General Information of Drug Transporter (DT)
DT ID	DTD0092 Transporter Info
Gene Name	SLC13A2
Transporter Name	Sodium/dicarboxylate cotransporter 1
Gene ID	9058
UniProt ID	Q13183
Modelled Structures of This DT
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Detail Information of Structural Model
Method	Homology modeling
Template PDB	5UL7_A; 5ULD_A		Identity	35.772; 34.17%
Ramachandran Plot
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	Ramz Z Score	-2.06 ±0.34
	Residues in Favored Region	482	Ramachandran favored	94.14%
	Number of Outliers	4	Ramachandran outliers	0.78%
Local Quality
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	QMEANBrane Score		0.76
AlphaFold Protein Structure Database	Q13183 Click to jump to the details page
SWISS-MODEL Database	Q13183 Click to jump to the details page
Experimental Structures of This DT
PDB ID	Scanning Method	Resolution	Expression System	Details	Ref
8W6C	EM	2.7 Å	Homo sapiens	Click to Show/Hide the Details	[1]
Structure
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Corresponding chain	A/B
Sequence Length	605		Mutation	No
8W6D	EM	2.5 Å	Homo sapiens	Click to Show/Hide the Details	[1]
Structure
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Corresponding chain	A/B
Sequence Length	605		Mutation	No
8W6G	EM	3.3 Å	Homo sapiens	Click to Show/Hide the Details	[1]
Structure
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Corresponding chain	A/B
Sequence Length	605		Mutation	No
References
1	Cryo-EM structures of the human NaS1 and NaDC1 transporters revealed the elevator transport and allosteric regulation mechanism. Sci Adv. 2024;10(13):eadl3685.

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