General Information of Drug Transporter (DT)
DT ID DTD0118 Transporter Info
Gene Name SLC17A5
Transporter Name Vesicular H(+)/Aspartate-glutamate cotransporter
Gene ID
26503
UniProt ID
Q9NRA2

Transcriptional Regulation of This DT (TSR)

TF Superclass1: Basic domains

      Class1.1: Basic leucine zipper factors

Click to Show/Hide the Full List of 7 TF(s) Regulating This DT

        CEBPA 

Click to Show/Hide to Show 1 Transcriptional Phenomena      

       Transcriptional Phenomenon1

Direct binding to SLC17A5 gene [1]

TF Protein Name

CCAAT/enhancer-binding protein alpha Transcription Factor Info

Tissue

Embryo

Related DT Changes

Direct regulating

Experiment method

TF-transporter regulations were collected from ChIP-Seq datasets.

Detailed Description

CCAAT/enhancer-binding protein alpha (CEBPA) can directly bind to the SLC17A5 gene, which in turn affects the expression or function of the drug transporter Vesicular H(+)/Aspartate-glutamate cotransporter.

        CEBPB 

Click to Show/Hide to Show 1 Transcriptional Phenomena      

       Transcriptional Phenomenon1

Direct binding to SLC17A5 gene [2]

TF Protein Name

CCAAT/enhancer-binding protein beta Transcription Factor Info

Tissue

Blood

Related DT Changes

Direct regulating

Experiment method

TF-transporter regulations were collected from ChIP-Seq datasets.

Detailed Description

CCAAT/enhancer-binding protein beta (CEBPB) can directly bind to the SLC17A5 gene, which in turn affects the expression or function of the drug transporter Vesicular H(+)/Aspartate-glutamate cotransporter.

        CEBPD 

Click to Show/Hide to Show 1 Transcriptional Phenomena      

       Transcriptional Phenomenon1

Direct binding to SLC17A5 gene [3]

TF Protein Name

CCAAT/enhancer-binding protein delta Transcription Factor Info

Tissue

Aorta

Related DT Changes

Direct regulating

Experiment method

TF-transporter regulations were collected from ChIP-Seq datasets.

Detailed Description

CCAAT/enhancer-binding protein delta (CEBPD) can directly bind to the SLC17A5 gene, which in turn affects the expression or function of the drug transporter Vesicular H(+)/Aspartate-glutamate cotransporter.

        CREB1 

Click to Show/Hide to Show 1 Transcriptional Phenomena      

       Transcriptional Phenomenon1

Direct binding to SLC17A5 gene [4]

TF Protein Name

Cyclic AMP-responsive element-binding protein 1 Transcription Factor Info

Tissue

Embryo; Liver; Uterus

Related DT Changes

Direct regulating

Experiment method

TF-transporter regulations were collected from ChIP-Seq datasets.

Detailed Description

Cyclic AMP-responsive element-binding protein 1 (CREB1) can directly bind to the SLC17A5 gene, which in turn affects the expression or function of the drug transporter Vesicular H(+)/Aspartate-glutamate cotransporter.

        FOS 

Click to Show/Hide to Show 1 Transcriptional Phenomena      

       Transcriptional Phenomenon1

Direct binding to SLC17A5 gene [1]

TF Protein Name

Protein c-Fos Transcription Factor Info

Tissue

Breast

Related DT Changes

Direct regulating

Experiment method

TF-transporter regulations were collected from ChIP-Seq datasets.

Detailed Description

Protein c-Fos (FOS) can directly bind to the SLC17A5 gene, which in turn affects the expression or function of the drug transporter Vesicular H(+)/Aspartate-glutamate cotransporter.

        JUN 

Click to Show/Hide to Show 1 Transcriptional Phenomena      

       Transcriptional Phenomenon1

Binding to SLC17A5 gene in K562 cells [5]

TF Protein Name

Transcription factor Jun Transcription Factor Info

Related DT Changes

Direct regulating

Detailed Description

Transcription factor Jun (JUN) has been reported to bind to the transcription of SLC17A5 gene in K562 cells, which leads to an affected expression of the drug transporter Vesicular H(+)/Aspartate-glutamate cotransporter.

