Detail Information of Post-Translational Modifications

General Information of Drug Transporter (DT)
DT ID	DTD0213 Transporter Info
Gene Name	SLC25A5
Transporter Name	Adenine nucleotide translocator 2
Gene ID	292
UniProt ID	P05141

Post-Translational Modification of This DT
Overview ofSLC25A5 Modification Sites with Functional and Structural Information
Sequence	M T D A A V S F A K D F L A G G V A A A I S K T A V A P I E R V K L L L Q V Q H A S K Q I T A D K Q Y K G I I D C V V R I P K E Q G V L S F W R G N L A N V I R Y F P T Q A L N F A F K D K Y K Q I F L G G V D K R T Q F W L Y F A G N L A S G G A A G A T S L C F V Y P L D F A R T R L A A D V G K A G A E R E F R G L G D C L V K I Y K S D G I K G L Y Q G F N V S V Q G I I I Y R A A Y F G I Y D T A K G M L P D P K N T H I V I S W M I A Q T V T A V A G L T S Y P F D T V R R R M M M Q S G R K G T D I M Y T G T L D C W R K I A R D E G G K A F F K G A W S N V L R G M G G A F V L V L Y D E I K K Y T
PTM type	X-Acetylation X-Glutathionylation X-Malonylation X-Methylation X-Oxidation X-Phosphorylation X-Phosphorylation X-S-glutathionylation X-S-nitrosylation X-S-palmitoylation X-S-sulfhydration X-Succinylation X-Sulfoxidation X-SUMOylation X-Ubiquitination X: Amino Acid

Acetylation
Lysine	17 PTM Phenomena Related to This Residue		Click to Show/Hide the Full List
PTM Phenomenon1	Have the potential to influence SLC25A5			[1], [2]
Role of PTM	Potential impacts
Modified Residue	Lysine	Modified Location	10
Experimental Method	Co-Immunoprecipitation
Detailed Description	Acetylation at SLC25A5 Lysine 10 has the potential to affect its expression or activity.
PTM Phenomenon2	Have the potential to influence SLC25A5			[1], [3]
Role of PTM	Potential impacts
Modified Residue	Lysine	Modified Location	23
Experimental Method	Co-Immunoprecipitation
Detailed Description	Acetylation at SLC25A5 Lysine 23 has the potential to affect its expression or activity.
PTM Phenomenon3	Have the potential to influence SLC25A5			[4], [5]
Role of PTM	Potential impacts
Modified Residue	Lysine	Modified Location	33
Experimental Method	Co-Immunoprecipitation
Detailed Description	Acetylation at SLC25A5 Lysine 33 has the potential to affect its expression or activity.
PTM Phenomenon4	Have the potential to influence SLC25A5			[1], [4]
Role of PTM	Potential impacts
Modified Residue	Lysine	Modified Location	43
Experimental Method	Co-Immunoprecipitation
Detailed Description	Acetylation at SLC25A5 Lysine 43 has the potential to affect its expression or activity.
PTM Phenomenon5	Have the potential to influence SLC25A5			[6]
Role of PTM	Potential impacts
Modified Residue	Lysine	Modified Location	52
Experimental Method	Co-Immunoprecipitation
Detailed Description	Acetylation at SLC25A5 Lysine 52 has the potential to affect its expression or activity.
PTM Phenomenon6	Have the potential to influence SLC25A5			[2], [4]
Role of PTM	Potential impacts
Modified Residue	Lysine	Modified Location	63
Experimental Method	Co-Immunoprecipitation
Detailed Description	Acetylation at SLC25A5 Lysine 63 has the potential to affect its expression or activity.
PTM Phenomenon7	Have the potential to influence SLC25A5			[1], [7]
Role of PTM	Potential impacts
Modified Residue	Lysine	Modified Location	92
Experimental Method	Co-Immunoprecipitation
Detailed Description	Acetylation at SLC25A5 Lysine 92 has the potential to affect its expression or activity.
PTM Phenomenon8	Have the potential to influence SLC25A5			[5]
Role of PTM	Potential impacts
Modified Residue	Lysine	Modified Location	94
Experimental Method	Co-Immunoprecipitation
Detailed Description	Acetylation at SLC25A5 Lysine 94 has the potential to affect its expression or activity.
