General Information of Drug Transporter (DT)
DT ID DTD0542 Transporter Info
Gene Name ANXA2
Transporter Name Annexin A2
Gene ID
302
UniProt ID
P07355

Transcriptional Regulation of This DT (TSR)

TF Superclass1: Basic domains

      Class1.1: Basic leucine zipper factors

Click to Show/Hide the Full List of 9 TF(s) Regulating This DT

        ATF3 

Click to Show/Hide to Show 1 Transcriptional Phenomena      

       Transcriptional Phenomenon1

Repression of ANXA2 gene in glioblastoma multiforme condition [1]

TF Protein Name

Cyclic AMP-dependent transcription factor ATF-3 Transcription Factor Info

Studied Phenotype

.

Related DT Changes

Down regulating

Detailed Description

Cyclic AMP-dependent transcription factor ATF-3 (ATF3) has been reported to repress the transcription of ANXA2 gene in glioblastoma multiforme condition, which leads to a decreased expression of the drug transporter Annexin A2.

        CEBPA 

Click to Show/Hide to Show 1 Transcriptional Phenomena      

       Transcriptional Phenomenon1

Direct binding to ANXA2 gene [2]

TF Protein Name

CCAAT/enhancer-binding protein alpha Transcription Factor Info

Tissue

Blood

Related DT Changes

Direct regulating

Experiment method

TF-transporter regulations were collected from ChIP-Seq datasets.

Detailed Description

CCAAT/enhancer-binding protein alpha (CEBPA) can directly bind to the ANXA2 gene, which in turn affects the expression or function of the drug transporter Annexin A2.

        CEBPD 

Click to Show/Hide to Show 1 Transcriptional Phenomena      

       Transcriptional Phenomenon1

Direct binding to ANXA2 gene [3]

TF Protein Name

CCAAT/enhancer-binding protein delta Transcription Factor Info

Tissue

Aorta

Related DT Changes

Direct regulating

Experiment method

TF-transporter regulations were collected from ChIP-Seq datasets.

Detailed Description

CCAAT/enhancer-binding protein delta (CEBPD) can directly bind to the ANXA2 gene, which in turn affects the expression or function of the drug transporter Annexin A2.

        CREB1 

Click to Show/Hide to Show 1 Transcriptional Phenomena      

       Transcriptional Phenomenon1

Direct binding to ANXA2 gene [4]

TF Protein Name

Cyclic AMP-responsive element-binding protein 1 Transcription Factor Info

Tissue

Breast; Liver

Related DT Changes

Direct regulating

Experiment method

TF-transporter regulations were collected from ChIP-Seq datasets.

Detailed Description

Cyclic AMP-responsive element-binding protein 1 (CREB1) can directly bind to the ANXA2 gene, which in turn affects the expression or function of the drug transporter Annexin A2.

        FOSL1 

Click to Show/Hide to Show 1 Transcriptional Phenomena      

       Transcriptional Phenomenon1

Direct binding to ANXA2 gene [5]

TF Protein Name

Fos-related antigen 1 Transcription Factor Info

Tissue

Bone marrow; Breast; Colon

Related DT Changes

Direct regulating

Experiment method

TF-transporter regulations were collected from ChIP-Seq datasets.

Detailed Description

Fos-related antigen 1 (FOSL1) can directly bind to the ANXA2 gene, which in turn affects the expression or function of the drug transporter Annexin A2.

        FOSL2 

Click to Show/Hide to Show 1 Transcriptional Phenomena      

       Transcriptional Phenomenon1

Direct binding to ANXA2 gene [5]

TF Protein Name

Fos-related antigen 2 Transcription Factor Info

Tissue

Brain; Breast; Liver; Lung

Related DT Changes

Direct regulating

Experiment method

TF-transporter regulations were collected from ChIP-Seq datasets.

Detailed Description

Fos-related antigen 2 (FOSL2) can directly bind to the ANXA2 gene, which in turn affects the expression or function of the drug transporter Annexin A2.

        JUN 

Click to Show/Hide to Show 1 Transcriptional Phenomena      

       Transcriptional Phenomenon1

Direct binding to ANXA2 gene in coronary artery disease condition [6]

TF Protein Name

Transcription factor Jun Transcription Factor Info

Studied Phenotype

.

Related DT Changes

Direct regulating

Detailed Description

Transcription factor Jun (JUN) has been reported to bind to the ANXA2 gene in coronary artery disease condition, which affects the expression or function of the drug transporter Annexin A2.

        JUNB 

Click to Show/Hide to Show 1 Transcriptional Phenomena      

       Transcriptional Phenomenon1

Direct binding to ANXA2 gene [2]

TF Protein Name

Transcription factor JunB Transcription Factor Info

Tissue

Aorta

Related DT Changes

Direct regulating

Experiment method

TF-transporter regulations were collected from ChIP-Seq datasets.

Detailed Description

Transcription factor JunB (JUNB) can directly bind to the ANXA2 gene, which in turn affects the expression or function of the drug transporter Annexin A2.

        JUND 

Click to Show/Hide to Show 1 Transcriptional Phenomena      

       Transcriptional Phenomenon1

Direct binding to ANXA2 gene [3]

TF Protein Name

Transcription factor JunD Transcription Factor Info

Tissue

Bone

Related DT Changes

Direct regulating

Experiment method

TF-transporter regulations were collected from ChIP-Seq datasets.

Detailed Description

Transcription factor JunD (JUND) can directly bind to the ANXA2 gene, which in turn affects the expression or function of the drug transporter Annexin A2.

      Class1.2: Basic helix-loop-helix factors

Click to Show/Hide the Full List of 10 TF(s) Regulating This DT

        ARNT 

Click to Show/Hide to Show 1 Transcriptional Phenomena      

       Transcriptional Phenomenon1

Direct binding to ANXA2 gene [4]

TF Protein Name

Aryl hydrocarbon receptor nuclear translocator Transcription Factor Info

Tissue

Breast

Related DT Changes

Direct regulating

Experiment method

TF-transporter regulations were collected from ChIP-Seq datasets.

Detailed Description

Aryl hydrocarbon receptor nuclear translocator (ARNT) can directly bind to the ANXA2 gene, which in turn affects the expression or function of the drug transporter Annexin A2.

        ASCL1 

Click to Show/Hide to Show 1 Transcriptional Phenomena      

       Transcriptional Phenomenon1

Direct binding to ANXA2 gene [5]

TF Protein Name

Achaete-scute homolog 1 Transcription Factor Info

Tissue

Lung

Related DT Changes

Direct regulating

Experiment method

TF-transporter regulations were collected from ChIP-Seq datasets.

