1		Transcription Factor Info
Tissue	Colon; Liver
Related DT Changes	Direct regulating
Experiment method	TF-transporter regulations were collected from ChIP-Seq datasets.
Detailed Description	Transcription factor HES-1 (HES1) can directly bind to the SLC20A1 gene, which in turn affects the expression or function of the drug transporter Sodium-dependent phosphate transporter 1.
HEY1		Click to Show/Hide to Show 1 Transcriptional Phenomena
Transcriptional Phenomenon1	Direct binding to SLC20A1 gene			[2]
TF Protein Name	Hairy/enhancer-of-split related with YRPW motif protein 1		Transcription Factor Info
Tissue	Bone marrow
Related DT Changes	Direct regulating
Experiment method	TF-transporter regulations were collected from ChIP-Seq datasets.
Detailed Description	Hairy/enhancer-of-split related with YRPW motif protein 1 (HEY1) can directly bind to the SLC20A1 gene, which in turn affects the expression or function of the drug transporter Sodium-dependent phosphate transporter 1.
MITF		Click to Show/Hide to Show 2 Transcriptional Phenomena
Transcriptional Phenomenon1	Activation of SLC20A1 gene in melanoma condition			[6]
TF Protein Name	Microphthalmia-associated transcription factor		Transcription Factor Info
Studied Phenotype	.
Related DT Changes	Up regulating
Detailed Description	Microphthalmia-associated transcription factor (MITF) has been reported to activate the transcription of SLC20A1 gene in melanoma condition, which leads to an increased expression of the drug transporter Sodium-dependent phosphate transporter 1.
Transcriptional Phenomenon2	Direct binding to SLC20A1 gene			[4]
TF Protein Name	Microphthalmia-associated transcription factor		Transcription Factor Info
Tissue	Skin
Related DT Changes	Direct regulating
Experiment method	TF-transporter regulations were collected from ChIP-Seq datasets.
Detailed Description	Microphthalmia-associated transcription factor (MITF) can directly bind to the SLC20A1 gene, which in turn affects the expression or function of the drug transporter Sodium-dependent phosphate transporter 1.
MXI1		Click to Show/Hide to Show 1 Transcriptional Phenomena
Transcriptional Phenomenon1	Direct binding to SLC20A1 gene			[2]
TF Protein Name	Max-interacting protein 1		Transcription Factor Info
Tissue	Blood; Bone marrow; Brain; Cervix; Embryo; Liver; Lung
Related DT Changes	Direct regulating
Experiment method	TF-transporter regulations were collected from ChIP-Seq datasets.
Detailed Description	Max-interacting protein 1 (MXI1) can directly bind to the SLC20A1 gene, which in turn affects the expression or function of the drug transporter Sodium-dependent phosphate transporter 1.
MYC		Click to Show/Hide to Show 1 Transcriptional Phenomena
Transcriptional Phenomenon1	Binding to SLC20A1 gene in embryonic stem cells condition			[7]
TF Protein Name	Myc proto-oncogene protein		Transcription Factor Info
Related DT Changes	Direct regulating
Detailed Description	Myc proto-oncogene protein (MYC) has been reported to bind to the transcription of SLC20A1 gene in embryonic stem cells condition, which leads to an affected expression of the drug transporter Sodium-dependent phosphate transporter 1.
TCF12		Click to Show/Hide to Show 1 Transcriptional Phenomena
Transcriptional Phenomenon1	Direct binding to SLC20A1 gene			[3]
TF Protein Name	Transcription factor 12		Transcription Factor Info
Tissue	Blood; Brain; Breast; Embryo; Lung; Uterus
Related DT Changes	Direct regulating
Experiment method	TF-transporter regulations were collected from ChIP-Seq datasets.
Detailed Description	Transcription factor 12 (TCF12) can directly bind to the SLC20A1 gene, which in turn affects the expression or function of the drug transporter Sodium-dependent phosphate transporter 1.
TCF21		Click to Show/Hide to Show 1 Transcriptional Phenomena
Transcriptional Phenomenon1	Direct binding to SLC20A1 gene			[3]
TF Protein Name	Transcription factor 21		Transcription Factor Info
Tissue	Coronary artery
Related DT Changes	Direct regulating
Experiment method	TF-transporter regulations were collected from ChIP-Seq datasets.
Detailed Description	Transcription factor 21 (TCF21) can directly bind to the SLC20A1 gene, which in turn affects the expression or function of the drug transporter Sodium-dependent phosphate transporter 1.
TCF3		Click to Show/Hide to Show 1 Transcriptional Phenomena
Transcriptional Phenomenon1	Direct binding to SLC20A1 gene			[1]
TF Protein Name	Transcription factor E2-alpha		Transcription Factor Info
Tissue	Blood
Related DT Changes	Direct regulating
Experiment method	TF-transporter regulations were collected from ChIP-Seq datasets.
Detailed Description	Transcription factor E2-alpha (TCF3) can directly bind to the SLC20A1 gene, which in turn affects the expression or function of the drug transporter Sodium-dependent phosphate transporter 1.
TFAP4		Click to Show/Hide to Show 1 Transcriptional Phenomena
Transcriptional Phenomenon1	Direct binding to SLC20A1 gene			[2]
TF Protein Name	Transcription factor AP-4		Transcription Factor Info
Tissue	Blood
Related DT Changes	Direct regulating
Experiment method	TF-transporter regulations were collected from ChIP-Seq datasets.
Detailed Description	Transcription factor AP-4 (TFAP4) can directly bind to the SLC20A1 gene, which in turn affects the expression or function of the drug transporter Sodium-dependent phosphate transporter 1.
USF1		Click to Show/Hide to Show 1 Transcriptional Phenomena
Transcriptional Phenomenon1	Direct binding to SLC20A1 gene			[1]
TF Protein Name	Upstream stimulatory factor 1		Transcription Factor Info
Tissue	Blood; Bone marrow; Brain; Colon; Embryo; Liver; Lung; Uterus
Related DT Changes	Direct regulating
Experiment method	TF-transporter regulations were collected from ChIP-Seq datasets.
Detailed Description	Upstream stimulatory factor 1 (USF1) can directly bind to the SLC20A1 gene, which in turn affects the expression or function of the drug transporter Sodium-dependent phosphate transporter 1.
USF2		Click to Show/Hide to Show 1 Transcriptional Phenomena
Transcriptional Phenomenon1	Direct binding to SLC20A1 gene			[2]
TF Protein Name	Upstream stimulatory factor 2		Transcription Factor Info
Tissue	Blood; Cervix; Embryo; Liver
Related DT Changes	Direct regulating
Experiment method	TF-transporter regulations were collected from ChIP-Seq datasets.
