Drug Information

General Information
Drug ID
DR00289
Drug Name
Vitamin C
Synonyms
(2R)-2-[(1S)-1,2-Dihydroxyethyl]-4,5-dihydroxy-furan-3-one; (2R)-2-[(1S)-1,2-dihydroxyethyl]-4,5-dihydroxyfuran-3-one; (5R)-5-[(1S)-1,2-dihydroxyethyl]-3,4-dihydroxyfuran-2(5H)-one; 2-(1,2-Dihydroxyethyl)-4,5-dihydroxyfuran-3-one; 3-Keto-L-gulofuranolactone; 3-Oxo-L-gulofuranolactone; 3-Oxo-L-gulofuranolactone (enol form); Acid Ascorbic; Acide ascorbique; Acide ascorbique [INN-French]; Acido ascorbico; Acido ascorbico [INN-Spanish]; Acidum ascorbicum; Acidum ascorbicum [INN-Latin]; Acidum ascorbinicum; Adenex; Allercorb; Antiscorbic vita min; Antiscorbic vitamin; Antiscorbutic factor; Antiscorbutic vitamin; Arco-cee; Ascoltin; Ascoltin (TN); Ascor-B.I.D.; Ascor-b.i.d; Ascorb; Ascorbajen; Ascorbate; Ascorbic Acid, Monosodium Salt; Ascorbic acid; Ascorbic acid (JP15/USP/INN); Ascorbic acid [BAN:INN:JAN]; Ascorbic acid [INN:BAN:JAN]; Ascorbicab; Ascorbicap; Ascorbicap (TN); Ascorbicin; Ascorbinsaeure; Ascorbutina; Ascorbyl radical; Ascorin; Ascorteal; Ascorvit; C-Level; C-Long; C-Quin; C-Span; C-Vimin; CE-VI-Sol; Cantan; Cantaxin; Catavin C; Ce lent; Ce-Mi-Lin; Cebicure; Cebid; Cebion; Cebione; Cecon; Cee-Vite; Cee-caps td; Cegiolan; Ceglion; Celaskon; Celin; Cemagyl; Cemill; Cenetone; Cenolate; Cereon; Cergona; Cescorbat; Cetamid; Cetane-Caps TC; Cetane-Caps TD; Cetebe; Cetemican; Cevalin; Cevatine; Cevex; Cevi-Bid; Cevibid; Cevimin; Cevital; Cevitamic acid; Cevitamin; Cevitan; Cevitex; Cewin; Ciamin; Cipca; Citriscorb; Colascor; Component of Cortalex; Component of E and C-Level; Component of Endoglobin Forte; Component of Ferancee; Concemin; Cortalex; Davitamon C; Dora-C-500; Duoscorb; Ferancee; Ferrous ascorbate; Hicee; Hybrin; IDO-C; Iron(II) ascorbate; Iron-ascorbic acid complexes;L-Ascorbic acid; Kyselina askorbova; Kyselina askorbova [Czech]; L(+)-Ascorbic acid; L-(+)-Ascorbic Acid; L-3-Ketothreohexuronic acid lactone; L-3-ketothreohexuronic acid; L-Ascorbic acid, free radical form; L-Lyxoascorbic acid; L-Threoascorbic acid; L-Xyloascorbic acid; L-ascorbate; L-ascorbic acid; L-threo-Hex-2-enonic acid, gamma-lactone; L-threo-ascorbic acid; L-threo-hex-1-eofuranos-3-ulose; L-threo-hex-2-enono-1,4-lactone; Laroscorbine; Lemascorb; Liqui-Cee; Magnesium Ascorbicum; Magnorbin; Meri-C; Monodehydroascorbic acid; Natrascorb; Natrascorb injectable; Oral Vitamin C; Planavit C; Proscorbin; Redoxon; Ribena; Roscorbi c; Roscorbic; Scorbacid; Scorbu-C; Secorbate; Semidehydroascorbate; Sodascorbate; Sodium Ascorbate (Ascorbic Acid); Stuartinic; Sunkist; Testascorbic; Tolfrinic; Vicelat; Vicin; Vicomin C; Viforcit; Viscorin; Vitace; Vitacee; Vitacimin; Vitacin; Vitamin-C; Vitamisin; Vitascorbol; Xitix
Drug Type
Small molecular drug
Indication Vitamin C deficiency [ICD11:5B56] Approved [1]
Therapeutic Class
Vitamins
Structure
3D MOL 2D MOL
Formula
C6H8O6
Canonical SMILES
C(C(C1C(=C(C(=O)O1)O)O)O)O
InChI
InChI=1S/C6H8O6/c7-1-2(8)5-3(9)4(10)6(11)12-5/h2,5,7-10H,1H2/t2-,5+/m0/s1
InChIKey
CIWBSHSKHKDKBQ-JLAZNSOCSA-N
CAS Number
CAS 50-81-7
Pharmaceutical Properties Molecular Weight 176.12 Topological Polar Surface Area 107
Heavy Atom Count 12 Rotatable Bond Count 2
Hydrogen Bond Donor Count 4 Hydrogen Bond Acceptor Count 6
XLogP
-1.6
PubChem CID
54670067
PubChem SID
11528251 ,14717141 ,15219590 ,15321981 ,17390038 ,22395201 ,24855464 ,24859847 ,24871532 ,24890105 ,24890106 ,24890107 ,24890417 ,24890632 ,24890635 ,24890649 ,24890857 ,24890875 ,24891042 ,24891246 ,24891432 ,24900863 ,26757776 ,29203862 ,29224819 ,3132038 ,3372 ,36507993 ,46505070 ,47662544 ,47960008 ,48259498 ,48413235 ,48415580 ,48416719 ,48423587 ,48425237 ,49684275 ,49699000 ,49737747 ,50105612 ,53790060 ,56310862 ,56313946 ,56314017 ,597821 ,7847086 ,7885976 ,8145471 ,828416
ChEBI ID
ChEBI:29073
TTD Drug ID
D07AHW
DT(s) Transporting This Drug SVCT1 Transporter Info Sodium-dependent vitamin C transporter 1 Substrate [2]
SVCT2 Transporter Info Sodium-dependent vitamin C transporter 2 Substrate [3]
References
1 Vitamin C was approved by FDA. The official website of the U.S. Food and Drug Administration. (2019)
2 A family of mammalian Na+-dependent L-ascorbic acid transporters. Nature. 1999 May 6;399(6731):70-5.
3 Molecular characterization and transcriptional regulation of the sodium-dependent vitamin C transporter genes (slc23a1 and slc23a2) in a teleost fish, the Senegalese sole (Solea senegalensis). Comp Biochem Physiol B Biochem Mol Biol. 2012 Mar;161(3):208-18.

If you find any error in data or bug in web service, please kindly report it to Dr. Li and Dr. Fu.