General Information of Drug Transporter (DT)
DT ID DTD0352 Transporter Info
Gene Name SLC3A2
Transporter Name Lymphocyte activation antigen 4F2
Gene ID
6520
UniProt ID
P08195

Transcriptional Regulation of This DT (TSR)

TF Superclass1: Basic domains

      Class1.1: Basic leucine zipper factors

Click to Show/Hide the Full List of 9 TF(s) Regulating This DT

        BACH2 

Click to Show/Hide to Show 1 Transcriptional Phenomena      

       Transcriptional Phenomenon1

Direct binding to SLC3A2 gene [1]

TF Protein Name

Transcription regulator protein BACH2 Transcription Factor Info

Tissue

Blood

Related DT Changes

Direct regulating

Experiment method

TF-transporter regulations were collected from ChIP-Seq datasets.

Detailed Description

Transcription regulator protein BACH2 (BACH2) can directly bind to the SLC3A2 gene, which in turn affects the expression or function of the drug transporter Lymphocyte activation antigen 4F2.

        CEBPA 

Click to Show/Hide to Show 1 Transcriptional Phenomena      

       Transcriptional Phenomenon1

Direct binding to SLC3A2 gene [2]

TF Protein Name

CCAAT/enhancer-binding protein alpha Transcription Factor Info

Tissue

Blood; Bone marrow; Liver

Related DT Changes

Direct regulating

Experiment method

TF-transporter regulations were collected from ChIP-Seq datasets.

Detailed Description

CCAAT/enhancer-binding protein alpha (CEBPA) can directly bind to the SLC3A2 gene, which in turn affects the expression or function of the drug transporter Lymphocyte activation antigen 4F2.

        CREB1 

Click to Show/Hide to Show 1 Transcriptional Phenomena      

       Transcriptional Phenomenon1

Direct binding to SLC3A2 gene [3]

TF Protein Name

Cyclic AMP-responsive element-binding protein 1 Transcription Factor Info

Tissue

Blood; Bone marrow; Liver

Related DT Changes

Direct regulating

Experiment method

TF-transporter regulations were collected from ChIP-Seq datasets.

Detailed Description

Cyclic AMP-responsive element-binding protein 1 (CREB1) can directly bind to the SLC3A2 gene, which in turn affects the expression or function of the drug transporter Lymphocyte activation antigen 4F2.

        FOSL1 

Click to Show/Hide to Show 1 Transcriptional Phenomena      

       Transcriptional Phenomenon1

Direct binding to SLC3A2 gene [2]

TF Protein Name

Fos-related antigen 1 Transcription Factor Info

Tissue

Bone marrow; Breast; Colon

Related DT Changes

Direct regulating

Experiment method

TF-transporter regulations were collected from ChIP-Seq datasets.

Detailed Description

Fos-related antigen 1 (FOSL1) can directly bind to the SLC3A2 gene, which in turn affects the expression or function of the drug transporter Lymphocyte activation antigen 4F2.

        FOSL2 

Click to Show/Hide to Show 1 Transcriptional Phenomena      

       Transcriptional Phenomenon1

Direct binding to SLC3A2 gene [4]

TF Protein Name

Fos-related antigen 2 Transcription Factor Info

Tissue

Brain; Breast; Liver; Lung

Related DT Changes

Direct regulating

Experiment method

TF-transporter regulations were collected from ChIP-Seq datasets.

Detailed Description

Fos-related antigen 2 (FOSL2) can directly bind to the SLC3A2 gene, which in turn affects the expression or function of the drug transporter Lymphocyte activation antigen 4F2.

        JUNB 

Click to Show/Hide to Show 1 Transcriptional Phenomena      

       Transcriptional Phenomenon1

Direct binding to SLC3A2 gene [3]

TF Protein Name

Transcription factor JunB Transcription Factor Info

Tissue

Aorta

Related DT Changes

Direct regulating

Experiment method

TF-transporter regulations were collected from ChIP-Seq datasets.

Detailed Description

Transcription factor JunB (JUNB) can directly bind to the SLC3A2 gene, which in turn affects the expression or function of the drug transporter Lymphocyte activation antigen 4F2.

        JUND 

Click to Show/Hide to Show 1 Transcriptional Phenomena      

       Transcriptional Phenomenon1

Direct binding to SLC3A2 gene [4]

TF Protein Name

Transcription factor JunD Transcription Factor Info

Tissue

Blood; Bone marrow; Brain; Breast; Cervix; Colon; Coronary artery; Embryo; Liver; Lung

Related DT Changes

Direct regulating

Experiment method

TF-transporter regulations were collected from ChIP-Seq datasets.

Detailed Description

Transcription factor JunD (JUND) can directly bind to the SLC3A2 gene, which in turn affects the expression or function of the drug transporter Lymphocyte activation antigen 4F2.

        MAFF 

Click to Show/Hide to Show 1 Transcriptional Phenomena      

       Transcriptional Phenomenon1

Direct binding to SLC3A2 gene [1]

TF Protein Name

Transcription factor MafF Transcription Factor Info

Tissue

Bone marrow; Liver

Related DT Changes

Direct regulating

Experiment method

TF-transporter regulations were collected from ChIP-Seq datasets.

Detailed Description

Transcription factor MafF (MAFF) can directly bind to the SLC3A2 gene, which in turn affects the expression or function of the drug transporter Lymphocyte activation antigen 4F2.

        MAFK 

Click to Show/Hide to Show 1 Transcriptional Phenomena      

       Transcriptional Phenomenon1

Direct binding to SLC3A2 gene [2]

TF Protein Name

Transcription factor MafK Transcription Factor Info

Tissue

Blood; Bone marrow; Cervix; Colon; Embryo; Liver; Lung

Related DT Changes

Direct regulating

Experiment method

TF-transporter regulations were collected from ChIP-Seq datasets.

Detailed Description

Transcription factor MafK (MAFK) can directly bind to the SLC3A2 gene, which in turn affects the expression or function of the drug transporter Lymphocyte activation antigen 4F2.

      Class1.2: Basic helix-loop-helix factors

Click to Show/Hide the Full List of 2 TF(s) Regulating This DT

        MITF 

Click to Show/Hide to Show 1 Transcriptional Phenomena      

       Transcriptional Phenomenon1

Activation of SLC3A2 gene in melanoma condition [5]

TF Protein Name

Microphthalmia-associated transcription factor Transcription Factor Info

Studied Phenotype

.

Related DT Changes

Up regulating

Detailed Description

Microphthalmia-associated transcription factor (MITF) has been reported to activate the transcription of SLC3A2 gene in melanoma condition, which leads to an increased expression of the drug transporter Lymphocyte activation antigen 4F2.