Detailed Description

Achaete-scute homolog 1 (ASCL1) can directly bind to the ANXA2 gene, which in turn affects the expression or function of the drug transporter Annexin A2.

        ASCL2 

Click to Show/Hide to Show 1 Transcriptional Phenomena      

       Transcriptional Phenomenon1

Direct binding to ANXA2 gene [4]

TF Protein Name

Achaete-scute homolog 2 Transcription Factor Info

Tissue

Colon; Prostate

Related DT Changes

Direct regulating

Experiment method

TF-transporter regulations were collected from ChIP-Seq datasets.

Detailed Description

Achaete-scute homolog 2 (ASCL2) can directly bind to the ANXA2 gene, which in turn affects the expression or function of the drug transporter Annexin A2.

        CLOCK 

Click to Show/Hide to Show 1 Transcriptional Phenomena      

       Transcriptional Phenomenon1

Activation of ANXA2 gene in microsatellite unstable colorectal cancers condition [7]

TF Protein Name

Circadian locomoter output cycles protein kaput Transcription Factor Info

Studied Phenotype

.

Related DT Changes

Up regulating

Detailed Description

Circadian locomoter output cycles protein kaput (CLOCK) has been reported to activate the transcription of ANXA2 gene in microsatellite unstable colorectal cancers condition, which leads to an affected expression of the drug transporter Annexin A2.

        MITF 

Click to Show/Hide to Show 1 Transcriptional Phenomena      

       Transcriptional Phenomenon1

Activation of ANXA2 gene in melanoma condition [8]

TF Protein Name

Microphthalmia-associated transcription factor Transcription Factor Info

Studied Phenotype

.

Related DT Changes

Up regulating

Detailed Description

Microphthalmia-associated transcription factor (MITF) has been reported to activate the transcription of ANXA2 gene in melanoma condition, which leads to an increased expression of the drug transporter Annexin A2.

        MYOD1 

Click to Show/Hide to Show 1 Transcriptional Phenomena      

       Transcriptional Phenomenon1

Direct binding to ANXA2 gene [2]

TF Protein Name

Myoblast determination protein 1 Transcription Factor Info

Tissue

Myotube

Related DT Changes

Direct regulating

Experiment method

TF-transporter regulations were collected from ChIP-Seq datasets.

Detailed Description

Myoblast determination protein 1 (MYOD1) can directly bind to the ANXA2 gene, which in turn affects the expression or function of the drug transporter Annexin A2.

        TCF12 

Click to Show/Hide to Show 1 Transcriptional Phenomena      

       Transcriptional Phenomenon1

Direct binding to ANXA2 gene [4]

TF Protein Name

Transcription factor 12 Transcription Factor Info

Tissue

Blood; Brain; Lung; Uterus

Related DT Changes

Direct regulating

Experiment method

TF-transporter regulations were collected from ChIP-Seq datasets.

Detailed Description

Transcription factor 12 (TCF12) can directly bind to the ANXA2 gene, which in turn affects the expression or function of the drug transporter Annexin A2.

        TCF21 

Click to Show/Hide to Show 2 Transcriptional Phenomena      

       Transcriptional Phenomenon1

Binding to ANXA2 gene in coronary artery disease condition [6]

TF Protein Name

Transcription factor 21 Transcription Factor Info

Studied Phenotype

.

Related DT Changes

Direct regulating

Detailed Description

Transcription factor 21 (TCF21) has been reported to bind to the ANXA2 gene in coronary artery disease condition, which affects the expression or function of the drug transporter Annexin A2.

       Transcriptional Phenomenon2

Direct binding to ANXA2 gene [3]

TF Protein Name

Transcription factor 21 Transcription Factor Info

Tissue

Coronary artery

Related DT Changes

Direct regulating

Experiment method

TF-transporter regulations were collected from ChIP-Seq datasets.

Detailed Description

Transcription factor 21 (TCF21) can directly bind to the ANXA2 gene, which in turn affects the expression or function of the drug transporter Annexin A2.

        TCF3 

Click to Show/Hide to Show 1 Transcriptional Phenomena      

       Transcriptional Phenomenon1

Direct binding to ANXA2 gene [5]

TF Protein Name

Transcription factor E2-alpha Transcription Factor Info

Tissue

Blood

Related DT Changes

Direct regulating

Experiment method

TF-transporter regulations were collected from ChIP-Seq datasets.

Detailed Description

Transcription factor E2-alpha (TCF3) can directly bind to the ANXA2 gene, which in turn affects the expression or function of the drug transporter Annexin A2.

        TCF4 

Click to Show/Hide to Show 1 Transcriptional Phenomena      

       Transcriptional Phenomenon1

Binding to ANXA2 gene in glioblastoma multiforme condition [9]

TF Protein Name

Transcription factor 4 Transcription Factor Info

Affected Drug/Substrate

Temozolomide

Studied Phenotype

.

Related DT Changes

Direct regulating

Detailed Description

Transcription factor 4 (TCF4) has been reported to bind to the transcription of ANXA2 gene in glioblastoma multiforme condition, which leads to an affected expression of the drug transporter Annexin A2.

      Class1.3: Basic helix-span-helix factors

Click to Show/Hide the Full List of 2 TF(s) Regulating This DT

        TFAP2A 

Click to Show/Hide to Show 1 Transcriptional Phenomena      

       Transcriptional Phenomenon1

Direct binding to ANXA2 gene [2]

TF Protein Name

Transcription factor AP-2-alpha Transcription Factor Info

Tissue

Breast; Cervix

Related DT Changes

Direct regulating

Experiment method

TF-transporter regulations were collected from ChIP-Seq datasets.

Detailed Description

Transcription factor AP-2-alpha (TFAP2A) can directly bind to the ANXA2 gene, which in turn affects the expression or function of the drug transporter Annexin A2.

        TFAP2C 

Click to Show/Hide to Show 1 Transcriptional Phenomena      

       Transcriptional Phenomenon1

Direct binding to ANXA2 gene [3]

TF Protein Name

Transcription factor AP-2 gamma Transcription Factor Info

Tissue

Breast; Cervix; Skin

Related DT Changes

Direct regulating

Experiment method

TF-transporter regulations were collected from ChIP-Seq datasets.

Detailed Description

Transcription factor AP-2 gamma (TFAP2C) can directly bind to the ANXA2 gene, which in turn affects the expression or function of the drug transporter Annexin A2.

