General Information of Drug Transporter (DT)
DT ID	DTD0041 Transporter Info
Gene Name	ABCA3
Transporter Name	ATP-binding cassette sub-family A member 3
Gene ID	21
UniProt ID	Q99758
Modelled Structures of This DT
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Detail Information of Structural Model
Method	Homology modeling
Template PDB	5XJY_A		Identity	40%
Performance	Minimized Score	-1100.865 kcal/mol
	Ramachandra Favored	Poor
	QMEANBrane Quality	Medium
Ramachandran Plot
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	Ramz Z Score	-2.09 ±0.27
	Residues in Favored Region	708	Ramachandran favored	94.27%
	Number of Outliers	10	Ramachandran outliers	1.33%
Local Quality
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	QMEANBrane Score		0.69
AlphaFold Protein Structure Database	Q99758 Click to jump to the details page
SWISS-MODEL Database	Q99758 Click to jump to the details page
Experimental Structures of This DT
PDB ID	Scanning Method	Resolution	Expression System	Details	Ref
7W01	EM	3.3 Å	Homo sapiens	Click to Show/Hide the Details	[1]
Structure
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Corresponding chain	A
Sequence Length	1748		Mutation	No
7W02	EM	3.3 Å	Homo sapiens	Click to Show/Hide the Details	[1]
Structure
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Corresponding chain	A
Sequence Length	1748		Mutation	No
References
1	Cryo-EM structures of the human surfactant lipid transporter ABCA3. Sci Adv. 2022;8(14):eabn3727.

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