Detail Information of Exogenous Modulation

General Information of Drug Transporter (DT)
DT ID	DTD0251 Transporter Info
Gene Name	SLC2A1
Transporter Name	Glucose transporter type 1, erythrocyte/brain
Gene ID	6513
UniProt ID	P11166

Exogenous factors (drugs, dietary constituents, etc.) Modulation of This DT (EGM)
Mycotoxins
Aflatoxin B1	1 DT Activity Modulations Related to This Exogenous Factor		Click to Show/Hide the Full List
DT Modulation1	Aflatoxin B1 results in increased methylation of SLC2A1 intron			[102]
Regulation Mechanism				Transcription Factor Info
ochratoxin A	2 DT Activity Modulations Related to This Exogenous Factor		Click to Show/Hide the Full List
DT Modulation1	ochratoxin A results in increased expression of SLC2A1 mRNA			[71]
Regulation Mechanism				Transcription Factor Info
DT Modulation2	ochratoxin A results in increased expression of SLC2A1 protein			[71]
Regulation Mechanism				Transcription Factor Info
Nanoparticle
perfluoro-n-nonanoic acid	1 DT Activity Modulations Related to This Exogenous Factor		Click to Show/Hide the Full List
DT Modulation1	perfluoro-n-nonanoic acid results in increased expression of SLC2A1 mRNA			[150]
Regulation Mechanism				Transcription Factor Info
Approved Drug
Caffeine	3 DT Activity Modulations Related to This Exogenous Factor		Click to Show/Hide the Full List
DT Modulation1	Caffeine inhibits the transportation of 3-O-methylglucose by SLC2A1 (Ki = 3500 microM)			[1]
Affected Drug/Substrate	3-O-methylglucose	Modulation Type	Inhibition
Cell System	Human erythrocytes-GLUT1
Dapagliflozin	1 DT Activity Modulations Related to This Exogenous Factor		Click to Show/Hide the Full List
DT Modulation1	Dapagliflozin inhibits the transportation of 2-Deoxyglucose by SLC2A1			[2]
Affected Drug/Substrate	2-Deoxyglucose	Modulation Type	Inhibition
Rosiglitazone	2 DT Activity Modulations Related to This Exogenous Factor		Click to Show/Hide the Full List
DT Modulation1	Rosiglitazone increases the expression of SLC2A1			[4]
Regulation Mechanism	via enhancement of the transcriptional activation of Peroxisome proliferator-activated receptor gamma (PPARG)			Transcription Factor Info
Cell System	Mouse differentiated adipocytes (3T3-L1)
Cupric chloride	1 DT Activity Modulations Related to This Exogenous Factor		Click to Show/Hide the Full List
DT Modulation1	Cupric chloride increases the expression of SLC2A1			[5]
Regulation Mechanism	via enhancement of Hypoxia-inducible factor 1-alpha (HIF1A)			Transcription Factor Info
Cell System	Human childhood hepatocellular carcinoma cells (Hep3B)
Ibuprofen	2 DT Activity Modulations Related to This Exogenous Factor		Click to Show/Hide the Full List
DT Modulation1	Ibuprofen inhibits the expression of SLC2A1			[6]
Regulation Mechanism	via the inhibition of Hypoxia-inducible factor 1-alpha (HIF1A)			Transcription Factor Info
Cell System	Human prostate carcinoma cells (DU145)
DT Modulation2	Ibuprofen results in increased expression of SLC2A1 mRNA			[25]
Regulation Mechanism				Transcription Factor Info
Pentobarbital	4 DT Activity Modulations Related to This Exogenous Factor		Click to Show/Hide the Full List
DT Modulation1	Pentobarbital inhibits the activity of SLC2A1			[7]
Phenobarbital	5 DT Activity Modulations Related to This Exogenous Factor		Click to Show/Hide the Full List
DT Modulation1	Phenobarbital inhibits the activity of SLC2A1			[7]
Troglitazone	3 DT Activity Modulations Related to This Exogenous Factor		Click to Show/Hide the Full List
DT Modulation1	Troglitazone inhibits the expression of SLC2A1			[8]
Estradiol	2 DT Activity Modulations Related to This Exogenous Factor		Click to Show/Hide the Full List
DT Modulation1	Estradiol increases the expression of SLC2A1			[9]
Diethylstilbestrol	3 DT Activity Modulations Related to This Exogenous Factor		Click to Show/Hide the Full List
DT Modulation1	Diethylstilbestrol inhibits the activity of SLC2A1			[10]
Tamoxifen	3 DT Activity Modulations Related to This Exogenous Factor		Click to Show/Hide the Full List
DT Modulation1	Tamoxifen inhibits the activity of SLC2A1			[10]
Progesterone	3 DT Activity Modulations Related to This Exogenous Factor		Click to Show/Hide the Full List
DT Modulation1	Progesterone increases the expression of SLC2A1			[11]
Liothyronine	1 DT Activity Modulations Related to This Exogenous Factor		Click to Show/Hide the Full List
DT Modulation1	Liothyronine increases the expression of SLC2A1			[12]
Fluorouracil	3 DT Activity Modulations Related to This Exogenous Factor		Click to Show/Hide the Full List
DT Modulation1	Fluorouracil inhibits the expression of SLC2A1			[13]
Ciprofloxacin	2 DT Activity Modulations Related to This Exogenous Factor		Click to Show/Hide the Full List
DT Modulation1	Ciprofloxacin inhibits the expression of SLC2A1			[14]
Ofloxacin	2 DT Activity Modulations Related to This Exogenous Factor		Click to Show/Hide the Full List
DT Modulation1	Ofloxacin inhibits the expression of SLC2A1			[14]
Celecoxib	1 DT Activity Modulations Related to This Exogenous Factor		Click to Show/Hide the Full List
DT Modulation1	Celecoxib increases the expression of SLC2A1			[15]
Copper Sulfate	1 DT Activity Modulations Related to This Exogenous Factor		Click to Show/Hide the Full List
DT Modulation1	Copper Sulfate affects the expression of SLC2A1			[16]
Menadione	1 DT Activity Modulations Related to This Exogenous Factor		Click to Show/Hide the Full List
DT Modulation1	Menadione affects the expression of SLC2A1			[17]
Hydrogen Peroxide	2 DT Activity Modulations Related to This Exogenous Factor		Click to Show/Hide the Full List
DT Modulation1	Hydrogen Peroxide inhibits the expression of SLC2A1			[18]
Cytarabine	1 DT Activity Modulations Related to This Exogenous Factor		Click to Show/Hide the Full List
DT Modulation1	Cytarabine inhibits the expression of SLC2A1			[19]
Niclosamide	1 DT Activity Modulations Related to This Exogenous Factor		Click to Show/Hide the Full List
DT Modulation1	Niclosamide inhibits the expression of SLC2A1			[20]
Doxorubicin	2 DT Activity Modulations Related to This Exogenous Factor		Click to Show/Hide the Full List
DT Modulation1	Doxorubicin inhibits the expression of SLC2A1			[21]
Tretinoin	1 DT Activity Modulations Related to This Exogenous Factor		Click to Show/Hide the Full List
DT Modulation1	Tretinoin inhibits the expression of SLC2A1			[22]
Zidovudine	1 DT Activity Modulations Related to This Exogenous Factor		Click to Show/Hide the Full List
DT Modulation1	Zidovudine inhibits the expression of SLC2A1			[23]
Cyclosporine	2 DT Activity Modulations Related to This Exogenous Factor		Click to Show/Hide the Full List
DT Modulation1	Cyclosporine inhibits the expression of SLC2A1			[24]
Cidofovir	1 DT Activity Modulations Related to This Exogenous Factor		Click to Show/Hide the Full List
DT Modulation1	Cidofovir increases the expression of SLC2A1			[25]
Ifosfamide	1 DT Activity Modulations Related to This Exogenous Factor		Click to Show/Hide the Full List
DT Modulation1	Ifosfamide increases the expression of SLC2A1			[25]
Vorinostat	1 DT Activity Modulations Related to This Exogenous Factor		Click to Show/Hide the Full List
DT Modulation1	Vorinostat inhibits the expression of SLC2A1			[26]
Leflunomide	1 DT Activity Modulations Related to This Exogenous Factor		Click to Show/Hide the Full List
DT Modulation1	Leflunomide increases the expression of SLC2A1			[27]
Cisplatin	5 DT Activity Modulations Related to This Exogenous Factor		Click to Show/Hide the Full List
DT Modulation1	Cisplatin inhibits the expression of SLC2A1			[28]
Glycine	1 DT Activity Modulations Related to This Exogenous Factor		Click to Show/Hide the Full List
DT Modulation1	Glycine inhibits the expression of SLC2A1			[29]
Sunitinib	1 DT Activity Modulations Related to This Exogenous Factor		Click to Show/Hide the Full List
DT Modulation1	Sunitinib increases the expression of SLC2A1			[30]
Temozolomide	1 DT Activity Modulations Related to This Exogenous Factor		Click to Show/Hide the Full List
DT Modulation1	Temozolomide increases the expression of SLC2A1			[31]
Dronabinol	1 DT Activity Modulations Related to This Exogenous Factor		Click to Show/Hide the Full List
DT Modulation1	Dronabinol inhibits the expression of SLC2A1			[32]
Ivermectin	1 DT Activity Modulations Related to This Exogenous Factor		Click to Show/Hide the Full List
DT Modulation1	Ivermectin inhibits the expression of SLC2A1			[33]
Imatinib Mesylate	1 DT Activity Modulations Related to This Exogenous Factor		Click to Show/Hide the Full List
DT Modulation1	Imatinib Mesylate inhibits the expression of SLC2A1			[34]
Benzatropine	1 DT Activity Modulations Related to This Exogenous Factor		Click to Show/Hide the Full List
DT Modulation1	Benzatropine inhibits the expression of SLC2A1			[35]
Cannabidiol	1 DT Activity Modulations Related to This Exogenous Factor		Click to Show/Hide the Full List
DT Modulation1	Cannabidiol inhibits the expression of SLC2A1			[35]
Propofol	1 DT Activity Modulations Related to This Exogenous Factor		Click to Show/Hide the Full List
DT Modulation1	Propofol inhibits the expression of SLC2A1			[36]
Sevoflurane	1 DT Activity Modulations Related to This Exogenous Factor		Click to Show/Hide the Full List
DT Modulation1	Sevoflurane increases the expression of SLC2A1			[36]
Amiodarone	1 DT Activity Modulations Related to This Exogenous Factor		Click to Show/Hide the Full List
DT Modulation1	Amiodarone inhibits the expression of SLC2A1			[37]
Arsenic Trioxide	12 DT Activity Modulations Related to This Exogenous Factor		Click to Show/Hide the Full List
DT Modulation1	Arsenic Trioxide increases the expression of SLC2A1			[38]
Valproic Acid	5 DT Activity Modulations Related to This Exogenous Factor		Click to Show/Hide the Full List
DT Modulation1	Valproic Acid inhibits the expression of SLC2A1			[26]
Pioglitazone	1 DT Activity Modulations Related to This Exogenous Factor		Click to Show/Hide the Full List
DT Modulation1	Pioglitazone induces the activity of SLC2A1			[39]
Tolazamide	1 DT Activity Modulations Related to This Exogenous Factor		Click to Show/Hide the Full List
DT Modulation1	Tolazamide induces the activity of SLC2A1			[40]
Dihydroergotamine	1 DT Activity Modulations Related to This Exogenous Factor		Click to Show/Hide the Full List
DT Modulation1	Dihydroergotamine induces the activity of SLC2A1			[41]
Ergotamine	1 DT Activity Modulations Related to This Exogenous Factor		Click to Show/Hide the Full List
DT Modulation1	Ergotamine induces the activity of SLC2A1			[41]
Drug Marketed but not Approved by US FDA
Daidzein	1 DT Activity Modulations Related to This Exogenous Factor		Click to Show/Hide the Full List
DT Modulation1	Daidzein inhibits the activity of SLC2A1			[10]
Rotenone	4 DT Activity Modulations Related to This Exogenous Factor		Click to Show/Hide the Full List
DT Modulation1	Rotenone inhibits the expression of SLC2A1			[37]
Drug in Phase 3 Trial
Triclosan	1 DT Activity Modulations Related to This Exogenous Factor		Click to Show/Hide the Full List
DT Modulation1	Triclosan increases the expression of SLC2A1			[66]
Drug in Phase 2 Trial
Genistein	3 DT Activity Modulations Related to This Exogenous Factor		Click to Show/Hide the Full List
DT Modulation1	Genistein inhibits the activity of SLC2A1			[10]
Bisphenol A	1 DT Activity Modulations Related to This Exogenous Factor		Click to Show/Hide the Full List
DT Modulation1	Bisphenol A increases the expression of SLC2A1			[78]
Drug in Phase 1 Trial
Dihydrotestosterone	1 DT Activity Modulations Related to This Exogenous Factor		Click to Show/Hide the Full List
DT Modulation1	Dihydrotestosterone increases the expression of SLC2A1			[45]
Regulation Mechanism	via enhancement of Hypoxia-inducible factor 1-alpha (HIF1A)			Transcription Factor Info
Cell System	Human prostate carcinoma cells (LNCaP)
Naringenin	1 DT Activity Modulations Related to This Exogenous Factor		Click to Show/Hide the Full List
DT Modulation1	Naringenin inhibits the activity of SLC2A1			[10]
Quercetin	5 DT Activity Modulations Related to This Exogenous Factor		Click to Show/Hide the Full List
DT Modulation1	Quercetin inhibits the expression of SLC2A1			[51]
Trichostatin A	1 DT Activity Modulations Related to This Exogenous Factor		Click to Show/Hide the Full List
DT Modulation1	Trichostatin A increases the expression of SLC2A1			[58]
LY-294002	1 DT Activity Modulations Related to This Exogenous Factor		Click to Show/Hide the Full List
DT Modulation1	LY-294002 inhibits the expression of SLC2A1			[76]
Sodium arsenite	1 DT Activity Modulations Related to This Exogenous Factor		Click to Show/Hide the Full List
DT Modulation1	Sodium arsenite inhibits the expression of SLC2A1			[37]
Drug in Preclinical Test
Isoliquiritigenin	1 DT Activity Modulations Related to This Exogenous Factor		Click to Show/Hide the Full List
DT Modulation1	Isoliquiritigenin inhibits the activity of SLC2A1			[10]
Myricetin	1 DT Activity Modulations Related to This Exogenous Factor		Click to Show/Hide the Full List
DT Modulation1	Myricetin inhibits the activity of SLC2A1			[10]
MRK-003	1 DT Activity Modulations Related to This Exogenous Factor		Click to Show/Hide the Full List
DT Modulation1	MRK-003 inhibits the expression of SLC2A1			[50]
Investigative Drug
MG-132	1 DT Activity Modulations Related to This Exogenous Factor		Click to Show/Hide the Full List
DT Modulation1	MG-132 increases the expression of SLC2A1			[43]
Regulation Mechanism	via enhancement of Hypoxia-inducible factor 1-alpha (HIF1A)			Transcription Factor Info
Cell System	Human gestational choriocarcinoma cells (BeWo)
Glucose	26 DT Activity Modulations Related to This Exogenous Factor		Click to Show/Hide the Full List
DT Modulation1	Glucose increases the expression of SLC2A1			[49]
Protoporphyrin IX	1 DT Activity Modulations Related to This Exogenous Factor		Click to Show/Hide the Full List
DT Modulation1	Protoporphyrin IX inhibits the expression of SLC2A1			[56]
Phenylmercuric Acetate	2 DT Activity Modulations Related to This Exogenous Factor		Click to Show/Hide the Full List