        XBP1 

Click to Show/Hide to Show 1 Transcriptional Phenomena      

       Transcriptional Phenomenon1

Direct binding to SLC17A5 gene [2]

TF Protein Name

X-box-binding protein 1 Transcription Factor Info

Tissue

Breast

Related DT Changes

Direct regulating

Experiment method

TF-transporter regulations were collected from ChIP-Seq datasets.

Detailed Description

X-box-binding protein 1 (XBP1) can directly bind to the SLC17A5 gene, which in turn affects the expression or function of the drug transporter Vesicular H(+)/Aspartate-glutamate cotransporter.

      Class1.2: Basic helix-loop-helix factors

Click to Show/Hide the Full List of 5 TF(s) Regulating This DT

        AHR 

Click to Show/Hide to Show 1 Transcriptional Phenomena      

       Transcriptional Phenomenon1

Activation of SLC17A5 gene in breast cancer condition [6]

TF Protein Name

Aryl hydrocarbon receptor Transcription Factor Info

Affected Drug/Substrate

2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD)

Studied Phenotype

.

Related DT Changes

Up regulating

Detailed Description

Aryl hydrocarbon receptor (AHR) has been reported to activate the transcription of SLC17A5 gene in breast cancer condition, which leads to an increased expression of the drug transporter Vesicular H(+)/Aspartate-glutamate cotransporter.

        ARNT 

Click to Show/Hide to Show 1 Transcriptional Phenomena      

       Transcriptional Phenomenon1

Activation of SLC17A5 gene in breast cancer condition [6]

TF Protein Name

Aryl hydrocarbon receptor nuclear translocator Transcription Factor Info

Affected Drug/Substrate

2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD)

Studied Phenotype

.

Related DT Changes

Up regulating

Detailed Description

Aryl hydrocarbon receptor nuclear translocator (ARNT) has been reported to activate the transcription of SLC17A5 gene in breast cancer condition, which leads to an increased expression of the drug transporter Vesicular H(+)/Aspartate-glutamate cotransporter.

        ASCL1 

Click to Show/Hide to Show 1 Transcriptional Phenomena      

       Transcriptional Phenomenon1

Direct binding to SLC17A5 gene [4]

TF Protein Name

Achaete-scute homolog 1 Transcription Factor Info

Tissue

Lung

Related DT Changes

Direct regulating

Experiment method

TF-transporter regulations were collected from ChIP-Seq datasets.

Detailed Description

Achaete-scute homolog 1 (ASCL1) can directly bind to the SLC17A5 gene, which in turn affects the expression or function of the drug transporter Vesicular H(+)/Aspartate-glutamate cotransporter.

        LYL1 

Click to Show/Hide to Show 1 Transcriptional Phenomena      

       Transcriptional Phenomenon1

Direct binding to SLC17A5 gene [3]

TF Protein Name

Protein lyl-1 Transcription Factor Info

Tissue

Blood; Bone marrow; Colon

Related DT Changes

Direct regulating

Experiment method

TF-transporter regulations were collected from ChIP-Seq datasets.

Detailed Description

Protein lyl-1 (LYL1) can directly bind to the SLC17A5 gene, which in turn affects the expression or function of the drug transporter Vesicular H(+)/Aspartate-glutamate cotransporter.

        MITF 

Click to Show/Hide to Show 1 Transcriptional Phenomena      

       Transcriptional Phenomenon1

Activation of SLC17A5 gene in melanoma condition [7]

TF Protein Name

Microphthalmia-associated transcription factor Transcription Factor Info

Studied Phenotype

.

Related DT Changes

Up regulating

Detailed Description

Microphthalmia-associated transcription factor (MITF) has been reported to activate the transcription of SLC17A5 gene in melanoma condition, which leads to an increased expression of the drug transporter Vesicular H(+)/Aspartate-glutamate cotransporter.