        TCF3 

Click to Show/Hide to Show 1 Transcriptional Phenomena      

       Transcriptional Phenomenon1

Direct binding to SLC3A2 gene [3]

TF Protein Name

Transcription factor E2-alpha Transcription Factor Info

Tissue

Blood

Related DT Changes

Direct regulating

Experiment method

TF-transporter regulations were collected from ChIP-Seq datasets.

Detailed Description

Transcription factor E2-alpha (TCF3) can directly bind to the SLC3A2 gene, which in turn affects the expression or function of the drug transporter Lymphocyte activation antigen 4F2.

      Class1.3: Basic helix-span-helix factors

Click to Show/Hide the Full List of 2 TF(s) Regulating This DT

        TFAP2A 

Click to Show/Hide to Show 2 Transcriptional Phenomena      

       Transcriptional Phenomenon1

Binding to SLC3A2 gene in MCF7 cells [6]

TF Protein Name

Transcription factor AP-2-alpha Transcription Factor Info

Related DT Changes

Direct regulating

Detailed Description

Transcription factor AP-2-alpha (TFAP2A) has been reported to bind to the transcription of SLC3A2 gene in MCF7 cells, which leads to an affected expression of the drug transporter Lymphocyte activation antigen 4F2.

       Transcriptional Phenomenon2

Direct binding to SLC3A2 gene [4]

TF Protein Name

Transcription factor AP-2-alpha Transcription Factor Info

Tissue

Cervix

Related DT Changes

Direct regulating

Experiment method

TF-transporter regulations were collected from ChIP-Seq datasets.

Detailed Description

Transcription factor AP-2-alpha (TFAP2A) can directly bind to the SLC3A2 gene, which in turn affects the expression or function of the drug transporter Lymphocyte activation antigen 4F2.

        TFAP2C 

Click to Show/Hide to Show 2 Transcriptional Phenomena      

       Transcriptional Phenomenon1

Activation of SLC3A2 gene in breast cancer condition [7]

TF Protein Name

Transcription factor AP-2 gamma Transcription Factor Info

Studied Phenotype

.

Related DT Changes

Up regulating

Detailed Description

Transcription factor AP-2 gamma (TFAP2C) has been reported to activate the transcription of SLC3A2 gene in breast cancer condition, which leads to an increased expression of the drug transporter Lymphocyte activation antigen 4F2.

       Transcriptional Phenomenon2

Direct binding to SLC3A2 gene [1]

TF Protein Name

Transcription factor AP-2 gamma Transcription Factor Info

Tissue

Breast; Cervix; Skin

Related DT Changes

Direct regulating

Experiment method

TF-transporter regulations were collected from ChIP-Seq datasets.

Detailed Description

Transcription factor AP-2 gamma (TFAP2C) can directly bind to the SLC3A2 gene, which in turn affects the expression or function of the drug transporter Lymphocyte activation antigen 4F2.

TF Superclass2: Zinc-coordinating DNA-binding domains

      Class2.1: Nuclear receptors with C4 zinc fingers

Click to Show/Hide the Full List of 6 TF(s) Regulating This DT

        ESR1 

Click to Show/Hide to Show 1 Transcriptional Phenomena      

       Transcriptional Phenomenon1

Direct binding to SLC3A2 gene [1]

TF Protein Name

Estrogen receptor Transcription Factor Info

Tissue

Breast

Related DT Changes

Direct regulating

Experiment method

TF-transporter regulations were collected from ChIP-Seq datasets.

Detailed Description

Estrogen receptor (ESR1) can directly bind to the SLC3A2 gene, which in turn affects the expression or function of the drug transporter Lymphocyte activation antigen 4F2.

        NR2F2 

Click to Show/Hide to Show 1 Transcriptional Phenomena      

       Transcriptional Phenomenon1

Direct binding to SLC3A2 gene [2]

TF Protein Name

COUP transcription factor 2 Transcription Factor Info

Tissue

Bone marrow; Breast

Related DT Changes

Direct regulating

Experiment method

TF-transporter regulations were collected from ChIP-Seq datasets.

Detailed Description

COUP transcription factor 2 (NR2F2) can directly bind to the SLC3A2 gene, which in turn affects the expression or function of the drug transporter Lymphocyte activation antigen 4F2.

        PGR 

Click to Show/Hide to Show 1 Transcriptional Phenomena      

       Transcriptional Phenomenon1

Direct binding to SLC3A2 gene [3]

TF Protein Name

Progesterone receptor Transcription Factor Info

Tissue

Breast

Related DT Changes

Direct regulating

Experiment method

TF-transporter regulations were collected from ChIP-Seq datasets.

Detailed Description

Progesterone receptor (PGR) can directly bind to the SLC3A2 gene, which in turn affects the expression or function of the drug transporter Lymphocyte activation antigen 4F2.

        PPARG 

Click to Show/Hide to Show 1 Transcriptional Phenomena      

       Transcriptional Phenomenon1

Direct binding to SLC3A2 gene [2]

TF Protein Name

Peroxisome proliferator-activated receptor gamma Transcription Factor Info

Tissue

Embryo

Related DT Changes

Direct regulating

Experiment method

TF-transporter regulations were collected from ChIP-Seq datasets.

Detailed Description

Peroxisome proliferator-activated receptor gamma (PPARG) can directly bind to the SLC3A2 gene, which in turn affects the expression or function of the drug transporter Lymphocyte activation antigen 4F2.

        RXRG 

Click to Show/Hide to Show 1 Transcriptional Phenomena      

       Transcriptional Phenomenon1

Direct binding to SLC3A2 gene [3]

TF Protein Name

Retinoic acid receptor RXR-gamma Transcription Factor Info

Tissue

Blood

Related DT Changes

Direct regulating

Experiment method

TF-transporter regulations were collected from ChIP-Seq datasets.

Detailed Description

Retinoic acid receptor RXR-gamma (RXRG) can directly bind to the SLC3A2 gene, which in turn affects the expression or function of the drug transporter Lymphocyte activation antigen 4F2.

        VDR 

Click to Show/Hide to Show 1 Transcriptional Phenomena      

       Transcriptional Phenomenon1

Binding to SLC3A2 gene in health condition [8]

TF Protein Name

Vitamin D3 receptor Transcription Factor Info

Studied Phenotype

.

Related DT Changes

Direct regulating

Detailed Description

Vitamin D3 receptor (VDR) has been reported to bind to the transcription of SLC3A2 gene in health condition, which leads to an affected expression of the drug transporter Lymphocyte activation antigen 4F2.

      Class2.2: Other C4 zinc finger-type factors

Click to Show/Hide the Full List of 2 TF(s) Regulating This DT

        GATA1 

Click to Show/Hide to Show 1 Transcriptional Phenomena      

       Transcriptional Phenomenon1

Direct binding to SLC3A2 gene [2]

TF Protein Name

Erythroid transcription factor Transcription Factor Info

Tissue

Blood; Bone marrow; Liver

Related DT Changes

Direct regulating

Experiment method

TF-transporter regulations were collected from ChIP-Seq datasets.