DT Modulation1	Phenylmercuric Acetate increases the expression of SLC2A1			[61]
PP242	1 DT Activity Modulations Related to This Exogenous Factor		Click to Show/Hide the Full List
DT Modulation1	PP242 inhibits the expression of SLC2A1			[67]
Beta-naphthoflavone	1 DT Activity Modulations Related to This Exogenous Factor		Click to Show/Hide the Full List
DT Modulation1	Beta-naphthoflavone inhibits the expression of SLC2A1			[72]
Natural Product
DT Modulation1	Caffeine results in decreased phosphorylation of SLC2A1 protein			[127]
Regulation Mechanism				Transcription Factor Info
DT Modulation2	Caffeine results in increased expression of SLC2A1 protein			[128]
Regulation Mechanism				Transcription Factor Info
Alpha-naphthoflavone	1 DT Activity Modulations Related to This Exogenous Factor		Click to Show/Hide the Full List
DT Modulation1	Alpha-naphthoflavone increases the expression of SLC2A1			[42]
Regulation Mechanism	via modulation of Aryl hydrocarbon receptor (AHR)			Transcription Factor Info
Cell System	Mouse teratocarcinoma cells (P19)
7-hydroxyflavone	3 DT Activity Modulations Related to This Exogenous Factor		Click to Show/Hide the Full List
DT Modulation1	7-hydroxyflavone inhibits the activity of SLC2A1			[10]
Phloretin	3 DT Activity Modulations Related to This Exogenous Factor		Click to Show/Hide the Full List
DT Modulation1	Phloretin inhibits the activity of SLC2A1			[10]
Dust	1 DT Activity Modulations Related to This Exogenous Factor		Click to Show/Hide the Full List
DT Modulation1	Dust increases the expression of SLC2A1			[48]
DT Modulation1	Quercetin affects the localization of SLC2A1 protein			[179]
Regulation Mechanism				Transcription Factor Info
DT Modulation2	Quercetin inhibits the reaction SLC2A1 protein affects the transport of Glucose			[10]
Regulation Mechanism				Transcription Factor Info
DT Modulation3	Quercetin inhibits the reaction SLC2A1 protein results in increased uptake of 2-(N-(7-nitrobenz-2-oxa-1,3-diazol-4-yl)amino)-2-deoxyglucose			[87]
Regulation Mechanism				Transcription Factor Info
DT Modulation4	Quercetin results in decreased activity of SLC2A1 protein			[10]
Regulation Mechanism				Transcription Factor Info
Particulate Matter	1 DT Activity Modulations Related to This Exogenous Factor		Click to Show/Hide the Full List
DT Modulation1	Particulate Matter inhibits the expression of SLC2A1			[73]
Deguelin	1 DT Activity Modulations Related to This Exogenous Factor		Click to Show/Hide the Full List
DT Modulation1	Deguelin increases the expression of SLC2A1			[74]
Tobacco Smoke Pollution	1 DT Activity Modulations Related to This Exogenous Factor		Click to Show/Hide the Full List
DT Modulation1	Tobacco Smoke Pollution increases the expression of SLC2A1			[75]
Curcumin	3 DT Activity Modulations Related to This Exogenous Factor		Click to Show/Hide the Full List
DT Modulation1	ATF4 inhibits the reaction Curcumin results in decreased expression of SLC2A1 protein			[96]
Regulation Mechanism				Transcription Factor Info
DT Modulation2	Curcumin inhibits the reaction 4,6-dimorpholino-N-(4-nitrophenyl)-1,3,5-triazin-2-amine results in increased phosphorylation of SLC2A1 protein			[96]
Regulation Mechanism				Transcription Factor Info
DT Modulation3	Curcumin results in decreased expression of SLC2A1 protein			[96]
Regulation Mechanism				Transcription Factor Info
Resveratrol	3 DT Activity Modulations Related to This Exogenous Factor		Click to Show/Hide the Full List
DT Modulation1	Resveratrol binds to SLC2A1 protein			[161]
Regulation Mechanism				Transcription Factor Info
DT Modulation2	Resveratrol binds to SLC2A1 protein which results in decreased transport of Hexoses			[161]
Regulation Mechanism				Transcription Factor Info
DT Modulation3	Resveratrol inhibits the reaction SLC2A1 protein results in increased uptake of Glucose			[161]
Regulation Mechanism				Transcription Factor Info
Traditional Medicine
Jinfukang	1 DT Activity Modulations Related to This Exogenous Factor		Click to Show/Hide the Full List
DT Modulation1	Jinfukang increases the expression of SLC2A1			[62]
Dietary Constituent
Red wine	1 DT Activity Modulations Related to This Exogenous Factor		Click to Show/Hide the Full List
DT Modulation1	Red wine inhibits the activity of SLC2A1			[3]
Cell System	Human erythrocytes-GLUT1
Biotoxin
Dinophysistoxin 1	1 DT Activity Modulations Related to This Exogenous Factor		Click to Show/Hide the Full List
DT Modulation1	Dinophysistoxin 1 increases the expression of SLC2A1			[65]
dinophysistoxin 1	1 DT Activity Modulations Related to This Exogenous Factor		Click to Show/Hide the Full List
DT Modulation1	dinophysistoxin 1 results in increased expression of SLC2A1 mRNA			[65]
Regulation Mechanism				Transcription Factor Info
yessotoxin	1 DT Activity Modulations Related to This Exogenous Factor		Click to Show/Hide the Full List
DT Modulation1	yessotoxin analog results in increased expression of SLC2A1 mRNA			[67]
Regulation Mechanism				Transcription Factor Info
Environmental toxicant
Polychlorinated dibenzodioxin	1 DT Activity Modulations Related to This Exogenous Factor		Click to Show/Hide the Full List
DT Modulation1	Polychlorinated dibenzodioxin inhibits the expression of SLC2A1			[55]
Glyphosate	1 DT Activity Modulations Related to This Exogenous Factor		Click to Show/Hide the Full List
DT Modulation1	Glyphosate increases the expression of SLC2A1			[29]
Lead	4 DT Activity Modulations Related to This Exogenous Factor		Click to Show/Hide the Full List
DT Modulation1	lead acetate results in increased abundance of Lead which results in decreased expression of SLC2A1 mRNA			[165]
Regulation Mechanism				Transcription Factor Info
DT Modulation2	lead acetate results in increased abundance of Lead which results in decreased expression of SLC2A1 protein			[165]
Regulation Mechanism				Transcription Factor Info
DT Modulation3	PPIF protein affects the reaction lead acetate results in increased abundance of Lead which results in decreased expression of SLC2A1 mRNA			[165]
Regulation Mechanism				Transcription Factor Info
DT Modulation4	PPIF protein affects the reaction lead acetate results in increased abundance of Lead which results in decreased expression of SLC2A1 protein			[165]
Regulation Mechanism				Transcription Factor Info
Acute Toxic Substance
Nickel chloride	1 DT Activity Modulations Related to This Exogenous Factor		Click to Show/Hide the Full List
DT Modulation1	Nickel chloride increases the expression of SLC2A1			[46]
Regulation Mechanism	via enhancement of Hypoxia-inducible factor 1-alpha (HIF1A)			Transcription Factor Info
Cell System	BALB/c mice
Cadmium	6 DT Activity Modulations Related to This Exogenous Factor		Click to Show/Hide the Full List
DT Modulation1	Cadmium increases the expression of SLC2A1			[54]
Kaempferol	1 DT Activity Modulations Related to This Exogenous Factor		Click to Show/Hide the Full List
DT Modulation1	Kaempferol inhibits the expression of SLC2A1			[59]
Thimerosal	1 DT Activity Modulations Related to This Exogenous Factor		Click to Show/Hide the Full List
DT Modulation1	Thimerosal inhibits the expression of SLC2A1			[26]
Chloropicrin	1 DT Activity Modulations Related to This Exogenous Factor		Click to Show/Hide the Full List
DT Modulation1	Chloropicrin inhibits the expression of SLC2A1			[64]
Okadaic Acid	1 DT Activity Modulations Related to This Exogenous Factor		Click to Show/Hide the Full List
DT Modulation1	Okadaic Acid increases the expression of SLC2A1			[65]
Ochratoxin A	1 DT Activity Modulations Related to This Exogenous Factor		Click to Show/Hide the Full List
DT Modulation1	Ochratoxin A increases the expression of SLC2A1			[71]
Formaldehyde	5 DT Activity Modulations Related to This Exogenous Factor		Click to Show/Hide the Full List
DT Modulation1	Formaldehyde increases the expression of SLC2A1			[77]
Carcinogen
Sodium bichromate	1 DT Activity Modulations Related to This Exogenous Factor		Click to Show/Hide the Full List
DT Modulation1	Sodium bichromate inhibits the expression of SLC2A1			[47]
Benzo(a)pyrene	5 DT Activity Modulations Related to This Exogenous Factor		Click to Show/Hide the Full List
DT Modulation1	Benzo(a)pyrene inhibits the expression of SLC2A1			[52]
DT Modulation1	3-methyladenine inhibits the reaction Cadmium Chloride results in increased abundance of Cadmium which results in increased expression of SLC2A1 protein			[89]
Regulation Mechanism				Transcription Factor Info
DT Modulation2	Cadmium Chloride results in increased abundance of Cadmium which results in increased expression of SLC2A1 protein			[89]
Regulation Mechanism				Transcription Factor Info
DT Modulation3	Carbonyl Cyanide m-Chlorophenyl Hydrazone inhibits the reaction Cadmium Chloride results in increased abundance of Cadmium which results in increased expression of SLC2A1 protein			[89]
Regulation Mechanism				Transcription Factor Info
DT Modulation4	HMGA2 protein affects the reaction Cadmium Chloride results in increased abundance of Cadmium which results in increased expression of SLC2A1 protein			[89]
Regulation Mechanism				Transcription Factor Info
DT Modulation5	Sirolimus inhibits the reaction Cadmium Chloride results in increased abundance of Cadmium which results in increased expression of SLC2A1 protein			[92]
Regulation Mechanism				Transcription Factor Info
Ethyl Methanesulfonate	1 DT Activity Modulations Related to This Exogenous Factor		Click to Show/Hide the Full List
DT Modulation1	Ethyl Methanesulfonate inhibits the expression of SLC2A1			[57]
DT Modulation1	Deferoxamine inhibits the reaction myricetin inhibits the reaction Formaldehyde results in increased expression of SLC2A1 mRNA			[77]
Regulation Mechanism				Transcription Factor Info
DT Modulation2	Deferoxamine inhibits the reaction myricetin inhibits the reaction Formaldehyde results in increased expression of SLC2A1 protein			[77]
Regulation Mechanism				Transcription Factor Info
DT Modulation3	myricetin inhibits the reaction Formaldehyde results in increased expression of SLC2A1 mRNA			[77]
Regulation Mechanism				Transcription Factor Info
DT Modulation4	myricetin inhibits the reaction Formaldehyde results in increased expression of SLC2A1 protein			[77]
Regulation Mechanism				Transcription Factor Info
Arsenic	1 DT Activity Modulations Related to This Exogenous Factor		Click to Show/Hide the Full List
DT Modulation1	sodium arsenite results in increased abundance of Arsenic inhibits the reaction Deoxyglucose results in increased abundance of Glucose which affects the localization of SLC2A1 protein			[108]
Regulation Mechanism				Transcription Factor Info
Nickel	1 DT Activity Modulations Related to This Exogenous Factor		Click to Show/Hide the Full List
DT Modulation1	Nickel results in increased expression of SLC2A1 mRNA			[171]
Regulation Mechanism				Transcription Factor Info
Fungicide
Prochloraz	1 DT Activity Modulations Related to This Exogenous Factor		Click to Show/Hide the Full List
DT Modulation1	Prochloraz inhibits the expression of SLC2A1			[68]
Pesticide/Insecticide
Dicrotophos	1 DT Activity Modulations Related to This Exogenous Factor		Click to Show/Hide the Full List
DT Modulation1	Dicrotophos increases the expression of SLC2A1			[63]
DDT	4 DT Activity Modulations Related to This Exogenous Factor		Click to Show/Hide the Full List
DT Modulation1	2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction DDT results in increased expression of SLC2A1 mRNA			[83]
Regulation Mechanism				Transcription Factor Info
DT Modulation2	Acetylcysteine inhibits the reaction DDT results in increased expression of SLC2A1 mRNA			[83]
Regulation Mechanism				Transcription Factor Info
DT Modulation3	DDT results in increased expression of SLC2A1 mRNA			[83]
Regulation Mechanism				Transcription Factor Info
DT Modulation4	PKM protein alternative form affects the reaction DDT results in increased expression of SLC2A1 mRNA			[83]
Regulation Mechanism				Transcription Factor Info
Health and Environmental Toxicant
tris(1,3-dichloro-2-propyl)phosphate	2 DT Activity Modulations Related to This Exogenous Factor		Click to Show/Hide the Full List
DT Modulation1	tris(1,3-dichloro-2-propyl)phosphate inhibits the expression of SLC2A1			[60]
Azaspiracid	1 DT Activity Modulations Related to This Exogenous Factor		Click to Show/Hide the Full List
DT Modulation1	Azaspiracid increases the expression of SLC2A1			[65]
Diethylhexyl Phthalate	2 DT Activity Modulations Related to This Exogenous Factor		Click to Show/Hide the Full List
DT Modulation1	Diethylhexyl Phthalate inhibits the expression of SLC2A1			[69]
Perfluorooctane sulfonic acid	1 DT Activity Modulations Related to This Exogenous Factor		Click to Show/Hide the Full List
DT Modulation1	Perfluorooctane sulfonic acid inhibits the expression of SLC2A1			[70]
Herbicide
Atrazine	1 DT Activity Modulations Related to This Exogenous Factor		Click to Show/Hide the Full List
DT Modulation1	Atrazine inhibits the expression of SLC2A1			[53]
Chemical Compound
DT Modulation1	Rosiglitazone results in increased expression of SLC2A1 mRNA			[25]
Regulation Mechanism				Transcription Factor Info
DT Modulation1	Pentobarbital inhibits the reaction SLC2A1 protein results in increased uptake of 3-O-Methylglucose			[7]
Regulation Mechanism				Transcription Factor Info
DT Modulation2	Pentobarbital promotes the reaction SLC2A1 gene polymorphism results in decreased uptake of 3-O-Methylglucose			[7]
Regulation Mechanism				Transcription Factor Info
DT Modulation3	Pentobarbital results in decreased activity of SLC2A1 protein			[7]
Regulation Mechanism				Transcription Factor Info
DT Modulation1	Phenobarbital affects the expression of SLC2A1 mRNA			[178]
Regulation Mechanism				Transcription Factor Info
DT Modulation2	Phenobarbital inhibits the reaction SLC2A1 protein results in increased uptake of 3-O-Methylglucose			[7]
Regulation Mechanism				Transcription Factor Info
DT Modulation3	Phenobarbital promotes the reaction SLC2A1 gene polymorphism results in decreased uptake of 3-O-Methylglucose			[7]
