Microbe Species Information

General Information of This Microbe species
Species ID
MIC00039
Species Name
Lactobacillus acidophilus
Taxonomy ID
1579
Lineage
Kingdom:Bacteria
Phylum:Bacillota
Class:Bacilli
Order:Lactobacillales
Family:Lactobacillaceae
Genus: Lactobacillus
Species: Lactobacillus acidophilus
Drug Transporter(s) Regulated by This Microbe species

Class4: Microbiota regulating the expression and function of DT via other mechanisms

DAT1

 Transporter Info

Fatal diarrhea/infections with enteropathogenic Escherichia coli [ICD11: 1A03]

 [1], [2], [3]

MRP2

 Transporter Info

Diabetes [ICD11: 5A10-5A14]

 [4], [5]

SLC26A3

 Transporter Info

Diarrhea [ICD11: ME05.1]

 [6], [7]

SLC9A3

 Transporter Info

Fatal diarrhea/infections with enteropathogenic Escherichia coli [ICD11: 1A03]

 [1], [2], [3]
Species Relative Abundances of This Microbe species
References
1 Decreased expression of colonic Slc26a3 and carbonic anhydrase iv as a cause of fatal infectious diarrhea in mice. Infect Immun. 2009 Sep;77(9):3639-50.
2 The Role of Ion Transporters in the Pathophysiology of Infectious Diarrhea. Cell Mol Gastroenterol Hepatol. 2018 Mar 5;6(1):33-45.
3 Infectious diarrhea: Cellular and molecular mechanisms. Gut Microbes. 2010 Jan;1(1):4-21.
4 The influence of the gut microbiota on the bioavailability of oral drugs. Acta Pharm Sin B. 2021 Jul;11(7):1789-1812.
5 Probiotic Pre-treatment Reduces Gliclazide Permeation (ex vivo) in Healthy Rats but Increases It in Diabetic Rats to the Level Seen in Untreated Healthy Rats. Arch Drug Inf. 2008 Jul;1(1):35-41.
6 Mechanisms of the intestinal and urinary microbiome in kidney stone disease. Nat Rev Urol. 2022 Dec;19(12):695-707.
7 Lactobacillus acidophilus stimulates the expression of SLC26A3 via a transcriptional mechanism. Am J Physiol Gastrointest Liver Physiol. 2010 Mar;298(3):G395-401.

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