Drug Transporter (DT) Information

General Information of DT
DT ID DTD0308
Gene Name SLC35F3
Protein Name Putative thiamine transporter SLC35F3
Gene ID
148641
UniProt ID
Q8IY50
TCDB ID
2.A.7.24.8
3D Structure

Modelled DT Structure

Method: multi-sequence alignment based machine learning

Detail: Structure Info

Synonyms SLC35F3; Solute carrier family 35 member F3
DT Family Drug/Metabolite Transporter (DMT) Superfamily
Thiamine Pyrophosphate Transporter (TPPT) Family
Function This transporter may mediates the transport of thiamine.
Endogenous Substrate(s) Thiamine
Variability Data of This Drug Transporter (DT)

Regulatory Variability Data of This DT (VARIDT 4.0)

(α) Tissue Distribution Level of Putative thiamine transporter SLC35F3
Tissue Distribution Level (TD)

(β) Cell Distribution Level of Putative thiamine transporter SLC35F3
Cell Distribution Level (CD)

(γ) Organelle Distribution Level of Putative thiamine transporter SLC35F3
Organelle Distribution Level (Subc)

Regulatory Variability Data of This DT

(β) Post-translational Modification of Putative thiamine transporter SLC35F3
Post-translational Modification (PTM)

(γ) Transcriptional Regulation of Putative thiamine transporter SLC35F3
Transcriptional Regulation (TSR)

(δ) Epigenetic Regulation of Putative thiamine transporter SLC35F3
Epigenetic Regulation (EGR)

(ε) Exogenous Modulation of Putative thiamine transporter SLC35F3
Exogenous Modulation (EGM)

Structural Variability Data of This DT

(β) Inter-species Structural Differences
Inter-species Structural Differences (ISD)

General Variability Data of This DT

(α) Genetic Polymorphisms of Putative thiamine transporter SLC35F3
Genetic Polymorphisms of This DT (GPD)

(β) Disease-specific Protein Abundances of Putative thiamine transporter SLC35F3
Disease-specific Protein Abundances of This DT (DPAD)

(γ) Species- and Tissue-specific DT Abundances
Species/Tissue-specific Protein Abundances of This DT (S/TPAD)
Molecular Transporting Profile of This DT

Full List of Drug(s) Transported by This DT

 Approved Drug

 Click to Show/Hide the Full List of Drug:           1 Drugs in Total
Drug Name Highest Status Detail Indication ICD 11 Ref
Vitamin B1
 Approved Drug Info Vitamin B1 deficiency 5B5A [1]
References
1 Genetic implication of a novel thiamine transporter in human hypertension. J Am Coll Cardiol. 2014 Apr 22;63(15):1542-55.

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