General Information of Drug Transporter (DT)
DT ID DTD0518 Transporter Info
Gene Name CACNA1A
Protein Name Voltage-gated calcium channel alpha Cav2.1
Gene ID
773
UniProt ID
O00555
3D Structure

Modelled Stucture

Method:Homology modeling

Teplate PDB:6JPA_A

Identity:49.337%

Minimized Score:-1477.492

Detail: Structure Info

Inter-species Structural Differences (ISD)
Gallus gallus (Chicken)
        Gene Name CACNA1A
        UniProt ID
O73705
        UniProt Entry
CAC1A_CHICK
        3D Structure

Method:Homology modeling

Teplate PDB:6JPA_A

Sequence Length:171

Identity:49.746%

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        Performance Minimized Score -385.048 kcal/mol
Ramachandra Favored

Medium

QMEANBrane Quality

Medium

        Ramachandran Plot

Ramz Z Score:-1.88 ±0.6

Residues in Favored Region:161

Ramachandran favored:95.27%

Number of Outliers:1

Ramachandran outliers:0.59%

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        Local Quality

QMEANBrane Score:0.76

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References
1 Structures of CaV2 Ca2+/CaM-IQ domain complexes reveal binding modes that underlie calcium-dependent inactivation and facilitation. Structure. 2008 Oct 8;16(10):1455-67.

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