General Information of Drug Transporter (DT)
DT ID DTD0336 Transporter Info
Gene Name SLC38A9
Protein Name Sodium-coupled neutral amino acid transporter 9
Gene ID
153129
UniProt ID
Q8NBW4
3D Structure

Modelled Stucture

Method:Homology modeling

Teplate PDB:6C08_C

Identity:66.32%

Minimized Score:-385.896

Detail: Structure Info

Inter-species Structural Differences (ISD)
Xenopus laevis (African clawed frog)
        Gene Name slc38a9
        UniProt ID
Q6DFK0
        UniProt Entry
S38A9_XENLA
        3D Structure

Method:Homology modeling

Teplate PDB:7KGV_A

Sequence Length:554

Identity:65.468%

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        Performance Minimized Score -1142.798 kcal/mol
Ramachandra Favored

Medium

QMEANBrane Quality

Medium

        Ramachandran Plot

Ramz Z Score:-1.21 ±0.33

Residues in Favored Region:527

Ramachandran favored:95.47%

Number of Outliers:5

Ramachandran outliers:0.91%

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        Local Quality

QMEANBrane Score:0.74

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Xenopus tropicalis (Western clawed frog)
        Gene Name slc38a9
        UniProt ID
Q5M7S0
        UniProt Entry
S38A9_XENTR
        3D Structure

Method:Homology modeling

Teplate PDB:7KGV_A

Sequence Length:554

Identity:65.225%

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        Performance Minimized Score -1139.551 kcal/mol
Ramachandra Favored

Medium

QMEANBrane Quality

Medium

        Ramachandran Plot

Ramz Z Score:-1.2 ±0.33

Residues in Favored Region:527

Ramachandran favored:95.47%

Number of Outliers:4

Ramachandran outliers:0.72%

Click to Save Ramachandran Plot in PNG Format
        Local Quality

QMEANBrane Score:0.74

Click to Save Local Quality Plot in PNG Format
References
1 A conformational change in the N terminus of SLC38A9 signals mTORC1 activation. Structure. 2021;29(5):426-432.e8.

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