PTM Phenomenon9	Have the potential to influence SLC25A5			[1], [4]
Role of PTM	Potential impacts
Modified Residue	Lysine	Modified Location	96
Experimental Method	Co-Immunoprecipitation
Detailed Description	Acetylation at SLC25A5 Lysine 96 has the potential to affect its expression or activity.
PTM Phenomenon10	Have the potential to influence SLC25A5			[8]
Role of PTM	Potential impacts
Modified Residue	Lysine	Modified Location	105
Experimental Method	Co-Immunoprecipitation
Detailed Description	Acetylation at SLC25A5 Lysine 105 has the potential to affect its expression or activity.
PTM Phenomenon11	Have the potential to influence SLC25A5			[1], [4]
Role of PTM	Potential impacts
Modified Residue	Lysine	Modified Location	147
Experimental Method	Co-Immunoprecipitation
Detailed Description	Acetylation at SLC25A5 Lysine 147 has the potential to affect its expression or activity.
PTM Phenomenon12	Have the potential to influence SLC25A5			[8]
Role of PTM	Potential impacts
Modified Residue	Lysine	Modified Location	163
Experimental Method	Co-Immunoprecipitation
Detailed Description	Acetylation at SLC25A5 Lysine 163 has the potential to affect its expression or activity.
PTM Phenomenon13	Have the potential to influence SLC25A5			[1], [3]
Role of PTM	Potential impacts
Modified Residue	Lysine	Modified Location	166
Experimental Method	Co-Immunoprecipitation
Detailed Description	Acetylation at SLC25A5 Lysine 166 has the potential to affect its expression or activity.
PTM Phenomenon14	Have the potential to influence SLC25A5			[1], [4]
Role of PTM	Potential impacts
Modified Residue	Lysine	Modified Location	199
Experimental Method	Co-Immunoprecipitation
Detailed Description	Acetylation at SLC25A5 Lysine 199 has the potential to affect its expression or activity.
PTM Phenomenon15	Have the potential to influence SLC25A5			[1], [7]
Role of PTM	Potential impacts
Modified Residue	Lysine	Modified Location	268
Experimental Method	Co-Immunoprecipitation
Detailed Description	Acetylation at SLC25A5 Lysine 268 has the potential to affect its expression or activity.
PTM Phenomenon16	Have the potential to influence SLC25A5			[1], [7]
Role of PTM	Potential impacts
Modified Residue	Lysine	Modified Location	272
Experimental Method	Co-Immunoprecipitation
Detailed Description	Acetylation at SLC25A5 Lysine 272 has the potential to affect its expression or activity.
PTM Phenomenon17	Have the potential to influence SLC25A5			[9]
Role of PTM	Potential impacts
Modified Residue	Lysine	Modified Location	295
Experimental Method	Co-Immunoprecipitation
Detailed Description	Acetylation at SLC25A5 Lysine 295 has the potential to affect its expression or activity.
Methionine	1 PTM Phenomena Related to This Residue		Click to Show/Hide the Full List
PTM Phenomenon1	Have the potential to influence SLC25A5			[10]
Role of PTM	Potential impacts
Modified Residue	Methionine	Modified Location	1
Experimental Method	Co-Immunoprecipitation
Detailed Description	Acetylation at SLC25A5 Methionine 1 has the potential to affect its expression or activity.
Threonine	1 PTM Phenomena Related to This Residue		Click to Show/Hide the Full List
PTM Phenomenon1	Have the potential to influence SLC25A5			[11], [12]
Role of PTM	Potential impacts
Modified Residue	Threonine	Modified Location	2
Experimental Method	Co-Immunoprecipitation
Detailed Description	Acetylation at SLC25A5 Threonine 2 has the potential to affect its expression or activity.
Glutathionylation
Cystine	1 PTM Phenomena Related to This Residue		Click to Show/Hide the Full List
PTM Phenomenon1	Have the potential to influence SLC25A5			[13]
Role of PTM	Potential impacts
Modified Residue	Cystine	Modified Location	257
Experimental Method	Co-Immunoprecipitation
Detailed Description	Glutathionylation at SLC25A5 Cystine 257 has the potential to affect its expression or activity.