Detailed Description

Erythroid transcription factor (GATA1) can directly bind to the SLC3A2 gene, which in turn affects the expression or function of the drug transporter Lymphocyte activation antigen 4F2.

        GATA2 

Click to Show/Hide to Show 1 Transcriptional Phenomena      

       Transcriptional Phenomenon1

Activation of SLC3A2 gene in hematopoiesis condition [9]

TF Protein Name

Endothelial transcription factor GATA-2 Transcription Factor Info

Studied Phenotype

.

Related DT Changes

Up regulating

Detailed Description

Endothelial transcription factor GATA-2 (GATA2) has been reported to activate the transcription of SLC3A2 gene in hematopoiesis condition, which leads to an increased expression of the drug transporter Lymphocyte activation antigen 4F2.

      Class2.3: C2H2 zinc finger factors

Click to Show/Hide the Full List of 14 TF(s) Regulating This DT

        CTCF 

Click to Show/Hide to Show 1 Transcriptional Phenomena      

       Transcriptional Phenomenon1

Direct binding to SLC3A2 gene [4]

TF Protein Name

Transcriptional repressor CTCF Transcription Factor Info

Tissue

Brain

Related DT Changes

Direct regulating

Experiment method

TF-transporter regulations were collected from ChIP-Seq datasets.

Detailed Description

Transcriptional repressor CTCF (CTCF) can directly bind to the SLC3A2 gene, which in turn affects the expression or function of the drug transporter Lymphocyte activation antigen 4F2.

        CTCFL 

Click to Show/Hide to Show 1 Transcriptional Phenomena      

       Transcriptional Phenomenon1

Direct binding to SLC3A2 gene [2]

TF Protein Name

Transcriptional repressor CTCFL Transcription Factor Info

Tissue

Bone marrow

Related DT Changes

Direct regulating

Experiment method

TF-transporter regulations were collected from ChIP-Seq datasets.

Detailed Description

Transcriptional repressor CTCFL (CTCFL) can directly bind to the SLC3A2 gene, which in turn affects the expression or function of the drug transporter Lymphocyte activation antigen 4F2.

        EGR1 

Click to Show/Hide to Show 1 Transcriptional Phenomena      

       Transcriptional Phenomenon1

Binding to SLC3A2 gene in erythroleukemia condition [10]

TF Protein Name

Early growth response protein 1 Transcription Factor Info

Studied Phenotype

.

Related DT Changes

Direct regulating

Detailed Description

Early growth response protein 1 (EGR1) has been reported to bind to the transcription of SLC3A2 gene in erythroleukemia condition, which leads to an affected expression of the drug transporter Lymphocyte activation antigen 4F2.

        GLIS1 

Click to Show/Hide to Show 1 Transcriptional Phenomena      

       Transcriptional Phenomenon1

Direct binding to SLC3A2 gene [3]

TF Protein Name

Zinc finger protein GLIS1 Transcription Factor Info

Tissue

Blood; Colon

Related DT Changes

Direct regulating

Experiment method

TF-transporter regulations were collected from ChIP-Seq datasets.

Detailed Description

Zinc finger protein GLIS1 (GLIS1) can directly bind to the SLC3A2 gene, which in turn affects the expression or function of the drug transporter Lymphocyte activation antigen 4F2.

        KLF1 

Click to Show/Hide to Show 1 Transcriptional Phenomena      

       Transcriptional Phenomenon1

Direct binding to SLC3A2 gene [3]

TF Protein Name

Krueppel-like factor 1 Transcription Factor Info

Tissue

Blood

Related DT Changes

Direct regulating

Experiment method

TF-transporter regulations were collected from ChIP-Seq datasets.

Detailed Description

Krueppel-like factor 1 (KLF1) can directly bind to the SLC3A2 gene, which in turn affects the expression or function of the drug transporter Lymphocyte activation antigen 4F2.

        KLF4 

Click to Show/Hide to Show 1 Transcriptional Phenomena      

       Transcriptional Phenomenon1

Direct binding to SLC3A2 gene [4]

TF Protein Name

Krueppel-like factor 4 Transcription Factor Info

Tissue

Foreskin; Pancreatic ductal; Skin

Related DT Changes

Direct regulating

Experiment method

TF-transporter regulations were collected from ChIP-Seq datasets.

Detailed Description

Krueppel-like factor 4 (KLF4) can directly bind to the SLC3A2 gene, which in turn affects the expression or function of the drug transporter Lymphocyte activation antigen 4F2.

        KLF5 

Click to Show/Hide to Show 2 Transcriptional Phenomena      

       Transcriptional Phenomenon1

Activation of SLC3A2 gene in gastric cancer condition [11]

TF Protein Name

Krueppel-like factor 5 Transcription Factor Info

Studied Phenotype

.

Related DT Changes

Up regulating

Detailed Description

Krueppel-like factor 5 (KLF5) has been reported to activate the transcription of SLC3A2 gene in gastric cancer condition, which leads to an increased expression of the drug transporter Lymphocyte activation antigen 4F2.

       Transcriptional Phenomenon2

Direct binding to SLC3A2 gene [4]

TF Protein Name

Krueppel-like factor 5 Transcription Factor Info

Tissue

Colon; Pancreatic ductal; Stomach

Related DT Changes

Direct regulating

Experiment method

TF-transporter regulations were collected from ChIP-Seq datasets.

Detailed Description

Krueppel-like factor 5 (KLF5) can directly bind to the SLC3A2 gene, which in turn affects the expression or function of the drug transporter Lymphocyte activation antigen 4F2.

        KLF9 

Click to Show/Hide to Show 1 Transcriptional Phenomena      

       Transcriptional Phenomenon1

Direct binding to SLC3A2 gene [1]

TF Protein Name

Krueppel-like factor 9 Transcription Factor Info

Related DT Changes

Direct regulating

Experiment method

TF-transporter regulations were collected from ChIP-Seq datasets.

Detailed Description

Krueppel-like factor 9 (KLF9) can directly bind to the SLC3A2 gene, which in turn affects the expression or function of the drug transporter Lymphocyte activation antigen 4F2.

        MAZ 

Click to Show/Hide to Show 1 Transcriptional Phenomena      

       Transcriptional Phenomenon1

Direct binding to SLC3A2 gene [1]

TF Protein Name

Myc-associated zinc finger protein Transcription Factor Info

Tissue

Blood; Bone marrow; Cervix; Liver; Lung

Related DT Changes

Direct regulating

Experiment method

TF-transporter regulations were collected from ChIP-Seq datasets.

Detailed Description

Myc-associated zinc finger protein (MAZ) can directly bind to the SLC3A2 gene, which in turn affects the expression or function of the drug transporter Lymphocyte activation antigen 4F2.