Regulation Mechanism				Transcription Factor Info
DT Modulation4	Phenobarbital results in decreased activity of SLC2A1 protein			[7]
Regulation Mechanism				Transcription Factor Info
DT Modulation1	Troglitazone results in increased expression of SLC2A1 mRNA			[187]
Regulation Mechanism				Transcription Factor Info
DT Modulation2	Troglitazone results in increased expression of SLC2A1 protein			[188]
Regulation Mechanism				Transcription Factor Info
DT Modulation1	Progesterone co-treated with Estradiol results in decreased expression of SLC2A1 protein			[11]
Regulation Mechanism				Transcription Factor Info
DT Modulation1	Diethylstilbestrol inhibits the reaction SLC2A1 protein affects the transport of Glucose			[10]
Regulation Mechanism				Transcription Factor Info
DT Modulation2	Diethylstilbestrol results in decreased activity of SLC2A1 protein			[10]
Regulation Mechanism				Transcription Factor Info
DT Modulation1	Tamoxifen inhibits the reaction SLC2A1 protein affects the transport of Glucose			[10]
Regulation Mechanism				Transcription Factor Info
DT Modulation2	Tamoxifen results in decreased activity of SLC2A1 protein			[10]
Regulation Mechanism				Transcription Factor Info
DT Modulation1	Progesterone co-treated with Bucladesine results in increased expression of SLC2A1 protein			[123]
Regulation Mechanism				Transcription Factor Info
DT Modulation2	Progesterone co-treated with Estradiol results in decreased expression of SLC2A1 protein			[11]
Regulation Mechanism				Transcription Factor Info
DT Modulation1	Fluorouracil results in decreased activity of SLC2A1 protein			[13]
Regulation Mechanism				Transcription Factor Info
DT Modulation2	Fluorouracil results in increased expression of SLC2A1 mRNA			[153]
Regulation Mechanism				Transcription Factor Info
DT Modulation1	Ciprofloxacin affects the localization of SLC2A1 mRNA			[14]
Regulation Mechanism				Transcription Factor Info
DT Modulation1	Ofloxacin affects the localization of SLC2A1 mRNA			[14]
Regulation Mechanism				Transcription Factor Info
DT Modulation1	Hydrogen Peroxide affects the expression of SLC2A1 mRNA			[17]
Regulation Mechanism				Transcription Factor Info
DT Modulation1	Doxorubicin results in increased expression of SLC2A1 mRNA			[153]
Regulation Mechanism				Transcription Factor Info
DT Modulation1	Cyclosporine results in increased expression of SLC2A1 mRNA			[25]
Regulation Mechanism				Transcription Factor Info
DT Modulation1	Cisplatin co-treated with eprenetapopt promotes the reaction Oxygen deficiency results in increased expression of SLC2A1 mRNA			[28]
Regulation Mechanism				Transcription Factor Info
DT Modulation2	Cisplatin co-treated with jinfukang results in increased expression of SLC2A1 mRNA			[62]
Regulation Mechanism				Transcription Factor Info
DT Modulation3	Cisplatin results in increased expression of SLC2A1 mRNA			[25]
Regulation Mechanism				Transcription Factor Info
DT Modulation4	Oxygen deficiency inhibits the reaction Cisplatin results in decreased expression of SLC2A1 mRNA			[28]
Regulation Mechanism				Transcription Factor Info
DT Modulation1	Rotenone inhibits the reaction Oxygen deficiency results in increased expression of SLC2A1 mRNA			[97]
Regulation Mechanism				Transcription Factor Info
DT Modulation2	SLC2A1 protein inhibits the reaction Rotenone results in increased activity of MAPK8 protein			[173]
Regulation Mechanism				Transcription Factor Info
DT Modulation3	SLC2A1 protein results in decreased susceptibility to Rotenone			[173]
Regulation Mechanism				Transcription Factor Info
DT Modulation1	AKT1 protein affects the reaction Arsenic Trioxide affects the localization of SLC2A1 protein			[38]
Regulation Mechanism				Transcription Factor Info
DT Modulation2	Arsenic Trioxide affects the localization of SLC2A1 protein			[38]
Regulation Mechanism				Transcription Factor Info
DT Modulation3	Arsenic Trioxide promotes the reaction Ascorbic Acid results in decreased expression of SLC2A1 mRNA			[109]
Regulation Mechanism				Transcription Factor Info
DT Modulation4	Arsenic Trioxide promotes the reaction Ascorbic Acid results in decreased expression of SLC2A1 protein			[109]
Regulation Mechanism				Transcription Factor Info
DT Modulation5	Arsenic Trioxide results in decreased expression of SLC2A1 mRNA			[109]
Regulation Mechanism				Transcription Factor Info
DT Modulation6	Arsenic Trioxide results in decreased expression of SLC2A1 protein			[109]
Regulation Mechanism				Transcription Factor Info
DT Modulation7	Ascorbic Acid co-treated with Arsenic Trioxide results in decreased expression of SLC2A1 protein			[109]
Regulation Mechanism				Transcription Factor Info
DT Modulation8	Ascorbic Acid promotes the reaction Arsenic Trioxide results in decreased expression of SLC2A1 mRNA			[109]
Regulation Mechanism				Transcription Factor Info
DT Modulation9	Ascorbic Acid promotes the reaction Arsenic Trioxide results in decreased expression of SLC2A1 protein			[109]
Regulation Mechanism				Transcription Factor Info
DT Modulation10	BAY-876 inhibits the reaction Arsenic Trioxide affects the localization of SLC2A1 protein			[38]
Regulation Mechanism				Transcription Factor Info
DT Modulation11	SLC2A1 protein results in increased import of Arsenic Trioxide			[110]
Regulation Mechanism				Transcription Factor Info
DT Modulation1	cobaltous chloride inhibits the reaction Valproic Acid inhibits the reaction Colforsin results in increased expression of SLC2A1 protein			[132]
Regulation Mechanism				Transcription Factor Info
DT Modulation2	Valproic Acid inhibits the reaction Colforsin results in increased expression of SLC2A1 protein			[132]
Regulation Mechanism				Transcription Factor Info
DT Modulation3	Valproic Acid inhibits the reaction SLC2A1 protein results in increased transport of Glucose			[129]
Regulation Mechanism				Transcription Factor Info
DT Modulation4	Valproic Acid results in increased expression of SLC2A1 mRNA			[167]
Regulation Mechanism				Transcription Factor Info
Aluminum	1 DT Activity Modulations Related to This Exogenous Factor		Click to Show/Hide the Full List
DT Modulation1	Aluminum increases the expression of SLC2A1			[44]
Regulation Mechanism	via enhancement of Hypoxia-inducible factor 1-alpha (HIF1A)			Transcription Factor Info
Cell System	Human hepatoblastoma cells (HepG2)
DT Modulation1	Genistein inhibits the reaction SLC2A1 protein affects the transport of Glucose			[10]
Regulation Mechanism				Transcription Factor Info
DT Modulation2	Genistein results in decreased activity of SLC2A1 protein			[10]
Regulation Mechanism				Transcription Factor Info
DT Modulation1	7-hydroxyflavone inhibits the reaction SLC2A1 protein affects the transport of Glucose			[10]
Regulation Mechanism				Transcription Factor Info
DT Modulation2	7-hydroxyflavone results in decreased activity of SLC2A1 protein			[10]
Regulation Mechanism				Transcription Factor Info
DT Modulation1	Phloretin inhibits the reaction SLC2A1 protein affects the transport of Glucose			[10]
Regulation Mechanism				Transcription Factor Info
DT Modulation2	Phloretin results in decreased activity of SLC2A1 protein			[10]
Regulation Mechanism				Transcription Factor Info
DT Modulation1	7-hydroxyflavone inhibits the reaction SLC2A1 protein affects the transport of Glucose			[10]
Regulation Mechanism				Transcription Factor Info
DT Modulation2	Barbiturates inhibits the reaction SLC2A1 protein results in increased transport of Glucose			[129]
Regulation Mechanism				Transcription Factor Info
DT Modulation3	bisphenol A results in increased activity of and affects the localization of SLC2A1 protein which results in increased uptake of Glucose			[119]
Regulation Mechanism				Transcription Factor Info
DT Modulation4	Chloral Hydrate inhibits the reaction SLC2A1 protein results in increased transport of Glucose			[129]
Regulation Mechanism				Transcription Factor Info
DT Modulation5	Cyclofenil inhibits the reaction SLC2A1 protein affects the transport of Glucose			[10]
Regulation Mechanism				Transcription Factor Info
DT Modulation6	Cytochalasin B inhibits the reaction SLC2A1 protein results in increased transport of Glucose			[145]
Regulation Mechanism				Transcription Factor Info
DT Modulation7	daidzein inhibits the reaction SLC2A1 protein affects the transport of Glucose			[10]
Regulation Mechanism				Transcription Factor Info
DT Modulation8	Deoxyglucose results in increased abundance of Glucose which affects the localization of SLC2A1 protein			[108]
Regulation Mechanism				Transcription Factor Info
DT Modulation9	Diazepam inhibits the reaction SLC2A1 protein results in increased transport of Glucose			[129]
Regulation Mechanism				Transcription Factor Info
DT Modulation10	Diethylstilbestrol inhibits the reaction SLC2A1 protein affects the transport of Glucose			[10]
Regulation Mechanism				Transcription Factor Info
DT Modulation11	Genistein inhibits the reaction SLC2A1 protein affects the transport of Glucose			[10]
Regulation Mechanism				Transcription Factor Info
DT Modulation12	Glucose results in increased stability of SLC2A1 protein			[101]
Regulation Mechanism				Transcription Factor Info
DT Modulation13	isoliquiritigenin inhibits the reaction SLC2A1 protein affects the transport of Glucose			[10]
Regulation Mechanism				Transcription Factor Info
DT Modulation14	kaempferol inhibits the reaction SLC2A1 protein affects the transport of Glucose			[10]
Regulation Mechanism				Transcription Factor Info
DT Modulation15	myricetin inhibits the reaction SLC2A1 protein affects the transport of Glucose			[10]
Regulation Mechanism				Transcription Factor Info
DT Modulation16	naringenin inhibits the reaction SLC2A1 protein affects the transport of Glucose			[10]
Regulation Mechanism				Transcription Factor Info
DT Modulation17	Phloretin inhibits the reaction SLC2A1 protein affects the transport of Glucose			[10]
Regulation Mechanism				Transcription Factor Info
DT Modulation18	PRNP protein results in increased expression of SLC2A1 protein which results in increased uptake of Glucose			[160]
Regulation Mechanism				Transcription Factor Info
DT Modulation19	Quercetin inhibits the reaction SLC2A1 protein affects the transport of Glucose			[10]
Regulation Mechanism				Transcription Factor Info
DT Modulation20	Resveratrol inhibits the reaction SLC2A1 protein results in increased uptake of Glucose			[161]
Regulation Mechanism				Transcription Factor Info
DT Modulation21	SLC2A1 protein results in increased transport of Glucose			[129]
Regulation Mechanism				Transcription Factor Info
DT Modulation22	SLC2A1 protein results in increased uptake of Glucose			[161]
Regulation Mechanism				Transcription Factor Info
DT Modulation23	sodium arsenite results in increased abundance of Arsenic inhibits the reaction Deoxyglucose results in increased abundance of Glucose which affects the localization of SLC2A1 protein			[108]
Regulation Mechanism				Transcription Factor Info
DT Modulation24	Tamoxifen inhibits the reaction SLC2A1 protein affects the transport of Glucose			[10]
Regulation Mechanism				Transcription Factor Info
DT Modulation25	Valproic Acid inhibits the reaction SLC2A1 protein results in increased transport of Glucose			[129]
Regulation Mechanism				Transcription Factor Info
DT Modulation1	Benzo(a)pyrene affects the expression of SLC2A1 mRNA			[113]
Regulation Mechanism				Transcription Factor Info
DT Modulation2	Benzo(a)pyrene affects the methylation of SLC2A1 3' UTR			[114]
Regulation Mechanism				Transcription Factor Info
DT Modulation3	Benzo(a)pyrene affects the methylation of SLC2A1 promoter			[114]
Regulation Mechanism				Transcription Factor Info
DT Modulation4	Benzo(a)pyrene results in increased expression of SLC2A1 mRNA			[115]
Regulation Mechanism				Transcription Factor Info
DT Modulation1	Flame Retardants results in increased abundance of tris(1,3-dichloro-2-propyl)phosphate which results in increased expression of SLC2A1 protein			[185]
Regulation Mechanism				Transcription Factor Info
DT Modulation1	NOG protein co-treated with Phenylmercuric Acetate co-treated with dorsomorphin co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide results in increased expression of SLC2A1 mRNA			[26]
Regulation Mechanism				Transcription Factor Info
DT Modulation1	Diethylhexyl Phthalate results in increased expression of SLC2A1 mRNA			[69]
Regulation Mechanism				Transcription Factor Info
103D5R	1 DT Activity Modulations Related to This Exogenous Factor		Click to Show/Hide the Full List
DT Modulation1	103D5R results in decreased expression of SLC2A1 mRNA			[79]
Regulation Mechanism				Transcription Factor Info
1,2,5,6-dibenzanthracene	1 DT Activity Modulations Related to This Exogenous Factor		Click to Show/Hide the Full List
DT Modulation1	1,2,5,6-dibenzanthracene results in increased expression of SLC2A1 mRNA			[80]
Regulation Mechanism				Transcription Factor Info
1,2-diethyl-3-hydroxypyridin-4-one	1 DT Activity Modulations Related to This Exogenous Factor		Click to Show/Hide the Full List
DT Modulation1	1,2-diethyl-3-hydroxypyridin-4-one results in increased expression of SLC2A1 mRNA			[81]
Regulation Mechanism				Transcription Factor Info
2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one	5 DT Activity Modulations Related to This Exogenous Factor		Click to Show/Hide the Full List
DT Modulation1	2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction cobaltous chloride results in increased expression of SLC2A1 protein			[82]
Regulation Mechanism				Transcription Factor Info
DT Modulation2	2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction DDT results in increased expression of SLC2A1 mRNA			[83]
Regulation Mechanism				Transcription Factor Info
DT Modulation3	2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction Oxygen deficiency results in increased expression of SLC2A1 protein			[82]
Regulation Mechanism				Transcription Factor Info
