Drug Transporter (DT) Information

General Information of DT
DT ID DTD0505
Gene Name SLCO6A1
Protein Name Organic anion-transporting polypeptide 6A1
Gene ID
133482
UniProt ID
Q86UG4
TCDB ID
2.A.60.1.17
3D Structure

Modelled DT Structure

Method: multi-sequence alignment based machine learning

Detail: Structure Info

Synonyms CT48; Cancer/testis antigen 48; GST; OATP-I; OATP6A1; OATPY; Organic anion-transporting polypeptide I; SLC21A19; SLCO6A1; Solute carrier family 21 member 19; Solute carrier organic anion transporter family member 6A1
DT Family Organo Anion Transporter (OAT) Family ;
Tissue Specificity Strongly expressed in testis. Weakly expressedin spleen, brain, fetal brain and placenta. Detected in lungtumors.
Function This sodium-independent transporter mediates the transport of organic anion in plasma membrane.
Endogenous Substrate(s) Organoanions
Variability Data of This Drug Transporter (DT)

Regulatory Variability Data of This DT (VARIDT 4.0)

(α) Tissue Distribution Level of Organic anion-transporting polypeptide 6A1
Tissue Distribution Level (TD)

(β) Cell Distribution Level of Organic anion-transporting polypeptide 6A1
Cell Distribution Level (CD)

(γ) Organelle Distribution Level of Organic anion-transporting polypeptide 6A1
Organelle Distribution Level (Subc)

Regulatory Variability Data of This DT

(β) Post-translational Modification of Organic anion-transporting polypeptide 6A1
Post-translational Modification (PTM)

(δ) Epigenetic Regulation of Organic anion-transporting polypeptide 6A1
Epigenetic Regulation (EGR)

(ε) Exogenous Modulation of Organic anion-transporting polypeptide 6A1
Exogenous Modulation (EGM)

General Variability Data of This DT

(α) Genetic Polymorphisms of Organic anion-transporting polypeptide 6A1
Genetic Polymorphisms of This DT (GPD)

(β) Disease-specific Protein Abundances of Organic anion-transporting polypeptide 6A1
Disease-specific Protein Abundances of This DT (DPAD)

(γ) Species- and Tissue-specific DT Abundances
Species/Tissue-specific Protein Abundances of This DT (S/TPAD)

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