TF Superclass2: Zinc-coordinating DNA-binding domains

      Class2.1: Nuclear receptors with C4 zinc fingers

Click to Show/Hide the Full List of 2 TF(s) Regulating This DT

        HNF4A 

Click to Show/Hide to Show 2 Transcriptional Phenomena      

       Transcriptional Phenomenon1

Binding to SLC17A5 gene in health condition [8]

TF Protein Name

Hepatocyte nuclear factor 4-alpha Transcription Factor Info

Studied Phenotype

.

Related DT Changes

Direct regulating

Detailed Description

Hepatocyte nuclear factor 4-alpha (HNF4A) has been reported to bind to the transcription of SLC17A5 gene in health condition, which leads to an affected expression of the drug transporter Vesicular H(+)/Aspartate-glutamate cotransporter.

       Transcriptional Phenomenon2

Binding to SLC17A5 gene in health condition [9]

TF Protein Name

Hepatocyte nuclear factor 4-alpha Transcription Factor Info

Studied Phenotype

.

Related DT Changes

Direct regulating

Detailed Description

Hepatocyte nuclear factor 4-alpha (HNF4A) has been reported to bind to the transcription of SLC17A5 gene in health condition, which leads to an affected expression of the drug transporter Vesicular H(+)/Aspartate-glutamate cotransporter.

        PPARD 

Click to Show/Hide to Show 1 Transcriptional Phenomena      

       Transcriptional Phenomenon1

Repression of SLC17A5 gene in myofibroblasts condition [10]

TF Protein Name

Peroxisome proliferator-activated receptor delta Transcription Factor Info

Studied Phenotype

.

Related DT Changes

Down regulating

Detailed Description

Peroxisome proliferator-activated receptor delta (PPARD) has been reported to repress the transcription of SLC17A5 gene in myofibroblasts condition, which leads to a decreased expression of the drug transporter Vesicular H(+)/Aspartate-glutamate cotransporter.

      Class2.2: Other C4 zinc finger-type factors

Click to Show/Hide the Full List of 2 TF(s) Regulating This DT

        GATA1 

Click to Show/Hide to Show 2 Transcriptional Phenomena      

       Transcriptional Phenomenon1

Binding to SLC17A5 gene in megakaryocytes condition [11]

TF Protein Name

Erythroid transcription factor Transcription Factor Info

Related DT Changes

Direct regulating

Detailed Description

Erythroid transcription factor (GATA1) has been reported to bind to the transcription of SLC17A5 gene in megakaryocytes condition, which leads to an affected expression of the drug transporter Vesicular H(+)/Aspartate-glutamate cotransporter.

       Transcriptional Phenomenon2

Direct binding to SLC17A5 gene [4]

TF Protein Name

Erythroid transcription factor Transcription Factor Info

Tissue

Blood; Bone marrow

Related DT Changes

Direct regulating

Experiment method

TF-transporter regulations were collected from ChIP-Seq datasets.

Detailed Description

Erythroid transcription factor (GATA1) can directly bind to the SLC17A5 gene, which in turn affects the expression or function of the drug transporter Vesicular H(+)/Aspartate-glutamate cotransporter.

        GATA2 

Click to Show/Hide to Show 2 Transcriptional Phenomena      

       Transcriptional Phenomenon1

Binding to SLC17A5 gene in megakaryocytes condition [11]

TF Protein Name

Endothelial transcription factor GATA-2 Transcription Factor Info

Related DT Changes

Direct regulating

Detailed Description

Endothelial transcription factor GATA-2 (GATA2) has been reported to bind to the transcription of SLC17A5 gene in megakaryocytes condition, which leads to an affected expression of the drug transporter Vesicular H(+)/Aspartate-glutamate cotransporter.

       Transcriptional Phenomenon2

Direct binding to SLC17A5 gene [1]

TF Protein Name

Endothelial transcription factor GATA-2 Transcription Factor Info

Tissue

Blood

Related DT Changes

Direct regulating

Experiment method

TF-transporter regulations were collected from ChIP-Seq datasets.