DT Modulation4	PTEN protein inhibits the reaction 2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction Oxygen deficiency results in increased expression of SLC2A1 protein			[82]
Regulation Mechanism				Transcription Factor Info
DT Modulation5	PTEN protein promotes the reaction 2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction cobaltous chloride results in increased expression of SLC2A1 protein			[82]
Regulation Mechanism				Transcription Factor Info
2,3',4,4',5-pentachlorobiphenyl	4 DT Activity Modulations Related to This Exogenous Factor		Click to Show/Hide the Full List
DT Modulation1	2,3',4,4',5-pentachlorobiphenyl results in increased expression of SLC2A1 mRNA			[84]
Regulation Mechanism				Transcription Factor Info
DT Modulation2	Acetylcysteine inhibits the reaction 2,3',4,4',5-pentachlorobiphenyl results in increased expression of SLC2A1 mRNA			[84]
Regulation Mechanism				Transcription Factor Info
DT Modulation3	AHR protein affects the reaction 2,3',4,4',5-pentachlorobiphenyl results in increased expression of SLC2A1 mRNA			[85]
Regulation Mechanism				Transcription Factor Info
DT Modulation4	PKM protein affects the reaction 2,3',4,4',5-pentachlorobiphenyl results in increased expression of SLC2A1 mRNA			[85]
Regulation Mechanism				Transcription Factor Info
2,4,5,2',4',5'-hexachlorobiphenyl	2 DT Activity Modulations Related to This Exogenous Factor		Click to Show/Hide the Full List
DT Modulation1	2,4,5,2',4',5'-hexachlorobiphenyl results in increased expression of SLC2A1 mRNA			[84]
Regulation Mechanism				Transcription Factor Info
DT Modulation2	Acetylcysteine inhibits the reaction 2,4,5,2',4',5'-hexachlorobiphenyl results in increased expression of SLC2A1 mRNA			[84]
Regulation Mechanism				Transcription Factor Info
2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one	6 DT Activity Modulations Related to This Exogenous Factor		Click to Show/Hide the Full List
DT Modulation1	2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one inhibits the reaction cobaltous chloride results in increased expression of SLC2A1 protein			[82]
Regulation Mechanism				Transcription Factor Info
DT Modulation2	2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one inhibits the reaction Oxygen deficiency results in increased expression of SLC2A1 protein			[82]
Regulation Mechanism				Transcription Factor Info
DT Modulation3	2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one promotes the reaction fosbretabulin analog results in decreased expression of SLC2A1 protein			[76]
Regulation Mechanism				Transcription Factor Info
DT Modulation4	2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one results in decreased expression of SLC2A1 protein			[76]
Regulation Mechanism				Transcription Factor Info
DT Modulation5	PTEN protein inhibits the reaction 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one inhibits the reaction Oxygen deficiency results in increased expression of SLC2A1 protein			[82]
Regulation Mechanism				Transcription Factor Info
DT Modulation6	PTEN protein promotes the reaction 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one inhibits the reaction cobaltous chloride results in increased expression of SLC2A1 protein			[82]
Regulation Mechanism				Transcription Factor Info
2-amino-3-(4'-N,N-bis(2-chloroethyl)amino)phenylpropionic acid N-oxide	1 DT Activity Modulations Related to This Exogenous Factor		Click to Show/Hide the Full List
DT Modulation1	2-amino-3-(4'-N,N-bis(2-chloroethyl)amino)phenylpropionic acid N-oxide inhibits the reaction nickel chloride results in increased expression of SLC2A1 mRNA			[86]
Regulation Mechanism				Transcription Factor Info
2-(N-(7-nitrobenz-2-oxa-1,3-diazol-4-yl)amino)-2-deoxyglucose	10 DT Activity Modulations Related to This Exogenous Factor		Click to Show/Hide the Full List
DT Modulation1	Apigenin inhibits the reaction SLC2A1 protein results in increased uptake of 2-(N-(7-nitrobenz-2-oxa-1,3-diazol-4-yl)amino)-2-deoxyglucose			[87]
Regulation Mechanism				Transcription Factor Info
DT Modulation2	eupatilin inhibits the reaction SLC2A1 protein results in increased uptake of 2-(N-(7-nitrobenz-2-oxa-1,3-diazol-4-yl)amino)-2-deoxyglucose			[87]
Regulation Mechanism				Transcription Factor Info
DT Modulation3	hispidulin inhibits the reaction SLC2A1 protein results in increased uptake of 2-(N-(7-nitrobenz-2-oxa-1,3-diazol-4-yl)amino)-2-deoxyglucose			[87]
Regulation Mechanism				Transcription Factor Info
DT Modulation4	kaempferol inhibits the reaction SLC2A1 protein results in increased uptake of 2-(N-(7-nitrobenz-2-oxa-1,3-diazol-4-yl)amino)-2-deoxyglucose			[87]
Regulation Mechanism				Transcription Factor Info
DT Modulation5	Luteolin inhibits the reaction SLC2A1 protein results in increased uptake of 2-(N-(7-nitrobenz-2-oxa-1,3-diazol-4-yl)amino)-2-deoxyglucose			[87]
Regulation Mechanism				Transcription Factor Info
DT Modulation6	nobiletin inhibits the reaction SLC2A1 protein results in increased uptake of 2-(N-(7-nitrobenz-2-oxa-1,3-diazol-4-yl)amino)-2-deoxyglucose			[87]
Regulation Mechanism				Transcription Factor Info
DT Modulation7	Quercetin inhibits the reaction SLC2A1 protein results in increased uptake of 2-(N-(7-nitrobenz-2-oxa-1,3-diazol-4-yl)amino)-2-deoxyglucose			[87]
Regulation Mechanism				Transcription Factor Info
DT Modulation8	sinensetin inhibits the reaction SLC2A1 protein results in increased uptake of 2-(N-(7-nitrobenz-2-oxa-1,3-diazol-4-yl)amino)-2-deoxyglucose			[87]
Regulation Mechanism				Transcription Factor Info
DT Modulation9	SLC2A1 protein results in increased uptake of 2-(N-(7-nitrobenz-2-oxa-1,3-diazol-4-yl)amino)-2-deoxyglucose			[87]
Regulation Mechanism				Transcription Factor Info
DT Modulation10	WZB117 inhibits the reaction SLC2A1 protein results in increased uptake of 2-(N-(7-nitrobenz-2-oxa-1,3-diazol-4-yl)amino)-2-deoxyglucose			[87]
Regulation Mechanism				Transcription Factor Info
3,4,5,3',4'-pentachlorobiphenyl	2 DT Activity Modulations Related to This Exogenous Factor		Click to Show/Hide the Full List
DT Modulation1	3,4,5,3',4'-pentachlorobiphenyl results in increased expression of SLC2A1 mRNA			[84]
Regulation Mechanism				Transcription Factor Info
DT Modulation2	Acetylcysteine inhibits the reaction 3,4,5,3',4'-pentachlorobiphenyl results in increased expression of SLC2A1 mRNA			[84]
Regulation Mechanism				Transcription Factor Info
3-deazaneplanocin	1 DT Activity Modulations Related to This Exogenous Factor		Click to Show/Hide the Full List
DT Modulation1	3-deazaneplanocin results in decreased expression of SLC2A1 protein			[88]
Regulation Mechanism				Transcription Factor Info
3-methyladenine	5 DT Activity Modulations Related to This Exogenous Factor		Click to Show/Hide the Full List
DT Modulation1	3-methyladenine inhibits the reaction Cadmium Chloride results in increased abundance of Cadmium which results in increased expression of SLC2A1 protein			[89]
Regulation Mechanism				Transcription Factor Info
DT Modulation2	3-methyladenine inhibits the reaction Potassium Dichromate results in increased expression of SLC2A1 protein			[90]
Regulation Mechanism				Transcription Factor Info
DT Modulation3	3-methyladenine promotes the reaction Silybin results in decreased expression of SLC2A1 protein			[91]
Regulation Mechanism				Transcription Factor Info
DT Modulation4	3-methyladenine results in decreased expression of SLC2A1 protein			[92]
Regulation Mechanism				Transcription Factor Info
DT Modulation5	4,6-dimorpholino-N-(4-nitrophenyl)-1,3,5-triazin-2-amine inhibits the reaction 3-methyladenine results in decreased expression of SLC2A1 protein			[92]
Regulation Mechanism				Transcription Factor Info
3-O-Methylglucose	6 DT Activity Modulations Related to This Exogenous Factor		Click to Show/Hide the Full List
DT Modulation1	Pentobarbital inhibits the reaction SLC2A1 protein results in increased uptake of 3-O-Methylglucose			[7]
Regulation Mechanism				Transcription Factor Info
DT Modulation2	Pentobarbital promotes the reaction SLC2A1 gene polymorphism results in decreased uptake of 3-O-Methylglucose			[7]
Regulation Mechanism				Transcription Factor Info
DT Modulation3	Phenobarbital inhibits the reaction SLC2A1 protein results in increased uptake of 3-O-Methylglucose			[7]
Regulation Mechanism				Transcription Factor Info
DT Modulation4	Phenobarbital promotes the reaction SLC2A1 gene polymorphism results in decreased uptake of 3-O-Methylglucose			[7]
Regulation Mechanism				Transcription Factor Info
DT Modulation5	SLC2A1 protein mutant form results in decreased transport of 3-O-Methylglucose			[93]
Regulation Mechanism				Transcription Factor Info
DT Modulation6	SLC2A1 protein results in increased uptake of 3-O-Methylglucose			[7]
Regulation Mechanism				Transcription Factor Info
4-(4-(3-(pyridin-2-yl)-1H-pyrazol-4-yl)pyridin-2-yl)-N-(tetrahydro-2H-pyran-4-yl)benzamide	1 DT Activity Modulations Related to This Exogenous Factor		Click to Show/Hide the Full List
DT Modulation1	4-(4-(3-(pyridin-2-yl)-1H-pyrazol-4-yl)pyridin-2-yl)-N-(tetrahydro-2H-pyran-4-yl)benzamide results in decreased expression of SLC2A1 mRNA			[37]
Regulation Mechanism				Transcription Factor Info
4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide	3 DT Activity Modulations Related to This Exogenous Factor		Click to Show/Hide the Full List
DT Modulation1	LDN 193189 co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide co-treated with FGF2 protein results in decreased expression of SLC2A1 protein			[94]
Regulation Mechanism				Transcription Factor Info
DT Modulation2	NOG protein co-treated with p-Chloromercuribenzoic Acid co-treated with dorsomorphin co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide results in decreased expression of SLC2A1 mRNA			[26]
Regulation Mechanism				Transcription Factor Info
DT Modulation3	NOG protein co-treated with Phenylmercuric Acetate co-treated with dorsomorphin co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide results in increased expression of SLC2A1 mRNA			[26]
Regulation Mechanism				Transcription Factor Info
4,6-dimorpholino-N-(4-nitrophenyl)-1,3,5-triazin-2-amine	4 DT Activity Modulations Related to This Exogenous Factor		Click to Show/Hide the Full List
DT Modulation1	4,6-dimorpholino-N-(4-nitrophenyl)-1,3,5-triazin-2-amine inhibits the reaction 3-methyladenine results in decreased expression of SLC2A1 protein			[92]
Regulation Mechanism				Transcription Factor Info
DT Modulation2	4,6-dimorpholino-N-(4-nitrophenyl)-1,3,5-triazin-2-amine inhibits the reaction MPC1 protein results in decreased expression of SLC2A1 protein			[95]
Regulation Mechanism				Transcription Factor Info
DT Modulation3	4,6-dimorpholino-N-(4-nitrophenyl)-1,3,5-triazin-2-amine results in increased expression of SLC2A1 protein			[96]
Regulation Mechanism				Transcription Factor Info
DT Modulation4	Curcumin inhibits the reaction 4,6-dimorpholino-N-(4-nitrophenyl)-1,3,5-triazin-2-amine results in increased phosphorylation of SLC2A1 protein			[96]
Regulation Mechanism				Transcription Factor Info
4'-O-methylalpinumisoflavone	1 DT Activity Modulations Related to This Exogenous Factor		Click to Show/Hide the Full List
DT Modulation1	4'-O-methylalpinumisoflavone inhibits the reaction Oxygen deficiency results in increased expression of SLC2A1 mRNA			[97]
Regulation Mechanism				Transcription Factor Info
4-phenylbutyric acid	1 DT Activity Modulations Related to This Exogenous Factor		Click to Show/Hide the Full List
DT Modulation1	4-phenylbutyric acid inhibits the reaction Potassium Dichromate results in increased expression of SLC2A1 protein			[90]
Regulation Mechanism				Transcription Factor Info
7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide	1 DT Activity Modulations Related to This Exogenous Factor		Click to Show/Hide the Full List
DT Modulation1	7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide results in increased expression of SLC2A1 mRNA			[98]
Regulation Mechanism				Transcription Factor Info
abrine	1 DT Activity Modulations Related to This Exogenous Factor		Click to Show/Hide the Full List
DT Modulation1	abrine results in increased expression of SLC2A1 mRNA			[99]
Regulation Mechanism				Transcription Factor Info
acadesine	1 DT Activity Modulations Related to This Exogenous Factor		Click to Show/Hide the Full List
DT Modulation1	acadesine results in increased expression of SLC2A1 mRNA			[49]
Regulation Mechanism				Transcription Factor Info
Acetylcysteine	5 DT Activity Modulations Related to This Exogenous Factor		Click to Show/Hide the Full List
DT Modulation1	Acetylcysteine inhibits the reaction 2,3',4,4',5-pentachlorobiphenyl results in increased expression of SLC2A1 mRNA			[84]
Regulation Mechanism				Transcription Factor Info
DT Modulation2	Acetylcysteine inhibits the reaction 2,4,5,2',4',5'-hexachlorobiphenyl results in increased expression of SLC2A1 mRNA			[84]
Regulation Mechanism				Transcription Factor Info
DT Modulation3	Acetylcysteine inhibits the reaction 3,4,5,3',4'-pentachlorobiphenyl results in increased expression of SLC2A1 mRNA			[84]
Regulation Mechanism				Transcription Factor Info
DT Modulation4	Acetylcysteine inhibits the reaction DDT results in increased expression of SLC2A1 mRNA			[83]
Regulation Mechanism				Transcription Factor Info
DT Modulation5	Acetylcysteine inhibits the reaction icaritin results in decreased expression of SLC2A1 protein			[100]
Regulation Mechanism				Transcription Factor Info
Adenosine Triphosphate	1 DT Activity Modulations Related to This Exogenous Factor		Click to Show/Hide the Full List
DT Modulation1	Adenosine Triphosphate results in decreased stability of SLC2A1 protein			[101]
Regulation Mechanism				Transcription Factor Info
alpha-naphthoflavone	2 DT Activity Modulations Related to This Exogenous Factor		Click to Show/Hide the Full List
DT Modulation1	alpha-naphthoflavone inhibits the reaction Tetrachlorodibenzodioxin results in decreased expression of SLC2A1 mRNA			[55]
Regulation Mechanism				Transcription Factor Info
DT Modulation2	alpha-naphthoflavone results in increased expression of SLC2A1 mRNA			[55]