TF Superclass2: Zinc-coordinating DNA-binding domains

      Class2.1: Nuclear receptors with C4 zinc fingers

Click to Show/Hide the Full List of 6 TF(s) Regulating This DT

        AR 

Click to Show/Hide to Show 1 Transcriptional Phenomena      

       Transcriptional Phenomenon1

Binding to ANXA2 gene [10]

TF Protein Name

Androgen receptor Transcription Factor Info

Related DT Changes

Direct regulating

Detailed Description

Androgen receptor (AR) has been reported to bind to the transcription of ANXA2 gene in . condition, which leads to a affected expression of the drug transporter Annexin A2.

        ESR1 

Click to Show/Hide to Show 1 Transcriptional Phenomena      

       Transcriptional Phenomenon1

Direct binding to ANXA2 gene [4]

TF Protein Name

Estrogen receptor Transcription Factor Info

Tissue

Breast

Related DT Changes

Direct regulating

Experiment method

TF-transporter regulations were collected from ChIP-Seq datasets.

Detailed Description

Estrogen receptor (ESR1) can directly bind to the ANXA2 gene, which in turn affects the expression or function of the drug transporter Annexin A2.

        HNF4A 

Click to Show/Hide to Show 1 Transcriptional Phenomena      

       Transcriptional Phenomenon1

Binding to ANXA2 gene in health condition [11]

TF Protein Name

Hepatocyte nuclear factor 4-alpha Transcription Factor Info

Studied Phenotype

.

Related DT Changes

Direct regulating

Detailed Description

Hepatocyte nuclear factor 4-alpha (HNF4A) has been reported to bind to the transcription of ANXA2 gene in health condition, which leads to an affected expression of the drug transporter Annexin A2.

        NR2F2 

Click to Show/Hide to Show 1 Transcriptional Phenomena      

       Transcriptional Phenomenon1

Direct binding to ANXA2 gene [2]

TF Protein Name

COUP transcription factor 2 Transcription Factor Info

Tissue

Breast; Liver

Related DT Changes

Direct regulating

Experiment method

TF-transporter regulations were collected from ChIP-Seq datasets.

Detailed Description

COUP transcription factor 2 (NR2F2) can directly bind to the ANXA2 gene, which in turn affects the expression or function of the drug transporter Annexin A2.

        PGR 

Click to Show/Hide to Show 1 Transcriptional Phenomena      

       Transcriptional Phenomenon1

Direct binding to ANXA2 gene [5]

TF Protein Name

Progesterone receptor Transcription Factor Info

Tissue

Breast; Cervix

Related DT Changes

Direct regulating

Experiment method

TF-transporter regulations were collected from ChIP-Seq datasets.

Detailed Description

Progesterone receptor (PGR) can directly bind to the ANXA2 gene, which in turn affects the expression or function of the drug transporter Annexin A2.

        PPARD 

Click to Show/Hide to Show 1 Transcriptional Phenomena      

       Transcriptional Phenomenon1

Repression of ANXA2 gene in myofibroblast condition [12]

TF Protein Name

Peroxisome proliferator-activated receptor delta Transcription Factor Info

Studied Phenotype

.

Related DT Changes

Down regulating

Detailed Description

Peroxisome proliferator-activated receptor delta (PPARD) has been reported to repress the transcription of ANXA2 gene in myofibroblast condition, which leads to a decreased expression of the drug transporter Annexin A2.

      Class2.2: Other C4 zinc finger-type factors

Click to Show/Hide the Full List of 4 TF(s) Regulating This DT

        GATA1 

Click to Show/Hide to Show 1 Transcriptional Phenomena      

       Transcriptional Phenomenon1

Direct binding to ANXA2 gene [5]

TF Protein Name

Erythroid transcription factor Transcription Factor Info

Tissue

Blood; Bone marrow

Related DT Changes

Direct regulating

Experiment method

TF-transporter regulations were collected from ChIP-Seq datasets.

Detailed Description

Erythroid transcription factor (GATA1) can directly bind to the ANXA2 gene, which in turn affects the expression or function of the drug transporter Annexin A2.

        GATA3 

Click to Show/Hide to Show 2 Transcriptional Phenomena      

       Transcriptional Phenomenon1

Binding to ANXA2 gene in breast cancer condition [13]

TF Protein Name

Trans-acting T-cell-specific transcription factor GATA-3 Transcription Factor Info

Studied Phenotype

.

Related DT Changes

Direct regulating

Detailed Description

Trans-acting T-cell-specific transcription factor GATA-3 (GATA3) has been reported to bind to the transcription of ANXA2 gene in breast cancer condition, which leads to an affected expression of the drug transporter Annexin A2.

       Transcriptional Phenomenon2

Direct binding to ANXA2 gene [2]

TF Protein Name

Trans-acting T-cell-specific transcription factor GATA-3 Transcription Factor Info

Tissue

Blood; Brain; Breast; Lung

Related DT Changes

Direct regulating

Experiment method

TF-transporter regulations were collected from ChIP-Seq datasets.

Detailed Description

Trans-acting T-cell-specific transcription factor GATA-3 (GATA3) can directly bind to the ANXA2 gene, which in turn affects the expression or function of the drug transporter Annexin A2.

        GATA4 

Click to Show/Hide to Show 1 Transcriptional Phenomena      

       Transcriptional Phenomenon1

Activation of ANXA2 gene in gastric cancer condition [14]

TF Protein Name

Transcription factor GATA-4 Transcription Factor Info

Studied Phenotype

.

Related DT Changes

Up regulating

Detailed Description

Transcription factor GATA-4 (GATA4) has been reported to activate the transcription of ANXA2 gene in gastric cancer condition, which leads to an increased expression of the drug transporter Annexin A2.

        GATA6 

Click to Show/Hide to Show 1 Transcriptional Phenomena      

       Transcriptional Phenomenon1

Activation of ANXA2 gene in gastric cancer condition [14]

TF Protein Name

Transcription factor GATA-6 Transcription Factor Info

Studied Phenotype

.

Related DT Changes

Up regulating

Detailed Description

Transcription factor GATA-6 (GATA6) has been reported to activate the transcription of ANXA2 gene in gastric cancer condition, which leads to an increased expression of the drug transporter Annexin A2.

      Class2.3: C2H2 zinc finger factors

Click to Show/Hide the Full List of 9 TF(s) Regulating This DT

        KLF1 

Click to Show/Hide to Show 1 Transcriptional Phenomena      

       Transcriptional Phenomenon1

Direct binding to ANXA2 gene [3]

TF Protein Name

Krueppel-like factor 1 Transcription Factor Info

Tissue

Blood

Related DT Changes

Direct regulating

Experiment method

TF-transporter regulations were collected from ChIP-Seq datasets.