Detailed Description	Upstream stimulatory factor 2 (USF2) can directly bind to the SLC20A1 gene, which in turn affects the expression or function of the drug transporter Sodium-dependent phosphate transporter 1.
Class1.3: Basic helix-span-helix factors		Click to Show/Hide the Full List of 2 TF(s) Regulating This DT
TFAP2A		Click to Show/Hide to Show 1 Transcriptional Phenomena
Transcriptional Phenomenon1	Direct binding to SLC20A1 gene			[2]
TF Protein Name	Transcription factor AP-2-alpha		Transcription Factor Info
Tissue	Breast; Cervix; Colon
Related DT Changes	Direct regulating
Experiment method	TF-transporter regulations were collected from ChIP-Seq datasets.
Detailed Description	Transcription factor AP-2-alpha (TFAP2A) can directly bind to the SLC20A1 gene, which in turn affects the expression or function of the drug transporter Sodium-dependent phosphate transporter 1.
TFAP2C		Click to Show/Hide to Show 2 Transcriptional Phenomena
Transcriptional Phenomenon1	Activation of SLC20A1 gene in breast cancer condition			[8]
TF Protein Name	Transcription factor AP-2 gamma		Transcription Factor Info
Studied Phenotype	.
Related DT Changes	Up regulating
Detailed Description	Transcription factor AP-2 gamma (TFAP2C) has been reported to activate the transcription of SLC20A1 gene in breast cancer condition, which leads to an increased expression of the drug transporter Sodium-dependent phosphate transporter 1.
Transcriptional Phenomenon2	Direct binding to SLC20A1 gene			[4]
TF Protein Name	Transcription factor AP-2 gamma		Transcription Factor Info
Tissue	Breast; Cervix; Skin
Related DT Changes	Direct regulating
Experiment method	TF-transporter regulations were collected from ChIP-Seq datasets.
Detailed Description	Transcription factor AP-2 gamma (TFAP2C) can directly bind to the SLC20A1 gene, which in turn affects the expression or function of the drug transporter Sodium-dependent phosphate transporter 1.
TF Superclass2: Zinc-coordinating DNA-binding domains
Class2.1: Nuclear receptors with C4 zinc fingers		Click to Show/Hide the Full List of 9 TF(s) Regulating This DT
AR		Click to Show/Hide to Show 1 Transcriptional Phenomena
Transcriptional Phenomenon1	Binding to SLC20A1 gene in prostate cancer condition			[9]
TF Protein Name	Androgen receptor		Transcription Factor Info
Studied Phenotype	.
Related DT Changes	Direct regulating
Detailed Description	Androgen receptor (AR) has been reported to bind to the transcription of SLC20A1 gene in prostate cancer condition, which leads to an affected expression of the drug transporter Sodium-dependent phosphate transporter 1.
ESR1		Click to Show/Hide to Show 1 Transcriptional Phenomena
Transcriptional Phenomenon1	Direct binding to SLC20A1 gene			[3]
TF Protein Name	Estrogen receptor		Transcription Factor Info
Tissue	Breast
Related DT Changes	Direct regulating
Experiment method	TF-transporter regulations were collected from ChIP-Seq datasets.
Detailed Description	Estrogen receptor (ESR1) can directly bind to the SLC20A1 gene, which in turn affects the expression or function of the drug transporter Sodium-dependent phosphate transporter 1.
ESRRA		Click to Show/Hide to Show 1 Transcriptional Phenomena
Transcriptional Phenomenon1	Direct binding to SLC20A1 gene			[4]
TF Protein Name	Steroid hormone receptor ERR1		Transcription Factor Info
Tissue	Colon; Liver
Related DT Changes	Direct regulating
Experiment method	TF-transporter regulations were collected from ChIP-Seq datasets.
Detailed Description	Steroid hormone receptor ERR1 (ESRRA) can directly bind to the SLC20A1 gene, which in turn affects the expression or function of the drug transporter Sodium-dependent phosphate transporter 1.
HNF4A		Click to Show/Hide to Show 1 Transcriptional Phenomena
Transcriptional Phenomenon1	Binding to SLC20A1 gene in health condition			[10]
TF Protein Name	Hepatocyte nuclear factor 4-alpha		Transcription Factor Info
Studied Phenotype	.
Related DT Changes	Direct regulating
Detailed Description	Hepatocyte nuclear factor 4-alpha (HNF4A) has been reported to bind to the transcription of SLC20A1 gene in health condition, which leads to an affected expression of the drug transporter Sodium-dependent phosphate transporter 1.
NR2F2		Click to Show/Hide to Show 1 Transcriptional Phenomena
Transcriptional Phenomenon1	Direct binding to SLC20A1 gene			[1]
TF Protein Name	COUP transcription factor 2		Transcription Factor Info
Tissue	Bone marrow; Breast; Liver
Related DT Changes	Direct regulating
Experiment method	TF-transporter regulations were collected from ChIP-Seq datasets.
Detailed Description	COUP transcription factor 2 (NR2F2) can directly bind to the SLC20A1 gene, which in turn affects the expression or function of the drug transporter Sodium-dependent phosphate transporter 1.
PPARD		Click to Show/Hide to Show 1 Transcriptional Phenomena
Transcriptional Phenomenon1	Repression of SLC20A1 gene in myofibroblasts condition			[11]
TF Protein Name	Peroxisome proliferator-activated receptor delta		Transcription Factor Info
Related DT Changes	Down regulating
Detailed Description	Peroxisome proliferator-activated receptor delta (PPARD) has been reported to repress the transcription of SLC20A1 gene in myofibroblasts condition, which leads to a decreased expression of the drug transporter Sodium-dependent phosphate transporter 1.
RXRA		Click to Show/Hide to Show 1 Transcriptional Phenomena
Transcriptional Phenomenon1	Direct binding to SLC20A1 gene			[1]
TF Protein Name	Retinoic acid receptor RXR-alpha		Transcription Factor Info
Tissue	Blood; Brain; Colon; Liver
Related DT Changes	Direct regulating
Experiment method	TF-transporter regulations were collected from ChIP-Seq datasets.
Detailed Description	Retinoic acid receptor RXR-alpha (RXRA) can directly bind to the SLC20A1 gene, which in turn affects the expression or function of the drug transporter Sodium-dependent phosphate transporter 1.
RXRG		Click to Show/Hide to Show 1 Transcriptional Phenomena
Transcriptional Phenomenon1	Direct binding to SLC20A1 gene			[2]
TF Protein Name	Retinoic acid receptor RXR-gamma		Transcription Factor Info
Tissue	Blood
Related DT Changes	Direct regulating
Experiment method	TF-transporter regulations were collected from ChIP-Seq datasets.
Detailed Description	Retinoic acid receptor RXR-gamma (RXRG) can directly bind to the SLC20A1 gene, which in turn affects the expression or function of the drug transporter Sodium-dependent phosphate transporter 1.