Regulation Mechanism				Transcription Factor Info
ammonium 2,3,3,3-tetrafluoro-2-(heptafluoropropoxy)-propanoate	1 DT Activity Modulations Related to This Exogenous Factor		Click to Show/Hide the Full List
DT Modulation1	ammonium 2,3,3,3-tetrafluoro-2-(heptafluoropropoxy)-propanoate results in decreased expression of SLC2A1 mRNA			[103]
Regulation Mechanism				Transcription Factor Info
annonacin	1 DT Activity Modulations Related to This Exogenous Factor		Click to Show/Hide the Full List
DT Modulation1	annonacin inhibits the reaction Oxygen deficiency results in increased expression of SLC2A1 mRNA			[104]
Regulation Mechanism				Transcription Factor Info
apaziquone	1 DT Activity Modulations Related to This Exogenous Factor		Click to Show/Hide the Full List
DT Modulation1	SLC2A1 protein results in decreased susceptibility to apaziquone			[105]
Regulation Mechanism				Transcription Factor Info
Apigenin	3 DT Activity Modulations Related to This Exogenous Factor		Click to Show/Hide the Full List
DT Modulation1	Apigenin inhibits the reaction SLC2A1 protein results in increased uptake of 2-(N-(7-nitrobenz-2-oxa-1,3-diazol-4-yl)amino)-2-deoxyglucose			[87]
Regulation Mechanism				Transcription Factor Info
DT Modulation2	Apigenin results in decreased expression of SLC2A1 mRNA			[106]
Regulation Mechanism				Transcription Factor Info
DT Modulation3	Apigenin results in decreased expression of SLC2A1 protein			[106]
Regulation Mechanism				Transcription Factor Info
aristolochic acid I	1 DT Activity Modulations Related to This Exogenous Factor		Click to Show/Hide the Full List
DT Modulation1	aristolochic acid I results in decreased expression of SLC2A1 mRNA			[107]
Regulation Mechanism				Transcription Factor Info
arsenic trichloride	1 DT Activity Modulations Related to This Exogenous Factor		Click to Show/Hide the Full List
DT Modulation1	arsenic trichloride co-treated with Ascorbic Acid results in decreased expression of SLC2A1 mRNA			[109]
Regulation Mechanism				Transcription Factor Info
Asbestos, Serpentine	1 DT Activity Modulations Related to This Exogenous Factor		Click to Show/Hide the Full List
DT Modulation1	Asbestos, Serpentine results in increased expression of SLC2A1 mRNA			[111]
Regulation Mechanism				Transcription Factor Info
Ascorbic Acid	9 DT Activity Modulations Related to This Exogenous Factor		Click to Show/Hide the Full List
DT Modulation1	arsenic trichloride co-treated with Ascorbic Acid results in decreased expression of SLC2A1 mRNA			[109]
Regulation Mechanism				Transcription Factor Info
DT Modulation2	Arsenic Trioxide promotes the reaction Ascorbic Acid results in decreased expression of SLC2A1 mRNA			[109]
Regulation Mechanism				Transcription Factor Info
DT Modulation3	Arsenic Trioxide promotes the reaction Ascorbic Acid results in decreased expression of SLC2A1 protein			[109]
Regulation Mechanism				Transcription Factor Info
DT Modulation4	Ascorbic Acid affects the expression of SLC2A1 protein			[109]
Regulation Mechanism				Transcription Factor Info
DT Modulation5	Ascorbic Acid co-treated with Arsenic Trioxide results in decreased expression of SLC2A1 protein			[109]
Regulation Mechanism				Transcription Factor Info
DT Modulation6	Ascorbic Acid promotes the reaction Arsenic Trioxide results in decreased expression of SLC2A1 mRNA			[109]
Regulation Mechanism				Transcription Factor Info
DT Modulation7	Ascorbic Acid promotes the reaction Arsenic Trioxide results in decreased expression of SLC2A1 protein			[109]
Regulation Mechanism				Transcription Factor Info
DT Modulation8	Ascorbic Acid results in decreased expression of SLC2A1 mRNA			[109]
Regulation Mechanism				Transcription Factor Info
DT Modulation9	Ascorbic Acid results in decreased expression of SLC2A1 protein			[109]
Regulation Mechanism				Transcription Factor Info
azaspiracid	1 DT Activity Modulations Related to This Exogenous Factor		Click to Show/Hide the Full List
DT Modulation1	azaspiracid results in increased expression of SLC2A1 mRNA			[65]
Regulation Mechanism				Transcription Factor Info
BAY-876	2 DT Activity Modulations Related to This Exogenous Factor		Click to Show/Hide the Full List
DT Modulation1	BAY-876 affects the localization of SLC2A1 protein			[38]
Regulation Mechanism				Transcription Factor Info
DT Modulation2	BAY-876 inhibits the reaction Arsenic Trioxide affects the localization of SLC2A1 protein			[38]
Regulation Mechanism				Transcription Factor Info
beauvericin	1 DT Activity Modulations Related to This Exogenous Factor		Click to Show/Hide the Full List
DT Modulation1	beauvericin co-treated with enniatins results in increased expression of SLC2A1 protein			[112]
Regulation Mechanism				Transcription Factor Info
Benztropine	1 DT Activity Modulations Related to This Exogenous Factor		Click to Show/Hide the Full List
DT Modulation1	Benztropine results in decreased expression of SLC2A1 protein			[35]
Regulation Mechanism				Transcription Factor Info
benzyloxycarbonylleucyl-leucyl-leucine aldehyde	1 DT Activity Modulations Related to This Exogenous Factor		Click to Show/Hide the Full List
DT Modulation1	benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in increased expression of SLC2A1 protein			[43]
Regulation Mechanism				Transcription Factor Info
beta-lapachone	1 DT Activity Modulations Related to This Exogenous Factor		Click to Show/Hide the Full List
DT Modulation1	beta-lapachone results in increased expression of SLC2A1 mRNA			[116]
Regulation Mechanism				Transcription Factor Info
beta-Naphthoflavone	1 DT Activity Modulations Related to This Exogenous Factor		Click to Show/Hide the Full List
DT Modulation1	beta-Naphthoflavone results in decreased expression of SLC2A1 mRNA			[72]
Regulation Mechanism				Transcription Factor Info
bisphenol A	6 DT Activity Modulations Related to This Exogenous Factor		Click to Show/Hide the Full List
DT Modulation1	bisphenol A affects the expression of SLC2A1			[117]
Regulation Mechanism				Transcription Factor Info
DT Modulation2	bisphenol A affects the expression of SLC2A1 mRNA			[118]
Regulation Mechanism				Transcription Factor Info
DT Modulation3	bisphenol A results in increased activity of and affects the localization of SLC2A1 protein			[119]
Regulation Mechanism				Transcription Factor Info
DT Modulation4	bisphenol A results in increased activity of and affects the localization of SLC2A1 protein which results in increased uptake of Glucose			[119]
Regulation Mechanism				Transcription Factor Info
DT Modulation5	bisphenol A results in increased expression of SLC2A1 mRNA			[120]
Regulation Mechanism				Transcription Factor Info
DT Modulation6	bisphenol A results in increased expression of SLC2A1 protein			[119]
Regulation Mechanism				Transcription Factor Info
bisphenol S	1 DT Activity Modulations Related to This Exogenous Factor		Click to Show/Hide the Full List
DT Modulation1	bisphenol S results in decreased expression of SLC2A1 mRNA			[121]
Regulation Mechanism				Transcription Factor Info
bruceine D	3 DT Activity Modulations Related to This Exogenous Factor		Click to Show/Hide the Full List
DT Modulation1	bruceine D affects the reaction Oxygen deficiency affects the expression of SLC2A1 protein			[122]
Regulation Mechanism				Transcription Factor Info
DT Modulation2	bruceine D results in decreased expression of SLC2A1 protein			[122]
Regulation Mechanism				Transcription Factor Info
DT Modulation3	CTNNBIP1 protein affects the reaction bruceine D affects the reaction Oxygen deficiency affects the expression of SLC2A1 protein			[122]
Regulation Mechanism				Transcription Factor Info
Bucladesine	1 DT Activity Modulations Related to This Exogenous Factor		Click to Show/Hide the Full List
DT Modulation1	Progesterone co-treated with Bucladesine results in increased expression of SLC2A1 protein			[123]
Regulation Mechanism				Transcription Factor Info
Butyric Acid	4 DT Activity Modulations Related to This Exogenous Factor		Click to Show/Hide the Full List
DT Modulation1	Butyric Acid results in decreased expression of SLC2A1 mRNA			[124]
Regulation Mechanism				Transcription Factor Info
DT Modulation2	Butyric Acid results in decreased expression of SLC2A1 protein			[124]
Regulation Mechanism				Transcription Factor Info
DT Modulation3	SIRT4 protein affects the reaction Butyric Acid results in decreased expression of SLC2A1 mRNA			[124]
Regulation Mechanism				Transcription Factor Info
DT Modulation4	SIRT4 protein affects the reaction Butyric Acid results in decreased expression of SLC2A1 protein			[124]
Regulation Mechanism				Transcription Factor Info
Cacodylic Acid	1 DT Activity Modulations Related to This Exogenous Factor		Click to Show/Hide the Full List
DT Modulation1	Cacodylic Acid results in decreased expression of SLC2A1 mRNA			[125]
Regulation Mechanism				Transcription Factor Info
Cadmium Chloride	7 DT Activity Modulations Related to This Exogenous Factor		Click to Show/Hide the Full List
DT Modulation1	3-methyladenine inhibits the reaction Cadmium Chloride results in increased abundance of Cadmium which results in increased expression of SLC2A1 protein			[89]
Regulation Mechanism				Transcription Factor Info
DT Modulation2	Cadmium Chloride results in decreased expression of SLC2A1 mRNA			[47]
Regulation Mechanism				Transcription Factor Info
DT Modulation3	Cadmium Chloride results in increased abundance of Cadmium which results in increased expression of SLC2A1 protein			[89]
Regulation Mechanism				Transcription Factor Info
DT Modulation4	Cadmium Chloride results in increased expression of SLC2A1 mRNA			[126]
Regulation Mechanism				Transcription Factor Info
DT Modulation5	Carbonyl Cyanide m-Chlorophenyl Hydrazone inhibits the reaction Cadmium Chloride results in increased abundance of Cadmium which results in increased expression of SLC2A1 protein			[89]
Regulation Mechanism				Transcription Factor Info
DT Modulation6	HMGA2 protein affects the reaction Cadmium Chloride results in increased abundance of Cadmium which results in increased expression of SLC2A1 protein			[89]
Regulation Mechanism				Transcription Factor Info
DT Modulation7	Sirolimus inhibits the reaction Cadmium Chloride results in increased abundance of Cadmium which results in increased expression of SLC2A1 protein			[92]
Regulation Mechanism				Transcription Factor Info
Carbonyl Cyanide m-Chlorophenyl Hydrazone	1 DT Activity Modulations Related to This Exogenous Factor		Click to Show/Hide the Full List
DT Modulation1	Carbonyl Cyanide m-Chlorophenyl Hydrazone inhibits the reaction Cadmium Chloride results in increased abundance of Cadmium which results in increased expression of SLC2A1 protein			[89]
Regulation Mechanism				Transcription Factor Info
Chloral Hydrate	1 DT Activity Modulations Related to This Exogenous Factor		Click to Show/Hide the Full List
DT Modulation1	Chloral Hydrate inhibits the reaction SLC2A1 protein results in increased transport of Glucose			[129]
Regulation Mechanism				Transcription Factor Info
chloroacetaldehyde	1 DT Activity Modulations Related to This Exogenous Factor		Click to Show/Hide the Full List
DT Modulation1	chloroacetaldehyde results in increased expression of SLC2A1 mRNA			[25]
Regulation Mechanism				Transcription Factor Info
chloropicrin	2 DT Activity Modulations Related to This Exogenous Factor		Click to Show/Hide the Full List
DT Modulation1	chloropicrin affects the expression of SLC2A1 mRNA			[130]
Regulation Mechanism				Transcription Factor Info
DT Modulation2	chloropicrin results in decreased expression of SLC2A1 mRNA			[64]
Regulation Mechanism				Transcription Factor Info
chromium hexavalent ion	3 DT Activity Modulations Related to This Exogenous Factor		Click to Show/Hide the Full List
DT Modulation1	chromium hexavalent ion results in increased expression of SLC2A1 mRNA			[131]
Regulation Mechanism				Transcription Factor Info
DT Modulation2	chromium hexavalent ion results in increased expression of SLC2A1 protein			[95]
Regulation Mechanism				Transcription Factor Info
DT Modulation3	MPC1 protein inhibits the reaction chromium hexavalent ion results in increased expression of SLC2A1 protein			[95]
Regulation Mechanism				Transcription Factor Info
cobaltous chloride	11 DT Activity Modulations Related to This Exogenous Factor		Click to Show/Hide the Full List
DT Modulation1	2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction cobaltous chloride results in increased expression of SLC2A1 protein			[82]
Regulation Mechanism				Transcription Factor Info
DT Modulation2	2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one inhibits the reaction cobaltous chloride results in increased expression of SLC2A1 protein			[82]
Regulation Mechanism				Transcription Factor Info
DT Modulation3	cobaltous chloride inhibits the reaction Valproic Acid inhibits the reaction Colforsin results in increased expression of SLC2A1 protein			[132]
Regulation Mechanism				Transcription Factor Info
DT Modulation4	cobaltous chloride results in decreased abundance of Oxygen which results in increased expression of SLC2A1 protein			[43]
Regulation Mechanism				Transcription Factor Info
DT Modulation5	cobaltous chloride results in increased expression of SLC2A1 mRNA			[133]
Regulation Mechanism				Transcription Factor Info
DT Modulation6	cobaltous chloride results in increased expression of SLC2A1 protein			[134]
Regulation Mechanism				Transcription Factor Info
DT Modulation7	L-4F peptide inhibits the reaction cobaltous chloride results in increased expression of SLC2A1 mRNA			[135]
Regulation Mechanism				Transcription Factor Info
DT Modulation8	PTEN protein promotes the reaction 2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction cobaltous chloride results in increased expression of SLC2A1 protein			[82]
Regulation Mechanism				Transcription Factor Info
DT Modulation9	PTEN protein promotes the reaction 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one inhibits the reaction cobaltous chloride results in increased expression of SLC2A1 protein			[82]
