Drug Transporter (DT) Information

General Information of DT
DT ID DTD0344
Gene Name SLC39A3
Protein Name Zinc transporter ZIP3
Gene ID
29985
UniProt ID
Q9BRY0
TCDB ID
2.A.5.3.3
3D Structure

Modelled DT Structure

Method: multi-sequence alignment based machine learning

Detail: Structure Info

Synonyms SLC39A3; Solute carrier family 39 member 3; ZIP-3; ZIP3; Zinc transporter ZIP3
DT Family Zinc (Zn(2+))-Iron (Fe(2+)) Permease (ZIP) Family ;
Function This transporter mediates the influx of zinc.
Endogenous Substrate(s) Zn2+
Variability Data of This Drug Transporter (DT)

Regulatory Variability Data of This DT (VARIDT 4.0)

(α) Tissue Distribution Level of Zinc transporter ZIP3
Tissue Distribution Level (TD)

(β) Cell Distribution Level of Zinc transporter ZIP3
Cell Distribution Level (CD)

(γ) Organelle Distribution Level of Zinc transporter ZIP3
Organelle Distribution Level (Subc)

Regulatory Variability Data of This DT

(α) Microbiota Influence of Zinc transporter ZIP3
Microbiota Influence (MBI)

(β) Post-translational Modification of Zinc transporter ZIP3
Post-translational Modification (PTM)

(γ) Transcriptional Regulation of Zinc transporter ZIP3
Transcriptional Regulation (TSR)

(δ) Epigenetic Regulation of Zinc transporter ZIP3
Epigenetic Regulation (EGR)

(ε) Exogenous Modulation of Zinc transporter ZIP3
Exogenous Modulation (EGM)

General Variability Data of This DT

(α) Genetic Polymorphisms of Zinc transporter ZIP3
Genetic Polymorphisms of This DT (GPD)

(β) Disease-specific Protein Abundances of Zinc transporter ZIP3
Disease-specific Protein Abundances of This DT (DPAD)

(γ) Species- and Tissue-specific DT Abundances
Species/Tissue-specific Protein Abundances of This DT (S/TPAD)
Molecular Transporting Profile of This DT

Full List of Drug(s) Transported by This DT

 Withdrawn, Discontinued or Preclinical Drug

 Click to Show/Hide the Full List of Drug:           1 Drugs in Total
Drug Name Highest Status Detail Indication ICD 11 Ref
Zinc salts
 Preclinical Drug Info Arthritis FA5Z [1]
References
1 The SLC39 family of zinc transporters. Mol Aspects Med. 2013 Apr-Jun;34(2-3):612-9.

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