Drug Transporter (DT) Information

General Information of DT
DT ID DTD0213
Gene Name SLC25A5
Protein Name Adenine nucleotide translocator 2
Gene ID
292
UniProt ID
P05141
TCDB ID
2.A.29.1.1
3D Structure

Modelled DT Structure

Method:homology modeling

Template PDB:1OKC_A

Identity:89.226%

Minimized Score:-800.643 kcal/mol

Detail: Structure Info

Synonyms 2F1; AAC2; ADP,ATP carrier protein 2; ADP,ATP carrier protein, fibroblast isoform; ANT 2; ANT2; ADP/ATP translocase 2, N-terminally processed; SLC25A5; Solute carrier family 25 member 5; T2; T3; ADP/ATP translocase 2; ADP/ATP translocase 2, N-terminally processed
DT Family Mitochondrial Carrier (MC) Family ;
Function This transporter catalyzes the exchange of cytoplasmic ADP with mitochondrial ATP across the mitochondrial inner membrane. It may play a role in chromosome segregation.
Endogenous Substrate(s) ATP; ADP
Variability Data of This Drug Transporter (DT)

Regulatory Variability Data of This DT (VARIDT 4.0)

(α) Tissue Distribution Level of Adenine nucleotide translocator 2
Tissue Distribution Level (TD)

(β) Cell Distribution Level of Adenine nucleotide translocator 2
Cell Distribution Level (CD)

(γ) Organelle Distribution Level of Adenine nucleotide translocator 2
Organelle Distribution Level (Subc)

Regulatory Variability Data of This DT

(β) Post-translational Modification of Adenine nucleotide translocator 2
Post-translational Modification (PTM)

(γ) Transcriptional Regulation of Adenine nucleotide translocator 2
Transcriptional Regulation (TSR)

(δ) Epigenetic Regulation of Adenine nucleotide translocator 2
Epigenetic Regulation (EGR)

(ε) Exogenous Modulation of Adenine nucleotide translocator 2
Exogenous Modulation (EGM)

Structural Variability Data of This DT

(β) Inter-species Structural Differences
Inter-species Structural Differences (ISD)

General Variability Data of This DT

(α) Genetic Polymorphisms of Adenine nucleotide translocator 2
Genetic Polymorphisms of This DT (GPD)

(β) Disease-specific Protein Abundances of Adenine nucleotide translocator 2
Disease-specific Protein Abundances of This DT (DPAD)

(γ) Species- and Tissue-specific DT Abundances
Species/Tissue-specific Protein Abundances of This DT (S/TPAD)

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