General Information of Drug Transporter (DT)
DT ID DTD0096 Transporter Info
Gene Name SLC14A1
Protein Name Urea transporter 1
Gene ID
6563
UniProt ID
Q13336
3D Structure

Modelled Stucture

Method:Homology modeling

Teplate PDB:6QD5_A

Identity:99.157%

Minimized Score:-1063.343

Detail: Structure Info

Inter-species Structural Differences (ISD)
Ovis aries (Sheep)
        Gene Name SLC14A1
        UniProt ID
C5MK33
        UniProt Entry
UT1_SHEEP
        3D Structure

Method:Homology modeling

Teplate PDB:4EZC_A

Sequence Length:384

Identity:97.135%

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        Performance Minimized Score -1039.987 kcal/mol
Ramachandra Favored

Medium

QMEANBrane Quality

High

        Ramachandran Plot

Ramz Z Score:-0.6 ±0.4

Residues in Favored Region:371

Ramachandran favored:97.12%

Number of Outliers:1

Ramachandran outliers:0.26%

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        Local Quality

QMEANBrane Score:0.83

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References
1 Structure and permeation mechanism of a mammalian urea transporter. Proc Natl Acad Sci U S A. 2012 Jul 10;109(28):11194-9.

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