| General Information of DT | |||||
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| DT ID | DTD0202 | ||||
| Gene Name | SLC25A4 | ||||
| Protein Name | Adenine nucleotide translocator 1 | ||||
| Gene ID | |||||
| UniProt ID | |||||
| TCDB ID | |||||
| 3D Structure |
Modelled DT Structure Method:homology modeling Template PDB:1OKC_A Identity:96.284% Minimized Score:-827.374 kcal/mol Detail: Structure Info |
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| Synonyms | AAC1; ADP,ATP carrier protein 1; ADP,ATP carrier protein, heart/skeletal muscle isoform T1; ANT; ANT 1; ANT1; ADP/ATP translocase 1; MTDPS12; MTDPS12A; PEO2; PEO3; PEOA2; SLC25A4; Solute carrier family 25 member 4; T1 | ||||
| DT Family | Mitochondrial Carrier (MC) Family ; | ||||
| Function | This transporter mediates mitochondrial ADP/ATP transport. Catalyzes the exchange of cytoplasmic ADP and mitochondrial adenosine triphosphate through mitochondrial inner membrane. | ||||
| Endogenous Substrate(s) | ATP; ADP | ||||
| Variability Data of This Drug Transporter (DT) | |||||
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Regulatory Variability Data of This DT (VARIDT 4.0) |
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(α) Tissue Distribution Level of Adenine nucleotide translocator 1 |
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(β) Cell Distribution Level of Adenine nucleotide translocator 1 |
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(γ) Organelle Distribution Level of Adenine nucleotide translocator 1 |
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Regulatory Variability Data of This DT |
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(β) Post-translational Modification of Adenine nucleotide translocator 1 |
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(γ) Transcriptional Regulation of Adenine nucleotide translocator 1 |
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(δ) Epigenetic Regulation of Adenine nucleotide translocator 1 |
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(ε) Exogenous Modulation of Adenine nucleotide translocator 1 |
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Structural Variability Data of This DT |
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(β) Inter-species Structural Differences |
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General Variability Data of This DT |
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(α) Genetic Polymorphisms of Adenine nucleotide translocator 1 |
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(β) Disease-specific Protein Abundances of Adenine nucleotide translocator 1 |
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(γ) Species- and Tissue-specific DT Abundances |
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