VDR		Click to Show/Hide to Show 2 Transcriptional Phenomena
Transcriptional Phenomenon1	Activation of SLC20A1 gene in monocytic leukemia condition			[12]
TF Protein Name	Vitamin D3 receptor		Transcription Factor Info
Affected Drug/Substrate	1a,25-dihydroxyvitamin D3
Studied Phenotype	.
Related DT Changes	Up regulating
Detailed Description	Vitamin D3 receptor (VDR) has been reported to activate the transcription of SLC20A1 gene in monocytic leukemia condition, which leads to an increased expression of the drug transporter Sodium-dependent phosphate transporter 1.
Transcriptional Phenomenon2	Binding to SLC20A1 gene in health condition			[13]
TF Protein Name	Vitamin D3 receptor		Transcription Factor Info
Studied Phenotype	.
Related DT Changes	Direct regulating
Detailed Description	Vitamin D3 receptor (VDR) has been reported to bind to the transcription of SLC20A1 gene in health condition, which leads to an affected expression of the drug transporter Sodium-dependent phosphate transporter 1.
Class2.2: Other C4 zinc finger-type factors		Click to Show/Hide the Full List of 2 TF(s) Regulating This DT
GATA1		Click to Show/Hide to Show 3 Transcriptional Phenomena
Transcriptional Phenomenon1	Binding to SLC20A1 gene in hematopoiesis condition			[14]
TF Protein Name	Erythroid transcription factor		Transcription Factor Info
Studied Phenotype	.
Related DT Changes	Direct regulating
Detailed Description	Erythroid transcription factor (GATA1) has been reported to bind to the transcription of SLC20A1 gene in hematopoiesis condition, which leads to an affected expression of the drug transporter Sodium-dependent phosphate transporter 1.
Transcriptional Phenomenon2	Binding to SLC20A1 gene in megakaryocytes condition			[15]
TF Protein Name	Erythroid transcription factor		Transcription Factor Info
Related DT Changes	Direct regulating
Detailed Description	Erythroid transcription factor (GATA1) has been reported to bind to the transcription of SLC20A1 gene in megakaryocytes condition, which leads to an affected expression of the drug transporter Sodium-dependent phosphate transporter 1.
Transcriptional Phenomenon3	Direct binding to SLC20A1 gene			[1]
TF Protein Name	Erythroid transcription factor		Transcription Factor Info
Tissue	Blood; Bone marrow; Liver
Related DT Changes	Direct regulating
Experiment method	TF-transporter regulations were collected from ChIP-Seq datasets.
Detailed Description	Erythroid transcription factor (GATA1) can directly bind to the SLC20A1 gene, which in turn affects the expression or function of the drug transporter Sodium-dependent phosphate transporter 1.
GATA2		Click to Show/Hide to Show 2 Transcriptional Phenomena
Transcriptional Phenomenon1	Binding to SLC20A1 gene in megakaryocytes condition			[15]
TF Protein Name	Endothelial transcription factor GATA-2		Transcription Factor Info
Related DT Changes	Direct regulating
Detailed Description	Endothelial transcription factor GATA-2 (GATA2) has been reported to bind to the transcription of SLC20A1 gene in megakaryocytes condition, which leads to an affected expression of the drug transporter Sodium-dependent phosphate transporter 1.
Transcriptional Phenomenon2	Activation of SLC20A1 gene in hematopoiesis condition			[14]
TF Protein Name	Endothelial transcription factor GATA-2		Transcription Factor Info
Studied Phenotype	.
Related DT Changes	Up regulating
Detailed Description	Endothelial transcription factor GATA-2 (GATA2) has been reported to activate the transcription of SLC20A1 gene in hematopoiesis condition, which leads to an increased expression of the drug transporter Sodium-dependent phosphate transporter 1.
Class2.3: C2H2 zinc finger factors		Click to Show/Hide the Full List of 15 TF(s) Regulating This DT
BCL6		Click to Show/Hide to Show 2 Transcriptional Phenomena
Transcriptional Phenomenon1	Activation of SLC20A1 gene in health condition			[16]
TF Protein Name	B-cell lymphoma 6 protein		Transcription Factor Info
Studied Phenotype	.
Related DT Changes	Up regulating
Detailed Description	B-cell lymphoma 6 protein (BCL6) has been reported to activate the transcription of SLC20A1 gene in health condition, which leads to an increased expression of the drug transporter Sodium-dependent phosphate transporter 1.
Transcriptional Phenomenon2	Direct binding to SLC20A1 gene			[1]
TF Protein Name	B-cell lymphoma 6 protein		Transcription Factor Info
Tissue	Tonsil
Related DT Changes	Direct regulating
Experiment method	TF-transporter regulations were collected from ChIP-Seq datasets.
Detailed Description	B-cell lymphoma 6 protein (BCL6) can directly bind to the SLC20A1 gene, which in turn affects the expression or function of the drug transporter Sodium-dependent phosphate transporter 1.
CTCF		Click to Show/Hide to Show 1 Transcriptional Phenomena
Transcriptional Phenomenon1	Direct binding to SLC20A1 gene			[2]
TF Protein Name	Transcriptional repressor CTCF		Transcription Factor Info
Tissue	Brain
Related DT Changes	Direct regulating
Experiment method	TF-transporter regulations were collected from ChIP-Seq datasets.
Detailed Description	Transcriptional repressor CTCF (CTCF) can directly bind to the SLC20A1 gene, which in turn affects the expression or function of the drug transporter Sodium-dependent phosphate transporter 1.
CTCFL		Click to Show/Hide to Show 1 Transcriptional Phenomena
Transcriptional Phenomenon1	Direct binding to SLC20A1 gene			[2]
TF Protein Name	Transcriptional repressor CTCFL		Transcription Factor Info
Tissue	Bone marrow
Related DT Changes	Direct regulating
Experiment method	TF-transporter regulations were collected from ChIP-Seq datasets.
Detailed Description	Transcriptional repressor CTCFL (CTCFL) can directly bind to the SLC20A1 gene, which in turn affects the expression or function of the drug transporter Sodium-dependent phosphate transporter 1.
KLF1		Click to Show/Hide to Show 1 Transcriptional Phenomena
Transcriptional Phenomenon1	Direct binding to SLC20A1 gene			[2]
TF Protein Name	Krueppel-like factor 1		Transcription Factor Info
Tissue	Blood
Related DT Changes	Direct regulating
Experiment method	TF-transporter regulations were collected from ChIP-Seq datasets.
Detailed Description	Krueppel-like factor 1 (KLF1) can directly bind to the SLC20A1 gene, which in turn affects the expression or function of the drug transporter Sodium-dependent phosphate transporter 1.