Detailed Description

Krueppel-like factor 1 (KLF1) can directly bind to the ANXA2 gene, which in turn affects the expression or function of the drug transporter Annexin A2.

        KLF5 

Click to Show/Hide to Show 1 Transcriptional Phenomena      

       Transcriptional Phenomenon1

Activation of ANXA2 gene in gastric cancer condition [14]

TF Protein Name

Krueppel-like factor 5 Transcription Factor Info

Studied Phenotype

.

Related DT Changes

Up regulating

Detailed Description

Krueppel-like factor 5 (KLF5) has been reported to activate the transcription of ANXA2 gene in gastric cancer condition, which leads to an increased expression of the drug transporter Annexin A2.

        KLF9 

Click to Show/Hide to Show 1 Transcriptional Phenomena      

       Transcriptional Phenomenon1

Direct binding to ANXA2 gene [3]

TF Protein Name

Krueppel-like factor 9 Transcription Factor Info

Related DT Changes

Direct regulating

Experiment method

TF-transporter regulations were collected from ChIP-Seq datasets.

Detailed Description

Krueppel-like factor 9 (KLF9) can directly bind to the ANXA2 gene, which in turn affects the expression or function of the drug transporter Annexin A2.

        MAZ 

Click to Show/Hide to Show 1 Transcriptional Phenomena      

       Transcriptional Phenomenon1

Direct binding to ANXA2 gene [4]

TF Protein Name

Myc-associated zinc finger protein Transcription Factor Info

Tissue

Blood; Bone marrow; Cervix; Lung

Related DT Changes

Direct regulating

Experiment method

TF-transporter regulations were collected from ChIP-Seq datasets.

Detailed Description

Myc-associated zinc finger protein (MAZ) can directly bind to the ANXA2 gene, which in turn affects the expression or function of the drug transporter Annexin A2.

        MECOM 

Click to Show/Hide to Show 1 Transcriptional Phenomena      

       Transcriptional Phenomenon1

Direct binding to ANXA2 gene [5]

TF Protein Name

Histone-lysine N-methyltransferase MECOM Transcription Factor Info

Tissue

Colon

Related DT Changes

Direct regulating

Experiment method

TF-transporter regulations were collected from ChIP-Seq datasets.

Detailed Description

Histone-lysine N-methyltransferase MECOM (MECOM) can directly bind to the ANXA2 gene, which in turn affects the expression or function of the drug transporter Annexin A2.

        VEZF1 

Click to Show/Hide to Show 1 Transcriptional Phenomena      

       Transcriptional Phenomenon1

Direct binding to ANXA2 gene [3]

TF Protein Name

Vascular endothelial zinc finger 1 Transcription Factor Info

Tissue

Colon

Related DT Changes

Direct regulating

Experiment method

TF-transporter regulations were collected from ChIP-Seq datasets.

Detailed Description

Vascular endothelial zinc finger 1 (VEZF1) can directly bind to the ANXA2 gene, which in turn affects the expression or function of the drug transporter Annexin A2.

        ZBTB17 

Click to Show/Hide to Show 1 Transcriptional Phenomena      

       Transcriptional Phenomenon1

Direct binding to ANXA2 gene [2]

TF Protein Name

Zinc finger and BTB domain-containing protein 17 Transcription Factor Info

Tissue

Bone

Related DT Changes

Direct regulating

Experiment method

TF-transporter regulations were collected from ChIP-Seq datasets.

Detailed Description

Zinc finger and BTB domain-containing protein 17 (ZBTB17) can directly bind to the ANXA2 gene, which in turn affects the expression or function of the drug transporter Annexin A2.

        ZNF217 

Click to Show/Hide to Show 1 Transcriptional Phenomena      

       Transcriptional Phenomenon1

Binding to ANXA2 gene in breast cancer condition [15]

TF Protein Name

Zinc finger protein 217 Transcription Factor Info

Studied Phenotype

.

Related DT Changes

Direct regulating

Detailed Description

Zinc finger protein 217 (ZNF217) has been reported to bind to the transcription of ANXA2 gene in breast cancer condition, which leads to an affected expression of the drug transporter Annexin A2.

        ZNF263 

Click to Show/Hide to Show 1 Transcriptional Phenomena      

       Transcriptional Phenomenon1

Direct binding to ANXA2 gene [5]

TF Protein Name

Zinc finger protein 263 Transcription Factor Info

Tissue

Kidney

Related DT Changes

Direct regulating

Experiment method

TF-transporter regulations were collected from ChIP-Seq datasets.

Detailed Description

Zinc finger protein 263 (ZNF263) can directly bind to the ANXA2 gene, which in turn affects the expression or function of the drug transporter Annexin A2.

      Class2.6: CXXC zinc finger factors

Click to Show/Hide the Full List of 1 TF(s) Regulating This DT

        KMT2B 

Click to Show/Hide to Show 1 Transcriptional Phenomena      

       Transcriptional Phenomenon1

Direct binding to ANXA2 gene [4]

TF Protein Name

Histone-lysine N-methyltransferase 2B Transcription Factor Info

Tissue

Colon

Related DT Changes

Direct regulating

Experiment method

TF-transporter regulations were collected from ChIP-Seq datasets.

Detailed Description

Histone-lysine N-methyltransferase 2B (KMT2B) can directly bind to the ANXA2 gene, which in turn affects the expression or function of the drug transporter Annexin A2.

      Class2.8: C3H zinc finger factors

Click to Show/Hide the Full List of 1 TF(s) Regulating This DT

        ZC3H8 

Click to Show/Hide to Show 1 Transcriptional Phenomena      

       Transcriptional Phenomenon1

Direct binding to ANXA2 gene [4]

TF Protein Name

Zinc finger CCCH domain-containing protein 8 Transcription Factor Info

Tissue

Colon

Related DT Changes

Direct regulating

Experiment method

TF-transporter regulations were collected from ChIP-Seq datasets.

Detailed Description

Zinc finger CCCH domain-containing protein 8 (ZC3H8) can directly bind to the ANXA2 gene, which in turn affects the expression or function of the drug transporter Annexin A2.

