General Information of Drug Transporter (DT)
DT ID	DTD0080 Transporter Info
Gene Name	SLC11A1
Transporter Name	Natural resistance-associated macrophage protein 1
Gene ID	6556
UniProt ID	P49279
Modelled Structures of This DT
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Detail Information of Structural Model
Method	Homology modeling
Template PDB	5M94_A		Identity	35.023%
Performance	Minimized Score	-1059.962 kcal/mol
	Ramachandra Favored	Medium
	QMEANBrane Quality	High
Ramachandran Plot
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	Ramz Z Score	-1.73 ±0.36
	Residues in Favored Region	415	Ramachandran favored	96.96%
	Number of Outliers	4	Ramachandran outliers	0.93%
Local Quality
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	QMEANBrane Score		0.82
AlphaFold Protein Structure Database	P49279 Click to jump to the details page
SWISS-MODEL Database	P49279 Click to jump to the details page
Experimental Structures of This DT
PDB ID	Scanning Method	Resolution	Expression System	Details	Ref
9F6P	EM	3.7 Å	Homo sapiens	Click to Show/Hide the Details	[1]
Structure
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Corresponding chain	A
Sequence Length	615		Mutation	No
9F6Q	EM	3.9 Å	Homo sapiens	Click to Show/Hide the Details	[1]
Structure
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Corresponding chain	A
Sequence Length	615		Mutation	No
References
1	Structural basis for metal ion transport by the human SLC11 proteins DMT1 and NRAMP1. Nat Commun. 2025;16(1):761.

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