Regulation Mechanism				Transcription Factor Info
DT Modulation10	tetraethylenepentamine inhibits the reaction cobaltous chloride results in increased expression of SLC2A1 mRNA			[136]
Regulation Mechanism				Transcription Factor Info
DT Modulation11	zinc chloride inhibits the reaction cobaltous chloride results in increased expression of SLC2A1 mRNA			[137]
Regulation Mechanism				Transcription Factor Info
cobalt oxide	1 DT Activity Modulations Related to This Exogenous Factor		Click to Show/Hide the Full List
DT Modulation1	cobalt oxide analog results in increased expression of SLC2A1 mRNA			[138]
Regulation Mechanism				Transcription Factor Info
Colforsin	3 DT Activity Modulations Related to This Exogenous Factor		Click to Show/Hide the Full List
DT Modulation1	cobaltous chloride inhibits the reaction Valproic Acid inhibits the reaction Colforsin results in increased expression of SLC2A1 protein			[132]
Regulation Mechanism				Transcription Factor Info
DT Modulation2	Colforsin results in increased expression of SLC2A1 protein			[132]
Regulation Mechanism				Transcription Factor Info
DT Modulation3	Valproic Acid inhibits the reaction Colforsin results in increased expression of SLC2A1 protein			[132]
Regulation Mechanism				Transcription Factor Info
Copper	3 DT Activity Modulations Related to This Exogenous Factor		Click to Show/Hide the Full List
DT Modulation1	Chelating Agents binds to Copper which results in increased expression of SLC2A1 mRNA			[139]
Regulation Mechanism				Transcription Factor Info
DT Modulation2	NSC 689534 binds to Copper which results in increased expression of SLC2A1 mRNA			[140]
Regulation Mechanism				Transcription Factor Info
DT Modulation3	Organoselenium Compounds binds to Copper which results in increased expression of SLC2A1 mRNA			[141]
Regulation Mechanism				Transcription Factor Info
cupric chloride	1 DT Activity Modulations Related to This Exogenous Factor		Click to Show/Hide the Full List
DT Modulation1	cupric chloride results in increased expression of SLC2A1 mRNA			[5]
Regulation Mechanism				Transcription Factor Info
Cyclofenil	2 DT Activity Modulations Related to This Exogenous Factor		Click to Show/Hide the Full List
DT Modulation1	Cyclofenil inhibits the reaction SLC2A1 protein affects the transport of Glucose			[10]
Regulation Mechanism				Transcription Factor Info
DT Modulation2	Cyclofenil results in decreased activity of SLC2A1 protein			[10]
Regulation Mechanism				Transcription Factor Info
Cycloheximide	1 DT Activity Modulations Related to This Exogenous Factor		Click to Show/Hide the Full List
DT Modulation1	Tetrachlorodibenzodioxin co-treated with Cycloheximide results in increased expression of SLC2A1 mRNA			[142]
Regulation Mechanism				Transcription Factor Info
Cytochalasin B	3 DT Activity Modulations Related to This Exogenous Factor		Click to Show/Hide the Full List
DT Modulation1	Cytochalasin B affects the folding of SLC2A1 protein			[143]
Regulation Mechanism				Transcription Factor Info
DT Modulation2	Cytochalasin B binds to and results in decreased activity of SLC2A1 protein			[144]
Regulation Mechanism				Transcription Factor Info
DT Modulation3	Cytochalasin B inhibits the reaction SLC2A1 protein results in increased transport of Glucose			[145]
Regulation Mechanism				Transcription Factor Info
Dacarbazine	1 DT Activity Modulations Related to This Exogenous Factor		Click to Show/Hide the Full List
DT Modulation1	SLC2A1 protein results in decreased susceptibility to Dacarbazine			[105]
Regulation Mechanism				Transcription Factor Info
daidzein	2 DT Activity Modulations Related to This Exogenous Factor		Click to Show/Hide the Full List
DT Modulation1	daidzein inhibits the reaction SLC2A1 protein affects the transport of Glucose			[10]
Regulation Mechanism				Transcription Factor Info
DT Modulation2	daidzein results in decreased activity of SLC2A1 protein			[10]
Regulation Mechanism				Transcription Factor Info
Deferoxamine	4 DT Activity Modulations Related to This Exogenous Factor		Click to Show/Hide the Full List
DT Modulation1	Deferoxamine inhibits the reaction myricetin inhibits the reaction Formaldehyde results in increased expression of SLC2A1 mRNA			[77]
Regulation Mechanism				Transcription Factor Info
DT Modulation2	Deferoxamine inhibits the reaction myricetin inhibits the reaction Formaldehyde results in increased expression of SLC2A1 protein			[77]
Regulation Mechanism				Transcription Factor Info
DT Modulation3	Deferoxamine results in decreased abundance of Oxygen which results in increased expression of SLC2A1 protein			[43]
Regulation Mechanism				Transcription Factor Info
DT Modulation4	Deferoxamine results in increased expression of SLC2A1 mRNA			[133]
Regulation Mechanism				Transcription Factor Info
deguelin	1 DT Activity Modulations Related to This Exogenous Factor		Click to Show/Hide the Full List
DT Modulation1	deguelin results in increased expression of SLC2A1 mRNA			[74]
Regulation Mechanism				Transcription Factor Info
Dehydroascorbic Acid	2 DT Activity Modulations Related to This Exogenous Factor		Click to Show/Hide the Full List
DT Modulation1	SLC2A1 mRNA affects the uptake of Dehydroascorbic Acid			[146]
Regulation Mechanism				Transcription Factor Info
DT Modulation2	SLC2A1 protein mutant form results in decreased transport of Dehydroascorbic Acid			[93]
Regulation Mechanism				Transcription Factor Info
Deoxyglucose	4 DT Activity Modulations Related to This Exogenous Factor		Click to Show/Hide the Full List
DT Modulation1	Deoxyglucose results in increased abundance of Glucose which affects the localization of SLC2A1 protein			[108]
Regulation Mechanism				Transcription Factor Info
DT Modulation2	SLC2A1 protein inhibits the reaction INS protein results in increased uptake of Deoxyglucose			[147]
Regulation Mechanism				Transcription Factor Info
DT Modulation3	SLC2A1 protein results in increased uptake of Deoxyglucose			[147]
Regulation Mechanism				Transcription Factor Info
DT Modulation4	sodium arsenite results in increased abundance of Arsenic inhibits the reaction Deoxyglucose results in increased abundance of Glucose which affects the localization of SLC2A1 protein			[108]
Regulation Mechanism				Transcription Factor Info
deoxynivalenol	1 DT Activity Modulations Related to This Exogenous Factor		Click to Show/Hide the Full List
DT Modulation1	deoxynivalenol results in decreased expression of SLC2A1 protein			[148]
Regulation Mechanism				Transcription Factor Info
diallyl trisulfide	1 DT Activity Modulations Related to This Exogenous Factor		Click to Show/Hide the Full List
DT Modulation1	diallyl trisulfide results in decreased expression of SLC2A1 mRNA			[149]
Regulation Mechanism				Transcription Factor Info
Diazepam	1 DT Activity Modulations Related to This Exogenous Factor		Click to Show/Hide the Full List
DT Modulation1	Diazepam inhibits the reaction SLC2A1 protein results in increased transport of Glucose			[129]
Regulation Mechanism				Transcription Factor Info
Dichlorodiphenyl Dichloroethylene	1 DT Activity Modulations Related to This Exogenous Factor		Click to Show/Hide the Full List
DT Modulation1	Dichlorodiphenyl Dichloroethylene results in decreased expression of SLC2A1 mRNA			[150]
Regulation Mechanism				Transcription Factor Info
dicrotophos	1 DT Activity Modulations Related to This Exogenous Factor		Click to Show/Hide the Full List
DT Modulation1	dicrotophos results in increased expression of SLC2A1 mRNA			[63]
Regulation Mechanism				Transcription Factor Info
dihydrotanshinone I	1 DT Activity Modulations Related to This Exogenous Factor		Click to Show/Hide the Full List
DT Modulation1	dihydrotanshinone I inhibits the reaction Oxygen deficiency results in increased expression of SLC2A1 protein			[151]
Regulation Mechanism				Transcription Factor Info
di-n-butylphosphoric acid	1 DT Activity Modulations Related to This Exogenous Factor		Click to Show/Hide the Full List
DT Modulation1	di-n-butylphosphoric acid affects the expression of SLC2A1 mRNA			[152]
Regulation Mechanism				Transcription Factor Info
dorsomorphin	3 DT Activity Modulations Related to This Exogenous Factor		Click to Show/Hide the Full List
DT Modulation1	dorsomorphin promotes the reaction Silybin results in decreased expression of SLC2A1 protein			[91]
Regulation Mechanism				Transcription Factor Info
DT Modulation2	NOG protein co-treated with p-Chloromercuribenzoic Acid co-treated with dorsomorphin co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide results in decreased expression of SLC2A1 mRNA			[26]
Regulation Mechanism				Transcription Factor Info
DT Modulation3	NOG protein co-treated with Phenylmercuric Acetate co-treated with dorsomorphin co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide results in increased expression of SLC2A1 mRNA			[26]
Regulation Mechanism				Transcription Factor Info
Drupanin	1 DT Activity Modulations Related to This Exogenous Factor		Click to Show/Hide the Full List
DT Modulation1	Drupanin results in decreased expression of SLC2A1 mRNA			[154]
Regulation Mechanism				Transcription Factor Info
enniatins	1 DT Activity Modulations Related to This Exogenous Factor		Click to Show/Hide the Full List
DT Modulation1	beauvericin co-treated with enniatins results in increased expression of SLC2A1 protein			[112]
Regulation Mechanism				Transcription Factor Info
epigallocatechin gallate	1 DT Activity Modulations Related to This Exogenous Factor		Click to Show/Hide the Full List
DT Modulation1	potassium chromate(VI) co-treated with epigallocatechin gallate results in increased expression of SLC2A1 mRNA			[155]
Regulation Mechanism				Transcription Factor Info
eprenetapopt	2 DT Activity Modulations Related to This Exogenous Factor		Click to Show/Hide the Full List
DT Modulation1	Cisplatin co-treated with eprenetapopt promotes the reaction Oxygen deficiency results in increased expression of SLC2A1 mRNA			[28]
Regulation Mechanism				Transcription Factor Info
DT Modulation2	eprenetapopt promotes the reaction Oxygen deficiency results in increased expression of SLC2A1 mRNA			[28]
Regulation Mechanism				Transcription Factor Info
Ethanol	1 DT Activity Modulations Related to This Exogenous Factor		Click to Show/Hide the Full List
DT Modulation1	Ethanol co-treated with Folic Acid results in increased expression of SLC2A1 mRNA			[156]
Regulation Mechanism				Transcription Factor Info
eupatilin	1 DT Activity Modulations Related to This Exogenous Factor		Click to Show/Hide the Full List
DT Modulation1	eupatilin inhibits the reaction SLC2A1 protein results in increased uptake of 2-(N-(7-nitrobenz-2-oxa-1,3-diazol-4-yl)amino)-2-deoxyglucose			[87]
Regulation Mechanism				Transcription Factor Info
Fenbendazole	2 DT Activity Modulations Related to This Exogenous Factor		Click to Show/Hide the Full List
DT Modulation1	Fenbendazole analog results in decreased expression of SLC2A1 mRNA			[157]
Regulation Mechanism				Transcription Factor Info
DT Modulation2	Fenbendazole results in decreased expression of SLC2A1 mRNA			[157]
Regulation Mechanism				Transcription Factor Info
Fluorodeoxyglucose F18	1 DT Activity Modulations Related to This Exogenous Factor		Click to Show/Hide the Full List
DT Modulation1	SLC2A1 mRNA affects the uptake of Fluorodeoxyglucose F18			[153]
Regulation Mechanism				Transcription Factor Info
Folic Acid	1 DT Activity Modulations Related to This Exogenous Factor		Click to Show/Hide the Full List
DT Modulation1	Ethanol co-treated with Folic Acid results in increased expression of SLC2A1 mRNA			[156]
Regulation Mechanism				Transcription Factor Info
fosbretabulin	2 DT Activity Modulations Related to This Exogenous Factor		Click to Show/Hide the Full List
DT Modulation1	2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one promotes the reaction fosbretabulin analog results in decreased expression of SLC2A1 protein			[76]
Regulation Mechanism				Transcription Factor Info
DT Modulation2	fosbretabulin analog results in decreased expression of SLC2A1 protein			[76]
Regulation Mechanism				Transcription Factor Info
Furaldehyde	1 DT Activity Modulations Related to This Exogenous Factor		Click to Show/Hide the Full List
DT Modulation1	Sodium Chloride co-treated with Furaldehyde results in decreased expression of and affects the localization of SLC2A1 protein			[158]
Regulation Mechanism				Transcription Factor Info
genipin	1 DT Activity Modulations Related to This Exogenous Factor		Click to Show/Hide the Full List
DT Modulation1	genipin inhibits the reaction Oxygen deficiency results in increased expression of SLC2A1 mRNA			[159]
Regulation Mechanism				Transcription Factor Info
glycidyl methacrylate	1 DT Activity Modulations Related to This Exogenous Factor		Click to Show/Hide the Full List
DT Modulation1	glycidyl methacrylate results in increased expression of SLC2A1 protein			[162]
Regulation Mechanism				Transcription Factor Info
gossypol acetic acid	1 DT Activity Modulations Related to This Exogenous Factor		Click to Show/Hide the Full List
DT Modulation1	gossypol acetic acid results in increased expression of SLC2A1 protein			[163]
Regulation Mechanism				Transcription Factor Info
GSK3235025	1 DT Activity Modulations Related to This Exogenous Factor		Click to Show/Hide the Full List
DT Modulation1	GSK3235025 results in decreased expression of SLC2A1 protein			[164]
Regulation Mechanism				Transcription Factor Info
Hexoses	1 DT Activity Modulations Related to This Exogenous Factor		Click to Show/Hide the Full List
DT Modulation1	Resveratrol binds to SLC2A1 protein which results in decreased transport of Hexoses			[161]
Regulation Mechanism				Transcription Factor Info
hispidulin	1 DT Activity Modulations Related to This Exogenous Factor		Click to Show/Hide the Full List
DT Modulation1	hispidulin inhibits the reaction SLC2A1 protein results in increased uptake of 2-(N-(7-nitrobenz-2-oxa-1,3-diazol-4-yl)amino)-2-deoxyglucose			[87]
Regulation Mechanism				Transcription Factor Info
