General Information of Drug Transporter (DT)
DT ID DTD0336 Transporter Info
Gene Name SLC38A9
Protein Name Sodium-coupled neutral amino acid transporter 9
Gene ID
153129
UniProt ID
Q8NBW4
3D Structure

Modelled Stucture

Method:Homology modeling

Teplate PDB:6C08_C

Identity:66.32%

Minimized Score:-385.896

Detail: Structure Info

Inter-species Structural Differences (ISD)
Mus musculus (Mouse)
        Gene Name Slc38a9
        UniProt ID
Q8BGD6
        UniProt Entry
S38A9_MOUSE
        3D Structure

Method:Homology modeling

Teplate PDB:7KGV_A

Sequence Length:557

Identity:62.903%

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        Performance Minimized Score -1094.167 kcal/mol
Ramachandra Favored

Medium

QMEANBrane Quality

Medium

        Ramachandran Plot

Ramz Z Score:-1.39 ±0.34

Residues in Favored Region:528

Ramachandran favored:95.14%

Number of Outliers:7

Ramachandran outliers:1.26%

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        Local Quality

QMEANBrane Score:0.74

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Rattus norvegicus (Rat)
        Gene Name Slc38a9
        UniProt ID
Q3B8Q3
        UniProt Entry
S38A9_RAT
        3D Structure

Method:Homology modeling

Teplate PDB:7KGV_A

Sequence Length:556

Identity:62.724%

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        Performance Minimized Score -1105.451 kcal/mol
Ramachandra Favored

Medium

QMEANBrane Quality

Medium

        Ramachandran Plot

Ramz Z Score:-1.18 ±0.34

Residues in Favored Region:531

Ramachandran favored:95.85%

Number of Outliers:5

Ramachandran outliers:0.90%

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        Local Quality

QMEANBrane Score:0.74

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Danio rerio (Zebrafish)
        Gene Name slc38a9
        UniProt ID
Q08BA4
        UniProt Entry
S38A9_DANRE
        3D Structure

Method:Homology modeling

Teplate PDB:7KGV_A

Sequence Length:549

Identity:99.271%

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        Performance Minimized Score -1135.247 kcal/mol
Ramachandra Favored

Poor

QMEANBrane Quality

Medium

        Ramachandran Plot

Ramz Z Score:-1.4 ±0.34

Residues in Favored Region:519

Ramachandran favored:94.88%

Number of Outliers:5

Ramachandran outliers:0.91%

Click to Save Ramachandran Plot in PNG Format
        Local Quality

QMEANBrane Score:0.74

Click to Save Local Quality Plot in PNG Format
References
1 A conformational change in the N terminus of SLC38A9 signals mTORC1 activation. Structure. 2021;29(5):426-432.e8.

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