Drug Transporter (DT) Information

General Information of DT
DT ID DTD0243
Gene Name SLC27A6
Protein Name Long-chain fatty acid transport protein 6
Gene ID
28965
UniProt ID
Q9Y2P4
TCDB ID
4.C.1.1.11
3D Structure

Modelled DT Structure

Method: multi-sequence alignment based machine learning

Detail: Structure Info

Synonyms ACSVL2; FACVL2; FATP-6; FATP6; Fatty acid transport protein 6; Fatty-acid-coenzyme A ligase, very long-chain 2; SLC27A6; Solute carrier family 27 member 6; VLCS-H1; VLCSH1; Very long-chain acyl-CoA synthetase homolog 1; hVLCS-H1
DT Family Fatty Acid Transporter (FAT) Family ;
Tissue Specificity Strongly expressed in heart and localizes tocardiac myocytes. Expressed at moderate levels in placenta,testis, and adrenal glands. Expressed at very low levels inkidney, bladder and uterus.
Function This transporter mediates the transport of long chain fatty acids (LFCA) through plasma membrane. It is believed to be the major fatty acid protein transporter in the heart.
Endogenous Substrate(s) Fatty acids
Variability Data of This Drug Transporter (DT)

Regulatory Variability Data of This DT (VARIDT 4.0)

(α) Tissue Distribution Level of Long-chain fatty acid transport protein 6
Tissue Distribution Level (TD)

(β) Cell Distribution Level of Long-chain fatty acid transport protein 6
Cell Distribution Level (CD)

(γ) Organelle Distribution Level of Long-chain fatty acid transport protein 6
Organelle Distribution Level (Subc)

Regulatory Variability Data of This DT

(β) Post-translational Modification of Long-chain fatty acid transport protein 6
Post-translational Modification (PTM)

(γ) Transcriptional Regulation of Long-chain fatty acid transport protein 6
Transcriptional Regulation (TSR)

(δ) Epigenetic Regulation of Long-chain fatty acid transport protein 6
Epigenetic Regulation (EGR)

(ε) Exogenous Modulation of Long-chain fatty acid transport protein 6
Exogenous Modulation (EGM)

General Variability Data of This DT

(α) Genetic Polymorphisms of Long-chain fatty acid transport protein 6
Genetic Polymorphisms of This DT (GPD)

(β) Disease-specific Protein Abundances of Long-chain fatty acid transport protein 6
Disease-specific Protein Abundances of This DT (DPAD)

(γ) Species- and Tissue-specific DT Abundances
Species/Tissue-specific Protein Abundances of This DT (S/TPAD)

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