KLF4		Click to Show/Hide to Show 1 Transcriptional Phenomena
Transcriptional Phenomenon1	Direct binding to SLC20A1 gene			[4]
TF Protein Name	Krueppel-like factor 4		Transcription Factor Info
Tissue	Breast; Foreskin; Pancreatic ductal
Related DT Changes	Direct regulating
Experiment method	TF-transporter regulations were collected from ChIP-Seq datasets.
Detailed Description	Krueppel-like factor 4 (KLF4) can directly bind to the SLC20A1 gene, which in turn affects the expression or function of the drug transporter Sodium-dependent phosphate transporter 1.
KLF5		Click to Show/Hide to Show 1 Transcriptional Phenomena
Transcriptional Phenomenon1	Direct binding to SLC20A1 gene			[4]
TF Protein Name	Krueppel-like factor 5		Transcription Factor Info
Tissue	Colon; Pancreatic ductal; Stomach
Related DT Changes	Direct regulating
Experiment method	TF-transporter regulations were collected from ChIP-Seq datasets.
Detailed Description	Krueppel-like factor 5 (KLF5) can directly bind to the SLC20A1 gene, which in turn affects the expression or function of the drug transporter Sodium-dependent phosphate transporter 1.
MAZ		Click to Show/Hide to Show 1 Transcriptional Phenomena
Transcriptional Phenomenon1	Direct binding to SLC20A1 gene			[3]
TF Protein Name	Myc-associated zinc finger protein		Transcription Factor Info
Tissue	Blood; Bone marrow; Cervix; Liver; Lung
Related DT Changes	Direct regulating
Experiment method	TF-transporter regulations were collected from ChIP-Seq datasets.
Detailed Description	Myc-associated zinc finger protein (MAZ) can directly bind to the SLC20A1 gene, which in turn affects the expression or function of the drug transporter Sodium-dependent phosphate transporter 1.
MECOM		Click to Show/Hide to Show 1 Transcriptional Phenomena
Transcriptional Phenomenon1	Direct binding to SLC20A1 gene			[3]
TF Protein Name	Histone-lysine N-methyltransferase MECOM		Transcription Factor Info
Tissue	Colon
Related DT Changes	Direct regulating
Experiment method	TF-transporter regulations were collected from ChIP-Seq datasets.
Detailed Description	Histone-lysine N-methyltransferase MECOM (MECOM) can directly bind to the SLC20A1 gene, which in turn affects the expression or function of the drug transporter Sodium-dependent phosphate transporter 1.
SALL4		Click to Show/Hide to Show 1 Transcriptional Phenomena
Transcriptional Phenomenon1	Binding to SLC20A1 gene in health condition			[17]
TF Protein Name	Sal-like protein 4		Transcription Factor Info
Studied Phenotype	.
Related DT Changes	Direct regulating
Detailed Description	Sal-like protein 4 (SALL4) has been reported to bind to the transcription of SLC20A1 gene in health condition, which leads to an affected expression of the drug transporter Sodium-dependent phosphate transporter 1.
SP1		Click to Show/Hide to Show 2 Transcriptional Phenomena
Transcriptional Phenomenon1	Activation of SLC20A1 gene in osteosarcoma condition			[18]
TF Protein Name	Transcription factor Sp1		Transcription Factor Info
Studied Phenotype	Osteosarcoma [ICD11: 2B51]
Tissue	Bone
Related DT Changes	Up regulating
Experimental Material	Human osteosarcoma cells (Saos-2)
Detailed Description	Transcription factor Sp1 (SP1) has been reported to activate the transcription of SLC20A1 gene in osteosarcoma condition, which leads to an increased expression of the drug transporter Sodium-dependent phosphate transporter 1.
Transcriptional Phenomenon2	Direct binding to SLC20A1 gene			[2]
TF Protein Name	Transcription factor Sp1		Transcription Factor Info
Tissue	Blood; Colon; Embryo; Liver; Lung
Related DT Changes	Direct regulating
Experiment method	TF-transporter regulations were collected from ChIP-Seq datasets.
Detailed Description	Transcription factor Sp1 (SP1) can directly bind to the SLC20A1 gene, which in turn affects the expression or function of the drug transporter Sodium-dependent phosphate transporter 1.
SP3		Click to Show/Hide to Show 1 Transcriptional Phenomena
Transcriptional Phenomenon1	Activation of SLC20A1 gene in osteosarcoma condition			[18]
TF Protein Name	Transcription factor Sp3		Transcription Factor Info
Studied Phenotype	Osteosarcoma [ICD11: 2B51]
Tissue	Bone
Related DT Changes	Up regulating
Experimental Material	Human osteosarcoma cells (Saos-2)
Detailed Description	Transcription factor Sp3 (SP3) has been reported to activate the transcription of SLC20A1 gene in osteosarcoma condition, which leads to an increased expression of the drug transporter Sodium-dependent phosphate transporter 1.
YY1		Click to Show/Hide to Show 1 Transcriptional Phenomena
Transcriptional Phenomenon1	Direct binding to SLC20A1 gene			[4]
TF Protein Name	Transcriptional repressor protein YY1		Transcription Factor Info
Tissue	Blood; Bone marrow; Brain; Colon; Embryo; Liver; Lung; Uterus
Related DT Changes	Direct regulating
Experiment method	TF-transporter regulations were collected from ChIP-Seq datasets.
Detailed Description	Transcriptional repressor protein YY1 (YY1) can directly bind to the SLC20A1 gene, which in turn affects the expression or function of the drug transporter Sodium-dependent phosphate transporter 1.
ZBTB7A		Click to Show/Hide to Show 1 Transcriptional Phenomena
Transcriptional Phenomenon1	Direct binding to SLC20A1 gene			[3]
TF Protein Name	Zinc finger and BTB domain-containing protein 7A		Transcription Factor Info
Tissue	Bone marrow; Uterus
Related DT Changes	Direct regulating
Experiment method	TF-transporter regulations were collected from ChIP-Seq datasets.
Detailed Description	Zinc finger and BTB domain-containing protein 7A (ZBTB7A) can directly bind to the SLC20A1 gene, which in turn affects the expression or function of the drug transporter Sodium-dependent phosphate transporter 1.
ZNF263		Click to Show/Hide to Show 1 Transcriptional Phenomena
Transcriptional Phenomenon1	Direct binding to SLC20A1 gene			[3]
TF Protein Name	Zinc finger protein 263		Transcription Factor Info
Tissue	Bone marrow; Kidney
Related DT Changes	Direct regulating
Experiment method	TF-transporter regulations were collected from ChIP-Seq datasets.
Detailed Description	Zinc finger protein 263 (ZNF263) can directly bind to the SLC20A1 gene, which in turn affects the expression or function of the drug transporter Sodium-dependent phosphate transporter 1.
