Modelled Stucture
Method:Homology modeling
Teplate PDB:5GJV_A
Identity:69.088%
Minimized Score:-2785.464
Detail: Structure Info
Detail Information of Inter-species Structural Difference
| General Information of Drug Transporter (DT) | |||||
|---|---|---|---|---|---|
| DT ID | DTD0534 Transporter Info | ||||
| Gene Name | CACNA1C | ||||
| Protein Name | Voltage-gated calcium channel alpha Cav1.2 | ||||
| Gene ID | |||||
| UniProt ID | |||||
| 3D Structure |
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| Inter-species Structural Differences (ISD) | |||||
| Gallus gallus (Chicken) | |||||
| Gene Name | CACNA1C | ||||
| UniProt ID | |||||
| UniProt Entry | |||||
| 3D Structure |
Method:Homology modeling Teplate PDB:6JPA_A Sequence Length:176 Identity:68.718% |
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| Click to Save PDB File in TXT Format | |||||
| Performance | Minimized Score | -357.131 kcal/mol | |||
| Ramachandra Favored | Medium |
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| QMEANBrane Quality | Medium |
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| Ramachandran Plot |
Ramz Z Score:-2.23 ±0.6 Residues in Favored Region:167 Ramachandran favored:95.98% Number of Outliers:1 Ramachandran outliers:0.57% |
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| Click to Save Ramachandran Plot in PNG Format | |||||
| Local Quality |
QMEANBrane Score:0.76 |
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| Click to Save Local Quality Plot in PNG Format | |||||
| Cavia porcellus (Guinea pig) | |||||
| Gene Name | CACNA1C | ||||
| UniProt ID | |||||
| UniProt Entry | |||||
| 3D Structure |
Method:Homology modeling Teplate PDB:5GJV_A Sequence Length:1667 Identity:69.382% |
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| Click to Save PDB File in TXT Format | |||||
| Performance | Minimized Score | -2795.077 kcal/mol | |||
| Ramachandra Favored | Poor |
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| QMEANBrane Quality | Medium |
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| Ramachandran Plot |
Ramz Z Score:-1.91 ±0.19 Residues in Favored Region:1567 Ramachandran favored:94.11% Number of Outliers:22 Ramachandran outliers:1.32% |
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| Click to Save Ramachandran Plot in PNG Format | |||||
| Local Quality |
QMEANBrane Score:0.76 |
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| Click to Save Local Quality Plot in PNG Format | |||||
| References | |||||
| 1 | Structural basis of the alpha1-beta subunit interaction of voltage-gated Ca2+ channels. Nature. 2004 Jun 10;429(6992):675-80. | ||||
| 2 | The role of a voltage-dependent Ca2+ channel intracellular linker: a structure-function analysis. J Neurosci. 2012 May 30;32(22):7602-13. | ||||
| 3 | RCSB PDB: apo-Calmodulin Bound to Calcium Voltage Gated Channel 1.2 IQ-Motif. | ||||
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