Malonylation
Lysine	8 PTM Phenomena Related to This Residue		Click to Show/Hide the Full List
PTM Phenomenon1	Have the potential to influence SLC25A5			[14], [15]
Role of PTM	Potential impacts
Modified Residue	Lysine	Modified Location	23
Experimental Method	Co-Immunoprecipitation
Detailed Description	Malonylation at SLC25A5 Lysine 23 has the potential to affect its expression or activity.
PTM Phenomenon2	Have the potential to influence SLC25A5			[14]
Role of PTM	Potential impacts
Modified Residue	Lysine	Modified Location	33
Experimental Method	Co-Immunoprecipitation
Detailed Description	Malonylation at SLC25A5 Lysine 33 has the potential to affect its expression or activity.
PTM Phenomenon3	Have the potential to influence SLC25A5			[14], [15]
Role of PTM	Potential impacts
Modified Residue	Lysine	Modified Location	92
Experimental Method	Co-Immunoprecipitation
Detailed Description	Malonylation at SLC25A5 Lysine 92 has the potential to affect its expression or activity.
PTM Phenomenon4	Have the potential to influence SLC25A5			[14], [15]
Role of PTM	Potential impacts
Modified Residue	Lysine	Modified Location	96
Experimental Method	Co-Immunoprecipitation
Detailed Description	Malonylation at SLC25A5 Lysine 96 has the potential to affect its expression or activity.
PTM Phenomenon5	Have the potential to influence SLC25A5			[14]
Role of PTM	Potential impacts
Modified Residue	Lysine	Modified Location	105
Experimental Method	Co-Immunoprecipitation
Detailed Description	Malonylation at SLC25A5 Lysine 105 has the potential to affect its expression or activity.
PTM Phenomenon6	Have the potential to influence SLC25A5			[14], [15]
Role of PTM	Potential impacts
Modified Residue	Lysine	Modified Location	147
Experimental Method	Co-Immunoprecipitation
Detailed Description	Malonylation at SLC25A5 Lysine 147 has the potential to affect its expression or activity.
PTM Phenomenon7	Have the potential to influence SLC25A5			[14]
Role of PTM	Potential impacts
Modified Residue	Lysine	Modified Location	163
Experimental Method	Co-Immunoprecipitation
Detailed Description	Malonylation at SLC25A5 Lysine 163 has the potential to affect its expression or activity.
PTM Phenomenon8	Have the potential to influence SLC25A5			[14]
Role of PTM	Potential impacts
Modified Residue	Lysine	Modified Location	272
Experimental Method	Co-Immunoprecipitation
Detailed Description	Malonylation at SLC25A5 Lysine 272 has the potential to affect its expression or activity.
Methylation
Arginine	1 PTM Phenomena Related to This Residue		Click to Show/Hide the Full List
PTM Phenomenon1	Have the potential to influence SLC25A5			[16]
Role of PTM	Potential impacts
Modified Residue	Arginine	Modified Location	155
Experimental Method	Co-Immunoprecipitation
Detailed Description	Methylation at SLC25A5 Arginine 155 has the potential to affect its expression or activity.
Lysine	6 PTM Phenomena Related to This Residue		Click to Show/Hide the Full List
PTM Phenomenon1	Have the potential to influence SLC25A5			[17]
Role of PTM	Potential impacts
Modified Residue	Lysine	Modified Location	10
Experimental Method	Co-Immunoprecipitation
Detailed Description	Methylation at SLC25A5 Lysine 10 has the potential to affect its expression or activity.
PTM Phenomenon2	Have the potential to influence SLC25A5			[18]
Role of PTM	Potential impacts
Modified Residue	Lysine	Modified Location	43
Experimental Method	Co-Immunoprecipitation
Detailed Description	Methylation at SLC25A5 Lysine 43 has the potential to affect its expression or activity.
PTM Phenomenon3	Have the potential to influence SLC25A5			[19]
Role of PTM	Potential impacts
Modified Residue	Lysine	Modified Location	52
Related Enzyme	Adenine nucleotide translocase lysine N-methyltransferase (ANTKMT)
Experimental Method	Co-Immunoprecipitation
Detailed Description	Methylation at SLC25A5 Lysine 52 has the potential to affect its expression or activity.
PTM Phenomenon4	Have the potential to influence SLC25A5			[20]
Role of PTM	Potential impacts
Modified Residue	Lysine	Modified Location	147
Experimental Method	Co-Immunoprecipitation
Detailed Description	Methylation at SLC25A5 Lysine 147 has the potential to affect its expression or activity.
