| General Information of DT | |||||
|---|---|---|---|---|---|
| DT ID | DTD0514 | ||||
| Gene Name | ANXA11 | ||||
| Protein Name | Annexin A11 | ||||
| Gene ID | |||||
| UniProt ID | |||||
| TCDB ID | |||||
| 3D Structure |
Modelled DT Structure Method:homology modeling Template PDB:6TU2_A Identity:96.508% Minimized Score:-997.911 kcal/mol Detail: Structure Info |
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| Synonyms | 56 kDa autoantigen; ALS23; ANX11; ANXA11; Annexin XI; Annexin-11; CAP-50; CAP50; Calcyclin-associated annexin 50 | ||||
| DT Family | General Secretory Pathway (SEC) Family ; | ||||
| Function | This transporter binds specifically to calcyclin in a calcium-dependent manner. Required for midbody formation and completion of the terminal phase of cytokinesis. | ||||
| Endogenous Substrate(s) | Proteins | ||||
| Variability Data of This Drug Transporter (DT) | |||||
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Regulatory Variability Data of This DT (VARIDT 4.0) |
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(α) Tissue Distribution Level of Annexin A11 |
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(β) Cell Distribution Level of Annexin A11 |
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(γ) Organelle Distribution Level of Annexin A11 |
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Regulatory Variability Data of This DT |
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(β) Post-translational Modification of Annexin A11 |
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(γ) Transcriptional Regulation of Annexin A11 |
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(δ) Epigenetic Regulation of Annexin A11 |
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(ε) Exogenous Modulation of Annexin A11 |
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Structural Variability Data of This DT |
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(α) Mutation-induced Structural Variation |
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(β) Inter-species Structural Differences |
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General Variability Data of This DT |
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(α) Genetic Polymorphisms of Annexin A11 |
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(β) Disease-specific Protein Abundances of Annexin A11 |
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(γ) Species- and Tissue-specific DT Abundances |
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