ZNF384		Click to Show/Hide to Show 1 Transcriptional Phenomena
Transcriptional Phenomenon1	Direct binding to SLC20A1 gene			[1]
TF Protein Name	Zinc finger protein 384		Transcription Factor Info
Tissue	Bone marrow
Related DT Changes	Direct regulating
Experiment method	TF-transporter regulations were collected from ChIP-Seq datasets.
Detailed Description	Zinc finger protein 384 (ZNF384) can directly bind to the SLC20A1 gene, which in turn affects the expression or function of the drug transporter Sodium-dependent phosphate transporter 1.
Class2.9: C2CH THAP-type zinc finger factors		Click to Show/Hide the Full List of 1 TF(s) Regulating This DT
THAP1		Click to Show/Hide to Show 1 Transcriptional Phenomena
Transcriptional Phenomenon1	Direct binding to SLC20A1 gene			[4]
TF Protein Name	THAP domain-containing protein 1		Transcription Factor Info
Tissue	Bone marrow
Related DT Changes	Direct regulating
Experiment method	TF-transporter regulations were collected from ChIP-Seq datasets.
Detailed Description	THAP domain-containing protein 1 (THAP1) can directly bind to the SLC20A1 gene, which in turn affects the expression or function of the drug transporter Sodium-dependent phosphate transporter 1.
TF Superclass3: Helix-turn-helix domains
Class3.1: Homeo domain factors		Click to Show/Hide the Full List of 1 TF(s) Regulating This DT
POU2F1		Click to Show/Hide to Show 1 Transcriptional Phenomena
Transcriptional Phenomenon1	Direct binding to SLC20A1 gene			[2]
TF Protein Name	POU domain, class 2, transcription factor 1		Transcription Factor Info
Tissue	Blood
Related DT Changes	Direct regulating
Experiment method	TF-transporter regulations were collected from ChIP-Seq datasets.
Detailed Description	POU domain, class 2, transcription factor 1 (POU2F1) can directly bind to the SLC20A1 gene, which in turn affects the expression or function of the drug transporter Sodium-dependent phosphate transporter 1.
Class3.3: Fork head / winged helix factors		Click to Show/Hide the Full List of 7 TF(s) Regulating This DT
E2F1		Click to Show/Hide to Show 2 Transcriptional Phenomena
Transcriptional Phenomenon1	Binding to SLC20A1 gene in MCF7 condition			[19]
TF Protein Name	Transcription factor E2F1		Transcription Factor Info
Related DT Changes	Direct regulating
Detailed Description	Transcription factor E2F1 (E2F1) has been reported to bind to the transcription of SLC20A1 gene in MCF7 condition, which leads to an affected expression of the drug transporter Sodium-dependent phosphate transporter 1.
Transcriptional Phenomenon2	Direct binding to SLC20A1 gene			[3]
TF Protein Name	Transcription factor E2F1		Transcription Factor Info
Tissue	Mesenchymal
Related DT Changes	Direct regulating
Experiment method	TF-transporter regulations were collected from ChIP-Seq datasets.
Detailed Description	Transcription factor E2F1 (E2F1) can directly bind to the SLC20A1 gene, which in turn affects the expression or function of the drug transporter Sodium-dependent phosphate transporter 1.
E2F4		Click to Show/Hide to Show 1 Transcriptional Phenomena
Transcriptional Phenomenon1	Binding to SLC20A1 gene in health condition			[20]
TF Protein Name	Transcription factor E2F4		Transcription Factor Info
Studied Phenotype	.
Related DT Changes	Direct regulating
Detailed Description	Transcription factor E2F4 (E2F4) has been reported to bind to the transcription of SLC20A1 gene in health condition, which leads to an affected expression of the drug transporter Sodium-dependent phosphate transporter 1.
E2F6		Click to Show/Hide to Show 1 Transcriptional Phenomena
Transcriptional Phenomenon1	Direct binding to SLC20A1 gene			[1]
TF Protein Name	Transcription factor E2F6		Transcription Factor Info
Tissue	Bone marrow; Embryo; Lung
Related DT Changes	Direct regulating
Experiment method	TF-transporter regulations were collected from ChIP-Seq datasets.
Detailed Description	Transcription factor E2F6 (E2F6) can directly bind to the SLC20A1 gene, which in turn affects the expression or function of the drug transporter Sodium-dependent phosphate transporter 1.
FOXA1		Click to Show/Hide to Show 1 Transcriptional Phenomena
Transcriptional Phenomenon1	Direct binding to SLC20A1 gene			[3]
TF Protein Name	Hepatocyte nuclear factor 3-alpha		Transcription Factor Info
Tissue	Breast; Liver; Lung; Pancreatic ductal; Prostate
Related DT Changes	Direct regulating
Experiment method	TF-transporter regulations were collected from ChIP-Seq datasets.
Detailed Description	Hepatocyte nuclear factor 3-alpha (FOXA1) can directly bind to the SLC20A1 gene, which in turn affects the expression or function of the drug transporter Sodium-dependent phosphate transporter 1.
FOXA2		Click to Show/Hide to Show 1 Transcriptional Phenomena
Transcriptional Phenomenon1	Direct binding to SLC20A1 gene			[1]
TF Protein Name	Hepatocyte nuclear factor 3-beta		Transcription Factor Info
Tissue	Colon
Related DT Changes	Direct regulating
Experiment method	TF-transporter regulations were collected from ChIP-Seq datasets.
Detailed Description	Hepatocyte nuclear factor 3-beta (FOXA2) can directly bind to the SLC20A1 gene, which in turn affects the expression or function of the drug transporter Sodium-dependent phosphate transporter 1.
FOXO3		Click to Show/Hide to Show 1 Transcriptional Phenomena
Transcriptional Phenomenon1	Direct binding to SLC20A1 gene			[2]
TF Protein Name	Forkhead box protein O3		Transcription Factor Info
Tissue	Colon; Liver
Related DT Changes	Direct regulating
Experiment method	TF-transporter regulations were collected from ChIP-Seq datasets.
Detailed Description	Forkhead box protein O3 (FOXO3) can directly bind to the SLC20A1 gene, which in turn affects the expression or function of the drug transporter Sodium-dependent phosphate transporter 1.
FOXP1		Click to Show/Hide to Show 1 Transcriptional Phenomena
Transcriptional Phenomenon1	Direct binding to SLC20A1 gene			[3]
TF Protein Name	Forkhead box protein P1		Transcription Factor Info
Tissue	Colon; Embryo; Prostate
Related DT Changes	Direct regulating
Experiment method	TF-transporter regulations were collected from ChIP-Seq datasets.