icaritin	5 DT Activity Modulations Related to This Exogenous Factor		Click to Show/Hide the Full List
DT Modulation1	Acetylcysteine inhibits the reaction icaritin results in decreased expression of SLC2A1 protein			[100]
Regulation Mechanism				Transcription Factor Info
DT Modulation2	icaritin results in decreased expression of SLC2A1 mRNA			[100]
Regulation Mechanism				Transcription Factor Info
DT Modulation3	icaritin results in decreased expression of SLC2A1 protein			[100]
Regulation Mechanism				Transcription Factor Info
DT Modulation4	pifithrin inhibits the reaction icaritin results in decreased expression of SLC2A1 mRNA			[100]
Regulation Mechanism				Transcription Factor Info
DT Modulation5	pifithrin inhibits the reaction icaritin results in decreased expression of SLC2A1 protein			[100]
Regulation Mechanism				Transcription Factor Info
isoliquiritigenin	2 DT Activity Modulations Related to This Exogenous Factor		Click to Show/Hide the Full List
DT Modulation1	isoliquiritigenin inhibits the reaction SLC2A1 protein affects the transport of Glucose			[10]
Regulation Mechanism				Transcription Factor Info
DT Modulation2	isoliquiritigenin results in decreased activity of SLC2A1 protein			[10]
Regulation Mechanism				Transcription Factor Info
kaempferide	1 DT Activity Modulations Related to This Exogenous Factor		Click to Show/Hide the Full List
DT Modulation1	kaempferide results in decreased expression of SLC2A1 mRNA			[154]
Regulation Mechanism				Transcription Factor Info
kaempferol	4 DT Activity Modulations Related to This Exogenous Factor		Click to Show/Hide the Full List
DT Modulation1	kaempferol inhibits the reaction SLC2A1 protein affects the transport of Glucose			[10]
Regulation Mechanism				Transcription Factor Info
DT Modulation2	kaempferol inhibits the reaction SLC2A1 protein results in increased uptake of 2-(N-(7-nitrobenz-2-oxa-1,3-diazol-4-yl)amino)-2-deoxyglucose			[87]
Regulation Mechanism				Transcription Factor Info
DT Modulation3	kaempferol results in decreased activity of SLC2A1 protein			[10]
Regulation Mechanism				Transcription Factor Info
DT Modulation4	kaempferol results in decreased expression of SLC2A1 mRNA			[59]
Regulation Mechanism				Transcription Factor Info
LDN 193189	1 DT Activity Modulations Related to This Exogenous Factor		Click to Show/Hide the Full List
DT Modulation1	LDN 193189 co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide co-treated with FGF2 protein results in decreased expression of SLC2A1 protein			[94]
Regulation Mechanism				Transcription Factor Info
lead acetate	4 DT Activity Modulations Related to This Exogenous Factor		Click to Show/Hide the Full List
DT Modulation1	lead acetate results in increased abundance of Lead which results in decreased expression of SLC2A1 mRNA			[165]
Regulation Mechanism				Transcription Factor Info
DT Modulation2	lead acetate results in increased abundance of Lead which results in decreased expression of SLC2A1 protein			[165]
Regulation Mechanism				Transcription Factor Info
DT Modulation3	PPIF protein affects the reaction lead acetate results in increased abundance of Lead which results in decreased expression of SLC2A1 mRNA			[165]
Regulation Mechanism				Transcription Factor Info
DT Modulation4	PPIF protein affects the reaction lead acetate results in increased abundance of Lead which results in decreased expression of SLC2A1 protein			[165]
Regulation Mechanism				Transcription Factor Info
Luteolin	1 DT Activity Modulations Related to This Exogenous Factor		Click to Show/Hide the Full List
DT Modulation1	Luteolin inhibits the reaction SLC2A1 protein results in increased uptake of 2-(N-(7-nitrobenz-2-oxa-1,3-diazol-4-yl)amino)-2-deoxyglucose			[87]
Regulation Mechanism				Transcription Factor Info
Mebendazole	2 DT Activity Modulations Related to This Exogenous Factor		Click to Show/Hide the Full List
DT Modulation1	Mebendazole binds to SLC2A1 protein			[166]
Regulation Mechanism				Transcription Factor Info
DT Modulation2	Mebendazole results in decreased expression of SLC2A1 mRNA			[166]
Regulation Mechanism				Transcription Factor Info
methylmercuric chloride	1 DT Activity Modulations Related to This Exogenous Factor		Click to Show/Hide the Full List
DT Modulation1	methylmercuric chloride results in decreased expression of SLC2A1 mRNA			[167]
Regulation Mechanism				Transcription Factor Info
Methyl Methanesulfonate	1 DT Activity Modulations Related to This Exogenous Factor		Click to Show/Hide the Full List
DT Modulation1	Methyl Methanesulfonate results in decreased expression of SLC2A1 mRNA			[57]
Regulation Mechanism				Transcription Factor Info
Mimosine	1 DT Activity Modulations Related to This Exogenous Factor		Click to Show/Hide the Full List
DT Modulation1	Mimosine results in increased expression of SLC2A1 mRNA			[168]
Regulation Mechanism				Transcription Factor Info
Minocycline	1 DT Activity Modulations Related to This Exogenous Factor		Click to Show/Hide the Full List
DT Modulation1	Minocycline inhibits the reaction Oxygen deficiency results in increased expression of SLC2A1 mRNA			[169]
Regulation Mechanism				Transcription Factor Info
mono-(2-ethylhexyl)phthalate	1 DT Activity Modulations Related to This Exogenous Factor		Click to Show/Hide the Full List
DT Modulation1	mono-(2-ethylhexyl)phthalate results in decreased expression of SLC2A1 protein			[170]
Regulation Mechanism				Transcription Factor Info
monobutyl phthalate	1 DT Activity Modulations Related to This Exogenous Factor		Click to Show/Hide the Full List
DT Modulation1	monobutyl phthalate results in increased expression of SLC2A1 protein			[170]
Regulation Mechanism				Transcription Factor Info
monomethylarsonic acid	2 DT Activity Modulations Related to This Exogenous Factor		Click to Show/Hide the Full List
DT Modulation1	monomethylarsonic acid results in decreased expression of SLC2A1 mRNA			[125]
Regulation Mechanism				Transcription Factor Info
DT Modulation2	SLC2A1 protein results in increased import of monomethylarsonic acid			[110]
Regulation Mechanism				Transcription Factor Info
monomethylarsonous acid	1 DT Activity Modulations Related to This Exogenous Factor		Click to Show/Hide the Full List
DT Modulation1	monomethylarsonous acid results in decreased expression of SLC2A1 mRNA			[125]
Regulation Mechanism				Transcription Factor Info
MRK 003	1 DT Activity Modulations Related to This Exogenous Factor		Click to Show/Hide the Full List
DT Modulation1	MRK 003 results in decreased expression of SLC2A1 protein			[50]
Regulation Mechanism				Transcription Factor Info
myricetin	6 DT Activity Modulations Related to This Exogenous Factor		Click to Show/Hide the Full List
DT Modulation1	Deferoxamine inhibits the reaction myricetin inhibits the reaction Formaldehyde results in increased expression of SLC2A1 mRNA			[77]
Regulation Mechanism				Transcription Factor Info
DT Modulation2	Deferoxamine inhibits the reaction myricetin inhibits the reaction Formaldehyde results in increased expression of SLC2A1 protein			[77]
Regulation Mechanism				Transcription Factor Info
DT Modulation3	myricetin inhibits the reaction Formaldehyde results in increased expression of SLC2A1 mRNA			[77]
Regulation Mechanism				Transcription Factor Info
DT Modulation4	myricetin inhibits the reaction Formaldehyde results in increased expression of SLC2A1 protein			[77]
Regulation Mechanism				Transcription Factor Info
DT Modulation5	myricetin inhibits the reaction SLC2A1 protein affects the transport of Glucose			[10]
Regulation Mechanism				Transcription Factor Info
DT Modulation6	myricetin results in decreased activity of SLC2A1 protein			[10]
Regulation Mechanism				Transcription Factor Info
naringenin	2 DT Activity Modulations Related to This Exogenous Factor		Click to Show/Hide the Full List
DT Modulation1	naringenin inhibits the reaction SLC2A1 protein affects the transport of Glucose			[10]
Regulation Mechanism				Transcription Factor Info
DT Modulation2	naringenin results in decreased activity of SLC2A1 protein			[10]
Regulation Mechanism				Transcription Factor Info
nickel chloride	2 DT Activity Modulations Related to This Exogenous Factor		Click to Show/Hide the Full List
DT Modulation1	2-amino-3-(4'-N,N-bis(2-chloroethyl)amino)phenylpropionic acid N-oxide inhibits the reaction nickel chloride results in increased expression of SLC2A1 mRNA			[86]
Regulation Mechanism				Transcription Factor Info
DT Modulation2	nickel chloride results in increased expression of SLC2A1 mRNA			[86]
Regulation Mechanism				Transcription Factor Info
nobiletin	1 DT Activity Modulations Related to This Exogenous Factor		Click to Show/Hide the Full List
DT Modulation1	nobiletin inhibits the reaction SLC2A1 protein results in increased uptake of 2-(N-(7-nitrobenz-2-oxa-1,3-diazol-4-yl)amino)-2-deoxyglucose			[87]
Regulation Mechanism				Transcription Factor Info
NSC 689534	1 DT Activity Modulations Related to This Exogenous Factor		Click to Show/Hide the Full List
DT Modulation1	NSC 689534 binds to Copper which results in increased expression of SLC2A1 mRNA			[140]
Regulation Mechanism				Transcription Factor Info
Oleic Acid	1 DT Activity Modulations Related to This Exogenous Factor		Click to Show/Hide the Full List
DT Modulation1	Palmitic Acid co-treated with Oleic Acid co-treated with TNF protein affects the expression of SLC2A1 mRNA			[172]
Regulation Mechanism				Transcription Factor Info
Oxygen	26 DT Activity Modulations Related to This Exogenous Factor		Click to Show/Hide the Full List
DT Modulation1	2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction Oxygen deficiency results in increased expression of SLC2A1 protein			[82]
Regulation Mechanism				Transcription Factor Info
DT Modulation2	2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one inhibits the reaction Oxygen deficiency results in increased expression of SLC2A1 protein			[82]
Regulation Mechanism				Transcription Factor Info
DT Modulation3	4'-O-methylalpinumisoflavone inhibits the reaction Oxygen deficiency results in increased expression of SLC2A1 mRNA			[97]
Regulation Mechanism				Transcription Factor Info
DT Modulation4	annonacin inhibits the reaction Oxygen deficiency results in increased expression of SLC2A1 mRNA			[104]
Regulation Mechanism				Transcription Factor Info
DT Modulation5	bruceine D affects the reaction Oxygen deficiency affects the expression of SLC2A1 protein			[122]
Regulation Mechanism				Transcription Factor Info
DT Modulation6	Cisplatin co-treated with eprenetapopt promotes the reaction Oxygen deficiency results in increased expression of SLC2A1 mRNA			[28]
Regulation Mechanism				Transcription Factor Info
DT Modulation7	cobaltous chloride results in decreased abundance of Oxygen which results in increased expression of SLC2A1 protein			[43]
Regulation Mechanism				Transcription Factor Info
DT Modulation8	CTNNBIP1 protein affects the reaction bruceine D affects the reaction Oxygen deficiency affects the expression of SLC2A1 protein			[122]
Regulation Mechanism				Transcription Factor Info
DT Modulation9	Deferoxamine results in decreased abundance of Oxygen which results in increased expression of SLC2A1 protein			[43]
Regulation Mechanism				Transcription Factor Info
DT Modulation10	dihydrotanshinone I inhibits the reaction Oxygen deficiency results in increased expression of SLC2A1 protein			[151]
Regulation Mechanism				Transcription Factor Info
DT Modulation11	eprenetapopt promotes the reaction Oxygen deficiency results in increased expression of SLC2A1 mRNA			[28]
Regulation Mechanism				Transcription Factor Info
DT Modulation12	genipin inhibits the reaction Oxygen deficiency results in increased expression of SLC2A1 mRNA			[159]
Regulation Mechanism				Transcription Factor Info
DT Modulation13	HIF1A protein affects the reaction Oxygen deficiency results in increased expression of SLC2A1 protein			[43]
Regulation Mechanism				Transcription Factor Info
DT Modulation14	Minocycline inhibits the reaction Oxygen deficiency results in increased expression of SLC2A1 mRNA			[169]
Regulation Mechanism				Transcription Factor Info
DT Modulation15	Oxygen deficiency affects the expression of SLC2A1 protein			[122]
Regulation Mechanism				Transcription Factor Info
DT Modulation16	Oxygen deficiency inhibits the reaction Cisplatin results in decreased expression of SLC2A1 mRNA			[28]
Regulation Mechanism				Transcription Factor Info
DT Modulation17	Oxygen deficiency results in increased expression of SLC2A1 mRNA			[173]
Regulation Mechanism				Transcription Factor Info
DT Modulation18	Oxygen deficiency results in increased expression of SLC2A1 protein			[134]
Regulation Mechanism				Transcription Factor Info
DT Modulation19	Polyphenols inhibits the reaction Oxygen deficiency results in increased expression of SLC2A1 mRNA			[174]
Regulation Mechanism				Transcription Factor Info
DT Modulation20	Propolis inhibits the reaction Oxygen deficiency results in increased expression of SLC2A1 mRNA			[174]
Regulation Mechanism				Transcription Factor Info
DT Modulation21	PTEN protein inhibits the reaction 2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction Oxygen deficiency results in increased expression of SLC2A1 protein			[82]
Regulation Mechanism				Transcription Factor Info
DT Modulation22	PTEN protein inhibits the reaction 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one inhibits the reaction Oxygen deficiency results in increased expression of SLC2A1 protein			[82]
Regulation Mechanism				Transcription Factor Info
DT Modulation23	Rotenone inhibits the reaction Oxygen deficiency results in increased expression of SLC2A1 mRNA			[97]
Regulation Mechanism				Transcription Factor Info
DT Modulation24	SLC2A1 protein inhibits the reaction Oxygen deficiency results in increased activity of MAPK8 protein			[173]
Regulation Mechanism				Transcription Factor Info
DT Modulation25	SLC2A1 protein results in decreased susceptibility to Oxygen deficiency			[173]
