| General Information of DT | |||||
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| DT ID | DTD0287 | ||||
| Gene Name | SLC35A1 | ||||
| Protein Name | CMP-sialic acid transporter | ||||
| Gene ID | |||||
| UniProt ID | |||||
| TCDB ID | |||||
| 3D Structure |
Modelled DT Structure Method:homology modeling Template PDB:6OH4_A Identity:91.395% Minimized Score:-940.824 kcal/mol Detail: Structure Info |
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| Synonyms | CDG2F; CMP-SA-Tr; CMP-Sia-Tr; CMPST; CST; SLC35A1; Solute carrier family 35 member A1; hCST | ||||
| DT Family | Drug/Metabolite Transporter (DMT) Superfamily | ||||
| CMP-Sialate:CMP Antiporter (CSA) Family | |||||
| Function | This transporter mediates the transport of CMP-sialic acid from the cytosol into golgi vesicles where glycosyltransferases function. | ||||
| Endogenous Substrate(s) | CMP | ||||
| Variability Data of This Drug Transporter (DT) | |||||
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Regulatory Variability Data of This DT (VARIDT 4.0) |
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(α) Tissue Distribution Level of CMP-sialic acid transporter |
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(β) Cell Distribution Level of CMP-sialic acid transporter |
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(γ) Organelle Distribution Level of CMP-sialic acid transporter |
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Regulatory Variability Data of This DT |
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(β) Post-translational Modification of CMP-sialic acid transporter |
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(γ) Transcriptional Regulation of CMP-sialic acid transporter |
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(δ) Epigenetic Regulation of CMP-sialic acid transporter |
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(ε) Exogenous Modulation of CMP-sialic acid transporter |
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Structural Variability Data of This DT |
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(β) Inter-species Structural Differences |
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General Variability Data of This DT |
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(α) Genetic Polymorphisms of CMP-sialic acid transporter |
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(β) Disease-specific Protein Abundances of CMP-sialic acid transporter |
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(γ) Species- and Tissue-specific DT Abundances |
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