TF Superclass3: Helix-turn-helix domains

      Class3.1: Homeo domain factors

Click to Show/Hide the Full List of 3 TF(s) Regulating This DT

        HOXB13 

Click to Show/Hide to Show 1 Transcriptional Phenomena      

       Transcriptional Phenomenon1

Direct binding to ANXA2 gene [3]

TF Protein Name

Homeobox protein Hox-B13 Transcription Factor Info

Tissue

Colon; Prostate

Related DT Changes

Direct regulating

Experiment method

TF-transporter regulations were collected from ChIP-Seq datasets.

Detailed Description

Homeobox protein Hox-B13 (HOXB13) can directly bind to the ANXA2 gene, which in turn affects the expression or function of the drug transporter Annexin A2.

        LHX2 

Click to Show/Hide to Show 1 Transcriptional Phenomena      

       Transcriptional Phenomenon1

Direct binding to ANXA2 gene [5]

TF Protein Name

LIM/homeobox protein Lhx2 Transcription Factor Info

Tissue

Epithelium

Related DT Changes

Direct regulating

Experiment method

TF-transporter regulations were collected from ChIP-Seq datasets.

Detailed Description

LIM/homeobox protein Lhx2 (LHX2) can directly bind to the ANXA2 gene, which in turn affects the expression or function of the drug transporter Annexin A2.

        NKX2-1 

Click to Show/Hide to Show 1 Transcriptional Phenomena      

       Transcriptional Phenomenon1

Direct binding to ANXA2 gene [2]

TF Protein Name

Homeobox protein Nkx-2.1 Transcription Factor Info

Tissue

Lung

Related DT Changes

Direct regulating

Experiment method

TF-transporter regulations were collected from ChIP-Seq datasets.

Detailed Description

Homeobox protein Nkx-2.1 (NKX2-1) can directly bind to the ANXA2 gene, which in turn affects the expression or function of the drug transporter Annexin A2.

      Class3.2: Paired box factors

Click to Show/Hide the Full List of 1 TF(s) Regulating This DT

        PAX6 

Click to Show/Hide to Show 1 Transcriptional Phenomena      

       Transcriptional Phenomenon1

Direct binding to ANXA2 gene [2]

TF Protein Name

Paired box protein Pax-6 Transcription Factor Info

Tissue

Epithelium

Related DT Changes

Direct regulating

Experiment method

TF-transporter regulations were collected from ChIP-Seq datasets.

Detailed Description

Paired box protein Pax-6 (PAX6) can directly bind to the ANXA2 gene, which in turn affects the expression or function of the drug transporter Annexin A2.

      Class3.3: Fork head / winged helix factors

Click to Show/Hide the Full List of 7 TF(s) Regulating This DT

        E2F1 

Click to Show/Hide to Show 1 Transcriptional Phenomena      

       Transcriptional Phenomenon1

Direct binding to ANXA2 gene [3]

TF Protein Name

Transcription factor E2F1 Transcription Factor Info

Tissue

Mesenchymal

Related DT Changes

Direct regulating

Experiment method

TF-transporter regulations were collected from ChIP-Seq datasets.

Detailed Description

Transcription factor E2F1 (E2F1) can directly bind to the ANXA2 gene, which in turn affects the expression or function of the drug transporter Annexin A2.

        E2F4 

Click to Show/Hide to Show 1 Transcriptional Phenomena      

       Transcriptional Phenomenon1

Binding to ANXA2 gene in health condition [16]

TF Protein Name

Transcription factor E2F4 Transcription Factor Info

Studied Phenotype

.

Related DT Changes

Direct regulating

Detailed Description

Transcription factor E2F4 (E2F4) has been reported to bind to the transcription of ANXA2 gene in health condition, which leads to an affected expression of the drug transporter Annexin A2.

        E2F6 

Click to Show/Hide to Show 1 Transcriptional Phenomena      

       Transcriptional Phenomenon1

Direct binding to ANXA2 gene [4]

TF Protein Name

Transcription factor E2F6 Transcription Factor Info

Tissue

Bone marrow; Embryo; Lung

Related DT Changes

Direct regulating

Experiment method

TF-transporter regulations were collected from ChIP-Seq datasets.

Detailed Description

Transcription factor E2F6 (E2F6) can directly bind to the ANXA2 gene, which in turn affects the expression or function of the drug transporter Annexin A2.

        FOXA1 

Click to Show/Hide to Show 1 Transcriptional Phenomena      

       Transcriptional Phenomenon1

Direct binding to ANXA2 gene [2]

TF Protein Name

Hepatocyte nuclear factor 3-alpha Transcription Factor Info

Tissue

Breast; Embryo; Liver; Lung; Pancreatic ductal; Prostate

Related DT Changes

Direct regulating

Experiment method

TF-transporter regulations were collected from ChIP-Seq datasets.

Detailed Description

Hepatocyte nuclear factor 3-alpha (FOXA1) can directly bind to the ANXA2 gene, which in turn affects the expression or function of the drug transporter Annexin A2.

        FOXA2 

Click to Show/Hide to Show 2 Transcriptional Phenomena      

       Transcriptional Phenomenon1

Binding to ANXA2 gene in health condition [11]

TF Protein Name

Hepatocyte nuclear factor 3-beta Transcription Factor Info

Studied Phenotype

.

Related DT Changes

Direct regulating

Detailed Description

Hepatocyte nuclear factor 3-beta (FOXA2) has been reported to bind to the transcription of ANXA2 gene in health condition, which leads to an affected expression of the drug transporter Annexin A2.

       Transcriptional Phenomenon2

Direct binding to ANXA2 gene [3]

TF Protein Name

Hepatocyte nuclear factor 3-beta Transcription Factor Info

Tissue

Colon

Related DT Changes

Direct regulating

Experiment method

TF-transporter regulations were collected from ChIP-Seq datasets.

Detailed Description

Hepatocyte nuclear factor 3-beta (FOXA2) can directly bind to the ANXA2 gene, which in turn affects the expression or function of the drug transporter Annexin A2.

        FOXM1 

Click to Show/Hide to Show 1 Transcriptional Phenomena      

       Transcriptional Phenomenon1

Activation of ANXA2 gene in breast cancer condition [17]

TF Protein Name

Forkhead box protein M1 Transcription Factor Info

Studied Phenotype

.

Related DT Changes

Up regulating

Detailed Description

Forkhead box protein M1 (FOXM1) has been reported to activate the transcription of ANXA2 gene in breast cancer condition, which leads to an increased expression of the drug transporter Annexin A2.