        SP1 

Click to Show/Hide to Show 1 Transcriptional Phenomena      

       Transcriptional Phenomenon1

Activation of SLC3A2 gene in colitis condition [12]

TF Protein Name

Transcription factor Sp1 Transcription Factor Info

Studied Phenotype

Colitis [ICD11: 1A40]

Tissue

Colon

Related DT Changes

Up regulating

Experimental Material

C57BL/6 mice

Detailed Description

Transcription factor Sp1 (SP1) has been reported to activate the transcription of SLC3A2 gene in colitis condition, which leads to an increased expression of the drug transporter Lymphocyte activation antigen 4F2.

        SP4 

Click to Show/Hide to Show 1 Transcriptional Phenomena      

       Transcriptional Phenomenon1

Direct binding to SLC3A2 gene [4]

TF Protein Name

Transcription factor Sp4 Transcription Factor Info

Tissue

Embryo

Related DT Changes

Direct regulating

Experiment method

TF-transporter regulations were collected from ChIP-Seq datasets.

Detailed Description

Transcription factor Sp4 (SP4) can directly bind to the SLC3A2 gene, which in turn affects the expression or function of the drug transporter Lymphocyte activation antigen 4F2.

        ZBTB7A 

Click to Show/Hide to Show 1 Transcriptional Phenomena      

       Transcriptional Phenomenon1

Direct binding to SLC3A2 gene [1]

TF Protein Name

Zinc finger and BTB domain-containing protein 7A Transcription Factor Info

Tissue

Bone marrow; Liver; Uterus

Related DT Changes

Direct regulating

Experiment method

TF-transporter regulations were collected from ChIP-Seq datasets.

Detailed Description

Zinc finger and BTB domain-containing protein 7A (ZBTB7A) can directly bind to the SLC3A2 gene, which in turn affects the expression or function of the drug transporter Lymphocyte activation antigen 4F2.

        ZNF263 

Click to Show/Hide to Show 2 Transcriptional Phenomena      

       Transcriptional Phenomenon1

Binding to SLC3A2 gene in K562 cells [13]

TF Protein Name

Zinc finger protein 263 Transcription Factor Info

Related DT Changes

Direct regulating

Detailed Description

Zinc finger protein 263 (ZNF263) has been reported to bind to the transcription of SLC3A2 gene in K562 cells, which leads to an affected expression of the drug transporter Lymphocyte activation antigen 4F2.

       Transcriptional Phenomenon2

Direct binding to SLC3A2 gene [4]

TF Protein Name

Zinc finger protein 263 Transcription Factor Info

Tissue

Bone marrow; Kidney

Related DT Changes

Direct regulating

Experiment method

TF-transporter regulations were collected from ChIP-Seq datasets.

Detailed Description

Zinc finger protein 263 (ZNF263) can directly bind to the SLC3A2 gene, which in turn affects the expression or function of the drug transporter Lymphocyte activation antigen 4F2.

        ZNF384 

Click to Show/Hide to Show 1 Transcriptional Phenomena      

       Transcriptional Phenomenon1

Direct binding to SLC3A2 gene [1]

TF Protein Name

Zinc finger protein 384 Transcription Factor Info

Tissue

Bone marrow

Related DT Changes

Direct regulating

Experiment method

TF-transporter regulations were collected from ChIP-Seq datasets.

Detailed Description

Zinc finger protein 384 (ZNF384) can directly bind to the SLC3A2 gene, which in turn affects the expression or function of the drug transporter Lymphocyte activation antigen 4F2.

TF Superclass3: Helix-turn-helix domains

      Class3.1: Homeo domain factors

Click to Show/Hide the Full List of 3 TF(s) Regulating This DT

        CUX1 

Click to Show/Hide to Show 1 Transcriptional Phenomena      

       Transcriptional Phenomenon1

Activation of SLC3A2 gene in multiple human cancer types condition [14]

TF Protein Name

Homeobox protein cut-like 1 Transcription Factor Info

Studied Phenotype

.

Related DT Changes

Up regulating

Detailed Description

Homeobox protein cut-like 1 (CUX1) has been reported to activate the transcription of SLC3A2 gene in multiple human cancer types condition, which leads to an increased expression of the drug transporter Lymphocyte activation antigen 4F2.

        POU2F2 

Click to Show/Hide to Show 1 Transcriptional Phenomena      

       Transcriptional Phenomenon1

Direct binding to SLC3A2 gene [2]

TF Protein Name

POU domain, class 2, transcription factor 2 Transcription Factor Info

Tissue

Blood

Related DT Changes

Direct regulating

Experiment method

TF-transporter regulations were collected from ChIP-Seq datasets.

Detailed Description

POU domain, class 2, transcription factor 2 (POU2F2) can directly bind to the SLC3A2 gene, which in turn affects the expression or function of the drug transporter Lymphocyte activation antigen 4F2.

        ZEB1 

Click to Show/Hide to Show 1 Transcriptional Phenomena      

       Transcriptional Phenomenon1

Repression of SLC3A2 gene in ovarian serous adenocarcinoma condition [15]

TF Protein Name

Zinc finger E-box-binding homeobox 1 Transcription Factor Info

Affected Drug/Substrate

Cisplatin

Studied Phenotype

Ovarian serous adenocarcinoma [2C73.02]

Tissue

Ovary

Related DT Changes

down regulating

Experimental Material

Human ovarian serous cystadenocarcinoma cells (SK-OV-3)

Detailed Description

Zinc finger E-box-binding homeobox 1 (ZEB1), influenced by the exogenous cisplatin, has been reported to repress the transcription of SLC3A2 gene in ovarian serous adenocarcinoma condition , which leads to a decreased expression of the drug transporter Lymphocyte activation antigen 4F2.

      Class3.3: Fork head / winged helix factors

Click to Show/Hide the Full List of 5 TF(s) Regulating This DT

        E2F1 

Click to Show/Hide to Show 3 Transcriptional Phenomena      

       Transcriptional Phenomenon1

Binding to SLC3A2 gene in MCF7 cells [6]

TF Protein Name

Transcription factor E2F1 Transcription Factor Info

Related DT Changes

Direct regulating

Detailed Description

Transcription factor E2F1 (E2F1) has been reported to bind to the transcription of SLC3A2 gene in MCF7 cells, which leads to an affected expression of the drug transporter Lymphocyte activation antigen 4F2.

       Transcriptional Phenomenon2

Binding to SLC3A2 gene in health condition [16]

TF Protein Name

Transcription factor E2F1 Transcription Factor Info

Studied Phenotype

.

Related DT Changes

Direct regulating

Detailed Description

Transcription factor E2F1 (E2F1) has been reported to bind to the transcription of SLC3A2 gene in health condition, which leads to an affected expression of the drug transporter Lymphocyte activation antigen 4F2.