Detailed Description

Endothelial transcription factor GATA-2 (GATA2) can directly bind to the SLC17A5 gene, which in turn affects the expression or function of the drug transporter Vesicular H(+)/Aspartate-glutamate cotransporter.

      Class2.3: C2H2 zinc finger factors

Click to Show/Hide the Full List of 4 TF(s) Regulating This DT

        BCL6 

Click to Show/Hide to Show 1 Transcriptional Phenomena      

       Transcriptional Phenomenon1

Activation of SLC17A5 gene in health condition [12]

TF Protein Name

B-cell lymphoma 6 protein Transcription Factor Info

Studied Phenotype

.

Related DT Changes

Up regulating

Detailed Description

B-cell lymphoma 6 protein (BCL6) has been reported to activate the transcription of SLC17A5 gene in health condition, which leads to an increased expression of the drug transporter Vesicular H(+)/Aspartate-glutamate cotransporter.

        CTCF 

Click to Show/Hide to Show 1 Transcriptional Phenomena      

       Transcriptional Phenomenon1

Direct binding to SLC17A5 gene [3]

TF Protein Name

Transcriptional repressor CTCF Transcription Factor Info

Tissue

Brain

Related DT Changes

Direct regulating

Experiment method

TF-transporter regulations were collected from ChIP-Seq datasets.

Detailed Description

Transcriptional repressor CTCF (CTCF) can directly bind to the SLC17A5 gene, which in turn affects the expression or function of the drug transporter Vesicular H(+)/Aspartate-glutamate cotransporter.

        EGR1 

Click to Show/Hide to Show 1 Transcriptional Phenomena      

       Transcriptional Phenomenon1

Binding to SLC17A5 gene in erythroleukemia condition [13]

TF Protein Name

Early growth response protein 1 Transcription Factor Info

Studied Phenotype

.

Related DT Changes

Direct regulating

Detailed Description

Early growth response protein 1 (EGR1) has been reported to bind to the transcription of SLC17A5 gene in erythroleukemia condition, which leads to an affected expression of the drug transporter Vesicular H(+)/Aspartate-glutamate cotransporter.

        MAZ 

Click to Show/Hide to Show 1 Transcriptional Phenomena      

       Transcriptional Phenomenon1

Direct binding to SLC17A5 gene [2]

TF Protein Name

Myc-associated zinc finger protein Transcription Factor Info

Tissue

Blood; Bone marrow; Cervix; Liver; Lung

Related DT Changes

Direct regulating

Experiment method

TF-transporter regulations were collected from ChIP-Seq datasets.

Detailed Description

Myc-associated zinc finger protein (MAZ) can directly bind to the SLC17A5 gene, which in turn affects the expression or function of the drug transporter Vesicular H(+)/Aspartate-glutamate cotransporter.

TF Superclass3: Helix-turn-helix domains

      Class3.1: Homeo domain factors

Click to Show/Hide the Full List of 1 TF(s) Regulating This DT

        PBX3 

Click to Show/Hide to Show 1 Transcriptional Phenomena      

       Transcriptional Phenomenon1

Direct binding to SLC17A5 gene [4]

TF Protein Name

Pre-B-cell leukemia transcription factor 3 Transcription Factor Info

Tissue

Blood

Related DT Changes

Direct regulating

Experiment method

TF-transporter regulations were collected from ChIP-Seq datasets.

Detailed Description

Pre-B-cell leukemia transcription factor 3 (PBX3) can directly bind to the SLC17A5 gene, which in turn affects the expression or function of the drug transporter Vesicular H(+)/Aspartate-glutamate cotransporter.

      Class3.3: Fork head / winged helix factors

Click to Show/Hide the Full List of 3 TF(s) Regulating This DT

        E2F1 

Click to Show/Hide to Show 1 Transcriptional Phenomena      

       Transcriptional Phenomenon1

Direct binding to SLC17A5 gene [4]

TF Protein Name

Transcription factor E2F1 Transcription Factor Info

Tissue

Mesenchymal

Related DT Changes

Direct regulating

Experiment method

TF-transporter regulations were collected from ChIP-Seq datasets.

