Detail Information of DT Wildtype Structure
| General Information of Drug Transporter (DT) | ||||||
|---|---|---|---|---|---|---|
| DT ID | DTD0400 Transporter Info | |||||
| Gene Name | SLC55A1 | |||||
| Transporter Name | Mitochondrial proton/calcium exchanger protein | |||||
| Gene ID | ||||||
| UniProt ID | ||||||
| Modelled Structures of This DT | ||||||
| Click to Save PDB File in TXT Format | ||||||
| Detail Information of Structural Model | ||||||
| Method | Homology modeling | |||||
| Template PDB | 3SKQ_A | Identity | 39.487% | |||
| Performance | Minimized Score | -545.51 kcal/mol | ||||
| Ramachandra Favored | Medium |
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| QMEANBrane Quality | Medium |
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| Ramachandran Plot |
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| Click to Save Ramachandran Plot in PNG Format | ||||||
| Ramz Z Score | -0.79 ±0.52 | |||||
| Residues in Favored Region | 183 | Ramachandran favored | 97.86% | |||
| Number of Outliers | 1 | Ramachandran outliers | 0.53% | |||
| Local Quality |
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| Click to Save Local Quality Plot in PNG Format | ||||||
| QMEANBrane Score | 0.78 | |||||
| AlphaFold Protein Structure Database | ||||||
| SWISS-MODEL Database | ||||||
| Experimental Structures of This DT | ||||||
| PDB ID | Scanning Method | Resolution | Expression System | Details | Ref | |
| 9BA1 | NMR | N.A. | Escherichia coli | [1] | ||
| Structure | ||||||
| Click to Save PDB File in TXT Format | ||||||
| References | ||||||
| 1 | An AI-informed NMR structure reveals an extraordinary LETM1 F-EF-hand domain that functions as a two-way regulator of mitochondrial calcium. Structure. 2024;32(11):2063-2082.e5. | |||||
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