       Transcriptional Phenomenon3

Direct binding to SLC3A2 gene [1]

TF Protein Name

Transcription factor E2F1 Transcription Factor Info

Tissue

Mesenchymal

Related DT Changes

Direct regulating

Experiment method

TF-transporter regulations were collected from ChIP-Seq datasets.

Detailed Description

Transcription factor E2F1 (E2F1) can directly bind to the SLC3A2 gene, which in turn affects the expression or function of the drug transporter Lymphocyte activation antigen 4F2.

        E2F4 

Click to Show/Hide to Show 2 Transcriptional Phenomena      

       Transcriptional Phenomenon1

Binding to SLC3A2 gene in health condition [17]

TF Protein Name

Transcription factor E2F4 Transcription Factor Info

Studied Phenotype

.

Related DT Changes

Direct regulating

Detailed Description

Transcription factor E2F4 (E2F4) has been reported to bind to the transcription of SLC3A2 gene in health condition, which leads to an affected expression of the drug transporter Lymphocyte activation antigen 4F2.

       Transcriptional Phenomenon2

Binding to SLC3A2 gene in health condition [18]

TF Protein Name

Transcription factor E2F4 Transcription Factor Info

Studied Phenotype

.

Related DT Changes

Direct regulating

Detailed Description

Transcription factor E2F4 (E2F4) has been reported to bind to the transcription of SLC3A2 gene in health condition, which leads to an affected expression of the drug transporter Lymphocyte activation antigen 4F2.

        E2F6 

Click to Show/Hide to Show 1 Transcriptional Phenomena      

       Transcriptional Phenomenon1

Direct binding to SLC3A2 gene [2]

TF Protein Name

Transcription factor E2F6 Transcription Factor Info

Tissue

Bone marrow; Lung

Related DT Changes

Direct regulating

Experiment method

TF-transporter regulations were collected from ChIP-Seq datasets.

Detailed Description

Transcription factor E2F6 (E2F6) can directly bind to the SLC3A2 gene, which in turn affects the expression or function of the drug transporter Lymphocyte activation antigen 4F2.

        FOXA1 

Click to Show/Hide to Show 1 Transcriptional Phenomena      

       Transcriptional Phenomenon1

Direct binding to SLC3A2 gene [1]

TF Protein Name

Hepatocyte nuclear factor 3-alpha Transcription Factor Info

Tissue

Breast; Liver; Lung; Prostate

Related DT Changes

Direct regulating

Experiment method

TF-transporter regulations were collected from ChIP-Seq datasets.

Detailed Description

Hepatocyte nuclear factor 3-alpha (FOXA1) can directly bind to the SLC3A2 gene, which in turn affects the expression or function of the drug transporter Lymphocyte activation antigen 4F2.

        FOXA2 

Click to Show/Hide to Show 2 Transcriptional Phenomena      

       Transcriptional Phenomenon1

Binding to SLC3A2 gene in health condition [19]

TF Protein Name

Hepatocyte nuclear factor 3-beta Transcription Factor Info

Studied Phenotype

.

Related DT Changes

Direct regulating

Detailed Description

Hepatocyte nuclear factor 3-beta (FOXA2) has been reported to bind to the transcription of SLC3A2 gene in health condition, which leads to an affected expression of the drug transporter Lymphocyte activation antigen 4F2.

       Transcriptional Phenomenon2

Direct binding to SLC3A2 gene [2]

TF Protein Name

Hepatocyte nuclear factor 3-beta Transcription Factor Info

Tissue

Colon

Related DT Changes

Direct regulating

Experiment method

TF-transporter regulations were collected from ChIP-Seq datasets.

Detailed Description

Hepatocyte nuclear factor 3-beta (FOXA2) can directly bind to the SLC3A2 gene, which in turn affects the expression or function of the drug transporter Lymphocyte activation antigen 4F2.

      Class3.5: Tryptophan cluster factors

Click to Show/Hide the Full List of 7 TF(s) Regulating This DT

        ELF1 

Click to Show/Hide to Show 1 Transcriptional Phenomena      

       Transcriptional Phenomenon1

Direct binding to SLC3A2 gene [1]

TF Protein Name

ETS-related transcription factor Elf-1 Transcription Factor Info

Tissue

Blood; Bone marrow; Breast; Liver; Lung; Mesenchymal

Related DT Changes

Direct regulating

Experiment method

TF-transporter regulations were collected from ChIP-Seq datasets.

Detailed Description

ETS-related transcription factor Elf-1 (ELF1) can directly bind to the SLC3A2 gene, which in turn affects the expression or function of the drug transporter Lymphocyte activation antigen 4F2.

        ERG 

Click to Show/Hide to Show 1 Transcriptional Phenomena      

       Transcriptional Phenomenon1

Direct binding to SLC3A2 gene [3]

TF Protein Name

Transcriptional regulator ERG Transcription Factor Info

Tissue

Aorta

Related DT Changes

Direct regulating

Experiment method

TF-transporter regulations were collected from ChIP-Seq datasets.

Detailed Description

Transcriptional regulator ERG (ERG) can directly bind to the SLC3A2 gene, which in turn affects the expression or function of the drug transporter Lymphocyte activation antigen 4F2.

        ETS1 

Click to Show/Hide to Show 1 Transcriptional Phenomena      

       Transcriptional Phenomenon1

Direct binding to SLC3A2 gene [4]

TF Protein Name

Protein C-ets-1 Transcription Factor Info

Tissue

Blood; Bone; Bone marrow; Kidney; Lung; Pancreas; Prostate

Related DT Changes

Direct regulating

Experiment method

TF-transporter regulations were collected from ChIP-Seq datasets.

Detailed Description

Protein C-ets-1 (ETS1) can directly bind to the SLC3A2 gene, which in turn affects the expression or function of the drug transporter Lymphocyte activation antigen 4F2.

        ETV1 

Click to Show/Hide to Show 1 Transcriptional Phenomena      

       Transcriptional Phenomenon1

Direct binding to SLC3A2 gene [2]

TF Protein Name

ETS translocation variant 1 Transcription Factor Info

Tissue

Prostate

Related DT Changes

Direct regulating

Experiment method

TF-transporter regulations were collected from ChIP-Seq datasets.

Detailed Description

ETS translocation variant 1 (ETV1) can directly bind to the SLC3A2 gene, which in turn affects the expression or function of the drug transporter Lymphocyte activation antigen 4F2.

        FLI1 

Click to Show/Hide to Show 1 Transcriptional Phenomena      

       Transcriptional Phenomenon1

Direct binding to SLC3A2 gene [3]

TF Protein Name

Friend leukemia integration 1 transcription factor Transcription Factor Info

Tissue

Blood; Mesenchymal; Vein

Related DT Changes

Direct regulating

Experiment method

TF-transporter regulations were collected from ChIP-Seq datasets.

