| General Information of DT | |||||
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| DT ID | DTD0053 | ||||
| Gene Name | ABCB7 | ||||
| Protein Name | ABC transporter 7 protein | ||||
| Gene ID | |||||
| UniProt ID | |||||
| TCDB ID | |||||
| 3D Structure |
Modelled DT Structure Method:homology modeling Template PDB:4MYC_A Identity:50.085% Minimized Score:-1453.668 kcal/mol Detail: Structure Info |
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| Synonyms | ATP-binding cassette sub-family B member 7, mitochondrial; ABC7; ABCB7; ASAT; ATP-binding cassette transporter 7; Atm1p; EST140535 | ||||
| DT Family | ATP-Binding Cassette (ABC) Superfamily ; | ||||
| Function | This transporter mediates the transport of heme from the mitochondria to the cytosol. | ||||
| Endogenous Substrate(s) | Fe2+; FeS-glutathione; FeS-proteoliposome | ||||
| Variability Data of This Drug Transporter (DT) | |||||
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Regulatory Variability Data of This DT (VARIDT 4.0) |
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(α) Tissue Distribution Level of ABC transporter 7 protein |
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(β) Cell Distribution Level of ABC transporter 7 protein |
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(γ) Organelle Distribution Level of ABC transporter 7 protein |
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Regulatory Variability Data of This DT |
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(β) Post-translational Modification of ABC transporter 7 protein |
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(γ) Transcriptional Regulation of ABC transporter 7 protein |
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(δ) Epigenetic Regulation of ABC transporter 7 protein |
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(ε) Exogenous Modulation of ABC transporter 7 protein |
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Structural Variability Data of This DT |
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(β) Inter-species Structural Differences |
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General Variability Data of This DT |
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(α) Genetic Polymorphisms of ABC transporter 7 protein |
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(β) Disease-specific Protein Abundances of ABC transporter 7 protein |
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(γ) Species- and Tissue-specific DT Abundances |
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