        FOXO3 

Click to Show/Hide to Show 1 Transcriptional Phenomena      

       Transcriptional Phenomenon1

Direct binding to ANXA2 gene [4]

TF Protein Name

Forkhead box protein O3 Transcription Factor Info

Tissue

Bone marrow; Colon

Related DT Changes

Direct regulating

Experiment method

TF-transporter regulations were collected from ChIP-Seq datasets.

Detailed Description

Forkhead box protein O3 (FOXO3) can directly bind to the ANXA2 gene, which in turn affects the expression or function of the drug transporter Annexin A2.

      Class3.5: Tryptophan cluster factors

Click to Show/Hide the Full List of 7 TF(s) Regulating This DT

        ELK1 

Click to Show/Hide to Show 1 Transcriptional Phenomena      

       Transcriptional Phenomenon1

Binding to ANXA2 gene in . condition [18]

TF Protein Name

ETS domain-containing protein Elk-1 Transcription Factor Info

Related DT Changes

Direct regulating

Detailed Description

ETS domain-containing protein Elk-1 (ELK1) has been reported to bind to the transcription of ANXA2 gene in . condition, which leads to an affected expression of the drug transporter Annexin A2.

        ERG 

Click to Show/Hide to Show 1 Transcriptional Phenomena      

       Transcriptional Phenomenon1

Repression of ANXA2 gene in prostate cancer condition [19]

TF Protein Name

Transcriptional regulator ERG Transcription Factor Info

Studied Phenotype

Prostate cancer [ICD11: 2C82]

Tissue

Prostate

Related DT Changes

Down regulating

Experimental Material

Human prostate carcinoma cells (VCaP)

Detailed Description

Transcriptional regulator ERG (ERG) has been reported to repress the transcription of ANXA2 gene in prostate cancer condition, which leads to a decreased expression of the drug transporter Annexin A2.

        ETS1 

Click to Show/Hide to Show 1 Transcriptional Phenomena      

       Transcriptional Phenomenon1

Direct binding to ANXA2 gene [5]

TF Protein Name

Protein C-ets-1 Transcription Factor Info

Tissue

Blood; Bone; Bone marrow; Kidney; Lung; Prostate; Vein

Related DT Changes

Direct regulating

Experiment method

TF-transporter regulations were collected from ChIP-Seq datasets.

Detailed Description

Protein C-ets-1 (ETS1) can directly bind to the ANXA2 gene, which in turn affects the expression or function of the drug transporter Annexin A2.

        ETV7 

Click to Show/Hide to Show 1 Transcriptional Phenomena      

       Transcriptional Phenomenon1

Direct binding to ANXA2 gene [5]

TF Protein Name

Transcription factor ETV7 Transcription Factor Info

Tissue

Colon

Related DT Changes

Direct regulating

Experiment method

TF-transporter regulations were collected from ChIP-Seq datasets.

Detailed Description

Transcription factor ETV7 (ETV7) can directly bind to the ANXA2 gene, which in turn affects the expression or function of the drug transporter Annexin A2.

        FLI1 

Click to Show/Hide to Show 1 Transcriptional Phenomena      

       Transcriptional Phenomenon1

Direct binding to ANXA2 gene [2]

TF Protein Name

Friend leukemia integration 1 transcription factor Transcription Factor Info

Tissue

Blood; Mesenchymal; Vein

Related DT Changes

Direct regulating

Experiment method

TF-transporter regulations were collected from ChIP-Seq datasets.

Detailed Description

Friend leukemia integration 1 transcription factor (FLI1) can directly bind to the ANXA2 gene, which in turn affects the expression or function of the drug transporter Annexin A2.

        MYB 

Click to Show/Hide to Show 1 Transcriptional Phenomena      

       Transcriptional Phenomenon1

Direct binding to ANXA2 gene [5]

TF Protein Name

Transcriptional activator Myb Transcription Factor Info

Tissue

Blood

Related DT Changes

Direct regulating

Experiment method

TF-transporter regulations were collected from ChIP-Seq datasets.

Detailed Description

Transcriptional activator Myb (MYB) can directly bind to the ANXA2 gene, which in turn affects the expression or function of the drug transporter Annexin A2.

        SPI1 

Click to Show/Hide to Show 1 Transcriptional Phenomena      

       Transcriptional Phenomenon1

Direct binding to ANXA2 gene [3]

TF Protein Name

Transcription factor PU.1 Transcription Factor Info

Tissue

Adrenal gland; Blood; Bone marrow; Brain; Breast; Embryo; Foreskin; Heart; Intestine; Kidney; Lung; Muscle; Penis; Placenta; Renal cortex; Renal pelvis; Skin; Spinal cord; Stomach; Testes; Umbilical cord blood

Related DT Changes

Direct regulating

Experiment method

TF-transporter regulations were collected from ChIP-Seq datasets.

Detailed Description

Transcription factor PU.1 (SPI1) can directly bind to the ANXA2 gene, which in turn affects the expression or function of the drug transporter Annexin A2.

      Class3.6: TEA domain factors

Click to Show/Hide the Full List of 1 TF(s) Regulating This DT

        TEAD4 

Click to Show/Hide to Show 1 Transcriptional Phenomena      

       Transcriptional Phenomenon1

Direct binding to ANXA2 gene [3]

TF Protein Name

Transcriptional enhancer factor TEF-3 Transcription Factor Info

Tissue

Bone marrow; Brain; Breast; Colon; Embryo; Liver; Lung; Uterus

Related DT Changes

Direct regulating

Experiment method

TF-transporter regulations were collected from ChIP-Seq datasets.

Detailed Description

Transcriptional enhancer factor TEF-3 (TEAD4) can directly bind to the ANXA2 gene, which in turn affects the expression or function of the drug transporter Annexin A2.

      Class3.7: ARID domain factors

Click to Show/Hide the Full List of 2 TF(s) Regulating This DT

        ARID3A 

Click to Show/Hide to Show 1 Transcriptional Phenomena      

       Transcriptional Phenomenon1

Direct binding to ANXA2 gene [4]

TF Protein Name

AT-rich interactive domain-containing protein 3A Transcription Factor Info

Tissue

Liver

Related DT Changes

Direct regulating

Experiment method

TF-transporter regulations were collected from ChIP-Seq datasets.

Detailed Description

AT-rich interactive domain-containing protein 3A (ARID3A) can directly bind to the ANXA2 gene, which in turn affects the expression or function of the drug transporter Annexin A2.