Detailed Description	Forkhead box protein P1 (FOXP1) can directly bind to the SLC20A1 gene, which in turn affects the expression or function of the drug transporter Sodium-dependent phosphate transporter 1.
Class3.5: Tryptophan cluster factors		Click to Show/Hide the Full List of 7 TF(s) Regulating This DT
ERG		Click to Show/Hide to Show 1 Transcriptional Phenomena
Transcriptional Phenomenon1	Direct binding to SLC20A1 gene			[2]
TF Protein Name	Transcriptional regulator ERG		Transcription Factor Info
Tissue	Aorta
Related DT Changes	Direct regulating
Experiment method	TF-transporter regulations were collected from ChIP-Seq datasets.
Detailed Description	Transcriptional regulator ERG (ERG) can directly bind to the SLC20A1 gene, which in turn affects the expression or function of the drug transporter Sodium-dependent phosphate transporter 1.
ETS1		Click to Show/Hide to Show 1 Transcriptional Phenomena
Transcriptional Phenomenon1	Direct binding to SLC20A1 gene			[4]
TF Protein Name	Protein C-ets-1		Transcription Factor Info
Tissue	Blood; Bone; Bone marrow; Kidney; Lung; Prostate; Vein
Related DT Changes	Direct regulating
Experiment method	TF-transporter regulations were collected from ChIP-Seq datasets.
Detailed Description	Protein C-ets-1 (ETS1) can directly bind to the SLC20A1 gene, which in turn affects the expression or function of the drug transporter Sodium-dependent phosphate transporter 1.
ETS2		Click to Show/Hide to Show 1 Transcriptional Phenomena
Transcriptional Phenomenon1	Direct binding to SLC20A1 gene			[2]
TF Protein Name	Protein C-ets-2		Transcription Factor Info
Tissue	Colon
Related DT Changes	Direct regulating
Experiment method	TF-transporter regulations were collected from ChIP-Seq datasets.
Detailed Description	Protein C-ets-2 (ETS2) can directly bind to the SLC20A1 gene, which in turn affects the expression or function of the drug transporter Sodium-dependent phosphate transporter 1.
FLI1		Click to Show/Hide to Show 1 Transcriptional Phenomena
Transcriptional Phenomenon1	Direct binding to SLC20A1 gene			[4]
TF Protein Name	Friend leukemia integration 1 transcription factor		Transcription Factor Info
Tissue	Blood; Mesenchymal; Vein
Related DT Changes	Direct regulating
Experiment method	TF-transporter regulations were collected from ChIP-Seq datasets.
Detailed Description	Friend leukemia integration 1 transcription factor (FLI1) can directly bind to the SLC20A1 gene, which in turn affects the expression or function of the drug transporter Sodium-dependent phosphate transporter 1.
IRF1		Click to Show/Hide to Show 1 Transcriptional Phenomena
Transcriptional Phenomenon1	Direct binding to SLC20A1 gene			[4]
TF Protein Name	Interferon regulatory factor 1		Transcription Factor Info
Tissue	Blood; Bone marrow; Pancreatic ductal
Related DT Changes	Direct regulating
Experiment method	TF-transporter regulations were collected from ChIP-Seq datasets.
Detailed Description	Interferon regulatory factor 1 (IRF1) can directly bind to the SLC20A1 gene, which in turn affects the expression or function of the drug transporter Sodium-dependent phosphate transporter 1.
MYB		Click to Show/Hide to Show 1 Transcriptional Phenomena
Transcriptional Phenomenon1	Direct binding to SLC20A1 gene			[3]
TF Protein Name	Transcriptional activator Myb		Transcription Factor Info
Tissue	Blood
Related DT Changes	Direct regulating
Experiment method	TF-transporter regulations were collected from ChIP-Seq datasets.
Detailed Description	Transcriptional activator Myb (MYB) can directly bind to the SLC20A1 gene, which in turn affects the expression or function of the drug transporter Sodium-dependent phosphate transporter 1.
SPI1		Click to Show/Hide to Show 1 Transcriptional Phenomena
Transcriptional Phenomenon1	Direct binding to SLC20A1 gene			[4]
TF Protein Name	Transcription factor PU.1		Transcription Factor Info
Tissue	Adrenal gland; Blood; Bone marrow; Brain; Breast; Embryo; Foreskin; Heart; Intestine; Kidney; Lung; Muscle; Penis; Placenta; Renal cortex; Renal pelvis; Skin; Spinal cord; Stomach; Testes; Umbilical cord blood
Related DT Changes	Direct regulating
Experiment method	TF-transporter regulations were collected from ChIP-Seq datasets.
Detailed Description	Transcription factor PU.1 (SPI1) can directly bind to the SLC20A1 gene, which in turn affects the expression or function of the drug transporter Sodium-dependent phosphate transporter 1.
Class3.7: ARID domain factors		Click to Show/Hide the Full List of 2 TF(s) Regulating This DT
ARID3A		Click to Show/Hide to Show 1 Transcriptional Phenomena
Transcriptional Phenomenon1	Direct binding to SLC20A1 gene			[1]
TF Protein Name	AT-rich interactive domain-containing protein 3A		Transcription Factor Info
Tissue	Liver
Related DT Changes	Direct regulating
Experiment method	TF-transporter regulations were collected from ChIP-Seq datasets.
Detailed Description	AT-rich interactive domain-containing protein 3A (ARID3A) can directly bind to the SLC20A1 gene, which in turn affects the expression or function of the drug transporter Sodium-dependent phosphate transporter 1.
KDM5B		Click to Show/Hide to Show 1 Transcriptional Phenomena
Transcriptional Phenomenon1	Direct binding to SLC20A1 gene			[1]
TF Protein Name	Lysine-specific demethylase 5B		Transcription Factor Info
Tissue	Bone marrow; Breast
Related DT Changes	Direct regulating
Experiment method	TF-transporter regulations were collected from ChIP-Seq datasets.
Detailed Description	Lysine-specific demethylase 5B (KDM5B) can directly bind to the SLC20A1 gene, which in turn affects the expression or function of the drug transporter Sodium-dependent phosphate transporter 1.
TF Superclass4: Other all-alpha-helical DNA-binding domains
Class4.2: Heteromeric CCAAT-binding factors		Click to Show/Hide the Full List of 2 TF(s) Regulating This DT
NFYA		Click to Show/Hide to Show 1 Transcriptional Phenomena
Transcriptional Phenomenon1	Direct binding to SLC20A1 gene			[4]
TF Protein Name	Nuclear transcription factor Y subunit alpha		Transcription Factor Info
Tissue	Bone marrow; Cervix
Related DT Changes	Direct regulating
Experiment method	TF-transporter regulations were collected from ChIP-Seq datasets.
