| General Information of DT | |||||
|---|---|---|---|---|---|
| DT ID | DTD0092 | ||||
| Gene Name | SLC13A2 | ||||
| Protein Name | Sodium/dicarboxylate cotransporter 1 | ||||
| Gene ID | |||||
| UniProt ID | |||||
| TCDB ID | |||||
| 3D Structure |
Modelled DT Structure Method:homology modeling Template PDB:5UL7_A; 5ULD_A Identity:35.772%;34.17% Minimized Score:-948.261 kcal/mol Detail: Structure Info |
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| Synonyms | NADC1; Na(+)/dicarboxylate cotransporter 1; NaDC-1; SDCT1; SLC13A2; Solute carrier family 13 member 2; Renal sodium/dicarboxylate cotransporter | ||||
| DT Family | Divalent Anion:Na(+) Symporter (DASS) Family ; | ||||
| Function | This cotransport mediates the transporter of sodium ions and dicarboxylates, such as succinate and citrate. | ||||
| Endogenous Substrate(s) | Citrate; Na+; Dicarboxylates | ||||
| Variability Data of This Drug Transporter (DT) | |||||
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Regulatory Variability Data of This DT (VARIDT 4.0) |
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(α) Tissue Distribution Level of Sodium/dicarboxylate cotransporter 1 |
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(β) Cell Distribution Level of Sodium/dicarboxylate cotransporter 1 |
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(γ) Organelle Distribution Level of Sodium/dicarboxylate cotransporter 1 |
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Regulatory Variability Data of This DT |
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(α) Microbiota Influence of Sodium/dicarboxylate cotransporter 1 |
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(β) Post-translational Modification of Sodium/dicarboxylate cotransporter 1 |
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(γ) Transcriptional Regulation of Sodium/dicarboxylate cotransporter 1 |
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(δ) Epigenetic Regulation of Sodium/dicarboxylate cotransporter 1 |
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(ε) Exogenous Modulation of Sodium/dicarboxylate cotransporter 1 |
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Structural Variability Data of This DT |
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(β) Inter-species Structural Differences |
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General Variability Data of This DT |
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(α) Genetic Polymorphisms of Sodium/dicarboxylate cotransporter 1 |
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(β) Disease-specific Protein Abundances of Sodium/dicarboxylate cotransporter 1 |
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(γ) Species- and Tissue-specific DT Abundances |
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