        KDM5B 

Click to Show/Hide to Show 1 Transcriptional Phenomena      

       Transcriptional Phenomenon1

Direct binding to ANXA2 gene [4]

TF Protein Name

Lysine-specific demethylase 5B Transcription Factor Info

Tissue

Bone marrow; Breast

Related DT Changes

Direct regulating

Experiment method

TF-transporter regulations were collected from ChIP-Seq datasets.

Detailed Description

Lysine-specific demethylase 5B (KDM5B) can directly bind to the ANXA2 gene, which in turn affects the expression or function of the drug transporter Annexin A2.

TF Superclass6: Immunoglobulin fold

      Class6.2: STAT domain factors

Click to Show/Hide the Full List of 1 TF(s) Regulating This DT

        STAT3 

Click to Show/Hide to Show 1 Transcriptional Phenomena      

       Transcriptional Phenomenon1

Activation of ANXA2 gene in non-alcoholic steatohepatitis condition [20]

TF Protein Name

Signal transducer and activator of transcription 3 Transcription Factor Info

Studied Phenotype

Non-alcoholic steatohepatitis [ICD11: DB92.1]

Tissue

Liver

Related DT Changes

Up regulating

Experimental Material

C57BL/6J mice

Detailed Description

Signal transducer and activator of transcription 3 (STAT3) has been reported to activate the transcription of ANXA2 gene in non-alcoholic steatohepatitis condition, which leads to an increased expression of the drug transporter Annexin A2.

      Class6.3: p53 domain factors

Click to Show/Hide the Full List of 2 TF(s) Regulating This DT

        TP53 

Click to Show/Hide to Show 1 Transcriptional Phenomena      

       Transcriptional Phenomenon1

Binding to ANXA2 gene in tumor condition [21]

TF Protein Name

Cellular tumor antigen p53 Transcription Factor Info

Studied Phenotype

.

Related DT Changes

Direct regulating

Detailed Description

Cellular tumor antigen p53 (TP53) has been reported to bind to the transcription of ANXA2 gene in tumor condition, which leads to an affected expression of the drug transporter Annexin A2.

        TP63 

Click to Show/Hide to Show 2 Transcriptional Phenomena      

       Transcriptional Phenomenon1

Binding to ANXA2 gene in epithelial to mesenchymal transition condition [22]

TF Protein Name

Tumor protein 63 Transcription Factor Info

Studied Phenotype

.

Related DT Changes

Direct regulating

Detailed Description

Tumor protein 63 (TP63) has been reported to bind to the transcription of ANXA2 gene in epithelial to mesenchymal transition condition, which leads to an affected expression of the drug transporter Annexin A2.

       Transcriptional Phenomenon2

Binding to ANXA2 gene in health condition [23]

TF Protein Name

Tumor protein 63 Transcription Factor Info

Studied Phenotype

.

Related DT Changes

Direct regulating

Detailed Description

Tumor protein 63 (TP63) has been reported to bind to the transcription of ANXA2 gene in health condition, which leads to an affected expression of the drug transporter Annexin A2.

      Class6.4: Runt domain factors

Click to Show/Hide the Full List of 2 TF(s) Regulating This DT

        RUNX2 

Click to Show/Hide to Show 1 Transcriptional Phenomena      

       Transcriptional Phenomenon1

Activation of ANXA2 gene in prostate cancer condition [24]

TF Protein Name

Runt-related transcription factor 2 Transcription Factor Info

Studied Phenotype

.

Related DT Changes

Up regulating

Detailed Description

Runt-related transcription factor 2 (RUNX2) has been reported to activate the transcription of ANXA2 gene in prostate cancer condition, which leads to an increased expression of the drug transporter Annexin A2.

        RUNX3 

Click to Show/Hide to Show 1 Transcriptional Phenomena      

       Transcriptional Phenomenon1

Direct binding to ANXA2 gene [5]

TF Protein Name

Runt-related transcription factor 3 Transcription Factor Info

Tissue

Blood

Related DT Changes

Direct regulating

Experiment method

TF-transporter regulations were collected from ChIP-Seq datasets.

Detailed Description

Runt-related transcription factor 3 (RUNX3) can directly bind to the ANXA2 gene, which in turn affects the expression or function of the drug transporter Annexin A2.

      Class6.7: Grainyhead domain factors

Click to Show/Hide the Full List of 1 TF(s) Regulating This DT

        GRHL2 

Click to Show/Hide to Show 1 Transcriptional Phenomena      

       Transcriptional Phenomenon1

Direct binding to ANXA2 gene [4]

TF Protein Name

Grainyhead-like protein 2 homolog Transcription Factor Info

Tissue

Breast; Bronchus; Ovary; Prostate

Related DT Changes

Direct regulating

Experiment method

TF-transporter regulations were collected from ChIP-Seq datasets.

Detailed Description

Grainyhead-like protein 2 homolog (GRHL2) can directly bind to the ANXA2 gene, which in turn affects the expression or function of the drug transporter Annexin A2.

TF Superclass7: beta-Hairpin exposed by an alpha/beta-scaffold

      Class7.1: SMAD/NF-1 DNA-binding domain factors

Click to Show/Hide the Full List of 3 TF(s) Regulating This DT

        NFIC 

Click to Show/Hide to Show 1 Transcriptional Phenomena      

       Transcriptional Phenomenon1

Direct binding to ANXA2 gene [2]

TF Protein Name

Nuclear factor 1 C-type Transcription Factor Info

Tissue

Brain; Liver; Uterus

Related DT Changes

Direct regulating

Experiment method

TF-transporter regulations were collected from ChIP-Seq datasets.

Detailed Description

Nuclear factor 1 C-type (NFIC) can directly bind to the ANXA2 gene, which in turn affects the expression or function of the drug transporter Annexin A2.

        SMAD3 

Click to Show/Hide to Show 1 Transcriptional Phenomena      

       Transcriptional Phenomenon1

Binding to ANXA2 gene in HaCaT keratinocytes condition [25]

TF Protein Name

Mothers against decapentaplegic homolog 3 Transcription Factor Info

Related DT Changes

Direct regulating

Detailed Description

Mothers against decapentaplegic homolog 3 (SMAD3) has been reported to bind to the transcription of ANXA2 gene in HaCaT keratinocytes condition, which leads to an affected expression of the drug transporter Annexin A2.

        SMAD4 

Click to Show/Hide to Show 1 Transcriptional Phenomena      

       Transcriptional Phenomenon1

Binding to ANXA2 gene in health condition [26]

TF Protein Name

Mothers against decapentaplegic homolog 4 Transcription Factor Info

Studied Phenotype

.