Detailed Description	Nuclear transcription factor Y subunit alpha (NFYA) can directly bind to the SLC20A1 gene, which in turn affects the expression or function of the drug transporter Sodium-dependent phosphate transporter 1.
NFYB		Click to Show/Hide to Show 1 Transcriptional Phenomena
Transcriptional Phenomenon1	Direct binding to SLC20A1 gene			[3]
TF Protein Name	Nuclear transcription factor Y subunit beta		Transcription Factor Info
Tissue	Blood; Bone marrow; Cervix
Related DT Changes	Direct regulating
Experiment method	TF-transporter regulations were collected from ChIP-Seq datasets.
Detailed Description	Nuclear transcription factor Y subunit beta (NFYB) can directly bind to the SLC20A1 gene, which in turn affects the expression or function of the drug transporter Sodium-dependent phosphate transporter 1.
TF Superclass5: alpha-Helices exposed by beta-structures
Class5.1: MADS box factors		Click to Show/Hide the Full List of 1 TF(s) Regulating This DT
SRF		Click to Show/Hide to Show 1 Transcriptional Phenomena
Transcriptional Phenomenon1	Direct binding to SLC20A1 gene			[1]
TF Protein Name	Serum response factor		Transcription Factor Info
Tissue	Blood; Embryo; Uterus
Related DT Changes	Direct regulating
Experiment method	TF-transporter regulations were collected from ChIP-Seq datasets.
Detailed Description	Serum response factor (SRF) can directly bind to the SLC20A1 gene, which in turn affects the expression or function of the drug transporter Sodium-dependent phosphate transporter 1.
TF Superclass6: Immunoglobulin fold
Class6.1: Rel homology region factors		Click to Show/Hide the Full List of 1 TF(s) Regulating This DT
EBF1		Click to Show/Hide to Show 1 Transcriptional Phenomena
Transcriptional Phenomenon1	Direct binding to SLC20A1 gene			[1]
TF Protein Name	Transcription factor COE1		Transcription Factor Info
Tissue	Blood
Related DT Changes	Direct regulating
Experiment method	TF-transporter regulations were collected from ChIP-Seq datasets.
Detailed Description	Transcription factor COE1 (EBF1) can directly bind to the SLC20A1 gene, which in turn affects the expression or function of the drug transporter Sodium-dependent phosphate transporter 1.
Class6.3: p53 domain factors		Click to Show/Hide the Full List of 1 TF(s) Regulating This DT
TP63		Click to Show/Hide to Show 2 Transcriptional Phenomena
Transcriptional Phenomenon1	Binding to SLC20A1 gene in health condition			[21]
TF Protein Name	Tumor protein 63		Transcription Factor Info
Studied Phenotype	.
Related DT Changes	Direct regulating
Detailed Description	Tumor protein 63 (TP63) has been reported to bind to the transcription of SLC20A1 gene in health condition, which leads to an affected expression of the drug transporter Sodium-dependent phosphate transporter 1.
Transcriptional Phenomenon2	Direct binding to SLC20A1 gene			[3]
TF Protein Name	Tumor protein 63		Transcription Factor Info
Tissue	Lung
Related DT Changes	Direct regulating
Experiment method	TF-transporter regulations were collected from ChIP-Seq datasets.
Detailed Description	Tumor protein 63 (TP63) can directly bind to the SLC20A1 gene, which in turn affects the expression or function of the drug transporter Sodium-dependent phosphate transporter 1.
Class6.4: Runt domain factors		Click to Show/Hide the Full List of 1 TF(s) Regulating This DT
RUNX2		Click to Show/Hide to Show 1 Transcriptional Phenomena
Transcriptional Phenomenon1	Activation of SLC20A1 gene in prostate cancer condition			[22]
TF Protein Name	Runt-related transcription factor 2		Transcription Factor Info
Studied Phenotype	.
Related DT Changes	Up regulating
Detailed Description	Runt-related transcription factor 2 (RUNX2) has been reported to activate the transcription of SLC20A1 gene in prostate cancer condition, which leads to an increased expression of the drug transporter Sodium-dependent phosphate transporter 1.
Class6.7: Grainyhead domain factors		Click to Show/Hide the Full List of 1 TF(s) Regulating This DT
GRHL2		Click to Show/Hide to Show 1 Transcriptional Phenomena
Transcriptional Phenomenon1	Direct binding to SLC20A1 gene			[2]
TF Protein Name	Grainyhead-like protein 2 homolog		Transcription Factor Info
Tissue	Breast; Bronchus; Ovary; Prostate
Related DT Changes	Direct regulating
Experiment method	TF-transporter regulations were collected from ChIP-Seq datasets.
Detailed Description	Grainyhead-like protein 2 homolog (GRHL2) can directly bind to the SLC20A1 gene, which in turn affects the expression or function of the drug transporter Sodium-dependent phosphate transporter 1.
TF Superclass7: beta-Hairpin exposed by an alpha/beta-scaffold
Class7.1: SMAD/NF-1 DNA-binding domain factors		Click to Show/Hide the Full List of 3 TF(s) Regulating This DT
NFIC		Click to Show/Hide to Show 1 Transcriptional Phenomena
Transcriptional Phenomenon1	Direct binding to SLC20A1 gene			[4]
TF Protein Name	Nuclear factor 1 C-type		Transcription Factor Info
Tissue	Blood; Brain; Liver; Uterus
Related DT Changes	Direct regulating
Experiment method	TF-transporter regulations were collected from ChIP-Seq datasets.
Detailed Description	Nuclear factor 1 C-type (NFIC) can directly bind to the SLC20A1 gene, which in turn affects the expression or function of the drug transporter Sodium-dependent phosphate transporter 1.
SMAD3		Click to Show/Hide to Show 2 Transcriptional Phenomena
Transcriptional Phenomenon1	Activation of SLC20A1 gene in human embryonic stem cells (hESCs) condition			[23]
TF Protein Name	Mothers against decapentaplegic homolog 3		Transcription Factor Info
Studied Phenotype	.
Related DT Changes	Up regulating
Detailed Description	Mothers against decapentaplegic homolog 3 (SMAD3) has been reported to activate the transcription of SLC20A1 gene in human embryonic stem cells (hESCs) condition, which leads to an increased expression of the drug transporter Sodium-dependent phosphate transporter 1.
Transcriptional Phenomenon2	Binding to SLC20A1 gene in HaCaT keratinocytes condition			[24]
TF Protein Name	Mothers against decapentaplegic homolog 3		Transcription Factor Info
Related DT Changes	Direct regulating
Detailed Description	Mothers against decapentaplegic homolog 3 (SMAD3) has been reported to bind to the transcription of SLC20A1 gene in HaCaT keratinocytes condition, which leads to an affected expression of the drug transporter Sodium-dependent phosphate transporter 1.