PTM Phenomenon5	Have the potential to influence SLC25A5			[21]
Role of PTM	Potential impacts
Modified Residue	Lysine	Modified Location	166
Experimental Method	Co-Immunoprecipitation
Detailed Description	Methylation at SLC25A5 Lysine 166 has the potential to affect its expression or activity.
PTM Phenomenon6	Have the potential to influence SLC25A5			[8], [22]
Role of PTM	Potential impacts
Modified Residue	Lysine	Modified Location	272
Experimental Method	Co-Immunoprecipitation
Detailed Description	Methylation at SLC25A5 Lysine 272 has the potential to affect its expression or activity.
Oxidation
Cystine	3 PTM Phenomena Related to This Residue		Click to Show/Hide the Full List
PTM Phenomenon1	Have the potential to influence SLC25A5			[23], [24]
Role of PTM	Potential impacts
Modified Residue	Cystine	Modified Location	57
Experimental Method	Co-Immunoprecipitation
Detailed Description	Oxidation at SLC25A5 Cystine 57 has the potential to affect its expression or activity.
PTM Phenomenon2	Have the potential to influence SLC25A5			[23], [24]
Role of PTM	Potential impacts
Modified Residue	Cystine	Modified Location	129
Experimental Method	Co-Immunoprecipitation
Detailed Description	Oxidation at SLC25A5 Cystine 129 has the potential to affect its expression or activity.
PTM Phenomenon3	Have the potential to influence SLC25A5			[23], [24]
Role of PTM	Potential impacts
Modified Residue	Cystine	Modified Location	257
Experimental Method	Co-Immunoprecipitation
Detailed Description	Oxidation at SLC25A5 Cystine 257 has the potential to affect its expression or activity.
Phosphorylation
Serine	9 PTM Phenomena Related to This Residue		Click to Show/Hide the Full List
PTM Phenomenon1	Have the potential to influence SLC25A5			[25], [26]
Role of PTM	Potential impacts
Modified Residue	Serine	Modified Location	7
Experimental Method	Co-Immunoprecipitation
Detailed Description	Phosphorylation at SLC25A5 Serine 7 has the potential to affect its expression or activity.
PTM Phenomenon2	Have the potential to influence SLC25A5			[27], [28]
Role of PTM	Potential impacts
Modified Residue	Serine	Modified Location	22
Experimental Method	Co-Immunoprecipitation
Detailed Description	Phosphorylation at SLC25A5 Serine 22 has the potential to affect its expression or activity.
PTM Phenomenon3	Have the potential to influence SLC25A5			[28], [29]
Role of PTM	Potential impacts
Modified Residue	Serine	Modified Location	42
Experimental Method	Co-Immunoprecipitation
Detailed Description	Phosphorylation at SLC25A5 Serine 42 has the potential to affect its expression or activity.
PTM Phenomenon4	Have the potential to influence SLC25A5			[27], [30]
Role of PTM	Potential impacts
Modified Residue	Serine	Modified Location	69
Experimental Method	Co-Immunoprecipitation
Detailed Description	Phosphorylation at SLC25A5 Serine 69 has the potential to affect its expression or activity.
PTM Phenomenon5	Have the potential to influence SLC25A5			[31], [32]
Role of PTM	Potential impacts
Modified Residue	Serine	Modified Location	119
Experimental Method	Co-Immunoprecipitation
Detailed Description	Phosphorylation at SLC25A5 Serine 119 has the potential to affect its expression or activity.
PTM Phenomenon6	Have the potential to influence SLC25A5			[27], [33]
Role of PTM	Potential impacts
Modified Residue	Serine	Modified Location	127
Experimental Method	Co-Immunoprecipitation
Detailed Description	Phosphorylation at SLC25A5 Serine 127 has the potential to affect its expression or activity.
PTM Phenomenon7	Have the potential to influence SLC25A5			[34]
Role of PTM	Potential impacts
Modified Residue	Serine	Modified Location	167
Experimental Method	Co-Immunoprecipitation
Detailed Description	Phosphorylation at SLC25A5 Serine 167 has the potential to affect its expression or activity.
PTM Phenomenon8	Have the potential to influence SLC25A5			[35]
Role of PTM	Potential impacts
Modified Residue	Serine	Modified Location	242
Experimental Method	Co-Immunoprecipitation
Detailed Description	Phosphorylation at SLC25A5 Serine 242 has the potential to affect its expression or activity.