Detailed Description

Friend leukemia integration 1 transcription factor (FLI1) can directly bind to the SLC3A2 gene, which in turn affects the expression or function of the drug transporter Lymphocyte activation antigen 4F2.

        GABPA 

Click to Show/Hide to Show 1 Transcriptional Phenomena      

       Transcriptional Phenomenon1

Direct binding to SLC3A2 gene [4]

TF Protein Name

GA-binding protein alpha chain Transcription Factor Info

Tissue

Bone marrow; Liver; Prostate

Related DT Changes

Direct regulating

Experiment method

TF-transporter regulations were collected from ChIP-Seq datasets.

Detailed Description

GA-binding protein alpha chain (GABPA) can directly bind to the SLC3A2 gene, which in turn affects the expression or function of the drug transporter Lymphocyte activation antigen 4F2.

        IRF1 

Click to Show/Hide to Show 1 Transcriptional Phenomena      

       Transcriptional Phenomenon1

Direct binding to SLC3A2 gene [3]

TF Protein Name

Interferon regulatory factor 1 Transcription Factor Info

Tissue

Aorta

Related DT Changes

Direct regulating

Experiment method

TF-transporter regulations were collected from ChIP-Seq datasets.

Detailed Description

Interferon regulatory factor 1 (IRF1) can directly bind to the SLC3A2 gene, which in turn affects the expression or function of the drug transporter Lymphocyte activation antigen 4F2.

      Class3.7: ARID domain factors

Click to Show/Hide the Full List of 2 TF(s) Regulating This DT

        ARID3A 

Click to Show/Hide to Show 1 Transcriptional Phenomena      

       Transcriptional Phenomenon1

Direct binding to SLC3A2 gene [4]

TF Protein Name

AT-rich interactive domain-containing protein 3A Transcription Factor Info

Tissue

Bone marrow; Liver

Related DT Changes

Direct regulating

Experiment method

TF-transporter regulations were collected from ChIP-Seq datasets.

Detailed Description

AT-rich interactive domain-containing protein 3A (ARID3A) can directly bind to the SLC3A2 gene, which in turn affects the expression or function of the drug transporter Lymphocyte activation antigen 4F2.

        KDM5B 

Click to Show/Hide to Show 1 Transcriptional Phenomena      

       Transcriptional Phenomenon1

Direct binding to SLC3A2 gene [1]

TF Protein Name

Lysine-specific demethylase 5B Transcription Factor Info

Tissue

Bone marrow; Breast

Related DT Changes

Direct regulating

Experiment method

TF-transporter regulations were collected from ChIP-Seq datasets.

Detailed Description

Lysine-specific demethylase 5B (KDM5B) can directly bind to the SLC3A2 gene, which in turn affects the expression or function of the drug transporter Lymphocyte activation antigen 4F2.

TF Superclass4: Other all-alpha-helical DNA-binding domains

      Class4.1: High-mobility group domain factors

Click to Show/Hide the Full List of 1 TF(s) Regulating This DT

        SOX2 

Click to Show/Hide to Show 1 Transcriptional Phenomena      

       Transcriptional Phenomenon1

Binding to SLC3A2 gene in HESC condition [20]

TF Protein Name

Transcription factor SOX-2 Transcription Factor Info

Studied Phenotype

.

Related DT Changes

Direct regulating

Detailed Description

Transcription factor SOX-2 (SOX2) has been reported to bind to the transcription of SLC3A2 gene in HESC condition, which leads to an affected expression of the drug transporter Lymphocyte activation antigen 4F2.

TF Superclass5: alpha-Helices exposed by beta-structures

      Class5.1: MADS box factors

Click to Show/Hide the Full List of 2 TF(s) Regulating This DT

        MEF2A 

Click to Show/Hide to Show 1 Transcriptional Phenomena      

       Transcriptional Phenomenon1

Direct binding to SLC3A2 gene [2]

TF Protein Name

Myocyte-specific enhancer factor 2A Transcription Factor Info

Tissue

Blood

Related DT Changes

Direct regulating

Experiment method

TF-transporter regulations were collected from ChIP-Seq datasets.

Detailed Description

Myocyte-specific enhancer factor 2A (MEF2A) can directly bind to the SLC3A2 gene, which in turn affects the expression or function of the drug transporter Lymphocyte activation antigen 4F2.

        SRF 

Click to Show/Hide to Show 1 Transcriptional Phenomena      

       Transcriptional Phenomenon1

Direct binding to SLC3A2 gene [3]

TF Protein Name

Serum response factor Transcription Factor Info

Tissue

Embryo; Uterus

Related DT Changes

Direct regulating

Experiment method

TF-transporter regulations were collected from ChIP-Seq datasets.

Detailed Description

Serum response factor (SRF) can directly bind to the SLC3A2 gene, which in turn affects the expression or function of the drug transporter Lymphocyte activation antigen 4F2.

TF Superclass6: Immunoglobulin fold

      Class6.1: Rel homology region factors

Click to Show/Hide the Full List of 3 TF(s) Regulating This DT

        EBF1 

Click to Show/Hide to Show 1 Transcriptional Phenomena      

       Transcriptional Phenomenon1

Direct binding to SLC3A2 gene [3]

TF Protein Name

Transcription factor COE1 Transcription Factor Info

Tissue

Blood

Related DT Changes

Direct regulating

Experiment method

TF-transporter regulations were collected from ChIP-Seq datasets.

Detailed Description

Transcription factor COE1 (EBF1) can directly bind to the SLC3A2 gene, which in turn affects the expression or function of the drug transporter Lymphocyte activation antigen 4F2.

        NFKB1 

Click to Show/Hide to Show 1 Transcriptional Phenomena      

       Transcriptional Phenomenon1

Activation of SLC3A2 gene in colitis condition [12]

TF Protein Name

Nuclear factor NF-kappa-B p105 subunit Transcription Factor Info

Studied Phenotype

Colitis [ICD11: 1A40]

Tissue

Colon

Related DT Changes

Up regulating

Experimental Material

C57BL/6 mice

Detailed Description

Nuclear factor NF-kappa-B p105 subunit (NFKB1) has been reported to activate the transcription of SLC3A2 gene in colitis condition, which leads to an increased expression of the drug transporter Lymphocyte activation antigen 4F2.

        RELA 

Click to Show/Hide to Show 1 Transcriptional Phenomena      

       Transcriptional Phenomenon1

Activation of SLC3A2 gene in fibrosarcoma condition [21]

TF Protein Name

Transcription factor p65 Transcription Factor Info

Studied Phenotype

.

Related DT Changes

Up regulating

Detailed Description

Transcription factor p65 (RELA) has been reported to activate the transcription of SLC3A2 gene in fibrosarcoma condition, which leads to an increased expression of the drug transporter Lymphocyte activation antigen 4F2.