Detailed Description

Transcription factor E2F1 (E2F1) can directly bind to the SLC17A5 gene, which in turn affects the expression or function of the drug transporter Vesicular H(+)/Aspartate-glutamate cotransporter.

        FOXA1 

Click to Show/Hide to Show 2 Transcriptional Phenomena      

       Transcriptional Phenomenon1

Binding to SLC17A5 gene in prostate carcinoma condition [14]

TF Protein Name

Hepatocyte nuclear factor 3-alpha Transcription Factor Info

Studied Phenotype

.

Related DT Changes

Direct regulating

Detailed Description

Hepatocyte nuclear factor 3-alpha (FOXA1) has been reported to bind to the transcription of SLC17A5 gene in prostate carcinoma condition, which leads to an affected expression of the drug transporter Vesicular H(+)/Aspartate-glutamate cotransporter.

       Transcriptional Phenomenon2

Direct binding to SLC17A5 gene [3]

TF Protein Name

Hepatocyte nuclear factor 3-alpha Transcription Factor Info

Tissue

Breast; Embryo; Liver; Pancreatic ductal; Prostate

Related DT Changes

Direct regulating

Experiment method

TF-transporter regulations were collected from ChIP-Seq datasets.

Detailed Description

Hepatocyte nuclear factor 3-alpha (FOXA1) can directly bind to the SLC17A5 gene, which in turn affects the expression or function of the drug transporter Vesicular H(+)/Aspartate-glutamate cotransporter.

        FOXA2 

Click to Show/Hide to Show 1 Transcriptional Phenomena      

       Transcriptional Phenomenon1

Direct binding to SLC17A5 gene [4]

TF Protein Name

Hepatocyte nuclear factor 3-beta Transcription Factor Info

Tissue

Embryo; Liver; Lung; Skin

Related DT Changes

Direct regulating

Experiment method

TF-transporter regulations were collected from ChIP-Seq datasets.

Detailed Description

Hepatocyte nuclear factor 3-beta (FOXA2) can directly bind to the SLC17A5 gene, which in turn affects the expression or function of the drug transporter Vesicular H(+)/Aspartate-glutamate cotransporter.

      Class3.5: Tryptophan cluster factors

Click to Show/Hide the Full List of 6 TF(s) Regulating This DT

        ERG 

Click to Show/Hide to Show 1 Transcriptional Phenomena      

       Transcriptional Phenomenon1

Direct binding to SLC17A5 gene [1]

TF Protein Name

Transcriptional regulator ERG Transcription Factor Info

Tissue

Blood

Related DT Changes

Direct regulating

Experiment method

TF-transporter regulations were collected from ChIP-Seq datasets.

Detailed Description

Transcriptional regulator ERG (ERG) can directly bind to the SLC17A5 gene, which in turn affects the expression or function of the drug transporter Vesicular H(+)/Aspartate-glutamate cotransporter.

        ETS1 

Click to Show/Hide to Show 1 Transcriptional Phenomena      

       Transcriptional Phenomenon1

Direct binding to SLC17A5 gene [2]

TF Protein Name

Protein C-ets-1 Transcription Factor Info

Tissue

Blood; Bone; Bone marrow; Kidney; Lung; Vein

Related DT Changes

Direct regulating

Experiment method

TF-transporter regulations were collected from ChIP-Seq datasets.

Detailed Description

Protein C-ets-1 (ETS1) can directly bind to the SLC17A5 gene, which in turn affects the expression or function of the drug transporter Vesicular H(+)/Aspartate-glutamate cotransporter.

        ETS2 

Click to Show/Hide to Show 1 Transcriptional Phenomena      

       Transcriptional Phenomenon1

Direct binding to SLC17A5 gene [1]

TF Protein Name

Protein C-ets-2 Transcription Factor Info

Tissue

Colon

Related DT Changes

Direct regulating

Experiment method

TF-transporter regulations were collected from ChIP-Seq datasets.

Detailed Description

Protein C-ets-2 (ETS2) can directly bind to the SLC17A5 gene, which in turn affects the expression or function of the drug transporter Vesicular H(+)/Aspartate-glutamate cotransporter.