PTM Phenomenon9	Have the potential to influence SLC25A5			[27], [36]
Role of PTM	Potential impacts
Modified Residue	Serine	Modified Location	276
Experimental Method	Co-Immunoprecipitation
Detailed Description	Phosphorylation at SLC25A5 Serine 276 has the potential to affect its expression or activity.
Threonine	9 PTM Phenomena Related to This Residue		Click to Show/Hide the Full List
PTM Phenomenon1	.			[37]
Role of PTM	Influencing the Disease Progression
Modified Residue	Threonine	Modified Location	107
Experimental Material(s)	prostate cancer tissue
Experimental Method	Co-Immunoprecipitation
Detailed Description	Phosphorylation at SLC25A5 Threonine 107 have been reported to inhibit the apoptosis of prostate cancer cells.
PTM Phenomenon2	Have the potential to influence SLC25A5			[38], [39]
Role of PTM	Potential impacts
Modified Residue	Threonine	Modified Location	2
Experimental Method	Co-Immunoprecipitation
Detailed Description	Phosphorylation at SLC25A5 Threonine 2 has the potential to affect its expression or activity.
PTM Phenomenon3	Have the potential to influence SLC25A5			[40], [41]
Role of PTM	Potential impacts
Modified Residue	Threonine	Modified Location	24
Experimental Method	Co-Immunoprecipitation
Detailed Description	Phosphorylation at SLC25A5 Threonine 24 has the potential to affect its expression or activity.
PTM Phenomenon4	Have the potential to influence SLC25A5			[27], [30]
Role of PTM	Potential impacts
Modified Residue	Threonine	Modified Location	84
Experimental Method	Co-Immunoprecipitation
Detailed Description	Phosphorylation at SLC25A5 Threonine 84 has the potential to affect its expression or activity.
PTM Phenomenon5	Have the potential to influence SLC25A5			[27], [33]
Role of PTM	Potential impacts
Modified Residue	Threonine	Modified Location	126
Experimental Method	Co-Immunoprecipitation
Detailed Description	Phosphorylation at SLC25A5 Threonine 126 has the potential to affect its expression or activity.
PTM Phenomenon6	Have the potential to influence SLC25A5			[40], [42]
Role of PTM	Potential impacts
Modified Residue	Threonine	Modified Location	139
Experimental Method	Co-Immunoprecipitation
Detailed Description	Phosphorylation at SLC25A5 Threonine 139 has the potential to affect its expression or activity.
PTM Phenomenon7	Have the potential to influence SLC25A5			[27], [43]
Role of PTM	Potential impacts
Modified Residue	Threonine	Modified Location	197
Experimental Method	Co-Immunoprecipitation
Detailed Description	Phosphorylation at SLC25A5 Threonine 197 has the potential to affect its expression or activity.
PTM Phenomenon8	Have the potential to influence SLC25A5			[27], [44]
Role of PTM	Potential impacts
Modified Residue	Threonine	Modified Location	247
Experimental Method	Co-Immunoprecipitation
Detailed Description	Phosphorylation at SLC25A5 Threonine 247 has the potential to affect its expression or activity.
PTM Phenomenon9	Have the potential to influence SLC25A5			[44]
Role of PTM	Potential impacts
Modified Residue	Threonine	Modified Location	254
Experimental Method	Co-Immunoprecipitation
Detailed Description	Phosphorylation at SLC25A5 Threonine 254 has the potential to affect its expression or activity.
Tyrosine	7 PTM Phenomena Related to This Residue		Click to Show/Hide the Full List
PTM Phenomenon1	Have the potential to influence SLC25A5			[45]
Role of PTM	Potential impacts
Modified Residue	Tyrosine	Modified Location	51
Experimental Method	Co-Immunoprecipitation
Detailed Description	Phosphorylation at SLC25A5 Tyrosine 51 has the potential to affect its expression or activity.
PTM Phenomenon2	Have the potential to influence SLC25A5			[27], [46]
Role of PTM	Potential impacts
Modified Residue	Tyrosine	Modified Location	81
Experimental Method	Co-Immunoprecipitation
Detailed Description	Phosphorylation at SLC25A5 Tyrosine 81 has the potential to affect its expression or activity.
