Modelled Stucture
Method:Homology modeling
Teplate PDB:6JPA_A
Identity:49.337%
Minimized Score:-1477.492
Detail: Structure Info
Detail Information of Inter-species Structural Difference
| General Information of Drug Transporter (DT) | |||||
|---|---|---|---|---|---|
| DT ID | DTD0518 Transporter Info | ||||
| Gene Name | CACNA1A | ||||
| Protein Name | Voltage-gated calcium channel alpha Cav2.1 | ||||
| Gene ID | |||||
| UniProt ID | |||||
| 3D Structure |
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| Inter-species Structural Differences (ISD) | |||||
| Mus musculus (Mouse) | |||||
| Gene Name | Cacna1a | ||||
| UniProt ID | |||||
| UniProt Entry | |||||
| 3D Structure |
Method:Homology modeling Teplate PDB:5GJV_A Sequence Length:818 Identity:45.539% |
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| Click to Save PDB File in TXT Format | |||||
| Performance | Minimized Score | -1404.569 kcal/mol | |||
| Ramachandra Favored | Poor |
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| QMEANBrane Quality | Medium |
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| Ramachandran Plot |
Ramz Z Score:-2.31 ±0.26 Residues in Favored Region:762 Ramachandran favored:93.38% Number of Outliers:16 Ramachandran outliers:1.96% |
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| Click to Save Ramachandran Plot in PNG Format | |||||
| Local Quality |
QMEANBrane Score:0.76 |
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| Click to Save Local Quality Plot in PNG Format | |||||
| Rattus norvegicus (Rat) | |||||
| Gene Name | Cacna1a | ||||
| UniProt ID | |||||
| UniProt Entry | |||||
| 3D Structure |
Method:Homology modeling Teplate PDB:5GJV_A Sequence Length:818 Identity:45.771% |
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| Click to Save PDB File in TXT Format | |||||
| Performance | Minimized Score | -1419.97 kcal/mol | |||
| Ramachandra Favored | Poor |
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| QMEANBrane Quality | Medium |
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| Ramachandran Plot |
Ramz Z Score:-1.62 ±0.28 Residues in Favored Region:762 Ramachandran favored:93.38% Number of Outliers:11 Ramachandran outliers:1.35% |
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| Click to Save Ramachandran Plot in PNG Format | |||||
| Local Quality |
QMEANBrane Score:0.76 |
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| Click to Save Local Quality Plot in PNG Format | |||||
| Oryctolagus cuniculus (Rabbit) | |||||
| Gene Name | CACNA1A | ||||
| UniProt ID | |||||
| UniProt Entry | |||||
| 3D Structure |
Method:Homology modeling Teplate PDB:5GJV_A Sequence Length:798 Identity:45.53% |
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| Click to Save PDB File in TXT Format | |||||
| Performance | Minimized Score | -1547.65 kcal/mol | |||
| Ramachandra Favored | Poor |
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| QMEANBrane Quality | Medium |
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| Ramachandran Plot |
Ramz Z Score:-1.63 ±0.27 Residues in Favored Region:753 Ramachandran favored:94.60% Number of Outliers:9 Ramachandran outliers:1.13% |
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| Click to Save Ramachandran Plot in PNG Format | |||||
| Local Quality |
QMEANBrane Score:0.76 |
||||
| Click to Save Local Quality Plot in PNG Format | |||||
| Experimental Structures of This Model Oganism | |||||
| PDB ID | Scanning Method | Resolution | Expression System | Details | Ref |
| 3DVM | X-ray | 2.6 Å | Escherichia coli | [ 1] | |
| Structure | |||||
| Click to Save PDB File in TXT Format | |||||
| Corresponding chain | B | ||||
| Sequence Length | 1963-1982 | Mutation | No | ||
| References | |||||
| 1 | Structures of CaV2 Ca2+/CaM-IQ domain complexes reveal binding modes that underlie calcium-dependent inactivation and facilitation. Structure. 2008 Oct 8;16(10):1455-67. | ||||
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