SMAD4		Click to Show/Hide to Show 2 Transcriptional Phenomena
Transcriptional Phenomenon1	Activation of SLC20A1 gene in epithelial ovarian cancer condition			[25]
TF Protein Name	Mothers against decapentaplegic homolog 4		Transcription Factor Info
Studied Phenotype	.
Related DT Changes	Up regulating
Detailed Description	Mothers against decapentaplegic homolog 4 (SMAD4) has been reported to activate the transcription of SLC20A1 gene in epithelial ovarian cancer condition, which leads to an increased expression of the drug transporter Sodium-dependent phosphate transporter 1.
Transcriptional Phenomenon2	Activation of SLC20A1 gene in hESCs			[23]
TF Protein Name	Mothers against decapentaplegic homolog 4		Transcription Factor Info
Studied Phenotype	.
Related DT Changes	Up regulating
Detailed Description	Mothers against decapentaplegic homolog 4 (SMAD4) has been reported to activate the transcription of SLC20A1 gene in human embryonic stem cells (hESCs), which leads to an increased expression of the drug transporter Sodium-dependent phosphate transporter 1.
TF Superclass8: beta-Sheet binding to DNA
Class8.1: TATA-binding proteins		Click to Show/Hide the Full List of 1 TF(s) Regulating This DT
TBP		Click to Show/Hide to Show 1 Transcriptional Phenomena
Transcriptional Phenomenon1	Direct binding to SLC20A1 gene			[2]
TF Protein Name	TATA-box-binding protein		Transcription Factor Info
Tissue	Blood; Bone marrow; Cervix; Embryo; Liver
Related DT Changes	Direct regulating
Experiment method	TF-transporter regulations were collected from ChIP-Seq datasets.
Detailed Description	TATA-box-binding protein (TBP) can directly bind to the SLC20A1 gene, which in turn affects the expression or function of the drug transporter Sodium-dependent phosphate transporter 1.
TF Superclass10: Yet undefined DNA-binding domains
Class10.1: Other factors		Click to Show/Hide the Full List of 1 TF(s) Regulating This DT
GTF2B		Click to Show/Hide to Show 1 Transcriptional Phenomena
Transcriptional Phenomenon1	Direct binding to SLC20A1 gene			[1]
TF Protein Name	Transcription initiation factor IIB		Transcription Factor Info
Tissue	Bone marrow; Cervix; Lung
Related DT Changes	Direct regulating
Experiment method	TF-transporter regulations were collected from ChIP-Seq datasets.
Detailed Description	Transcription initiation factor IIB (GTF2B) can directly bind to the SLC20A1 gene, which in turn affects the expression or function of the drug transporter Sodium-dependent phosphate transporter 1.

References
1	hTFtarget: A Comprehensive Database for Regulations of Human Transcription Factors and Their Targets. Genomics Proteomics Bioinformatics. 2020 Apr;18(2):120-308. (ID:ENSG00000144136)
2	NCBI GEO: archive for functional genomics data sets--update. Nucleic Acids Res. 2013 Jan;41(D1):D991-5.
3	The Encyclopedia of DNA elements (ENCODE): data portal update. Nucleic Acids Res. 2018 Jan 4;46(D1):D794-D801
4	Closure of the NCBI SRA and implications for the long-term future of genomics data storage. Genome Biol. 2011;12(3):402.
5	Characterization of TCF21 Downstream Target Regions Identifies a Transcriptional Network Linking Multiple Independent Coronary Artery Disease Loci. PLoS Genet. 2015;11(5):e1005202.
6	Essential role of microphthalmia transcription factor for DNA replication, mitosis and genomic stability in melanoma. Oncogene. 2011;30(20):2319-32.
7	Gene regulation and epigenetic remodeling in murine embryonic stem cells by c-Myc. PLoS One. 2009;4(11):e7839.
8	Identification of primary gene targets of TFAP2C in hormone responsive breast carcinoma cells. Genes Chromosomes Cancer. 2010;49(10):948-62.
9	Inhibition of p53 expression modifies the specificity of chromatin binding by the androgen receptor. Oncotarget. 2012;3(2):183-94.
10	Molecular interactions between HNF4a, FOXA2 and GABP identified at regulatory DNA elements through ChIP-sequencing. Nucleic Acids Res. 2009;37(22):7498-508.
11	Genomewide analyses define different modes of transcriptional regulation by peroxisome proliferator-activated receptor. PLoS One. 2011;6(1):e16344.
12	Characterization of genomic vitamin D receptor binding sites through chromatin looping and opening. PLoS One. 2014;9(4):e96184.
13	Vitamin D receptor ChIP-seq in primary CD4+ cells: relationship to serum 25-hydroxyvitamin D levels and autoimmune disease. BMC Med. 2013;11:163.
14	Discovering hematopoietic mechanisms through genome-wide analysis of GATA factor chromatin occupancy. Mol Cell. 2009;36(4):667-81.
15	Genome-wide analysis of simultaneous GATA1/2, RUNX1, FLI1, and SCL binding in megakaryocytes identifies hematopoietic regulators. Dev Cell. 2011;20(5):597-609.
16	The transcriptional regulator BCL6 participates in the secondary gene regulatory response to vitamin D. Biochim Biophys Acta. 2015;1849(3):300-8.
17	SALL4 is a key transcription regulator in normal human hematopoiesis. Transfusion. 2013;53(5):1037-49.
18	Species-specific mechanisms control the activity of the Pit1/PIT1 phosphate transporter gene promoter in mouse and human. Gene. 2001 Nov 14;279(1):49-62.
19	Genome-wide analysis of transcription factor E2F1 mutant proteins reveals that N- and C-terminal protein interaction domains do not participate in targeting E2F1 to the human genome. J Biol Chem. 2011;286(14):11985-96.
20	Genome-wide analyses reveal properties of redundant and specific promoter occupancy within the ETS gene family. Genes Dev. 2007;21(15):1882-94.
21	Genome-wide analysis of p63 binding sites identifies AP-2 factors as co-regulators of epidermal differentiation. Nucleic Acids Res. 2012;40(15):7190-206.
22	Genome-wide Runx2 occupancy in prostate cancer cells suggests a role in regulating secretion. Nucleic Acids Res. 2012;40(8):3538-47.
23	Chromatin and transcriptional signatures for Nodal signaling during endoderm formation in hESCs. Dev Biol. 2011;357(2):492-504.
24	Chromatin immunoprecipitation on microarray analysis of Smad2/3 binding sites reveals roles of ETS1 and TFAP2A in transforming growth factor beta signaling. Mol Cell Biol. 2009;29(1):172-86.
25	ChIP-seq defined genome-wide map of TGF/SMAD4 targets: implications with clinical outcome of ovarian cancer. PLoS One. 2011;6(7):e22606.

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