PTM Phenomenon3	Have the potential to influence SLC25A5			[25], [27]
Role of PTM	Potential impacts
Modified Residue	Tyrosine	Modified Location	112
Experimental Method	Co-Immunoprecipitation
Detailed Description	Phosphorylation at SLC25A5 Tyrosine 112 has the potential to affect its expression or activity.
PTM Phenomenon4	Have the potential to influence SLC25A5			[34], [45]
Role of PTM	Potential impacts
Modified Residue	Tyrosine	Modified Location	165
Experimental Method	Co-Immunoprecipitation
Detailed Description	Phosphorylation at SLC25A5 Tyrosine 165 has the potential to affect its expression or activity.
PTM Phenomenon5	Have the potential to influence SLC25A5			[27], [47]
Role of PTM	Potential impacts
Modified Residue	Tyrosine	Modified Location	191
Experimental Method	Co-Immunoprecipitation
Detailed Description	Phosphorylation at SLC25A5 Tyrosine 191 has the potential to affect its expression or activity.
PTM Phenomenon6	Have the potential to influence SLC25A5			[27], [45]
Role of PTM	Potential impacts
Modified Residue	Tyrosine	Modified Location	195
Experimental Method	Co-Immunoprecipitation
Detailed Description	Phosphorylation at SLC25A5 Tyrosine 195 has the potential to affect its expression or activity.
PTM Phenomenon7	Have the potential to influence SLC25A5			[45]
Role of PTM	Potential impacts
Modified Residue	Tyrosine	Modified Location	251
Experimental Method	Co-Immunoprecipitation
Detailed Description	Phosphorylation at SLC25A5 Tyrosine 251 has the potential to affect its expression or activity.
S-glutathionylation
Cystine	1 PTM Phenomena Related to This Residue		Click to Show/Hide the Full List
PTM Phenomenon1	Have the potential to influence SLC25A5			[48]
Role of PTM	Potential impacts
Modified Residue	Cystine	Modified Location	257
Experimental Method	Co-Immunoprecipitation
Detailed Description	S-glutathionylation (-SSG) at SLC25A5 Cystine 257 has the potential to affect its expression or activity.
S-nitrosylation
Cysteine	1 PTM Phenomena Related to This Residue		Click to Show/Hide the Full List
PTM Phenomenon1	Have the potential to influence SLC25A5			[49]
Role of PTM	Potential impacts
Modified Residue	Cysteine
Experimental Method	Co-Immunoprecipitation
Detailed Description	S-nitrosylation at SLC25A5 Cysteine has the potential to affect its expression or activity.
Cystine	3 PTM Phenomena Related to This Residue		Click to Show/Hide the Full List
PTM Phenomenon1	Have the potential to influence SLC25A5			[49], [50]
Role of PTM	Potential impacts
Modified Residue	Cystine	Modified Location	129
Experimental Method	Co-Immunoprecipitation
Detailed Description	S-nitrosylation (-SNO) at SLC25A5 Cystine 129 has the potential to affect its expression or activity.
PTM Phenomenon2	Have the potential to influence SLC25A5			[49], [51]
Role of PTM	Potential impacts
Modified Residue	Cystine	Modified Location	160
Experimental Method	Co-Immunoprecipitation
Detailed Description	S-nitrosylation (-SNO) at SLC25A5 Cystine 160 has the potential to affect its expression or activity.
PTM Phenomenon3	Have the potential to influence SLC25A5			[50], [52]
Role of PTM	Potential impacts
Modified Residue	Cystine	Modified Location	257
Experimental Method	Co-Immunoprecipitation
Detailed Description	S-nitrosylation (-SNO) at SLC25A5 Cystine 257 has the potential to affect its expression or activity.
S-palmitoylation
Cystine	1 PTM Phenomena Related to This Residue		Click to Show/Hide the Full List
PTM Phenomenon1	Have the potential to influence SLC25A5			[53]
Role of PTM	Potential impacts
Modified Residue	Cystine	Modified Location	160
Experimental Method	Co-Immunoprecipitation
Detailed Description	S-palmitoylation at SLC25A5 Cystine 160 has the potential to affect its expression or activity.