        FLI1 

Click to Show/Hide to Show 2 Transcriptional Phenomena      

       Transcriptional Phenomenon1

Binding to SLC17A5 gene in megakaryocytes condition [11]

TF Protein Name

Friend leukemia integration 1 transcription factor Transcription Factor Info

Related DT Changes

Direct regulating

Detailed Description

Friend leukemia integration 1 transcription factor (FLI1) has been reported to bind to the transcription of SLC17A5 gene in megakaryocytes condition, which leads to an affected expression of the drug transporter Vesicular H(+)/Aspartate-glutamate cotransporter.

       Transcriptional Phenomenon2

Direct binding to SLC17A5 gene [2]

TF Protein Name

Friend leukemia integration 1 transcription factor Transcription Factor Info

Tissue

Blood; Mesenchymal

Related DT Changes

Direct regulating

Experiment method

TF-transporter regulations were collected from ChIP-Seq datasets.

Detailed Description

Friend leukemia integration 1 transcription factor (FLI1) can directly bind to the SLC17A5 gene, which in turn affects the expression or function of the drug transporter Vesicular H(+)/Aspartate-glutamate cotransporter.

        GABPA 

Click to Show/Hide to Show 1 Transcriptional Phenomena      

       Transcriptional Phenomenon1

Direct binding to SLC17A5 gene [3]

TF Protein Name

GA-binding protein alpha chain Transcription Factor Info

Tissue

Brain; Liver

Related DT Changes

Direct regulating

Experiment method

TF-transporter regulations were collected from ChIP-Seq datasets.

Detailed Description

GA-binding protein alpha chain (GABPA) can directly bind to the SLC17A5 gene, which in turn affects the expression or function of the drug transporter Vesicular H(+)/Aspartate-glutamate cotransporter.

        SPI1 

Click to Show/Hide to Show 2 Transcriptional Phenomena      

       Transcriptional Phenomenon1

Binding to SLC17A5 gene in APL condition [15]

TF Protein Name

Transcription factor PU.1 Transcription Factor Info

Studied Phenotype

.

Related DT Changes

Direct regulating

Detailed Description

Transcription factor PU.1 (SPI1) has been reported to bind to the transcription of SLC17A5 gene in acute promyelocytic leukemia (APL) condition, which leads to an affected expression of the drug transporter Vesicular H(+)/Aspartate-glutamate cotransporter.

       Transcriptional Phenomenon2

Direct binding to SLC17A5 gene [1]

TF Protein Name

Transcription factor PU.1 Transcription Factor Info

Tissue

Adrenal gland; Blood; Bone marrow; Brain; Breast; Embryo; Foreskin; Heart; Intestine; Kidney; Lung; Muscle; Penis; Placenta; Renal cortex; Renal pelvis; Skin; Spinal cord; Stomach; Testes; Umbilical cord blood

Related DT Changes

Direct regulating

Experiment method

TF-transporter regulations were collected from ChIP-Seq datasets.

Detailed Description

Transcription factor PU.1 (SPI1) can directly bind to the SLC17A5 gene, which in turn affects the expression or function of the drug transporter Vesicular H(+)/Aspartate-glutamate cotransporter.

TF Superclass4: Other all-alpha-helical DNA-binding domains

      Class4.1: High-mobility group domain factors

Click to Show/Hide the Full List of 1 TF(s) Regulating This DT

        SOX2 

Click to Show/Hide to Show 1 Transcriptional Phenomena      

       Transcriptional Phenomenon1

Activation of SLC17A5 gene in colorectal cancer condition [16]

TF Protein Name

Transcription factor SOX-2 Transcription Factor Info

Studied Phenotype

.

Related DT Changes

Up regulating

Detailed Description

Transcription factor SOX-2 (SOX2) has been reported to activate the transcription of SLC17A5 gene in colorectal cancer condition, which leads to an increased expression of the drug transporter Vesicular H(+)/Aspartate-glutamate cotransporter.