Related DT Changes

Direct regulating

Detailed Description

Mothers against decapentaplegic homolog 4 (SMAD4) has been reported to bind to the transcription of ANXA2 gene in health condition, which leads to an affected expression of the drug transporter Annexin A2.

TF Superclass8: beta-Sheet binding to DNA

      Class8.1: TATA-binding proteins

Click to Show/Hide the Full List of 1 TF(s) Regulating This DT

        TBP 

Click to Show/Hide to Show 1 Transcriptional Phenomena      

       Transcriptional Phenomenon1

Direct binding to ANXA2 gene [2]

TF Protein Name

TATA-box-binding protein Transcription Factor Info

Tissue

Blood; Bone marrow; Cervix; Embryo

Related DT Changes

Direct regulating

Experiment method

TF-transporter regulations were collected from ChIP-Seq datasets.

Detailed Description

TATA-box-binding protein (TBP) can directly bind to the ANXA2 gene, which in turn affects the expression or function of the drug transporter Annexin A2.

TF Superclass10: Yet undefined DNA-binding domains

      Class10.1: Other factors

Click to Show/Hide the Full List of 2 TF(s) Regulating This DT

        REPIN1 

Click to Show/Hide to Show 1 Transcriptional Phenomena      

       Transcriptional Phenomenon1

Direct binding to ANXA2 gene [2]

TF Protein Name

Replication initiator 1 Transcription Factor Info

Tissue

Colon

Related DT Changes

Direct regulating

Experiment method

TF-transporter regulations were collected from ChIP-Seq datasets.

Detailed Description

Replication initiator 1 (REPIN1) can directly bind to the ANXA2 gene, which in turn affects the expression or function of the drug transporter Annexin A2.

        ZZZ3 

Click to Show/Hide to Show 1 Transcriptional Phenomena      

       Transcriptional Phenomenon1

Direct binding to ANXA2 gene [3]

TF Protein Name

ZZ-type zinc finger-containing protein 3 Transcription Factor Info

Tissue

Blood; Cervix

Related DT Changes

Direct regulating

Experiment method

TF-transporter regulations were collected from ChIP-Seq datasets.

Detailed Description

ZZ-type zinc finger-containing protein 3 (ZZZ3) can directly bind to the ANXA2 gene, which in turn affects the expression or function of the drug transporter Annexin A2.
References
1 In vivo RNAi screen for BMI1 targets identifies TGF-BMP-ER stress pathways as key regulators of neural- and malignant glioma-stem cell homeostasis. Cancer Cell. 2013;23(5):660-76.
2 hTFtarget: A Comprehensive Database for Regulations of Human Transcription Factors and Their Targets. Genomics Proteomics Bioinformatics. 2020 Apr;18(2):120-422. (ID:ENSG00000182718)
3 NCBI GEO: archive for functional genomics data sets--update. Nucleic Acids Res. 2013 Jan;41(D1):D991-5.
4 Closure of the NCBI SRA and implications for the long-term future of genomics data storage. Genome Biol. 2011;12(3):402.
5 The Encyclopedia of DNA elements (ENCODE): data portal update. Nucleic Acids Res. 2018 Jan 4;46(D1):D794-D801
6 Characterization of TCF21 Downstream Target Regions Identifies a Transcriptional Network Linking Multiple Independent Coronary Artery Disease Loci. PLoS Genet. 2015;11(5):e1005202.
7 Mutations in the circadian gene CLOCK in colorectal cancer. Mol Cancer Res. 2010;8(7):952-60.
8 Essential role of microphthalmia transcription factor for DNA replication, mitosis and genomic stability in melanoma. Oncogene. 2011;30(20):2319-32.
9 Unique genome-wide map of TCF4 and STAT3 targets using ChIP-seq reveals their association with new molecular subtypes of glioblastoma. Neuro Oncol. 2013;15(3):279-89.
10 Genome-wide analysis of ETS-family DNA-binding in vitro and in vivo. EMBO J. 2010;29(13):2147-60.
11 Molecular interactions between HNF4a, FOXA2 and GABP identified at regulatory DNA elements through ChIP-sequencing. Nucleic Acids Res. 2009;37(22):7498-508.
12 Genomewide analyses define different modes of transcriptional regulation by peroxisome proliferator-activated receptor. PLoS One. 2011;6(1):e16344.
13 Breast tumor specific mutation in GATA3 affects physiological mechanisms regulating transcription factor turnover. BMC Cancer. 2014;14:278.
14 Regulatory crosstalk between lineage-survival oncogenes KLF5, GATA4 and GATA6 cooperatively promotes gastric cancer development. Gut. 2015;64(5):707-19.
15 Global analysis of ZNF217 chromatin occupancy in the breast cancer cell genome reveals an association with ERalpha. BMC Genomics. 2014;15(1):520.
16 Wide-ranging functions of E2F4 in transcriptional activation and repression revealed by genome-wide analysis. Nucleic Acids Res. 2011;39(9):3558-73.
17 FOXM1 cistrome predicts breast cancer metastatic outcome better than FOXM1 expression levels or tumor proliferation index. Breast Cancer Res Treat. 2015;154(1):23-32.
18 ELK1 uses different DNA binding modes to regulate functionally distinct classes of target genes. PLoS Genet. 2012;8(5):e1002694.
19 ERG oncoprotein inhibits ANXA2 expression and function in prostate cancer. Mol Cancer Res. 2015 Feb;13(2):368-79.
20 The p-STAT3/ANXA2 axis promotes caspase-1-mediated hepatocyte pyroptosis in non-alcoholic steatohepatitis. J Transl Med. 2022 Nov 2;20(1):497.
21 Characterization of genome-wide p53-binding sites upon stress response. Nucleic Acids Res. 2008;36(11):3639-54.
22 p63 attenuates epithelial to mesenchymal potential in an experimental prostate cell model. PLoS One. 2013;8(5):e62547.
23 Genome-wide analysis of p63 binding sites identifies AP-2 factors as co-regulators of epidermal differentiation. Nucleic Acids Res. 2012;40(15):7190-206.
24 Genome-wide Runx2 occupancy in prostate cancer cells suggests a role in regulating secretion. Nucleic Acids Res. 2012;40(8):3538-47.
25 Chromatin immunoprecipitation on microarray analysis of Smad2/3 binding sites reveals roles of ETS1 and TFAP2A in transforming growth factor beta signaling. Mol Cell Biol. 2009;29(1):172-86.
26 Promoter-wide analysis of Smad4 binding sites in human epithelial cells. Cancer Sci. 2009;100(11):2133-42.

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