S-sulfhydration
Cystine	3 PTM Phenomena Related to This Residue		Click to Show/Hide the Full List
PTM Phenomenon1	Have the potential to influence SLC25A5			[54]
Role of PTM	Potential impacts
Modified Residue	Cystine	Modified Location	57
Experimental Method	Co-Immunoprecipitation
Detailed Description	S-sulfhydration (-SSH) at SLC25A5 Cystine 57 has the potential to affect its expression or activity.
PTM Phenomenon2	Have the potential to influence SLC25A5			[54], [55]
Role of PTM	Potential impacts
Modified Residue	Cystine	Modified Location	160
Experimental Method	Co-Immunoprecipitation
Detailed Description	S-sulfhydration (-SSH) at SLC25A5 Cystine 160 has the potential to affect its expression or activity.
PTM Phenomenon3	Have the potential to influence SLC25A5			[55]
Role of PTM	Potential impacts
Modified Residue	Cystine	Modified Location	257
Experimental Method	Co-Immunoprecipitation
Detailed Description	S-sulfhydration (-SSH) at SLC25A5 Cystine 257 has the potential to affect its expression or activity.
Succinylation
Lysine	2 PTM Phenomena Related to This Residue		Click to Show/Hide the Full List
PTM Phenomenon1	Have the potential to influence SLC25A5			[56]
Role of PTM	Potential impacts
Modified Residue	Lysine	Modified Location	43
Experimental Method	Co-Immunoprecipitation
Detailed Description	Succinylation at SLC25A5 Lysine 43 has the potential to affect its expression or activity.
PTM Phenomenon2	Have the potential to influence SLC25A5			[56]
Role of PTM	Potential impacts
Modified Residue	Lysine	Modified Location	268
Experimental Method	Co-Immunoprecipitation
Detailed Description	Succinylation at SLC25A5 Lysine 268 has the potential to affect its expression or activity.
Sulfoxidation
Methionine	3 PTM Phenomena Related to This Residue		Click to Show/Hide the Full List
PTM Phenomenon1	Have the potential to influence SLC25A5			[57], [58]
Role of PTM	Potential impacts
Modified Residue	Methionine	Modified Location	1
Experimental Method	Co-Immunoprecipitation
Detailed Description	Sulfoxidation at SLC25A5 Methionine 1 has the potential to affect its expression or activity.
PTM Phenomenon2	Have the potential to influence SLC25A5			[57]
Role of PTM	Potential impacts
Modified Residue	Methionine	Modified Location	215
Experimental Method	Co-Immunoprecipitation
Detailed Description	Sulfoxidation at SLC25A5 Methionine 215 has the potential to affect its expression or activity.
PTM Phenomenon3	Have the potential to influence SLC25A5			[57]
Role of PTM	Potential impacts
Modified Residue	Methionine	Modified Location	282
Experimental Method	Co-Immunoprecipitation
Detailed Description	Sulfoxidation at SLC25A5 Methionine 282 has the potential to affect its expression or activity.
SUMOylation
Lysine	1 PTM Phenomena Related to This Residue		Click to Show/Hide the Full List
PTM Phenomenon1	Have the potential to influence SLC25A5			[8]
Role of PTM	Potential impacts
Modified Residue	Lysine	Modified Location	199
Experimental Method	Co-Immunoprecipitation
Detailed Description	Sumoylation at SLC25A5 Lysine 199 has the potential to affect its expression or activity.
Ubiquitination
Lysine	16 PTM Phenomena Related to This Residue		Click to Show/Hide the Full List
PTM Phenomenon1	Have the potential to influence SLC25A5			[59], [60]
Role of PTM	Potential impacts
Modified Residue	Lysine	Modified Location	10
Experimental Method	Co-Immunoprecipitation
Detailed Description	Ubiquitination at SLC25A5 Lysine 10 has the potential to affect its expression or activity.
PTM Phenomenon2	Have the potential to influence SLC25A5			[8], [61]
Role of PTM	Potential impacts
Modified Residue	Lysine	Modified Location	23
Experimental Method	Co-Immunoprecipitation
Detailed Description	Ubiquitination at SLC25A5 Lysine 23 has the potential to affect its expression or activity.
PTM Phenomenon3	Have the potential to influence SLC25A5			[61]
Role of PTM	Potential impacts
Modified Residue	Lysine	Modified Location	33
Experimental Method	Co-Immunoprecipitation
Detailed Description	Ubiquitination at SLC25A5 Lysine 33 has the potential to affect its expression or activity.