      Class6.2: STAT domain factors

Click to Show/Hide the Full List of 1 TF(s) Regulating This DT

        STAT6 

Click to Show/Hide to Show 1 Transcriptional Phenomena      

       Transcriptional Phenomenon1

Activation of SLC3A2 gene in immune-mediated diseases condition [22]

TF Protein Name

Signal transducer and activator of transcription 6 Transcription Factor Info

Studied Phenotype

.

Related DT Changes

Up regulating

Detailed Description

Signal transducer and activator of transcription 6 (STAT6) has been reported to activate the transcription of SLC3A2 gene in immune-mediated diseases condition, which leads to an increased expression of the drug transporter Lymphocyte activation antigen 4F2.

      Class6.3: p53 domain factors

Click to Show/Hide the Full List of 1 TF(s) Regulating This DT

        TP53 

Click to Show/Hide to Show 1 Transcriptional Phenomena      

       Transcriptional Phenomenon1

Binding to SLC3A2 gene in HFKS condition [23]

TF Protein Name

Cellular tumor antigen p53 Transcription Factor Info

Related DT Changes

Direct regulating

Detailed Description

Cellular tumor antigen p53 (TP53) has been reported to bind to the transcription of SLC3A2 gene in HFKS condition, which leads to an affected expression of the drug transporter Lymphocyte activation antigen 4F2.

      Class6.4: Runt domain factors

Click to Show/Hide the Full List of 2 TF(s) Regulating This DT

        RUNX1 

Click to Show/Hide to Show 2 Transcriptional Phenomena      

       Transcriptional Phenomenon1

Binding to SLC3A2 gene in health condition [17]

TF Protein Name

Runt-related transcription factor 1 Transcription Factor Info

Studied Phenotype

.

Related DT Changes

Direct regulating

Detailed Description

Runt-related transcription factor 1 (RUNX1) has been reported to bind to the transcription of SLC3A2 gene in health condition, which leads to an affected expression of the drug transporter Lymphocyte activation antigen 4F2.

       Transcriptional Phenomenon2

Binding to SLC3A2 gene in megakaryocytes condition [24]

TF Protein Name

Runt-related transcription factor 1 Transcription Factor Info

Related DT Changes

Direct regulating

Detailed Description

Runt-related transcription factor 1 (RUNX1) has been reported to bind to the transcription of SLC3A2 gene in megakaryocytes condition, which leads to an affected expression of the drug transporter Lymphocyte activation antigen 4F2.

        RUNX3 

Click to Show/Hide to Show 1 Transcriptional Phenomena      

       Transcriptional Phenomenon1

Direct binding to SLC3A2 gene [1]

TF Protein Name

Runt-related transcription factor 3 Transcription Factor Info

Tissue

Blood

Related DT Changes

Direct regulating

Experiment method

TF-transporter regulations were collected from ChIP-Seq datasets.

Detailed Description

Runt-related transcription factor 3 (RUNX3) can directly bind to the SLC3A2 gene, which in turn affects the expression or function of the drug transporter Lymphocyte activation antigen 4F2.

      Class6.7: Grainyhead domain factors

Click to Show/Hide the Full List of 1 TF(s) Regulating This DT

        GRHL2 

Click to Show/Hide to Show 1 Transcriptional Phenomena      

       Transcriptional Phenomenon1

Direct binding to SLC3A2 gene [4]

TF Protein Name

Grainyhead-like protein 2 homolog Transcription Factor Info

Tissue

Breast; Bronchus; Ovary; Prostate

Related DT Changes

Direct regulating

Experiment method

TF-transporter regulations were collected from ChIP-Seq datasets.

Detailed Description

Grainyhead-like protein 2 homolog (GRHL2) can directly bind to the SLC3A2 gene, which in turn affects the expression or function of the drug transporter Lymphocyte activation antigen 4F2.

TF Superclass7: beta-Hairpin exposed by an alpha/beta-scaffold

      Class7.1: SMAD/NF-1 DNA-binding domain factors

Click to Show/Hide the Full List of 3 TF(s) Regulating This DT

        NFIC 

Click to Show/Hide to Show 1 Transcriptional Phenomena      

       Transcriptional Phenomenon1

Direct binding to SLC3A2 gene [4]

TF Protein Name

Nuclear factor 1 C-type Transcription Factor Info

Tissue

Blood

Related DT Changes

Direct regulating

Experiment method

TF-transporter regulations were collected from ChIP-Seq datasets.

Detailed Description

Nuclear factor 1 C-type (NFIC) can directly bind to the SLC3A2 gene, which in turn affects the expression or function of the drug transporter Lymphocyte activation antigen 4F2.

        SMAD3 

Click to Show/Hide to Show 1 Transcriptional Phenomena      

       Transcriptional Phenomenon1

Binding to SLC3A2 gene in HaCaT keratinocytes condition [25]

TF Protein Name

Mothers against decapentaplegic homolog 3 Transcription Factor Info

Related DT Changes

Direct regulating

Detailed Description

Mothers against decapentaplegic homolog 3 (SMAD3) has been reported to bind to the transcription of SLC3A2 gene in HaCaT keratinocytes condition, which leads to an affected expression of the drug transporter Lymphocyte activation antigen 4F2.

        SMAD4 

Click to Show/Hide to Show 1 Transcriptional Phenomena      

       Transcriptional Phenomenon1

Activation of SLC3A2 gene in health condition [26]

TF Protein Name

Mothers against decapentaplegic homolog 4 Transcription Factor Info

Studied Phenotype

.

Related DT Changes

Up regulating

Detailed Description

Mothers against decapentaplegic homolog 4 (SMAD4) has been reported to activate the transcription of SLC3A2 gene in health condition, which leads to an increased expression of the drug transporter Lymphocyte activation antigen 4F2.

TF Superclass8: beta-Sheet binding to DNA

      Class8.1: TATA-binding proteins

Click to Show/Hide the Full List of 1 TF(s) Regulating This DT

        TBP 

Click to Show/Hide to Show 1 Transcriptional Phenomena      

       Transcriptional Phenomenon1

Direct binding to SLC3A2 gene [2]

TF Protein Name

TATA-box-binding protein Transcription Factor Info

Tissue

Blood; Bone marrow; Cervix; Embryo; Liver

Related DT Changes

Direct regulating

Experiment method

TF-transporter regulations were collected from ChIP-Seq datasets.

Detailed Description

TATA-box-binding protein (TBP) can directly bind to the SLC3A2 gene, which in turn affects the expression or function of the drug transporter Lymphocyte activation antigen 4F2.

