General Information of Drug Transporter (DT)
DT ID	DTD0021 Transporter Info
Gene Name	SLC15A1
Transporter Name	Peptide transporter 1
Gene ID	6564
UniProt ID	P46059
Modelled Structures of This DT
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Detail Information of Structural Model
Method	Homology modeling
Template PDB	6EI3_A; 5A9D_A; 2XUT_A		Identity	54.386; 67.021; 29.858%
Ramachandran Plot
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	Ramz Z Score	-0.73 ±0.3
	Residues in Favored Region	595	Ramachandran favored	95.66%
	Number of Outliers	7	Ramachandran outliers	1.13%
Local Quality
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	QMEANBrane Score		0.79
AlphaFold Protein Structure Database	P46059 Click to jump to the details page
SWISS-MODEL Database	P46059 Click to jump to the details page
Experimental Structures of This DT
PDB ID	Scanning Method	Resolution	Expression System	Details	Ref
7PMW	EM	4.1 Å	Homo sapiens	Click to Show/Hide the Details	[1]
Structure
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Corresponding chain	A
Sequence Length	708		Mutation	No
7PMX	EM	3.5 Å	Homo sapiens	Click to Show/Hide the Details	[1]
Structure
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Corresponding chain	A
Sequence Length	708		Mutation	No
7PN1	EM	3.9 Å	Homo sapiens	Click to Show/Hide the Details	[1]
Structure
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Corresponding chain	A
Sequence Length	708		Mutation	No
References
1	Structural snapshots of human PepT1 and PepT2 reveal mechanistic insights into substrate and drug transport across epithelial membranes. Sci Adv. 2021;7(45):eabk3259.

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