PTM Phenomenon4	Have the potential to influence SLC25A5			[61]
Role of PTM	Potential impacts
Modified Residue	Lysine	Modified Location	43
Experimental Method	Co-Immunoprecipitation
Detailed Description	Ubiquitination at SLC25A5 Lysine 43 has the potential to affect its expression or activity.
PTM Phenomenon5	Have the potential to influence SLC25A5			[59], [60]
Role of PTM	Potential impacts
Modified Residue	Lysine	Modified Location	63
Experimental Method	Co-Immunoprecipitation
Detailed Description	Ubiquitination at SLC25A5 Lysine 63 has the potential to affect its expression or activity.
PTM Phenomenon6	Have the potential to influence SLC25A5			[8], [61]
Role of PTM	Potential impacts
Modified Residue	Lysine	Modified Location	92
Experimental Method	Co-Immunoprecipitation
Detailed Description	Ubiquitination at SLC25A5 Lysine 92 has the potential to affect its expression or activity.
PTM Phenomenon7	Have the potential to influence SLC25A5			[8], [61]
Role of PTM	Potential impacts
Modified Residue	Lysine	Modified Location	96
Experimental Method	Co-Immunoprecipitation
Detailed Description	Ubiquitination at SLC25A5 Lysine 96 has the potential to affect its expression or activity.
PTM Phenomenon8	Have the potential to influence SLC25A5			[8], [61]
Role of PTM	Potential impacts
Modified Residue	Lysine	Modified Location	105
Experimental Method	Co-Immunoprecipitation
Detailed Description	Ubiquitination at SLC25A5 Lysine 105 has the potential to affect its expression or activity.
PTM Phenomenon9	Have the potential to influence SLC25A5			[61]
Role of PTM	Potential impacts
Modified Residue	Lysine	Modified Location	147
Experimental Method	Co-Immunoprecipitation
Detailed Description	Ubiquitination at SLC25A5 Lysine 147 has the potential to affect its expression or activity.
PTM Phenomenon10	Have the potential to influence SLC25A5			[8], [61]
Role of PTM	Potential impacts
Modified Residue	Lysine	Modified Location	163
Experimental Method	Co-Immunoprecipitation
Detailed Description	Ubiquitination at SLC25A5 Lysine 163 has the potential to affect its expression or activity.
PTM Phenomenon11	Have the potential to influence SLC25A5			[61]
Role of PTM	Potential impacts
Modified Residue	Lysine	Modified Location	166
Experimental Method	Co-Immunoprecipitation
Detailed Description	Ubiquitination at SLC25A5 Lysine 166 has the potential to affect its expression or activity.
PTM Phenomenon12	Have the potential to influence SLC25A5			[8], [61]
Role of PTM	Potential impacts
Modified Residue	Lysine	Modified Location	199
Experimental Method	Co-Immunoprecipitation
Detailed Description	Ubiquitination at SLC25A5 Lysine 199 has the potential to affect its expression or activity.
PTM Phenomenon13	Have the potential to influence SLC25A5			[61], [62]
Role of PTM	Potential impacts
Modified Residue	Lysine	Modified Location	245
Experimental Method	Co-Immunoprecipitation
Detailed Description	Ubiquitination at SLC25A5 Lysine 245 has the potential to affect its expression or activity.
PTM Phenomenon14	Have the potential to influence SLC25A5			[8]
Role of PTM	Potential impacts
Modified Residue	Lysine	Modified Location	268
Experimental Method	Co-Immunoprecipitation
Detailed Description	Ubiquitination at SLC25A5 Lysine 268 has the potential to affect its expression or activity.
PTM Phenomenon15	Have the potential to influence SLC25A5			[8], [61]
Role of PTM	Potential impacts
Modified Residue	Lysine	Modified Location	272
Experimental Method	Co-Immunoprecipitation
Detailed Description	Ubiquitination at SLC25A5 Lysine 272 has the potential to affect its expression or activity.
PTM Phenomenon16	Have the potential to influence SLC25A5			[59], [60]
Role of PTM	Potential impacts
Modified Residue	Lysine	Modified Location	295
Experimental Method	Co-Immunoprecipitation
Detailed Description	Ubiquitination at SLC25A5 Lysine 295 has the potential to affect its expression or activity.

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