Regulation Mechanism				Transcription Factor Info
DT Modulation26	ST6GAL1 protein promotes the reaction Oxygen deficiency results in increased expression of SLC2A1 mRNA			[175]
Regulation Mechanism				Transcription Factor Info
Ozone	1 DT Activity Modulations Related to This Exogenous Factor		Click to Show/Hide the Full List
DT Modulation1	Ozone results in increased expression of SLC2A1 mRNA			[176]
Regulation Mechanism				Transcription Factor Info
Palmitic Acid	1 DT Activity Modulations Related to This Exogenous Factor		Click to Show/Hide the Full List
DT Modulation1	Palmitic Acid co-treated with Oleic Acid co-treated with TNF protein affects the expression of SLC2A1 mRNA			[172]
Regulation Mechanism				Transcription Factor Info
p-Chloromercuribenzoic Acid	2 DT Activity Modulations Related to This Exogenous Factor		Click to Show/Hide the Full List
DT Modulation1	NOG protein co-treated with p-Chloromercuribenzoic Acid co-treated with dorsomorphin co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide results in decreased expression of SLC2A1 mRNA			[26]
Regulation Mechanism				Transcription Factor Info
DT Modulation2	p-Chloromercuribenzoic Acid results in decreased expression of SLC2A1 mRNA			[61]
Regulation Mechanism				Transcription Factor Info
perfluorooctane sulfonic acid	1 DT Activity Modulations Related to This Exogenous Factor		Click to Show/Hide the Full List
DT Modulation1	perfluorooctane sulfonic acid results in decreased expression of SLC2A1 mRNA			[70]
Regulation Mechanism				Transcription Factor Info
perfluorooctanoic acid	1 DT Activity Modulations Related to This Exogenous Factor		Click to Show/Hide the Full List
DT Modulation1	perfluorooctanoic acid results in decreased expression of SLC2A1 mRNA			[70]
Regulation Mechanism				Transcription Factor Info
PF-06840003	2 DT Activity Modulations Related to This Exogenous Factor		Click to Show/Hide the Full List
DT Modulation1	PF-06840003 inhibits the reaction APP protein mutant form results in decreased expression of SLC2A1 mRNA			[177]
Regulation Mechanism				Transcription Factor Info
DT Modulation2	PF-06840003 inhibits the reaction MAPT protein mutant form results in decreased expression of SLC2A1 mRNA			[177]
Regulation Mechanism				Transcription Factor Info
pifithrin	2 DT Activity Modulations Related to This Exogenous Factor		Click to Show/Hide the Full List
DT Modulation1	pifithrin inhibits the reaction icaritin results in decreased expression of SLC2A1 mRNA			[100]
Regulation Mechanism				Transcription Factor Info
DT Modulation2	pifithrin inhibits the reaction icaritin results in decreased expression of SLC2A1 protein			[100]
Regulation Mechanism				Transcription Factor Info
potassium chromate(VI)	2 DT Activity Modulations Related to This Exogenous Factor		Click to Show/Hide the Full List
DT Modulation1	potassium chromate(VI) co-treated with epigallocatechin gallate results in increased expression of SLC2A1 mRNA			[155]
Regulation Mechanism				Transcription Factor Info
DT Modulation2	potassium chromate(VI) results in increased expression of SLC2A1 mRNA			[155]
Regulation Mechanism				Transcription Factor Info
Potassium Dichromate	4 DT Activity Modulations Related to This Exogenous Factor		Click to Show/Hide the Full List
DT Modulation1	3-methyladenine inhibits the reaction Potassium Dichromate results in increased expression of SLC2A1 protein			[90]
Regulation Mechanism				Transcription Factor Info
DT Modulation2	4-phenylbutyric acid inhibits the reaction Potassium Dichromate results in increased expression of SLC2A1 protein			[90]
Regulation Mechanism				Transcription Factor Info
DT Modulation3	ATF4 protein promotes the reaction Potassium Dichromate results in increased expression of SLC2A1 protein			[90]
Regulation Mechanism				Transcription Factor Info
DT Modulation4	Potassium Dichromate results in increased expression of SLC2A1 protein			[90]
Regulation Mechanism				Transcription Factor Info
prochloraz	1 DT Activity Modulations Related to This Exogenous Factor		Click to Show/Hide the Full List
DT Modulation1	prochloraz results in decreased expression of SLC2A1 mRNA			[68]
Regulation Mechanism				Transcription Factor Info
protoporphyrin IX	1 DT Activity Modulations Related to This Exogenous Factor		Click to Show/Hide the Full List
DT Modulation1	protoporphyrin IX results in decreased expression of SLC2A1 mRNA			[56]
Regulation Mechanism				Transcription Factor Info
pyrogallol 1,3-dimethyl ether	1 DT Activity Modulations Related to This Exogenous Factor		Click to Show/Hide the Full List
DT Modulation1	Sodium Chloride co-treated with pyrogallol 1,3-dimethyl ether results in increased expression of and affects the localization of SLC2A1 protein			[158]
Regulation Mechanism				Transcription Factor Info
quinone	1 DT Activity Modulations Related to This Exogenous Factor		Click to Show/Hide the Full List
DT Modulation1	HIF1A protein co-treated with quinone results in increased expression of SLC2A1 protein			[180]
Regulation Mechanism				Transcription Factor Info
roxadustat	1 DT Activity Modulations Related to This Exogenous Factor		Click to Show/Hide the Full List
DT Modulation1	roxadustat results in increased expression of SLC2A1 mRNA			[86]
Regulation Mechanism				Transcription Factor Info
Silybin	3 DT Activity Modulations Related to This Exogenous Factor		Click to Show/Hide the Full List
DT Modulation1	3-methyladenine promotes the reaction Silybin results in decreased expression of SLC2A1 protein			[91]
Regulation Mechanism				Transcription Factor Info
DT Modulation2	dorsomorphin promotes the reaction Silybin results in decreased expression of SLC2A1 protein			[91]
Regulation Mechanism				Transcription Factor Info
DT Modulation3	Silybin results in decreased expression of SLC2A1 protein			[91]
Regulation Mechanism				Transcription Factor Info
sinensetin	1 DT Activity Modulations Related to This Exogenous Factor		Click to Show/Hide the Full List
DT Modulation1	sinensetin inhibits the reaction SLC2A1 protein results in increased uptake of 2-(N-(7-nitrobenz-2-oxa-1,3-diazol-4-yl)amino)-2-deoxyglucose			[87]
Regulation Mechanism				Transcription Factor Info
Sirolimus	2 DT Activity Modulations Related to This Exogenous Factor		Click to Show/Hide the Full List
DT Modulation1	Sirolimus inhibits the reaction ATG4B protein results in increased expression of SLC2A1 protein			[92]
Regulation Mechanism				Transcription Factor Info
DT Modulation2	Sirolimus inhibits the reaction Cadmium Chloride results in increased abundance of Cadmium which results in increased expression of SLC2A1 protein			[92]
Regulation Mechanism				Transcription Factor Info
sodium arsenite	4 DT Activity Modulations Related to This Exogenous Factor		Click to Show/Hide the Full List
DT Modulation1	sodium arsenite results in decreased expression of SLC2A1 mRNA			[47]
Regulation Mechanism				Transcription Factor Info
DT Modulation2	sodium arsenite results in increased abundance of Arsenic inhibits the reaction Deoxyglucose results in increased abundance of Glucose which affects the localization of SLC2A1 protein			[108]
Regulation Mechanism				Transcription Factor Info
DT Modulation3	sodium arsenite results in increased abundance of arsenite which results in decreased expression of SLC2A1 mRNA			[125]
Regulation Mechanism				Transcription Factor Info
DT Modulation4	sodium arsenite results in increased expression of SLC2A1 mRNA			[181]
Regulation Mechanism				Transcription Factor Info
sodium bichromate	1 DT Activity Modulations Related to This Exogenous Factor		Click to Show/Hide the Full List
DT Modulation1	sodium bichromate results in decreased expression of SLC2A1 mRNA			[47]
Regulation Mechanism				Transcription Factor Info
Sodium Chloride	2 DT Activity Modulations Related to This Exogenous Factor		Click to Show/Hide the Full List
DT Modulation1	Sodium Chloride co-treated with Furaldehyde results in decreased expression of and affects the localization of SLC2A1 protein			[158]
Regulation Mechanism				Transcription Factor Info
DT Modulation2	Sodium Chloride co-treated with pyrogallol 1,3-dimethyl ether results in increased expression of and affects the localization of SLC2A1 protein			[158]
Regulation Mechanism				Transcription Factor Info
Tetrachlorodibenzodioxin	6 DT Activity Modulations Related to This Exogenous Factor		Click to Show/Hide the Full List
DT Modulation1	2-methyl-2H-pyrazole-3-carboxylic acid (2-methyl-4-o-tolylazophenyl)amide inhibits the reaction Tetrachlorodibenzodioxin results in decreased expression of SLC2A1 mRNA			[55]
Regulation Mechanism				Transcription Factor Info
DT Modulation2	alpha-naphthoflavone inhibits the reaction Tetrachlorodibenzodioxin results in decreased expression of SLC2A1 mRNA			[55]
Regulation Mechanism				Transcription Factor Info
DT Modulation3	Tetrachlorodibenzodioxin affects the expression of SLC2A1 mRNA			[182]
Regulation Mechanism				Transcription Factor Info
DT Modulation4	Tetrachlorodibenzodioxin co-treated with Cycloheximide results in increased expression of SLC2A1 mRNA			[142]
Regulation Mechanism				Transcription Factor Info
DT Modulation5	Tetrachlorodibenzodioxin results in decreased expression of SLC2A1 mRNA			[55]
Regulation Mechanism				Transcription Factor Info
DT Modulation6	Tetrachlorodibenzodioxin results in increased expression of SLC2A1 mRNA			[142]
Regulation Mechanism				Transcription Factor Info
tetraethylenepentamine	1 DT Activity Modulations Related to This Exogenous Factor		Click to Show/Hide the Full List
DT Modulation1	tetraethylenepentamine inhibits the reaction cobaltous chloride results in increased expression of SLC2A1 mRNA			[136]
Regulation Mechanism				Transcription Factor Info
tetrathiomolybdate	1 DT Activity Modulations Related to This Exogenous Factor		Click to Show/Hide the Full List
DT Modulation1	tetrathiomolybdate results in decreased expression of SLC2A1 mRNA			[183]
Regulation Mechanism				Transcription Factor Info
tolfenamic acid	1 DT Activity Modulations Related to This Exogenous Factor		Click to Show/Hide the Full List
DT Modulation1	tolfenamic acid affects the reaction TGFB1 protein affects the expression of SLC2A1 protein			[184]
Regulation Mechanism				Transcription Factor Info
trichostatin A	1 DT Activity Modulations Related to This Exogenous Factor		Click to Show/Hide the Full List
DT Modulation1	trichostatin A results in increased expression of SLC2A1 mRNA			[58]
Regulation Mechanism				Transcription Factor Info
Triiodothyronine	1 DT Activity Modulations Related to This Exogenous Factor		Click to Show/Hide the Full List
DT Modulation1	Triiodothyronine results in increased expression of SLC2A1 mRNA			[12]
Regulation Mechanism				Transcription Factor Info
triphenyl phosphate	1 DT Activity Modulations Related to This Exogenous Factor		Click to Show/Hide the Full List
DT Modulation1	Flame Retardants results in increased abundance of triphenyl phosphate which results in increased expression of SLC2A1 protein			[185]
Regulation Mechanism				Transcription Factor Info
tris(2-butoxyethyl) phosphate	1 DT Activity Modulations Related to This Exogenous Factor		Click to Show/Hide the Full List
DT Modulation1	tris(2-butoxyethyl) phosphate affects the expression of SLC2A1 mRNA			[186]
Regulation Mechanism				Transcription Factor Info
ubiquinone-O	2 DT Activity Modulations Related to This Exogenous Factor		Click to Show/Hide the Full List
DT Modulation1	ubiquinone-O results in decreased expression of SLC2A1 mRNA			[189]
Regulation Mechanism				Transcription Factor Info
DT Modulation2	ubiquinone-O results in decreased expression of SLC2A1 protein			[189]
Regulation Mechanism				Transcription Factor Info
Vanadates	1 DT Activity Modulations Related to This Exogenous Factor		Click to Show/Hide the Full List
DT Modulation1	Vanadates results in increased expression of SLC2A1 mRNA			[190]
Regulation Mechanism				Transcription Factor Info
Vanadium	1 DT Activity Modulations Related to This Exogenous Factor		Click to Show/Hide the Full List
DT Modulation1	Vanadium results in increased expression of SLC2A1 protein			[191]
Regulation Mechanism				Transcription Factor Info
Vincristine	1 DT Activity Modulations Related to This Exogenous Factor		Click to Show/Hide the Full List
DT Modulation1	SLC2A1 protein results in decreased susceptibility to Vincristine			[105]
Regulation Mechanism				Transcription Factor Info
Vitamin K 3	1 DT Activity Modulations Related to This Exogenous Factor		Click to Show/Hide the Full List
DT Modulation1	Vitamin K 3 affects the expression of SLC2A1 mRNA			[17]
Regulation Mechanism				Transcription Factor Info
warangalone	1 DT Activity Modulations Related to This Exogenous Factor		Click to Show/Hide the Full List
DT Modulation1	warangalone analog results in decreased expression of SLC2A1 protein			[192]
Regulation Mechanism				Transcription Factor Info
WZB117	1 DT Activity Modulations Related to This Exogenous Factor		Click to Show/Hide the Full List
DT Modulation1	WZB117 inhibits the reaction SLC2A1 protein results in increased uptake of 2-(N-(7-nitrobenz-2-oxa-1,3-diazol-4-yl)amino)-2-deoxyglucose			[87]
Regulation Mechanism				Transcription Factor Info
zinc chloride	1 DT Activity Modulations Related to This Exogenous Factor		Click to Show/Hide the Full List
DT Modulation1	zinc chloride inhibits the reaction cobaltous chloride results in increased expression of SLC2A1 mRNA			[137]
Regulation Mechanism				Transcription Factor Info

References
1	Caffeine inhibits glucose transport by binding at the GLUT1 nucleotide-binding site. Am J Physiol Cell Physiol. 2015 May 15;308(10):C827-34.
2	Discovery of dapagliflozin: a potent, selective renal sodium-dependent glucose cotransporter 2 (SGLT2) inhibitor for the treatment of type 2 diabetes. J Med Chem. 2008 Mar 13;51(5):1145-9.
3	Red wine and green tea flavonoids are cis-allosteric activators and competitive inhibitors of glucose transporter 1 (GLUT1)-mediated sugar uptake. J Biol Chem. 2018 Dec 21;293(51):19823-19834.
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