TF Superclass9: beta-Barrel DNA-binding domains

      Class9.1: Cold-shock domain factors

Click to Show/Hide the Full List of 1 TF(s) Regulating This DT

        YBX3 

Click to Show/Hide to Show 1 Transcriptional Phenomena      

       Transcriptional Phenomenon1

Activation of SLC3A2 gene in cervical cancer condition [27]

TF Protein Name

Y-box-binding protein 3 Transcription Factor Info

Studied Phenotype

Cervical cancer [ICD11: 2C77]

Tissue

Cervix

Related DT Changes

Up regulating

Experimental Material

Human human papillomavirus-related endocervical adenocarcinoma cells (HeLa)

Detailed Description

Y-box-binding protein 3 (YBX3) has been reported to activate the transcription of SLC3A2 gene in cervical cancer condition, which leads to an increased expression of the drug transporter Lymphocyte activation antigen 4F2.

TF Superclass10: Yet undefined DNA-binding domains

      Class10.1: Other factors

Click to Show/Hide the Full List of 1 TF(s) Regulating This DT

        GTF2B 

Click to Show/Hide to Show 1 Transcriptional Phenomena      

       Transcriptional Phenomenon1

Direct binding to SLC3A2 gene [2]

TF Protein Name

Transcription initiation factor IIB Transcription Factor Info

Tissue

Cervix; Lung

Related DT Changes

Direct regulating

Experiment method

TF-transporter regulations were collected from ChIP-Seq datasets.

Detailed Description

Transcription initiation factor IIB (GTF2B) can directly bind to the SLC3A2 gene, which in turn affects the expression or function of the drug transporter Lymphocyte activation antigen 4F2.

      Class10.5: GTF2I domain factors

Click to Show/Hide the Full List of 1 TF(s) Regulating This DT

        GTF2I 

Click to Show/Hide to Show 1 Transcriptional Phenomena      

       Transcriptional Phenomenon1

Direct binding to SLC3A2 gene [3]

TF Protein Name

General transcription factor II-I Transcription Factor Info

Tissue

Foreskin

Related DT Changes

Direct regulating

Experiment method

TF-transporter regulations were collected from ChIP-Seq datasets.

Detailed Description

General transcription factor II-I (GTF2I) can directly bind to the SLC3A2 gene, which in turn affects the expression or function of the drug transporter Lymphocyte activation antigen 4F2.
References
1 The Encyclopedia of DNA elements (ENCODE): data portal update. Nucleic Acids Res. 2018 Jan 4;46(D1):D794-D801
2 hTFtarget: A Comprehensive Database for Regulations of Human Transcription Factors and Their Targets. Genomics Proteomics Bioinformatics. 2020 Apr;18(2):120-383. (ID:ENSG00000168003)
3 NCBI GEO: archive for functional genomics data sets--update. Nucleic Acids Res. 2013 Jan;41(D1):D991-5.
4 Closure of the NCBI SRA and implications for the long-term future of genomics data storage. Genome Biol. 2011;12(3):402.
5 Essential role of microphthalmia transcription factor for DNA replication, mitosis and genomic stability in melanoma. Oncogene. 2011;30(20):2319-32.
6 A computational genomics approach to identify cis-regulatory modules from chromatin immunoprecipitation microarray data--a case study using E2F1. Genome Res. 2006;16(12):1585-95.
7 Identification of primary gene targets of TFAP2C in hormone responsive breast carcinoma cells. Genes Chromosomes Cancer. 2010;49(10):948-62.
8 Vitamin D receptor ChIP-seq in primary CD4+ cells: relationship to serum 25-hydroxyvitamin D levels and autoimmune disease. BMC Med. 2013;11:163.
9 Discovering hematopoietic mechanisms through genome-wide analysis of GATA factor chromatin occupancy. Mol Cell. 2009;36(4):667-81.
10 Global analysis of in vivo EGR1-binding sites in erythroleukemia cell using chromatin immunoprecipitation and massively parallel sequencing. Electrophoresis. 2010;31(17):2936-43.
11 Regulatory crosstalk between lineage-survival oncogenes KLF5, GATA4 and GATA6 cooperatively promotes gastric cancer development. Gut. 2015;64(5):707-19.
12 Characterization of the human intestinal CD98 promoter and its regulation by interferon-gamma. Am J Physiol Gastrointest Liver Physiol. 2007 Feb;292(2):G535-45.
13 Genomic targets of the KRAB and SCAN domain-containing zinc finger protein 263. J Biol Chem. 2010;285(2):1393-403.
14 p110 CUX1 homeodomain protein stimulates cell migration and invasion in part through a regulatory cascade culminating in the repression of E-cadherin and occludin. J Biol Chem. 2009;284(40):27701-11.
15 ZEB1 Promotes Chemoresistance to Cisplatin in Ovarian Cancer Cells by Suppressing SLC3A2. Chemotherapy. 2018;63(5):262-271.
16 Genome-wide analysis of transcription factor E2F1 mutant proteins reveals that N- and C-terminal protein interaction domains do not participate in targeting E2F1 to the human genome. J Biol Chem. 2011;286(14):11985-96.
17 Genome-wide analyses reveal properties of redundant and specific promoter occupancy within the ETS gene family. Genes Dev. 2007;21(15):1882-94.
18 Wide-ranging functions of E2F4 in transcriptional activation and repression revealed by genome-wide analysis. Nucleic Acids Res. 2011;39(9):3558-73.
19 Molecular interactions between HNF4a, FOXA2 and GABP identified at regulatory DNA elements through ChIP-sequencing. Nucleic Acids Res. 2009;37(22):7498-508.
20 Core transcriptional regulatory circuitry in human embryonic stem cells. Cell. 2005;122(6):947-56.
21 Modulation of gene expression regulated by the transcription factor NF-B/RelA. J Biol Chem. 2014;289(17):11927-11944.
22 Genome-wide profiling of interleukin-4 and STAT6 transcription factor regulation of human Th2 cell programming. Immunity. 2010;32(6):852-62.
23 Genome-wide analysis of p63 binding sites identifies AP-2 factors as co-regulators of epidermal differentiation. Nucleic Acids Res. 2012;40(15):7190-206.
24 Genome-wide analysis of simultaneous GATA1/2, RUNX1, FLI1, and SCL binding in megakaryocytes identifies hematopoietic regulators. Dev Cell. 2011;20(5):597-609.
25 Chromatin immunoprecipitation on microarray analysis of Smad2/3 binding sites reveals roles of ETS1 and TFAP2A in transforming growth factor beta signaling. Mol Cell Biol. 2009;29(1):172-86.
26 Chromatin and transcriptional signatures for Nodal signaling during endoderm formation in hESCs. Dev Biol. 2011;357(2):492-504.
27 The RNA-Binding Protein YBX3 Controls Amino Acid Levels by Regulating SLC mRNA Abundance. Cell Rep. 2019 Jun 11;27(11):3097-3106.e5.

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