TF Superclass6: Immunoglobulin fold

      Class6.4: Runt domain factors

Click to Show/Hide the Full List of 1 TF(s) Regulating This DT

        RUNX1 

Click to Show/Hide to Show 1 Transcriptional Phenomena      

       Transcriptional Phenomenon1

Binding to SLC17A5 gene in megakaryocytes condition [11]

TF Protein Name

Runt-related transcription factor 1 Transcription Factor Info

Related DT Changes

Direct regulating

Detailed Description

Runt-related transcription factor 1 (RUNX1) has been reported to bind to the transcription of SLC17A5 gene in megakaryocytes condition, which leads to an affected expression of the drug transporter Vesicular H(+)/Aspartate-glutamate cotransporter.

TF Superclass10: Yet undefined DNA-binding domains

      Class10.1: Other factors

Click to Show/Hide the Full List of 1 TF(s) Regulating This DT

        GTF2B 

Click to Show/Hide to Show 1 Transcriptional Phenomena      

       Transcriptional Phenomenon1

Direct binding to SLC17A5 gene [2]

TF Protein Name

Transcription initiation factor IIB Transcription Factor Info

Tissue

Cervix; Lung

Related DT Changes

Direct regulating

Experiment method

TF-transporter regulations were collected from ChIP-Seq datasets.

Detailed Description

Transcription initiation factor IIB (GTF2B) can directly bind to the SLC17A5 gene, which in turn affects the expression or function of the drug transporter Vesicular H(+)/Aspartate-glutamate cotransporter.
References
1 NCBI GEO: archive for functional genomics data sets--update. Nucleic Acids Res. 2013 Jan;41(D1):D991-5.
2 Closure of the NCBI SRA and implications for the long-term future of genomics data storage. Genome Biol. 2011;12(3):402.
3 The Encyclopedia of DNA elements (ENCODE): data portal update. Nucleic Acids Res. 2018 Jan 4;46(D1):D794-D801
4 hTFtarget: A Comprehensive Database for Regulations of Human Transcription Factors and Their Targets. Genomics Proteomics Bioinformatics. 2020 Apr;18(2):120-242. (ID:ENSG00000119899)
5 c-Jun binding site identification in K562 cells. J Genet Genomics. 2011;38(6):235-42.
6 High-resolution genome-wide mapping of AHR and ARNT binding sites by ChIP-Seq. Toxicol Sci. 2012 Dec;130(2):349-61.
7 Essential role of microphthalmia transcription factor for DNA replication, mitosis and genomic stability in melanoma. Oncogene. 2011;30(20):2319-32.
8 Mapping of HNF4alpha target genes in intestinal epithelial cells. BMC Gastroenterol. 2009;9:68.
9 Molecular interactions between HNF4a, FOXA2 and GABP identified at regulatory DNA elements through ChIP-sequencing. Nucleic Acids Res. 2009;37(22):7498-508.
10 Genomewide analyses define different modes of transcriptional regulation by peroxisome proliferator-activated receptor. PLoS One. 2011;6(1):e16344.
11 Genome-wide analysis of simultaneous GATA1/2, RUNX1, FLI1, and SCL binding in megakaryocytes identifies hematopoietic regulators. Dev Cell. 2011;20(5):597-609.
12 The transcriptional regulator BCL6 participates in the secondary gene regulatory response to vitamin D. Biochim Biophys Acta. 2015;1849(3):300-8.
13 Global analysis of in vivo EGR1-binding sites in erythroleukemia cell using chromatin immunoprecipitation and massively parallel sequencing. Electrophoresis. 2010;31(17):2936-43.
14 SUMO ligase PIAS1 functions as a target gene selective androgen receptor coregulator on prostate cancer cell chromatin. Nucleic Acids Res. 2015;43(2):848-61.
15 Structurally differentiated cis-elements that interact with PU.1 are functionally distinguishable in acute promyelocytic leukemia. J Hematol Oncol. 2013;6:25.
16 ChIP-seq and functional analysis of the SOX2 gene in colorectal cancers. OMICS. 2010;14(4):369-84.

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