Drug Transporter (DT) Information

General Information of DT
DT ID DTD0367
Gene Name SLC44A5
Protein Name Choline transporter-like protein 5
Gene ID
204962
UniProt ID
Q8NCS7
TCDB ID
2.A.92.1.5
3D Structure

Modelled DT Structure

Method: multi-sequence alignment based machine learning

Detail: Structure Info

Synonyms CTL5; SLC44A5; Solute carrier family 44 member 5
DT Family Choline Transporter-Like (CTl) Family ;
Function This transmembrane tranporter mediates the biosynthetic process of phosphatidylcholine.
Endogenous Substrate(s) Choline
Variability Data of This Drug Transporter (DT)

Regulatory Variability Data of This DT (VARIDT 4.0)

(α) Tissue Distribution Level of Choline transporter-like protein 5
Tissue Distribution Level (TD)

(β) Cell Distribution Level of Choline transporter-like protein 5
Cell Distribution Level (CD)

(γ) Organelle Distribution Level of Choline transporter-like protein 5
Organelle Distribution Level (Subc)

Regulatory Variability Data of This DT

(β) Post-translational Modification of Choline transporter-like protein 5
Post-translational Modification (PTM)

(γ) Transcriptional Regulation of Choline transporter-like protein 5
Transcriptional Regulation (TSR)

(δ) Epigenetic Regulation of Choline transporter-like protein 5
Epigenetic Regulation (EGR)

(ε) Exogenous Modulation of Choline transporter-like protein 5
Exogenous Modulation (EGM)

General Variability Data of This DT

(α) Genetic Polymorphisms of Choline transporter-like protein 5
Genetic Polymorphisms of This DT (GPD)

(β) Disease-specific Protein Abundances of Choline transporter-like protein 5
Disease-specific Protein Abundances of This DT (DPAD)

(γ) Species- and Tissue-specific DT Abundances
Species/Tissue-specific Protein Abundances of This DT (S/TPAD)
Molecular Transporting Profile of This DT

Full List of Drug(s) Transported by This DT

 Clinical Trial Drug

 Click to Show/Hide the Full List of Drug:           1 Drugs in Total
Drug Name Highest Status Detail Indication ICD 11 Ref
Choline
 Phase 3 Drug Info Elderly bronchial asthma CA23 [1]
References
1 The molecular effects of a polymorphism in the 5'UTR of solute carrier family 44, member 5 that is associated with birth weight in Holsteins. PLoS One. 2012;7(7):e41267.

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